Details of the Drug

General Information of Drug (ID: DMS20X6)

Drug Name
CDX-1135
Synonyms SCR1; BRL-55730; Soluble complement receptor type 1, AVANT; Soluble complement receptor type 1, Celldex; YM-203; TP-10, AVANT Immunotherapeutics; TP-10, Celldex
Indication
Disease Entry ICD 11 Status REF
Macular degeneration 9B78.3 Phase 1 [1]
Cross-matching ID
UNII
2RF4H67MOG
DrugBank ID
DB17607
TTD ID
D0T4NV

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement receptor type 1 (CR1) TTEA8OW CR1_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01791686) Clinical Trial of CDX-1135 in Pediatric and Adult Patients With Dense Deposit Disease. U.S. National Institutes of Health.
2 Complement activation is critical for placental ischemia-induced hypertension in the rat. Mol Immunol. 2013 Nov;56(1-2):91-7.