Details of the Drug

General Information of Drug (ID: DMRSNEU)

Drug Name
Masitinib
Synonyms
Masitinib; 790299-79-5; AB1010; Masatinib; Masitinib (AB1010); Masivet; AB-1010; AB 1010; UNII-M59NC4E26P; Masitinib [INN]; M59NC4E26P; 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide; CHEMBL1908391; CHEBI:63450; Masitinib (INN); N-(4-Methyl-3-((4-(pyridin-3-yl)thiazol-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide; Q-201339; C28H30N6OS; N-(4-methyl-3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide
Indication
Disease Entry ICD 11 Status REF
Amyotrophic lateral sclerosis 8B60.0 Phase 3 [1]
Gastrointestinal stromal tumour 2B5B Phase 3 [2]
Metastatic gastric or gastroesophageal junction cancer 2D8Y Phase 3 [1]
Multiple sclerosis 8A40 Phase 3 [3]
Ovarian cancer 2C73 Phase 3 [2]
Pancreatic cancer 2C10 Phase 3 [2]
⏷ Show the Full List of Indication(s)
ATC Code
L01EX06: Masitinib
L01EX: Other protein kinase inhibitors
L01E: PROTEIN KINASE INHIBITORS
L01: ANTINEOPLASTIC AGENTS
L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 498.6
Logarithm of the Partition Coefficient (xlogp) 4.3
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C28H30N6OS
IUPAC Name
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide
Canonical SMILES
CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5
InChI
InChI=1S/C28H30N6OS/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3-11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34/h3-11,16-17,19H,12-15,18H2,1-2H3,(H,30,35)(H,31,32)
InChIKey
WJEOLQLKVOPQFV-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
10074640
ChEBI ID
CHEBI:63450
CAS Number
790299-79-5
UNII
M59NC4E26P
DrugBank ID
DB11526
TTD ID
D0MW0N
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Proto-oncogene c-Src (SRC) TT6PKBN SRC_HUMAN Inhibitor [3]
Tyrosine-protein kinase (PTK) TTJSQEF NOUNIPROTAC Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Cytochrome P450 2C8 (CYP2C8) OTHCWT42 CP2C8_HUMAN Regulation of Drug Effects [4]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Regulation of Drug Effects [4]
Fibroblast growth factor receptor 3 (FGFR3) OTSAXDIL FGFR3_HUMAN Gene/Protein Processing [5]
Platelet-derived growth factor receptor alpha (PDGFRA) OTDJXUCN PGFRA_HUMAN Gene/Protein Processing [5]
Platelet-derived growth factor receptor beta (PDGFRB) OTYSNK9Q PGFRB_HUMAN Gene/Protein Processing [5]
Transforming growth factor beta-1 proprotein (TGFB1) OTV5XHVH TGFB1_HUMAN Protein Interaction/Cellular Processes [6]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Protein Interaction/Cellular Processes [5]
Tyrosine-protein kinase Lyn (LYN) OTP686K2 LYN_HUMAN Gene/Protein Processing [5]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Amyotrophic lateral sclerosis
ICD Disease Classification 8B60.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Proto-oncogene c-Src (SRC) DTT SRC 6.45E-01 -0.08 -0.58
Proto-oncogene c-Src (SRC) DTT SRC 2.08E-03 -0.52 -1.62
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 3.6234 5.2773 3.1849 11.8653
ES7 GDSC1 1.331 4.4491 1.0222 38.9092
ES1 GDSC1 2.0917 3.0569 2.0862 27.9122
SJSA-1 GDSC1; CTRP2 2.7062 5.5377 2.3427 18.0764
ES5 GDSC1 3.0634 4.6885 2.8334 17.2789
EW-13 GDSC1 3.2636 6.4503 2.2846 20.2105
SK-N-MC CTRP2 3.5846 5.0465 3.5524 16.496
EW-1 GDSC1 3.6046 5.2901 3.1601 12.1414
EW-7 GDSC1 3.6477 4.543 3.5158 9.3185
EW-18 GDSC1 3.6764 4.5715 3.5364 9.0185
MHH-ES-1 GDSC1; CTRP2 3.6854 4.8277 3.6143 9.9627
ES6 GDSC1 3.7322 4.9526 3.4401 9.4343
ES8 GDSC1 3.7553 4.5804 3.6178 8.0202
SK-PN-DW GDSC1 3.7868 4.6477 3.6252 7.8024
TC-71 GDSC1 3.8255 4.6803 3.6529 7.4032
A-673 GDSC1; CTRP2 3.827 4.9614 3.8132 14.8189
EW-16 GDSC1 3.8395 4.8203 3.6082 7.6611
ES4 GDSC1 3.8874 5.3362 3.419 8.8686
NOS-1 [Human HNSCC] GDSC1 3.8878 15.3904 -1.5781 34.2792
EW-11 GDSC1 3.902 5.5668 3.3224 9.5476
CADO-ES1 GDSC1 4.057 5.0266 3.7302 5.7244
SK-ES-1 GDSC1; CTRP2 4.0571 5.3219 4.0217 13.3594
EW-3 GDSC1 4.0753 5.3408 3.5947 6.6957
SW1353 CTRP2 4.0975 5.0075 4.09 12.9955
Hs 888.T CTRP2 4.1269 5.3568 4.0916 12.8939
EW-24 GDSC1 4.2342 4.9581 3.9281 3.4388
TC71 CTRP2 4.4242 6.3233 4.1928 11.6161
Hs 822.T CTRP2 4.4369 4.9218 4.4366 10.71
HOS GDSC1; CTRP2 4.5955 9.9483 2.784 16.7218
HuO-3N1 GDSC1 4.6655 12.3263 0.6023 24.3047
SaOS-2 GDSC1; CTRP2 4.6778 5.6946 4.6318 9.2615
U2OS GDSC1; CTRP2 4.8638 9.7614 2.5338 11.6533
CHSA0108 GDSC1 5.0289 7.4931 3.2798 5.9782
CAL-78 GDSC1; CTRP2 5.0415 6.1491 4.9196 7.112
MG-63 GDSC1; CTRP2 5.0857 6.0152 5.006 6.6647
G-292 clone A141B1 GDSC1; CTRP2 5.1616 6.3784 4.9728 6.5636
CHSA8926 GDSC1 5.9921 7.909 3.6552 1.4996
H-EMC-SS GDSC1 6.1174 8.6727 3.3978 2.8104
CAL-72 GDSC1 6.7712 8.2756 3.8378 0.236
CHSA0011 GDSC1 6.9542 12.3759 2.2198 8.7099
NY GDSC1 7.3347 9.4338 3.6396 0.4991
HuO9 GDSC1 7.4805 27.1872 -4.5969 31.3069
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 208 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -2.0006 3.7139 -2.2264 53.2144
MEC1 CTRP2 3.8656 6.3954 3.5623 15.5919
JM1 GDSC1; CTRP2 4.0045 5.8236 3.8743 14.0407
EoL-1 GDSC1; CTRP2 -10.4532 -8.3239 -10.4532 98.7401
MEG-01 GDSC1 -2.5036 0.6322 -2.5273 78.9732
LAMA-84 GDSC1; CTRP2 -2.037 0.359 -2.0403 50.5431
GDM-1 GDSC1; CTRP2 -1.5853 2.2089 -1.6264 50.8086
JURL-MK1 GDSC1; CTRP2 -1.1568 1.1719 -1.1591 47.9787
NCO2 CTRP2 -1.0181 1.2207 -1.0201 47.0553
ALL-SIL GDSC1; CTRP2 -0.9779 1.1753 -0.9794 46.7865
K-562 GDSC1; CTRP2 -0.864 3.9106 -1.0378 46.2713
Ku812 GDSC1; CTRP2 -0.4174 1.504 -0.4184 43.0524
EM-2 GDSC1; CTRP2 -0.3079 3.1351 -0.3614 42.458
Kasumi-1 GDSC1; CTRP2 -0.14 5.1478 -0.4829 41.9797
BV-173 GDSC1; CTRP2 0.1349 3.9574 0.0222 39.6897
MOLM-6 CTRP2 0.2125 3.3841 0.1626 39.0039
CML-T1 CTRP2 0.2765 2.642 0.2664 38.4587
KYO-1 CTRP2 0.602 1.6606 0.602 36.2582
EB2 GDSC1 0.6916 8.1105 -1.0651 47.5454
DEL GDSC1; CTRP2 0.7246 1.8847 0.7245 35.4416
SR GDSC1; CTRP2 0.7891 1.8709 0.7891 35.0117
DND-41 GDSC1 1.1179 3.2249 1.0523 40.3867
CTV-1 GDSC1 1.434 5.9912 0.5972 39.7372
Peer CTRP2 1.4632 4.115 1.4102 30.6978
JSC-1 GDSC1 1.7546 4.0376 1.5923 33.076
GR-ST GDSC1 1.7821 3.7028 1.6913 32.3093
Pfeiffer CTRP2 1.8259 5.5992 1.5541 29.0242
Karpas-231 GDSC1 1.8393 3.848 1.7257 31.7377
KG-1 GDSC1 1.9111 4.7236 1.5712 32.1985
CESS GDSC1 1.9166 3.159 1.9008 30.166
Sc-1 GDSC1 2.0828 3.911 1.977 28.6614
SUP-B15 GDSC1; CTRP2 2.0871 6.0881 1.7137 27.6435
THP-1 GDSC1; CTRP2 2.1122 4.4689 2.0586 26.3774
KCL-22 GDSC1; CTRP2 2.1228 4.1437 2.0973 26.2118
NALM-6 GDSC1; CTRP2 2.1864 5.0752 1.9169 21.4085
MOLT-13 GDSC1; CTRP2 2.3025 3.7079 2.2988 24.9412
KOPN-8 GDSC1 2.3049 3.811 2.2362 25.6516
EB1 CTRP2 2.3496 6.5007 1.8789 26.249
VAL GDSC1 2.5005 4.4765 2.2899 24.1495
P32/ISH GDSC1 2.6077 4.5142 2.3953 22.8281
LP-1 GDSC1; CTRP2 2.715 4.9429 2.6417 22.4295
NU-DUL-1 GDSC1; CTRP2 2.8443 4.5745 2.8177 21.4086
SU-DHL-16 GDSC1 2.9262 4.3634 2.7872 18.3616
Mono-Mac-6 GDSC1 2.9276 4.7133 2.6779 19.1063
GA-10 CTRP2 2.9538 6.3139 2.5943 21.8536
MOLM-16 CTRP2 2.973 5.8631 2.7402 21.271
MOTN-1 CTRP2 2.9994 5.5142 2.8496 20.8012
Daudi GDSC1; CTRP2 3.0566 4.4202 3.0467 19.9383
KMS-12-BM GDSC1; CTRP2 3.0719 4.5355 3.0567 19.8541
JVM-2 GDSC1 3.1091 8.7345 1.0382 28.4696
WSU-DLCL2 GDSC1; CTRP2 3.1233 4.2488 3.1199 19.472
TALL-1 [Human adult T-ALL] CTRP2 3.2215 5.1266 3.1571 19.025
RPMI-8402 GDSC1; CTRP2 3.2595 4.6281 3.2454 18.6009
HAL-01 GDSC1 3.3203 4.2549 3.2463 13.0028
KHM-1B CTRP2 3.3297 5.3038 3.0963 13.126
KM-H2 GDSC1; CTRP2 3.3414 4.2646 3.3271 12.207
Ri-1 CTRP2 3.3441 6.341 3.0114 19.1644
Hs 611.T CTRP2 3.3765 5.4644 3.2682 18.1449
