Details of the Drug

General Information of Drug (ID: DMSHE70)

Drug Name
GSK2141795
Synonyms
Uprosertib; 1047634-65-0; GSK2141795; UNII-ZXM835LQ5E; Uprosertib (GSK2141795); GSK2141795C; ZXM835LQ5E; GSK795; GSK-2141795; 2-Furancarboxamide, N-[(1S)-2-amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-;2-Furancarboxamide, N-[(1S)-2-amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-; Uprosertib [USAN:INN]; Uprosertib (USAN/INN); Uprosertib, GSK2141795; SCHEMBL168584; GTPL7902; CHEMBL3137336; MolPort-044-560-307; AXTAPYRUEKNRBA-JTQLQIEISA-N
Indication
Disease Entry ICD 11 Status REF
Colorectal cancer 2B91.Z Phase 2 [1]
Lymphoma 2A80-2A86 Phase 2 [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 429.2
Logarithm of the Partition Coefficient (xlogp) 3.4
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C18H16Cl2F2N4O2
IUPAC Name
N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methylpyrazol-3-yl)furan-2-carboxamide
Canonical SMILES
CN1C(=C(C=N1)Cl)C2=C(OC(=C2)C(=O)N[C@@H](CC3=CC(=C(C=C3)F)F)CN)Cl
InChI
InChI=1S/C18H16Cl2F2N4O2/c1-26-16(12(19)8-24-26)11-6-15(28-17(11)20)18(27)25-10(7-23)4-9-2-3-13(21)14(22)5-9/h2-3,5-6,8,10H,4,7,23H2,1H3,(H,25,27)/t10-/m0/s1
InChIKey
AXTAPYRUEKNRBA-JTQLQIEISA-N
Cross-matching ID
PubChem CID
51042438
CAS Number
1047634-65-0
UNII
ZXM835LQ5E
DrugBank ID
DB11969
TTD ID
D01NEC
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
RAC-gamma serine/threonine-protein kinase (AKT3) TTAZ05C AKT3_HUMAN Modulator [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Post-Translational Modifications [3]
Glycogen synthase kinase-3 beta (GSK3B) OTL3L14B GSK3B_HUMAN Post-Translational Modifications [3]
Proline-rich AKT1 substrate 1 (AKT1S1) OT4JHN4Y AKTS1_HUMAN Post-Translational Modifications [3]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Gene/Protein Processing [3]
RAC-beta serine/threonine-protein kinase (AKT2) OTBB632K AKT2_HUMAN Gene/Protein Processing [3]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Protein Interaction/Cellular Processes [4]
Tumor necrosis factor receptor superfamily member 6 (FAS) OTP9XG86 TNR6_HUMAN Protein Interaction/Cellular Processes [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Colorectal cancer
ICD Disease Classification 2B91.Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
RAC-gamma serine/threonine-protein kinase (AKT3) DTT AKT3 6.79E-01 -0.02 -0.08
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 3.428 6.5177 1.8115 9.2483
ES1 GDSC2 0.6732 3.9054 0.2532 28.736
EW-22 GDSC2 1.0897 8.3484 -1.2291 32.99
EW-12 GDSC2 1.5628 6.3151 0.1897 25.1352
EW-11 GDSC2 1.5866 9.3131 -1.2194 30.9861
EW-7 GDSC2 1.6799 6.0174 0.4436 23.3465
ES5 GDSC2 1.7908 6.9569 0.1112 24.6222
ES8 GDSC2 1.8526 8.3186 -0.4862 27.1506
EW-18 GDSC2 2.0505 7.5317 0.0821 23.7794
EW-24 GDSC2 2.0896 9.0186 -0.6089 26.7939
CHSA0108 GDSC2 2.2187 8.0364 -0.0078 23.606
HuO9 GDSC2 2.5685 12.3092 -1.8141 29.5297
SJSA-1 GDSC2 2.7726 7.5174 0.7505 17.6768
EW-1 GDSC2 2.9939 6.3327 1.5351 12.2778
HOS GDSC2 3.3105 5.8021 2.0723 7.9437
SK-PN-DW GDSC2 3.3456 7.54 1.2326 13.0576
SaOS-2 GDSC2 3.3528 10.2455 -0.1142 20.3911
H-EMC-SS GDSC2 3.4604 11.4926 -0.6486 22.4963
EW-13 GDSC2 3.4667 12.7336 -1.2638 24.9309
CHSA8926 GDSC2 3.4853 6.7037 1.7652 9.3772
HuO-3N1 GDSC2 3.5217 7.272 1.5108 10.8548
EW-3 GDSC2 3.7506 13.0323 -1.1808 23.8129
CHSA0011 GDSC2 3.7847 9.2123 0.7529 14.6079
ES7 GDSC2 3.9183 8.3557 1.2831 11.1674
ES6 GDSC2 4.0372 13.2663 -1.0675 22.5891
CAL-78 GDSC2 4.121 8.2673 1.4795 9.4747
TC-71 GDSC2 4.1727 7.8619 1.716 7.9182
SK-ES-1 GDSC2 4.3744 11.5078 0.0696 16.6513
CAL-72 GDSC2 4.6348 8.0565 1.939 5.5825
G-292 clone A141B1 GDSC2 4.7316 8.0302 2.0132 4.9644
EW-16 GDSC2 4.7701 13.9797 -0.8535 19.8378
CADO-ES1 GDSC2 4.8106 7.7027 2.2127 3.6921
ES4 GDSC2 4.8941 9.9349 1.2162 9.2448
NY GDSC2 5.3686 8.521 2.1648 3.0952
U2OS GDSC2 5.7216 12.8609 0.3737 12.0173
U-CH2 GDSC2 5.7591 7.6929 2.6847 0.5372
NOS-1 [Human HNSCC] GDSC2 5.9179 15.438 -0.7327 16.7041
A-673 GDSC2 6.2235 16.957 -1.255 18.1521
MHH-ES-1 GDSC2 6.5637 14.2 0.2888 10.7999
MG-63 GDSC2 7.1971 22.1545 -3.0928 22.2324
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 165 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC2 4.7298 8.8472 1.6261 7.2241
WSU-DLCL2 GDSC2 -5.5347 -4.7103 -5.5347 88.6857
NCI-H929 GDSC2 -3.8894 -1.7557 -3.8906 71.8167
SU-DHL-6 GDSC2 -3.2257 -1.4739 -3.2261 65.5986
MM1.S GDSC2 -2.7052 -1.4513 -2.7052 60.4772
DoHH2 GDSC2 -2.1784 0.3774 -2.1988 55.0504
WSU-NHL GDSC2 -2.0859 -0.2471 -2.0885 54.2453
SU-DHL-16 GDSC2 -1.8837 0.2812 -1.8937 52.2108
Loucy GDSC2 -1.2077 5.2857 -2.2686 46.8794
SU-DHL-5 GDSC2 -0.8956 1.5643 -0.9462 42.5143
Jurkat GDSC2 -0.8439 5.1485 -1.8273 44.0977
SUP-B8 GDSC2 -0.829 1.9673 -0.923 42.0032
A4/Fukuda GDSC2 -0.766 3.6312 -1.2275 42.4338
Farage GDSC2 -0.7046 3.5482 -1.1361 41.8093
SU-DHL-10 GDSC2 -0.6652 0.6306 -0.6666 40.018
SU-DHL-4 GDSC2 -0.5977 1.3089 -0.6164 39.4198
Karpas-620 GDSC2 -0.3179 3.9037 -0.8232 38.5238
NALM-6 GDSC2 -0.2348 5.0242 -1.1283 38.9945
KE-37 GDSC2 0.1237 6.5306 -1.3679 37.7844
RCH-ACV GDSC2 0.1623 3.2107 -0.0965 32.9636
SIG-M5 GDSC2 0.1628 1.0808 0.1624 31.7043
MC116 GDSC2 0.2245 2.9676 0.0314 32.0385
NU-DUL-1 GDSC2 0.2557 5.3983 -0.7543 35.1788
RPMI-8402 GDSC2 0.2812 3.7845 -0.1335 32.5229
MOLP-8 GDSC2 0.4385 4.6964 -0.2838 32.3985
MOLT-16 GDSC2 0.5038 5.6669 -0.6047 33.3917
HT GDSC2 0.5248 7.7605 -1.5106 36.285
P32/ISH GDSC2 0.6632 4.547 0.0133 29.9575
Karpas-45 GDSC2 0.679 4.7551 -0.0498 30.1795
BONNA-12 GDSC2 0.6797 6.3825 -0.7318 33.0423
TALL-1 [Human adult T-ALL] GDSC2 0.6845 4.1862 0.1686 29.1037
OPM-2 GDSC2 0.7176 2.9283 0.5767 26.8599
OCI-Ly7 GDSC2 0.8172 5.0986 -0.0406 29.489
