Details of the Drug

General Information of Drug (ID: DMSF4UI)

Drug Name
MDT-006
Synonyms
EPX-16006; Chronic constipation, IBS-C therapy (PolyCap), MicroDose Therapeutx; P2Y2 agonist (oral, constipation/irritable bowel syndrome), EPIX; Purinoceptor P2Y2 agonist (oral, constipation/IBS), EPIX
Indication
Disease Entry ICD 11 Status REF
Constipation DD91.1 Investigative [1]
Cross-matching ID
TTD ID
D09CLX

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
P2Y purinoceptor 2 (P2RY2) TTOZHQC P2RY2_HUMAN Agonist [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Constipation
ICD Disease Classification DD91.1
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
P2Y purinoceptor 2 (P2RY2) DTT P2RY2 7.03E-10 0.14 0.52
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 324).