NU-DHL-1 CTRP2 3.3847 4.6344 3.3742 17.7545
KE-37 GDSC1; CTRP2 3.4132 4.1702 3.4129 17.5305
QIMR-WIL GDSC1 3.45 5.0706 3.0972 13.3645
TUR GDSC1 3.4782 7.3468 2.0594 20.779
BL-41 GDSC1 3.5105 4.3662 3.4239 10.7145
PF-382 GDSC1; CTRP2 3.5196 4.6504 3.512 16.8458
P30/OHK GDSC1 3.5417 7.2097 2.1855 19.6311
HC-1 GDSC1 3.5446 4.4211 3.4446 10.3803
Karpas-422 GDSC1; CTRP2 3.5492 5.4951 3.4492 16.9658
Karpas-620 GDSC1; CTRP2 3.5519 8.7567 2.2973 21.2517
MOLM-13 GDSC1; CTRP2 3.555 6.7615 3.1028 18.2057
RL GDSC1; CTRP2 3.5552 5.0295 3.5232 16.6912
SCC-3 GDSC1 3.5586 4.2629 3.5042 9.8964
Ki-JK CTRP2 3.5604 4.6749 3.5528 16.5742
SUP-M2 GDSC1 3.5757 4.1495 3.5473 9.5099
KMS-21-BM CTRP2 3.5808 6.0622 3.3509 17.2173
697 GDSC1 3.589 4.8414 3.3382 10.8998
CA46 GDSC1 3.5968 8.0069 1.845 21.6691
SU-DHL-4 GDSC1; CTRP2 3.6028 4.9602 3.5795 16.3444
KMS-28BM CTRP2 3.6108 5.8636 3.4357 16.821
KMS-20 CTRP2 3.6127 4.9732 3.5888 16.2809
LC4-1 GDSC1 3.6158 9.3972 1.1742 25.5115
BALL-1 GDSC1 3.6272 5.6458 3.0189 13.0997
KMS-11 GDSC1; CTRP2 3.6286 5.041 3.5992 16.1934
KMS-34 CTRP2 3.6309 5.4514 3.5454 16.3712
MOLT-16 GDSC1; CTRP2 3.6364 5.0661 3.605 16.1481
ML-2 GDSC1 3.6384 4.5118 3.5167 9.3628
NKM-1 GDSC1 3.6434 11.9948 -0.0936 30.8998
BE-13 GDSC1 3.6475 11.8725 -0.0292 30.6547
MLMA GDSC1 3.6535 8.9386 1.4354 23.9135
RPMI-8866 GDSC1 3.6632 7.2069 2.2994 18.2968
OCI-AML-5 GDSC1; CTRP2 3.6894 4.1852 3.6893 15.6896
SU-DHL-5 GDSC1 3.6908 4.1489 3.6715 8.012
BC-1 GDSC1 3.693 7.2002 2.3301 17.9493
Jurkat CTRP2 3.6965 5.5268 3.4182 10.6965
SET-2 CTRP2 3.7012 6.5237 3.3419 16.8904
HuT 78 CTRP2 3.7024 6.1187 3.4678 16.4258
MM1.S CTRP2 3.7043 5.4454 3.6257 15.8584
Ramos.2G6.4C10 GDSC1 3.7071 5.4579 3.1854 11.4692
SU-DHL-1 GDSC1; CTRP2 3.7078 4.0491 3.7078 15.5665
CCRF-CEM GDSC1 3.7095 4.3796 3.637 8.1353
HH [Human lymphoma] GDSC1 3.715 5.3887 3.2254 11.1292
OPM-2 GDSC1; CTRP2 3.7155 5.3258 3.6568 15.7151
DB GDSC1; CTRP2 3.7192 5.3825 3.6521 15.7195
ST486 GDSC1; CTRP2 3.7359 5.4307 3.6622 15.631
HEL GDSC1; CTRP2 3.7427 4.6905 3.7024 9.4382
AML-193 CTRP2 3.7467 4.6293 3.7441 15.3164
ARH-77 GDSC1 3.7469 4.4555 3.6534 7.8142
M-07e CTRP2 3.7476 4.7659 3.7411 15.3232
WIL2 NS GDSC1 3.7646 4.3509 3.7056 7.3559
KMOE-2 GDSC1 3.7657 4.5754 3.6308 7.8732
MOLT-4 GDSC1 3.7704 4.6161 3.6202 7.924
PL-21 GDSC1 3.78 5.0904 3.4274 9.2993
F-36P CTRP2 3.7844 5.7472 3.6524 15.5123
ATN-1 GDSC1 3.7887 4.3289 3.7381 6.9977
KE-97 CTRP2 3.7894 5.3016 3.5968 9.6929
MN-60 GDSC1 3.7903 4.9673 3.4932 8.7564
CTB-1 GDSC1 3.7906 5.6969 3.1535 11.3362
A3/Kawakami GDSC1 3.7911 4.1951 3.7716 6.7606
ROS-50 GDSC1 3.794 4.7073 3.6087 7.8851
Hs 445 GDSC1 3.8043 4.3894 3.7372 6.9161
SUP-T11 CTRP2 3.8044 4.9527 3.7902 14.9706
Karpas-299 GDSC1; CTRP2 3.8048 4.456 3.8045 14.9216
DG-75 GDSC1 3.8115 4.6737 3.6408 7.5622
VL51 GDSC1 3.8156 4.7363 3.6193 7.6985
P12-Ichikawa GDSC1; CTRP2 3.8177 5.3527 3.7623 15.0227
Loucy GDSC1 3.8206 4.384 3.7567 6.6908
SU-DHL-6 GDSC1; CTRP2 3.8209 5.4429 3.7516 15.0495
ALL-PO GDSC1 3.8216 5.249 3.3958 9.3435
MHH-PREB-1 GDSC1 3.8322 4.3857 3.7688 6.5429
KMS-26 CTRP2 3.8362 4.4148 3.8361 14.7116
TK [Human B-cell lymphoma] GDSC1 3.8423 4.4515 3.7582 6.5603
YT GDSC1 3.8523 4.3564 3.7996 6.2188
MOLP-8 GDSC1; CTRP2 3.8525 5.5133 3.7735 14.8728
SUP-T1 GDSC1; CTRP2 3.8595 4.9182 3.8493 14.5901
RPMI-8226 GDSC1; CTRP2 3.8723 5.1826 3.8418 14.5737
Farage GDSC1 3.8726 4.5242 3.7645 6.3533
Namalwa GDSC1 3.8814 4.9473 3.5945 7.5615
WSU-NHL GDSC1 3.8871 4.5 3.7891 6.1017
KMS-18 CTRP2 3.9601 5.3676 3.9124 14.0477
A4/Fukuda GDSC1; CTRP2 3.9712 5.0481 3.9571 13.859
L-363 GDSC1; CTRP2 3.9755 5.9125 3.8212 14.3199
HT GDSC1; CTRP2 3.9794 4.4108 3.9794 13.7576
KY821 GDSC1 3.9853 4.741 3.7926 5.5789
Reh GDSC1; CTRP2 3.9974 5.0631 3.9833 13.6848
U-698-M GDSC1 4.0004 4.7834 3.7887 5.5356
KMM-1 CTRP2 4.0101 7.8748 3.1517 16.7503
SU-DHL-8 GDSC1; CTRP2 4.0139 5.844 3.8798 13.992
JVM-3 GDSC1; CTRP2 4.022 5.9775 3.8552 14.0551
RCH-ACV CTRP2 4.0224 5.9403 3.8653 14.0175
OCI-AML-2 GDSC1; CTRP2 4.026 4.9195 4.0204 13.4656
KMS-27 CTRP2 4.0347 5.5724 3.9597 13.6456
SK-MM-2 GDSC1; CTRP2 4.0351 5.5868 3.9575 13.6517
SU-DHL-10 GDSC1; CTRP2 4.0501 5.5003 3.9887 13.4956
Jiyoye GDSC1 4.0561 5.0538 3.7163 5.8348
RS4;11 GDSC1; CTRP2 4.0704 5.4743 3.8394 7.8506
JeKo-1 CTRP2 4.0967 6.6271 3.7354 14.2731
HPB-ALL CTRP2 4.1093 5.9515 3.9572 13.4216
MC116 GDSC1; CTRP2 4.1633 4.9694 4.159 12.5464
Raji GDSC1; CTRP2 4.1657 4.8745 4.1638 12.5226
P31/FUJ GDSC1; CTRP2 4.1987 4.9163 4.1964 12.3038
L-540 GDSC1; CTRP2 4.2169 5.1216 4.2073 12.2075
H9 GDSC1 4.2196 5.7228 3.5345 6.5912
SEM CTRP2 4.2238 5.008 4.2195 12.1435
Karpas-45 GDSC1 4.2539 10.8004 1.0258 23.7299
Kasumi-2 CTRP2 4.2622 5.2587 4.2447 11.9319
JJN-3 GDSC1; CTRP2 4.2693 5.4454 4.2318 11.9531
U-937 CTRP2 4.2714 5.6588 4.1995 12.0583
U266B1 GDSC1; CTRP2 4.279 5.409 4.2468 11.8701
EHEB CTRP2 4.3111 5.7739 4.2193 11.8638
NOMO-1 GDSC1; CTRP2 4.3167 5.2901 4.2991 11.5694
AMO1 GDSC1; CTRP2 4.3176 6.215 4.1107 12.2346
PL21 CTRP2 4.325 5.5553 4.2754 11.6238
NCI-H929 CTRP2 4.3821 5.2951 4.3672 11.1245
Mino CTRP2 4.388 5.4591 4.3564 11.1421
MV4-11 GDSC1; CTRP2 4.3957 5.7988 4.3058 11.2937
OCI-AML-3 GDSC1; CTRP2 4.4073 5.7201 4.3347 11.1559
BL-70 CTRP2 4.4152 5.875 4.3097 11.2192
HuNS1 CTRP2 4.4297 6.3299 4.1967 11.5856
HDLM-2 GDSC1; CTRP2 4.4402 5.9315 4.3232 11.0938
L-428 GDSC1; CTRP2 4.4511 5.2157 4.444 10.6384
SKM-1 CTRP2 4.5264 5.1064 4.5248 10.1185
NB4 GDSC1; CTRP2 4.5874 4.9709 4.5873 9.707
Mono-Mac-1 CTRP2 4.7709 6.3121 4.5732 9.189
L-1236 GDSC1 4.8026 7.0313 3.344 6.1339
MOLP-2 CTRP2 4.8606 7.9944 3.9662 11.3249
MY-M12 GDSC1 4.8711 8.9874 2.4296 12.807
KO52 CTRP2 4.9093 5.9057 4.8405 7.7999
HD-MY-Z CTRP2 4.9142 7.4265 4.2781 9.9395
TF-1 CTRP2 4.9238 7.9988 4.027 10.9229
SUP-HD1 GDSC1; CTRP2 4.9362 6.5932 4.6507 8.4234
OCI-Ly10 CTRP2 4.9422 7.3614 4.3355 9.6387
MHH-CALL-4 CTRP2 5.0336 6.3898 4.8308 7.4649
Granta-519 GDSC1; CTRP2 5.0489 6.8962 4.6475 8.1274
OCI-Ly19 GDSC1; CTRP2 5.1105 6.7457 4.7747 7.4654
HL-60 GDSC1; CTRP2 5.1225 6.5262 4.8753 7.0445
OCI-Ly3 CTRP2 5.1332 6.3295 4.9598 6.6939
RPMI-6666 GDSC1; CTRP2 5.1395 11.0454 2.7548 15.5851
EJM GDSC1; CTRP2 5.1713 6.3833 4.9814 6.5035
MHH-CALL-3 CTRP2 5.3234 6.3221 5.1674 5.3674
CMK CTRP2 5.3803 5.9019 5.353 4.5179
BC-3 GDSC1 5.4031 11.8385 1.4222 17.6275
OCI-M1 GDSC1; CTRP2 5.4181 6.0202 5.3673 4.3495
SIG-M5 GDSC1; CTRP2 5.4332 5.8832 5.4135 4.1391
ME1 CTRP2 5.4583 6.0531 5.4024 4.1005
ME1 GDSC1 5.5605 6.9558 3.8381 1.0554
REC-1 CTRP2 5.8308 8.6183 4.5754 6.5999
P3HR-1 CTRP2 5.8879 14.3672 1.7519 17.8055
RC-K8 GDSC1 5.9622 7.6479 3.7462 1.0686
HEL 92.1.7 CTRP2 6.6751 12.9524 3.1009 11.128
⏷ Show the Full List of 208 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 4.6595 6.1322 4.5082 9.7589
TE15 CTRP2 5.124 8.9687 3.7588 11.5412
KYSE-270 GDSC1 3.8092 4.916 3.5352 8.3521
OE33 GDSC1 3.9793 4.7506 3.7821 5.6861
T.T GDSC1 3.9947 4.6987 3.8209 5.3226
TE-15 GDSC1 4.189 7.2502 2.7456 12.8599
OE21 GDSC1; CTRP2 4.2053 5.6806 4.1236 12.5327
TE-10 GDSC1; CTRP2 4.2448 5.3897 4.2128 12.0973
TE-6 GDSC1; CTRP2 4.2895 5.4899 4.0671 6.262
KYSE-410 GDSC1; CTRP2 4.3297 6.1911 4.1311 12.1237
TE-4 GDSC1; CTRP2 4.3674 6.4958 4.0738 12.2242
KYSE-180 GDSC1; CTRP2 4.4413 5.286 4.3074 4.8242
TE-9 GDSC1; CTRP2 4.4825 5.6228 4.4337 10.5722
KYSE-70 GDSC1; CTRP2 4.5318 5.3193 4.5214 10.1122
KYSE-140 GDSC1; CTRP2 4.5509 6.5062 3.8703 6.4048
KYSE-30 CTRP2 4.6613 6.4668 4.4017 10.147
TE-8 GDSC1 4.7127 6.7512 3.4156 5.8496
TE-14 CTRP2 4.7413 6.0537 4.6197 9.1072
