Details of the Drug

General Information of Drug (ID: DMTW9GM)

Drug Name
GW-2580
Synonyms GW2580; cFMS receptor tyrosine kinase inhibitor; GW632580X
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 366.4
Logarithm of the Partition Coefficient (xlogp) 2.6
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C20H22N4O3
IUPAC Name
5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine
Canonical SMILES
COC1=CC=C(C=C1)COC2=C(C=C(C=C2)CC3=CN=C(N=C3N)N)OC
InChI
InChI=1S/C20H22N4O3/c1-25-16-6-3-13(4-7-16)12-27-17-8-5-14(10-18(17)26-2)9-15-11-23-20(22)24-19(15)21/h3-8,10-11H,9,12H2,1-2H3,(H4,21,22,23,24)
InChIKey
MYQAUKPBNJWPIE-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
11617559
CAS Number
870483-87-7
TTD ID
D0D6MH

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
CSF1R messenger RNA (CSF1R mRNA) TTVW6QL CSF1R_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
CSF1R messenger RNA (CSF1R mRNA) DTT CSF1R 1.99E-05 0.39 0.56
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 6.6072 14.4915 0.9927 16.5615
EW-7 GDSC1 5.2078 7.1306 3.5693 3.3899
EW-13 GDSC1 5.4019 8.1384 3.2212 5.4502
A-673 GDSC1 5.4145 8.5636 3.028 6.8288
CAL-72 GDSC1 5.7082 8.6207 3.1885 4.9762
SK-PN-DW GDSC1 5.7206 7.804 3.562 2.4413
TC-71 GDSC1 5.7545 7.6042 3.6649 1.7627
SJSA-1 GDSC1 5.7897 8.3319 3.3677 3.5802
MG-63 GDSC1 5.8936 7.9209 3.602 1.9285
CAL-78 GDSC1 6.0572 8.0072 3.6461 1.4683
HOS GDSC1 6.1085 7.3273 3.9265 0.2714
SK-ES-1 GDSC1 6.3283 8.2171 3.6854 0.994
HuO9 GDSC1 6.3527 9.0186 3.3722 2.6028
EW-24 GDSC1 6.3758 8.0066 3.7845 0.5655
CHSA0011 GDSC1 6.3905 8.8187 3.474 1.9753
ES5 GDSC1 6.4281 8.9314 3.4459 2.0805
ES8 GDSC1 6.4408 8.3392 3.6866 0.8919
ES6 GDSC1 6.4525 9.2425 3.3284 2.7125
CADO-ES1 GDSC1 6.4646 8.0813 3.7922 0.4869
ES1 GDSC1 6.4963 8.3948 3.6888 0.8384
SaOS-2 GDSC1 6.6139 8.1671 3.8183 0.3387
CHSA8926 GDSC1 6.6833 8.5755 3.6977 0.6721
HuO-3N1 GDSC1 6.7377 8.8845 3.6043 0.989
NOS-1 [Human HNSCC] GDSC1 6.822 10.6595 2.9142 4.6243
EW-1 GDSC1 6.8889 9.0746 3.5954 0.9076
EW-16 GDSC1 6.9017 8.958 3.644 0.72
MHH-ES-1 GDSC1 6.9315 8.3469 3.8698 0.139
NY GDSC1 7.0056 11.861 2.4844 6.9621
CHSA0108 GDSC1 7.0089 9.1962 3.599 0.8097
G-292 clone A141B1 GDSC1 7.0906 9.014 3.6968 0.4533
ES4 GDSC1 7.1811 9.4497 3.5744 0.7846
U2OS GDSC1 7.2869 9.1097 3.7353 0.2868
H-EMC-SS GDSC1 7.3446 9.6762 3.5561 0.7465
EW-18 GDSC1 7.3485 9.1095 3.7573 0.2269
ES7 GDSC1 7.3842 10.1143 3.4089 1.2656
EW-3 GDSC1 7.4143 9.7264 3.5651 0.678
EW-11 GDSC1 7.5579 9.8854 3.563 0.6094
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 146 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 6.7655 8.4277 3.7827 0.3669
GDM-1 GDSC1 -2.9381 2.5078 -3.1897 75.1691
MY-M12 GDSC1 1.8169 4.796 1.4454 33.5012
L-1236 GDSC1 4.2001 6.063 3.3479 8.1338
Karpas-231 GDSC1 5.0422 6.4313 3.7899 2.1938
RPMI-6666 GDSC1 5.0784 7.423 3.3475 5.3348
OCI-Ly19 GDSC1 5.1836 14.3503 0.0065 25.1505
Hs 445 GDSC1 5.2373 7.1099 3.5968 3.1306
Granta-519 GDSC1 5.3605 8.1565 3.1858 5.8105
SU-DHL-5 GDSC1 5.3714 9.2218 2.6819 9.4671
OCI-AML-2 GDSC1 5.4642 6.6916 3.8997 0.8497
MC116 GDSC1 5.4749 6.3397 4.0387 0.2561
BC-1 GDSC1 5.4785 11.3083 1.7395 15.5064
YT GDSC1 5.5035 7.7133 3.4804 3.3822
JJN-3 GDSC1 5.5174 7.3145 3.6653 2.1316
OCI-M1 GDSC1 5.5528 7.7533 3.4911 3.2111
BC-3 GDSC1 5.6022 7.4368 3.6576 2.0396
Ramos.2G6.4C10 GDSC1 5.6337 9.3341 2.8067 7.8677
SCC-3 GDSC1 5.653 7.551 3.6353 2.0951
OCI-AML-3 GDSC1 5.6625 9.5646 2.7161 8.4383
SUP-B15 GDSC1 5.6638 7.5823 3.6275 2.1257
NB4 GDSC1 5.6984 7.0869 3.8491 0.8476
RPMI-8226 GDSC1 5.761 8.0999 3.4546 3.0601
LC4-1 GDSC1 5.7669 10.5665 2.3064 11.0025
WSU-DLCL2 GDSC1 5.7725 7.5129 3.7119 1.4712
MOLP-8 GDSC1 5.7819 7.9689 3.5233 2.5817
HL-60 GDSC1 5.7912 7.1865 3.8511 0.7485
P12-Ichikawa GDSC1 5.8122 7.5162 3.7296 1.3243
KMS-11 GDSC1 5.8144 9.2866 2.9458 6.4407
ALL-PO GDSC1 5.8164 11.1547 2.0566 12.5204
SU-DHL-10 GDSC1 5.8274 6.7799 4.0148 0.1656
EoL-1 GDSC1 5.8447 8.4642 3.34 3.6593
TK [Human B-cell lymphoma] GDSC1 5.8762 7.7778 3.6531 1.6609
SUP-M2 GDSC1 5.879 6.9533 3.973 0.2479
KE-37 GDSC1 5.8858 6.9068 3.9919 0.1973
RL GDSC1 5.8934 8.5512 3.3288 3.6415
BALL-1 GDSC1 5.9138 7.6031 3.742 1.1414
BE-13 GDSC1 5.9166 9.3759 2.968 6.0525
Sc-1 GDSC1 5.9296 8.3145 3.4527 2.7776
H9 GDSC1 5.9575 8.5183 3.379 3.1978
OPM-2 GDSC1 5.9855 7.6809 3.7437 1.0566
697 GDSC1 6.0116 7.9174 3.661 1.4446
WIL2 NS GDSC1 6.0131 7.7156 3.7424 1.0346
TUR GDSC1 6.0194 9.5954 2.9297 6.0888
MV4-11 GDSC1 6.0256 7.8898 3.6787 1.336
KMOE-2 GDSC1 6.027 7.7648 3.7292 1.0834
EB2 GDSC1 6.0427 7.8 3.7223 1.1
P31/FUJ GDSC1 6.0514 7.2312 3.9391 0.2628
HT GDSC1 6.0522 7.8034 3.7253 1.076
HEL GDSC1 6.0831 7.3898 3.8945 0.375
SUP-T1 GDSC1 6.0832 8.656 3.387 2.9332
ME1 GDSC1 6.099 7.4425 3.8816 0.4069
SU-DHL-1 GDSC1 6.1006 7.2837 3.9389 0.243
Raji GDSC1 6.1137 7.2539 3.9541 0.2021
SU-DHL-16 GDSC1 6.1338 7.6019 3.837 0.537
MHH-PREB-1 GDSC1 6.1433 9.3738 3.1039 4.6528
RC-K8 GDSC1 6.1535 7.4705 3.8925 0.3448
A3/Kawakami GDSC1 6.1681 7.5658 3.8638 0.4251
