Details of the Drug

General Information of Drug (ID: DMTV4L7)

Drug Name
CHS-828
Synonyms Cancer therapeutics, LEO Pharma; GMX-1778
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1/2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 371.9
Logarithm of the Partition Coefficient (xlogp) 4.3
Rotatable Bond Count (rotbonds) 11
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C19H22ClN5O
IUPAC Name
2-[6-(4-chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine
Canonical SMILES
C1=CC(=CC=C1OCCCCCCN=C(NC#N)NC2=CC=NC=C2)Cl
InChI
InChI=1S/C19H22ClN5O/c20-16-5-7-18(8-6-16)26-14-4-2-1-3-11-23-19(24-15-21)25-17-9-12-22-13-10-17/h5-10,12-13H,1-4,11,14H2,(H2,22,23,24,25)
InChIKey
BOIPLTNGIAPDBY-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
148198
ChEBI ID
CHEBI:95016
CAS Number
200484-11-3
UNII
8LAP87DNSZ
DrugBank ID
DB12980
TTD ID
D0Y1NC
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Nicotinamide phosphoribosyltransferase (NAMPT) TTD1WIG NAMPT_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Nicotinamide phosphoribosyltransferase (NAMPT) DTT NAMPT 3.06E-08 -0.63 -0.59
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 147 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -6.1792 -2.8659 -6.3346 29.7625
MEC1 CTRP2 -5.9765 -5.1736 -5.9765 28.2474
JM1 CTRP2 -8.6502 -5.1481 -8.6913 46.1332
SET-2 CTRP2 -11.2276 -10.7548 -11.2276 63.234
EoL-1 CTRP2 -11.2185 -10.5371 -11.2185 63.1732
GA-10 CTRP2 -11.2151 -10.6945 -11.2151 63.151
697 CTRP2 -11.2061 -10.6966 -11.2061 63.0906
ST486 CTRP2 -11.1828 -10.6084 -11.1828 62.9354
SUP-B15 CTRP2 -11.1681 -9.0415 -11.1683 62.8181
Daudi CTRP2 -11.1075 -10.4595 -11.1075 62.4337
HH [Human lymphoma] CTRP2 -11.0163 -8.941 -11.0164 61.8118
MOLT-3 CTRP2 -10.7798 -9.7034 -10.7798 60.2502
M-07e CTRP2 -10.1679 -9.7098 -10.1679 56.1733
SEM CTRP2 -10.1638 -9.4629 -10.1638 56.1464
CA46 CTRP2 -9.8586 -8.1869 -9.8587 54.1123
OCI-AML-3 CTRP2; CTRP1 -9.4149 -8.2025 -9.4149 51.1564
NOMO-1 CTRP2; CTRP1 -9.4096 -8.3246 -9.4096 50.7413
KHM-1B CTRP2 -8.9089 0.3606 -10.2358 48.157
KO52 CTRP2 -8.6141 -3.056 -8.9276 46.2339
Kasumi-2 CTRP2 -8.4061 -6.9262 -8.4061 44.435
OCI-Ly19 CTRP2 -8.1228 -6.3621 -8.1233 42.549
MOTN-1 CTRP2 -8.0912 -4.1824 -8.1884 42.5741
Namalwa CTRP2 -8.0856 -7.1665 -8.0856 42.2994
HEL 92.1.7 CTRP2 -7.9182 -7.3503 -7.9182 41.184
F-36P CTRP2 -7.8437 -5.9356 -7.8452 40.6926
SU-DHL-5 CTRP1 -7.6579 -7.0568 -7.6579 81.6004
EB1 CTRP2 -7.5646 -6.2602 -7.5646 38.8283
TF-1 CTRP2 -7.5167 -6.6744 -7.5167 38.5089
Pfeiffer CTRP2 -7.5086 -5.4985 -7.5119 38.4658
RS4;11 CTRP2 -7.4866 -6.5823 -7.4866 37.9427
CMK CTRP2 -7.4649 -6.7547 -7.4649 38.1641
DoHH2 CTRP2 -7.4256 -5.8204 -7.4262 37.5383
JeKo-1 CTRP2 -7.3279 -6.8063 -7.3279 37.2514
Reh CTRP2 -7.3003 -6.5445 -7.3003 36.7026
Mino CTRP2 -7.2122 -6.696 -7.2122 36.4805
OCI-AML-5 CTRP2 -7.192 -6.8049 -7.192 36.3459
PF-382 CTRP2 -7.1901 -6.3993 -7.1901 35.9689
A4/Fukuda CTRP2 -7.1576 -6.3923 -7.1576 36.1164
NALM-6 CTRP2 -7.1151 -5.6633 -7.1155 35.4713
OPM-2 CTRP2 -7.1143 -5.9826 -7.1143 35.8282
HD-MY-Z CTRP2 -7.0612 -6.5299 -7.0612 35.4741
KMS-26 CTRP2 -7.0383 -6.4698 -7.0383 34.9588
P12-Ichikawa CTRP2 -6.9623 -6.1926 -6.9623 34.4527
OCI-M1 CTRP2 -6.9594 -5.1621 -6.9621 34.805
BL-70 CTRP2; CTRP1 -6.9134 -6.2733 -6.9134 54.9074
DB CTRP2 -6.8019 -5.9217 -6.8019 33.7467
Granta-519 CTRP2 -6.6466 -4.4559 -6.661 32.7596
NU-DHL-1 CTRP2 -6.5735 -3.3963 -6.6721 32.5505
SU-DHL-8 CTRP2 -6.5128 -5.261 -6.5131 31.4621
BV-173 CTRP2 -6.4939 -5.3294 -6.4941 31.336
A3/Kawakami CTRP2 -6.4877 -5.8685 -6.4877 31.6531
SIG-M5 CTRP2 -6.3998 -5.074 -6.4003 31.0689
MOLM-6 CTRP2 -6.3949 -4.8853 -6.3965 30.6816
RPMI-8402 CTRP2 -6.372 -5.6787 -6.372 30.5237
MHH-CALL-4 CTRP2 -6.296 -4.7463 -6.2983 30.0259
SUP-T1 CTRP2 -6.2674 -5.3871 -6.2674 29.8279
OCI-AML-2 CTRP2 -6.2312 -5.7693 -6.2312 29.5866
OCI-Ly3 CTRP2 -6.2158 -5.2551 -6.2159 29.8418
NCO2 CTRP2 -6.177 -3.9613 -6.2026 29.3118
RL CTRP2 -6.1299 -5.6457 -6.1299 29.2692
KM-H2 CTRP2 -6.1295 -5.076 -6.1305 23.5685
JJN-3 CTRP2 -6.1164 -5.5633 -6.1164 29.1791
L-428 CTRP2 -6.0629 -5.1835 -6.0629 28.8228
Ci-1 CTRP2 -6.0574 -5.6287 -6.0574 28.7859
KMS-20 CTRP2 -6.0274 -4.2266 -6.036 28.6149
MOLT-16 CTRP2 -5.9403 -5.147 -5.9403 27.6507
K-562 CTRP2 -5.7903 -4.4655 -5.7917 27.0111
KE-37 CTRP2 -5.7427 -4.4041 -5.7445 26.3415
CML-T1 CTRP2 -5.5754 -4.3269 -5.5769 25.2271
MOLM-16 CTRP2; CTRP1 -5.5294 -4.533 -5.5296 24.9167
WSU-DLCL2 CTRP2; CTRP1 -5.4882 -4.7055 -5.4882 24.6416
Peer CTRP2 -5.4711 -4.8315 -5.4711 24.5279
NCI-H929 CTRP2 -5.3641 -4.3997 -5.3643 23.8162
P31/FUJ CTRP2 -5.3473 -4.8806 -5.3473 23.7041
KMS-27 CTRP2 -5.341 -4.8192 -5.341 23.6621
SU-DHL-6 CTRP2 -5.2974 -4.0379 -5.2999 23.3803
HPB-ALL CTRP2 -5.2954 -4.7553 -5.2954 23.3585
EM-2 CTRP2 -5.2902 -4.5124 -5.2902 23.3238
HEL CTRP2 -5.2203 -4.4188 -5.2204 22.8588
LAMA-84 CTRP2 -5.1687 -2.7335 -5.4105 17.6015
NB4 CTRP2 -5.1681 -4.7573 -5.1681 22.5114
SU-DHL-10 CTRP2 -5.119 -4.6043 -5.119 22.1843
Karpas-422 CTRP2 -5.1063 -4.7141 -5.1063 22.4494
MM1.S CTRP2 -5.0867 -4.0616 -5.0875 21.9721
HT CTRP2; CTRP1 -5.0095 -4.355 -5.0095 46.0387
RPMI-6666 CTRP2 -4.9183 -3.9346 -4.9191 21.1992
Ku812 CTRP2; CTRP1 -4.9039 -0.7244 -4.924 45.5853
MOLP-8 CTRP2 -4.8975 -0.1277 -5.7285 24.028
SKM-1 CTRP2; CTRP1 -4.8057 -4.0399 -4.8058 20.0993
JURL-MK1 CTRP2 -4.7595 -3.8971 -4.7599 19.7927
Hs 611.T CTRP2 -4.7191 -0.2569 -5.4885 22.6377
