Details of the Drug

General Information of Drug (ID: DMRPCF2)

Drug Name
MGCD265
Synonyms
MGCD-265; 875337-44-3; MGCD265; MGCD-265 analog; MGCD 265; N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide; UNII-93M6577H9D; CHEMBL254760; 93M6577H9D; n-(3-fluoro-4-(2-(1-methyl-1h-imidazol-4-yl)thieno(3,2-b)pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide; N-[(3-Fluoro-4-{[2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)carbamothioyl]-2-phenylacetamide
Indication
Disease Entry ICD 11 Status REF
Non-small-cell lung cancer 2C25.Y Phase 2 [1]
Solid tumour/cancer 2A00-2F9Z Phase 1 [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 517.6
Logarithm of the Partition Coefficient (xlogp) 4.9
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C26H20FN5O2S2
IUPAC Name
N-[[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]carbamothioyl]-2-phenylacetamide
Canonical SMILES
CN1C=C(N=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=S)NC(=O)CC5=CC=CC=C5)F
InChI
InChI=1S/C26H20FN5O2S2/c1-32-14-20(29-15-32)23-13-19-25(36-23)22(9-10-28-19)34-21-8-7-17(12-18(21)27)30-26(35)31-24(33)11-16-5-3-2-4-6-16/h2-10,12-15H,11H2,1H3,(H2,30,31,33,35)
InChIKey
UFICVEHDQUKCEA-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
24901704
ChEBI ID
CHEBI:91393
CAS Number
875337-44-3
TTD ID
D08FDX
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Protein kinase (PK) TTU8W4S NOUNIPROTAC Inhibitor [2]
Tyrosine-protein kinase UFO (AXL) TTZPY6J UFO_HUMAN Modulator [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Non-small-cell lung cancer
ICD Disease Classification 2C25.Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tyrosine-protein kinase UFO (AXL) DTT AXL 1.13E-65 -0.53 -2.04
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 144 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -0.598 5.4128 -1.0424 44.957
MEC1 CTRP2 3.1435 5.9341 2.908 20.1465
JM1 CTRP2 2.7828 5.0938 2.6922 22.0372
EoL-1 CTRP2 -10.5795 -9.149 -10.5795 99.6507
MV4-11 CTRP2 -4.4769 -0.7342 -4.4839 69.332
MOLM-13 CTRP2 -4.0449 -0.2246 -4.0554 66.5874
NCO2 CTRP2 -0.7342 1.4947 -0.7367 45.1663
Ku812 CTRP2 -0.5491 1.1007 -0.5493 43.9274
SEM CTRP2 -0.1156 5.7468 -0.5993 42.0898
ALL-SIL CTRP2 -0.1019 1.5614 -0.1024 40.9491
LAMA-84 CTRP2 -0.0414 4.2024 -0.2001 43.8976
JURL-MK1 CTRP2 0.1061 2.2384 0.1018 39.5754
MOLM-16 CTRP2 0.1324 5.4155 -0.2474 40.3415
EM-2 CTRP2 0.4478 3.2092 0.4188 37.3778
CML-T1 CTRP2 0.4957 3.0726 0.4752 37.0323
Mono-Mac-6 CTRP2 0.5197 34.988 -13.2551 46.9066
DoHH2 CTRP2 0.8877 7.4073 -0.0066 36.8557
Mono-Mac-1 CTRP2 0.9296 15.0458 -3.2013 41.6989
MOLM-6 CTRP2 1.0763 4.1842 0.9943 33.3675
KYO-1 CTRP2 1.0904 2.091 1.0904 33.0042
K-562 CTRP2 1.5196 3.7766 1.4948 30.2277
Peer CTRP2 1.5571 4.6508 1.4453 30.2695
Kasumi-1 CTRP2 1.9474 5.1684 1.7784 27.8683
HuT 78 CTRP2 1.9506 7.8694 0.9729 30.5149
GDM-1 CTRP2 1.9645 4.1028 1.9355 27.2782
BV-173 CTRP2 1.9944 5.0096 1.858 27.4442
PF-382 CTRP2 2.0005 4.7902 1.8996 27.2824
RPMI-8402 CTRP2 2.0472 3.6338 2.0415 26.649
Pfeiffer CTRP2 2.2303 3.152 2.2302 25.4102
Ri-1 CTRP2 2.2407 5.1017 2.1075 25.7941
NALM-6 CTRP2 2.2416 4.9933 2.1268 25.725
MOLT-3 CTRP2 2.3912 3.1793 2.3912 24.338
WSU-DLCL2 CTRP2 2.4081 3.9772 2.3994 24.2546
OCI-AML-3 CTRP2 2.4099 4.8374 2.3305 24.4823
SU-DHL-6 CTRP2 2.4292 5.2705 2.2802 24.5943
KMS-20 CTRP2 2.4531 5.0955 2.3375 24.3196
Daudi CTRP2 2.5364 3.6405 2.5354 23.3741
RPMI-8226 CTRP2 2.5552 5.063 2.4526 23.5946
697 CTRP2 2.6108 3.4337 2.6107 22.8753
KMS-11 CTRP2 2.618 6.4048 2.2007 24.2873
TALL-1 [Human adult T-ALL] CTRP2 2.6288 4.6765 2.5823 22.912
KMS-21-BM CTRP2 2.6547 5.7814 2.4135 23.4174
Mino CTRP2 2.7191 3.9077 2.7168 22.1613
KE-37 CTRP2 2.7275 3.4176 2.7275 22.0976
SUP-B15 CTRP2 2.7496 4.9561 2.6768 22.197
P31/FUJ CTRP2 2.76 4.3144 2.7465 21.9261
Ki-JK CTRP2 2.7732 4.4163 2.7546 21.8556
P12-Ichikawa CTRP2 2.7837 3.8902 2.7822 21.7283
Reh CTRP2 2.791 3.8688 2.7897 21.6787
OPM-2 CTRP2 2.8265 4.5061 2.8041 21.5131
Karpas-620 CTRP2 2.8593 4.619 2.8299 21.3184
NB4 CTRP2 2.8626 3.806 2.8621 21.1995
GA-10 CTRP2 2.867 4.4749 2.8482 21.2312
KO52 CTRP2 2.8692 5.1619 2.7742 21.4772
ST486 CTRP2 2.8749 4.6115 2.8467 21.2105
SU-DHL-4 CTRP2 2.8784 5.3696 2.7474 21.541
NOMO-1 CTRP2 2.975 7.2261 2.3112 22.8219
OCI-AML-2 CTRP2 2.981 4.0362 2.9793 20.4145
KMS-18 CTRP2 2.9836 5.0384 2.9153 20.6231
RS4;11 CTRP2 2.9851 4.9604 2.9272 20.5777
KMS-26 CTRP2 2.9852 4.2466 2.9796 20.3995
JVM-3 CTRP2 2.9892 6.8395 2.4635 22.2235
L-540 CTRP2 3.0002 5.1912 2.9102 20.5875
SUP-M2 CTRP2 3.006 4.5485 2.9877 20.3036
SU-DHL-1 CTRP2 3.0088 3.9077 3.0083 20.2252
SUP-T1 CTRP2 3.0523 4.8356 3.0127 20.0673
KE-97 CTRP2 3.1206 4.7666 3.0909 19.5786
F-36P CTRP2 3.1676 8.0466 2.198 22.6828
DEL CTRP2 3.1831 4.3804 3.1774 19.0814
SKM-1 CTRP2 3.3289 5.0798 3.2778 18.2642
PL21 CTRP2 3.3316 5.8923 3.124 18.7952