Namalwa GDSC1 6.172 7.7522 3.7965 0.6615
ATN-1 GDSC1 6.1878 7.9507 3.7275 0.935
Karpas-299 GDSC1 6.1945 8.0028 3.7102 1.0064
SU-DHL-4 GDSC1 6.2139 7.6993 3.8331 0.4995
KY821 GDSC1 6.2198 7.6296 3.8607 0.406
DB GDSC1 6.2221 8.3859 3.5703 1.6686
L-363 GDSC1 6.2243 7.4614 3.9222 0.2359
JVM-3 GDSC1 6.2299 8.2149 3.6427 1.2895
MLMA GDSC1 6.2307 7.9419 3.7492 0.8052
HDLM-2 GDSC1 6.2394 8.7971 3.4081 2.5597
GR-ST GDSC1 6.2497 8.751 3.4327 2.3999
Kasumi-1 GDSC1 6.2502 11.8919 1.9983 11.7416
SK-MM-2 GDSC1 6.2562 8.1695 3.6724 1.1208
RPMI-8866 GDSC1 6.2575 8.7372 3.4424 2.3322
Daudi GDSC1 6.2596 7.5916 3.8895 0.3039
LP-1 GDSC1 6.2629 8.5438 3.5253 1.8597
K-562 GDSC1 6.2708 8.06 3.7212 0.8894
Karpas-422 GDSC1 6.2721 7.503 3.9251 0.2122
Loucy GDSC1 6.2775 7.6166 3.8873 0.3017
Jiyoye GDSC1 6.2904 7.8383 3.8124 0.5228
KOPN-8 GDSC1 6.2961 8.0862 3.7219 0.8648
HH [Human lymphoma] GDSC1 6.3363 8.9968 3.373 2.6223
A4/Fukuda GDSC1 6.3479 7.8302 3.8377 0.4086
ST486 GDSC1 6.3522 7.9133 3.8093 0.4958
ROS-50 GDSC1 6.3557 9.9109 2.9852 5.0233
Ku812 GDSC1 6.3655 8.0878 3.7502 0.6972
EJM GDSC1 6.3747 7.8456 3.8425 0.381
ML-2 GDSC1 6.3757 8.0793 3.7575 0.6625
VAL GDSC1 6.3758 8.9935 3.3943 2.4411
SR GDSC1 6.3785 12.7259 1.6857 13.3229
DEL GDSC1 6.381 7.4659 3.9759 0.0946
SU-DHL-8 GDSC1 6.4015 7.9982 3.7977 0.505
ARH-77 GDSC1 6.414 8.0802 3.7726 0.5825
KG-1 GDSC1 6.4322 8.2333 3.7231 0.7524
BL-41 GDSC1 6.4419 7.6946 3.9199 0.1709
RS4;11 GDSC1 6.4447 8.0259 3.8045 0.4589
EM-2 GDSC1 6.4479 7.8127 3.8814 0.2492
MOLT-13 GDSC1 6.466 8.2655 3.7249 0.7208
THP-1 GDSC1 6.4711 11.5545 2.3013 9.2691
NOMO-1 GDSC1 6.4871 7.7636 3.9123 0.1727
KM-H2 GDSC1 6.4898 7.9048 3.8645 0.2732
JURL-MK1 GDSC1 6.4947 8.0165 3.827 0.3678
SU-DHL-6 GDSC1 6.5074 7.8855 3.8777 0.2368
P32/ISH GDSC1 6.5086 7.9761 3.8465 0.3102
U266B1 GDSC1 6.5367 8.2582 3.756 0.5632
Farage GDSC1 6.5417 7.9661 3.8621 0.2598
MOLT-16 GDSC1 6.5426 8.0705 3.8258 0.3495
KCL-22 GDSC1 6.5467 8.1409 3.8023 0.4129
DG-75 GDSC1 6.5476 8.5607 3.6474 0.9669
NU-DUL-1 GDSC1 6.5477 14.9715 0.7188 18.0802
L-540 GDSC1 6.5486 8.1928 3.7844 0.4654
L-428 GDSC1 6.5505 8.1869 3.7873 0.4556
U-698-M GDSC1 6.561 8.4218 3.7053 0.7269
MN-60 GDSC1 6.5728 8.9585 3.5031 1.6071
PL-21 GDSC1 6.5764 9.1548 3.4256 2.0021
CA46 GDSC1 6.5875 8.7598 3.5879 1.19
CTV-1 GDSC1 6.5944 8.0413 3.8551 0.2571
WSU-NHL GDSC1 6.6127 7.9713 3.8858 0.1879
LAMA-84 GDSC1 6.614 8.6865 3.6275 0.9947
CESS GDSC1 6.6186 8.2691 3.7838 0.4314
AMO1 GDSC1 6.6237 15.1424 0.6892 18.0248
DND-41 GDSC1 6.65 8.4851 3.7177 0.6237
Karpas-620 GDSC1 6.6694 8.1463 3.8459 0.2518
ALL-SIL GDSC1 6.6705 8.1273 3.8528 0.2365
Reh GDSC1 6.6791 8.4575 3.7392 0.5355
RPMI-8402 GDSC1 6.6891 8.2603 3.8133 0.3205
MOLM-13 GDSC1 6.7003 8.3367 3.7906 0.3743
SUP-HD1 GDSC1 6.7212 8.7075 3.6641 0.7683
Karpas-45 GDSC1 6.7348 8.6521 3.69 0.6661
NALM-6 GDSC1 6.7461 8.3802 3.7923 0.3504
QIMR-WIL GDSC1 6.7588 9.6577 3.3073 2.409
HC-1 GDSC1 6.7679 8.4331 3.7817 0.3685
BV-173 GDSC1 6.777 8.4974 3.7624 0.4165
KMS-12-BM GDSC1 6.8001 8.2122 3.8697 0.1681
CCRF-CEM GDSC1 6.8941 8.556 3.7851 0.3102
MEG-01 GDSC1 6.8978 8.9073 3.6611 0.664
P30/OHK GDSC1 6.9214 8.4538 3.8302 0.2073
MOLT-4 GDSC1 6.9334 8.6279 3.7745 0.3207
JSC-1 GDSC1 6.9442 13.6231 1.633 12.2415
PF-382 GDSC1 6.9499 8.6673 3.7667 0.3329
HAL-01 GDSC1 6.9613 8.6867 3.7641 0.3348
CTB-1 GDSC1 7.0098 16.1419 0.4743 18.056
VL51 GDSC1 7.0553 14.1134 1.4737 12.8817
JVM-2 GDSC1 7.2276 9.3651 3.6234 0.5982
SIG-M5 GDSC1 7.2871 14.3522 1.51 12.1502
NKM-1 GDSC1 7.4962 21.5023 -1.7879 25.1041
Mono-Mac-6 GDSC1 7.5555 10.2334 3.4349 1.0354
OCI-AML-5 GDSC1 7.7698 22.1236 -1.8948 24.8086
⏷ Show the Full List of 146 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-50 GDSC1 5.1433 8.7396 2.7546 9.5921
HCE-4 GDSC1 6.0932 9.2314 3.139 4.5177
ESO-51 GDSC1 6.1624 8.2429 3.6002 1.5831
KYAE-1 GDSC1 6.5759 8.3302 3.7451 0.5761
ESO-26 GDSC1 6.6817 8.1512 3.8486 0.2419
SK-GT-4 GDSC1 6.7519 8.8958 3.606 0.9709
TE-12 GDSC1 6.846 12.2972 2.19 9.1278
KYSE-220 GDSC1 7.2665 9.0692 3.742 0.2794
FLO-1 GDSC1 7.3612 10.1476 3.3865 1.3782
OACM5.1 C GDSC1 7.4748 9.8192 3.5549 0.6768
OACP4 C GDSC1 7.4947 9.3829 3.7156 0.2644
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 6.8167 8.7315 3.6933 0.6049
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-7 GDSC1 5.4724 9.6998 2.521 10.3328
SJNB-10 GDSC1 5.6694 9.8236 2.5969 9.2618
SK-N-FI GDSC1 5.6934 7.8567 3.5242 2.7292
IMR-5 GDSC1 5.6982 7.6139 3.632 2.0435
SK-N-MC-IXC GDSC1 5.7955 6.9728 3.9337 0.4149
SK-N-DZ GDSC1 5.8382 7.2756 3.837 0.7681
NB(TU)1 GDSC1 5.954 7.6932 3.7245 1.1848
SJNB-5 GDSC1 6.0978 8.2992 3.5458 1.9647
CHP-134 GDSC1 6.1034 7.7364 3.7737 0.8091
GOTO GDSC1 6.1078 8.8589 3.3121 3.3627
SJNB-13 GDSC1 6.1506 8.1216 3.6435 1.3725
NH-12 GDSC1 6.2159 8.0896 3.6858 1.0979
SK-N-BE(2)-M17 GDSC1 6.2395 8.6058 3.4883 2.0954
SJNB-17 GDSC1 6.2784 11.7571 2.0812 11.1462
KP-N-YN GDSC1 6.3093 8.7183 3.4759 2.0707
CHP-212 GDSC1 6.3139 8.2654 3.6604 1.1199
TGW GDSC1 6.3258 8.2176 3.6841 1.0017