LP-1 CTRP2; CTRP1 -4.7034 -2.9949 -4.737 19.878
SU-DHL-4 CTRP2; CTRP1 -4.5312 -3.8724 -4.5312 18.2721
SUP-HD1 CTRP2 -4.5158 -2.2014 -4.6566 18.9996
KYO-1 CTRP2 -4.4243 -3.8522 -4.4243 17.5605
Raji CTRP2 -4.3895 -3.7171 -4.3897 17.3297
U-937 CTRP2; CTRP1 -4.3503 -3.7018 -4.3504 17.0682
HDLM-2 CTRP2 -4.3497 -2.1428 -4.4951 17.5652
HuT 78 CTRP2 -4.3213 0.0161 -5.1738 20.339
KMS-34 CTRP2 -4.2091 -2.8136 -4.2365 16.2204
SR CTRP2 -4.1853 -3.078 -4.1938 15.9984
L-540 CTRP2 -4.1727 -3.2967 -4.1747 15.8924
MC116 CTRP2; CTRP1 -4.1071 -3.6985 -4.1071 41.9124
AMO1 CTRP2; CTRP1 -4.1013 -2.6736 -4.1372 15.5318
Jurkat CTRP2 -4.0289 8.2692 -9.4119 28.3693
P3HR-1 CTRP2; CTRP1 -3.897 -1.8339 -3.8971 40.9518
PL21 CTRP2; CTRP1 -3.8969 -0.5673 -4.5079 16.2852
MOLT-13 CTRP2 -3.8783 -2.0358 -4.0063 14.3686
OCI-Ly10 CTRP2; CTRP1 -3.7693 -2.0106 -3.8866 13.9463
KE-97 CTRP2; CTRP1 -3.6578 -2.9008 -3.6578 39.858
RPMI-8226 CTRP2; CTRP1 -3.6476 -2.9227 -3.65 12.3992
KCL-22 CTRP2 -3.6157 7.605 -8.0816 27.7179
JVM-3 CTRP2 -3.5913 -1.5517 -3.8248 12.842
NU-DUL-1 CTRP2; CTRP1 -3.4745 -2.79 -3.4772 11.2481
Kasumi-1 CTRP2 -3.3674 1.1273 -4.6819 15.9142
Karpas-299 CTRP2 -3.3615 -2.7718 -3.363 10.492
Ri-1 CTRP2 -3.3457 -1.5547 -3.5565 11.1287
KMS-12-BM CTRP2 -3.2469 -0.9019 -3.6858 11.3337
EHEB CTRP2 -3.0499 -1.9302 -3.1288 8.6854
U266B1 CTRP2 -2.6647 1.5805 -4.2206 12.3725
HL-60 CTRP2 -1.5683 2.7981 -3.8655 8.6212
L-363 CTRP2 -1.5323 0.8619 -2.9048 4.2322
THP-1 CTRP2; CTRP1 -1.5226 0.898 -2.9152 4.2587
KMS-28BM CTRP2 -1.4241 1.2046 -2.9913 4.406
EJM CTRP2; CTRP1 -1.2349 1.7895 -3.1012 4.8358
MHH-CALL-3 CTRP2 -0.6934 2.7322 -3.2121 4.1808
AML-193 CTRP2 -0.6917 4.272 -3.9211 7.3378
SUP-M2 CTRP2 -0.2106 7.0751 -4.9447 10.6586
KMS-11 CTRP2; CTRP1 -0.0012 3.7581 -3.2494 3.4366
SU-DHL-1 CTRP2 0.0798 2.1855 -2.5162 0.851
Toledo CTRP2 0.1469 11.1242 -6.673 16.2719
ME1 CTRP2 0.4535 2.6466 -2.5293 0.6697
DEL CTRP2 0.4576 1.5852 -2.1448 0.0429
MOLP-2 CTRP2 0.4588 2.3373 -2.4089 0.3977
SUP-T11 CTRP2 0.4647 2.6239 -2.5155 0.6307
KMM-1 CTRP2 0.4713 4.3088 -3.2212 2.8201
Ki-JK CTRP2 0.4898 2.9594 -2.6368 0.9278
KMS-18 CTRP2 0.5924 4.3918 -3.1903 2.593
RCH-ACV CTRP2 0.6783 2.5353 -2.3943 0.2968
REC-1 CTRP2 0.6848 2.8755 -2.5179 0.5347
MV4-11 CTRP2 0.8051 2.4744 -2.3249 0.1643
SK-MM-2 CTRP2 0.8466 2.8579 -2.4458 0.3341
Karpas-620 CTRP2 0.8854 2.2903 -2.2339 0.0647
GDM-1 CTRP2; CTRP1 0.998 3.3294 -2.5591 0.4945
TALL-1 [Human adult T-ALL] CTRP2 1.0774 3.3175 -2.5228 0.3973
Mono-Mac-1 CTRP2 1.4348 3.9568 -2.6157 0.4485
Mono-Mac-6 CTRP2 1.9322 4.4894 -2.6162 0.3111
⏷ Show the Full List of 147 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 -6.3249 -5.6396 -6.3249 30.2107
TE15 CTRP2 1.341 3.3588 -2.3895 0.2106
EC-GI-10 CTRP2 -7.2962 -6.1345 -7.2962 37.0402
KYSE-30 CTRP2 -6.2193 -5.824 -6.2193 29.8651
OE19 CTRP2 -6.053 -5.5085 -6.053 28.7566
KYSE-510 CTRP2 -5.9799 -5.3519 -5.9799 28.2696
TE-14 CTRP2 -5.8944 -4.1519 -5.9027 27.7277
KYSE-520 CTRP2 -5.5604 -2.965 -5.6498 25.7776
TE-6 CTRP2 -5.3354 -4.0539 -5.338 23.6334
KYSE-450 CTRP2; CTRP1 -5.0546 -3.8233 -5.0546 46.3824
OE21 CTRP2 -4.8876 -2.8222 -4.9512 21.2076
KYSE-180 CTRP2 -4.6209 -3.5847 -4.6232 18.877
TE-11 CTRP2 -4.217 -2.5642 -4.2707 16.7063
OE33 CTRP2 -4.0684 -3.0947 -4.073 15.5493
TE-1 CTRP2 -4.044 -2.8835 -4.0585 15.0778
COLO 680N CTRP2 -3.8463 -2.8165 -3.8577 13.7518
TE-5 CTRP2 -3.7934 -1.8468 -3.9522 14.2545
KYSE-70 CTRP2 -3.1705 -2.387 -3.1848 9.2637
TE-10 CTRP2 -3.1583 -2.1535 -3.2017 9.2823
TE-9 CTRP2 -3.134 -2.5405 -3.1377 8.9852
KYSE-140 CTRP2; CTRP1 -2.3879 -1.5109 -2.3879 34.0511
TE-4 CTRP2 -2.3217 -0.3797 -2.9736 6.1268
KYSE-410 CTRP2; CTRP1 -1.5303 0.2534 -1.5308 30.1309
KYSE-150 CTRP2 0.8437 2.3493 -2.2198 0.1044
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 -5.2607 -4.6116 -5.2607 23.4776
PSN1 CTRP2 -6.2923 -5.7066 -6.2923 30.3511
PaTu 8988t CTRP2 -6.0307 -3.8258 -6.0581 28.6999
L3.3 CTRP2 -6.0295 -5.4756 -6.0295 28.2445
Hs 766T CTRP2 -6.0224 -3.2928 -6.0989 28.8105
Panc 02.03 CTRP2 -5.9603 -4.3966 -5.9641 28.1517
KP-2 CTRP2 -5.9415 -4.0911 -5.9528 28.0518
SW1990 CTRP2 -5.6725 -3.8413 -5.6872 26.2706
Panc 04.03 CTRP2 -5.53 -3.7336 -5.5456 25.3242
MIA PaCa-2 CTRP2 -5.2885 -4.6038 -5.2885 23.6629
AsPC-1 CTRP2 -5.2856 -3.3181 -5.319 23.7561
Panc 03.27 CTRP2; CTRP1 -5.2602 -4.3291 -5.2602 47.3253
PaTu 8988s CTRP2 -5.191 -2.3553 -5.3574 23.5843
DAN-G CTRP2 -4.9901 -3.981 -4.9909 21.6778
HuP-T3 CTRP2 -4.9021 2.1366 -6.6849 27.321
PK-45H CTRP2 -4.6036 -1.8468 -4.8361 19.9097
YAPC CTRP2 -4.4225 -3.7682 -4.4226 17.5492
QGP-1 CTRP2; CTRP1 -4.0838 -3.3157 -4.0838 41.8056
Panc 10.05 CTRP2; CTRP1 -4.0134 0.1554 -4.0449 41.6693
PaTu 8902 CTRP2; CTRP1 -3.9786 -1.2718 -3.9802 41.328
KP-4 CTRP2 -3.9363 -2.5131 -3.9816 14.4659
PK-59 CTRP2 -3.637 -2.5891 -3.6563 12.3856
TCC-Pan2 CTRP2 -3.2658 -1.9314 -3.3637 10.1887
BxPC-3 CTRP2 -3.1005 -1.8047 -3.2154 9.1508
Panc 08.13 CTRP2 -3.0541 -0.2956 -3.7206 11.2873
Capan-1 CTRP2 -2.9044 -0.6536 -3.4111 9.6731
HPAC CTRP2; CTRP1 -2.4884 -1.0335 -2.4885 34.5109
SU.86.86 CTRP2 -2.4616 -1.3037 -2.6942 5.3563
CFPAC-1 CTRP2; CTRP1 -2.0008 -1.0595 -2.0008 32.2809
SNU-213 CTRP2 -1.7282 -0.7871 -2.238 1.7904
KP-3 CTRP2; CTRP1 -1.6352 -0.0365 -1.6353 30.6095
HuP-T4 CTRP2; CTRP1 -1.4025 -0.1998 -1.4025 29.5453
SUIT-2 CTRP2; CTRP1 -1.3081 -0.6025 -1.3081 29.1138
HPAF-II CTRP2 0.089 5.2465 -3.8892 5.7922
Panc 05.04 CTRP2 0.1405 2.3133 -2.5394 0.8771