TE-1 GDSC1; CTRP2 4.8484 5.9898 4.7536 8.2979
TE-5 GDSC1; CTRP2 4.8678 5.8975 4.7973 8.0822
EC-GI-10 GDSC1; CTRP2 5.1194 6.2243 4.9806 6.6568
KYSE-520 GDSC1; CTRP2 5.1625 6.427 4.9559 6.6249
TE-11 GDSC1; CTRP2 5.2293 6.763 4.8916 6.69
OE19 GDSC1; CTRP2 5.2954 6.3765 5.1172 5.6367
KYSE-510 GDSC1; CTRP2 5.34 6.294 5.1955 5.214
KYSE-150 GDSC1; CTRP2 5.3754 6.1342 5.2879 4.7666
KYSE-450 GDSC1; CTRP2 5.415 5.8942 5.3919 4.2722
COLO 680N GDSC1; CTRP2 5.6086 7.1039 5.1187 4.8226
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 5.3698 8.4561 4.2387 9.0002
HuP-T4 GDSC1; CTRP2 3.7399 4.8702 3.7284 15.3914
BxPC-3 GDSC1; CTRP2 3.7462 5.3939 3.6793 15.5385
MZ-PC-1 GDSC1 3.756 5.472 3.2269 10.93
Panc 10.05 GDSC1; CTRP2 4.0225 5.1022 4.0067 13.5232
SNU-213 CTRP2 4.0282 5.1428 4.0095 13.4951
MIA PaCa-2 GDSC1; CTRP2 4.0548 5.4084 4.0079 13.414
HPAC GDSC1; CTRP2 4.2229 5.4586 4.1804 12.2794
CFPAC-1 GDSC1; CTRP2 4.2296 5.5312 4.1767 12.2707
SU.86.86 GDSC1; CTRP2 4.257 5.1868 4.2448 11.9488
Panc 08.13 GDSC1; CTRP2 4.324 5.8988 4.2045 11.8763
PK-59 CTRP2 4.4706 5.9862 4.3424 10.932
YAPC GDSC1; CTRP2 4.5398 5.2388 4.5342 10.0427
Hs 766T GDSC1; CTRP2 4.5419 5.4343 4.5223 10.0759
Panc 05.04 CTRP2 4.5723 5.2359 4.5677 9.8229
Panc 03.27 GDSC1; CTRP2 4.5749 6.0392 4.4421 10.2542
Capan-2 GDSC1; CTRP2 4.5786 5.7455 4.5153 9.9824
KP-3 GDSC1; CTRP2 4.6196 5.69 4.3235 4.247
QGP-1 GDSC1; CTRP2 4.7571 5.8847 4.6797 8.8436
KP-4 GDSC1; CTRP2 4.7691 5.8906 4.6914 8.7646
Capan-1 GDSC1 4.7877 6.6374 3.5257 4.7801
HPAF-II GDSC1; CTRP2 4.8798 6.1387 4.7465 8.2286
PaTu 8988s CTRP2 4.9765 5.7524 4.9437 7.2262
TCC-Pan2 CTRP2 5.0031 6.0163 4.9155 7.2427
SNU-410 CTRP2 5.0261 9.6338 3.3436 13.4662
DAN-G GDSC1; CTRP2 5.0411 9.0827 3.6253 12.28
SW1990 GDSC1; CTRP2 5.1356 7.1701 4.6177 8.0177
Panc 02.03 GDSC1; CTRP2 5.1846 6.0288 5.1103 5.9876
PaTu 8902 GDSC1; CTRP2 5.2072 6.1901 5.0872 6.0042
AsPC-1 GDSC1; CTRP2 5.2338 6.1086 5.1414 5.7258
Panc 04.03 GDSC1; CTRP2 5.2566 5.9454 5.2095 5.411
PSN1 GDSC1; CTRP2 5.3463 6.5465 5.1044 5.545
PK-45H CTRP2 5.3581 6.3235 5.2042 5.1297
KP-2 GDSC1; CTRP2 5.3938 9.1215 3.9349 10.2059
L3.3 CTRP2 5.4659 8.9732 4.0738 9.4706
SUIT-2 GDSC1; CTRP2 5.492 6.8632 5.1165 5.1165
HuP-T3 GDSC1; CTRP2 5.5004 6.1223 5.4277 3.8817
PaTu 8988t GDSC1; CTRP2 5.5765 21.2054 -1.9295 28.6626
PL4 GDSC1 6.461 8.5623 3.6093 1.2128
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 75 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 4.3137 5.75 4.2271 13.6656
MZ-MEL-2 GDSC1 2.1934 4.8072 1.8505 28.7969
HMV-II GDSC1 2.6979 4.9117 2.3596 22.5684
WM35 GDSC1 2.8727 3.7389 2.8532 18.2386
COLO 792 GDSC1; CTRP2 2.9433 4.6906 2.9118 20.7659
WM793 GDSC1; CTRP2 3.1404 4.0881 3.1394 19.3501
Hs 940.T GDSC1; CTRP2 3.2355 4.4116 3.2299 18.7321
G-mel GDSC1 3.5121 4.7025 3.3113 11.4933
WM115 GDSC1; CTRP2 3.646 5.4263 3.5661 16.2509
MeWo GDSC1; CTRP2 3.7199 5.4618 3.6396 15.7603
MZ-MEL-7 GDSC1 3.7578 4.4729 3.6593 7.7135
RPMI-7951 GDSC1; CTRP2 3.7638 4.3299 3.7637 15.1942
SH-4 GDSC1 3.7967 4.6516 3.6342 7.6862
Mel Ho GDSC1; CTRP2 3.8185 4.5003 3.8068 8.7924
WM1552C GDSC1 3.8245 4.4186 3.7499 6.7166
A-431 GDSC1 3.827 4.6972 3.6476 7.4338
MMAc-SF GDSC1 3.9084 4.4732 3.8219 5.7551
LB2518-MEL GDSC1 3.9101 4.353 3.8636 5.4552
WM278 GDSC1 3.9402 4.802 3.7194 6.3436
SK-MEL-5 GDSC1; CTRP2 3.9886 5.0751 3.9733 13.7473
IST-MEL1 GDSC1 4.0199 5.4136 3.5077 7.6055
IPC-298 GDSC1; CTRP2 4.0209 5.0547 4.0083 13.5228
M14 GDSC1 4.1382 4.9086 3.8643 4.3343
Hs 934.T CTRP2 4.1791 4.9693 4.1751 12.4404
G-361 GDSC1; CTRP2 4.2149 5.1919 4.2006 12.2362
Hs 936.T CTRP2 4.3265 4.9186 4.3256 11.448
COLO 679 GDSC1 4.3469 5.4733 3.7669 4.2881
A-388 GDSC1 4.3797 5.6319 3.7144 4.5862
CHL-1 GDSC1 4.4042 5.8114 3.6446 5.0513
SK-MEL-2 GDSC1; CTRP2 4.4291 5.3557 4.4112 10.8216
LB373-MEL-D GDSC1 4.5146 5.9121 3.6811 4.3974
IGR-37 GDSC1; CTRP2 4.5201 4.9429 4.5199 10.1557
A2058 GDSC1; CTRP2 4.5267 5.1597 4.5238 10.1207
Mel JuSo GDSC1; CTRP2 4.6126 5.2511 4.6084 9.5529
A-375 GDSC1; CTRP2 4.6129 5.3926 4.6005 9.5786
Hs 294T CTRP2 4.6281 5.2601 4.624 9.4492
Hs 688(A).T CTRP2 4.6425 4.9703 4.6424 9.34
SK-MEL-1 GDSC1; CTRP2 4.6728 5.8029 4.6059 9.3677
UACC-257 GDSC1; CTRP2 4.6836 5.8178 4.6145 9.3035
CP66-MEL GDSC1 4.7334 6.1926 3.7034 3.5743
Hs 852.T CTRP2 4.7476 5.4635 4.7357 8.6794
Hs 944.T CTRP2 4.7739 8.0496 3.8544 11.9913
LOX-IMVI GDSC1; CTRP2 4.8572 5.7591 4.814 8.0568
WM1799 CTRP2 4.8718 5.4409 4.8662 7.8306
SK-MEL-30 GDSC1; CTRP2 4.8793 5.7405 4.8411 7.8923
COLO 829 GDSC1; CTRP2 4.8928 6.563 4.6158 8.6783
MDA-MB-435S CTRP2 4.9478 5.8253 4.8996 7.4713
IGR-1 GDSC1; CTRP2 4.954 5.901 4.8903 7.4843
A101D GDSC1; CTRP2 4.9751 5.6712 4.9541 7.1949
Hs 895.T CTRP2 4.9838 9.38 3.4272 13.2224
SK-MEL-3 GDSC1; CTRP2 5.0083 6.0159 4.9213 7.2064
WM983B CTRP2 5.0144 5.9643 4.9411 7.1167
IGR-39 CTRP2 5.063 6.1674 4.9374 6.9824
451Lu GDSC1 5.0685 7.318 3.3911 5.0342
COLO 800 GDSC1; CTRP2 5.1 7.1995 4.5683 8.306
SK-MEL-28 GDSC1; CTRP2 5.1038 5.8756 5.0586 6.4217
HT-144 GDSC1; CTRP2 5.2257 5.9124 5.1831 5.601
WM266-4 CTRP2 5.2428 8.3725 4.1596 9.6182
K029AX CTRP2 5.3024 5.9335 5.262 5.0826
CJM [Human melanoma] CTRP2 5.3285 5.8956 5.2981 4.8737
RVH-421 GDSC1; CTRP2 5.3298 8.6464 4.1086 9.6291
VMRC-MELG GDSC1 5.3306 7.2822 3.574 3.0922
UACC-62 GDSC1; CTRP2 5.3466 5.9156 5.3137 4.7619
WM88 CTRP2 5.4383 6.1534 5.3503 4.3506
SK-MEL-31 CTRP2 5.5118 6.1421 5.4338 3.8257
WT2-iPS GDSC1; CTRP2 5.5382 6.2022 5.442 3.7181
DJM-1 GDSC1 5.5743 7.4175 3.6511 2.1254
GAK GDSC1 5.6306 7.882 3.478 3.1487
COLO 783 GDSC1 5.9368 7.2306 3.8951 0.4593
CP50-MEL-B GDSC1 6.0619 7.7381 3.7551 0.9279
Hs 938.T GDSC1 6.1193 7.8095 3.7524 0.8872
SK-MEL-24 GDSC1 6.5193 8.0546 3.8227 0.3684
Hs 839.T CTRP2 8.5472 21.9436 0.072 18.4325
HMCB CTRP2 13.5841 29.5519 -0.1783 12.5579
EquiPSC Line K2 GDSC1 5.501 8.4659 3.1308 5.8647
⏷ Show the Full List of 75 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYAE-1 GDSC1 3.5736 4.2753 3.5175 9.7198
KYSE-50 GDSC1 3.7537 4.5698 3.62 8.0131
OACM5.1 C GDSC1 3.827 9.6285 1.2457 24.2452
ESO-26 GDSC1 3.8777 4.4667 3.791 6.1383
SK-GT-4 GDSC1 3.9218 4.7952 3.7037 6.549
ESO-51 GDSC1 4.0031 5.0197 3.6815 6.3375
OACP4 C GDSC1 4.0332 5.2409 3.6041 6.8018
TE-12 GDSC1 4.2363 6.2023 3.3095 8.2986
KYSE-220 GDSC1 4.3608 5.5695 3.7302 4.5274
FLO-1 GDSC1 5.1432 7.7731 3.2236 6.0914
HCE-4 GDSC1 5.8618 8.1582 3.4841 2.694
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 4.5579 5.9844 4.4381 10.3204
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-7 GDSC1 3.0115 5.8507 2.3066 21.2887
CHP-134 GDSC1 3.0927 4.1903 3.0139 15.8772
SJNB-17 GDSC1 3.1485 8.4716 1.2031 27.4471
GI-ME-N GDSC1 3.4805 7.9148 1.7837 22.5729
KP-N-YS GDSC1 3.6047 4.6508 3.4299 10.1575
NH-6 CTRP2 3.7533 6.9127 3.2628 17.0348
IMR-5 GDSC1 3.7752 4.4281 3.6932 7.3817
LA-N-6 GDSC1 3.805 4.5523 3.6816 7.3024
SJNB-6 GDSC1 3.8155 4.5267 3.7023 7.0994
NB69 GDSC1 3.8395 4.6723 3.671 7.1994
NH-12 GDSC1 3.8459 4.7772 3.6335 7.4422
SK-N-MC-IXC GDSC1 3.8501 4.2333 3.8283 6.0384
TGW GDSC1 3.8917 4.4708 3.8047 5.9661
SiMa GDSC1 3.9497 6.8889 2.7164 14.0221
Kelly GDSC1; CTRP2 3.9574 4.5204 3.9572 13.9046
CHP-212 GDSC1 3.9817 4.6471 3.83 5.3189
MHH-NB-11 GDSC1; CTRP2 3.9852 4.7701 3.983 13.726
NB1 GDSC1; CTRP2 4.059 4.8514 4.056 13.237
CHP-126 GDSC1; CTRP2 4.0748 5.9455 3.9211 13.6571
SJNB-14 GDSC1 4.0913 4.8005 3.871 4.4899
SJNB-10 GDSC1 4.1119 5.6541 3.4736 7.4914
SJNB-13 GDSC1 4.127 5.4511 3.5877 6.5379
SK-N-SH GDSC1; CTRP2 4.17 5.5122 4.1157 12.6722
SK-N-FI GDSC1; CTRP2 4.1724 5.6263 4.0985 12.7244