A4/Fukuda CTRP2 3.3523 5.8163 3.1655 18.5831
DND-41 CTRP2 3.378 6.7443 2.9172 19.4104
Kasumi-2 CTRP2 3.4466 5.9647 3.2307 18.0596
OCI-AML-5 CTRP2 3.4536 4.0713 3.4536 17.2603
BL-70 CTRP2 3.455 4.8494 3.4339 17.3221
HT CTRP2 3.4588 4.5274 3.454 17.2416
KMS-12-BM CTRP2 3.4677 5.7738 3.3014 17.7422
REC-1 CTRP2 3.4848 6.4655 3.1256 18.3267
Karpas-299 CTRP2 3.5043 8.2393 2.4709 20.7298
EB1 CTRP2 3.5746 6.215 3.3006 17.4188
SU-DHL-8 CTRP2 3.5805 6.3354 3.2707 17.51
CA46 CTRP2 3.5969 6.0183 3.3805 17.0617
JeKo-1 CTRP2 3.6808 6.7574 3.2402 17.3282
KMM-1 CTRP2 3.6856 8.3291 2.6208 19.6682
MOLT-16 CTRP2 3.6896 5.2585 3.6386 15.8608
LP-1 CTRP2 3.864 6.295 3.592 15.4876
HuNS1 CTRP2 3.8821 6.8521 3.4236 16.0611
MHH-CALL-3 CTRP2 3.8865 6.4229 3.5761 15.4794
MM1.S CTRP2 3.9148 5.8461 3.7713 14.6849
M-07e CTRP2 3.9692 6.7097 3.5685 15.2667
Ci-1 CTRP2 3.9753 6.9614 3.4832 15.5707
Hs 611.T CTRP2 4.0253 6.5804 3.6743 14.7087
KMS-27 CTRP2 4.0318 6.3458 3.7589 14.3757
SET-2 CTRP2 4.0327 6.8314 3.5931 14.992
OCI-M1 CTRP2 4.0962 6.3748 3.8196 13.9618
NU-DHL-1 CTRP2 4.1568 6.3245 3.9016 13.4803
KHM-1B CTRP2 4.1951 6.2249 3.9742 13.0998
NCI-H929 CTRP2 4.234 6.357 3.9752 12.9807
JJN-3 CTRP2 4.2638 6.822 3.8446 13.3837
MOLP-8 CTRP2 4.3155 6.1837 4.1178 12.215
OCI-Ly3 CTRP2 4.4195 6.183 4.2314 11.4884
L-428 CTRP2 4.4548 7.5073 3.7701 13.1485
EHEB CTRP2 4.4781 9.2987 2.98 16.2291
RPMI-6666 CTRP2 4.5348 6.8922 4.1071 11.6228
MC116 CTRP2 4.5689 5.3982 4.5541 9.8799
MOTN-1 CTRP2 4.5817 7.5297 3.8917 12.3351
SU-DHL-10 CTRP2 4.6037 5.5527 4.574 9.6988
TF-1 CTRP2 4.6045 7.7151 3.834 12.5038
P3HR-1 CTRP2 4.6265 7.3294 4.0243 11.6954
DB CTRP2 4.6817 6.7006 4.3378 10.3307
L-363 CTRP2 4.7391 6.7544 4.3783 10.0152
MHH-CALL-4 CTRP2 4.8672 7.0739 4.3831 9.6475
MOLP-2 CTRP2 4.9234 7.8025 4.1172 10.56
Namalwa CTRP2 4.9638 7.3898 4.3449 9.5462
A3/Kawakami CTRP2 4.9672 5.8894 4.9073 7.3831
THP-1 CTRP2 4.971 7.1093 4.4756 9.009
Karpas-422 CTRP2 5.0097 5.7591 4.9784 6.9999
AML-193 CTRP2 5.0383 9.1376 3.5961 12.4063
SIG-M5 CTRP2 5.0479 6.2993 4.878 7.247
RL CTRP2 5.049 7.8221 4.233 9.7811
CMK CTRP2 5.0729 7.537 4.3885 9.0946
OCI-Ly19 CTRP2 5.089 6.3964 4.8881 7.0904
SR CTRP2 5.1085 7.0845 4.6279 8.0473
HH [Human lymphoma] CTRP2 5.117 7.0903 4.6341 8.0009
HEL 92.1.7 CTRP2 5.1439 10.0092 3.2693 13.5025
SUP-HD1 CTRP2 5.2154 7.6947 4.4564 8.4685
Granta-519 CTRP2 5.2198 8.0343 4.3 9.0961
ME1 CTRP2 5.2259 8.577 4.0448 10.13
AMO1 CTRP2 5.2952 7.7429 4.5115 8.0515
HDLM-2 CTRP2 5.4088 11.9245 2.5592 15.7699
JVM-2 CTRP2 5.4309 9.9455 3.5616 13.4604
U266B1 CTRP2 5.4336 9.9285 3.5725 11.6207
HD-MY-Z CTRP2 5.5217 10.587 3.324 12.4569
HL-60 CTRP2 5.5753 6.7394 5.2566 4.3441
EJM CTRP2 5.937 8.2106 4.8705 5.1455
SK-MM-2 CTRP2 5.9703 11.4957 3.2568 11.8172
OCI-Ly10 CTRP2 6.0283 7.6552 5.2255 3.4733
Raji CTRP2 7.2813 11.246 4.3883 4.9034
MOLT-13 CTRP2 7.3283 10.6095 4.7226 3.5111
KM-H2 CTRP2 7.7365 9.8325 5.3055 1.1507
KCL-22 CTRP2 7.9456 9.8656 5.3905 0.7232
HEL CTRP2 8.0865 9.2823 5.6608 0.0972
Jurkat CTRP2 8.3246 9.6448 5.6212 0.1029
⏷ Show the Full List of 144 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 4.0916 6.4343 3.7954 14.0648
TE15 CTRP2 6.1615 9.4839 4.4212 6.5997
KYSE-140 CTRP2 4.7899 16.2244 -0.1255 26.0795
KYSE-70 CTRP2 4.898 6.8087 4.5252 9.0114
KYSE-410 CTRP2 4.8985 9.8648 3.1117 14.7004
OE33 CTRP2 5.0509 13.6319 1.3939 20.8448
TE-5 CTRP2 5.2101 8.1073 4.2557 9.3005
TE-6 CTRP2 5.2341 8.3156 4.1787 9.5599
OE21 CTRP2 5.5265 9.5837 3.8266 10.3679
TE-11 CTRP2 5.7149 8.5412 4.5118 7.1075
KYSE-520 CTRP2 5.8516 9.7965 4.0053 8.9474
TE-1 CTRP2 5.8736 9.0287 4.4076 7.2167
COLO 680N CTRP2 5.9378 9.2713 4.3413 7.3666
EC-GI-10 CTRP2 6.0524 9.1733 4.4866 6.5321
OE19 CTRP2 6.0675 7.4223 5.3746 2.7713
TE-4 CTRP2 6.1832 8.4178 4.9713 4.2496
TE-14 CTRP2 6.3266 10.303 4.1454 7.4511
KYSE-510 CTRP2 6.3917 9.881 4.4073 6.2391
KYSE-30 CTRP2 6.8434 11.1626 4.1168 6.6805
KYSE-150 CTRP2 7.4768 11.8966 4.2088 5.3458
KYSE-450 CTRP2 7.5632 12.3411 4.0542 5.8412
TE-9 CTRP2 7.7611 11.7361 4.4702 3.9433
TE-10 CTRP2 8.4794 13.9617 3.8842 5.3008
KYSE-180 CTRP2 8.6264 11.0952 5.2105 0.7166
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 5.9402 8.5883 4.6846 5.9197
SNU-410 CTRP2 2.5525 6.7096 2.0332 25.0832
KP-4 CTRP2 3.2414 8.6923 2.0049 23.1809
HPAC CTRP2 4.1834 6.1295 3.9895 13.0794
KP-3 CTRP2 4.3631 10.1189 2.4793 18.4735
HuP-T4 CTRP2 4.597 11.6506 1.9595 19.8738
BxPC-3 CTRP2 4.9373 8.8115 3.6566 12.3953
PK-59 CTRP2 4.9549 8.8187 3.6702 12.2984
HPAF-II CTRP2 4.9745 8.2144 3.9762 11.005
MIA PaCa-2 CTRP2 5.0239 7.2409 4.4723 8.8841
Panc 10.05 CTRP2 5.315 8.7591 4.0398 9.947
Panc 03.27 CTRP2 5.3291 7.4567 4.6797 7.2846
CFPAC-1 CTRP2 5.3676 8.8148 4.0614 9.7393
PSN1 CTRP2 5.3691 9.8125 3.5717 11.7637
SU.86.86 CTRP2 5.4444 8.035 4.5136 7.6946
DAN-G CTRP2 5.4965 8.7388 4.2171 8.8076
Panc 08.13 CTRP2 5.5332 7.8792 4.6725 6.8356