SNU-410 CTRP2 0.8279 2.7638 -2.419 0.2944
Capan-2 CTRP2; CTRP1 6.5938 20.0142 -1.1813 15.5103
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 -5.8486 -2.391 -6.0639 28.1263
HMCB CTRP2 -6.2167 -5.8769 -6.2167 29.8473
MeWo CTRP2 -6.1194 -5.629 -6.1194 29.1994
SK-MEL-2 CTRP2 -5.8534 -2.6907 -6.0096 27.9564
COLO 800 CTRP2 -5.2277 -4.4141 -5.2277 23.2581
WM266-4 CTRP2 -5.1579 -4.8073 -5.1579 22.7927
IGR-1 CTRP2 -4.997 -3.967 -4.9979 21.724
COLO 829 CTRP2 -4.4881 -2.4867 -4.5729 18.6192
CJM [Human melanoma] CTRP2 -4.2643 -3.805 -4.2643 16.8391
MDA-MB-435S CTRP2 -4.2546 -3.7759 -4.2546 16.4311
IGR-37 CTRP2 -4.2122 -2.6256 -4.2576 16.6457
A2058 CTRP2 -4.1126 -3.6561 -4.1126 15.8286
Hs 852.T CTRP2; CTRP1 -4.0189 -2.3783 -4.0189 41.5091
SK-MEL-24 CTRP2 -3.9199 -2.7363 -3.9383 14.6062
Mel JuSo CTRP2 -3.8059 -2.9763 -3.8095 13.4566
RVH-421 CTRP2 -3.722 -2.5707 -3.7452 13.3042
LOX-IMVI CTRP2 -3.6819 -2.3472 -3.7295 13.0638
A-375 CTRP2; CTRP1 -3.6672 -1.8652 -3.8179 13.0459
COLO 792 CTRP2 -3.2922 -1.7834 -3.4218 10.8142
WM115 CTRP2 -3.1753 -1.2433 -3.4646 10.6258
RPMI-7951 CTRP2 -3.1518 -2.5904 -3.1543 9.0995
IPC-298 CTRP2 -3.094 -2.0194 -3.1572 8.9236
WM1799 CTRP2 -3.019 -2.4995 -3.0215 8.2157
Hs 294T CTRP2 -2.9625 -1.7758 -3.064 8.5197
COLO 741 CTRP2; CTRP1 -2.9464 5.9306 -3.9302 38.4028
UACC-62 CTRP2 -2.7789 0.4191 -3.7713 10.8004
UACC-257 CTRP2 -2.7754 0.1213 -3.6284 10.2123
G-361 CTRP2; CTRP1 -2.7303 -1.6237 -2.7303 35.6167
Mel Ho CTRP2 -2.2366 -0.2783 -2.9418 5.7992
WM793 CTRP2 -2.0928 -1.2828 -2.3235 2.9285
A101D CTRP2 -1.8781 -1.2295 -2.1161 1.8891
SK-MEL-30 CTRP2 -1.8768 -1.0555 -2.2294 2.0455
SK-MEL-28 CTRP2; CTRP1 -1.6617 -0.5243 -2.3164 1.9997
SK-MEL-5 CTRP2; CTRP1 -1.5345 -0.3718 -2.296 1.7033
Hs 944.T CTRP2; CTRP1 -1.353 -0.5899 -1.353 29.3187
Hs 940.T CTRP2 -1.2754 7.686 -6.0695 16.7362
Hs 936.T CTRP2; CTRP1 -1.138 0.452 -1.1382 28.3362
K029AX CTRP2 -0.9881 3.322 -3.6727 6.797
Malme-3M CTRP2 0.3116 2.9656 -2.6802 1.3554
WT2-iPS CTRP2 0.3907 1.8975 -2.2275 0.2008
Hs 895.T CTRP2 0.437 3.8876 -3.0108 2.3388
Hs 839.T CTRP2 0.507 1.8167 -2.157 0.091
SK-MEL-1 CTRP2; CTRP1 0.5241 1.9341 -2.2394 0.1152
HT-144 CTRP2 0.5469 2.7259 -2.4727 0.6295
SK-MEL-31 CTRP2 0.6308 1.9398 -2.2039 0.068
Hs 688(A).T CTRP2 0.7785 2.2202 -2.1988 0.0935
SK-MEL-3 CTRP2 0.8651 2.1335 -2.1403 0.0422
WM88 CTRP2 1.1078 3.1617 -2.4069 0.2901
WM983B CTRP2 1.463 3.1954 -2.2903 0.09
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 -7.3545 -5.6932 -7.3554 37.4312
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-32 CTRP2 -11.232 -10.8165 -11.232 63.2633
SK-N-DZ CTRP2 -11.1905 -10.6358 -11.1905 62.9867
SK-N-FI CTRP2 -8.5576 -7.2856 -8.5576 45.4446
NH-6 CTRP2 -8.1574 -7.0959 -8.1574 42.778
Kelly CTRP2 -7.4007 -6.7914 -7.4007 37.3708
CHP-212 CTRP2 -7.117 -6.5281 -7.117 35.8461
SK-N-SH CTRP2 -6.8745 -5.3736 -6.8753 34.2331
SK-N-AS CTRP2 -5.1694 -2.04 -5.4047 23.6828
NB1 CTRP2 -5.1123 -4.5877 -5.1123 22.1396
CHP-126 CTRP2 -4.8731 -3.5768 -4.8793 20.5685
KP-N-SI9s CTRP2 -4.161 -3.5959 -4.161 15.8082
KP-N-YN CTRP2 -2.9972 14.3323 -10.8445 32.3174
SK-N-BE(2) CTRP2 0.8716 6.6049 -3.9863 5.4272
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 -5.2995 -1.2893 -5.7666 25.0173
SNU-869 CTRP2 -4.6511 -3.4913 -4.6553 19.43
SNU-478 CTRP2 -3.0263 -2.1336 -3.0629 8.3805
SNU-1196 CTRP2 -3.0184 -1.9374 -3.0928 8.4601
HuH-28 CTRP2 -2.3096 -0.5353 -2.8876 5.7463
SNU-308 CTRP2 -1.3882 0.4641 -2.5991 2.7204
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-673 CTRP2 -11.2091 -10.7596 -11.2091 63.111
SK-N-MC CTRP2 -11.1662 -10.8103 -11.1662 62.8249
MHH-ES-1 CTRP2 -7.3215 -6.1311 -7.3215 36.8436
TC71 CTRP2 -7.2383 -6.6458 -7.2383 36.6545
MG-63 CTRP2 -7.1867 -6.1988 -7.1868 36.3107
HOS CTRP2 -6.3103 -5.8259 -6.3103 30.4709
U2OS CTRP2; CTRP1 -5.1576 -3.2666 -5.1912 22.5543
CAL-78 CTRP2 -4.5968 -3.142 -4.6155 18.7714
SJSA-1 CTRP2 -4.0583 -2.959 -4.0689 15.1599
SW1353 CTRP2 -1.5211 0.1023 -2.5194 2.6058
Hs 888.T CTRP2 0.1032 2.3586 -2.5305 1.0533
Hs 822.T CTRP2 0.4292 7.0969 -4.5051 7.9893
SK-ES-1 CTRP2 0.4657 2.885 -2.5722 0.9308
SaOS-2 CTRP2 0.6431 2.5534 -2.3673 0.3634
G-292 clone A141B1 CTRP2 2.7039 13.7232 -6.1536 10.8562
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 72 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 CTRP2 -11.3537 -10.6427 -11.3537 64.0745
MDA-MB-453 CTRP2 -9.0696 -7.7512 -9.0696 48.856
Hs 578T CTRP2 -7.5167 -3.2675 -7.7023 39.0335
T-47D CTRP2 -7.1795 -4.805 -7.1934 36.3079
MDA-MB-468 CTRP2 -6.0355 -5.166 -6.0355 28.6403
HCC1143 CTRP2 -5.5443 -4.3923 -5.5451 25.0176
HCC38 CTRP2 -5.5314 -2.1447 -5.7741 26.1146
CAL-51 CTRP2 -5.1345 -3.2422 -5.1691 22.4038
AU565 CTRP2 -4.9377 -1.9891 -5.1646 22.1122
HMC-1-8 CTRP2 -4.24 -3.6276 -4.2401 16.3344
BT-474 CTRP2 -3.8027 -1.4491 -4.076 14.7319
CAL-85-1 CTRP2 -3.7288 -0.3351 -4.4065 15.7721
JIMT-1 CTRP2 -3.2996 -2.5998 -3.305 10.0928
HCC1806 CTRP2 -3.1755 -2.4019 -3.1888 9.2937
ZR-75-1 CTRP2 -3.1617 -1.3165 -3.4374 10.1493
CAL-120 CTRP2 -2.8786 -1.4242 -3.0936 8.046
UACC-812 CTRP2 -2.8513 1.1276 -4.1783 12.632
HCC1428 CTRP2 -2.8324 4.4991 -5.8091 19.0162
EFM-192A CTRP2 -2.801 -0.7634 -3.2569 8.7932
HCC202 CTRP2 -2.7786 3.2342 -5.1363 16.3262
HCC1419 CTRP2 -2.6526 1.9639 -4.3966 13.0661
HDQ-P1 CTRP2 -1.6759 0.5923 -2.8846 4.4063
HCC1954 CTRP2 -1.6246 2.8598 -3.9757 8.8815
HCC1937 CTRP2 -1.5613 18.0669 -11.5257 30.5579