CHP-126 GDSC1 6.3812 8.003 3.788 0.5501
SK-N-AS GDSC1 6.3865 11.0661 2.4758 8.3267
Kelly GDSC1 6.3983 7.606 3.9347 0.1554
MHH-NB-11 GDSC1 6.4798 8.0707 3.8019 0.4482
LA-N-6 GDSC1 6.6439 8.4597 3.7246 0.6041
SJNB-6 GDSC1 6.7153 8.3513 3.791 0.3666
SiMa GDSC1 6.7376 8.8645 3.6118 0.9585
NB1 GDSC1 6.859 14.5087 1.1563 15.075
SJNB-14 GDSC1 6.8937 8.278 3.8799 0.1318
SK-N-SH GDSC1 6.932 13.2538 1.7987 11.3061
NB69 GDSC1 7.0407 8.7562 3.7688 0.2954
GI-ME-N GDSC1 7.0802 9.7394 3.4226 1.4726
KP-N-YS GDSC1 7.1076 8.9197 3.7363 0.3459
SJNB-12 GDSC1 7.1098 8.9292 3.7338 0.3511
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 6.7819 12.8491 1.8927 11.0939
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUB-M GDSC1 4.299 6.6629 3.1323 9.4574
HCC2218 GDSC1 5.0811 9.0831 2.5406 11.3423
Evsa-T GDSC1 5.1439 7.4419 3.3823 4.9058
MDA-MB-415 GDSC1 5.391 8.6944 2.9497 7.463
HCC1599 GDSC1 5.4679 8.606 3.0432 6.5819
HCC2157 GDSC1 5.4837 9.3252 2.7098 8.956
BT-20 GDSC1 5.53 7.5318 3.5768 2.6816
HCC1187 GDSC1 5.5449 8.8244 2.9901 6.7737
BT-474 GDSC1 5.5803 8.5787 3.1286 5.6919
HCC1500 GDSC1 5.7286 8.4404 3.2833 4.2742
HCC1419 GDSC1 5.798 7.8307 3.5913 2.135
ZR-75-30 GDSC1 5.8415 8.3934 3.3697 3.4686
CAMA-1 GDSC1 5.858 8.834 3.1811 4.7076
MDA-MB-453 GDSC1 5.9034 10.2583 2.5457 9.0136
MDA-MB-436 GDSC1 5.9601 9.1356 3.1045 5.0188
JIMT-1 GDSC1 6.0401 7.7683 3.7337 1.0483
EFM-19 GDSC1 6.0553 8.3084 3.5207 2.1689
UACC-812 GDSC1 6.1103 7.9472 3.6947 1.163
CAL-51 GDSC1 6.1549 8.2935 3.576 1.722
HDQ-P1 GDSC1 6.1598 8.0459 3.6779 1.1922
HCC1954 GDSC1 6.1685 9.3961 3.1084 4.5745
UACC-893 GDSC1 6.1711 8.4038 3.5384 1.9069
MDA-MB-231 GDSC1 6.1779 9.4604 3.085 4.711
DU4475 GDSC1 6.1792 7.6345 3.8431 0.4867
Hs 578T GDSC1 6.2119 8.2316 3.6278 1.3831
MDA-MB-468 GDSC1 6.2146 10.7433 2.5182 8.4431
MCF-7 GDSC1 6.2804 7.9233 3.7769 0.6573
CAL-148 GDSC1 6.2868 7.962 3.765 0.6981
MDA-MB-175-VII GDSC1 6.2984 8.101 3.7172 0.8825
MDA-MB-330 GDSC1 6.3265 9.8205 3.0089 4.9241
BT-549 GDSC1 6.3579 9.614 3.1181 4.1586
CAL-120 GDSC1 6.3611 7.7071 3.8864 0.2696
AU565 GDSC1 6.3997 9.1827 3.3268 2.8004
CAL-85-1 GDSC1 6.4056 8.6232 3.5603 1.5063
YMB-1-E GDSC1 6.4138 10.3308 2.8299 5.9282
BT-483 GDSC1 6.4817 8.2015 3.755 0.6008
HCC70 GDSC1 6.5083 8.135 3.7897 0.4706
HCC1937 GDSC1 6.5796 8.3046 3.7559 0.5382
MRK-nu-1 GDSC1 6.5869 7.7213 3.9608 0.0798
HCC38 GDSC1 6.6502 8.6124 3.6706 0.7941
HCC1569 GDSC1 6.6888 9.4204 3.3708 2.1548
MFM-223 GDSC1 6.7208 8.3944 3.7778 0.3998
HCC1395 GDSC1 6.7459 8.5928 3.7161 0.5717
EFM-192A GDSC1 6.7552 8.6359 3.704 0.6059
MDA-MB-361 GDSC1 6.7617 8.2969 3.8271 0.2619
HCC1428 GDSC1 6.7627 8.2409 3.8467 0.2205
MDA-MB-157 GDSC1 6.8474 12.1845 2.2429 8.7957
T-47D GDSC1 7.1686 8.9258 3.7563 0.2805
HCC1806 GDSC1 7.3525 8.6727 3.9035 0.0483
COLO 824 GDSC1 7.5055 9.4743 3.6881 0.3162
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GB-1 GDSC1 4.775 11.3559 1.175 21.0634
YKG-1 GDSC1 5.5463 7.3981 3.6445 2.2142
SF295 GDSC1 5.5576 7.3183 3.685 1.9419
D-566MG GDSC1 5.6147 7.9329 3.446 3.3941
D-423MG GDSC1 5.7268 9.0639 2.9945 6.3022
SW1783 GDSC1 5.7677 8.7118 3.1829 4.8863
GaMG GDSC1 5.7804 8.071 3.478 2.8732
D-336MG GDSC1 5.8114 9.3009 2.9372 6.5078
LN-18 GDSC1 5.8159 6.8614 3.9819 0.2521
U-87MG ATCC GDSC1 5.8348 7.4404 3.7707 1.0851
U-251MG GDSC1 5.9566 7.7227 3.7139 1.2354
Daoy GDSC1 6.0085 8.4155 3.451 2.6587
Hs 683 GDSC1 6.0952 7.2181 3.9598 0.1958
A-172 GDSC1 6.1403 8.3554 3.5434 1.9204
Onda 11 GDSC1 6.1736 9.8194 2.9201 5.8226
AM-38 GDSC1 6.1814 8.1687 3.6389 1.3612
KNS-42 GDSC1 6.2097 7.5054 3.9013 0.2941
SF539 GDSC1 6.2612 7.6111 3.8832 0.3201
DK-MG GDSC1 6.2644 7.4781 3.9309 0.2021
SK-MG-1 GDSC1 6.2657 8.3582 3.6019 1.4535
Becker GDSC1 6.2662 9.5209 3.1082 4.3905
YH-13 GDSC1 6.2831 7.6609 3.8737 0.3361
LNZTA3WT4 GDSC1 6.2857 8.6173 3.5061 1.935
PFSK-1 GDSC1 6.3192 8.2392 3.6729 1.0579
M059J GDSC1 6.3416 8.1942 3.6999 0.9194
D-542MG GDSC1 6.3471 8.2953 3.6633 1.075
GI-1 GDSC1 6.35 8.0174 3.7701 0.6336
CAS-1 GDSC1 6.3868 13.7531 1.1966 16.0669
NMC-G1 GDSC1 6.3943 8.2345 3.7069 0.8464
D-263MG GDSC1 6.3956 7.6845 3.9068 0.2107
Onda 10 GDSC1 6.4437 8.4904 3.6297 1.1359
42-MG-BA GDSC1 6.4694 7.8679 3.8699 0.268
D-502MG GDSC1 6.4769 9.0827 3.4072 2.2293
D283 Med GDSC1 6.502 7.8824 3.8768 0.2406
MOG-G-CCM GDSC1 6.514 9.0447 3.4408 1.9987
U-118MG GDSC1 6.5514 10.4492 2.8563 5.4839
MOG-G-UVW GDSC1 6.5815 8.8556 3.5478 1.3808
LN-229 GDSC1 6.6042 8.2798 3.7745 0.4663
T98G GDSC1 6.6058 8.0508 3.8559 0.2513
DBTRG-05MG GDSC1 6.6394 8.2531 3.7974 0.3831
LN-405 GDSC1 6.6449 21.937 -2.6325 29.1986
SF268 GDSC1 6.6554 9.4526 3.3416 2.3561
D-247MG GDSC1 6.8101 8.7911 3.6689 0.6918
D-392MG GDSC1 6.8123 9.2247 3.5055 1.3505
SF126 GDSC1 6.8298 8.0518 3.9334 0.0761
KS-1 [Human Krukenberg tumour] GDSC1 6.8537 13.7975 1.4916 13.2604
KALS-1 GDSC1 6.8722 9.7396 3.3281 2.1561
8-MG-BA GDSC1 6.932 12.8204 2.0009 10.0979
SW1088 GDSC1 6.9611 8.5195 3.8218 0.2121
ONS-76 GDSC1 7.0299 8.6407 3.8047 0.2252
KINGS-1 GDSC1 7.0503 9.4881 3.5065 1.1369