Panc 04.03 CTRP2 5.7669 7.961 4.846 5.5997
SW1990 CTRP2 5.7891 9.2869 4.2057 8.2349
Hs 766T CTRP2 5.8578 8.0665 4.8739 5.2926
PaTu 8988s CTRP2 5.8673 7.8267 5.0017 4.7373
AsPC-1 CTRP2 5.9194 8.8125 4.5548 6.5065
PK-45H CTRP2 5.9857 12.3519 2.8416 13.4658
Capan-2 CTRP2 6.0714 11.2638 3.4572 10.7958
PaTu 8988t CTRP2 6.1244 6.9572 5.6529 1.4976
L3.3 CTRP2 6.1382 8.3031 4.9922 4.2449
PaTu 8902 CTRP2 6.234 7.3797 5.5275 1.8332
TCC-Pan2 CTRP2 6.2361 9.9843 4.2318 7.2552
Capan-1 CTRP2 6.2747 7.7891 5.3558 2.4793
Panc 02.03 CTRP2 6.4249 8.2044 5.2627 2.6201
KP-2 CTRP2 6.9902 10.7444 4.4284 5.1692
Panc 05.04 CTRP2 7.2964 12.2238 3.9258 6.7492
HuP-T3 CTRP2 7.3088 12.4619 3.8186 7.1641
YAPC CTRP2 7.4081 9.7263 5.1774 1.7052
SNU-213 CTRP2 7.495 11.5009 4.4097 4.5224
QGP-1 CTRP2 7.6548 9.1491 5.5419 0.4056
SUIT-2 CTRP2 8.2444 9.8232 5.5297 0.2189
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.6036 7.8983 4.7286 6.9221
COLO 741 CTRP2 1.2571 11.5098 -1.2651 38.1219
COLO 792 CTRP2 3.673 7.6486 2.8926 18.6653
G-361 CTRP2 3.743 5.7147 3.6145 15.7755
WM266-4 CTRP2 4.4238 7.8224 3.6017 13.8932
Hs 852.T CTRP2 4.5909 7.3907 3.9612 12.0374
MDA-MB-435S CTRP2 4.7776 7.4419 4.1316 10.8745
LOX-IMVI CTRP2 4.8861 7.1384 4.3752 9.6283
WM88 CTRP2 4.9275 7.8824 4.0845 10.6819
Malme-3M CTRP2 5.0884 11.4081 2.5294 16.5856
Hs 936.T CTRP2 5.2144 8.4968 4.0727 10.0414
WM115 CTRP2 5.2276 6.1989 5.1065 5.8723
SK-MEL-5 CTRP2 5.2557 7.0186 4.8075 6.9533
MeWo CTRP2 5.2781 7.4691 4.6237 7.6364
IGR-37 CTRP2 5.3367 8.0888 4.3857 8.47
HT-144 CTRP2 5.3905 6.4552 5.188 5.1008
A-375 CTRP2 5.3963 7.484 4.7324 6.9077
HMCB CTRP2 5.4449 9.1934 3.9461 10.047
Hs 944.T CTRP2 5.5398 10.4553 3.4055 12.0833
WM1799 CTRP2 5.5806 7.4051 4.9472 5.5927
Hs 940.T CTRP2 5.6159 7.7338 4.8206 6.0355
UACC-62 CTRP2 5.6549 7.9031 4.7734 6.1451
Hs 294T CTRP2 5.6797 6.788 5.3375 3.7591
WM983B CTRP2 5.6833 8.597 4.4559 7.4081
WM793 CTRP2 5.7442 7.6812 4.9641 5.1555
Mel JuSo CTRP2 5.7528 8.2625 4.6839 6.3076
COLO 829 CTRP2 5.77 7.9248 4.8667 5.5066
Hs 895.T CTRP2 5.9517 13.8782 2.0499 16.5883
IGR-1 CTRP2 5.9938 7.088 5.4799 2.4723
COLO 800 CTRP2 6.0518 8.8962 4.6246 5.9533
K029AX CTRP2 6.0641 7.1763 5.4948 2.2725
A101D CTRP2 6.0911 7.2538 5.4781 2.2917
SK-MEL-3 CTRP2 6.0987 10.529 3.8472 9.1234
SK-MEL-1 CTRP2 6.1356 8.3172 4.9831 4.2879
SK-MEL-2 CTRP2 6.2231 7.7065 5.3571 2.5619
A2058 CTRP2 6.2264 9.4283 4.5016 6.1416
IGR-39 CTRP2 6.2338 7.6425 5.3972 2.376
Hs 688(A).T CTRP2 6.4001 9.9582 4.3755 6.3571
SK-MEL-24 CTRP2 6.4189 9.2864 4.7239 4.8682
CJM [Human melanoma] CTRP2 6.4216 8.9456 4.8949 4.1506
RVH-421 CTRP2 6.4888 11.306 3.7742 8.7061
SK-MEL-30 CTRP2 6.5191 9.1909 4.8471 4.1873
IPC-298 CTRP2 6.6958 8.8884 5.1218 2.7864
SK-MEL-31 CTRP2 6.8084 9.5803 4.8656 3.6604
WT2-iPS CTRP2 6.8228 8.5934 5.3454 1.7317
SK-MEL-28 CTRP2 6.8287 9.8882 4.7304 4.1807
UACC-257 CTRP2 7.3074 11.9862 4.0489 6.2342
Hs 934.T CTRP2 7.3811 10.6608 4.7324 3.4052
Mel Ho CTRP2 8.3749 9.9272 5.5418 0.1707
Hs 839.T CTRP2 13.0462 32.0826 -1.7039 16.8954
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 4.7106 6.9037 4.289 10.4375
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MHH-NB-11 CTRP2 1.3666 6.0509 0.9377 32.5535
IMR-32 CTRP2 2.5616 3.0353 2.5616 23.2029
NB1 CTRP2 3.6448 5.3777 3.5729 16.2315
KP-N-YN CTRP2 3.6775 6.8852 3.1913 17.5207
KP-N-SI9s CTRP2 3.931 9.4078 2.3886 19.9062
SK-N-BE(2) CTRP2 3.9612 8.7029 2.7391 18.4824
SK-N-SH CTRP2 3.9899 6.8832 3.528 15.36
Kelly CTRP2 4.0546 5.3324 4.0178 13.381
SK-N-FI CTRP2 4.5863 6.2738 4.385 10.4282
NH-6 CTRP2 4.818 8.1046 3.873 11.8062
SK-N-AS CTRP2 5.3681 7.8719 4.52 7.8444
CHP-212 CTRP2 5.4692 8.8249 4.1498 9.1472
SK-N-DZ CTRP2 5.5312 7.1187 5.0366 5.3432
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 3.3267 5.1597 3.2649 18.3154
SNU-478 CTRP2 4.3513 7.0623 3.8452 13.1372
HuH-28 CTRP2 4.8314 6.7472 4.4793 9.3714
HuCC-T1 CTRP2 4.9983 10.358 2.9639 15.0669
SNU-1196 CTRP2 5.0506 8.0436 4.131 10.191
SNU-869 CTRP2 5.9652 6.8432 5.5772 2.1221
SNU-308 CTRP2 6.0825 8.8975 4.6495 5.79
SNU-245 CTRP2 6.6376 10.7996 4.1413 6.9216
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U2OS CTRP2 2.2068 5.1939 2.0541 26.087
Hs 888.T CTRP2 2.2949 10.6716 0.1658 31.7586
SK-ES-1 CTRP2 3.6697 5.6242 3.5542 16.2177
SK-N-MC CTRP2 3.8839 5.9242 3.7183 14.9698
CAL-78 CTRP2 4.2728 6.795 3.8643 13.2836
TC71 CTRP2 4.3646 8.0503 3.4406 14.6834
A-673 CTRP2 4.5292 6.6731 4.1848 11.3423
SW1353 CTRP2 5.1123 8.4036 4.0199 10.4969
SaOS-2 CTRP2 5.3751 8.5936 4.1766 9.2453
HOS CTRP2 5.6248 8.7212 4.3421 8.0085
G-292 clone A141B1 CTRP2 5.6676 8.863 4.3099 8.0517
MG-63 CTRP2 5.7144 8.6137 4.4754 7.2608
SJSA-1 CTRP2 5.7858 10.0732 3.8106 9.894
Hs 822.T CTRP2 6.6155 12.3126 3.3726 10.133
MHH-ES-1 CTRP2 7.9506 11.883 4.5193 3.5305
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1954 CTRP2 4.0075 7.5791 3.273 16.2868