Karpas-422 GDSC2 0.8429 7.8911 -1.2553 34.1186
L-363 GDSC2 0.8818 4.7249 0.1777 28.1371
HAL-01 GDSC2 1.0024 6.4477 -0.4327 30.3937
GA-10 GDSC2 1.0155 5.8718 -0.163 29.1549
ARH-77 GDSC2 1.0276 7.6758 -0.9727 32.3741
KMS-11 GDSC2 1.1397 4.873 0.391 25.8922
PF-382 GDSC2 1.2443 8.2167 -1.0168 31.6266
L-1236 GDSC2 1.2893 5.4595 0.2987 25.7202
MHH-CALL-4 GDSC2 1.4835 6.1893 0.1687 25.5648
P12-Ichikawa GDSC2 1.5068 8.0558 -0.6872 29.3234
CCRF-CEM GDSC2 1.5807 7.4525 -0.3278 27.5158
Ramos.2G6.4C10 GDSC2 1.5883 4.5715 0.9865 20.7172
JVM-2 GDSC2 1.6401 8.4209 -0.7361 28.9946
Hs 445 GDSC2 1.6831 12.847 -2.8669 35.1744
AMO1 GDSC2 1.6845 4.4532 1.136 19.4637
Namalwa GDSC2 1.6903 6.2467 0.3478 23.8106
RPMI-6666 GDSC2 1.7073 8.3241 -0.6257 28.2901
BC-1 GDSC2 1.7443 4.5625 1.1538 19.1138
MOLM-13 GDSC2 1.8248 5.7548 0.709 21.3245
BL-41 GDSC2 1.8431 5.9667 0.6291 21.696
CA46 GDSC2 1.8496 5.8169 0.7051 21.249
GR-ST GDSC2 1.8683 5.57 0.8374 20.4313
Mono-Mac-6 GDSC2 1.9082 8.914 -0.7248 27.9336
TUR GDSC2 1.9219 6.0409 0.6721 21.1527
Kasumi-1 GDSC2 1.9297 6.1573 0.6252 21.3825
697 GDSC2 1.9661 5.9627 0.7522 20.5348
SU-DHL-1 GDSC2 1.9845 19.4325 -5.8733 39.0605
WIL2 NS GDSC2 1.996 7.5612 0.0164 24.3063
U-698-M GDSC2 2.0205 6.9393 0.3402 22.5734
RL GDSC2 2.0225 6.3027 0.6466 20.9105
ML-2 GDSC2 2.0467 5.4503 1.0704 18.3981
THP-1 GDSC2 2.0475 6.9349 0.368 22.3265
ATN-1 GDSC2 2.1634 6.8018 0.5423 20.9603
CRO-AP2 GDSC2 2.2905 5.2789 1.3914 15.575
Reh GDSC2 2.3169 6.4053 0.8794 18.5073
SUP-T1 GDSC2 2.3372 8.6533 -0.2031 24.1153
DEL GDSC2 2.4281 4.7421 1.7769 12.7326
PL-21 GDSC2 2.4601 5.5517 1.4269 14.7419
MV4-11 GDSC2 2.4796 9.6153 -0.5517 25.1826
JVM-3 GDSC2 2.4936 6.2673 1.1126 16.5145
DG-75 GDSC2 2.5443 5.9922 1.294 15.25
ALL-PO GDSC2 2.5568 6.4353 1.0892 16.4338
BALL-1 GDSC2 2.5861 7.779 0.4539 19.9448
EB2 GDSC2 2.6202 8.3518 0.2007 21.1613
MLMA GDSC2 2.6442 6.3252 1.2238 15.3298
Daudi GDSC2 2.6506 5.0938 1.8291 11.6007
NB4 GDSC2 2.6646 7.2969 0.7631 17.9648
ALL-SIL GDSC2 2.6832 5.6654 1.583 13.0053
KY821 GDSC2 2.7829 6.7085 1.1609 15.2435
ST486 GDSC2 2.85 5.2724 1.93 10.286
CESS GDSC2 2.8663 9.4374 -0.1233 21.9522
VAL GDSC2 2.8872 9.3233 -0.0483 21.5229
P30/OHK GDSC2 2.8904 4.7992 2.1987 8.474
MOLM-16 GDSC2 2.8986 5.801 1.7141 11.4718
RPMI-8226 GDSC2 2.9838 6.1132 1.6354 11.6871
Ku812 GDSC2 3.0642 5.9882 1.7684 10.603
BV-173 GDSC2 3.09 7.4024 1.0853 14.7125
SR GDSC2 3.1298 6.4257 1.6071 11.4068
CTB-1 GDSC2 3.1595 6.7662 1.4627 12.2108
JSC-1 GDSC2 3.2218 7.4868 1.1555 13.8901
SUP-HD1 GDSC2 3.2223 5.6777 2.0601 8.2822
JeKo-1 GDSC2 3.2286 8.8662 0.4716 17.7764
MHH-PREB-1 GDSC2 3.2331 5.3063 2.2548 7.0192
HH [Human lymphoma] GDSC2 3.2369 8.2904 0.7665 16.1163
NK-92MI GDSC2 3.2754 7.0467 1.4206 12.1206
Jiyoye GDSC2 3.3185 10.9849 -0.5124 22.3277
SUP-M2 GDSC2 3.3307 5.0743 2.453 5.4761
SKM-1 GDSC2 3.3527 8.9419 0.5376 17.0428
A3/Kawakami GDSC2 3.3657 5.1969 2.4207 5.5803
Karpas-1106P GDSC2 3.3761 6.2042 1.9257 8.6789
IM-9 GDSC2 3.4113 6.4881 1.8127 9.2882
BE-13 GDSC2 3.4314 6.6789 1.7338 9.7255
RPMI-8866 GDSC2 3.4361 9.906 0.1246 18.9661
SCC-3 GDSC2 3.4476 5.8682 2.1519 7.0491
MOLT-4 GDSC2 3.4581 7.6944 1.2481 12.6371
RS4;11 GDSC2 3.4657 8.9 0.6518 16.0794
H9 GDSC2 3.4674 10.1227 0.042 19.2868
MY-M12 GDSC2 3.4872 5.3952 2.4196 5.2507
EJM GDSC2 3.5124 9.7007 0.2899 17.8931
OCI-AML-3 GDSC2 3.5129 9.6069 0.3371 17.6446
MHH-CALL-2 GDSC2 3.5148 7.2741 1.5042 10.9154
VL51 GDSC2 3.5255 6.3834 1.9574 8.0601
KOPN-8 GDSC2 3.5317 5.8618 2.2224 6.3746
Raji GDSC2 3.5422 6.0366 2.1435 6.8435
DND-41 GDSC2 3.5615 7.7117 1.3234 11.889
CML-T1 GDSC2 3.5924 5.2304 2.5827 3.9505
EM-2 GDSC2 3.5966 7.6612 1.3767 11.4677
KMOE-2 GDSC2 3.6585 6.2767 2.1148 6.7169
BC-3 GDSC2 3.7254 6.6781 1.9671 7.4685
HDLM-2 GDSC2 3.7378 6.6134 2.0086 7.1769
DB GDSC2 3.7961 5.8138 2.4457 4.3117
JURL-MK1 GDSC2 3.7967 6.4643 2.1267 6.2921
KCL-22 GDSC2 3.8007 8.153 1.2929 11.4189
EoL-1 GDSC2 3.8096 5.7401 2.4913 3.9994
KMS-12-BM GDSC2 3.8127 10.2131 0.2763 17.1071
MOLT-13 GDSC2 3.8329 6.3751 2.1974 5.7635
L-428 GDSC2 3.8427 6.0545 2.3616 4.7231
HC-1 GDSC2 3.8453 5.7767 2.4987 3.8731
MN-60 GDSC2 3.8583 6.0858 2.3575 4.7119
LC4-1 GDSC2 3.9525 6.1917 2.3725 4.406
RC-K8 GDSC2 3.9688 8.2516 1.3733 10.4957
HL-60 GDSC2 3.9712 6.6459 2.165 5.6373
LAMA-84 GDSC2 3.9724 5.9525 2.5013 3.5811
SK-MM-2 GDSC2 4.0088 7.1628 1.9395 6.9383
NOMO-1 GDSC2 4.025 7.9008 1.5887 9.0497
OCI-AML-5 GDSC2 4.0283 9.1194 0.9888 12.6104
ROS-50 GDSC2 4.0608 8.3654 1.3864 10.1838
OCI-Ly19 GDSC2 4.0719 6.6893 2.2149 5.1043
OCI-AML-2 GDSC2 4.0807 9.3949 0.8923 13.0271
OCI-M1 GDSC2 4.0831 5.5217 2.773 1.7875
P31/FUJ GDSC2 4.1485 14.8114 -1.7493 24.7815
L-540 GDSC2 4.1573 6.1314 2.5373 2.9992
KM-H2 GDSC2 4.1901 8.9449 1.1971 10.9853
LP-1 GDSC2 4.2482 6.7654 2.2974 4.2352
K-562 GDSC2 4.2727 6.2971 2.5323 2.8176
CTV-1 GDSC2 4.3379 15.5727 -1.9787 25.0546
U266B1 GDSC2 4.3686 6.4959 2.4992 2.8377
SUP-B15 GDSC2 4.3945 6.4871 2.5187 2.6842
GDM-1 GDSC2 4.4861 14.6622 -1.4096 22.7152
Karpas-231 GDSC2 4.4915 5.8082 2.8655 0.7985
NKM-1 GDSC2 4.539 14.144 -1.1113 21.4511
JJN-3 GDSC2 4.5481 7.8627 1.9741 5.549
HEL GDSC2 4.5575 5.7882 2.9037 0.5874
KG-1 GDSC2 4.7925 6.6619 2.6598 1.3954
QIMR-WIL GDSC2 4.8254 11.4463 0.4344 13.6827
Granta-519 GDSC2 5.0485 7.5575 2.411 2.2826
SU-DHL-8 GDSC2 5.0579 6.1866 2.9572 0.1727
ME1 GDSC2 5.0903 6.4151 2.8882 0.3139
TK [Human B-cell lymphoma] GDSC2 5.098 6.9019 2.707 0.8963
MEG-01 GDSC2 5.298 7.1773 2.6877 0.812
YT GDSC2 5.3803 6.964 2.8019 0.4045
Karpas-299 GDSC2 5.7045 6.9817 2.9142 0.096
⏷ Show the Full List of 165 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACM5.1 C GDSC2 1.1155 7.11 -0.6224 30.6791
OACP4 C GDSC2 1.5799 5.5672 0.5481 23.1899