H4 GDSC1 7.0778 8.7456 3.7858 0.2481
KNS-81-FD GDSC1 7.1505 11.5003 2.7258 5.2108
SNB-75 GDSC1 7.1526 9.1574 3.6692 0.5013
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1 6.1327 7.7568 3.7783 0.765
TGBC24TKB GDSC1 6.2831 9.8295 2.9799 5.1999
ETK-1 GDSC1 7.52 9.7307 3.6038 0.5129
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EN GDSC1 6.0097 9.2254 3.093 4.9937
MFE-296 GDSC1 6.0832 9.6689 2.9347 5.9162
RL95-2 GDSC1 6.179 9.4824 3.0757 4.7701
MFE-319 GDSC1 6.3652 8.147 3.7278 0.7847
AN3-CA GDSC1 6.4203 8.7882 3.5007 1.7957
ESS-1 GDSC1 6.4972 8.2019 3.761 0.5703
KLE GDSC1 7.0482 8.9486 3.7041 0.4527
MFE-280 GDSC1 7.3154 14.1309 1.631 11.4108
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
786-O GDSC1 5.0695 6.7851 3.6436 3.1706
KTCTL-1M GDSC1 5.3957 10.2227 2.2115 12.6973
RCC10RGB GDSC1 5.531 9.484 2.6658 9.1435
A-498 GDSC1 5.5598 8.005 3.3812 3.951
KMRC-1 GDSC1 5.5829 7.5713 3.5887 2.5081
RXF 393L GDSC1 5.7944 10.3294 2.4391 10.0267
A-704 GDSC1 5.8016 9.0309 3.0566 5.6928
OS-RC-2 GDSC1 5.9362 7.6252 3.7434 1.1102
BFTC-909 GDSC1 5.9414 7.4359 3.8197 0.7517
Caki-1 GDSC1 5.9599 8.7539 3.2762 3.8635
KTCTL-13 GDSC1 6.0192 8.3858 3.4694 2.5294
769-P GDSC1 6.0294 10.0689 2.7162 7.5343
VMRC-RCW GDSC1 6.0492 8.7078 3.3462 3.2475
CAL-54 GDSC1 6.1049 9.4704 3.038 5.1706
NCC021 GDSC1 6.182 8.9763 3.301 3.3052
KMRC-20 GDSC1 6.2949 8.2719 3.6494 1.19
UO-31 GDSC1 6.3388 8.8466 3.4373 2.2478
KTCTL-21 GDSC1 6.3472 9.8353 3.0141 4.8505
ACHN GDSC1 6.4157 9.2795 3.2939 2.9713
HA7-RCC GDSC1 6.4785 8.878 3.4917 1.7729
KTCTL-195 GDSC1 6.4788 13.5194 1.3729 14.861
BB65-RCC GDSC1 6.5082 8.5623 3.6299 1.0758
SW13 GDSC1 6.5777 8.2623 3.7706 0.4925
LB2241-RCC GDSC1 6.5899 8.6673 3.6246 1.0272
SN12C GDSC1 6.5915 8.519 3.6815 0.7952
KTCTL-26A GDSC1 6.6592 8.7054 3.6393 0.9095
LB996-RCC GDSC1 6.7258 8.8654 3.6066 0.9893
SW156 GDSC1 6.729 13.4658 1.5669 13.1357
KTCTL-140 GDSC1 6.7758 8.9889 3.5806 1.0556
LB1047-RCC GDSC1 6.7866 9.2349 3.4902 1.4462
TK-10 GDSC1 7.298 9.5527 3.5828 0.6867
VMRC-RCZ GDSC1 8.7263 16.8256 1.2473 10.6208
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KM12 GDSC1 4.3109 9.878 1.5347 20.6968
HT115 GDSC1 5.4313 7.4894 3.5393 3.1245
LS1034 GDSC1 5.4571 7.6109 3.4995 3.3459
MDST8 GDSC1 5.6918 7.0908 3.8446 0.8757
HT-29 GDSC1 5.6994 7.6474 3.6183 2.1255
SNU-61 GDSC1 5.7244 7.5748 3.6621 1.8231
SNU-175 GDSC1 5.7657 9.1777 2.9659 6.4123
LS180 GDSC1 5.8448 7.2959 3.832 0.7843
COLO205 GDSC1 5.9174 7.6617 3.7201 1.2482
SNU-1040 GDSC1 5.9204 7.1768 3.9084 0.4239
SW948 GDSC1 5.965 7.7456 3.7085 1.2529
SW48 GDSC1 5.9791 8.4811 3.407 2.9823
HCT 15 GDSC1 5.9969 8.1418 3.5612 2.0172
SW837 GDSC1 5.9979 11.0884 2.213 11.0115
SW1417 GDSC1 6.0521 8.1298 3.5935 1.7587
SNU-81 GDSC1 6.0651 7.5153 3.8413 0.5681
LS411N GDSC1 6.083 7.646 3.7995 0.7181
CaR-1 GDSC1 6.1257 9.4575 3.0561 5.0067
SW1463 GDSC1 6.1442 8.5622 3.4588 2.4015
SW1116 GDSC1 6.1639 7.8552 3.754 0.841
SNU-C1 GDSC1 6.1817 8.2579 3.6032 1.5444
T84 GDSC1 6.2436 8.7662 3.4232 2.464
SNU-C5 GDSC1 6.257 9.1156 3.2809 3.3053
RCM-1 [Human ESC] GDSC1 6.2986 8.771 3.4488 2.238
CL-11 GDSC1 6.3308 8.4654 3.589 1.4456
LS123 GDSC1 6.426 9.277 3.3003 2.9178
LoVo GDSC1 6.4438 8.667 3.5603 1.4645
COLO 320HSR GDSC1 6.4532 8.6862 3.5569 1.4709
HT-55 GDSC1 6.4747 7.8925 3.8633 0.2819
CCK-81 GDSC1 6.5016 8.4666 3.6638 0.9366
LS513 GDSC1 6.5252 8.1179 3.8024 0.4235
SNU-407 GDSC1 6.5462 8.7291 3.5817 1.2573
HCC2998 GDSC1 6.5676 8.3643 3.7293 0.6357
NCI-H747 GDSC1 6.5958 10.0344 3.0641 4.0839
HCT 116 GDSC1 6.6784 8.9943 3.5364 1.3377
SW620 GDSC1 6.6842 8.4699 3.7367 0.5406
GP5d GDSC1 6.7449 10.4054 2.9832 4.3311
C2BBe1 GDSC1 6.7721 9.1379 3.5217 1.3154
RKO GDSC1 6.7763 8.3151 3.826 0.2593
COLO 678 GDSC1 6.7787 8.4989 3.7625 0.4154
CW-2 GDSC1 6.8262 8.511 3.7759 0.359
NCI-H716 GDSC1 6.8286 8.6174 3.7391 0.4577
SW626 GDSC1 7.0093 9.3282 3.5498 0.9949
SNU-C2B GDSC1 7.3788 10.328 3.3245 1.6334
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 6.3991 12.459 1.8271 12.4214
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-6 GDSC1 4.6082 5.9425 3.736 3.6817
SNU-387 GDSC1 5.4899 8.4291 3.141 5.8183
Hep 3B2.1-7 GDSC1 5.5944 8.0064 3.401 3.7417
JHH-1 GDSC1 6.1157 7.2632 3.9516 0.2071
Hep-G2/C3A GDSC1 6.1264 7.6114 3.8304 0.5658
HLE GDSC1 6.1309 9.1461 3.1984 4.0541
Huh-7 GDSC1 6.1659 8.6477 3.4337 2.518
JHH-7 GDSC1 6.1698 8.2406 3.6045 1.5512
SK-HEP-1 GDSC1 6.2429 7.4105 3.9465 0.1764
SNU-475 GDSC1 6.3542 7.8126 3.8465 0.3795
HuH-1 GDSC1 6.5334 14.5188 0.9282 17.0816
SNU-398 GDSC1 6.5467 8.7948 3.5562 1.3765
JHH-4 GDSC1 6.6541 8.5879 3.6813 0.751
SNU-423 GDSC1 6.8884 12.6168 2.0683 9.7849
JHH-2 GDSC1 7.071 8.9603 3.7085 0.4306
SNU-449 GDSC1 7.4314 9.6402 3.6026 0.5571
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 171 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC78 GDSC1 4.9836 6.8647 3.5507 4.0619
NCI-H1755 GDSC1 5.0022 13.433 0.3201 24.4316
COR-L303 GDSC1 5.0339 6.597 3.7088 2.784
BEN GDSC1 5.0695 7.6585 3.2281 6.2569
NCI-H2029 GDSC1 5.2072 7.4708 3.41 4.5446