SJNB-12 GDSC1 4.1834 5.4058 3.6606 5.7399
GOTO GDSC1 4.2025 5.6546 3.5536 6.5061
SJNB-5 GDSC1 4.2151 5.4546 3.6643 5.5872
SK-N-AS GDSC1 4.4025 5.7104 3.6937 4.6706
SK-N-BE(2)-M17 GDSC1 4.4914 7.155 3.044 9.4633
KP-N-SI9s CTRP2 4.5819 5.6083 4.5428 9.8762
SK-N-BE(2) CTRP2 4.8792 5.8943 4.8104 8.0002
SK-N-DZ GDSC1 5.0137 7.4167 3.3062 5.8199
KP-N-YN GDSC1; CTRP2 5.2225 9.3269 3.6763 11.6563
NB(TU)1 GDSC1 5.3749 7.7165 3.4013 4.2131
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 3.476 4.5446 3.4711 17.1271
HuCC-T1 GDSC1; CTRP2 4.0105 5.1164 3.9931 13.6086
SNU-478 CTRP2 4.204 5.1895 4.1894 12.3098
HuH-28 CTRP2 4.4282 5.1201 4.4245 10.7797
SNU-308 CTRP2 4.524 5.7946 4.4461 10.3971
SNU-869 CTRP2 4.6363 6.0435 4.508 9.8297
SNU-1196 CTRP2 4.7643 6.3096 4.5669 9.2315
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 85 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 578Bst CTRP2 0.669 3.0581 -2.7452 1.339
OCUB-M GDSC1 2.805 5.6073 2.1986 23.0994
HCC1954 GDSC1; CTRP2 3.538 5.4464 3.446 17.0125
MDA-MB-453 GDSC1; CTRP2 3.5926 5.2013 3.5429 16.5023
HCC2218 GDSC1; CTRP2 3.7381 6.9029 3.25 17.1264
HCC1599 GDSC1 3.7534 4.3272 3.7 7.4571
Evsa-T GDSC1 3.8001 4.3354 3.7487 6.8614
HCC1569 GDSC1 3.8844 5.3251 3.4213 8.8641
YMB-1-E GDSC1 3.9052 4.9245 3.6288 7.1899
BT-474 GDSC1; CTRP2 3.9084 5.2928 3.8673 14.3691
AU565 GDSC1; CTRP2 3.9145 4.9537 3.6248 4.3207
MDA-MB-175-VII GDSC1 3.9243 4.8556 3.6793 6.7202
HCC70 GDSC1 3.9495 4.6528 3.7941 5.7435
ZR-75-30 GDSC1; CTRP2 3.9564 7.1817 3.3787 16.0213
HCC1143 CTRP2 3.9673 7.2665 3.357 16.0742
UACC-893 GDSC1 3.9959 5.1911 3.5927 7.052
HMC-1-8 CTRP2 4.0391 4.8496 3.9937 7.3423
COLO 824 GDSC1 4.0698 5.2824 3.6182 6.5357
T-47D GDSC1; CTRP2 4.0746 5.3419 4.0379 13.2471
MDA-MB-468 GDSC1; CTRP2 4.0851 5.92 3.9387 13.562
DU4475 GDSC1; CTRP2 4.1076 4.9749 4.1018 12.9229
KPL-1 CTRP2 4.1229 4.9623 4.118 12.8176
UACC-812 GDSC1 4.1458 5.0874 3.784 4.9268
EFM-19 GDSC1 4.1488 5.6033 3.5318 6.888
HCC1500 GDSC1; CTRP2 4.1549 6.2141 3.9336 13.3686
CAMA-1 GDSC1; CTRP2 4.2261 5.9622 4.0819 12.616
HCC1395 GDSC1; CTRP2 4.2262 5.344 4.1985 12.2067
ZR-75-1 CTRP2 4.2398 5.0384 4.2347 12.0394
HCC1419 GDSC1; CTRP2 4.3961 6.723 4.0235 12.3309
CAL-85-1 GDSC1; CTRP2 4.5234 6.8664 4.1051 11.6622
HCC1806 GDSC1; CTRP2 4.5794 5.4918 4.5557 9.8402
HCC202 CTRP2 4.6059 9.7841 2.8729 16.345
CAL-51 GDSC1; CTRP2 4.6277 5.8824 4.5393 9.7441
MCF-7 GDSC1; CTRP2 4.6867 5.8695 4.6066 9.3219
MDA-MB-231 GDSC1; CTRP2 4.7001 6.0825 4.5668 9.4233
HCC1187 GDSC1 4.7089 7.6565 2.9651 9.3462
MDA-MB-361 GDSC1; CTRP2 4.7815 5.9907 4.6805 8.7655
CAL-148 GDSC1; CTRP2 4.8644 6.2177 4.7054 8.4251
HCC1428 GDSC1; CTRP2 4.9373 7.4637 4.2849 9.8528
EFM-192A GDSC1; CTRP2 4.9664 6.062 4.8631 7.5434
MFM-223 GDSC1 4.9823 7.387 3.2988 5.9631
MDA-MB-330 GDSC1 5.0168 7.3095 3.3601 5.4044
BT-483 GDSC1 5.1104 7.7029 3.2349 6.0945
JIMT-1 GDSC1; CTRP2 5.1153 6.1 5.0148 6.5433
HCC1937 GDSC1; CTRP2 5.1169 6.4303 4.9056 6.9448
HCC38 GDSC1; CTRP2 5.2466 6.3291 5.0822 5.9081
HDQ-P1 GDSC1; CTRP2 5.2881 6.3442 5.1214 5.6417
CAL-120 GDSC1; CTRP2 5.3395 6.0473 5.2743 4.9243
BT-549 GDSC1; CTRP2 5.3611 6.3033 5.2148 5.0808
MDA-MB-157 GDSC1; CTRP2 5.4002 6.8927 5.0105 5.7735
BT-20 GDSC1; CTRP2 5.511 6.1218 5.4394 3.8072
MDA-MB-436 GDSC1 6.133 8.9174 3.3002 3.3945
MRK-nu-1 GDSC1 6.3167 7.8236 3.8281 0.4554
HCC2157 GDSC1 6.3337 8.0784 3.7406 0.758
MDA-MB-415 GDSC1 6.6788 8.324 3.787 0.3935
Hs 578T GDSC1 6.8675 8.7817 3.6949 0.5708
BT 416 CTRP2 -0.9005 188.5413 -91.0542 49.8377
BT 286 CTRP2 3.2143 4.6776 3.1955 18.9175
BT 172 CTRP2 3.8871 5.5305 3.8078 14.6433
BT 216 CTRP2 3.9246 5.4137 3.8677 14.3158
BT 248 CTRP2 4.1673 5.6419 4.0901 12.7701
BT 131 CTRP2 4.229 5.2268 4.2126 12.1496
BT 232 CTRP2 4.2644 5.6159 4.1998 12.0796
BT 139 CTRP2 4.2872 5.5219 4.24 11.867
BT147 CTRP2 4.3098 5.944 4.1778 12.0152
BT 228 CTRP2 4.3577 5.3415 4.3375 11.3052
BT 440 CTRP2 4.3698 5.8429 4.2677 11.5095
BT 504 CTRP2 4.3809 5.0481 4.3784 11.0908
BT 245 CTRP2 4.4063 5.659 4.3452 11.1221
BT 340 CTRP2 4.5183 5.5219 4.4871 10.2726
BT 330 CTRP2 4.536 5.0725 4.535 10.0526
BT 159 CTRP2 4.5558 5.5671 4.5209 10.0359
BT 359 CTRP2 4.6146 6.0736 4.476 10.0113
BT 444 CTRP2 4.7381 5.5317 4.7192 8.7663
BT 112 CTRP2 4.79 6.8828 4.3813 9.8635
BT 333 CTRP2 4.828 6.08 4.707 8.5284
BT 482 CTRP2 4.8325 5.5109 4.8205 8.1142
BT 145 CTRP2 4.8472 8.3376 3.7935 12.0558
BT 498 CTRP2 4.9682 5.886 4.9091 7.3734
BT 422 CTRP2 5.0913 5.868 5.0466 6.5032
BT164 CTRP2 5.1243 6.2166 4.9884 6.6134
BT 328 CTRP2 5.2955 5.9521 5.2503 5.1453
BT 224 CTRP2 5.3371 9.0668 3.9097 10.4361
BT 179 CTRP2 5.4023 5.8642 5.3833 4.3425
BT 320 CTRP2 5.4079 6.5045 5.1863 5.0598
⏷ Show the Full List of 85 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 4.1804 5.5065 4.1278 12.5974
Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-247MG GDSC1 -0.4272 7.908 -2.143 54.5141
SF539 GDSC1; CTRP2 3.3192 4.0719 3.319 18.1564
TM-31 CTRP2 3.3859 6.2586 3.0818 18.7823
KINGS-1 GDSC1 3.738 4.6798 3.5608 8.5205
SK-MG-1 GDSC1 3.7752 4.4353 3.6908 7.3984
GI-1 GDSC1 3.7936 4.6064 3.6487 7.5977
D-566MG GDSC1 3.7939 4.3996 3.7227 7.0742
D-423MG GDSC1 3.8137 4.6518 3.6521 7.4689
YKG-1 GDSC1 3.8218 4.6773 3.6503 7.4408
KS-1 [Human Krukenberg tumour] GDSC1 3.8224 5.8255 3.1219 11.44
H4 GDSC1 3.85 4.5219 3.7412 6.6389
MOG-G-CCM GDSC1 3.8615 4.8887 3.6007 7.6101
AM-38 GDSC1 3.8721 4.6676 3.7071 6.7701
SNU-466 CTRP2 3.9418 4.6169 3.9412 14.0097
MOG-G-UVW GDSC1 3.9559 4.8652 3.7067 6.3639
KNS-81-FD GDSC1 3.9767 5.381 3.4829 7.983
CAS-1 GDSC1; CTRP2 4.0258 4.9288 4.0198 13.4682
KNS-60 CTRP2 4.0402 4.8763 3.9894 7.3548
SF268 GDSC1; CTRP2 4.0669 5.2615 4.039 13.2683
LN-405 GDSC1 4.0947 4.7591 3.8938 4.3003
SW1088 GDSC1; CTRP2 4.0964 5.4526 4.0459 13.1493
U-87MG ATCC GDSC1; CTRP2 4.1038 5.0821 4.0926 12.9662
LN-229 GDSC1; CTRP2 4.1512 4.8235 4.15 12.6167
Hs 683 GDSC1; CTRP2 4.1711 4.8317 4.1699 12.4841
SNU-1105 CTRP2 4.1826 5.0395 4.176 12.4256
42-MG-BA GDSC1; CTRP2 4.2259 12.1712 1.3592 22.89
M059J GDSC1 4.3373 5.5308 3.7302 4.611
GaMG GDSC1; CTRP2 4.3478 5.4632 4.3131 11.4207
KNS-42 GDSC1 4.3648 5.144 3.946 2.8129
T98G GDSC1; CTRP2 4.3723 6.8254 3.9595 12.6413
SNU-201 CTRP2 4.3836 4.9627 4.3827 11.0675
LN-18 GDSC1; CTRP2 4.4058 4.9688 4.405 10.9191
Daoy GDSC1; CTRP2 4.4535 6.0785 4.2987 11.1413
D-336MG GDSC1 4.504 7.1222 3.0705 9.2146
ONS-76 GDSC1; CTRP2 4.5176 5.768 4.4447 10.4221
KG-1-C CTRP2 4.526 5.0754 4.5249 10.1196
U-251MG GDSC1; CTRP2 4.5378 6.0922 4.3869 10.5667
GB-1 GDSC1; CTRP2 4.6346 5.788 4.5675 9.6232
KNS-81 CTRP2 4.6787 5.2074 4.677 9.1041
SNU-626 CTRP2 4.6837 5.6151 4.6507 9.1772
D-542MG GDSC1 4.7055 6.5876 3.4907 5.2898
KALS-1 GDSC1; CTRP2 4.7277 6.1097 4.5891 9.2593
PFSK-1 GDSC1 4.7888 6.9829 3.3576 6.0697
SNB-75 GDSC1; CTRP2 4.7979 6.3367 4.5943 9.0318
U-118MG GDSC1; CTRP2 4.8038 6.8136 4.4237 9.6617
SF126 GDSC1; CTRP2 4.8286 6.6547 4.5123 9.2534
Onda 10 GDSC1 4.9944 7.2519 3.3725 5.3718
8-MG-BA GDSC1; CTRP2 5.0047 11.5932 2.3621 17.4205
GMS-10 CTRP2 5.018 5.6895 4.9974 6.9076
NMC-G1 GDSC1; CTRP2 5.02 6.3373 4.8347 7.4896
M059K CTRP2 5.0247 23.6647 -3.6293 32.7373
Onda 11 GDSC1 5.0616 8.6383 2.7449 9.9067
DK-MG GDSC1; CTRP2 5.0791 13.3335 1.5671 20.1811
GOS-3 CTRP2 5.2057 6.1769 5.0898 5.9988
SF295 GDSC1; CTRP2 5.21 6.4481 4.9987 6.3282
DBTRG-05MG GDSC1; CTRP2 5.2745 6.2942 5.1248 5.6679
YH-13 GDSC1; CTRP2 5.3094 13.194 1.84 18.7007
A-172 GDSC1; CTRP2 5.3895 6.3169 5.2404 4.9033
SW1783 GDSC1; CTRP2 5.4358 6.7627 5.1048 5.3066
Becker GDSC1; CTRP2 5.4488 6.205 5.3444 4.3417