KYSE-220 GDSC2 2.4582 5.3174 1.5369 14.0798
ESO-26 GDSC2 2.9713 14.466 -2.5449 30.4236
FLO-1 GDSC2 3.0862 9.5856 -0.0085 20.6953
SK-GT-4 GDSC2 3.2322 10.9449 -0.5646 22.8169
KYSE-50 GDSC2 4.208 6.9337 2.1905 4.9585
ESO-51 GDSC2 4.6387 7.5996 2.1555 4.3169
HCE-4 GDSC2 4.9509 10.5502 0.9588 10.5681
KYAE-1 GDSC2 5.4758 12.1837 0.5321 11.7232
TE-12 GDSC2 5.7408 10.4189 1.5292 5.8857
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 0.82 7.5942 -1.14 33.8449
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB1 GDSC2 0.5046 6.1862 -0.8257 34.2106
SJNB-6 GDSC2 1.4 3.0206 1.2984 19.8137
NB69 GDSC2 2.2648 5.6674 1.1833 16.9145
SJNB-12 GDSC2 2.9021 5.7788 1.7282 11.3725
SK-N-MC-IXC GDSC2 3.001 6.7761 1.3206 13.5734
CHP-212 GDSC2 3.1978 11.6117 -0.9268 24.4295
Kelly GDSC2 3.4186 6.2917 1.9169 8.6129
SJNB-14 GDSC2 3.434 7.4652 1.3429 12.1322
SK-N-SH GDSC2 3.4728 10.6683 -0.2263 20.5669
LA-N-6 GDSC2 3.5352 6.7386 1.7879 9.0964
TGW GDSC2 3.6388 9.639 0.4234 16.8235
SK-N-DZ GDSC2 3.7329 5.665 2.4727 4.2931
IMR-5 GDSC2 3.7956 6.3141 2.1999 5.8385
NB(TU)1 GDSC2 3.8386 10.7156 0.0463 18.201
SK-N-BE(2)-M17 GDSC2 3.851 7.2128 1.7979 8.2
GI-ME-N GDSC2 3.9381 7.2154 1.8618 7.5879
KP-N-YS GDSC2 3.9386 6.5064 2.2098 5.4371
KP-N-YN GDSC2 3.9804 9.021 1.0008 12.6666
CHP-134 GDSC2 4.0535 6.4802 2.3031 4.6079
SJNB-13 GDSC2 4.1261 7.6309 1.7954 7.5445
SJNB-5 GDSC2 4.153 7.1184 2.0637 5.8453
SK-N-FI GDSC2 4.162 14.1184 -1.3932 23.4917
GOTO GDSC2 4.2643 7.0438 2.1757 4.9292
SiMa GDSC2 4.2661 7.6375 1.8914 6.6403
KP-N-RT-BM-1 GDSC2 4.6221 7.6987 2.0989 4.6747
CHP-126 GDSC2 4.655 7.3813 2.2662 3.6572
SJNB-10 GDSC2 4.7062 6.6703 2.612 1.729
SJNB-7 GDSC2 4.7959 7.1133 2.4679 2.3381
NH-12 GDSC2 4.9531 12.8926 -0.1815 16.4303
MHH-NB-11 GDSC2 5.0451 10.6867 0.9579 10.3675
SK-N-AS GDSC2 5.3159 14.9044 -0.9032 18.7434
SJNB-17 GDSC2 5.5806 8.2319 2.3961 1.7322
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 4.3326 8.3978 1.569 8.4333
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-148 GDSC2 -3.0855 1.5115 -3.2726 61.575
OCUB-M GDSC2 -2.8861 -0.8265 -2.8886 61.9302
Evsa-T GDSC2 -1.7843 2.8031 -2.118 50.8845
UACC-893 GDSC2 -0.9832 3.0484 -1.3046 43.923
HCC1569 GDSC2 -0.8237 4.6554 -1.6256 43.5103
MDA-MB-415 GDSC2 -0.5745 7.236 -2.3939 43.3411
MDA-MB-453 GDSC2 -0.3915 4.0856 -0.9623 39.2766
YMB-1-E GDSC2 -0.3859 5.9867 -1.67 41.1742
MDA-MB-361 GDSC2 0.1354 4.7927 -0.6445 35.2863
CAMA-1 GDSC2 0.214 5.5118 -0.8444 35.6028
HCC70 GDSC2 0.3518 7.3833 -1.5125 36.9883
MDA-MB-175-VII GDSC2 0.6124 5.9871 -0.6283 32.8659
MFM-223 GDSC2 0.6141 8.5394 -1.7837 36.5381
HCC2157 GDSC2 1.0416 6.0606 -0.2197 29.2951
MDA-MB-330 GDSC2 1.1761 6.7312 -0.3873 29.4459
BT-20 GDSC2 1.1844 9.3634 -1.6237 33.7525
Hs 578T GDSC2 1.2802 9.3114 -1.5075 33.0268
AU565 GDSC2 2.0674 9.0094 -0.6248 26.867
EFM-19 GDSC2 2.2161 9.4294 -0.6961 26.6317
COLO 824 GDSC2 2.4858 8.4162 0.0483 22.3212
HCC1954 GDSC2 2.5269 9.9153 -0.6587 25.4081
DU4475 GDSC2 2.9504 8.9211 0.207 19.9821
HCC1395 GDSC2 3.0297 15.2919 -2.9083 31.1344
MCF-7 GDSC2 3.1116 11.4895 -0.9385 24.6769
BT-474 GDSC2 3.1499 10.9383 -0.6306 23.2916
MRK-nu-1 GDSC2 3.4105 5.2622 2.4246 5.41
HCC1599 GDSC2 3.5333 6.7866 1.7624 9.229
HDQ-P1 GDSC2 3.56 11.2018 -0.4214 21.1517
HCC1419 GDSC2 3.5731 9.0579 0.6605 15.6709
EFM-192A GDSC2 3.6732 12.0394 -0.7476 22.2439
MDA-MB-468 GDSC2 3.9812 9.7096 0.6595 14.5491
HCC2218 GDSC2 3.9873 7.832 1.5945 9.0769
CAL-51 GDSC2 4.242 13.1692 -0.8576 21.1477
HCC1937 GDSC2 4.3269 13.5725 -0.9918 21.4706
HCC1428 GDSC2 4.4808 8.0442 1.8428 6.444
UACC-812 GDSC2 4.5189 8.4424 1.6776 7.3682
MDA-MB-157 GDSC2 4.5339 7.7108 2.0367 5.1902
CAL-85-1 GDSC2 4.6976 7.472 2.2504 3.6601
HCC1187 GDSC2 4.9666 7.2243 2.5109 1.8885
HCC1143 GDSC2 5.1215 9.4104 1.6149 6.4901
JIMT-1 GDSC2 5.1459 9.8579 1.4203 7.5421
BT-549 GDSC2 5.2013 13.6937 -0.3933 16.7771
HCC1500 GDSC2 5.4894 7.663 2.5824 1.0483
CAL-120 GDSC2 5.5398 14.2651 -0.4295 16.1743
MDA-MB-231 GDSC2 5.5695 13.077 0.1666 13.3261
HCC38 GDSC2 5.8739 12.6276 0.5853 10.608
HCC1806 GDSC2 5.906 13.7047 0.0942 12.9735
BT-483 GDSC2 6.0819 14.2755 -0.0606 13.3469
ZR-75-30 GDSC2 6.0864 17.1413 -1.4413 19.0968
MDA-MB-436 GDSC2 7.4459 15.8376 0.0755 10.2338
T-47D GDSC2 7.4711 22.4092 -3.024 21.5014
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-336MG GDSC2 1.9665 9.8437 -1.1276 29.2575
SW1088 GDSC2 2.1365 7.4013 0.2261 22.7349
SF539 GDSC2 2.1468 13.4413 -2.7476 33.4117
MOG-G-UVW GDSC2 2.6483 7.601 0.598 18.9464
PFSK-1 GDSC2 2.7589 12.365 -1.677 28.4945
Onda 10 GDSC2 2.8518 9.5665 -0.2003 22.3644
H4 GDSC2 2.9816 6.3578 1.5118 12.4612
GI-1 GDSC2 3.0244 7.786 0.8374 16.3679
D-247MG GDSC2 3.0328 14.5163 -2.518 30.1748
8-MG-BA GDSC2 3.1152 7.3231 1.1465 14.2692
SW1783 GDSC2 3.1743 6.3889 1.6637 10.9181
KALS-1 GDSC2 3.2854 18.2342 -4.1647 33.241
SF295 GDSC2 3.3056 12.3431 -1.2022 25.1716
MOG-G-CCM GDSC2 3.3209 6.9433 1.5104 11.4335
D283 Med GDSC2 3.3817 10.5123 -0.2236 20.8246
YH-13 GDSC2 3.4074 9.4132 0.3473 17.9015
LNZTA3WT4 GDSC2 3.4316 11.3095 -0.5809 22.2897
LN-18 GDSC2 3.4559 8.5555 0.8159 15.1834
CAS-1 GDSC2 3.5324 11.645 -0.6655 22.3584
YKG-1 GDSC2 3.7131 5.8048 2.3895 4.8592
M059J GDSC2 3.7284 9.8147 0.4078 16.6527
42-MG-BA GDSC2 3.8056 16.3009 -2.769 28.7488
AM-38 GDSC2 3.9217 7.0269 1.9424 7.1295
D-542MG GDSC2 3.944 10 0.4861 15.6384
KS-1 [Human Krukenberg tumour] GDSC2 3.9948 15.1005 -2.0165 26.0604
Becker GDSC2 4.0631 8.8129 1.167 11.4823
SK-MG-1 GDSC2 4.0711 12.7266 -0.7716 21.2981
D-502MG GDSC2 4.2488 6.6365 2.3587 3.8709
LN-405 GDSC2 4.3659 11.8668 -0.1147 17.5708
U-118MG GDSC2 4.4521 9.4387 1.1466 10.6436
ONS-76 GDSC2 4.4911 13.3763 -0.7673 20.178
Hs 683 GDSC2 4.5132 8.3766 1.7053 7.2157