SBC-5 GDSC1 5.2671 6.8031 3.7523 2.0106
NCI-H1694 GDSC1 5.2799 25.063 -5.2615 36.7724
NCI-H526 GDSC1 5.3127 9.3731 2.5669 10.4617
NCI-H2444 GDSC1 5.3259 7.1353 3.6377 2.6644
NCI-H1304 GDSC1 5.3682 9.5156 2.5369 10.5156
NCI-H1573 GDSC1 5.3999 8.2257 3.1787 5.7644
ABC-1 GDSC1 5.4961 9.8127 2.4828 10.5345
UMC-11 GDSC1 5.5327 8.334 3.2127 5.2005
COLO 668 GDSC1 5.6185 8.0437 3.3983 3.7112
NCI-H720 GDSC1 5.675 6.9088 3.908 0.6039
CAL-12T GDSC1 5.6861 8.138 3.3952 3.5972
Lu-65 GDSC1 5.6896 8.4835 3.2403 4.655
NCI-H1436 GDSC1 5.7074 10.4544 2.3194 11.0765
NCI-H847 GDSC1 5.7092 7.305 3.7666 1.2536
IA-LM GDSC1 5.7131 7.4703 3.7003 1.6174
NCI-H2373 GDSC1 5.7319 8.8665 3.0896 5.6179
HCC827 GDSC1 5.7337 7.4497 3.719 1.4829
COR-L95 GDSC1 5.7376 10.4461 2.3443 10.8259
DMS 53 GDSC1 5.7595 9.6751 2.7277 8.1093
NCI-H2369 GDSC1 5.7737 7.6419 3.6588 1.771
RERF-LC-MS GDSC1 5.7858 7.7768 3.608 2.0532
NCI-H187 GDSC1 5.7868 6.9883 3.9244 0.4539
NCI-H64 GDSC1 5.8039 7.5232 3.7228 1.3711
NCI-H290 GDSC1 5.8064 19.581 -2.1085 29.9873
NCI-H1435 GDSC1 5.8114 9.0441 3.0565 5.6711
NCI-H1869 GDSC1 5.8297 7.677 3.672 1.6176
LCLC-103H GDSC1 5.8386 7.0733 3.9138 0.4573
NCI-H2081 GDSC1 5.8446 9.6795 2.7809 7.5256
COR-L105 GDSC1 5.8624 8.2911 3.4265 3.0604
NCI-H1770 GDSC1 5.8699 7.74 3.6656 1.5992
HCC33 GDSC1 5.8702 9.9861 2.6529 8.3557
Lu-165 GDSC1 5.9021 7.4966 3.7789 0.9737
NCI-H3255 GDSC1 5.9185 8.0457 3.562 2.1273
NCI-H1648 GDSC1 5.92 8.2406 3.4795 2.6262
HCC44 GDSC1 5.9353 7.8902 3.6355 1.6801
NCI-H1581 GDSC1 5.9363 9.8414 2.7636 7.4263
NCI-H460 GDSC1 5.9436 8.0798 3.5604 2.0994
NCI-H810 GDSC1 5.9521 7.6658 3.7345 1.1369
NCI-H2196 GDSC1 5.9609 7.8388 3.6689 1.4645
NCI-H2804 GDSC1 5.9724 9.2116 3.0772 5.1791
NCI-H1693 GDSC1 6.0029 8.3135 3.4917 2.4194
COR-L88 GDSC1 6.0088 11.2958 2.1209 11.5846
Calu-3 GDSC1 6.0172 7.5507 3.808 0.7369
NCI-H1781 GDSC1 6.0184 7.6013 3.7892 0.8165
SK-MES-1 GDSC1 6.02 8.6479 3.3564 3.2327
LK-2 GDSC1 6.0303 8.6347 3.3678 3.1426
NCI-H1993 GDSC1 6.0574 7.9506 3.6691 1.3488
NCI-H727 GDSC1 6.0808 8.176 3.5884 1.7494
NCI-H358 GDSC1 6.0853 9.6407 2.9488 5.8153
COR-L23 GDSC1 6.1013 7.7483 3.7682 0.8342
NCI-H226 GDSC1 6.1048 8.0294 3.6594 1.3441
NCI-H1092 GDSC1 6.1188 8.0731 3.6483 1.3844
NCI-H522 GDSC1 6.1273 8.3229 3.5504 1.8986
COR-L311 GDSC1 6.1398 8.7926 3.358 3.0198
NCI-H211 GDSC1 6.1447 10.0753 2.7851 6.7999
PaCa-3 GDSC1 6.1512 8.8173 3.3534 3.0296
NCI-H1155 GDSC1 6.1734 7.8496 3.7602 0.807
SK-LU-1 GDSC1 6.1751 8.0417 3.6865 1.1354
NCI-H1836 GDSC1 6.191 31.0835 -7.5349 37.4525
NCI-H838 GDSC1 6.2081 10.392 2.6778 7.3847
IST-SL2 GDSC1 6.2082 8.8238 3.3806 2.7717
NCI-H2803 GDSC1 6.2141 8.8086 3.3901 2.7051
CPC-N GDSC1 6.2246 9.5507 3.0713 4.7105
DMS 79 GDSC1 6.2286 9.6264 3.0397 4.9117
NCI-H1048 GDSC1 6.2485 9.4346 3.1365 4.2396
NCI-H841 GDSC1 6.2571 10.1206 2.8326 6.2348
NCI-H23 GDSC1 6.2578 19.1778 -1.5608 27.3901
NCI-H1623 GDSC1 6.2826 8.8817 3.3943 2.5765
LC-2/ad GDSC1 6.2926 8.3779 3.6064 1.4009
NCI-H2722 GDSC1 6.306 7.8331 3.8204 0.4864
NCI-H1876 GDSC1 6.3091 11.7458 2.1068 10.9067
NCI-H2141 GDSC1 6.3352 17.8451 -0.8439 24.9763
NCI-H2172 GDSC1 6.3535 7.9371 3.8012 0.5221
NCI-H2795 GDSC1 6.3542 8.3778 3.6342 1.202
NCI-H1793 GDSC1 6.3571 8.3541 3.6448 1.1499
NCI-H1734 GDSC1 6.3577 8.0588 3.7579 0.6739
NCI-H1563 GDSC1 6.3603 7.8796 3.8248 0.4418
SHP-77 GDSC1 6.3669 11.8861 2.0782 10.9452
NCI-H2087 GDSC1 6.3684 9.2557 3.2795 3.1327
NCI-H446 GDSC1 6.3774 15.5394 0.3203 20.3725
NCI-H510A GDSC1 6.3796 13.1854 1.4657 14.5975
LC-1/sq GDSC1 6.3876 8.783 3.4872 1.9074
NCI-H1651 GDSC1 6.3881 10.4781 2.7477 6.5241
Ms-1 GDSC1 6.4089 12.1805 1.9662 11.5429
COR-L321 GDSC1 6.4099 7.6026 3.9399 0.1434
Lu-99A GDSC1 6.4333 8.8124 3.497 1.7993
EBC-1 GDSC1 6.4517 8.2936 3.7085 0.7949
NCI-H1792 GDSC1 6.4572 11.1294 2.4903 8.0716
NCI-H596 GDSC1 6.4584 7.9688 3.8302 0.3758
NCI-H2869 GDSC1 6.4606 9.0089 3.4297 2.1266
NCI-H2171 GDSC1 6.4611 8.0495 3.8023 0.457
NCI-H2122 GDSC1 6.4896 7.9851 3.8362 0.3451
NCI-H2818 GDSC1 6.4974 8.4379 3.6729 0.902
NCI-H748 GDSC1 6.4984 14.9431 0.6977 18.3112
NCI-H1437 GDSC1 6.5044 8.2231 3.7561 0.5828
Calu-6 GDSC1 6.5181 8.4768 3.6669 0.9102
NCI-H2009 GDSC1 6.5216 8.77 3.5547 1.4091
NCI-H2085 GDSC1 6.5245 8.7009 3.5832 1.2717
SW1271 GDSC1 6.5276 8.6602 3.6004 1.1898
NCI-H2342 GDSC1 6.5419 14.2421 1.0679 16.3414
NCI-H2227 GDSC1 6.5554 8.3073 3.7454 0.5877
HCC15 GDSC1 6.5632 8.7484 3.5817 1.2411
NCI-H647 GDSC1 6.5634 9.4384 3.302 2.7049
NCI-H2170 GDSC1 6.5641 8.2563 3.7674 0.5099
NCI-H1666 GDSC1 6.5774 8.5021 3.682 0.8037
NCI-H82 GDSC1 6.5836 8.0256 3.8567 0.2573
NCI-H2291 GDSC1 6.5846 8.4158 3.7171 0.6677
Lu-139 GDSC1 6.6018 8.1684 3.8133 0.3569
EMC-BAC-2 GDSC1 6.6054 8.7075 3.6158 1.0514
EKVX GDSC1 6.6192 9.1507 3.4474 1.8366
LOU-NH91 GDSC1 6.6295 8.6056 3.6646 0.8324
PC-14 GDSC1 6.6362 8.2475 3.7981 0.3825
NCI-H1915 GDSC1 6.637 8.2924 3.7825 0.4262
NCI-H1975 GDSC1 6.6439 8.2601 3.7966 0.3832
HOP-92 GDSC1 6.6541 8.7523 3.6194 0.9952
NCI-H1355 GDSC1 6.6553 8.83 3.5901 1.1185
NCI-H345 GDSC1 6.658 31.3611 -7.3036 36.4047