D-502MG GDSC1 5.4567 7.3849 3.6008 2.6596
SNU-738 CTRP2 5.6012 6.7322 5.2858 4.1619
D283 Med GDSC1 5.8166 7.3636 3.793 0.9948
LNZTA3WT4 GDSC1 6.0585 8.9402 3.249 3.8577
D-392MG GDSC1 6.3683 13.2975 1.4039 14.9766
D-263MG GDSC1 6.6431 7.9664 3.8982 0.1578
CCF-STTG1 CTRP2 7.7804 16.4771 2.1946 12.7431
⏷ Show the Full List of 67 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 3.9365 4.8967 3.6729 6.7096
TGBC1TKB GDSC1 4.2685 5.252 3.8116 4.2226
TGBC24TKB GDSC1 4.3197 6.001 3.4805 6.6438
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-7 CTRP2 3.5353 6.1424 3.2788 17.6163
HEC-1-A CTRP2 3.6837 5.4321 3.6058 15.9932
ESS-1 GDSC1; CTRP2 3.8856 5.9653 3.7095 14.9961
JHUEM-2 CTRP2 3.9776 5.0511 3.8784 7.9865
RL95-2 GDSC1; CTRP2 4.0074 4.8131 4.0046 13.58
JHUEM-1 CTRP2 4.105 5.4014 4.0625 13.0646
HEC-50B CTRP2 4.1687 7.6036 3.4315 15.2365
HEC-6 CTRP2 4.1873 5.1349 4.0828 6.5131
MFE-296 GDSC1; CTRP2 4.1882 5.6104 4.1186 12.6043
EN GDSC1; CTRP2 4.3943 5.5293 4.3536 11.1313
HEC-108 CTRP2 4.4452 4.9941 4.4444 10.6569
HEC-1-B CTRP2 4.47 6.0362 4.3285 10.9835
HEC-151 CTRP2 4.473 5.4133 4.4518 10.5405
KLE GDSC1; CTRP2 4.5713 5.8111 4.4939 10.0806
EFE-184 CTRP2 4.6613 5.4938 4.6422 9.2788
HEC-251 CTRP2 4.7018 6.064 4.227 4.4567
HEC-59 CTRP2 4.9928 6.4345 4.3059 3.434
MFE-280 GDSC1 5.1347 8.7847 2.7263 9.8254
HEC-265 CTRP2 5.1591 6.8882 4.2163 3.4988
AN3-CA GDSC1; CTRP2 5.2157 6.3479 5.0421 6.1475
MFE-319 GDSC1; CTRP2 5.4139 6.3694 5.2466 4.811
JHUEM-3 CTRP2 5.4915 6.2984 5.3567 4.1736
Ishikawa (Heraklio) 02 ER- CTRP2 5.3329 6.9368 4.3266 2.6826
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-1M GDSC1 2.514 3.8051 2.4622 22.9299
KTCTL-140 GDSC1 2.9615 4.0643 2.8988 17.4094
769-P GDSC1; CTRP2 3.0067 5.1869 2.9178 20.5402
KTCTL-21 GDSC1 3.2699 5.5381 2.709 17.1113
KTCTL-26A GDSC1 3.349 4.3542 3.2512 12.8058
RXF 393L GDSC1 3.4677 5.0062 3.1428 12.9422
KTCTL-195 GDSC1 3.7804 4.5387 3.6603 7.5845
LB1047-RCC GDSC1 3.8318 5.2195 3.4197 9.1154
KTCTL-13 GDSC1 3.8851 4.7506 3.6855 6.8641
KMRC-3 CTRP2 3.8954 5.149 3.8696 14.4035
BB65-RCC GDSC1 3.913 4.6632 3.7517 6.2375
NCC021 GDSC1 3.9707 4.7963 3.7529 5.9459
A-704 GDSC1 3.9738 4.74 3.7813 5.7189
UO-31 GDSC1; CTRP2 4.0121 5.311 3.9753 13.6637
TK-10 GDSC1 4.0126 5.2611 3.5749 7.1164
HA7-RCC GDSC1 4.0963 5.1957 3.6852 5.903
TUHR4TKB CTRP2 4.1786 5.0406 4.1719 12.4524
VMRC-RCW GDSC1; CTRP2 4.2128 5.4149 4.1757 12.3281
TUHR10TKB CTRP2 4.2513 5.0236 4.247 11.9601
A-498 GDSC1 4.3256 5.4009 3.7855 4.2175
KMRC-20 GDSC1; CTRP2 4.3403 5.242 4.3275 11.3959
SW156 GDSC1 4.3409 5.8717 3.5628 5.9183
786-O GDSC1; CTRP2 4.3751 7.6409 3.6303 13.9085
KMRC-2 CTRP2 4.4386 5.6797 4.3764 10.911
BFTC-909 GDSC1; CTRP2 4.5984 5.5045 4.5744 9.7147
VMRC-RCZ GDSC1; CTRP2 4.7473 6.3839 4.5235 9.4426
RCC10RGB GDSC1; CTRP2 4.8169 5.5349 4.8019 8.2283
SNU-1272 CTRP2 5.2162 6.11 5.1218 5.8501
KMRC-1 GDSC1; CTRP2 5.2886 13.6892 1.5752 19.6924
TUHR14TKB CTRP2 5.3145 9.0734 3.8856 10.5857
OS-RC-2 GDSC1; CTRP2 5.4002 7.4922 4.7324 6.8984
Caki-2 CTRP2 5.4105 5.9052 5.3851 4.3101
SN12C GDSC1 5.4182 8.191 3.2069 5.514
LB2241-RCC GDSC1 5.9442 7.856 3.6539 1.567
SW13 GDSC1 5.9745 7.9547 3.628 1.67
CAL-54 GDSC1 6.4128 10.8551 2.5898 7.5162
LB996-RCC GDSC1 6.5354 8.4348 3.6899 0.8042
ACHN GDSC1; CTRP2 10.451 19.5863 2.4982 7.9823
Caki-1 GDSC1; CTRP2 10.5088 18.5538 3.002 6.195
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-175 GDSC1 1.6087 6.1348 0.725 38.1212
T84 GDSC1; CTRP2 3.6566 5.046 3.6282 16.0036
SNU-407 GDSC1; CTRP2 3.6678 5.1188 3.6326 15.952
HT115 GDSC1; CTRP2 3.7072 4.5066 3.706 15.5745
SW626 GDSC1 3.7317 4.6877 3.5509 8.6244
GP5d GDSC1 3.7386 5.0259 3.4145 9.5938
LS513 GDSC1; CTRP2 3.8314 4.8916 3.8217 14.776
CCK-81 GDSC1 3.8681 4.832 3.6325 7.3409
OUMS-23 CTRP2 3.8829 4.8674 3.8758 14.4238
SNU-1040 GDSC1 3.9375 4.5168 3.8368 5.4941
NCI-H747 GDSC1; CTRP2 4.1646 6.3733 3.8946 13.4831
RKO GDSC1; CTRP2 4.2082 5.8378 4.0929 12.6319
HCT 15 GDSC1; CTRP2 4.2089 5.047 4.2027 12.2491
SW1463 GDSC1 4.2774 5.6346 3.6282 5.6349
SK-CO-1 CTRP2 4.358 5.506 4.3182 11.3702
SNU-C2A CTRP2 4.4011 10.3553 1.8355 15.6996
LS1034 GDSC1; CTRP2 4.4108 5.4864 4.3772 10.997
SNU-61 GDSC1; CTRP2 4.4128 5.6964 4.3453 11.101
NCI-H508 CTRP2 4.4314 5.3457 4.4145 10.803
COLO201 CTRP2 4.4383 5.6991 4.3724 10.9261
HCC2998 GDSC1 4.4481 5.7774 3.6965 4.4944
CW-2 GDSC1; CTRP2 4.4628 6.211 4.2701 11.2173
COLO 320HSR GDSC1 4.4925 7.8491 2.6983 12.1097
SW48 GDSC1; CTRP2 4.5233 6.003 4.3955 10.5794
SNU-C2B GDSC1 4.5331 6.2947 3.5055 5.7128
LoVo GDSC1; CTRP2 4.5353 5.6952 4.478 10.2496
SNU-C5 GDSC1; CTRP2 4.5503 5.7722 4.4792 10.1982
SNU-1033 CTRP2 4.5504 5.8445 4.4638 10.2522
COLO 320 CTRP2 4.5937 6.8163 4.1994 11.1053
NCI-H716 GDSC1; CTRP2 4.6458 5.9009 4.5547 9.6332
CaR-1 GDSC1 4.6624 7.183 3.1643 7.9589
C2BBe1 GDSC1; CTRP2 4.6673 6.5137 4.3915 10.1681
CL-11 GDSC1; CTRP2 4.725 5.8839 4.645 9.0666
SNU-C1 GDSC1; CTRP2 4.7379 6.0941 4.6047 9.1715
LS180 GDSC1; CTRP2 4.7443 5.6609 4.4606 3.3234
LS411N GDSC1; CTRP2 4.757 5.7556 4.7064 8.7498
GP2d CTRP2 4.8009 6.6659 4.4784 9.4598
HT-55 GDSC1; CTRP2 4.8066 5.891 4.7321 8.5039
HT-29 GDSC1; CTRP2 4.8743 6.6121 4.1146 4.5528
HCT 8 CTRP2 4.8797 5.548 4.8667 7.8031
SNU-81 GDSC1 4.9078 6.7976 3.5318 4.4018
KM12 GDSC1; CTRP2 4.9395 6.0151 4.8465 7.6853
SNU-C4 CTRP2 4.9616 5.593 4.9486 7.2577
COLO205 GDSC1; CTRP2 4.9812 5.8474 4.9313 7.2544
DLD-1 CTRP2 5.0635 6.1736 4.936 6.9862
RCM-1 [Human ESC] GDSC1; CTRP2 5.0764 6.0713 4.9805 6.7852
SW1417 GDSC1; CTRP2 5.1333 6.4149 4.929 6.8096
MDST8 GDSC1; CTRP2 5.1588 6.2402 5.0182 6.4015
COLO 678 GDSC1; CTRP2 5.1818 6.5831 4.916 6.7238
SW620 GDSC1; CTRP2 5.2094 7.104 4.7222 7.4121
SW948 GDSC1; CTRP2 5.2154 6.2336 5.0817 6.0002
HCC-56 CTRP2 5.2317 5.9488 5.1816 5.5875
HCT 116 GDSC1; CTRP2 5.2684 8.8929 3.3035 7.3869
LS123 GDSC1; CTRP2 5.5837 7.0907 5.1009 4.9549
SNU-503 CTRP2 5.5974 6.1333 5.5297 3.2193
SW837 GDSC1 5.7919 7.8372 3.5854 2.1803
SW1116 GDSC1 6.5101 7.735 3.93 0.1362
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 3.7645 4.4525 3.6735 7.5777
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-182 CTRP2 2.6435 7.0928 2.0017 24.9204
HuH-6 CTRP2 2.7308 4.8091 2.6755 22.2628
JHH-7 GDSC1 3.0498 4.2492 2.9528 16.535
JHH-1 GDSC1; CTRP2 3.6693 5.2312 3.6207 15.988
Li-7 CTRP2 3.7309 5.1837 3.6921 15.5438
SNU-761 CTRP2 3.7437 5.7051 3.4024 10.6177
Hep-G2 CTRP2 3.8845 5.371 3.8311 14.5708
SNU-878 CTRP2 4.0392 5.1776 4.018 13.43
Hep 3B2.1-7 GDSC1; CTRP2 4.1121 5.3214 4.0802 12.9808
HLF CTRP2 4.1837 5.6791 4.1006 12.6817
JHH-2 GDSC1; CTRP2 4.2148 5.6461 4.1406 12.4433
HuH-1 GDSC1; CTRP2 4.6063 5.8234 4.5293 9.8465
Huh-7 GDSC1 4.6432 5.9696 3.748 3.4869
SNU-398 GDSC1; CTRP2 4.7117 5.7458 4.6593 9.0582
SNU-423 GDSC1; CTRP2 5.1166 6.3876 4.9211 6.8871
PLC/PRF/5 CTRP2 5.1297 7.4324 4.4932 8.5314
JHH-5 CTRP2 5.1364 8.3864 4.0513 10.3114
SNU-475 GDSC1; CTRP2 5.2652 5.9175 5.2251 5.3291
SNU-449 GDSC1; CTRP2 5.2682 6.3632 5.093 5.8056
SNU-387 GDSC1; CTRP2 5.2824 6.7805 4.9392 6.3621
JHH-4 GDSC1; CTRP2 5.3538 8.6248 4.1415 9.4386
SK-HEP-1 GDSC1; CTRP2 5.3977 11.596 2.7128 15.1889
Hep-G2/C3A GDSC1 5.4687 6.742 3.8815 0.9377
HLE GDSC1 5.6018 7.8722 3.4659 3.2851
JHH-6 GDSC1; CTRP2 5.6809 6.0059 5.6575 2.5027
SNU-886 CTRP2 5.8442 6.8283 5.4753 2.8087
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 210 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1703 GDSC1; CTRP2 0.7952 12.1479 -2.0192 40.7604
SBC-3 GDSC1 2.2149 3.3474 2.1979 26.4444
DMS 273 GDSC1; CTRP2 2.7761 5.8268 2.5346 22.6111