SK-BR-3 CTRP2 4.7318 23.879 -3.989 33.8238
BT-20 CTRP2 4.9382 7.7564 4.1531 10.3788
Hs 578T CTRP2 4.9483 5.9762 4.8661 7.5879
HCC2218 CTRP2 5.0298 8.5748 3.8588 11.351
MDA-MB-468 CTRP2 5.1001 6.9554 4.6754 7.8818
EFM-192A CTRP2 5.1297 8.6115 3.9368 10.797
HCC1143 CTRP2 5.3165 11.4043 2.736 15.2717
ZR-75-1 CTRP2 5.3329 11.1933 2.8554 14.7608
AU565 CTRP2 5.3513 11.8666 2.5373 15.9791
MDA-MB-231 CTRP2 5.3533 8.5205 4.1919 9.2314
BT-549 CTRP2 5.4044 8.1047 4.4421 8.0814
HCC1937 CTRP2 5.4106 9.2652 3.8795 10.3989
HCC1500 CTRP2 5.4574 8.2211 4.4351 7.9895
HCC202 CTRP2 5.5398 11.79 2.741 14.7756
HCC1428 CTRP2 5.5732 10.1605 3.5816 11.286
T-47D CTRP2 5.8984 13.6363 2.1261 16.4117
ZR-75-30 CTRP2 5.9261 8.2953 4.8189 5.384
HDQ-P1 CTRP2 5.944 9.2914 4.3365 7.3746
HCC1419 CTRP2 5.9706 9.5961 4.2067 7.8669
BT-474 CTRP2 5.981 9.1658 4.4306 6.9064
HCC1806 CTRP2 6.0514 8.7281 4.7084 5.6022
CAL-85-1 CTRP2 6.1298 8.7458 4.7642 5.2185
CAL-120 CTRP2 6.1351 8.0316 5.1253 3.6916
JIMT-1 CTRP2 6.2165 9.4107 4.5024 6.1564
MDA-MB-361 CTRP2 6.3437 8.3326 5.1391 3.2652
HCC38 CTRP2 6.4935 8.7431 5.0486 3.3945
CAL-51 CTRP2 6.6994 10.969 4.1044 6.9705
Hs 578Bst CTRP2 6.9892 11.2146 4.1982 6.1125
KPL-1 CTRP2 7.1435 7.7887 5.8374 0.0458
CAL-148 CTRP2 7.7278 9.2094 5.5498 0.3556
HMC-1-8 CTRP2 8.0313 9.1531 5.6853 0.0687
CAMA-1 CTRP2 8.1371 14.4492 3.4321 7.4877
HCC1395 CTRP2 8.1502 13.3822 3.9469 5.4722
MCF-7 CTRP2 8.1674 10.2855 5.3243 0.6734
BT 271 CTRP2 3.4908 17.3324 -1.8472 33.0113
BT 440 CTRP2 3.571 6.6658 3.1531 17.9717
BT 239 CTRP2 3.7746 5.8044 3.6284 15.628
BT 131 CTRP2 3.9646 11.0108 1.6695 22.4652
BT 172 CTRP2 4.2124 10.0445 2.3686 19.2697
BT 231 CTRP2 4.2433 8.8716 2.9469 16.9452
BT 416 CTRP2 4.5444 7.6809 3.7875 12.8443
BT 504 CTRP2 4.7147 8.4386 3.6156 13.0996
BT164 CTRP2 4.7691 9.2394 3.2904 14.2821
BT 228 CTRP2 4.9602 8.1899 3.9736 11.0501
BT 428 CTRP2 5.0235 8.3968 3.9376 11.0443
BT147 CTRP2 5.0318 9.3785 3.4731 12.9243
BT 112 CTRP2 5.4697 9.0758 4.0266 9.6584
BT 245 CTRP2 5.7417 18.3935 -0.3841 24.739
BT 330 CTRP2 5.9631 15.0702 1.4636 18.669
BT 145 CTRP2 6.1447 9.418 4.4404 6.5506
BT 248 CTRP2 6.2008 8.1634 5.1122 3.6267
BT 187 CTRP2 6.2496 12.4584 3.0067 12.2918
BT 216 CTRP2 6.4536 11.5957 3.602 9.4819
BT 422 CTRP2 6.4926 10.5967 4.1301 7.2188
BT 333 CTRP2 6.6383 10.0867 4.4944 5.4545
BT 139 CTRP2 6.9242 11.0973 4.2084 6.1732
BT 482 CTRP2 6.9456 9.6316 4.9348 3.1845
BT 320 CTRP2 7.0015 9.1478 5.1993 2.0741
BT 159 CTRP2 7.0191 13.6965 2.9971 10.9415
BT 224 CTRP2 7.1395 12.0419 3.9021 7.0876
BT 444 CTRP2 7.1818 10.6347 4.614 4.1388
BT 359 CTRP2 7.2202 13.9554 3.021 10.508
BT 286 CTRP2 7.2254 13.1147 3.4387 8.831
BT 498 CTRP2 7.332 8.7787 5.543 0.5804
BT 340 CTRP2 7.8601 15.127 2.9129 9.9088
BT 179 CTRP2 8.6345 15.8976 3.0732 8.1783
BT 328 CTRP2 8.7869 15.8227 3.2083 7.4674
BT 232 CTRP2 9.5485 22.4137 0.5641 15.4695
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 7.47 13.3153 3.5176 8.1284
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SF539 CTRP2 2.6019 8.2093 1.5349 26.6757
42-MG-BA CTRP2 3.3461 8.0845 2.3702 21.5442
SW1783 CTRP2 3.5282 9.1355 2.1057 22.0272
KNS-60 CTRP2 4.0785 7.1445 3.5232 15.1289
D283 Med CTRP2 4.0791 6.2151 3.8507 13.8984
GaMG CTRP2 4.2273 6.3044 3.9847 12.9656
SNB-75 CTRP2 4.3797 7.0474 3.8812 12.9201
SF126 CTRP2 4.4491 7.4809 3.7754 13.143
SW1088 CTRP2 4.5573 9.5771 2.925 16.2546
Hs 683 CTRP2 4.7312 8.3204 3.6869 12.7718
SF268 CTRP2 4.743 9.9203 2.9379 15.7607
ONS-76 CTRP2 4.9303 7.7694 4.1393 10.454
SNU-489 CTRP2 4.9662 7.1099 4.4703 9.0427
T98G CTRP2 5.0927 8.6004 3.9069 11.006
DK-MG CTRP2 5.2009 14.5619 1.0637 21.6197
YH-13 CTRP2 5.2463 9.2853 3.7187 11.4284
SNU-201 CTRP2 5.2667 6.9437 4.8519 6.7485
CAS-1 CTRP2 5.2724 7.0667 4.8028 6.9292
GB-1 CTRP2 5.3662 9.1629 3.8892 10.4563
SNU-738 CTRP2 5.3717 7.6084 4.6495 7.3053
DBTRG-05MG CTRP2 5.3747 9.0032 3.9755 10.0796
KNS-81 CTRP2 5.6821 12.091 2.7141 14.5862
M059K CTRP2 5.7128 7.4017 5.0728 4.7725
YKG-1 CTRP2 5.8467 9.0723 4.3627 7.4596
8-MG-BA CTRP2 5.9521 9.1094 4.4343 6.9477
Becker CTRP2 5.9562 12.7588 2.6134 14.427
U-118MG CTRP2 5.9815 13.1681 2.43 15.0899
KALS-1 CTRP2 6.0057 7.7277 5.1703 3.7496
A-172 CTRP2 6.1053 9.23 4.5021 6.3661
TM-31 CTRP2 6.2107 8.5655 4.9196 4.4166
GMS-10 CTRP2 6.3471 8.953 4.834 4.5328
Daoy CTRP2 6.6149 12.5405 3.2587 10.5982
SNU-626 CTRP2 6.849 11.5259 3.9419 7.3926
SF295 CTRP2 6.8995 14.1775 2.6666 12.4483
NMC-G1 CTRP2 6.9676 8.5406 5.4558 1.1603
KG-1-C CTRP2 6.9729 10.6962 4.4395 5.1497
CCF-STTG1 CTRP2 7.0251 11.9124 3.8822 7.3506
KNS-42 CTRP2 7.1133 9.6773 5.0227 2.6166
U-251MG CTRP2 7.179 11.5488 4.1708 5.9325
GOS-3 CTRP2 7.3843 10.0185 5.0318 2.2601
SNU-1105 CTRP2 7.5984 8.8695 5.624 0.2729
SNU-466 CTRP2 7.7633 8.7212 5.738 0.0558
LN-18 CTRP2 8.2454 9.2076 5.7394 0.0191
LN-229 CTRP2 8.3026 10.0137 5.4835 0.2779
U-87MG ATCC CTRP2 10.23 21.306 1.5564 11.413