MDA-MB-231 CTRP2 -1.3134 0.719 -2.6697 2.8936
CAMA-1 CTRP2 -1.2599 1.0295 -2.7829 3.2751
BT-20 CTRP2 -0.9366 3.2211 -3.5847 6.3494
ZR-75-30 CTRP2 -0.4649 4.2171 -3.732 6.2194
MDA-MB-361 CTRP2 -0.2758 8.5575 -12.6776 4.2838
Hs 578Bst CTRP2 0.0783 1.9402 -2.3727 0.6267
KPL-1 CTRP2 0.208 2.0769 -2.4153 0.5186
MCF-7 CTRP2; CTRP1 0.4084 4.1789 -3.199 2.8048
HCC1500 CTRP2 0.8211 4.1856 -2.936 1.7588
SK-BR-3 CTRP2 0.8778 2.5714 -2.2841 0.1699
MDA-MB-415 CTRP2 1.0186 2.5594 -2.2299 0.0909
BT-549 CTRP2 1.1509 4.047 -2.7223 0.9308
HCC1395 CTRP2 1.3138 3.2086 -2.3954 0.1556
MDA-MB-157 CTRP2 3.9273 29.2612 -12.8065 24.8448
BT 271 CTRP2 -8.1559 -5.2455 -8.1765 42.8234
BT164 CTRP2 -8.1031 -6.3184 -8.1038 42.4184
BT 286 CTRP2 -7.8938 -5.8647 -7.8962 41.0291
BT 145 CTRP2 -7.364 -6.7051 -7.364 37.4919
BT 330 CTRP2 -7.2313 -4.6233 -7.2542 36.6816
BT 228 CTRP2 -7.1524 -6.7425 -7.1524 36.082
BT 428 CTRP2 -7.0888 -1.5472 -7.6305 37.1981
BT 245 CTRP2 -6.9476 -5.4691 -6.9482 34.7191
BT 179 CTRP2 -6.9444 -6.1603 -6.9444 34.6959
BT 172 CTRP2 -6.7291 -4.9205 -6.7329 33.274
BT147 CTRP2 -6.5302 -4.9998 -6.5317 31.9412
BT 416 CTRP2 -6.3754 -5.5463 -6.3754 30.9049
BT 504 CTRP2 -6.1645 -5.0654 -6.1647 29.5005
BT 232 CTRP2 -6.1042 -5.5499 -6.1042 29.0976
BT 328 CTRP2 -5.8733 -3.8841 -5.8919 27.6217
BT 131 CTRP2 -5.8571 -4.0057 -5.8697 27.4936
BT 216 CTRP2 -5.7597 -3.602 -5.7918 26.9102
BT 482 CTRP2 -5.6875 -3.1184 -5.7646 26.5823
BT 422 CTRP2 -5.3764 -2.3033 -5.5697 24.9124
BT 440 CTRP2 -5.2729 -2.677 -5.3858 23.9436
BT 187 CTRP2 -4.5692 -1.782 -4.8157 19.731
BT 159 CTRP2 -4.5524 -2.2432 -4.6876 19.2233
BT 248 CTRP2 -4.2292 -0.4328 -4.898 19.0395
BT 224 CTRP2 -4.0042 -0.0464 -4.8144 18.096
BT 112 CTRP2 -3.6663 -0.3018 -4.3544 15.4007
BT 333 CTRP2 -3.291 -0.4618 -3.8948 12.5993
BT 231 CTRP2 -3.0849 3.315 -5.4586 18.2797
BT 340 CTRP2 -3.0242 1.0755 -4.3206 13.6229
BT 320 CTRP2 -0.9213 2.445 -3.1933 4.7154
BT 139 CTRP2 -0.0938 2.9712 -2.9037 2.495
BT 239 CTRP2 -0.0145 2.4567 -2.632 1.4667
BT 498 CTRP2 0.3059 3.72 -3.0097 2.4624
BT 359 CTRP2 2.4912 17.0884 -7.9014 16.4191
BT 444 CTRP2 4.6706 25.091 -10.2596 19.292
⏷ Show the Full List of 72 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 -3.1648 -2.7602 -3.165 9.1781
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AM-38 CTRP2 -14.4471 2.5576 -16.993 64.9987
D283 Med CTRP2 -11.2069 -10.7276 -11.2069 63.0962
SF539 CTRP2 -9.2285 -8.7646 -9.2285 49.9146
42-MG-BA CTRP2 -9.2259 -8.7863 -9.2259 49.8975
A-172 CTRP2 -7.272 -6.365 -7.272 36.8787
U-118MG CTRP2 -6.919 -5.7431 -6.9191 34.5272
SF268 CTRP2 -6.1821 -5.3768 -6.1821 29.6172
8-MG-BA CTRP2 -6.0676 -5.0128 -6.0677 28.8543
CCF-STTG1 CTRP2 -6.023 -5.4542 -6.023 28.5568
U-251MG CTRP2 -5.9882 -4.8101 -5.9886 28.3262
Becker CTRP2 -5.5034 -4.6631 -5.5034 25.0951
GMS-10 CTRP2 -5.1663 -3.5343 -5.1809 22.8977
TM-31 CTRP2 -5.0357 -4.4013 -5.0357 21.9787
SNU-738 CTRP2 -4.9055 -4.0704 -4.9057 20.764
YKG-1 CTRP2 -4.8249 -3.8673 -4.8256 20.5767
SNB-75 CTRP2 -4.5178 -1.6023 -4.8096 19.5525
T98G CTRP2 -4.4026 -3.0711 -4.4173 17.8098
Hs 683 CTRP2 -4.3053 -2.1724 -4.4341 17.5556
GB-1 CTRP2 -4.2608 -3.7939 -4.2608 16.4727
KNS-60 CTRP2 -4.2187 -3.8113 -4.2187 16.1922
KNS-42 CTRP2 -4.1627 -2.7255 -4.194 16.2674
DK-MG CTRP2 -3.8123 -1.6545 -4.0249 14.5741
KG-1-C CTRP2 -3.7137 -1.0239 -4.1238 14.6505
SF295 CTRP2; CTRP1 -3.5905 -2.5593 -3.5905 39.55
GOS-3 CTRP2 -3.5203 -0.0517 -4.3073 14.8249
M059K CTRP2 -3.4961 -0.461 -4.1101 13.9911
YH-13 CTRP2 -3.4598 -1.3949 -3.7206 12.4077
SF126 CTRP2 -3.2673 -2.832 -3.2675 9.8607
GaMG CTRP2; CTRP1 -3.1128 -2.338 -3.1128 37.366
LN-229 CTRP2; CTRP1 -3.1077 -1.9811 -3.1802 9.0473
CAS-1 CTRP2 -2.9804 -1.519 -3.171 8.63
SNU-1105 CTRP2 -2.9279 -1.7863 -3.032 7.9648
Daoy CTRP2 -2.7915 -1.56 -2.9524 7.2671
SNU-201 CTRP2 -2.1964 2.3191 -4.1897 10.9039
KALS-1 CTRP2 -2.1547 -0.6587 -2.6802 4.533
LN-18 CTRP2 -1.912 -0.5556 -2.5091 3.2893
SNU-466 CTRP2 -1.7175 0.1298 -2.6874 3.656
SW1088 CTRP2 -1.4017 1.1008 -2.9229 4.0833
SW1783 CTRP2 0.0956 5.6727 -4.0483 6.6739
KNS-81 CTRP2 0.2286 1.8304 -2.3138 0.2968
SNU-489 CTRP2 0.3803 8.3102 -5.1624 10.3028
SNU-626 CTRP2 0.5213 2.0322 -2.2744 0.157
DBTRG-05MG CTRP2 0.6487 2.4054 -2.3588 0.2474
U-87MG ATCC CTRP2 0.8135 2.1138 -2.1997 0.0484
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2; CTRP1 -8.1828 -6.878 -8.1828 41.9678
JHUEM-1 CTRP2 -6.868 -5.9077 -6.868 34.1868
AN3-CA CTRP2 -6.8324 -5.6775 -6.8324 33.9499
EN CTRP2 -6.7873 -5.6734 -6.7873 33.6491
MFE-319 CTRP2; CTRP1 -6.1625 -5.5687 -6.1625 51.4634
ESS-1 CTRP2 -5.9981 -4.6975 -5.999 28.3942
JHUEM-3 CTRP2 -5.621 -3.0702 -5.7001 26.1459
RL95-2 CTRP2 -5.1772 -4.6914 -5.1772 22.5716
JHUEM-7 CTRP2 -5.0338 -3.7831 -5.0373 21.9778
HEC-59 CTRP2; CTRP1 -4.3424 -2.9223 -4.3424 42.9882
HEC-50B CTRP2 -3.6553 -2.1698 -3.7354 12.7168
KLE CTRP2; CTRP1 -3.3361 -1.5156 -3.3361 38.3869
HEC-265 CTRP1 -3.235 0.1262 -3.2485 92.2905
HEC-108 CTRP2; CTRP1 -3.0926 -2.5754 -3.0926 37.2733
HEC-1-B CTRP2 -2.9851 -0.984 -3.3759 9.4208
HEC-6 CTRP2; CTRP1 -2.44 -1.9636 -2.44 34.2895
EFE-184 CTRP2 -0.2715 2.6338 -2.8976 2.431
HEC-1-A CTRP2 0.3933 3.2388 -2.7539 1.5227
HEC-151 CTRP2; CTRP1 0.5515 2.3002 -2.3584 0.2737
MFE-296 CTRP2 0.5658 3.8856 -2.9404 1.9836
HEC-251 CTRP2; CTRP1 1.4683 7.3586 0.3387 19.2575
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 -3.7265 -3.1018 -3.7265 40.1718
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UO-31 CTRP2 -6.1522 -5.4258 -6.1522 29.4177