A-172 GDSC2 4.5577 13.1763 -0.6171 19.3685
DK-MG GDSC2 4.5636 15.1824 -1.6079 23.2339
Onda 11 GDSC2 4.5737 8.7611 1.5617 7.9355
D-245MG GDSC2 4.5823 10.6496 0.648 13.1275
T98G GDSC2 4.6042 9.8998 1.0307 10.9501
D-263MG GDSC2 4.6184 7.7557 2.0699 4.8497
KNS-81-FD GDSC2 4.7036 10.2771 0.9177 11.3553
D-566MG GDSC2 4.8155 7.3651 2.3676 2.838
GaMG GDSC2 4.8246 18.219 -2.9143 26.6485
SF126 GDSC2 4.829 11.4103 0.4546 13.5687
SNB-75 GDSC2 4.9278 12.8768 -0.1922 16.5409
NMC-G1 GDSC2 4.9986 6.6473 2.7627 0.7658
U-251MG GDSC2 5.0388 11.6142 0.5049 12.8207
KNS-42 GDSC2 5.0408 6.8754 2.6915 1.0065
GB-1 GDSC2 5.052 10.8861 0.8665 10.8548
D-423MG GDSC2 5.0684 12.055 0.3114 13.7507
Daoy GDSC2 5.6081 13.381 0.0467 13.8624
KINGS-1 GDSC2 5.6378 18.3555 -2.3629 23.2219
D-392MG GDSC2 5.7759 14.8444 -0.5445 16.2048
LN-229 GDSC2 5.9816 12.6108 0.6628 10.0338
U-87MG ATCC GDSC2 6.4868 16.5738 -0.888 16.1717
SF268 GDSC2 7.162 19.1019 -1.6427 17.7285
DBTRG-05MG GDSC2 7.2729 16.9077 -0.5282 13.1949
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC2 3.1186 10.4381 -0.407 22.4692
TGBC24TKB GDSC2 3.9447 8.8125 1.0768 12.3182
ETK-1 GDSC2 3.9777 6.6289 2.178 5.5423
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 GDSC2 0.1149 6.8208 -1.5034 38.1915
AN3-CA GDSC2 0.6284 11.3895 -3.1295 39.38
MFE-280 GDSC2 1.9352 10.1997 -1.3314 30.0852
EN GDSC2 2.2602 14.0946 -2.9729 33.5849
MFE-296 GDSC2 2.641 7.9252 0.4308 19.8831
MFE-319 GDSC2 2.6804 8.2156 0.3218 20.3295
ESS-1 GDSC2 3.7202 9.7365 0.4402 16.5032
KLE GDSC2 5.0508 15.0087 -1.1506 20.3506
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-54 GDSC2 0.9665 11.2551 -2.7455 37.4147
SW156 GDSC2 1.0845 8.2108 -1.1689 32.8114
A-498 GDSC2 1.2389 9.1496 -1.4688 33.1502
786-O GDSC2 1.6693 11.0219 -1.9793 33.0328
KTCTL-26A GDSC2 2.0562 8.0355 -0.158 24.917
KTCTL-140 GDSC2 2.1907 9.9505 -0.9766 27.9015
BFTC-909 GDSC2 2.3019 15.7972 -3.7849 35.139
KMRC-1 GDSC2 2.7355 10.8852 -0.9589 26.0016
LB996-RCC GDSC2 2.8572 11.6445 -1.2327 26.65
RXF 393L GDSC2 3.248 12.9994 -1.5786 26.6888
NCC021 GDSC2 3.4098 7.494 1.3086 12.4106
A-704 GDSC2 3.6316 9.5843 0.445 16.7289
UO-31 GDSC2 3.7453 6.0976 2.2692 5.5303
LB2241-RCC GDSC2 3.9031 6.9265 1.9781 6.9544
OS-RC-2 GDSC2 3.9661 10.3909 0.3089 16.5151
BB65-RCC GDSC2 3.9683 8.0153 1.4898 9.7932
SW13 GDSC2 4.1116 10.1305 0.5513 14.8397
VMRC-RCW GDSC2 4.2219 7.9918 1.6879 7.974
TK-10 GDSC2 4.2306 9.5296 0.939 12.3775
KMRC-20 GDSC2 4.3603 7.5133 2.0157 5.6871
KTCTL-13 GDSC2 4.3789 10.0118 0.8118 12.7249
KTCTL-21 GDSC2 4.7214 10.9344 0.6096 13.0016
HA7-RCC GDSC2 4.8526 11.7662 0.2976 14.3235
LB1047-RCC GDSC2 4.9965 8.3324 2.0365 4.3591
KTCTL-1M GDSC2 5.1185 7.7542 2.3633 2.4288
RCC10RGB GDSC2 5.2149 11.7704 0.5523 12.1794
ACHN GDSC2 5.2713 15.6223 -1.2889 20.3656
NCC010 GDSC2 5.3195 16.6292 -1.7492 21.9236
KTCTL-195 GDSC2 5.327 16.0816 -1.4738 20.9259
VMRC-RCZ GDSC2 5.6399 15.6409 -1.0289 18.5199
SN12C GDSC2 5.8463 7.365 2.8339 0.1776
769-P GDSC2 6.338 16.0783 -0.7514 15.9097
Caki-1 GDSC2 6.617 14.76 0.0604 11.7806
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H508 GDSC2 -1.4946 7.8294 -3.6012 49.1209
LS411N GDSC2 0.2568 6.8805 -1.3843 37.1788
LoVo GDSC2 0.784 10.016 -2.3197 37.2081
DiFi GDSC2 0.8352 6.385 -0.5743 31.7212
NCI-H747 GDSC2 0.9555 9.8087 -2.0562 35.9083
SW948 GDSC2 1.1233 11.1277 -2.5366 36.3956
SNU-C1 GDSC2 1.3961 7.1383 -0.3588 28.3995
HCC2998 GDSC2 1.4127 8.6853 -1.0797 31.1732
GP5d GDSC2 1.6506 9.6412 -1.3196 31.0852
HT-29 GDSC2 1.9002 9.231 -0.8874 28.6032
HCT 15 GDSC2 1.9948 8.7514 -0.5651 26.9558
LS513 GDSC2 2.0012 7.5893 0.0077 24.3292
SNU-175 GDSC2 2.151 8.8629 -0.476 26.0063
SNU-C5 GDSC2 2.5658 13.1636 -2.2424 30.8034
SNU-407 GDSC2 2.5868 14.2771 -2.7797 32.1483
NCI-H716 GDSC2 2.765 7.5474 0.7288 17.8244
COLO205 GDSC2 2.8321 6.9105 1.1047 15.418
SNU-1040 GDSC2 3.2908 19.683 -4.8845 34.5056
SNU-283 GDSC2 3.3567 10.9778 -0.4771 22.0567
HT-55 GDSC2 3.3723 10.9838 -0.4671 21.966
MDST8 GDSC2 3.6447 11.9141 -0.7082 22.2155
C2BBe1 GDSC2 3.7708 8.7784 0.9582 13.4751
CL-11 GDSC2 3.7832 11.8816 -0.5798 21.272
SW48 GDSC2 3.9319 14.5063 -1.7704 25.4242
CaR-1 GDSC2 3.9522 8.3875 1.2933 11.0182
T84 GDSC2 3.9579 9.0482 0.97 12.9034
RKO GDSC2 4.1389 13.9773 -1.3412 23.361
HCT 116 GDSC2 4.154 8.9715 1.157 11.3105
KM12 GDSC2 4.1817 15.163 -1.8982 25.1914
LS180 GDSC2 4.1894 11.4156 -0.0267 17.6072
HT115 GDSC2 4.192 7.4459 1.9324 6.5576
SNU-81 GDSC2 4.2192 11.699 -0.1443 18.0955
CCK-81 GDSC2 4.2471 9.6589 0.8876 12.6279
CW-2 GDSC2 4.3862 12.779 -0.5516 19.5217
SK-CO-1 GDSC2 4.4791 6.5053 2.5598 2.3212
COLO 320HSR GDSC2 4.4977 6.7528 2.459 2.8441
SNU-61 GDSC2 4.6888 9.1892 1.4345 8.4311
RCM-1 [Human ESC] GDSC2 4.69 9.7467 1.1659 9.982
SNU-C2B GDSC2 4.8954 10.6714 0.8616 11.229
SW1116 GDSC2 4.8998 6.7957 2.6572 1.29
SW1463 GDSC2 5.1285 8.3753 2.0947 3.8224
SW837 GDSC2 5.2718 7.3304 2.6158 1.1056
LS1034 GDSC2 5.4176 6.8622 2.8528 0.2668
COLO 678 GDSC2 5.5033 12.6316 0.3357 12.666
SW620 GDSC2 5.8302 7.855 2.6534 0.5888
SW1417 GDSC2 6.2822 20.2468 -2.8181 23.226
SW626 GDSC2 6.3537 15.0491 -0.2482 13.6993
LS123 GDSC2 7.1357 21.2286 -2.6866 21.1783
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 3.5104 5.643 2.3145 5.8508
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep 3B2.1-7 GDSC2 1.3585 6.4549 -0.0782 27.2829
JHH-2 GDSC2 1.8258 12.1858 -2.4112 33.6327
SNU-387 GDSC2 4.0015 11.7706 -0.3502 19.6418
Hep-G2/C3A GDSC2 4.2628 8.058 1.6848 7.8975
SNU-423 GDSC2 4.3266 11.7906 -0.107 17.6355
SNU-398 GDSC2 4.342 8.0706 1.7346 7.4173
HuH-1 GDSC2 4.3793 10.6432 0.5008 14.4207
SNU-449 GDSC2 4.8026 13.8328 -0.7563 19.3528
Huh-7 GDSC2 4.9706 12.1114 0.2139 14.4693
JHH-1 GDSC2 5.0502 6.4676 2.853 0.4296