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KLE CTRP2 3.5112 6.7037 3.0753 18.4353
AN3-CA CTRP2 3.6147 6.9577 3.0973 18.0535
JHUEM-1 CTRP2 4.3214 6.1927 4.1215 12.1838
MFE-296 CTRP2 4.3791 8.2608 3.3612 14.9607
RL95-2 CTRP2 4.3988 7.4843 3.7216 13.4876
HEC-1-A CTRP2 4.4719 7.7283 3.6923 13.4094
JHUEM-7 CTRP2 4.6791 9.368 3.1422 15.094
HEC-50B CTRP2 4.7023 8.9614 3.358 14.1693
HEC-151 CTRP2 5.205 7.2432 4.6551 7.6916
ESS-1 CTRP2 5.7428 7.315 5.1431 4.4136
JHUEM-3 CTRP2 6.2076 7.8743 5.2616 2.9885
MFE-319 CTRP2 6.2666 7.827 5.3308 2.5972
EN CTRP2 6.5959 11.5763 3.7236 8.7255
EFE-184 CTRP2 6.8071 9.3702 4.9662 3.2543
HEC-251 CTRP2 7.5205 9.0509 5.521 0.5264
HEC-6 CTRP2 7.8621 9.0927 5.6454 0.1426
HEC-265 CTRP2 7.9816 9.0806 5.6925 0.0686
HEC-1-B CTRP2 8.0452 12.8442 4.1322 4.8908
HEC-108 CTRP2 8.1193 9.3707 5.6422 0.098
HEC-59 CTRP2 8.1305 9.25 5.687 0.0561
JHUEM-2 CTRP2 8.7693 10.4925 5.4887 0.1712
Ishikawa (Heraklio) 02 ER- CTRP2 7.3845 8.5132 5.6698 0.243
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UO-31 CTRP2 3.2093 7.3442 2.5187 21.3789
KMRC-3 CTRP2 4.5422 7.9996 3.6439 13.4194
VMRC-RCW CTRP2 4.5739 7.1573 4.0416 11.7687
KMRC-20 CTRP2 4.7496 8.0735 3.8191 12.1938
KMRC-2 CTRP2 4.9548 6.7089 4.6254 8.4689
KMRC-1 CTRP2 5.0742 6.8824 4.6797 7.9337
OS-RC-2 CTRP2 5.1899 9.3258 3.6466 11.8522
VMRC-RCZ CTRP2 5.2756 7.4293 4.6399 7.5769
786-O CTRP2 5.5493 9.1151 4.0791 9.2673
CAL-54 CTRP2 5.5712 7.5978 4.8451 6.0352
TUHR14TKB CTRP2 5.6647 11.771 2.8588 14.046
TUHR4TKB CTRP2 5.9323 8.7101 4.617 6.2198
769-P CTRP2 5.9369 8.1762 4.8876 5.0739
SNU-1272 CTRP2 6.0463 7.1598 5.4882 2.3342
A-498 CTRP2 6.1201 8.2654 4.9964 4.2612
BFTC-909 CTRP2 6.3028 8.5909 4.9796 4.0013
TUHR10TKB CTRP2 6.6562 10.0183 4.5414 5.23
RCC10RGB CTRP2 6.8263 9.7208 4.81 3.8599
ACHN CTRP2 6.8571 12.0496 3.6893 8.4176
Caki-1 CTRP2 6.8716 10.3428 4.5395 4.8962
Caki-2 CTRP2 7.0198 10.7593 4.4421 5.0686
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-175 CTRP2 0.3139 9.0834 -1.2396 41.3722
NCI-H716 CTRP2 1.1735 3.9708 1.1191 32.6308
SW48 CTRP2 2.6926 3.7859 2.6914 22.3341
LoVo CTRP2 2.8388 6.1118 2.5275 22.4436
GP2d CTRP2 3.1078 5.9971 2.8524 20.4552
KM12 CTRP2 3.825 8.1385 2.847 18.4262
COLO 320 CTRP2 3.9326 6.6133 3.5626 15.3944
SW620 CTRP2 3.9391 7.1047 3.3901 16.0265
COLO205 CTRP2 4.1021 5.8443 3.9758 13.3774
T84 CTRP2 4.147 7.0832 3.6199 14.568
NCI-H747 CTRP2 4.4391 6.7931 4.0433 12.134
SW948 CTRP2 4.6796 6.2248 4.502 9.7211
SNU-C5 CTRP2 4.7512 8.291 3.7203 12.5875
SK-CO-1 CTRP2 4.8035 7.0321 4.3341 10.0098
MDST8 CTRP2 4.8203 7.3105 4.2329 10.3626
LS513 CTRP2 4.8452 6.6459 4.5334 9.1259
C2BBe1 CTRP2 4.8725 7.9277 4.0088 11.1235
OUMS-23 CTRP2 4.9683 7.3602 4.3627 9.4635
SNU-C2A CTRP2 4.9723 7.7131 4.2071 10.0764
SNU-61 CTRP2 4.9898 7.0482 4.5213 8.7793
CL-11 CTRP2 5.0615 7.6902 4.3066 9.4529
HCT 15 CTRP2 5.1436 7.8416 4.3171 9.2092
SNU-407 CTRP2 5.1722 7.117 4.6786 7.6815
SW1116 CTRP2 5.2363 7.6126 4.5155 8.1778
SNU-C1 CTRP2 5.2878 8.8286 3.9805 10.2537
SNU-1033 CTRP2 5.3278 7.5895 4.6159 7.5473
SW1417 CTRP2 5.4595 8.2582 4.4189 8.0521
RKO CTRP2 5.5591 9.1121 4.0895 9.2032
COLO 678 CTRP2 5.6096 8.9308 4.2246 8.5313
LS411N CTRP2 5.8587 7.2726 5.2694 3.6347
LS1034 CTRP2 5.8595 7.0939 5.3586 3.2608
RCM-1 [Human ESC] CTRP2 5.9015 7.7813 5.0541 4.4469
HT-55 CTRP2 6.0543 8.1473 5.0012 4.3657
HCC-56 CTRP2 6.0651 6.87 5.6487 1.6239
NCI-H508 CTRP2 6.1042 8.2958 4.9682 4.4096
LS123 CTRP2 6.1938 8.9183 4.73 5.2432
DLD-1 CTRP2 6.4771 8.93 4.9444 3.8526
SNU-C4 CTRP2 6.8705 9.1456 5.1164 2.5647
SNU-503 CTRP2 7.2251 9.0697 5.3655 1.2256
HCT 8 CTRP2 7.2957 11.4167 4.316 5.1734
HCT 116 CTRP2 7.7556 9.037 5.6249 0.2013
HT115 CTRP2 7.8689 9.4361 5.5229 0.3545
COLO201 CTRP2 8.0164 13.003 4.0392 5.2871
HT-29 CTRP2 8.0378 9.2111 5.6679 0.0841
CW-2 CTRP2 8.0452 11.7914 4.6174 3.0603
LS180 CTRP2 8.1549 9.3661 5.6563 0.079
CCK-81 CTRP2 8.2424 10.6063 5.2311 0.8737
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Li-7 CTRP2 2.8884 7.6182 2.0713 23.946
Hep-G2 CTRP2 3.7638 7.2402 3.1508 17.4287
SNU-878 CTRP2 3.9766 5.895 3.8267 14.2968
JHH-2 CTRP2 3.9891 5.5145 3.9207 13.9261
SNU-182 CTRP2 4.0176 8.7163 2.7903 18.1369
HuH-6 CTRP2 4.0324 8.7696 2.7813 18.1334
JHH-1 CTRP2 4.436 6.5384 4.1331 11.8037
SNU-761 CTRP2 4.873 7.6023 4.1575 10.5257
JHH-5 CTRP2 4.9286 6.823 4.5517 8.8252
SNU-886 CTRP2 5.073 6.9129 4.6654 7.9929
PLC/PRF/5 CTRP2 5.0997 7.1277 4.5998 8.1816
JHH-4 CTRP2 5.1213 8.2482 4.1028 10.1366
HLF CTRP2 5.1867 7.8182 4.3703 8.8883
SNU-423 CTRP2 5.222 6.9486 4.804 7.0544
HuH-1 CTRP2 5.554 7.7279 4.7657 6.4029
SNU-449 CTRP2 5.6417 8.1934 4.6182 6.8201
JHH-6 CTRP2 6.245 7.3505 5.5501 1.7213
SNU-475 CTRP2 6.3931 8.4014 5.1424 3.1692
SNU-387 CTRP2 6.4583 10.9479 3.9285 8.1194
SK-HEP-1 CTRP2 7.0041 11.0261 4.301 5.6685
Hep 3B2.1-7 CTRP2 8.0092 16.6422 2.2804 12.0628
