Details of the Drug

General Information of Drug (ID: DMTVY6K)

Drug Name
PGI-02749
Synonyms
PGI-02776; ZJ-11; ZJ-17; ZJ-43; NAAG peptidase inhibitors (brain injury, schizophrenia, pain); GCPII inhibitors (brain injury, schizophrenia, pain), PsychoGenics; Glutamate carboxypeptidase II inhibitors (brain injury, schizophrenia, pain), PsychoGenics; NAAG peptidase inhibitors (brain injury, schizophrenia, pain), PsychoGenics; N-acetylaspartylglutamate peptidase inhibitors (brain injury, schizophrenia, pain), PsychoGenics
Indication
Disease Entry ICD 11 Status REF
Brain injury NA07.Z Investigative [1]
Structure 3D Structure is Not Available
3D MOL 2D MOL
Cross-matching ID
TTD ID
D06LAX

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glutamate carboxypeptidase II (GCPII) TT9G4N0 FOLH1_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Brain injury
ICD Disease Classification NA07.Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glutamate carboxypeptidase II (GCPII) DTT FOLH1 1.40E-09 2.08 2.21
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1606).