Details of the Drug

General Information of Drug (ID: DMSO02K)

Drug Name
AMT-061
Synonyms etranacogene dezaparvovec
Indication
Disease Entry ICD 11 Status REF
Haemophilia B 3B11.0 Phase 3 [1]
Affected Organisms
Humans and other mammals
Drug Type
Gene therapy
Cross-matching ID
UNII
Z5XCD5Q9RL
DrugBank ID
DB16791
TTD ID
DBHO19

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor IX (F9) TTFEZ5Q FA9_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Haemophilia B
ICD Disease Classification 3B11.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Coagulation factor IX (F9) DTT F9 5.69E-01 -0.13 -0.45
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03569891) HOPE-B: Trial of AMT-061 in Severe or Moderately Severe Hemophilia B Patients. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of uniQure.