Details of the Drug

General Information of Drug (ID: DMRKOS1)

Drug Name
Oxilofrine
Synonyms Oxilofrine hydrochloride; Carnigen (TN)
Indication
Disease Entry ICD 11 Status REF
Orthostatic hypotension BA21 Approved [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 181.23
Logarithm of the Partition Coefficient (xlogp) 0.6
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C10H15NO2
IUPAC Name
4-[(1R,2S)-1-hydroxy-2-(methylamino)propyl]phenol
Canonical SMILES
C[C@@H]([C@@H](C1=CC=C(C=C1)O)O)NC
InChI
InChI=1S/C10H15NO2/c1-7(11-2)10(13)8-3-5-9(12)6-4-8/h3-7,10-13H,1-2H3/t7-,10-/m0/s1
InChIKey
OXFGTKPPFSCSMA-XVKPBYJWSA-N
Cross-matching ID
PubChem CID
688009
ChEBI ID
CHEBI:134822
CAS Number
365-26-4
UNII
F49638UBDR
DrugBank ID
DB11610
TTD ID
D07QLG

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adrenergic receptor (ADR) TTVIREA NOUNIPROTAC Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015