JHH-6 GDSC2 5.1659 12.9002 -0.031 15.2181
SK-HEP-1 GDSC2 5.3056 16.3837 -1.6385 21.5678
HLE GDSC2 5.4026 7.9925 2.4081 1.8683
JHH-7 GDSC2 5.6543 14.4471 -0.4371 15.9972
JHH-4 GDSC2 7.025 18.8394 -1.6098 17.8704
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 184 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H720 GDSC2 -0.9796 4.3075 -1.6743 44.7107
DMS 273 GDSC2 -0.4591 5.6599 -1.6151 41.461
NCI-H847 GDSC2 0.1877 8.075 -1.9919 39.0164
IST-SL2 GDSC2 0.2656 3.3181 -0.0125 32.039
COR-L279 GDSC2 0.3507 4.2186 -0.2032 32.4841
KNS-62 GDSC2 0.4407 6.9027 -1.2066 35.7799
RERF-LC-Sq1 GDSC2 0.5213 5.378 -0.4663 32.7576
Lu-134-A GDSC2 0.5453 5.0366 -0.3027 31.9566
EPLC-272H GDSC2 0.5881 8.1116 -1.6099 36.2778
NCI-H446 GDSC2 1.0386 7.2369 -0.7576 31.5363
NCI-H460 GDSC2 1.107 12.2687 -3.1091 37.6187
COR-L32 GDSC2 1.1996 3.7174 0.8868 22.962
NCI-H1993 GDSC2 1.2609 8.1615 -0.9745 31.4071
NCI-H2171 GDSC2 1.3417 3.8777 0.9871 21.776
NCI-H835 GDSC2 1.565 5.1813 0.7036 22.4002
NCI-H1781 GDSC2 1.6882 12.3613 -2.6223 34.6056
NCI-H64 GDSC2 1.744 5.0006 0.9665 20.1901
SBC-1 GDSC2 1.9465 5.1842 1.0915 18.6631
NCI-H2122 GDSC2 1.961 6.1524 0.658 21.0809
NCI-H69 GDSC2 2.0172 9.1034 -0.717 27.5018
Lu-65 GDSC2 2.0218 6.7453 0.4346 22.0682
NCI-H1648 GDSC2 2.0267 5.5386 1.0098 18.8279
NCI-H1944 GDSC2 2.056 8.8597 -0.5617 26.7176
NCI-H1703 GDSC2 2.0814 8.5182 -0.3708 25.7966
NCI-H1975 GDSC2 2.1931 8.8617 -0.4371 25.6854
HARA [Human squamous cell lung carcinoma] GDSC2 2.2026 7.2887 0.3428 21.887
NCI-H2110 GDSC2 2.2174 10.7952 -1.3709 29.2346
NCI-H82 GDSC2 2.2258 4.9323 1.4872 15.2438
NCI-H1623 GDSC2 2.3421 9.8738 -0.8025 26.695
COR-L311 GDSC2 2.3573 4.928 1.6206 13.9438
NCI-H2009 GDSC2 2.5955 10.7099 -0.9936 26.5929
NCI-H2066 GDSC2 2.6092 8.5446 0.0952 21.7329
NCI-H1155 GDSC2 2.6596 7.4869 0.6646 18.5378
Ms-1 GDSC2 2.6909 4.4543 2.1711 9.3554
NCI-H520 GDSC2 2.7104 10.4493 -0.7634 25.3008
NCI-H1770 GDSC2 2.7211 4.681 2.0941 9.7171
DMS 79 GDSC2 2.7356 5.987 1.474 13.4981
LC-1/sq GDSC2 2.7449 8.9956 -0.009 21.7955
COR-L303 GDSC2 2.9296 6.6592 1.3161 13.828
HCC44 GDSC2 2.9607 8.9871 0.1829 20.1327
COR-L105 GDSC2 2.9619 8.2332 0.5601 18.1265
Lu-135 GDSC2 2.9717 5.136 2.1087 8.7641
NCI-H2373 GDSC2 2.9776 14.0972 -2.3552 29.8866
NCI-H1437 GDSC2 3.0045 5.7292 1.8445 10.3147
LXF 289 GDSC2 3.0097 6.9859 1.2236 14.1347
A-549 GDSC2 3.0729 10.2266 -0.3401 22.3081
CPC-N GDSC2 3.115 6.8135 1.4008 12.7273
COLO 668 GDSC2 3.1764 6.9066 1.4069 12.5024
SBC-3 GDSC2 3.2029 8.5368 0.6146 17.0722
NCI-H2170 GDSC2 3.2677 6.9089 1.4831 11.7594
NCI-H292 GDSC2 3.3082 6.7574 1.5927 10.9607
LB647-SCLC GDSC2 3.3098 7.652 1.1468 13.6784
PC-14 GDSC2 3.3329 9.3929 0.2956 18.3955
NCI-H2023 GDSC2 3.3383 13.4024 -1.7047 26.8516
NCI-H2196 GDSC2 3.3694 6.3294 1.8575 9.1266
Lu-139 GDSC2 3.4018 4.7154 2.6905 3.7715
NCI-H2731 GDSC2 3.4158 10.5633 -0.2208 20.7098
NCI-H250 GDSC2 3.4269 8.0054 1.0671 13.808
NCI-H2228 GDSC2 3.4293 9.4916 0.3261 17.9483
NCI-H2804 GDSC2 3.4415 10.2251 -0.0306 19.7214
NCI-H3122 GDSC2 3.4468 12.837 -1.332 25.239
NCI-H838 GDSC2 3.5521 7.7761 1.2837 12.1555
BEN GDSC2 3.5583 5.7559 2.2959 5.8406
NCI-H1048 GDSC2 3.5713 10.6854 -0.1542 19.9375
NCI-H1755 GDSC2 3.5782 10.0871 0.1505 18.4188
SBC-5 GDSC2 3.5816 6.5901 1.8989 8.2752
NCI-H1838 GDSC2 3.5844 14.3715 -1.9857 27.0679
NCI-H345 GDSC2 3.6075 6.6251 1.9019 8.1865
RERF-LC-MS GDSC2 3.6295 6.9494 1.7577 9.0281
NCI-H1693 GDSC2 3.6649 9.2857 0.6208 15.678
COR-L95 GDSC2 3.6814 8.2273 1.162 12.525
NCI-H2030 GDSC2 3.6887 8.2186 1.1721 12.4444
Calu-3 GDSC2 3.7291 10.161 0.2355 17.5518
NCI-H1688 GDSC2 3.7377 8.7133 0.9644 13.5301
EMC-BAC-1 GDSC2 3.7486 10.7308 -0.0332 18.8453
LCLC-97TM1 GDSC2 3.7933 10.6145 0.0606 18.2566
NCI-H211 GDSC2 3.801 7.0288 1.851 7.9979
Lu-165 GDSC2 3.8166 8.0771 1.3429 11.0756
NCI-H2141 GDSC2 3.828 6.7675 2.0006 6.9999
LC-2/ad GDSC2 3.8578 6.0706 2.3645 4.6698
NCI-H1666 GDSC2 3.8584 12.0883 -0.6226 21.2469
NCI-H1436 GDSC2 3.8951 7.4855 1.6964 8.7156
NCI-H596 GDSC2 3.9947 12.7963 -0.867 21.9002
NCI-H647 GDSC2 4.0151 6.908 2.0686 6.1285
NCI-H209 GDSC2 4.0305 7.7093 1.6871 8.4356
HOP-92 GDSC2 4.0469 8.9934 1.0654 12.1184
NCI-H2081 GDSC2 4.0492 14.1215 -1.4844 24.1207
NCI-H1435 GDSC2 4.077 9.6787 0.7488 13.8453
NCI-H1694 GDSC2 4.1268 6.939 2.1323 5.4862
NCI-H1734 GDSC2 4.1563 8.0311 1.6213 8.5318
NCI-H2722 GDSC2 4.1629 7.1201 2.0698 5.7865
NCI-H2291 GDSC2 4.1693 10.4595 0.4324 15.3244
CAL-12T GDSC2 4.1866 13.2273 -0.9299 21.6411
NCI-H526 GDSC2 4.1937 6.5924 2.3437 4.0698
NCI-H1876 GDSC2 4.2052 9.0062 1.1781 11.059
NCI-H2029 GDSC2 4.2218 7.5443 1.9055 6.6536
DMS 53 GDSC2 4.2386 8.757 1.3254 10.1092
HCC78 GDSC2 4.2461 9.9499 0.7431 13.4406
NCI-H1341 GDSC2 4.2647 9.4787 0.9895 12.0037
NCI-H524 GDSC2 4.3267 7.8252 1.8427 6.8001
IST-SL1 GDSC2 4.3367 7.1002 2.1969 4.6547
NCI-H522 GDSC2 4.3605 11.4945 0.0656 16.7069
RERF-LC-KJ GDSC2 4.3668 13.5537 -0.9514 21.2558
HOP-62 GDSC2 4.3778 8.4948 1.5539 8.4196
NCI-H2810 GDSC2 4.3939 7.0837 2.2418 4.2768
SHP-77 GDSC2 4.4003 9.8146 0.9246 12.0387
NCI-H1869 GDSC2 4.4162 9.1871 1.2438 10.1639
NCI-H810 GDSC2 4.4441 6.4848 2.5489 2.4358
NCI-H2444 GDSC2 4.4723 5.8078 2.8565 0.8561
NCI-H2085 GDSC2 4.4744 8.4389 1.6486 7.638
A-427 GDSC2 4.4955 13.2087 -0.6807 19.8002
SW1271 GDSC2 4.5097 7.6616 2.0442 5.2124
EMC-BAC-2 GDSC2 4.5448 12.6872 -0.3847 18.3711
Calu-6 GDSC2 4.5476 7.4047 2.1892 4.2908
NCI-H358 GDSC2 4.5954 11.1091 0.4319 14.2478
NCI-H146 GDSC2 4.6021 10.7221 0.6269 13.194
NCI-H513 GDSC2 4.6118 7.9486 1.975 5.4169
NCI-H2347 GDSC2 4.6198 7.5469 2.1682 4.2785
NCI-H2227 GDSC2 4.6804 7.6437 2.161 4.2098
NCI-H226 GDSC2 4.7298 6.2357 2.8043 0.8294
NCI-H2869 GDSC2 4.7718 8.1106 2.0011 4.9597
NCI-H2369 GDSC2 4.7872 6.9138 2.5501 1.9315