KMRC-3 CTRP2 -5.4512 2.225 -7.286 30.7525
786-O CTRP2 -5.238 -4.3365 -5.2381 23.3271
RCC10RGB CTRP2; CTRP1 -4.4867 -0.2051 -5.2608 21.1301
CAL-54 CTRP2 -3.7658 -0.9223 -4.2169 15.1503
KMRC-1 CTRP2 -3.5999 1.8282 -5.2381 18.6781
ACHN CTRP2 -3.3925 -1.2847 -3.6847 12.078
769-P CTRP2 -3.192 -2.1226 -3.2433 9.5341
Caki-1 CTRP2 -3.0774 1.2049 -4.4336 14.2081
BFTC-909 CTRP2 -2.8934 -1.5704 -3.0596 7.9625
KMRC-2 CTRP2 -2.8275 0.2762 -3.7519 10.8403
VMRC-RCZ CTRP2 -2.1504 0.9537 -3.4407 8.0021
VMRC-RCW CTRP2; CTRP1 -1.3343 -0.1152 -1.3344 29.2337
KMRC-20 CTRP2 -0.9587 0.9528 -2.5425 1.8917
A-498 CTRP2 -0.855 0.9397 -2.4313 1.5915
TUHR14TKB CTRP2 -0.7434 8.6257 -6.1153 15.9164
TUHR4TKB CTRP2 0.1735 2.6058 -2.6436 1.1588
TUHR10TKB CTRP2 0.5323 15.3055 -8.4849 20.695
SNU-1272 CTRP2 0.6689 2.2464 -2.2952 0.1539
OS-RC-2 CTRP2 0.9636 2.485 -2.2723 0.0861
Caki-2 CTRP2 1.2312 2.9928 -2.3025 0.1302
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 320 CTRP2; CTRP1 -8.3649 -4.9013 -8.4112 44.2644
NCI-H716 CTRP2 -7.4956 -6.4607 -7.4956 38.3686
HCT 8 CTRP2; CTRP1 -7.2476 -5.3271 -7.2507 36.7264
SNU-1033 CTRP2 -7.1062 -4.5094 -7.1311 35.855
HCT 15 CTRP2 -6.8993 -5.2179 -6.9011 34.4016
C2BBe1 CTRP2; CTRP1 -6.8315 -4.33 -6.8315 54.5306
SNU-C4 CTRP2; CTRP1 -6.6926 -5.8583 -6.6926 33.0186
SNU-C1 CTRP2 -6.2345 -4.6321 -6.2375 29.9761
HCC-56 CTRP2 -6.0949 -5.55 -6.0949 29.0358
T84 CTRP2 -5.84 -3.5452 -5.8804 27.4733
RCM-1 [Human ESC] CTRP2; CTRP1 -5.6766 -3.7361 -5.6968 26.3164
LS1034 CTRP2 -5.661 -3.5694 -5.6914 26.2468
CL-34 CTRP1 -5.5759 -2.6719 -5.7351 51.6417
NCI-H747 CTRP2 -5.5686 0.6518 -6.7478 29.5034
COLO201 CTRP2 -5.2904 -4.5663 -5.2904 23.325
SNU-407 CTRP2 -5.0842 -3.849 -5.0874 21.9635
HT115 CTRP2; CTRP1 -5.0469 -3.8116 -5.0503 21.7158
SW620 CTRP2; CTRP1 -5.0197 -3.3655 -5.0399 21.5911
SW1417 CTRP2 -4.3399 -1.5214 -4.6393 18.3978
HT-55 CTRP2; CTRP1 -3.9025 -2.5103 -3.9459 14.2344
SW48 CTRP2; CTRP1 -3.898 -2.7301 -3.898 40.9562
SW480 CTRP1 -3.8863 0.8701 -5.1769 35.4739
LS180 CTRP2; CTRP1 -3.7975 -2.2911 -3.8668 13.6252
NCI-H508 CTRP2; CTRP1 -3.3236 -2.4587 -3.3391 10.2865
LS513 CTRP2; CTRP1 -3.2349 -2.4167 -3.2349 37.9243
RKO CTRP2; CTRP1 -3.1745 -1.5994 -3.356 9.8845
LS411N CTRP2; CTRP1 -3.1326 -2.6145 -3.1326 37.4564
SW403 CTRP1 -3.1185 18.2143 -9.1514 61.6963
OUMS-23 CTRP2 -3.009 -1.8558 -3.1022 8.4648
SNU-1040 CTRP1 -2.41 -1.9178 -2.4599 7.0415
CL-11 CTRP2 -2.3264 -0.7863 -2.7855 5.3713
MDST8 CTRP2; CTRP1 -1.6951 -0.1006 -2.5542 3.0555
LS123 CTRP2; CTRP1 -1.6329 -0.0589 -2.5254 2.823
SK-CO-1 CTRP2; CTRP1 -1.4944 -0.2659 -1.4944 29.9656
SNU-C2A CTRP2; CTRP1 -1.4499 -0.1618 -1.4499 29.7619
GP2d CTRP2; CTRP1 -1.4026 -0.6149 -1.4026 29.6335
COLO205 CTRP2; CTRP1 -1.3025 -0.8684 -1.3025 29.0881
DLD-1 CTRP2; CTRP1 -1.2343 -0.8484 -1.2343 28.7763
LoVo CTRP2; CTRP1 -0.7403 2.0363 -2.9116 3.0502
SNU-C5 CTRP2; CTRP1 0.0177 10.9145 -6.7028 16.3295
SW948 CTRP2; CTRP1 0.068 5.6611 -4.0613 6.7642
CL-40 CTRP1 0.1778 2.2193 -2.6337 1.2883
HT-29 CTRP2; CTRP1 0.4743 1.9192 -2.2522 0.1386
SNU-175 CTRP1 0.4852 2.3762 -2.5652 0.7102
COLO 678 CTRP2; CTRP1 0.5539 3.1982 -2.6576 1.1139
SNU-81 CTRP2; CTRP1 0.6007 2.511 -2.416 0.3603
CCK-81 CTRP2 0.6078 2.812 -2.5263 0.5876
HCT 116 CTRP2; CTRP1 0.8024 2.2341 -2.2436 0.0809
KM12 CTRP2; CTRP1 0.8209 2.7226 -2.4068 0.2766
SNU-503 CTRP2 0.8397 2.5129 -2.2776 0.1693
CW-2 CTRP2; CTRP1 1.6635 3.4723 -2.3627 0.0823
SNU-61 CTRP2; CTRP1 3.1772 13.0962 -5.6103 8.281
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 CTRP2 -7.2153 -6.8482 -7.2153 36.5013
SNU-449 CTRP2; CTRP1 -7.2006 -5.8642 -7.2006 56.2245
HLF CTRP2 -7.1523 -6.5595 -7.1523 36.0812
SNU-423 CTRP2 -6.1595 -5.1504 -6.1596 29.4669
JHH-4 CTRP2 -5.938 -4.847 -5.9382 27.9914
HuH-6 CTRP2 -5.9348 -3.104 -6.0338 27.9482
SNU-182 CTRP2 -5.4241 -3.2713 -5.4708 24.3721
SNU-761 CTRP2 -5.0616 -4.3997 -5.0616 21.8025
SK-HEP-1 CTRP2 -4.971 -3.9302 -4.972 21.5508
SNU-475 CTRP2 -4.0358 -1.1885 -4.4144 16.6695
PLC/PRF/5 CTRP2 -4.0018 -0.8506 -4.4969 16.88
Li-7 CTRP2 -3.3669 -1.7493 -3.5214 11.0642
Hep-G2 CTRP2; CTRP1 -3.0062 0.6122 -4.1087 12.3916
Hep 3B2.1-7 CTRP2 -2.544 0.8168 -3.7627 9.8881
JHH-6 CTRP2; CTRP1 -2.4083 -1.7601 -2.4083 34.246
HuH-1 CTRP2 -1.5311 1.5144 -3.1944 5.7407
JHH-2 CTRP2 -0.0382 6.5743 -4.5761 8.9502
JHH-5 CTRP2 0.6066 2.4091 -2.3288 0.3053
SNU-886 CTRP2 0.8353 2.9354 -2.4787 0.3971
SNU-387 CTRP2 0.8402 2.7418 -2.3586 0.2863
SNU-878 CTRP2 0.9796 2.637 -2.3183 0.1268
SNU-398 CTRP2; CTRP1 2.0198 15.8278 -7.6581 16.1768
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 158 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1092 CTRP2 -11.0075 -6.125 -11.075 60.915
DMS 114 CTRP2 -9.3795 -8.6747 -9.3795 50.9207
NCI-H2081 CTRP2; CTRP1 -8.3193 -6.0771 -8.3225 43.8655
COR-L51 CTRP2; CTRP1 -8.3091 -7.7634 -8.3091 43.7888
NCI-H520 CTRP2 -8.2702 -4.5839 -8.3372 43.4985
NCI-H810 CTRP2; CTRP1 -8.2251 -7.6042 -8.2251 60.9227
NCI-H522 CTRP2; CTRP1 -8.0824 -6.3672 -8.0824 60.2684
DV-90 CTRP2; CTRP1 -7.8513 -4.7947 -7.8515 59.1984
NCI-H146 CTRP2 -7.6139 -6.3135 -7.614 39.1572
NCI-H1105 CTRP2; CTRP1 -7.4896 -5.7231 -7.4908 38.3324
Calu-3 CTRP2; CTRP1 -7.3269 1.8309 -7.7333 55.7229
NCI-H1930 CTRP1 -7.2999 -6.4306 -7.2999 90.6886
CAL-12T CTRP2; CTRP1 -7.286 -5.3078 -7.29 36.6203
SCLC-21H CTRP1 -7.267 -6.5986 -7.267 76.0344
NCI-H211 CTRP2 -7.2451 -6.4734 -7.2451 36.3352