NCI-H1299 GDSC1 6.6605 9.4079 3.3625 2.2356
NCI-H1688 GDSC1 6.6845 8.6033 3.6879 0.7064
EMC-BAC-1 GDSC1 6.6914 10.4101 2.952 4.6169
Lu-135 GDSC1 6.7055 8.6623 3.6745 0.7407
NCI-H2030 GDSC1 6.7204 8.5019 3.7392 0.5129
NCI-H292 GDSC1 6.7244 9.3566 3.4136 1.8882
NCI-H1944 GDSC1 6.7295 8.9646 3.5702 1.1393
HARA [Human squamous cell lung carcinoma] GDSC1 6.7369 8.9507 3.5787 1.0967
LXF 289 GDSC1 6.737 8.6598 3.6881 0.6714
NCI-H520 GDSC1 6.7808 8.4723 3.7727 0.3867
DMS 114 GDSC1 6.7844 13.4244 1.6229 12.6789
IST-SL1 GDSC1 6.7845 8.5357 3.7516 0.4434
NCI-H2023 GDSC1 6.7876 8.3419 3.8208 0.2669
A-427 GDSC1 6.7941 9.5065 3.3856 1.9508
NCI-H3122 GDSC1 6.7987 8.8133 3.6561 0.7445
NCI-H196 GDSC1 6.8082 13.2966 1.6989 12.1811
HOP-62 GDSC1 6.8088 8.7337 3.6894 0.6226
LCLC-97TM1 GDSC1 6.8157 8.6865 3.7093 0.5541
NCI-H524 GDSC1 6.8337 8.3422 3.8372 0.2184
NCI-H661 GDSC1 6.8394 8.7997 3.6774 0.6445
NCI-H322M GDSC1 6.8402 9.0139 3.5981 0.9335
NCI-H650 GDSC1 6.8705 8.5193 3.7893 0.3091
NCI-H2405 GDSC1 6.8733 11.1887 2.7094 5.8084
NCI-H1838 GDSC1 6.8748 8.706 3.725 0.4758
NCI-H2595 GDSC1 6.8844 8.7419 3.7158 0.498
NCI-H2347 GDSC1 6.8852 8.9819 3.6285 0.7862
NCI-H2135 GDSC1 6.887 8.5785 3.7747 0.3378
SBC-3 GDSC1 6.901 8.657 3.7523 0.3886
EPLC-272H GDSC1 6.932 15.3396 0.8073 16.6714
DMS 273 GDSC1 6.9341 12.696 2.0599 9.735
NCI-H513 GDSC1 6.9632 8.9173 3.683 0.5561
NCI-H2731 GDSC1 6.9698 17.629 -0.2749 21.3111
NCI-H209 GDSC1 6.9808 9.0146 3.6545 0.6365
NCI-H2461 GDSC1 6.9915 8.9785 3.6718 0.5755
NCI-H1650 GDSC1 7.018 9.1462 3.621 0.7262
NCI-H2591 GDSC1 7.0232 9.0721 3.6502 0.6261
NCI-H2228 GDSC1 7.0285 9.0336 3.6662 0.5729
ChaGo-K-1 GDSC1 7.0325 8.9567 3.6953 0.4846
NCI-H1703 GDSC1 7.0641 11.7019 2.589 6.2016
NCI-H441 GDSC1 7.074 8.7906 3.7689 0.2841
NCI-H69 GDSC1 7.1633 16.1137 0.593 17.1334
A-549 GDSC1 7.186 9.1274 3.6924 0.4236
NCI-H1568 GDSC1 7.2712 9.0102 3.7639 0.2354
Lu-134-A GDSC1 7.2985 9.4002 3.6379 0.5206
RERF-LC-KJ GDSC1 7.3389 8.8231 3.8499 0.0964
SW1573 GDSC1 7.344 9.544 3.6037 0.5972
SBC-1 GDSC1 7.3849 26.7397 -4.4479 31.2391
RERF-LC-Sq1 GDSC1 7.5967 10.1595 3.4788 0.8535
NCI-H2110 GDSC1 7.6991 9.6949 3.6813 0.2724
⏷ Show the Full List of 171 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 5.8752 8.556 3.3163 3.7588
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 680N GDSC1 5.5955 7.4918 3.6303 2.2209
T.T GDSC1 5.8458 7.9495 3.5655 2.2171
TE-4 GDSC1 5.9588 8.2348 3.5024 2.4234
OE19 GDSC1 5.9979 7.4172 3.8505 0.5815
TE-9 GDSC1 6.0997 7.668 3.7982 0.7103
KYSE-520 GDSC1 6.1102 11.8833 1.9078 12.672
EC-GI-10 GDSC1 6.1375 8.2001 3.6058 1.5839
KYSE-270 GDSC1 6.2513 9.1637 3.2569 3.4647
KYSE-450 GDSC1 6.2614 7.6804 3.8585 0.3909
OE33 GDSC1 6.3904 9.1118 3.352 2.6655
TE-15 GDSC1 6.4903 9.5559 3.2147 3.3323
KYSE-510 GDSC1 6.5492 7.7828 3.9275 0.1316
TE-11 GDSC1 6.719 8.2275 3.8357 0.2574
TE-8 GDSC1 6.7249 8.8639 3.6068 0.9893
KYSE-180 GDSC1 6.808 8.8187 3.6579 0.7319
TE-6 GDSC1 6.81 8.5755 3.747 0.4441
KYSE-150 GDSC1 6.8296 8.0982 3.918 0.0932
KYSE-410 GDSC1 6.8595 8.7339 3.7091 0.531
KYSE-70 GDSC1 6.8596 8.579 3.7644 0.3746
TE-5 GDSC1 6.9129 8.4489 3.8289 0.212
KYSE-140 GDSC1 6.9151 8.7949 3.7085 0.504
OE21 GDSC1 6.952 8.6777 3.7638 0.339
TE-10 GDSC1 7.0551 9.2467 3.5989 0.7798
TE-1 GDSC1 7.0884 11.0464 2.8892 4.3334
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TYK-nu GDSC1 5.5873 7.3472 3.6882 1.8756
OVCAR-3 GDSC1 5.7339 7.8267 3.5593 2.4357
OV56 GDSC1 5.7828 7.0474 3.9007 0.5471
TOV-21G GDSC1 5.7885 9.5186 2.8206 7.3833
ES-2 GDSC1 5.8518 7.4747 3.7648 1.0959
IGROV-1 GDSC1 5.9798 8.0649 3.5849 1.9054
OAW42 GDSC1 6.0896 12.0567 1.8102 13.331
OV-90 GDSC1 6.2613 8.6369 3.4861 2.0782
DOV13 GDSC1 6.2693 8.4635 3.5611 1.6599
OC 314 GDSC1 6.2905 9.2021 3.2613 3.371
EFO-27 GDSC1 6.4098 8.9278 3.4385 2.1451
OVCAR-4 GDSC1 6.4227 8.2464 3.7142 0.7943
TOV-112D GDSC1 6.4519 8.5076 3.6266 1.1422
Caov-3 GDSC1 6.473 8.2779 3.7232 0.7224
OVCAR-5 GDSC1 6.4962 8.107 3.7951 0.4604
EFO-21 GDSC1 6.4966 8.0789 3.8054 0.4289
OVISE GDSC1 6.5427 7.6491 3.9699 0.076
OVTOKO GDSC1 6.6721 8.7462 3.6293 0.9399
JHOS-2 GDSC1 6.7086 8.131 3.8652 0.2002
OVK18 GDSC1 6.7924 8.134 3.8934 0.1324
A2780 GDSC1 6.841 10.0198 3.1976 2.9084
RMG-I GDSC1 6.8431 9.7371 3.3152 2.2593
SK-OV-3 GDSC1 6.9412 8.5333 3.81 0.2406
FU-OV-1 GDSC1 6.9607 8.5051 3.8265 0.2034
OVCAR-8 GDSC1 7.0162 8.4476 3.8652 0.1292
Kuramochi GDSC1 7.2447 8.9976 3.7588 0.2525
OVKATE GDSC1 7.2543 8.7327 3.8512 0.107
Caov-4 GDSC1 7.3737 9.2468 3.7192 0.293
OAW28 GDSC1 7.4597 9.4447 3.6818 0.3449
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MZ-PC-1 GDSC1 2.2821 14.6286 -2.6165 41.7039
HPAC GDSC1 4.3114 10.7248 1.1117 23.0667
PaTu 8988t GDSC1 5.4706 9.1153 2.8018 8.3286
KP-4 GDSC1 5.5655 8.9584 2.9401 7.083
SU.86.86 GDSC1 5.6411 7.3959 3.6953 1.7508
KP-2 GDSC1 5.8343 7.5837 3.7126 1.3878
QGP-1 GDSC1 5.8923 8.3436 3.4199 3.0501
HPAF-II GDSC1 5.9316 9.9325 2.7179 7.7551
Capan-1 GDSC1 5.9951 7.729 3.729 1.1178
BxPC-3 GDSC1 6.0161 8.1467 3.5688 1.9468