SNU-398 CTRP2 8.633 10.6514 5.3806 0.355
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 142 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EBC-1 CTRP2 -4.3978 -1.447 -4.3989 69.2777
NCI-H1703 CTRP2 -0.0664 15.3033 -4.3123 45.4571
DMS 53 CTRP2 0.2749 8.4436 -1.0384 41.2148
NCI-H1975 CTRP2 0.97 3.8517 0.9164 33.9821
NCI-H1385 CTRP2 1.1533 4.7162 1.0018 33.0805
NCI-H810 CTRP2 1.8528 3.8997 1.8323 27.9935
NCI-H2286 CTRP2 2.7725 6.5327 2.3293 23.3575
NCI-H1341 CTRP2 3.1036 5.1866 3.022 19.8698
HCC44 CTRP2 3.243 5.3086 3.152 18.9738
HOP-92 CTRP2 3.2989 8.7196 2.0527 22.8471
NCI-H1573 CTRP2 3.3122 13.5921 -0.1931 29.8351
NCI-H69 CTRP2 3.3422 6.2366 3.0407 19.0633
HCC15 CTRP2 3.4152 5.3031 3.3381 17.7787
SHP-77 CTRP2 3.4337 5.1661 3.3781 17.5813
PC-14 CTRP2 3.467 6.3576 3.1402 18.3265
LXF 289 CTRP2 3.5048 5.8587 3.3213 17.5567
HCC2279 CTRP2 3.5712 9.094 2.1679 21.6815
NCI-H1581 CTRP2 3.5882 8.2589 2.5499 20.202
DV-90 CTRP2 3.5966 6.4624 3.2482 17.5449
NCI-H1184 CTRP2 3.6414 7.1153 3.0676 18.0892
RERF-LC-MS CTRP2 3.8288 8.7219 2.5959 19.3813
NCI-H1755 CTRP2 4.0304 6.0621 3.8416 14.0785
NCI-H1155 CTRP2 4.0734 7.0333 3.5608 14.9995
CAL-12T CTRP2 4.1025 11.8862 1.3809 23.1203
NCI-H2087 CTRP2 4.1122 11.5363 1.559 22.4829
NCI-H2081 CTRP2 4.1185 6.9207 3.6519 14.5257
NCI-H526 CTRP2 4.1209 6.4433 3.8242 13.8723
NCI-H2023 CTRP2 4.125 7.5509 3.4079 15.446
NCI-H23 CTRP2 4.1605 6.6831 3.7844 13.9057
NCI-H211 CTRP2 4.1887 7.6631 3.4273 15.199
NCI-H1092 CTRP2 4.2178 9.8802 2.4516 18.9388
NCI-H727 CTRP2 4.232 6.9205 3.7734 13.7443
NCI-H1435 CTRP2 4.2802 6.7896 3.8743 13.2248
NCI-H661 CTRP2 4.3149 7.8589 3.4738 14.6821
Calu-3 CTRP2 4.3459 8.0625 3.4161 14.8288
NCI-H446 CTRP2 4.3639 6.3596 4.1156 12.079
NCI-H841 CTRP2 4.4229 7.8128 3.605 13.8821
LOU-NH91 CTRP2 4.476 9.057 3.0915 15.7907
SK-LU-1 CTRP2 4.4959 7.5687 3.7864 12.9756
NCI-H1944 CTRP2 4.5084 6.876 4.0854 11.7795
NCI-H2110 CTRP2 4.5141 7.568 3.8055 12.8526
NCI-H1694 CTRP2 4.5315 6.0763 4.3845 10.5941
NCI-H1563 CTRP2 4.5635 7.8909 3.7141 13.0858
COLO 668 CTRP2 4.5833 8.3228 3.5385 13.7363
RERF-LC-Ad2 CTRP2 4.608 8.9212 3.2848 14.6934
NCI-H1568 CTRP2 4.6294 7.1359 4.1087 11.3577
VMRC-LCD CTRP2 4.6687 6.8911 4.2497 10.7043
NCI-H524 CTRP2 4.6877 6.6118 4.3777 10.1623
Lu-99 CTRP2 4.6963 7.8287 3.8767 12.0976
A-549 CTRP2 4.7226 6.5522 4.4371 9.8383
HARA [Human squamous cell lung carcinoma] CTRP2 4.7588 8.0671 3.8313 12.1219
NCI-H1355 CTRP2 4.7947 7.7938 3.992 11.3865
DMS 79 CTRP2 4.8078 8.1106 3.8601 11.8836
NCI-H647 CTRP2 4.8531 7.7751 4.0593 10.9695
RERF-LC-A1 CTRP2 4.9295 8.1347 3.9693 11.1423
NCI-H2141 CTRP2 4.9327 8.1305 3.9745 11.1135
COR-L51 CTRP2 4.937 6.9103 4.5246 8.9077
EKVX CTRP2 4.9568 9.9513 3.1241 14.5158
ChaGo-K-1 CTRP2 4.964 8.8158 3.6802 12.2361
NCI-H2126 CTRP2 4.9674 8.2901 3.9335 11.1957
NCI-H146 CTRP2 5.026 9.2513 3.5294 12.7077
HCC1588 CTRP2 5.039 7.2326 4.4914 8.7692
NCI-H1373 CTRP2 5.0696 7.333 4.4777 8.745
NCI-H292 CTRP2 5.0706 7.4129 4.4426 8.8831
LK2 CTRP2 5.1238 6.0702 5.0326 6.4528
HCC78 CTRP2 5.1621 8.0566 4.2335 9.5054
HOP-62 CTRP2 5.2041 12.765 1.9604 18.4902
NCI-H2170 CTRP2 5.2123 7.648 4.4753 8.3995
HCC1833 CTRP2 5.2146 12.2167 2.2421 17.4131
NCI-H1666 CTRP2 5.2403 8.5594 4.0669 10.0056
NCI-H1650 CTRP2 5.2983 9.7159 3.555 11.9877
HCC366 CTRP2 5.3257 8.1779 4.3323 8.7152
NCI-H2106 CTRP2 5.3576 10.6437 3.15 13.5187
NCI-H2085 CTRP2 5.4022 12.6393 2.1976 17.1755
COLO 699 CTRP2 5.4253 11.4561 2.8068 14.7566
SW1271 CTRP2 5.4291 7.8705 4.5788 7.4607
NCI-H1623 CTRP2 5.4415 7.3251 4.8516 6.313
Calu-6 CTRP2 5.447 7.9447 4.5598 7.4979
NCI-H1105 CTRP2 5.4984 9.3094 3.9372 9.968
HCC95 CTRP2 5.5365 8.0043 4.6146 7.0679
EPLC-272H CTRP2 5.5551 7.7999 4.7317 6.5407
NCI-H2228 CTRP2 5.575 8.0146 4.6452 6.8547
HCC1171 CTRP2 5.5819 12.2989 2.5238 15.5417
COR-L105 CTRP2 5.619 7.276 5.046 5.097
COR-L95 CTRP2 5.6289 8.311 4.5486 7.1379
NCI-H2029 CTRP2 5.6532 9.0605 4.1991 8.5454
DMS 273 CTRP2 5.6619 7.2714 5.0889 4.8212
NCI-H1651 CTRP2 5.6658 9.0571 4.212 8.4647
IA-LM CTRP2 5.6779 8.2536 4.6213 6.7289
NCI-H838 CTRP2 5.6871 9.0213 4.2486 8.2667
NCI-H2196 CTRP2 5.7084 9.5917 3.9835 9.3308
DMS 114 CTRP2 5.7614 8.9561 4.3465 7.7023
NCI-H358 CTRP2 5.7768 9.3201 4.1785 8.374
LUDLU-1 CTRP2 5.7911 8.8117 4.4444 7.2307
NCI-H1339 CTRP2 5.8029 7.0078 5.3491 3.4245
Sq-1 CTRP2 5.8081 12.9307 2.4024 15.5457
NCI-H1395 CTRP2 5.8119 8.8196 4.4586 7.1283
NCI-H1869 CTRP2 5.8165 8.8864 4.4292 7.2419
NCI-H2009 CTRP2 5.8306 7.92 4.923 5.1431
LCLC-97TM1 CTRP2 5.8579 7.4728 5.1694 4.0542
NCI-H226 CTRP2 5.8608 9.0155 4.4032 7.2608
NCI-H1915 CTRP2 5.8956 7.7427 5.0682 4.3998
NCI-H1838 CTRP2 5.8959 8.5246 4.6785 6.0343
Lu-65 CTRP2 5.9299 6.9839 5.4761 2.6192
NCI-H2122 CTRP2 5.9495 9.1528 4.4104 7.0532
NCI-H522 CTRP2 5.9567 9.6374 4.1743 8.0302
DMS 454 CTRP2 5.958 9.0044 4.4918 6.6945
NCI-H2444 CTRP2 5.9586 9.6649 4.1621 8.0775