ChaGo-K-1 CTRP2; CTRP1 -7.1793 -5.802 -7.1793 56.1267
NCI-H841 CTRP2; CTRP1 -7.1264 -6.1488 -7.1264 35.9086
NCI-H1568 CTRP2; CTRP1 -7.1147 -5.9059 -7.1147 55.8305
NCI-H1876 CTRP1 -7.1096 -2.8287 -7.3667 66.5311
NCI-H23 CTRP2; CTRP1 -6.9605 -5.7841 -6.9605 55.1231
NCI-H1693 CTRP2 -6.9561 -5.6047 -6.9564 34.7751
NCI-H1341 CTRP2 -6.951 -6.0391 -6.951 34.7398
NCI-H322 CTRP2 -6.9362 -5.5712 -6.9365 34.6424
DMS 53 CTRP2 -6.8605 -5.3107 -6.8615 34.1403
NCI-H2141 CTRP2; CTRP1 -6.8498 -1.9053 -7.2717 35.3538
NCI-H2030 CTRP2; CTRP1 -6.815 -6.009 -6.815 32.7673
COR-L95 CTRP2 -6.7419 -5.0839 -6.7439 33.3537
NCI-H1155 CTRP2 -6.2774 -5.7567 -6.2774 29.8945
DMS 273 CTRP2; CTRP1 -6.141 -5.5103 -6.141 51.3647
NCI-H661 CTRP2; CTRP1 -6.1396 -5.0477 -6.1396 51.2059
HCC1438 CTRP2 -6.0718 -5.6047 -6.0718 28.8818
LK2 CTRP2 -5.9954 -5.4409 -5.9954 28.373
COLO 668 CTRP2; CTRP1 -5.9669 -4.2932 -5.9669 50.5665
NCI-H2196 CTRP2 -5.8025 -4.4597 -5.804 27.0928
RERF-LC-KJ CTRP1 -5.7948 -4.0551 -5.7948 79.5737
VMRC-LCD CTRP2; CTRP1 -5.7563 -3.8069 -5.7563 49.6006
NCI-H596 CTRP1 -5.5436 -4.8588 -5.5436 51.4314
HOP-62 CTRP2 -5.4487 -3.3474 -5.4874 24.8605
NCI-H838 CTRP2 -5.3418 -4.6867 -5.3418 24.0184
SHP-77 CTRP2; CTRP1 -5.2655 -4.7451 -5.2655 47.2092
NCI-H446 CTRP2 -5.187 -4.5326 -5.187 22.6369
NCI-H1703 CTRP2 -5.1175 -4.4754 -5.1175 22.5236
Lu-65 CTRP2; CTRP1 -5.113 -4.2577 -5.113 46.6501
NCI-H1836 CTRP1 -5.0578 0.1104 -6.0613 46.5255
RERF-LC-Ad2 CTRP2 -5.0413 -1.223 -5.4955 23.6141
RERF-LC-MS CTRP2 -5.0362 -3.1971 -5.068 22.089
NCI-H526 CTRP2 -4.8923 -3.9783 -4.8927 20.6769
LC-1/sq-SF CTRP2; CTRP1 -4.8393 -2.952 -4.8393 45.3951
NCI-H1963 CTRP1 -4.8192 32.581 -21.657 49.0865
NCI-H1184 CTRP2 -4.5178 -2.9886 -4.5447 18.2731
RERF-LC-A1 CTRP2 -4.4815 -3.6324 -4.4822 17.9439
SK-MES-1 CTRP2 -4.409 -0.999 -4.8834 19.5001
HCC366 CTRP2 -4.3611 -3.5353 -4.3619 17.1425
NCI-H1048 CTRP1 -4.3433 -2.4633 -4.3434 99.2836
NCI-H1437 CTRP1 -4.2751 0.9525 -4.3674 89.8422
NCI-H1651 CTRP2 -4.2626 -2.0101 -4.4238 17.3857
NCI-H1435 CTRP2; CTRP1 -4.2129 -1.9192 -4.2132 42.3966
NCI-H889 CTRP2 -4.1256 -3.1745 -4.1295 15.5855
NCI-H1339 CTRP2 -4.1148 -2.6262 -4.1541 15.9759
NCI-H2106 CTRP2 -4.0991 -2.2779 -4.1951 15.7247
DMS 79 CTRP2 -4.0174 -0.7586 -4.5625 16.8304
NCI-H82 CTRP1 -4.0035 -2.2633 -4.0035 99.1922
HCC33 CTRP1 -3.9924 -2.2273 -3.9924 99.1397
NCI-H1915 CTRP2; CTRP1 -3.9907 -2.4208 -3.9907 41.5032
NCI-H1581 CTRP2 -3.8797 -2.0996 -3.9935 14.3278
NCI-H1355 CTRP2; CTRP1 -3.7474 -2.2758 -3.7474 40.2676
SW1271 CTRP2 -3.7436 -2.8167 -3.7516 13.0567
HOP-92 CTRP2 -3.6826 0.5461 -4.735 16.9282
MOR/CPR CTRP2 -3.6256 -2.8375 -3.6298 12.259
HCC1359 CTRP1 -3.4363 -2.6623 -3.4464 21.3999
HCC827 CTRP2; CTRP1 -3.3424 -2.5336 -3.3585 9.4649
LXF 289 CTRP2; CTRP1 -3.3261 -2.4559 -3.3261 38.341
NCI-H2286 CTRP2; CTRP1 -3.2856 -1.8492 -3.2856 38.1558
NCI-H1573 CTRP1 -3.2754 2.544 -3.4938 83.708
Calu-6 CTRP2; CTRP1 -3.1622 -2.2295 -3.1622 37.5917
NCI-H1869 CTRP2 -3.1107 -1.9833 -3.1768 9.3799
HCC78 CTRP2; CTRP1 -3.0661 -2.0371 -3.0661 37.1524
NCI-H2405 CTRP2; CTRP1 -3.0613 -1.5361 -3.0613 37.1302
NCI-H292 CTRP2 -3.06 -2.2383 -3.084 8.5612
NCI-H2087 CTRP2 -3.0396 -1.7063 -3.1767 8.8265
HCC1588 CTRP2 -3.0387 -2.0792 -3.0857 8.4992
NCI-H1975 CTRP2; CTRP1 -3.0348 -1.1203 -3.035 37.0097
NCI-H1650 CTRP2 -2.8062 -0.1646 -3.5496 9.6413
T3M-10 CTRP2; CTRP1 -2.6354 0.7281 -3.7799 10.4945
NCI-H1781 CTRP1 -2.5671 -1.6856 -2.7085 10.0079
A-549 CTRP2; CTRP1 -2.5651 -1.4562 -2.5651 34.8612
HCC2935 CTRP2; CTRP1 -2.5546 -0.8844 -2.95 6.9342
NCI-H1299 CTRP2; CTRP1 -2.5538 -1.1735 -2.5538 34.8096
KNS-62 CTRP2; CTRP1 -2.5233 -1.7236 -2.5233 34.7731
LCLC-97TM1 CTRP2; CTRP1 -2.3703 -0.7637 -2.3704 33.9709
HCC2108 CTRP2; CTRP1 -2.3513 0.2127 -3.3778 6.9318
LCLC-103H CTRP2; CTRP1 -2.2823 -1.8282 -2.2823 33.5681
COR-L23 CTRP1 -2.2709 3.748 -5.0664 26.2507
NCI-H647 CTRP2 -2.2225 -0.5825 -2.756 5.3233
HCC95 CTRP2 -2.0257 -0.639 -2.5697 3.785
NCI-H1373 CTRP2; CTRP1 -2.018 -0.6505 -2.018 32.3596
HCC2279 CTRP2 -1.9007 -0.0134 -2.7695 4.3576
SBC-5 CTRP2 -1.8256 -0.2455 -2.5894 3.4515
EPLC-272H CTRP2; CTRP1 -1.8048 0.1778 -1.8056 31.3866
NCI-H1734 CTRP2 -1.6909 0.0406 -2.6212 3.3291
COR-L279 CTRP2; CTRP1 -1.4576 -0.8669 -1.4576 29.8858
NCI-H524 CTRP2 -1.4324 0.9617 -2.8774 3.9455
HCC44 CTRP2; CTRP1 -1.4198 -0.5838 -1.4198 29.6242
NCI-H1792 CTRP2; CTRP1 -1.4152 0.0988 -1.4153 29.6035
NCI-H2009 CTRP2; CTRP1 -1.3907 -0.3254 -1.3907 29.4913
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 -1.3883 -0.5248 -1.3883 29.4801
COR-L88 CTRP2; CTRP1 -1.3564 4.6117 -1.8255 30.5008
NCI-H2170 CTRP2 -1.3394 2.2226 -3.3959 6.2425
Lu-99 CTRP2; CTRP1 -1.3378 -0.3766 -1.3378 29.2494
NCI-H441 CTRP2; CTRP1 -1.274 1.007 -2.7821 3.2939
NCI-H2029 CTRP2; CTRP1 -1.2361 6.1307 -2.131 30.9086
COR-L105 CTRP2 -1.2139 4.0389 -4.2014 9.3692
NCI-H1793 CTRP2; CTRP1 -1.1748 0.6451 -1.1757 28.591
NCI-H1395 CTRP2 -1.099 1.5079 -2.8634 3.6365
EBC-1 CTRP2; CTRP1 -1.0735 2.6861 -1.166 28.2544
NCI-H1755 CTRP2; CTRP1 -0.8925 1.2349 -2.6325 2.1564
NCI-H2073 CTRP1 -0.8792 2.1864 -3.203 7.5686
SK-LU-1 CTRP2; CTRP1 -0.7496 1.6499 -2.7361 2.3788
NCI-H358 CTRP2; CTRP1 -0.5484 2.6337 -0.6075 25.7762
NCI-H2023 CTRP2; CTRP1 -0.3196 1.7728 -2.5429 1.2314
NCI-H727 CTRP2; CTRP1 -0.2984 4.5127 -0.6481 25.3226
Sq-1 CTRP2; CTRP1 0.0088 1.593 -2.3149 0.3825
NCI-H2172 CTRP2; CTRP1 0.0746 1.9917 -2.4409 0.6506
DMS 454 CTRP2 0.2382 3.5799 -2.9857 2.445