IST-SL1 GDSC1 2.8122 4.3018 2.6797 19.7395
NCI-H1341 CTRP2 2.885 4.4306 2.8695 21.1003
LC-2/ad GDSC1 2.8875 3.8698 2.8527 18.1519
NCI-H446 GDSC1; CTRP2 2.9253 4.0185 2.9234 20.786
Lu-139 GDSC1 2.9955 4.7633 2.7337 18.3471
NCI-H810 GDSC1; CTRP2 3.0624 4.1339 3.0603 19.8733
LXF 289 GDSC1; CTRP2 3.2405 4.9558 3.1986 18.8212
NCI-H647 GDSC1; CTRP2 3.2618 5.4032 3.1556 18.9014
NCI-H2196 GDSC1; CTRP2 3.2694 5.7011 3.1023 19.0649
UMC-11 GDSC1 3.286 5.0032 2.953 15.2493
NCI-H211 GDSC1; CTRP2 3.3371 6.7176 2.882 19.6605
IST-SL2 GDSC1 3.3489 6.4833 2.3522 19.3301
Ms-1 GDSC1 3.36 4.6524 3.1664 13.333
NCI-H1436 GDSC1 3.4506 4.8912 3.172 12.8162
NCI-H2087 GDSC1; CTRP2 3.5031 4.7518 3.4903 16.9734
NCI-H1437 GDSC1 3.5489 4.7981 3.3133 11.2864
LK-2 GDSC1 3.5548 8.9618 1.3353 24.9021
EBC-1 GDSC1; CTRP2 3.5817 5.2446 3.5254 16.5976
NCI-H841 GDSC1; CTRP2 3.5974 6.4328 3.2586 17.5042
NCI-H2804 GDSC1 3.6157 4.8672 3.3556 10.6376
HCC1588 CTRP2 3.6378 4.8858 3.5495 10.3671
NCI-H1694 GDSC1; CTRP2 3.6611 4.6808 3.6557 15.896
HCC4006 CTRP2 3.7077 6.7395 3.2756 17.1179
ABC-1 GDSC1 3.7179 5.4966 3.1779 11.4769
HCC33 GDSC1 3.7237 4.2132 3.6953 7.6611
NCI-H1688 GDSC1 3.7679 10.4777 0.771 26.8827
NCI-H2731 GDSC1 3.7685 7.9734 2.0168 19.8051
COR-L23 GDSC1 3.7986 4.3251 3.75 6.8607
NCI-H847 GDSC1 3.8048 4.3682 3.7443 6.864
NCI-H2795 GDSC1 3.8113 4.5716 3.681 7.274
NCI-H1048 GDSC1 3.8218 4.4956 3.7205 6.9373
LCLC-97TM1 GDSC1; CTRP2 3.8252 5.7105 3.7048 15.1997
NCI-H290 GDSC1 3.8352 4.4252 3.7593 6.5917
NCI-H2722 GDSC1 3.8532 4.358 3.8001 6.2099
COR-L311 GDSC1 3.8832 5.5394 3.3177 9.6657
NCI-H1581 GDSC1; CTRP2 3.8842 5.8602 3.7346 14.9106
EMC-BAC-1 GDSC1 3.8995 5.261 3.4665 8.45
NCI-H64 GDSC1 3.9196 4.2838 3.8927 5.2038
MOR/CPR CTRP2 3.9223 4.6262 3.9036 8.077
NCI-H2106 CTRP2 3.9267 5.5223 3.852 14.3634
NCI-H1648 GDSC1 3.9697 5.3719 3.4807 8.0302
Calu-3 GDSC1; CTRP2 3.9701 5.5597 3.8922 14.0855
NCI-H889 CTRP2 3.9979 5.8889 3.8515 14.1424
NCI-H596 GDSC1 4.008 4.7239 3.8233 5.24
NCI-H1563 GDSC1; CTRP2 4.0294 5.2296 4.0027 13.5143
DMS 454 CTRP2 4.0311 6.1561 3.8158 14.1699
SK-MES-1 GDSC1; CTRP2 4.0479 5.5044 3.9857 13.5127
SK-LU-1 GDSC1; CTRP2 4.0531 5.1564 4.0344 13.3294
PaCa-3 GDSC1 4.0764 5.1947 3.6672 6.1279
COR-L321 GDSC1 4.0807 4.9342 3.7971 5.1041
NCI-H1734 GDSC1; CTRP2 4.0848 5.0693 4.0737 13.0924
NCI-H1155 GDSC1; CTRP2 4.0864 5.0755 4.0749 13.0829
COR-L95 GDSC1; CTRP2 4.0891 6.0844 3.8995 13.6911
NCI-H2227 GDSC1 4.0907 4.9362 3.8058 4.9928
HCC44 GDSC1; CTRP2 4.104 5.5945 4.0304 13.179
SHP-77 GDSC1; CTRP2 4.1316 5.3769 4.0941 12.8702
COR-L303 GDSC1 4.1322 4.7705 3.925 3.8931
NCI-H2081 GDSC1; CTRP2 4.1468 5.781 4.039 13.0143
COLO 699 CTRP2 4.1514 5.8945 3.7547 7.9648
NCI-H2591 GDSC1 4.2067 5.3934 3.6874 5.4374
DMS 53 GDSC1; CTRP2 4.2377 7.0908 3.7134 13.9577
NCI-H2171 GDSC1; CTRP2 4.2475 5.5024 4.2004 12.1313
NCI-H2135 GDSC1 4.2506 5.4056 3.7196 5.0154
NCI-H661 GDSC1; CTRP2 4.2509 7.1838 3.6904 14.0094
NCI-H1573 GDSC1; CTRP2 4.2652 5.5186 4.2169 12.0176
NCI-H1975 GDSC1 4.273 5.4718 3.7057 5.0399
NCI-H1184 CTRP2 4.2754 5.7742 4.1804 12.1126
RERF-LC-Sq1 GDSC1 4.2842 5.6821 3.6102 5.7517
NCI-H1838 GDSC1; CTRP2 4.2874 5.2193 4.2741 11.75
NCI-H187 GDSC1 4.2932 5.0167 3.9503 3.0367
HCC95 CTRP2 4.3057 5.4496 4.27 11.7043
NCI-H2126 CTRP2 4.323 5.9464 4.1916 11.9254
NCI-H3122 GDSC1 4.3252 5.6647 3.6533 5.2612
SW1271 GDSC1; CTRP2 4.327 6.1865 4.1295 12.1377
NCI-H1304 GDSC1 4.3329 5.4671 3.7585 4.4039
DV-90 CTRP2 4.3464 5.9516 4.2159 11.7663
NCI-H520 GDSC1; CTRP2 4.3679 5.6871 4.2985 11.407
NCI-H2405 GDSC1; CTRP2 4.3709 5.7628 4.2866 11.4393
EMC-BAC-2 GDSC1 4.383 5.9042 3.5811 5.6248
NCI-H2122 GDSC1; CTRP2 4.4046 5.4807 4.3713 11.0373
NCI-H524 GDSC1 4.4084 6.0901 3.5088 6.1063
HCC827 GDSC1; CTRP2 4.4113 6.3521 3.8094 7.0259
HOP-62 GDSC1; CTRP2 4.4478 5.332 4.4328 10.6873
Lu-135 GDSC1 4.4498 6.6035 3.2859 7.7166
Lu-165 GDSC1 4.4504 5.4711 3.8506 3.2773
NCI-H2023 GDSC1; CTRP2 4.4509 5.4178 4.428 10.6932
NCI-H1666 GDSC1; CTRP2 4.4518 5.7439 4.3782 10.8632
NCI-H2228 GDSC1; CTRP2 4.462 5.4508 4.436 10.6298
NCI-H2141 GDSC1 4.4689 5.8725 3.6654 4.6691
NCI-H69 GDSC1; CTRP2 4.4892 5.8636 4.3929 10.6939
NCI-H727 GDSC1; CTRP2 4.4901 6.3702 4.2492 11.2139
HCC15 GDSC1; CTRP2 4.5107 6.0713 4.3633 10.7342
NCI-H1355 GDSC1; CTRP2 4.5177 6.2328 4.3232 10.8591
HCC2108 CTRP2 4.5461 9.6902 2.2942 13.4035
RERF-LC-A1 CTRP2 4.5612 7.2332 3.9967 11.9777
NCI-H2291 GDSC1; CTRP2 4.5697 5.7517 4.5044 10.0488
NCI-H1944 GDSC1; CTRP2 4.5875 8.3013 3.5526 13.6692
NCI-H292 GDSC1; CTRP2 4.6031 5.4839 4.5817 9.6742
DMS 114 GDSC1; CTRP2 4.6104 5.6858 4.5607 9.7231
NCI-H1092 GDSC1; CTRP2 4.6121 6.5512 4.3185 10.601
NCI-H522 GDSC1; CTRP2 4.6215 5.8274 4.5449 9.7437
CPC-N GDSC1 4.6215 7.1424 3.1529 8.1803
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 4.6271 5.7668 4.5636 9.6602
LC-1/sq GDSC1 4.6418 6.5796 3.4474 5.8211
NCI-H2444 GDSC1; CTRP2 4.6596 5.2979 4.5357 3.2356
HCC1438 CTRP2 4.6655 6.1141 4.52 9.6976
NCI-H1435 GDSC1; CTRP2 4.6783 5.8055 4.6113 9.3314
NCI-H1693 GDSC1 4.6851 6.9972 3.2735 7.0383
NCI-H1568 GDSC1; CTRP2 4.6941 6.0775 4.5616 9.4601
HCC78 GDSC1; CTRP2 4.7131 5.6485 4.6773 8.991
NCI-H1373 CTRP2 4.7196 5.7292 4.6708 8.9928
NCI-H526 GDSC1; CTRP2 4.7236 6.1451 4.5743 9.3255
Lu-99 CTRP2 4.7241 5.5535 4.7019 8.8709
LOU-NH91 GDSC1; CTRP2 4.7303 6.1212 4.5886 9.2533
EKVX GDSC1; CTRP2 4.7523 6.2139 4.5846 9.202
HCC1833 CTRP2 4.7602 13.51 0.5725 19.843
PC-14 GDSC1; CTRP2 4.7619 6.9456 4.3261 10.1537
NCI-H1105 CTRP2 4.7777 7.9235 3.9159 11.7348
NCI-H2172 GDSC1; CTRP2 4.7937 7.4646 4.1381 10.8072
A-549 GDSC1; CTRP2 4.8017 5.9931 4.7019 8.6266
Sq-1 CTRP2 4.8061 5.5683 4.787 8.3142
NCI-H650 GDSC1; CTRP2 4.8093 6.4371 4.572 9.0816
NCI-H1792 GDSC1; CTRP2 4.8138 6.3592 4.6039 8.9497
NCI-H1836 GDSC1 4.8157 6.3976 3.6612 3.6707
NCI-H322M GDSC1 4.8429 6.4997 3.6307 3.8288
HCC2935 CTRP2 4.8548 5.7455 4.8139 8.0648
COLO 668 GDSC1; CTRP2 4.8616 6.4866 4.6106 8.7868
NCI-H2009 GDSC1; CTRP2 4.8809 5.9371 4.8022 8.0244
DMS 79 GDSC1 4.8975 7.896 2.9889 8.5714
NCI-H1869 GDSC1; CTRP2 4.9017 6.5685 4.6232 8.6252
NCI-H2085 GDSC1; CTRP2 4.9048 6.2039 4.7538 8.1271
HCC1171 CTRP2 4.9174 8.5307 3.7711 11.9765
NCI-H1651 GDSC1; CTRP2 4.9231 6.0715 4.8132 7.8554
NCI-H1793 GDSC1; CTRP2 4.9544 6.2871 4.7807 7.8816
NCI-H1770 GDSC1 4.9593 6.6068 3.657 3.3353
NCI-H1650 GDSC1; CTRP2 4.9757 6.1209 4.8563 7.5401
LK2 CTRP2 4.9791 5.6908 4.9558 7.176
NCI-H2029 GDSC1; CTRP2 4.9854 6.2837 4.8155 7.6615
Lu-134-A GDSC1 4.9953 8.486 2.7709 9.9148
BEN GDSC1; CTRP2 5.013 6.1891 4.8762 7.3557
HOP-92 GDSC1; CTRP2 5.0208 6.5318 4.7646 7.7516
RERF-LC-KJ GDSC1 5.0258 6.5807 3.7113 2.7837
HCC366 CTRP2 5.0506 6.7403 4.7139 7.8643
NCI-H358 GDSC1; CTRP2 5.0539 6.2859 4.889 7.1885
RERF-LC-Ad1 CTRP2 5.0661 5.9045 5.0114 6.7062
Calu-6 GDSC1; CTRP2 5.0665 6.2442 4.9166 7.0489
EPLC-272H GDSC1; CTRP2 5.0822 6.3663 4.8917 7.0962
NCI-H2342 GDSC1; CTRP2 5.0949 6.2994 4.9288 6.9209
RERF-LC-MS GDSC1; CTRP2 5.1042 5.8374 5.0665 6.3926
CAL-12T GDSC1; CTRP2 5.1113 6.6091 4.8309 7.2457
VMRC-LCD CTRP2 5.1114 6.3066 4.9441 6.8156
NCI-H2110 GDSC1; CTRP2 5.1131 7.2495 4.5593 8.3086
NCI-H2803 GDSC1 5.1372 7.4753 3.3619 5.0743
NCI-H1915 GDSC1; CTRP2 5.1682 6.5253 4.9244 6.7291
T3M-10 CTRP2 5.1831 9.7477 3.4337 12.7424
LCLC-103H GDSC1; CTRP2 5.1926 6.2134 5.0637 6.1336
NCI-H23 GDSC1; CTRP2 5.2103 6.4273 5.0069 6.2963
NCI-H748 GDSC1 5.2209 7.8066 3.2598 5.6177
ChaGo-K-1 GDSC1; CTRP2 5.2271 6.5187 4.9895 6.3158
NCI-H1755 GDSC1; CTRP2 5.2283 6.2385 5.0941 5.9164
NCI-H441 GDSC1; CTRP2 5.2296 6.181 5.1144 5.8375