DAN-G GDSC1 6.0988 7.8045 3.7455 0.937
PaTu 8902 GDSC1 6.2111 7.7791 3.8024 0.6105
SW1990 GDSC1 6.2835 8.8692 3.4 2.5416
SUIT-2 GDSC1 6.3673 7.7956 3.8575 0.3422
MIA PaCa-2 GDSC1 6.388 7.8379 3.8503 0.3525
CFPAC-1 GDSC1 6.396 7.8507 3.8487 0.3532
Panc 08.13 GDSC1 6.4436 9.3271 3.2881 2.9638
Hs 766T GDSC1 6.4761 8.2273 3.7432 0.6462
Panc 04.03 GDSC1 6.4908 11.2581 2.4516 8.2497
Panc 03.27 GDSC1 6.516 11.7151 2.2547 9.4642
PL4 GDSC1 6.5168 8.2308 3.7581 0.5681
Panc 10.05 GDSC1 6.5579 8.2659 3.7615 0.5325
YAPC GDSC1 6.5969 7.8527 3.9205 0.1322
PSN1 GDSC1 6.7457 12.042 2.2462 8.9979
HuP-T3 GDSC1 6.7694 8.2781 3.8363 0.2396
HuP-T4 GDSC1 6.8241 8.8617 3.6485 0.755
KP-3 GDSC1 7.0357 9.3727 3.544 0.9977
Panc 02.03 GDSC1 7.3229 8.992 3.7881 0.181
Capan-2 GDSC1 7.4833 9.3861 3.7105 0.2776
AsPC-1 GDSC1 7.497 9.5903 3.6447 0.4176
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1 5.8138 8.2406 3.4218 3.178
NCI-H2452 GDSC1 6.2646 8.9102 3.373 2.7303
IST-Mes1 GDSC1 6.3108 8.4228 3.5968 1.4287
NCI-H28 GDSC1 6.3882 8.11 3.7512 0.6771
MSTO-211H GDSC1 6.4547 8.6559 3.5697 1.407
NCI-H2052 GDSC1 7.0309 8.9143 3.7098 0.445
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1 6.106 9.669 2.9483 5.775
VCaP GDSC1 6.2809 7.9792 3.7561 0.7373
DU145 GDSC1 6.6961 9.7947 3.2192 2.9914
PC-3 GDSC1 7.1862 9.1737 3.6761 0.4668
22Rv1 GDSC1 7.228 8.9978 3.7528 0.2692
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 6.3268 8.6831 3.499 1.9211
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-MEL-30 GDSC1 4.8083 6.801 3.4607 5.2192
SK-MEL-28 GDSC1 4.9368 6.2817 3.7948 2.3872
SK-MEL-2 GDSC1 5.0698 6.3295 3.8516 1.7204
G-361 GDSC1 5.2867 7.0855 3.6373 2.7451
UACC-62 GDSC1 5.3963 7.2229 3.6387 2.5214
SK-MEL-3 GDSC1 5.5537 7.2194 3.7253 1.7034
GAK GDSC1 5.641 7.4114 3.6886 1.7905
VMRC-MELG GDSC1 5.7436 7.6005 3.661 1.8015
LB373-MEL-D GDSC1 5.7578 7.284 3.7978 1.0346
COLO 783 GDSC1 5.797 7.346 3.7911 1.0254
IPC-298 GDSC1 5.8147 7.2953 3.819 0.8726
A2058 GDSC1 5.8419 7.2367 3.8536 0.6929
COLO 800 GDSC1 5.8451 9.4849 2.8725 6.8827
UACC-257 GDSC1 5.8866 9.346 2.9633 6.1526
WM115 GDSC1 5.89 8.8142 3.2089 4.4516
MeWo GDSC1 5.9265 9.826 2.7646 7.4429
IGR-37 GDSC1 5.93 7.3919 3.8317 0.7106
Mel JuSo GDSC1 5.9534 8.0993 3.5571 2.1041
Hs 940.T GDSC1 5.9534 7.7724 3.6923 1.3501
WM278 GDSC1 5.983 8.1377 3.556 2.0679
CP66-MEL GDSC1 6.0399 7.4404 3.859 0.5206
LB2518-MEL GDSC1 6.0405 7.5614 3.8138 0.694
SK-MEL-5 GDSC1 6.0411 8.2959 3.5188 2.2009
WT2-iPS GDSC1 6.0489 7.442 3.862 0.5037
A101D GDSC1 6.109 7.2236 3.9629 0.1845
LOX-IMVI GDSC1 6.1275 8.0592 3.6579 1.3261
RVH-421 GDSC1 6.1303 7.7541 3.7784 0.7667
SK-MEL-1 GDSC1 6.1613 7.5515 3.8663 0.4206
MMAc-SF GDSC1 6.1656 7.6631 3.8271 0.5515
MZ-MEL-7 GDSC1 6.1732 7.7755 3.7882 0.6928
HT-144 GDSC1 6.1861 7.8695 3.758 0.8054
MZ-MEL-2 GDSC1 6.2051 12.57 1.6423 14.034
SH-4 GDSC1 6.2063 8.2656 3.6116 1.4718
Hs 938.T GDSC1 6.2113 7.45 3.9214 0.2427
CP50-MEL-B GDSC1 6.3225 7.6412 3.8953 0.2629
SK-MEL-24 GDSC1 6.3269 7.8467 3.8237 0.4637
451Lu GDSC1 6.3306 8.1423 3.7151 0.8644
COLO 679 GDSC1 6.3309 8.0981 3.732 0.7949
IST-MEL1 GDSC1 6.3697 9.1986 3.3046 2.9787
COLO 792 GDSC1 6.4166 9.2757 3.296 2.9578
COLO 829 GDSC1 6.457 8.0953 3.7841 0.5173
CHL-1 GDSC1 6.4625 8.4001 3.6726 0.9323
G-mel GDSC1 6.4759 8.3024 3.7151 0.7509
DJM-1 GDSC1 6.49 8.3812 3.6913 0.8335
Mel Ho GDSC1 6.4982 7.9025 3.8684 0.261
A-431 GDSC1 6.5906 11.1481 2.563 7.3076
A-375 GDSC1 6.608 8.209 3.8012 0.3869
RPMI-7951 GDSC1 6.6525 8.176 3.8294 0.2956
WM1552C GDSC1 6.6713 8.356 3.7728 0.4373
IGR-1 GDSC1 6.7263 8.0241 3.9075 0.1249
M14 GDSC1 6.7463 8.2054 3.8531 0.2128
A-388 GDSC1 6.7573 8.7964 3.6456 0.8117
HMV-II GDSC1 6.7812 9.0033 3.5774 1.0644
WM793 GDSC1 6.7919 8.216 3.8655 0.1773
WM35 GDSC1 6.827 8.5979 3.7455 0.4404
EquiPSC Line K2 GDSC1 6.4493 9.2044 3.3428 2.6335
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 5.0886 8.5857 2.7903 9.4893
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW684 GDSC1 5.4138 7.2252 3.6476 2.4299
KYM-1 GDSC1 5.8142 10.2621 2.4846 9.6625
SK-UT-1 GDSC1 5.8529 7.9085 3.5865 2.0798
MFH-ino GDSC1 5.9727 7.8799 3.6578 1.5095
SW982 GDSC1 6.0562 7.6133 3.8007 0.7352
VA-ES-BJ GDSC1 6.077 7.5757 3.8236 0.6268
MES-SA GDSC1 6.1278 7.2909 3.9464 0.2148
GCT GDSC1 6.2969 8.209 3.6748 1.0701
RKN GDSC1 6.3041 9.2707 3.2389 3.4881
TE 441.T GDSC1 6.4096 7.7188 3.9 0.2208
Hs 633.T GDSC1 6.468 7.7774 3.9008 0.2006
RD GDSC1 6.5095 8.5428 3.638 1.0396
Rh30 GDSC1 6.5528 8.6525 3.6143 1.1042
HT-1080 GDSC1 6.5793 8.1297 3.8186 0.3527
Rh41 GDSC1 6.7841 8.3466 3.8179 0.2745
SK-LMS-1 GDSC1 6.8228 8.559 3.7577 0.4085
EW-8 GDSC1 6.8268 8.5139 3.7751 0.3608
G-401 GDSC1 6.8568 9.5703 3.3891 1.8619
SW872 GDSC1 7.0759 8.7208 3.7936 0.2334
A-204 GDSC1 7.2159 9.6762 3.5043 1.0171
G-402 GDSC1 7.6361 9.6219 3.684 0.285
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 746.T GDSC1 4.7875 6.6396 3.5244 4.7902
NUGC-4 GDSC1 5.4423 9.3439 2.6722 9.3394
MKN45 GDSC1 5.5061 6.7382 3.9003 0.8007
TMK-1 GDSC1 5.5695 8.3089 3.2474 4.8699