NCI-H1092 GDSC2 4.803 12.5067 -0.1022 16.4162
COR-L23 GDSC2 4.88 14.358 -0.9575 19.9943
COR-L321 GDSC2 4.9006 7.1046 2.5278 1.8958
NCI-H3255 GDSC2 4.9651 12.429 0.0546 15.2712
NCI-H2087 GDSC2 5.019 7.7538 2.3094 2.8434
HCC33 GDSC2 5.019 12.3472 0.1336 14.7565
COR-L88 GDSC2 5.0219 6.5832 2.7976 0.6238
NCI-H1651 GDSC2 5.0451 7.5756 2.4014 2.3351
NCI-H1581 GDSC2 5.0463 8.3487 2.0587 4.1525
NCI-H1650 GDSC2 5.0499 8.4569 2.0116 4.4073
IA-LM GDSC2 5.0731 6.7939 2.7383 0.7981
NCI-H1792 GDSC2 5.1101 8.6775 1.9469 4.6645
SK-MES-1 GDSC2 5.1317 12.1792 0.2959 13.685
HCC827 GDSC2 5.1378 11.7305 0.518 12.5296
NCI-H1836 GDSC2 5.1503 7.2648 2.5855 1.3461
LK-2 GDSC2 5.1776 6.9694 2.7159 0.8002
NCI-H1963 GDSC2 5.1779 7.0732 2.6753 0.9522
NCI-H1355 GDSC2 5.1916 12.7175 0.0764 14.6397
DMS 114 GDSC2 5.1945 10.082 1.346 7.8899
HCC15 GDSC2 5.2153 9.2027 1.7696 5.4697
UMC-11 GDSC2 5.217 7.1276 2.6714 0.9351
Lu-99A GDSC2 5.2608 13.7581 -0.3818 16.6312
NCI-H650 GDSC2 5.2901 7.7334 2.4603 1.755
NCI-H2795 GDSC2 5.3022 15.2838 -1.0996 19.5627
NCI-H841 GDSC2 5.3029 7.2588 2.6581 0.9163
NCI-H23 GDSC2 5.3251 7.4081 2.6092 1.0854
LOU-NH91 GDSC2 5.3419 21.4887 -4.1378 28.4912
NCI-H1105 GDSC2 5.3621 17.2765 -2.0367 22.7956
NCI-H727 GDSC2 5.4302 14.8912 -0.8136 18.1136
NCI-H290 GDSC2 5.4318 7.871 2.4724 1.5519
NCI-H1563 GDSC2 5.4724 17.208 -1.9206 22.1626
NCI-H2342 GDSC2 5.5013 16.366 -1.485 20.5715
NCI-H2461 GDSC2 5.5041 14.9972 -0.8121 17.9405
HCC366 GDSC2 5.5067 12.5547 0.375 12.4605
VMRC-LCD GDSC2 5.5107 7.4649 2.6683 0.731
NCI-H740 GDSC2 5.6096 8.069 2.4758 1.368
NCI-H2818 GDSC2 5.6202 8.0869 2.4736 1.3676
NCI-H1573 GDSC2 5.6393 7.2496 2.7986 0.305
NCI-H510A GDSC2 5.6566 7.2167 2.8166 0.2611
ABC-1 GDSC2 5.6646 15.1527 -0.773 17.4207
NCI-H2803 GDSC2 5.6708 8.334 2.3975 1.6359
SK-LU-1 GDSC2 5.6985 11.1251 1.1783 7.8519
NCI-H661 GDSC2 5.7281 7.8356 2.6188 0.7531
EBC-1 GDSC2 5.7445 16.6628 -1.4531 19.9153
NCI-H748 GDSC2 5.7606 7.8799 2.6156 0.743
ChaGo-K-1 GDSC2 5.7639 12.6122 0.5203 11.1895
NCI-H1568 GDSC2 5.8107 12.6871 0.5157 11.1192
NCI-H2172 GDSC2 5.8602 7.4175 2.8208 0.1954
NCI-H2591 GDSC2 5.8922 13.3213 0.268 12.1932
NCI-H2135 GDSC2 5.9134 7.6719 2.7516 0.3091
NCI-H1299 GDSC2 5.9511 19.4009 -2.6455 23.4054
NCI-H322M GDSC2 5.9715 16.6653 -1.2913 18.8202
NCI-H2595 GDSC2 5.9722 14.1631 -0.0807 13.7001
NCI-H2405 GDSC2 5.9967 13.2733 0.3599 11.5311
EKVX GDSC2 6.2163 9.768 2.072 2.4974
SW1573 GDSC2 6.2518 13.6974 0.3255 11.2047
NCI-H1915 GDSC2 6.5054 14.9807 -0.1158 12.8037
LCLC-103H GDSC2 6.5539 16.6177 -0.8635 15.939
NCI-H1793 GDSC2 6.6309 16.7238 -0.8623 15.782
PaCa-3 GDSC2 6.6433 8.6884 2.6637 0.2598
NCI-H441 GDSC2 6.8735 19.7248 -2.1414 19.9786
NCI-H196 GDSC2 7.4959 17.995 -0.896 14.3042
⏷ Show the Full List of 184 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 3.9341 8.9146 1.0179 12.6893
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-140 GDSC2 -0.2461 5.7871 -1.4412 39.8902
OE21 GDSC2 1.1961 6.3936 -0.2129 28.592
TE-6 GDSC2 1.4523 8.6294 -1.015 30.786
EC-GI-10 GDSC2 1.9523 8.9262 -0.6899 27.6294
KYSE-180 GDSC2 2.9251 8.5396 0.3755 19.2426
TE-11 GDSC2 3.3319 6.7319 1.6252 10.6889
KYSE-520 GDSC2 3.3732 9.6122 0.2194 18.6701
KYSE-270 GDSC2 3.3892 10.3049 -0.1136 20.2798
KYSE-150 GDSC2 3.5125 7.6274 1.3259 12.0118
T.T GDSC2 3.5251 5.1178 2.5872 4.094
TE-4 GDSC2 3.7293 9.596 0.5176 16.0611
TE-9 GDSC2 4.0997 6.9762 2.0954 5.7717
OE33 GDSC2 4.2134 11.343 0.0279 17.2764
TE-10 GDSC2 4.3064 6.2659 2.567 2.5629
TE-1 GDSC2 4.4178 6.7439 2.4151 3.2285
TE-8 GDSC2 4.5358 14.4794 -1.2802 22.1081
KYSE-410 GDSC2 4.5531 8.2403 1.7977 6.5821
TE-5 GDSC2 4.6517 14.4525 -1.1777 21.4264
TE-15 GDSC2 5.0669 17.3899 -2.316 24.3577
KYSE-70 GDSC2 5.2033 10.1448 1.3221 8.0068
COLO 680N GDSC2 5.2579 11.9518 0.4945 12.3861
KYSE-450 GDSC2 5.3611 10.8244 1.1036 8.9061
KYSE-510 GDSC2 5.5569 11.1826 1.0616 8.7502
OE19 GDSC2 5.6592 13.435 0.0558 13.7092
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IGROV-1 GDSC2 -2.023 3.6756 -2.6115 52.7061
TOV-21G GDSC2 -0.3374 6.23 -1.7195 41.018
EFO-27 GDSC2 0.22 10.6745 -3.1771 41.0228
A2780 GDSC2 0.9837 4.4334 0.3992 26.5464
JHOS-4 GDSC2 1.9672 7.9218 -0.1857 25.3773
DOV13 GDSC2 3.9026 10.419 0.2449 17.0201
ES-2 GDSC2 3.9094 9.0599 0.9266 13.2821
OVK18 GDSC2 4.1499 11.5783 -0.1382 18.2504
TYK-nu GDSC2 4.2242 8.903 1.243 10.6312
Caov-4 GDSC2 4.3605 7.0113 2.2543 4.2679
OVISE GDSC2 4.3671 13.4887 -0.9188 21.1233
OVCAR-5 GDSC2 4.4928 11.5202 0.153 15.9342
FU-OV-1 GDSC2 4.6357 6.7449 2.5416 2.1839
JHOS-2 GDSC2 4.7666 7.442 2.305 3.2543
OC 314 GDSC2 4.9683 14.2404 -0.8333 19.2725
OV-90 GDSC2 5.0632 10.1323 1.2358 8.7767
OV56 GDSC2 5.1154 6.2224 2.9656 0.1418
Caov-3 GDSC2 5.1164 8.442 2.0576 4.0433
OAW42 GDSC2 5.1263 14.2652 -0.7285 18.458
TOV-112D GDSC2 5.1838 7.6394 2.4463 1.9414
EFO-21 GDSC2 5.1891 7.463 2.5227 1.5826
OVTOKO GDSC2 5.2032 13.5007 -0.2975 16.3814
OVKATE GDSC2 5.263 7.0478 2.7225 0.715
OVCAR-3 GDSC2 5.3962 13.8936 -0.3508 16.1838
OAW28 GDSC2 5.5886 9.0828 2.0391 3.431
SK-OV-3 GDSC2 5.768 19.1819 -2.6733 23.8736
OVCAR-4 GDSC2 5.816 7.6843 2.7102 0.4426
RMG-I GDSC2 5.9102 9.0435 2.2219 2.1567
OVCAR-8 GDSC2 6.3666 13.2379 0.6133 9.57
Kuramochi GDSC2 7.0163 16.3023 -0.4082 13.1465
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DAN-G GDSC2 3.5002 9.3326 0.4638 17.0074
BxPC-3 GDSC2 3.5349 12.2198 -0.9508 23.5286
Panc 04.03 GDSC2 3.7607 5.3096 2.6658 3.039
Panc 03.27 GDSC2 4.0331 5.5539 2.7282 2.1253
KP-4 GDSC2 4.0519 6.0523 2.5066 3.3856
HuP-T3 GDSC2 4.0865 6.3957 2.3661 4.1564
CFPAC-1 GDSC2 4.3027 8.4314 1.5313 8.7285
PSN1 GDSC2 4.431 6.4178 2.5714 2.3339
KP-1N GDSC2 4.4635 8.0481 1.8292 6.5841
HPAC GDSC2 4.6219 7.8178 2.0431 4.9995
