Details of the Drug

General Information of Drug (ID: DMT7K0U)

Drug Name
Glutamine Hydroxamate
Synonyms
glutamine hydroxamate; N-Hydroxy-L-glutamine; 1955-67-5; Glutamyl-gamma-hydroxamate; gamma-Glutamyl hydroxamate; Glutamate-gamma-hydroxamate; L-gamma-Glutamyl hydroxamate; Glutamate-gamma-hydroxamic acid; Glutamic acid gamma-monohydroxamate; CHEMBL63893; CHEBI:75305; HGA; Glunhoh; Amino acid hydroxamates L-glutamic acid gamma- monohydroxamate; AC1L9MTD; gamma-glutamylhydroxylamine; SCHEMBL4321249; L-Glutamic acid -monohydroxamate; L-Glutamic acid gamma-hydroxamate; ZINC2522574; FCH838713; BDBM50129196; L-glutamic acid gamma-hydr
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 162.14
Logarithm of the Partition Coefficient (xlogp) -4.4
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 4
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C5H10N2O4
IUPAC Name
(2S)-2-amino-5-(hydroxyamino)-5-oxopentanoic acid
Canonical SMILES
C(CC(=O)NO)[C@@H](C(=O)O)N
InChI
InChI=1S/C5H10N2O4/c6-3(5(9)10)1-2-4(8)7-11/h3,11H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChIKey
YVGZXTQJQNXIAU-VKHMYHEASA-N
Cross-matching ID
PubChem CID
449178
ChEBI ID
CHEMBL75305
CAS Number
1955-67-5
DrugBank ID
DB02446
TTD ID
D0G9LM
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial Glucosamine-6-phosphate synthase (Bact glmS) TTC67I0 GLMS_ECOLI Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.