NCI-H1666 CTRP2; CTRP1 0.2679 5.2719 -0.2294 23.1005
NCI-H196 CTRP2 0.3443 3.4701 -2.9228 1.9115
NCI-H226 CTRP2 0.3779 2.1216 -2.3615 0.3349
NCI-H1944 CTRP2; CTRP1 0.3846 7.7797 -0.9773 24.7791
HCC4006 CTRP2; CTRP1 0.4153 2.4325 -2.4163 0.5603
SW1573 CTRP2 0.475 3.1584 -2.7247 1.1857
EKVX CTRP2 0.5212 4.1552 -3.0821 2.5053
NCI-H2085 CTRP2 0.527 20.9023 -11.2648 26.7127
NCI-H1563 CTRP2 0.5652 3.0514 -2.5929 0.9263
NCI-H2110 CTRP2; CTRP1 0.6162 3.0393 -2.5648 0.8221
IA-LM CTRP2 0.69 2.2767 -2.2499 0.1641
LUDLU-1 CTRP2 0.7113 2.3173 -2.2563 0.168
HCC1833 CTRP2; CTRP1 0.7264 3.2413 -2.6413 0.8044
LOU-NH91 CTRP2 0.7396 4.3203 -3.0799 2.0882
NCI-H3255 CTRP1 0.7618 2.6735 -2.5657 0.5426
NCI-H2444 CTRP2 0.7772 2.1763 -2.2329 0.075
NCI-H460 CTRP2; CTRP1 0.7867 1.9127 -2.1428 0.0225
NCI-H1694 CTRP2; CTRP1 0.7878 2.3416 -2.237 0.1308
NCI-H2122 CTRP2; CTRP1 0.8458 2.2336 -2.2286 0.0647
HCC1171 CTRP2 0.852 3.6316 -2.739 0.9863
BEN CTRP2; CTRP1 0.8543 5.6379 0.3 20.5706
HCC1195 CTRP2; CTRP1 0.9017 2.3154 -2.2368 0.0652
NCI-H2228 CTRP2 0.9109 3.1075 -2.5119 0.4338
NCI-H2126 CTRP2; CTRP1 0.9189 6.7593 -0.0157 21.2387
NCI-H2342 CTRP2; CTRP1 0.9432 3.5731 -2.6287 0.8074
NCI-H1838 CTRP2 1.0252 23.5514 -12.1948 27.5442
HCC15 CTRP2; CTRP1 1.0779 4.4483 -2.9633 1.4675
Calu-1 CTRP2 1.1599 2.7325 -2.2393 0.0826
NCI-H2291 CTRP2 1.1996 3.3804 -2.498 0.3184
COLO 699 CTRP2; CTRP1 1.3629 2.9139 -2.2792 0.054
PC-14 CTRP2 1.5265 3.1032 -2.2868 0.047
NCI-H1623 CTRP2 1.5743 3.8658 -2.4814 0.2845
NCI-H650 CTRP2; CTRP1 2.4588 6.7129 1.6454 13.9421
Hs 888.Lu CTRP2 -0.2468 4.9397 -3.9298 6.6933
⏷ Show the Full List of 158 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 -7.5757 -4.8626 -7.5974 38.97
TE 441.T CTRP2 -10.8441 -9.6475 -10.8441 60.6789
TTC-709 CTRP2 -9.5284 -8.322 -9.5284 51.9126
BT-16 CTRP2 -9.0042 -8.425 -9.0042 48.4198
TE 617.T CTRP2 -8.1233 -6.6949 -8.1234 42.5512
A-204 CTRP2 -7.6928 -5.8147 -7.6944 39.6875
G-402 CTRP2 -7.4097 -6.0472 -7.4098 37.7965
RD CTRP2 -7.0972 -5.991 -7.0973 35.7144
KYM-1 CTRP2 -7.0358 -5.9893 -7.0358 35.305
G-401 CTRP2; CTRP1 -6.8674 -5.9225 -6.8674 54.6964
Tm87-16 CTRP2 -6.6732 -4.626 -6.6824 32.9196
Rh41 CTRP2 -6.5491 -5.7631 -6.5491 31.7025
MES-SA CTRP2 -6.4308 -5.4784 -6.4309 31.2744
SK-UT-1 CTRP2 -6.2939 -4.8132 -6.2954 30.3669
BT-12 CTRP2 -5.8622 -5.3828 -5.8622 27.4854
GCT CTRP2 -5.5977 -4.6464 -5.5978 25.7238
HT-1080 CTRP2; CTRP1 -5.4127 -4.5294 -5.4128 24.4909
Rh18 CTRP2 -4.8735 -3.6537 -4.8777 20.5644
SK-LMS-1 CTRP2 -4.7451 -3.5891 -4.7486 20.0542
Hs 729.T CTRP2 -3.1555 -1.3339 -3.4113 10.3692
RKN CTRP2; CTRP1 0.1084 2.1978 -2.5078 0.8094
SW982 CTRP2 0.377 1.803 -2.1992 0.1633
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -7.482 -5.0145 -7.4954 38.3205
JHOS-4 CTRP1 -9.7342 -4.2244 -9.7479 91.1186
A2780 CTRP2; CTRP1 -9.5837 -8.6546 -9.5837 51.9002
COV434 CTRP2; CTRP1 -8.3335 -4.0396 -8.4628 44.2146
OVCAR-5 CTRP2 -7.9341 -5.9044 -7.9363 41.2972
OVKATE CTRP1 -7.5062 -6.8044 -7.5062 79.4183
OVCAR-8 CTRP2; CTRP1 -7.0332 -5.3651 -7.0347 34.9295
EFO-27 CTRP2; CTRP1 -6.5677 -4.479 -6.5794 32.2251
TOV-21G CTRP2 -6.1966 -4.6961 -6.1986 29.7204
OC 314 CTRP2 -6.1759 -5.7716 -6.1759 29.5754
OAW42 CTRP2; CTRP1 -5.9426 -5.009 -5.9426 28.0213
OVMANA CTRP1 -5.9401 -4.337 -5.9401 80.6698
EFO-21 CTRP2; CTRP1 -5.7109 -3.4381 -5.7109 49.3921
OVK18 CTRP2; CTRP1 -5.5764 -4.4293 -5.5771 25.2311
OV7 CTRP2; CTRP1 -5.4508 -3.8081 -5.4611 24.779
COV318 CTRP1 -5.3323 16.4241 -10.5881 58.6306
ONCO-DG-1 CTRP2 -5.2626 -4.7665 -5.2626 23.1403
DOV13 CTRP2 -5.2559 -4.6797 -5.2559 23.0958
COV644 CTRP2; CTRP1 -5.0186 -2.8903 -5.0819 22.0793
JHOS-2 CTRP2 -4.9847 -2.3399 -5.1367 22.1609
OVISE CTRP2 -4.8999 -3.9574 -4.9005 20.7278
HEY A8 CTRP2; CTRP1 -4.348 -3.85 -4.348 43.0139
TOV-112D CTRP2 -4.0291 2.1997 -5.8353 22.02
RMUG-S CTRP1 -3.9464 7.7503 -8.5462 43.2523
OAW28 CTRP2 -3.8237 0.5845 -4.8964 17.8513
IGROV-1 CTRP2; CTRP1 -3.7538 -2.7843 -3.7638 13.1314
FU-OV-1 CTRP2 -3.6738 -0.4169 -4.3326 14.9983
SNU-119 CTRP2 -3.5044 4.1151 -6.2676 21.9266
SNU-840 CTRP2; CTRP1 -3.2333 -1.9522 -3.3234 9.9453
ES2 CTRP2 -3.1807 -2.8261 -3.1808 9.2838
OV56 CTRP2 -3.1133 -0.3298 -3.7666 11.6238
JHOC-5 CTRP2; CTRP1 -2.9887 -2.2585 -3.0061 8.0642
OV-90 CTRP2; CTRP1 -2.9471 3.3895 -5.3674 17.6102
MCAS CTRP2 -2.901 -1.8504 -2.9859 7.7172
TYK-nu CTRP2; CTRP1 -2.8876 -1.9121 -2.9563 7.5703
OVTOKO CTRP2 -2.3138 -0.4918 -2.9123 5.8574
OVSAHO CTRP2 -1.962 -0.3143 -2.6732 4.0802
SNU-8 CTRP2 -1.8805 -1.2833 -2.1198 1.5963
Kuramochi CTRP2 -1.7781 0.1165 -2.7307 3.9525
Caov-3 CTRP2; CTRP1 -1.0847 1.2095 -2.7472 2.8683
RMG-I CTRP2; CTRP1 -0.6673 6.1301 -4.8547 10.773
COV362 CTRP2; CTRP1 -0.3634 2.7638 -2.9716 3.0607
OVCAR-4 CTRP2; CTRP1 -0.2952 4.4982 -3.7891 5.9277
JHOM-1 CTRP2; CTRP1 0.7818 2.0694 -2.1471 0.0527
SK-OV-3 CTRP2; CTRP1 6.2124 8.2907 4.2729 1.1194
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 -4.7234 -1.6937 -5.0081 20.8937
P-STS CTRP2 -3.5424 2.684 -5.5871 19.8659
SYO-1 CTRP2 0.9173 10.1937 -5.6613 11.5973
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 0.0792 2.1328 -2.4494 0.8336
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2; CTRP1 -3.2585 -1.2055 -3.2588 38.0327
NCI-H28 CTRP2; CTRP1 -3.1565 -1.3735 -3.1565 37.5655
ACC-MESO-1 CTRP2 -2.8627 -1.443 -3.0698 7.9115
MPP 89 CTRP2 -2.8579 1.0451 -4.1452 12.5131
NCI-H2052 CTRP2; CTRP1 -1.3244 6.8138 -2.4549 31.7123