LUDLU-1 CTRP2 5.2444 6.6012 4.9748 6.3249
SBC-5 GDSC1; CTRP2 5.2735 5.9476 5.2274 5.2954
NCI-H196 GDSC1; CTRP2 5.297 6.0654 5.2229 5.2389
NCI-H322 CTRP2 5.3025 7.2924 4.73 7.146
RERF-LC-Ad2 CTRP2 5.3079 8.333 4.2404 9.1351
NCI-H1339 CTRP2 5.3116 10.3177 3.2701 13.1287
LC-1/sq-SF CTRP2 5.3144 6.0407 5.2488 5.0927
A-427 GDSC1 5.3313 7.9532 3.2628 5.3188
NCI-H209 GDSC1 5.3414 7.0775 3.6724 2.4011
NCI-H1623 GDSC1; CTRP2 5.3965 8.4217 4.2804 8.7673
NCI-H226 GDSC1; CTRP2 5.4021 6.1503 5.3119 4.5992
Lu-65 GDSC1; CTRP2 5.4085 6.4953 5.1907 5.0411
NCI-H2869 GDSC1 5.4219 7.7452 3.417 3.9971
NCI-H1876 GDSC1 5.4271 8.0264 3.2898 4.8937
NCI-H1299 GDSC1; CTRP2 5.4413 6.4161 5.2574 4.6935
Calu-1 CTRP2 5.457 6.5964 5.1991 4.8781
NCI-H2286 CTRP2 5.4638 6.195 5.3641 4.2247
NCI-H82 GDSC1 5.4785 7.1728 3.7058 1.9418
NCI-H460 GDSC1; CTRP2 5.4855 6.2185 5.3794 4.1047
COR-L88 GDSC1 5.4955 12.0803 1.372 17.6302
NCI-H345 GDSC1 5.4991 6.6403 3.9357 0.6403
SW1573 GDSC1; CTRP2 5.5055 10.0033 3.5997 11.3543
NCI-H1395 CTRP2 5.5391 6.4253 5.3568 4.0417
IA-LM GDSC1; CTRP2 5.5871 6.7903 5.245 4.3613
COR-L105 GDSC1; CTRP2 5.6028 8.1491 4.6046 6.9619
NCI-H513 GDSC1 5.6315 8.1308 3.3665 3.9028
HCC1195 CTRP2 5.6317 6.3059 5.503 3.2225
KNS-62 CTRP2 5.6492 7.3696 5.0292 5.0967
Lu-99A GDSC1 5.6806 8.633 3.166 5.1953
NCI-H2369 GDSC1 5.7379 8.6421 3.1968 4.8538
NCI-H2030 GDSC1; CTRP2 5.7961 8.647 3.8246 4.1197
NCI-H838 GDSC1; CTRP2 5.8071 9.1421 4.2936 7.8296
NCI-H720 GDSC1 5.8081 7.7988 3.6101 2.0067
NCI-H3255 GDSC1 5.8963 9.1068 3.0795 5.3253
NCI-H510A GDSC1 6.0038 7.882 3.6717 1.398
NCI-H1781 GDSC1 6.0248 7.3833 3.874 0.4769
NCI-H2347 GDSC1 6.0701 8.4136 3.4838 2.3645
NCI-H2170 GDSC1; CTRP2 6.1396 9.3487 4.4709 6.4324
NCI-H2818 GDSC1 6.2775 9.5422 3.1051 4.3896
NCI-H1993 GDSC1 6.5818 9.0213 3.4821 1.7026
SBC-1 GDSC1 6.6207 8.0894 3.848 0.2639
HCC2279 CTRP2 6.8267 17.2692 0.3463 16.544
NCI-H2373 GDSC1 6.8351 8.4708 3.7933 0.3128
NCI-H2595 GDSC1 7.1209 8.9707 3.7234 0.372
NCI-H2461 GDSC1 7.1653 9.07 3.7049 0.4002
Hs 888.Lu CTRP2 5.129 7.3763 4.5181 8.4327
⏷ Show the Full List of 210 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 3.6711 5.272 3.2353 11.2602
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 1.6088 8.3901 0.4088 33.2761
TOV-21G GDSC1 2.9463 4.0833 2.8784 17.6335
TYK-nu GDSC1; CTRP2 3.5824 5.0489 3.5499 16.5118
A2780 GDSC1; CTRP2 3.6863 5.5399 3.589 16.0432
SNU-119 CTRP2 3.7076 5.2861 3.6541 15.7496
OV-90 GDSC1; CTRP2 3.9033 8.1716 2.9138 17.9586
ES-2 GDSC1 4.007 4.6522 3.8539 5.0173
OAW28 GDSC1; CTRP2 4.0472 5.5112 3.9838 13.5217
Caov-4 GDSC1 4.0992 5.2368 3.6678 6.0268
OVK18 GDSC1; CTRP2 4.1317 5.8099 4.016 13.1425
OVKATE GDSC1 4.1578 5.1284 3.7749 4.948
COV362 CTRP2 4.1645 8.4173 3.0734 16.6499
OC 314 GDSC1; CTRP2 4.2774 4.9216 4.276 11.7767
OVCAR-5 GDSC1; CTRP2 4.2945 5.7525 4.2058 11.9634
DOV13 GDSC1; CTRP2 4.4069 5.7996 4.0589 5.9606
Kuramochi GDSC1; CTRP2 4.4303 6.2504 4.2226 11.4885
RMG-I GDSC1; CTRP2 4.4545 5.5054 4.4213 10.7048
MCAS CTRP2 4.4942 6.2734 4.285 11.0693
Caov-3 GDSC1; CTRP2 4.5752 5.4108 4.5596 9.8407
SNU-8 CTRP2 4.6016 5.074 4.6011 9.6138
OVSAHO CTRP2 4.645 5.8703 4.561 9.6131
OVTOKO GDSC1; CTRP2 4.6513 5.5685 4.6226 9.3782
COV644 CTRP2 4.6599 5.9683 4.5536 9.5934
JHOS-2 GDSC1; CTRP2 4.6978 5.4738 4.6825 9.0228
OV7 CTRP2 4.7437 5.6994 4.702 8.8078
OVCAR-4 GDSC1; CTRP2 4.7687 5.9546 4.6757 8.8219
OVISE GDSC1; CTRP2 4.8692 5.6062 4.6068 2.3657
OVCAR-8 GDSC1; CTRP2 4.8695 6.1421 4.7342 8.3041
IGROV-1 GDSC1; CTRP2 4.8778 6.2399 4.7129 8.3579
ONCO-DG-1 CTRP2 4.901 5.8233 4.8493 7.7949
TOV-112D GDSC1; CTRP2 4.9234 6.6215 4.6262 8.5528
ES2 CTRP2 5.1937 6.457 4.9779 6.4531
OV56 GDSC1; CTRP2 5.2316 6.0396 5.1587 5.6698
SNU-840 CTRP2 5.2385 8.0227 4.3234 8.9559
HEY A8 CTRP2 5.3465 6.5139 5.1179 5.4921
FU-OV-1 GDSC1; CTRP2 5.3995 7.3243 4.8109 6.5805
JHOC-5 CTRP2 5.4218 6.0644 5.3594 4.3665
SK-OV-3 GDSC1; CTRP2 5.4241 6.2931 5.2863 4.6312
JHOM-1 CTRP2 5.4563 6.06 5.3982 4.1217
EFO-21 GDSC1; CTRP2 5.4742 10.4489 3.3506 12.448
EFO-27 GDSC1; CTRP2 5.5178 10.7367 3.2461 12.784
OAW42 GDSC1; CTRP2 5.5474 5.9313 5.5282 3.3768
OVCAR-3 GDSC1 6.8893 8.395 3.8389 0.1998
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 3.9554 5.4961 3.8875 14.1491
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 4.2445 5.4636 4.2028 12.1328
Yamato-SS CTRP2 4.4975 5.2491 4.4902 10.3301
A-204 GDSC1; CTRP2 -0.7349 5.8701 -1.3072 45.9064
G-402 GDSC1; CTRP2 0.7623 7.1474 -0.055 37.4342
Rh18 CTRP2 3.5234 4.8983 3.5015 16.869
G-401 GDSC1; CTRP2 3.7045 6.3092 3.4138 16.6161
EW-8 GDSC1 3.7507 4.4523 3.6586 7.7579
Hs 633.T GDSC1 3.8065 4.2713 3.7724 6.664
Rh41 GDSC1; CTRP2 3.961 5.0045 3.9493 13.9192
VA-ES-BJ GDSC1 3.9666 4.5593 3.8508 5.2424
Rh30 GDSC1 3.9828 4.7941 3.7661 5.7897
KYM-1 GDSC1; CTRP2 4.21 4.8884 4.2084 12.2262
BT-16 CTRP2 4.2385 5.1358 4.2288 12.0634
GCT GDSC1; CTRP2 4.5016 5.3763 4.4854 10.3327
SW872 GDSC1 4.5616 5.7651 3.789 3.4109
Hs 729.T CTRP2 4.6804 6.7977 4.299 10.4827
HT-1080 GDSC1; CTRP2 4.6969 5.6071 4.6661 9.0818
RD GDSC1; CTRP2 4.7051 6.0953 4.5686 9.4018
SW684 GDSC1 4.7688 6.6522 3.505 4.9933
RKN GDSC1; CTRP2 4.8065 5.8666 4.7375 8.4852
TE 617.T CTRP2 4.8779 5.8871 4.8107 8.0034
SK-UT-1 GDSC1; CTRP2 4.9082 6.2584 4.74 8.168
SW982 GDSC1; CTRP2 4.9572 5.9233 4.8886 7.4805
SK-LMS-1 GDSC1; CTRP2 5.2571 6.2629 5.1169 5.7476
MES-SA GDSC1; CTRP2 5.3421 6.053 5.2756 4.9115
TE 441.T GDSC1; CTRP2 5.404 6.5707 5.1549 5.1926
MFH-ino GDSC1 5.5396 7.7243 3.4964 3.2011
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; CTRP2 4.4589 6.1181 4.2934 11.1441
NCI-H2052 GDSC1; CTRP2 4.6811 5.9087 4.5913 9.3937
NCI-H2452 GDSC1; CTRP2 5.0174 6.9444 4.0718 4.4359
ACC-MESO-1 CTRP2 5.1333 6.8398 4.7592 7.4647
NCI-H28 GDSC1; CTRP2 5.1446 6.361 4.9609 6.6569
JL-1 CTRP2 5.2209 5.8319 5.1935 5.5796
IST-Mes1 GDSC1; CTRP2 5.349 8.5781 4.1598 9.3739
MPP 89 GDSC1 6.1222 7.7424 3.7794 0.7691
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1 4.1587 5.2508 3.7153 5.4099
LNCaP clone FGC GDSC1; CTRP2 4.4474 8.2638 3.4289 14.5177
22Rv1 GDSC1; CTRP2 4.4882 5.882 4.3875 10.7165
VCaP GDSC1; CTRP2 4.6714 5.6208 4.6368 9.2645
DU145 GDSC1; CTRP2 5.2903 6.2769 5.148 5.5354
PaCa-3 CTRP2 5.5965 17.1763 0.101 23.7123
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 4.5906 5.9427 4.4844 10.0543
A-253 GDSC1; CTRP2 5.158 6.4143 4.9558 6.6381
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 3.7284 4.4172 3.6459 7.9688
Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 GDSC1; CTRP2 3.134 3.9949 3.1336 19.3909
HSC-39 GDSC1 3.1815 4.5291 3.0152 15.365
Fu97 GDSC1; CTRP2 3.2162 4.963 3.1721 18.9905
HGC-27 GDSC1; CTRP2 3.2591 4.7576 3.2365 18.6322
GSS CTRP2 3.2829 4.492 3.2756 18.4218
NCC-StC-K140 CTRP2 3.5332 5.8708 3.3493 17.3689
SNU-620 CTRP2 3.8204 4.6675 3.818 14.8247
GCIY GDSC1 3.8425 4.4981 3.7419 6.6739
SNU-1 GDSC1; CTRP2 3.9999 5.5701 3.9224 13.8858
RF-48 GDSC1 4.0217 5.0792 3.6711 6.3348
SNU-16 GDSC1; CTRP2 4.0906 4.945 4.0855 13.0334
SNU-5 GDSC1; CTRP2 4.1354 5.0721 4.1258 12.7501
NCI-N87 GDSC1; CTRP2 4.1827 5.3558 4.151 12.5099
IM95 GDSC1; CTRP2 4.2683 5.4311 4.2326 11.9538
RERF-GC-1B GDSC1 4.2771 12.7709 0.06 27.9662
KE-39 CTRP2 4.359 6.6717 4.0024 12.5165
SNU-601 CTRP2 4.3603 5.7087 4.2861 11.4744
23132/87 GDSC1; CTRP2 4.4126 5.3216 4.3969 10.924
SNU-668 CTRP2 4.5718 5.5845 4.5355 9.9339
SNU-719 CTRP2 4.6548 5.7965 4.3092 4.2156
NUGC-4 GDSC1; CTRP2 4.6558 5.6219 4.6199 9.3729
NUGC-3 GDSC1; CTRP2 4.6703 5.4583 4.655 9.2059
MKN28 GDSC1 4.7477 6.9328 3.3521 6.2353