QGP-1 GDSC2 4.6845 11.3026 0.4023 14.186
YAPC GDSC2 4.7334 6.6785 2.6227 1.6422
AsPC-1 GDSC2 4.8618 11.9539 0.2123 14.7335
Panc 08.13 GDSC2 4.9074 14.0529 -0.7864 19.2239
MIA PaCa-2 GDSC2 4.93 11.2217 0.6187 12.467
Hs 766T GDSC2 4.9668 10.5713 0.9596 10.5285
Capan-1 GDSC2 4.9747 6.7066 2.7286 0.9164
Panc 10.05 GDSC2 4.9811 13.537 -0.4774 17.7142
PL4 GDSC2 5.2213 7.0325 2.7104 0.7871
PaTu 8988t GDSC2 5.2324 12.1684 0.372 13.0727
SU.86.86 GDSC2 5.2419 6.5495 2.8977 0.2325
PaTu 8902 GDSC2 5.3224 12.5834 0.2338 13.5695
HPAF-II GDSC2 5.6785 16.7307 -1.5343 20.3566
Panc 02.03 GDSC2 5.6942 7.4269 2.7561 0.3814
KP-2 GDSC2 5.8426 12.7631 0.5006 11.1322
MZ-PC-1 GDSC2 5.9218 7.778 2.7171 0.3818
SUIT-2 GDSC2 6.0389 7.3504 2.9051 0.0628
HuP-T4 GDSC2 6.1057 7.8196 2.7703 0.2176
SW1990 GDSC2 6.1214 7.942 2.7336 0.2788
Capan-2 GDSC2 6.2058 16.084 -0.845 16.5663
KP-3 GDSC2 6.2919 15.9586 -0.7253 15.8947
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC2 3.9388 8.7961 1.0804 12.3127
MSTO-211H GDSC2 4.1204 8.3829 1.4222 9.8209
NCI-H2452 GDSC2 4.1546 10.5655 0.3685 15.6999
NCI-H28 GDSC2 4.8414 9.9422 1.1766 9.5846
NCI-H2052 GDSC2 5.9694 14.3667 -0.1802 14.1668
IST-Mes1 GDSC2 6.2426 19.3035 -2.3848 22.0118
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC2 -4.6183 -0.194 -4.6949 73.7691
22Rv1 GDSC2 1.7171 8.5874 -0.7441 28.7304
VCaP GDSC2 1.8802 8.6549 -0.6243 27.6277
NCI-H660 GDSC2 4.0279 6.379 2.3342 4.4741
DU145 GDSC2 4.4632 9.6877 1.0328 11.2709
PC-3 GDSC2 7.1042 20.1359 -2.1798 19.6621
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 2.8763 8.1775 0.5135 18.6571
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-144 GDSC2 0.684 4.3478 0.1097 29.3948
SK-MEL-3 GDSC2 1.2832 4.5325 0.6798 23.7235
SK-MEL-31 GDSC2 1.3115 7.8206 -0.7634 30.411
SK-MEL-24 GDSC2 1.563 6.0501 0.312 24.5093
A-388 GDSC2 1.6624 7.7829 -0.4073 27.5419
Hs 938.T GDSC2 1.8985 6.0137 0.6618 21.3002
MZ-MEL-7 GDSC2 2.141 4.2098 1.7159 14.2214
WM115 GDSC2 2.1425 6.7684 0.5386 21.0571
Mel Ho GDSC2 2.1487 4.7619 1.486 15.5489
A-431 GDSC2 2.2144 9.4261 -0.696 26.7084
IST-MEL1 GDSC2 2.3101 6.6881 0.7358 19.3519
A101D GDSC2 2.4052 6.1655 1.0789 17.0262
RPMI-7951 GDSC2 2.4723 9.8851 -0.6921 25.7999
CP50-MEL-B GDSC2 2.5422 5.8676 1.3525 14.903
LOX-IMVI GDSC2 2.5636 11.8171 -1.5731 28.7701
COLO 792 GDSC2 2.6296 6.6837 1.0342 16.5106
HMV-II GDSC2 2.873 5.6887 1.7463 11.3551
IGR-1 GDSC2 2.9158 4.9093 2.1687 8.5749
IGR-37 GDSC2 2.9506 6.2123 1.5567 12.2822
G-361 GDSC2 3.0128 9.4545 -0.0057 20.9124
SK-MEL-1 GDSC2 3.0414 3.8682 2.7903 4.2811
WM1552C GDSC2 3.0624 8.0496 0.7385 16.8131
A2058 GDSC2 3.1707 6.9855 1.3627 12.7907
GAK GDSC2 3.2305 4.6011 2.6046 4.8149
SK-MEL-28 GDSC2 3.2967 9.508 0.2079 18.9592
SK-MEL-30 GDSC2 3.3127 8.8051 0.5727 16.9704
SH-4 GDSC2 3.3234 6.7806 1.5938 10.9091
G-mel GDSC2 3.3236 5.0549 2.4568 5.4726
WM35 GDSC2 3.3806 8.9088 0.5772 16.7426
COLO 679 GDSC2 3.3996 6.3309 1.8816 8.8889
MZ-MEL-2 GDSC2 3.4874 5.77 2.2329 6.4285
IPC-298 GDSC2 3.5149 4.785 2.7444 3.1327
M14 GDSC2 3.55 8.832 0.7546 15.2591
WM278 GDSC2 3.6079 8.1553 1.1392 12.8645
DJM-1 GDSC2 3.6335 7.1379 1.667 9.5814
COLO 783 GDSC2 3.656 6.7566 1.8745 8.2284
WM793 GDSC2 3.6835 13.1584 -1.2983 24.4421
MeWo GDSC2 3.7545 5.7489 2.4473 4.3998
A-375 GDSC2 3.7553 7.0221 1.8194 8.3115
Mel JuSo GDSC2 3.7779 5.7064 2.485 4.1111
CP66-MEL GDSC2 3.8097 6.6344 2.0526 6.7218
SK-MEL-5 GDSC2 3.9202 6.7859 2.0597 6.4075
MMAc-SF GDSC2 3.9859 6.0164 2.4798 3.6822
VMRC-MELG GDSC2 4.1058 8.0454 1.5773 8.9206
451Lu GDSC2 4.1616 6.7258 2.2587 4.6452
COLO 800 GDSC2 4.4015 13.3557 -0.8261 20.6537
WT2-iPS GDSC2 4.6109 10.2936 0.8432 11.9875
RVH-421 GDSC2 4.6787 9.1307 1.4558 8.3288
SK-MEL-2 GDSC2 4.789 6.1847 2.8508 0.6036
CHL-1 GDSC2 4.8246 13.8513 -0.7489 19.2675
Hs 940.T GDSC2 4.8393 6.8826 2.5906 1.6669
LB373-MEL-D GDSC2 4.8402 6.2236 2.8579 0.5426
LB2518-MEL GDSC2 4.8847 6.9518 2.5845 1.6416
UACC-257 GDSC2 6.0642 12.8368 0.6096 10.1479
UACC-62 GDSC2 6.498 20.0395 -2.5605 22.0336
COLO 829 GDSC2 6.5395 17.3644 -1.2324 17.423
EquiPSC Line K2 GDSC2 3.5809 8.2507 1.0699 13.3501
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 3.8015 15.2875 -2.2661 27.3396
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Rh41 GDSC2 -1.793 2.9309 -2.1584 51.0902
Rh30 GDSC2 0.1334 3.7037 -0.2691 33.8915
G-401 GDSC2 1.2186 7.0164 -0.4768 29.6449
MES-SA GDSC2 2.2861 7.1324 0.497 20.7611
Hs 633.T GDSC2 2.2953 3.6738 2.089 11.4224
KYM-1 GDSC2 3.6575 8.2038 1.1547 12.6346
A-204 GDSC2 3.785 10.4172 0.1524 17.8191
STS-0421 GDSC2 4.0111 7.244 1.9014 7.1671
EW-8 GDSC2 4.0273 6.28 2.3814 4.189
RD GDSC2 4.2848 11.6499 -0.0693 17.5631
SW872 GDSC2 4.4444 7.3312 2.1578 4.6716
MFH-ino GDSC2 4.823 10.337 0.9729 10.7744
GCT GDSC2 4.8819 12.3613 0.0272 15.6023
RKN GDSC2 4.9086 7.0154 2.5698 1.6831
TE 441.T GDSC2 5.0496 13.1007 -0.213 16.3492
SW684 GDSC2 5.0777 15.3959 -1.3216 20.9412
VA-ES-BJ GDSC2 5.1045 17.4562 -2.3202 24.2841
HT-1080 GDSC2 5.1484 6.9188 2.7227 0.7975
SW982 GDSC2 5.1563 13.0018 -0.0875 15.51
G-402 GDSC2 5.3488 20.0465 -3.4171 26.7879
SK-UT-1 GDSC2 6.0627 13.6872 0.2069 12.1494
SK-LMS-1 GDSC2 6.8558 16.1558 -0.4429 13.5929
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 GDSC2 -0.9793 6.0524 -2.3226 45.5532
23132/87 GDSC2 0.3721 8.7473 -2.1192 38.4735
AGS GDSC2 0.6094 10.0115 -2.4852 38.2571
NCI-N87 GDSC2 1.1937 10.4481 -2.1398 35.1983
MKN45 GDSC2 1.4616 11.0113 -2.1652 34.2748
IM95 GDSC2 1.9358 7.0848 0.1893 23.6722
TMK-1 GDSC2 2.5056 8.3851 0.0816 22.1545
Fu97 GDSC2 2.9757 7.1432 1.1156 14.8904
SNU-1 GDSC2 3.0719 5.1014 2.2161 7.7638
OCUM-1 GDSC2 3.332 10.0444 -0.0309 20.0501
GCIY GDSC2 3.3675 7.5858 1.2279 13.022
Hs 746.T GDSC2 3.3691 9.6206 0.2118 18.7209