NCI-H322 CTRP2 5.9673 7.4733 5.2647 3.4291
HCC2935 CTRP2 6.016 8.4343 4.8257 5.1778
LC-1/sq-SF CTRP2 6.0738 7.2888 5.4465 2.4572
HCC1438 CTRP2 6.0929 8.6449 4.7843 5.2037
NCI-H2405 CTRP2 6.1525 11.1816 3.5653 10.1932
NCI-H1693 CTRP2 6.1663 9.8784 4.228 7.4012
NCI-H1792 CTRP2 6.1847 9.9969 4.1839 7.5519
SBC-5 CTRP2 6.2495 8.1346 5.165 3.3192
NCI-H889 CTRP2 6.3487 19.9284 -0.6457 24.2211
KNS-62 CTRP2 6.3967 9.0946 4.802 4.5806
T3M-10 CTRP2 6.4136 8.7833 4.9691 3.8554
NCI-H520 CTRP2 6.4475 10.1999 4.2923 6.6213
BEN CTRP2 6.4673 8.3631 5.2158 2.7466
NCI-H2342 CTRP2 6.5041 11.334 3.7722 8.6867
SW1573 CTRP2 6.5195 19.5204 -0.3019 22.9946
NCI-H650 CTRP2 6.5297 11.6064 3.6567 9.1191
NCI-H460 CTRP2 6.6981 9.023 5.0584 3.0397
HCC4006 CTRP2 6.8028 9.5191 4.8913 3.5638
RERF-LC-Ad1 CTRP2 6.9661 8.0444 5.6681 0.4652
HCC1195 CTRP2 7.0483 13.3066 3.2122 10.0334
Calu-1 CTRP2 7.2975 15.1082 2.5097 12.3644
LCLC-103H CTRP2 7.3562 10.1181 4.9693 2.5265
NCI-H1299 CTRP2 7.5707 11.6151 4.4052 4.4392
NCI-H196 CTRP2 7.5776 13.166 3.6662 7.3709
MOR/CPR CTRP2 7.6767 8.5675 5.7598 0.0478
NCI-H1734 CTRP2 7.717 10.7124 4.913 2.335
HCC2108 CTRP2 7.8807 14.9654 3.0062 10.1754
HCC827 CTRP2 8.3139 12.5669 4.4241 3.7328
NCI-H2172 CTRP2 8.349 9.6954 5.6126 0.0939
NCI-H2030 CTRP2 8.4188 10.0615 5.5107 0.2189
NCI-H441 CTRP2 8.4457 13.0208 4.296 3.8019
NCI-H2291 CTRP2 8.703 19.0635 1.5954 13.4181
NCI-H1793 CTRP2 9.4034 19.3587 1.9357 11.2425
Hs 888.Lu CTRP2 4.8261 10.4879 2.7405 16.3519
⏷ Show the Full List of 142 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 0.5196 9.7347 -1.2796 40.6694
A2780 CTRP2 3.104 5.0704 3.0395 19.8081
COV434 CTRP2 3.7324 6.1591 3.489 16.2581
TYK-nu CTRP2 4.2102 6.686 3.8369 13.5655
ONCO-DG-1 CTRP2 4.316 7.5337 3.6146 14.1274
Caov-3 CTRP2 4.6147 7.7013 3.8506 12.4114
FU-OV-1 CTRP2 4.6832 9.1024 3.2726 14.5599
OVCAR-5 CTRP2 4.7008 8.477 3.5841 13.2609
SNU-119 CTRP2 4.8036 9.0546 3.4118 13.7084
OAW28 CTRP2 4.9689 8.8689 3.6595 12.309
MCAS CTRP2 5.0224 8.0903 4.0814 10.4613
IGROV-1 CTRP2 5.0344 7.6916 4.279 9.6316
OVK18 CTRP2 5.1659 7.5693 4.4662 8.5498
OVCAR-4 CTRP2 5.2135 7.9115 4.3522 8.8975
HEY A8 CTRP2 5.22 7.9361 4.3469 8.9038
OC 314 CTRP2 5.2248 8.2461 4.2033 9.4805
SNU-840 CTRP2 5.2776 9.6934 3.5471 12.0661
JHOM-1 CTRP2 5.4149 8.9632 4.0321 9.7559
OVTOKO CTRP2 5.4423 9.1037 3.9879 9.8793
TOV-21G CTRP2 5.4981 6.4952 5.2848 4.4329
Kuramochi CTRP2 5.545 9.3575 3.9552 9.7929
OV-90 CTRP2 5.5789 7.5477 4.8767 5.8872
OVSAHO CTRP2 5.5806 9.2622 4.0343 9.3872
ES2 CTRP2 5.6401 8.8685 4.2827 8.2239
JHOS-2 CTRP2 5.6864 8.297 4.6075 6.7682
SK-OV-3 CTRP2 5.7855 8.2673 4.7104 6.1278
DOV13 CTRP2 5.7945 8.5433 4.581 6.651
TOV-112D CTRP2 5.8278 9.5441 4.1109 8.5535
OAW42 CTRP2 5.9081 7.3453 5.2772 3.4978
SNU-8 CTRP2 5.9379 10.4868 3.7338 9.9093
COV644 CTRP2 5.9394 7.3053 5.3244 3.2353
OVCAR-8 CTRP2 5.9841 8.902 4.565 6.3356
OV7 CTRP2 6.0005 9.8152 4.1223 8.1621
EFO-27 CTRP2 6.0441 8.6245 4.7541 5.4242
OVISE CTRP2 6.1072 7.8071 5.2148 3.3676
RMG-I CTRP2 6.1202 10.7131 3.7729 9.3925
EFO-21 CTRP2 6.255 8.0518 5.2103 3.1198
COV362 CTRP2 6.3044 10.4344 4.0621 7.8402
OV56 CTRP2 6.5502 9.0752 4.9271 3.8059
JHOC-5 CTRP2 8.0358 9.2975 5.6375 0.1175
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 1.1704 6.3139 0.6492 34.0998
Yamato-SS CTRP2 1.201 6.1502 0.7293 33.7572
A-204 CTRP2 -0.6432 7.6689 -1.7544 45.8775
G-402 CTRP2 0.8801 9.2587 -0.7071 38.3868
Tm87-16 CTRP2 3.1072 7.3165 2.4198 22.0388
Rh41 CTRP2 3.4499 6.4223 3.1014 18.5196
KYM-1 CTRP2 3.8284 6.1171 3.6058 15.5444
G-401 CTRP2 3.8605 7.1115 3.3036 16.5764
TTC-709 CTRP2 3.9285 7.6814 3.1478 16.9857
GCT CTRP2 4.0718 6.7836 3.6526 14.6559
Rh18 CTRP2 4.5397 8.0943 3.5987 13.6062
TE 617.T CTRP2 4.8296 6.6058 4.532 9.1753
TE 441.T CTRP2 5.0784 7.4661 4.4264 8.9285
Hs 729.T CTRP2 5.2411 7.9849 4.344 8.8655
BT-12 CTRP2 5.3142 7.2839 4.7456 7.054
SK-LMS-1 CTRP2 5.4342 8.5428 4.2562 8.7831
BT-16 CTRP2 5.6241 8.5124 4.4447 7.5817
SW982 CTRP2 6.0091 7.7628 5.1556 3.8047
RD CTRP2 6.1165 7.3229 5.4642 2.303
HT-1080 CTRP2 6.4628 8.4562 5.1669 2.9549
RKN CTRP2 6.7271 10.1872 4.5107 5.242
SK-UT-1 CTRP2 7.1074 11.1592 4.3096 5.4761
MES-SA CTRP2 7.291 8.8612 5.4892 0.7668
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 4.6766 8.3751 3.6074 13.2269
H-STS CTRP2 4.957 7.1349 4.45 9.1469
P-STS CTRP2 5.2127 6.9367 4.7996 7.096
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 5.3644 19.1828 -1.0998 27.2824
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2 2.0773 8.3611 0.9185 30.2809
NCI-H28 CTRP2 3.1684 6.1589 2.8737 20.194
IST-Mes1 CTRP2 4.5303 7.1744 3.9888 12.0919
ACC-MESO-1 CTRP2 5.0833 8.0224 4.173 9.9414
MPP 89 CTRP2 5.5385 7.4812 4.8706 6.0059
NCI-H2452 CTRP2 5.5595 8.9316 4.1792 8.8283
JL-1 CTRP2 6.3255 8.879 4.854 4.4868
NCI-H2052 CTRP2 8.208 10.0302 5.4396 0.3924
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC CTRP2 4.6995 9.6514 3.0261 15.5108