SNU-216 CTRP2 4.8323 6.1761 4.6835 8.6008
AGS GDSC1; CTRP2 4.8867 6.3034 4.2791 3.7867
GSU CTRP2 4.8871 5.2426 4.8868 7.7111
MKN74 CTRP2 4.8941 6.9747 4.4528 9.3031
ECC12 CTRP2 5.0082 5.9614 4.9352 7.1567
MKN1 GDSC1; CTRP2 5.0176 6.1859 4.8823 7.32
Hs 746.T GDSC1; CTRP2 5.0553 5.8862 5.0037 6.7671
SCH GDSC1 5.1226 7.4795 3.3502 5.1994
MKN7 GDSC1; CTRP2 5.1363 6.8529 4.7568 7.4661
TGBC11TKB GDSC1 5.3055 7.7017 3.3645 4.6394
HuG1-N CTRP2 5.4271 12.7508 2.1639 17.2493
SH-10-TC CTRP2 5.5057 5.9419 5.481 3.6735
OCUM-1 GDSC1 5.5355 8.4805 3.1461 5.6723
TMK-1 GDSC1 5.6179 7.6274 3.5834 2.481
MKN45 GDSC1; CTRP2 5.9919 6.7739 5.635 1.8249
LMSU CTRP2 6.4951 17.189 0.8431 19.6832
SNG-M GDSC1; CTRP2 3.6165 5.1234 3.5778 16.3056
SNU-1077 CTRP2 5.0207 8.1012 4.0746 10.493
SNU-685 CTRP2 5.0806 6.0508 4.9908 6.7353
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 -0.7658 5.6399 -1.2813 46.0309
CGTH-W-1 GDSC1; CTRP2 3.359 12.3638 0.4399 27.9931
K5 GDSC1 3.8307 4.6079 3.6876 7.1246
KMH-2 GDSC1 3.8771 4.8823 3.6194 7.3953
IHH-4 GDSC1 3.9644 4.6188 3.8241 5.4485
8505C GDSC1; CTRP2 4.0195 5.3882 3.973 13.6478
TT GDSC1; CTRP2 4.0655 5.3749 4.0239 13.3245
8305C GDSC1; CTRP2 4.0857 4.8197 4.0838 13.0557
HTC-C3 GDSC1 4.1204 5.286 3.6631 5.975
BHT-101 GDSC1; CTRP2 4.3032 5.0913 4.2977 11.6186
B-CPAP GDSC1; CTRP2 4.3126 5.0827 4.3076 11.554
FTC-238 CTRP2 4.8447 6.2192 4.6835 8.5639
CAL-62 GDSC1; CTRP2 4.8539 5.4899 4.8446 7.9623
FTC-133 GDSC1; CTRP2 4.8566 6.386 4.641 8.6868
ML-1 [Human leukemia] GDSC1; CTRP2 5.1744 6.2385 5.0356 6.2913
TT2609-C02 GDSC1; CTRP2 5.5556 6.6126 5.2935 4.2469
ASH-3 GDSC1 5.7115 7.4877 3.6922 1.6659
WRO GDSC1 6.4818 7.9685 3.8391 0.3406
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHU-011 GDSC1 2.6435 4.4656 2.4491 22.2613
Detroit 562 GDSC1; CTRP2 3.8446 5.3967 3.7845 14.86
BB30-HNC GDSC1 3.8757 4.4322 3.8009 6.0794
SCC-25 GDSC1; CTRP2 3.8772 4.7292 3.8743 14.4478
YD-10B CTRP2 3.9006 5.2023 3.8696 14.3869
SNU-1214 CTRP2 3.9113 5.5793 3.8249 14.5069
OSC-20 GDSC1 3.9171 4.9123 3.6463 7.0024
YD-8 CTRP2 3.9196 5.2299 3.8868 14.2665
PCI-04B GDSC1 4.0213 5.0819 3.6695 6.3489
NCI-H3118 GDSC1 4.0455 5.0752 3.6958 6.0393
PCI-15A GDSC1 4.0522 4.9023 3.7848 5.3256
HSC-3 GDSC1; CTRP2 4.088 4.9345 4.0833 13.0495
JHU-022 GDSC1 4.1062 5.0173 3.7814 5.1145
BHY GDSC1; CTRP2 4.1963 5.275 4.1741 12.3872
SKN-3 GDSC1 4.2802 5.4167 3.7394 4.7476
CAL-27 GDSC1; CTRP2 4.358 5.7835 4.2681 11.5449
SCC-15 GDSC1 4.3608 5.9086 3.5608 5.8637
CAL-33 GDSC1; CTRP2 4.4177 5.5105 4.3813 10.9609
SNU-899 CTRP2 4.4198 5.3666 4.4004 10.8887
BICR 31 GDSC1; CTRP2 4.4372 6.2925 4.2169 11.4889
BICR 10 GDSC1 4.519 5.7994 3.7403 3.921
LB771-HNC GDSC1 4.5191 6.1042 3.5893 5.1025
SAS GDSC1 4.5621 6.5544 3.399 6.4531
PCI-38 GDSC1 4.5883 6.9088 3.2432 7.5849
PE/CA-PJ49 CTRP2 4.6429 5.9194 4.5471 9.6691
HSC-4 GDSC1; CTRP2 4.6595 5.5702 4.6312 9.3223
PCI-06A GDSC1 4.6691 6.3961 3.558 4.8779
SNU-1066 CTRP2 4.7002 6.1259 4.5544 9.4678
SCC-4 GDSC1; CTRP2 4.7195 5.3931 4.7115 8.8535
SNU-1076 CTRP2 4.7235 5.465 4.7103 8.8444
SNU-46 CTRP2 4.8453 5.7692 4.7994 8.1457
BICR 22 GDSC1; CTRP2 4.9548 5.8212 4.9079 7.4199
PE/CA-PJ15 GDSC1; CTRP2 4.9913 5.9108 4.9286 7.2325
BICR 18 CTRP2 5.0385 9.1448 3.5928 12.4193
HSC-2 GDSC1; CTRP2 5.1768 9.7632 3.4203 12.8113
OSC-19 GDSC1 5.218 6.9482 3.6591 2.7361
BICR 16 CTRP2 5.2182 6.9848 4.7842 7.1429
HO-1-u-1 GDSC1 5.2379 7.5847 3.3762 4.7175
FaDu GDSC1; CTRP2 5.2394 5.9963 5.1785 5.5749
DOK GDSC1 5.2469 7.5136 3.4154 4.4097
PE/CA-PJ34 (clone C12) CTRP2 5.2566 9.4183 3.663 11.6348
SCC-9 GDSC1; CTRP2 5.3024 6.5385 5.0614 5.8317
BICR 6 CTRP2 5.3118 5.8077 5.2949 4.9378
SNU-1041 CTRP2 5.3377 6.674 5.0422 5.811
PE/CA-PJ41 (clone D2) CTRP2 5.4483 14.1763 1.4716 19.71
BICR 78 GDSC1 5.6597 8.3803 3.2695 4.5157
Ca9-22 GDSC1 5.6726 8.3677 3.2831 4.3939
KON GDSC1 5.8739 8.1481 3.495 2.6058
PCI-30 GDSC1 6.1481 8.6871 3.4078 2.7013
KOSC-2 GDSC1 6.2457 8.381 3.5834 1.5714
HO-1-N-1 GDSC1 6.2477 7.8517 3.7903 0.6301
BB49-HNC GDSC1 6.9674 9.4514 3.4852 1.2983
BICR 56 CTRP2 7.5057 10.7894 4.7509 3.1789
SAT [Human HNSCC] GDSC1 7.9342 10.31 3.5535 0.47
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-BLC1 CTRP2 3.381 4.9653 3.346 17.8619
VM-CUB-1 CTRP2 3.9096 5.4047 3.8529 14.415
TCCSUP GDSC1; CTRP2 3.9245 4.9312 3.9156 14.1526
253J CTRP2 3.983 4.7987 3.9802 13.7427
RT-112 GDSC1; CTRP2 4.1633 5.4348 4.1201 12.6789
UM-UC-1 CTRP2 4.1754 7.2276 3.593 14.5925
CAL-29 GDSC1; CTRP2 4.2649 5.398 4.2332 11.9625
BFTC-905 GDSC1; CTRP2 4.3949 5.2443 4.3842 11.025
JMSU-1 CTRP2 4.4104 5.3182 4.3948 10.9383
KMBC-2 CTRP2 4.4793 5.8766 4.379 10.7742
RT-4 GDSC1; CTRP2 4.5463 6.2545 4.3476 10.6845
SW1710 GDSC1; CTRP2 4.551 6.7158 4.1922 11.2527
5637 GDSC1; CTRP2 4.629 6.1662 4.1084 5.1606
647V GDSC1; CTRP2 4.7946 5.8689 4.724 8.57
J82 GDSC1; CTRP2 4.8123 6.2273 4.6457 8.7992
253J-BV CTRP2 4.8187 6.0799 4.6969 8.5931
639V GDSC1; CTRP2 4.8336 5.3338 4.8314 8.0737
UM-UC-3 GDSC1; CTRP2 4.8583 6.4353 4.6255 8.7399
BC-3C CTRP2 4.9149 5.8091 4.8671 7.689
HT-1376 GDSC1; CTRP2 5.2176 6.5633 4.9618 6.4486
SCaBER CTRP2 5.2392 8.2671 4.207 9.4318
HT-1197 GDSC1; CTRP2 5.254 6.0332 5.1849 5.5071
T24 GDSC1; CTRP2 5.3727 6.7634 5.0398 5.7278
KU-19-19 GDSC1; CTRP2 5.4363 5.9827 5.3965 4.1889
SW780 GDSC1 5.7177 7.4958 3.6919 1.6587
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BPH-1 GDSC1 2.3542 8.5694 0.3971 34.9426
Ca Ski GDSC1 3.2561 6.3341 2.3317 19.9132
OV17R GDSC1 3.3288 6.0929 2.5159 18.2421
HEY GDSC1 3.6787 4.9668 3.3789 10.1505
KGN GDSC1 3.8087 4.6482 3.6483 7.5225
SW954 GDSC1 3.82 4.4958 3.7185 6.9609
PA-1 GDSC1 3.8397 4.6608 3.6758 7.1635
JAR GDSC1 3.8567 4.7742 3.646 7.2969
NT2-D1 GDSC1 3.8908 4.531 3.7815 6.1358
ACC-OV7 GDSC1 3.9099 4.9823 3.6071 7.3319
SKN GDSC1 3.9429 5.518 3.3847 8.8894
C-33 A GDSC1 3.9522 4.8947 3.6895 6.5106
ME-180 GDSC1 3.9571 5.5535 3.3808 8.8578
NEC8 GDSC1 4.0033 4.6386 3.856 5.0194
NCC-IT GDSC1 4.0196 4.6629 3.8621 4.8942
JEG-3 GDSC1 4.209 5.0636 3.8533 4.1265
CAL-39 GDSC1 4.2265 5.46 3.6715 5.4858
DSH1 GDSC1 4.3624 5.8679 3.5824 5.6875
OMC-1 [Human cervical carcinoma] GDSC1 4.5134 6.0074 3.6329 4.779
OVMIU GDSC1 4.5218 6.335 3.4767 5.9756
LB831-BLC GDSC1 4.5262 5.8092 3.7409 3.8939
OVCA433 GDSC1 4.6642 6.4417 3.532 5.0945
DoTc2 4510 GDSC1 4.8019 6.7055 3.5026 4.9162
OVCA420 GDSC1 4.8392 6.7232 3.5203 4.6757
HeLa GDSC1; CTRP2 4.8429 5.5451 4.8284 8.0533
HT-3 GDSC1 4.8706 7.1836 3.3186 6.1295
MS751 GDSC1 4.9391 6.8505 3.5276 4.3501
SW756 GDSC1 5.3817 7.8937 3.3231 4.7597
SiHa GDSC1 5.4375 6.7816 3.8504 1.1443
JHOS-3 GDSC1 5.4861 7.3664 3.6255 2.4427
C-4-I GDSC1 5.5202 8.1586 3.2865 4.7031
PEO1 GDSC1 5.5697 11.0873 1.9143 14.1383
SiSo GDSC1 5.6416 8.1749 3.3525 3.9787
HEC-1 GDSC1 5.8019 7.5464 3.7124 1.4302
SKG-IIIa GDSC1 5.8238 8.0522 3.5097 2.5966
SW962 GDSC1 6.2961 8.478 3.5678 1.5928
UWB1.289 GDSC1 6.8149 9.5505 3.3776 1.9676
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 Cytochromes P450 2C8 and 3A Catalyze the Metabolic Activation of the Tyrosine Kinase Inhibitor Masitinib. Chem Res Toxicol. 2022 Sep 19;35(9):1467-1481. doi: 10.1021/acs.chemrestox.2c00057. Epub 2022 Sep 1.
5 Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT. PLoS One. 2009 Sep 30;4(9):e7258. doi: 10.1371/journal.pone.0007258.
6 Additive cell protective and oxidative stress reducing effects of combined treatment with cromolyn sodium and masitinib on MPTP-induced toxicity in SH-SY5Y neuroblastoma cells. Chem Biol Interact. 2022 Feb 25;354:109808. doi: 10.1016/j.cbi.2022.109808. Epub 2022 Jan 7.