KATO III GDSC2 3.5732 8.8817 0.7486 15.2263
RERF-GC-1B GDSC2 3.5869 8.2542 1.073 13.3154
MKN28 GDSC2 3.7141 6.7491 1.9232 7.7721
RF-48 GDSC2 4.0386 9.9612 0.579 14.8821
SK-GT-2 GDSC2 4.052 10.8219 0.1616 17.0385
MKN1 GDSC2 4.1594 11.6191 -0.1511 18.2864
ECC12 GDSC2 4.2044 9.018 1.1717 11.0987
ECC10 GDSC2 4.2372 8.5002 1.4503 9.3688
SCH GDSC2 4.4351 9.8403 0.9375 11.8806
NUGC-4 GDSC2 4.559 7.5811 2.1139 4.7072
TGBC11TKB GDSC2 4.6964 10.6734 0.7192 12.4676
SNU-5 GDSC2 5.148 18.2682 -2.6893 25.2812
HSC-39 GDSC2 5.7954 7.6999 2.6965 0.4873
MKN7 GDSC2 5.8385 17.0169 -1.5583 20.0942
NUGC-3 GDSC2 6.2765 17.5084 -1.4853 18.9036
SNG-M GDSC2 4.2546 8.0183 1.6983 7.8348
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
K5 GDSC2 3.33 9.6678 0.1557 19.1252
KMH-2 GDSC2 3.7769 6.5179 2.0855 6.5982
IHH-4 GDSC2 3.9638 12.476 -0.7318 21.4222
FTC-133 GDSC2 4.012 13.3162 -1.1124 22.8323
CGTH-W-1 GDSC2 4.3001 6.2709 2.5609 2.6078
TT GDSC2 4.303 6.282 2.5576 2.6211
CAL-62 GDSC2 4.7498 10.1308 1.0216 10.6666
HTC-C3 GDSC2 4.7814 9.4096 1.3918 8.4794
8505C GDSC2 4.9691 8.306 2.0321 4.4307
B-CPAP GDSC2 5.0836 14.4354 -0.8437 19.0407
8305C GDSC2 5.223 7.0834 2.6914 0.8552
ASH-3 GDSC2 5.3102 12.2089 0.4065 12.7245
WRO GDSC2 5.4617 15.5481 -1.1125 19.2493
BHT-101 GDSC2 5.6072 13.6884 -0.1024 14.5724
ML-1 [Human leukemia] GDSC2 5.8047 7.4697 2.7825 0.2819
TT2609-C02 GDSC2 5.8971 11.4603 1.1461 7.6646
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HO-1-u-1 GDSC2 -2.9058 3.0874 -3.412 58.9566
BB49-HNC GDSC2 0.4372 7.0092 -1.2578 35.9524
DOK GDSC2 0.8091 7.3495 -1.0379 33.5505
UPCI-SCC-090 GDSC2 1.1498 7.0177 -0.5457 30.2224
PCI-15A GDSC2 1.3923 4.8503 0.6656 23.3318
HSC-2 GDSC2 1.9272 6.5154 0.4533 22.3274
KOSC-2 GDSC2 1.9606 8.5569 -0.5016 26.8123
Detroit 562 GDSC2 1.9912 9.7112 -1.0397 28.8469
SAT [Human HNSCC] GDSC2 2.1026 9.4732 -0.8208 27.609
OSC-19 GDSC2 2.2067 8.3083 -0.1524 24.3423
JHU-011 GDSC2 2.2141 10.8267 -1.3895 29.3098
BICR 10 GDSC2 2.3712 11.244 -1.4568 29.0093
KON GDSC2 3.1325 10.5899 -0.4711 22.7123
PCI-04B GDSC2 3.1947 10.8284 -0.5378 22.8144
SCC-9 GDSC2 3.3187 7.4767 1.2419 13.0812
HO-1-N-1 GDSC2 3.4561 5.9452 2.1204 7.2246
NCI-H3118 GDSC2 3.4708 5.4998 2.3545 5.7058
BB30-HNC GDSC2 3.6326 8.5705 0.9518 13.8955
CAL-33 GDSC2 3.6781 8.7213 0.913 13.9921
HSC-3 GDSC2 3.7276 11.1802 -0.2744 20.0546
JHU-029 GDSC2 3.8061 8.1356 1.3057 11.3277
JHU-022 GDSC2 3.9354 13.1185 -1.0749 22.8944
LB771-HNC GDSC2 3.9956 11.3155 -0.1282 18.6187
BICR 22 GDSC2 4.0898 10.7126 0.2454 16.5101
BICR 78 GDSC2 4.2121 6.617 2.3441 4.0303
SCC-4 GDSC2 4.3713 9.4631 1.0759 11.2456
SCC-15 GDSC2 4.4726 9.3734 1.1933 10.3248
BHY GDSC2 4.4794 6.8195 2.4177 3.106
SCC-25 GDSC2 4.5267 6.9394 2.3913 3.1736
OSC-20 GDSC2 4.6881 10.8679 0.618 13.0354
PCI-06A GDSC2 4.7131 11.3642 0.393 14.1652
PE/CA-PJ15 GDSC2 4.87 7.2255 2.4593 2.2791
BICR 31 GDSC2 4.9119 9.3508 1.5074 7.5389
Ca9-22 GDSC2 4.928 14.6346 -1.0581 20.2809
SKN-3 GDSC2 5.0279 10.2178 1.1712 9.2145
PCI-30 GDSC2 5.1791 8.884 1.8939 4.8405
HSC-4 GDSC2 5.2767 15.1559 -1.0555 19.4473
SAS GDSC2 5.4216 13.8855 -0.3287 16.0262
CAL-27 GDSC2 6.3471 15.4048 -0.4223 14.486
FaDu GDSC2 8.8838 20.4831 -1.1856 13.121
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-29 GDSC2 2.0952 8.7094 -0.4519 26.1032
HT-1197 GDSC2 3.3685 18.1233 -4.04 32.7912
KU-19-19 GDSC2 3.4263 7.0392 1.5495 10.8858
639V GDSC2 4.0027 12.0537 -0.4904 20.2705
647V GDSC2 4.2162 6.4338 2.4332 3.4959
UM-UC-3 GDSC2 4.3146 8.2252 1.6402 8.0472
SW1710 GDSC2 4.5865 11.1882 0.3865 14.5072
SW780 GDSC2 4.8558 6.7492 2.6549 1.3475
BFTC-905 GDSC2 5.0071 14.4304 -0.8981 19.4462
5637 GDSC2 5.0899 8.2768 2.1167 3.7643
HT-1376 GDSC2 5.221 12.4147 0.2445 13.7424
RT-4 GDSC2 5.4288 8.4114 2.2444 2.6148
TCCSUP GDSC2 5.4777 11.422 0.8968 9.7958
T24 GDSC2 6.0436 7.9975 2.6849 0.4087
RT-112 GDSC2 6.1878 15.7599 -0.701 16.0057
J82 GDSC2 7.2944 15.3598 0.2031 9.9316
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ME-180 GDSC2 -0.403 9.653 -3.3074 43.7669
PA-1 GDSC2 0.0483 6.0702 -1.2497 37.8328
C-33 A GDSC2 0.799 8.847 -1.7478 35.7468
CAL-39 GDSC2 1.3845 6.568 -0.1045 27.2982
DSH1 GDSC2 2.1137 6.7121 0.5384 21.1652
OMC-1 [Human cervical carcinoma] GDSC2 2.1573 6.7949 0.5398 20.9964
BPH-1 GDSC2 2.3725 8.4515 -0.0715 23.3678
Ca Ski GDSC2 2.5811 10.0072 -0.6565 25.2851
SW954 GDSC2 2.6603 5.1341 1.8189 11.629
KGN GDSC2 2.6757 4.4378 2.1637 9.4567
DoTc2 4510 GDSC2 3.2366 12.0427 -1.1098 25.0272
JAR GDSC2 3.4163 5.4882 2.3164 6.0974
TC-YIK GDSC2 3.6008 7.733 1.3443 11.6527
NT2-D1 GDSC2 3.674 5.6668 2.4284 4.7125
NEC8 GDSC2 3.7574 15.2495 -2.283 27.5073
OVCA420 GDSC2 3.8488 8.1144 1.3494 10.9516
SKN GDSC2 3.9132 10.5798 0.1732 17.358
JHOS-3 GDSC2 4.0556 6.4847 2.3024 4.6074
PWR-1E GDSC2 4.063 10.4633 0.3485 16.0475
OVMIU GDSC2 4.1039 8.5267 1.339 10.3596
ACC-OV7 GDSC2 4.1904 14.3484 -1.4853 23.751
OVCA433 GDSC2 4.2581 9.1565 1.1433 11.1316
C-4-I GDSC2 4.3046 9.3726 1.0714 11.4341
OV17R GDSC2 4.324 8.4597 1.5328 8.67
SiSo GDSC2 4.3966 6.6094 2.464 2.988
UWB1.289 GDSC2 4.5087 11.5917 0.1296 16.0115
SKG-IIIa GDSC2 4.5492 17.2529 -2.649 26.5635
JEG-3 GDSC2 4.6108 7.4452 2.2098 4.056
SW756 GDSC2 4.6281 7.7267 2.0896 4.717
PEO1 GDSC2 4.6348 12.0963 -0.025 16.4575
HEY GDSC2 4.6732 8.8642 1.58 7.6133
MS751 GDSC2 4.889 10.2177 1.0765 10.0464
LB831-BLC GDSC2 4.8986 12.3588 0.0406 15.497
HeLa GDSC2 4.9641 13.6598 -0.5504 18.0769
NCC-IT GDSC2 5.0647 12.3395 0.1702 14.4691
SiHa GDSC2 5.1434 6.8522 2.7464 0.7162
HEC-1 GDSC2 5.2088 7.0436 2.7006 0.8322
HT-3 GDSC2 5.5135 7.3961 2.6955 0.6415
SW962 GDSC2 5.5774 7.6589 2.6224 0.8409
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

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