Details of the Drug

General Information of Drug (ID: DMT0YQI)

Drug Name
8-chloro-adenosine
Synonyms Nucleoside analogs (cancer); Nucleoside analogs (cancer), MD Anderson Cancer Center; 8-Cl-Ado
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1/2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C10H12ClN5O4
Canonical SMILES
C1=NC(=C2C(=N1)N(C(=N2)Cl)C3C(C(C(O3)CO)O)O)N
InChI
InChI=1S/C10H12ClN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)/t3-,5-,6-,9-/m1/s1
InChIKey
MHDPPLULTMGBSI-UUOKFMHZSA-N
Cross-matching ID
PubChem CID
147569
CAS Number
34408-14-5
UNII
PA05MFH3I7
DrugBank ID
DB16075
TTD ID
D03OVA
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

References

1 ClinicalTrials.gov (NCT02509546) 8-Chloro-Adenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia.