Details of the Drug

General Information of Drug (ID: DMTEJJT)

• Drug Name: Doranidazole
• Synonyms: PR-000350; PR-350; RP-343; Doranidazole; Rac-(2RS,3SR)-3-(2-Nitro-1H-imidazol-1-ylmethoxy)butane-1,2,4-triol

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 3	[1]

• Drug Type: Small molecular drug
• Chemical Identifiers:
  Formula: C8H13N3O6
  Canonical SMILES: C1=CN(C(=N1)[N+](=O)[O-])COC(CO)C(CO)O
  InChI: 1S/C8H13N3O6/c12-3-6(14)7(4-13)17-5-10-2-1-9-8(10)11(15)16/h1-2,6-7,12-14H,3-5H2/t6-,7+/m1/s1
  InChIKey: FIITXXIVUIXYMI-RQJHMYQMSA-N
• Cross-matching ID:
  PubChem CID: 164486
  CAS Number: 149838-23-3
  UNII: 911XR034RX
  DrugBank ID: DB17304
  TTD ID: D0Y2IN

References

• [1] Efficacy of novel hypoxic cell sensitiser doranidazole in the treatment of locally advanced pancreatic cancer: long-term results of a placebo-controlled randomised study. Radiother Oncol. 2008 Jun;87(3):326-30.