Details of the Drug

General Information of Drug (ID: DMSIM4Y)

Drug Name

TL-77

Synonyms

CHEMBL3261266; TL-77; GTPL7834; SCHEMBL15124009; SCHEMBL15124011; HEBBDGMHRHUJRY-VOTSOKGWSA-N; BDBM50011472; (E)-N-(2-methoxy-5-((2,4,6-trimethoxystyrylsulfonyl)methyl)pyridin-3-yl)methanesulfonamide; N-[5-[[(E)-2-(2,4,6-Trimethoxyphenyl)ethenyl]sulfonyl]methyl-2-methoxypyridine-3-yl]methanesulfonamide

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
------------------------------------------------------------------------------------

Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

Chemical Identifiers

Formula: C19H24N2O8S2
Canonical SMILES: COC1=CC(=C(C(=C1)OC)C=CS(=O)(=O)CC2=CC(=C(N=C2)OC)NS(=O)(=O)C)OC
InChI: 1S/C19H24N2O8S2/c1-26-14-9-17(27-2)15(18(10-14)28-3)6-7-31(24,25)12-13-8-16(21-30(5,22)23)19(29-4)20-11-13/h6-11,21H,12H2,1-5H3/b7-6+
InChIKey: HEBBDGMHRHUJRY-VOTSOKGWSA-N

Cross-matching ID

PubChem CID: 54759259
TTD ID: D05XPV

References

1	Discovery of (E)-3-((styrylsulfonyl)methyl)pyridine and (E)-2-((styrylsulfonyl)methyl)pyridine derivatives as anticancer agents: synthesis, structure-activity relationships, and biological activities. J Med Chem. 2014 Mar 27;57(6):2275-91.