IST-Mes1 CTRP2 -0.5217 5.6449 -4.4706 9.2901
JL-1 CTRP2 0.8388 2.346 -2.2204 0.1057
NCI-H2452 CTRP2 1.0131 3.1145 -2.4741 0.3322
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H660 CTRP2 -9.0787 -6.4157 -9.0844 48.9208
PaCa-3 CTRP2; CTRP1 -6.0295 -4.572 -6.0295 50.8534
LNCaP clone FGC CTRP2 -4.8945 -3.6312 -4.8992 21.0535
DU145 CTRP2 -4.4677 -2.7932 -4.5089 18.3336
VCaP CTRP2 -1.5263 2.56 -3.7125 7.9034
22Rv1 CTRP2 -0.2039 2.1668 -2.6516 1.4913
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 -3.3135 -2.9224 -3.3136 10.1678
A-253 CTRP2 1.0481 2.979 -2.3644 0.2411
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 CTRP2 -9.1931 -8.6726 -9.1931 49.6784
NCC-StC-K140 CTRP2 -7.7919 -0.049 -8.8723 42.4357
SNU-16 CTRP2 -7.653 -6.7956 -7.653 39.4171
SNU-1 CTRP2 -6.9753 -5.5869 -6.9756 34.9031
SNU-216 CTRP2 -6.9675 -5.3643 -6.9686 34.8537
SNU-601 CTRP2 -6.6934 -4.7593 -6.6997 33.0449
GSS CTRP2 -6.2446 -5.7307 -6.2446 29.6757
LMSU CTRP2 -5.5675 -3.3497 -5.6119 25.6714
HuG1-N CTRP2 -5.5609 -3.0298 -5.6413 25.7502
NCI-N87 CTRP2 -5.4908 -3.5936 -5.5141 24.7372
KATO III CTRP2 -5.1621 -1.4642 -5.5529 24.1867
IM95 CTRP2 -4.2526 -2.3501 -4.3426 17.0688
GSU CTRP2 -3.9862 -3.6025 -3.9862 14.645
23132/87 CTRP2 -3.9134 -3.0577 -3.9167 14.1713
Hs 746.T CTRP2 -3.8852 -2.3952 -3.94 14.4992
ECC12 CTRP2 -3.8848 -3.0559 -3.8877 13.9794
SH-10-TC CTRP2; CTRP1 -3.7465 3.3216 -4.1383 41.0518
MKN74 CTRP2; CTRP1 -3.6404 0.9848 -3.7068 39.9129
SNU-620 CTRP2 -3.4507 -2.7786 -3.4533 11.0892
MKN1 CTRP2 -3.1048 -2.3493 -3.1193 8.8271
MKN45 CTRP2 -3.0854 -2.6012 -3.0866 8.6533
NUGC-3 CTRP2 -2.4638 -1.0567 -2.8013 5.7817
AGS CTRP2; CTRP1 -2.3609 0.3323 -3.3555 7.7911
SNU-668 CTRP2 -2.103 -1.3605 -2.2983 2.8532
Fu97 CTRP2; CTRP1 -1.577 8.1373 -3.2071 33.7772
NUGC-4 CTRP2; CTRP1 -1.3398 -0.3764 -1.3398 29.2587
MKN7 CTRP2; CTRP1 -0.6327 2.9804 -0.7328 26.3353
ECC10 CTRP2 0.2418 2.5285 -2.5789 0.9229
SNU-5 CTRP2 0.3778 1.7856 -2.2408 0.1432
SNU-719 CTRP2 1.1147 2.7589 -2.3123 0.1022
KE-39 CTRP2 1.5113 3.7314 -2.4574 0.264
SNU-685 CTRP2 -6.2358 -5.711 -6.2358 29.9745
SNG-M CTRP2; CTRP1 -4.3159 -3.6653 -4.3159 42.867
SNU-1077 CTRP2 -1.7325 -0.0626 -2.6035 3.3318
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FTC-238 CTRP2 -7.0313 -6.4555 -7.0313 35.275
SW579 CTRP2 -6.9974 -6.4791 -6.9974 35.0489
TT2609-C02 CTRP2 -5.991 -4.628 -5.9923 28.3483
CGTH-W-1 CTRP2 -5.3459 -4.8142 -5.3459 23.6945
B-CPAP CTRP2 -4.1094 -3.5574 -4.1095 15.4649
8505C CTRP2 -3.1048 -2.1984 -3.1372 8.8886
TT CTRP2 -2.9546 -1.9956 -3.0108 7.9714
8305C CTRP2 -2.352 -1.0111 -2.7076 5.1214
FTC-133 CTRP2 -2.1283 -0.4993 -2.706 4.8979
ML-1 [Human leukemia] CTRP2 0.6511 2.5028 -2.3931 0.3029
BHT-101 CTRP2 0.9556 2.5306 -2.2905 0.103
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FaDu CTRP2 -7.1469 -6.6538 -7.1469 36.0455
PE/CA-PJ34 (clone C12) CTRP2 -6.9944 -6.2521 -6.9944 35.029
HSC-2 CTRP2; CTRP1 -6.4894 -4.498 -6.4894 52.9627
CAL-33 CTRP2 -6.0316 -5.2725 -6.0316 28.6139
CAL-27 CTRP2 -5.9096 -5.1122 -5.9096 27.8015
YD-8 CTRP2 -5.2608 -4.7845 -5.2608 23.1283
YD-10B CTRP2 -5.2141 -4.7908 -5.2141 22.8172
PE/CA-PJ49 CTRP2 -4.9008 -3.3616 -4.9159 21.1307
SNU-1214 CTRP2 -4.816 -3.577 -4.8213 20.1853
PE/CA-PJ41 (clone D2) CTRP2 -4.7982 -1.9342 -5.0261 21.1879
BICR 22 CTRP2 -4.3317 -3.2571 -4.3365 17.3044
BICR 31 CTRP2 -4.2655 -1.2746 -4.6353 18.1613
HSC-4 CTRP2 -4.0911 -3.5649 -4.0911 15.3427
SCC-9 CTRP2; CTRP1 -3.9883 -1.775 -4.1836 15.6821
SNU-1066 CTRP2 -3.8032 -2.6374 -3.8264 13.5047
PE/CA-PJ15 CTRP2 -3.1534 -0.436 -3.7624 11.7131
BHY CTRP2 -3.0417 -1.3778 -3.286 9.2367
HSC-3 CTRP2 -3.0332 -2.0471 -3.0857 8.4818
SCC-25 CTRP2 -3.0208 -0.5995 -3.5741 10.2894
SNU-899 CTRP2 -2.9073 -1.9097 -2.9782 7.709
SNU-1076 CTRP2 -2.8485 -1.6988 -2.9704 7.5018
SNU-46 CTRP2 -2.1668 -0.4451 -2.7952 5.0352
Detroit 562 CTRP2 -1.9507 -1.0078 -2.3195 2.5804
BICR 18 CTRP2 -1.741 -0.1424 -2.5376 3.3736
BICR 16 CTRP2 -1.0144 1.721 -2.9071 3.687
BICR 6 CTRP2 0.3287 1.4 -2.0784 0.0466
SCC-4 CTRP2 0.5498 8.5901 -5.1412 10.2377
BICR 56 CTRP2 0.667 3.5866 -2.7626 1.3429
SNU-1041 CTRP2 1.1806 3.0689 -2.3951 0.1785
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-BLC1 CTRP2 -6.4375 -5.2821 -6.4376 31.3191
JMSU-1 CTRP2 -6.27 -5.8154 -6.27 29.8448
647V CTRP2 -5.8694 -4.442 -5.8717 27.5411
KU-19-19 CTRP2 -5.1327 -4.6612 -5.1327 22.2753
J82 CTRP2 -4.4316 -2.6104 -4.4934 18.1635
HT-1197 CTRP2 -4.3938 -1.5328 -4.6946 18.7612
UM-UC-1 CTRP2 -4.3455 -3.1044 -4.3566 17.4173
UM-UC-3 CTRP2; CTRP1 -3.9595 -3.1334 -3.9595 41.2374
HT-1376 CTRP2; CTRP1 -3.8499 -2.5554 -3.8499 40.7361
639V CTRP2 -3.7985 -3.0799 -3.7999 13.4001
RT-112 CTRP2 -3.2442 -2.8308 -3.2443 9.7064
VM-CUB-1 CTRP2 -3.2193 -2.2859 -3.2474 9.6355
TCCSUP CTRP2 -3.1169 -2.2538 -3.1426 8.946
SW1710 CTRP2 -3.0863 -1.8871 -3.1787 8.9757
KMBC-2 CTRP2; CTRP1 -2.7912 -1.8415 -2.7912 36.0022
SCaBER CTRP2 -2.7759 -0.494 -3.3485 9.0895
253J CTRP2 -2.4664 -1.329 -2.689 5.3491
5637 CTRP2; CTRP1 -2.29 -1.5074 -2.29 33.6034
CAL-29 CTRP2 -1.3781 2.0618 -3.3814 5.9533
BC-3C CTRP2 0.2072 1.6928 -2.2244 0.2471
T24 CTRP2 0.6029 5.3644 -3.579 4.2173
253J-BV CTRP2 0.8572 2.7326 -2.3966 0.2512
RT-4 CTRP2; CTRP1 1.627 7.2502 0.5501 18.4032
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 -6.1027 -5.727 -6.1027 28.9629

References

1 Anticancer agent CHS-828 inhibits cellular synthesis of NAD. Biochem Biophys Res Commun. 2008 Mar 21;367(4):799-804.