22Rv1 CTRP2 4.9588 8.205 3.9652 11.0875
VCaP CTRP2 5.7804 8.1709 4.7538 5.9567
DU145 CTRP2 6.046 9.6203 4.2578 7.5057
PaCa-3 CTRP2 6.348 8.4089 5.1046 3.4015
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 6.69 8.5295 5.29 2.1201
YD-15 CTRP2 7.9274 9.0013 5.7004 0.0684
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-620 CTRP2 -2.6331 -1.3468 -2.6331 57.8108
Hs 746.T CTRP2 -0.2346 18.7918 -6.0995 46.671
SNU-16 CTRP2 1.8441 3.4276 1.8399 27.9971
HGC-27 CTRP2 3.4468 4.6323 3.4382 17.3344
GSS CTRP2 3.5431 5.0489 3.5084 16.781
SNU-216 CTRP2 4.2051 7.491 3.5167 14.8068
NCI-N87 CTRP2 4.3746 7.2343 3.8005 13.2458
IM95 CTRP2 4.5216 8.6944 3.3056 14.823
23132/87 CTRP2 4.5398 6.9127 4.1044 11.6191
NUGC-4 CTRP2 4.5564 12.0109 1.7455 20.7468
KATO III CTRP2 4.6014 9.1371 3.1765 15.1438
ECC10 CTRP2 4.684 6.6241 4.3691 10.2049
SNU-1 CTRP2 4.7568 7.7428 3.9767 11.5445
LMSU CTRP2 4.9413 14.3067 0.9614 22.5277
NUGC-3 CTRP2 4.9883 7.7248 4.2177 9.9933
SNU-601 CTRP2 5.3532 8.1261 4.3833 8.4415
MKN74 CTRP2 5.5561 8.4882 4.395 7.9369
MKN7 CTRP2 5.5733 7.9677 4.6666 6.7697
HuG1-N CTRP2 5.7947 14.3272 1.6931 18.2059
SH-10-TC CTRP2 5.9231 8.0036 4.962 4.7895
GSU CTRP2 6.0839 7.2293 5.4846 2.278
MKN45 CTRP2 6.186 15.4295 1.4693 18.2046
ECC12 CTRP2 6.3434 8.9044 4.8553 4.4501
KE-39 CTRP2 6.6288 10.4858 4.29 6.3189
MKN1 CTRP2 6.8055 9.5793 4.864 3.671
SNU-668 CTRP2 7.7388 10.0332 5.2223 1.2533
AGS CTRP2 7.7956 9.6089 5.4244 0.622
SNU-719 CTRP2 8.0594 10.0921 5.3522 0.6612
Fu97 CTRP2 8.1611 9.6933 5.5445 0.218
SNU-1077 CTRP2 4.0852 7.9658 3.1905 16.3991
SNG-M CTRP2 5.3882 8.1362 4.4115 8.2449
SNU-685 CTRP2 5.7991 7.6483 5.0298 4.763
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CGTH-W-1 CTRP2 1.0126 8.8781 -0.416 37.3278
SW579 CTRP2 2.0825 11.3437 -0.3509 33.6836
B-CPAP CTRP2 4.2025 6.048 4.0333 12.8632
FTC-238 CTRP2 4.3468 7.3054 3.742 13.5481
8505C CTRP2 4.7843 7.9196 3.9243 11.6845
8305C CTRP2 5.0973 7.5508 4.4065 8.9612
ML-1 [Human leukemia] CTRP2 5.2028 7.1041 4.7155 7.4557
TT CTRP2 5.4592 12.205 2.4638 16.034
TT2609-C02 CTRP2 6.1245 8.1124 5.0763 3.9172
CAL-62 CTRP2 6.3283 9.0687 4.7618 4.8673
FTC-133 CTRP2 6.4466 10.0094 4.3863 6.2299
BHT-101 CTRP2 8.4233 9.9648 5.5464 0.1548
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BICR 18 CTRP2 3.4638 8.4178 2.3529 21.2838
YD-8 CTRP2 4.6889 6.3696 4.4651 9.8302
SCC-25 CTRP2 4.9765 7.3049 4.3956 9.3111
CAL-27 CTRP2 5.07 7.8153 4.257 9.6325
HSC-4 CTRP2 5.2447 8.6433 4.0303 10.1462
CAL-33 CTRP2 5.593 7.753 4.7899 6.2144
BICR 31 CTRP2 5.6176 7.8685 4.7562 6.2992
PE/CA-PJ15 CTRP2 5.6807 9.0274 4.2399 8.3167
SNU-1066 CTRP2 5.8399 9.4422 4.1722 8.2719
BICR 22 CTRP2 5.9371 6.743 5.602 2.0774
SNU-1076 CTRP2 6.0212 11.2853 3.4046 11.1104
BICR 16 CTRP2 6.196 12.1306 3.1267 11.9092
PE/CA-PJ34 (clone C12) CTRP2 6.2418 9.4892 4.4836 6.1893
SNU-1041 CTRP2 6.264 11.2625 3.616 9.7727
PE/CA-PJ49 CTRP2 6.2894 9.0192 4.7559 4.9612
HSC-2 CTRP2 6.292 10.2522 4.1431 7.5243
SCC-9 CTRP2 6.353 10.2541 4.1909 7.2132
BICR 6 CTRP2 6.4006 10.1863 4.2623 6.8296
BHY CTRP2 6.4455 9.7849 4.497 5.7699
FaDu CTRP2 6.4559 10.5848 4.1074 7.3782
PE/CA-PJ41 (clone D2) CTRP2 7.2477 11.0273 4.4704 4.6212
HSC-3 CTRP2 7.4073 8.7795 5.5772 0.4446
SNU-1214 CTRP2 7.6341 13.7512 3.422 8.259
SCC-4 CTRP2 7.7419 10.1261 5.1843 1.3734
SNU-46 CTRP2 8.2966 10.0959 5.451 0.338
BICR 56 CTRP2 8.3392 17.1887 2.2496 11.666
SNU-899 CTRP2 8.3596 10.1739 5.4474 0.3236
Detroit 562 CTRP2 8.8608 20.2245 1.1424 14.6825
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JMSU-1 CTRP2 2.8193 4.5977 2.7897 21.5854
U-BLC1 CTRP2 3.2305 6.3542 2.8836 19.9707
RT-112 CTRP2 3.3145 6.6659 2.8749 19.7534
RT-4 CTRP2 3.8168 7.6944 3.0252 17.762
5637 CTRP2 4.528 7.7617 3.7352 13.094
VM-CUB-1 CTRP2 4.5928 8.1775 3.6145 13.408
253J CTRP2 4.5937 5.7745 4.5259 9.8976
SW1710 CTRP2 4.9925 7.6087 4.2751 9.7521
UM-UC-3 CTRP2 5.1563 7.8708 4.3158 9.1837
HT-1376 CTRP2 5.3318 8.7669 4.0516 9.8602
647V CTRP2 5.521 7.7271 4.7351 6.6047
BFTC-905 CTRP2 5.5818 7.5449 4.8808 5.8638
J82 CTRP2 5.6155 8.0717 4.6543 6.7273
TCCSUP CTRP2 5.8081 10.0316 3.8507 9.6815
T24 CTRP2 6.1502 10.553 3.8776 8.8986
BC-3C CTRP2 6.163 8.6732 4.8275 4.8905
UM-UC-1 CTRP2 6.1922 11.0055 3.6859 9.6174
639V CTRP2 6.2429 8.8917 4.7826 4.933
KU-19-19 CTRP2 6.3288 9.3239 4.6352 5.3968
CAL-29 CTRP2 6.3359 8.452 5.074 3.5498
SCaBER CTRP2 6.4462 9.8786 4.451 5.9608
HT-1197 CTRP2 6.6799 10.9337 4.1071 6.9921
KMBC-2 CTRP2 6.8238 10.0063 4.6695 4.4371
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 6.1309 8.1152 5.0801 3.8894

References

1 ClinicalTrials.gov (NCT02544633) Phase 2 Study of MGCD265 in Patients With Non-Small Cell Lung Cancer With Activating Genetic Alterations in MET.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Company report (Mirati Therapeutics: formerly MethylGene)