Details of the Drug

General Information of Drug (ID: DMT0YQI)

Drug Name
8-chloro-adenosine
Synonyms Nucleoside analogs (cancer); Nucleoside analogs (cancer), MD Anderson Cancer Center; 8-Cl-Ado
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1/2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C10H12ClN5O4
Canonical SMILES
C1=NC(=C2C(=N1)N(C(=N2)Cl)C3C(C(C(O3)CO)O)O)N
InChI
1S/C10H12ClN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)/t3-,5-,6-,9-/m1/s1
InChIKey
MHDPPLULTMGBSI-UUOKFMHZSA-N
Cross-matching ID
PubChem CID
147569
CAS Number
34408-14-5
UNII
PA05MFH3I7
DrugBank ID
DB16075
TTD ID
D03OVA
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

References

1 ClinicalTrials.gov (NCT02509546) 8-Chloro-Adenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia.