Details of the Drug

General Information of Drug (ID: DMSUZFO)

• Drug Name: NH-4
• Synonyms: ammonium; Ammonium ion; Ammonium(1+); azanium; NH4+; Ammonium cation; 14798-03-9; Ammonia ion; Ammonium ion(+); AMMONIUM CATION WITH D; UNII-54S68520I4; NH4(+); 54S68520I4; Ammonium Compounds; ND4; Quaternary ammonium compounds; Nitrogen cation; Ammonium(+); nitrogen(1+); Nitrogen tetrahydride; Ammonium ion(1+); Ammonium (NH4+); AC1NUTFY; AC1NUTFO; Ammonia ion (NH4+); Ammonium ion (NH4+); nitrogen(1+) trihydride; Ammonium (8CI,9CI); Ammonia, ion (NH41+); AC1Q1W88; AC1L18R7; DTXSID5043974; CHEBI:29352; CHEBI:28938; CTK0H5427

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 18.039
  Logarithm of the Partition Coefficient (xlogp); -0.7
  Rotatable Bond Count (rotbonds); 0
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 0
• Chemical Identifiers:
  Formula: H4N+
  IUPAC Name: azanium
  Canonical SMILES: [NH4+]
  InChI: InChI=1S/H3N/h1H3/p+1
  InChIKey: QGZKDVFQNNGYKY-UHFFFAOYSA-O
• Cross-matching ID:
  PubChem CID: 223
  ChEBI ID: CHEMBL28938
  CAS Number: 14798-03-9
  TTD ID: D0E2IR

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Thyroid hormone receptor (THR)	TTQWUPT	NOUNIPROTAC	Antagonist	[1]

References

• [1] Design of thyroid hormone receptor antagonists from first principles. J Steroid Biochem Mol Biol. 2002 Dec;83(1-5):59-73.