SNU-16 GDSC1 5.6421 7.2236 3.7677 1.3334
NCI-N87 GDSC1 5.6537 9.2414 2.8639 7.4086
Fu97 GDSC1 5.7092 8.3195 3.3267 4.0164
IM95 GDSC1 5.7728 8.3706 3.3407 3.7939
AGS GDSC1 5.8436 8.8222 3.1779 4.7597
SCH GDSC1 5.8659 7.3509 3.8199 0.819
23132/87 GDSC1 5.9417 7.537 3.7807 0.9261
HGC-27 GDSC1 5.9669 8.5423 3.3736 3.2155
SNU-1 GDSC1 6.0323 8.2153 3.5482 2.0419
OCUM-1 GDSC1 6.0325 8.4315 3.4568 2.5853
ECC10 GDSC1 6.2943 8.233 3.6644 1.1206
MKN7 GDSC1 6.5056 14.8348 0.7554 18.0129
NUGC-3 GDSC1 6.5607 8.6557 3.6165 1.0877
GCIY GDSC1 6.5726 8.7308 3.5926 1.1826
MKN1 GDSC1 6.6646 8.5652 3.694 0.6975
RF-48 GDSC1 6.6759 8.4383 3.7449 0.5191
SNU-5 GDSC1 6.7267 8.2003 3.8478 0.2292
RERF-GC-1B GDSC1 6.7931 9.67 3.3188 2.3029
TGBC11TKB GDSC1 6.805 8.7674 3.6756 0.6717
HSC-39 GDSC1 6.9061 8.3457 3.8615 0.1571
MKN28 GDSC1 7.4114 9.3797 3.6869 0.3504
SNG-M GDSC1 6.0186 10.4862 2.5131 8.9489
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
B-CPAP GDSC1 5.2878 7.0514 3.6533 2.6337
IHH-4 GDSC1 5.3916 8.4629 3.0607 6.648
TT GDSC1 5.6502 7.5994 3.613 2.2386
WRO GDSC1 5.6956 7.3428 3.7446 1.3912
KMH-2 GDSC1 5.7804 12.6144 1.3194 17.0776
CGTH-W-1 GDSC1 5.8165 7.4045 3.7767 1.0756
FTC-133 GDSC1 5.8607 7.6211 3.71 1.3692
ASH-3 GDSC1 6.0039 7.4384 3.845 0.5982
CAL-62 GDSC1 6.0742 8.2024 3.5743 1.8361
HTC-C3 GDSC1 6.2051 8.722 3.4223 2.5269
BHT-101 GDSC1 6.2103 8.038 3.7035 1.022
ML-1 [Human leukemia] GDSC1 6.2344 8.4193 3.5625 1.6948
TT2609-C02 GDSC1 6.4884 8.3903 3.6872 0.8512
8305C GDSC1 6.5117 8.0682 3.815 0.3936
K5 GDSC1 6.5186 8.3522 3.714 0.7243
8505C GDSC1 6.7539 8.5691 3.7278 0.5299
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-9 GDSC1 5.3858 7.5923 3.4653 3.7347
BHY GDSC1 5.6334 8.0034 3.4252 3.4985
SCC-25 GDSC1 5.8102 7.9135 3.5623 2.2927
HSC-2 GDSC1 5.8114 7.5219 3.7269 1.3396
PCI-15A GDSC1 5.8318 7.64 3.6883 1.5236
SAS GDSC1 5.9936 8.1259 3.5662 1.9929
Detroit 562 GDSC1 6.0474 8.1227 3.5941 1.7614
CAL-27 GDSC1 6.0535 7.5386 3.8279 0.6279
BB49-HNC GDSC1 6.1974 8.7071 3.4247 2.5242
HO-1-N-1 GDSC1 6.2132 7.9804 3.727 0.9145
OSC-20 GDSC1 6.2159 9.2268 3.2101 3.8237
BB30-HNC GDSC1 6.2267 8.0005 3.7251 0.911
PCI-30 GDSC1 6.2724 7.7503 3.8374 0.4504
HSC-3 GDSC1 6.292 7.992 3.7559 0.7298
BICR 31 GDSC1 6.2937 8.2179 3.67 1.0953
LB771-HNC GDSC1 6.3473 9.4682 3.1762 3.8082
HO-1-u-1 GDSC1 6.3915 8.2127 3.714 0.8197
CAL-33 GDSC1 6.4055 8.1164 3.7558 0.648
SKN-3 GDSC1 6.4268 8.5807 3.5868 1.3532
HSC-4 GDSC1 6.489 8.0857 3.8 0.4492
SCC-4 GDSC1 6.5036 8.5758 3.6227 1.1118
PE/CA-PJ15 GDSC1 6.5122 8.2113 3.7635 0.553
BICR 22 GDSC1 6.5274 8.1515 3.7911 0.4562
BICR 78 GDSC1 6.6156 8.635 3.6478 0.9098
DOK GDSC1 6.6471 8.7807 3.6056 1.0592
OSC-19 GDSC1 6.648 8.5776 3.6827 0.7502
KON GDSC1 6.6629 8.4034 3.7525 0.5026
JHU-011 GDSC1 6.6891 8.5334 3.7155 0.6072
PCI-38 GDSC1 6.7134 8.6098 3.6971 0.655
JHU-022 GDSC1 6.7458 8.5277 3.7396 0.498
FaDu GDSC1 6.7951 8.1005 3.9055 0.1147
BICR 10 GDSC1 6.9595 8.5993 3.7938 0.2683
SCC-15 GDSC1 6.9805 8.9988 3.6602 0.6183
SAT [Human HNSCC] GDSC1 7.0073 9.9043 3.3247 2.0159
PCI-04B GDSC1 7.1514 9.1773 3.6617 0.5235
PCI-06A GDSC1 7.1881 8.8984 3.7726 0.2419
Ca9-22 GDSC1 7.2645 9.1145 3.7256 0.3147
KOSC-2 GDSC1 7.4175 9.3406 3.7026 0.3139
NCI-H3118 GDSC1 7.505 9.6181 3.6379 0.4311
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
639V GDSC1 5.4855 6.775 3.8761 0.9463
KU-19-19 GDSC1 5.5322 6.8094 3.8839 0.8537
5637 GDSC1 5.6616 8.2525 3.329 4.0991
647V GDSC1 5.801 8.046 3.5002 2.6958
BFTC-905 GDSC1 5.8335 7.682 3.6718 1.6134
HT-1376 GDSC1 6.0235 8.009 3.6293 1.5994
RT-4 GDSC1 6.0342 8.2593 3.5307 2.1409
UM-UC-3 GDSC1 6.1879 8.8705 3.3499 2.9911
CAL-29 GDSC1 6.2594 7.8859 3.7823 0.6519
SW780 GDSC1 6.2951 8.1589 3.6935 0.9879
HT-1197 GDSC1 6.2963 9.845 2.9806 5.1694
SW1710 GDSC1 6.431 8.1704 3.7461 0.6663
TCCSUP GDSC1 6.5339 7.9098 3.8788 0.2255
RT-112 GDSC1 6.548 8.2031 3.7805 0.4778
J82 GDSC1 7.1148 8.6778 3.8219 0.1736
T24 GDSC1 7.5172 9.2968 3.7527 0.194
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NEC8 GDSC1 5.2642 7.669 3.3534 4.8204
JAR GDSC1 5.5751 8.5499 3.1387 5.6315
HeLa GDSC1 5.6108 6.9785 3.8524 0.924
DSH1 GDSC1 5.6123 9.6706 2.6315 9.1688
SW756 GDSC1 5.617 7.6401 3.5773 2.5213
OMC-1 [Human cervical carcinoma] GDSC1 5.7184 8.5174 3.2421 4.5806
Ca Ski GDSC1 5.7932 9.4164 2.8716 7.0128
SiHa GDSC1 5.8319 7.4418 3.7688 1.0978
HEC-1 GDSC1 5.8456 7.2547 3.8483 0.7125
PEO1 GDSC1 5.8787 9.5566 2.8603 6.8895
PA-1 GDSC1 5.9774 8.3115 3.4793 2.535
SKN GDSC1 5.9803 9.4604 2.968 5.9111
OVCA433 GDSC1 6.0175 7.9712 3.6419 1.5389
JEG-3 GDSC1 6.033 7.8427 3.701 1.2147
C-33 A GDSC1 6.0746 8.2989 3.5343 2.0621
DoTc2 4510 GDSC1 6.1035 7.9648 3.6846 1.2196
OV17R GDSC1 6.1296 8.4308 3.5067 2.1434
SW954 GDSC1 6.1663 8.4708 3.5083 2.083
ACC-OV7 GDSC1 6.1752 8.913 3.3249 3.1675
C-4-I GDSC1 6.2 8.3221 3.5857 1.6138
UWB1.289 GDSC1 6.2263 8.714 3.4364 2.4122
SKG-IIIa GDSC1 6.239 7.8975 3.7695 0.7164
OVCA420 GDSC1 6.3043 8.4364 3.5884 1.4782
BPH-1 GDSC1 6.3813 10.9558 2.5238 8.0218
NCC-IT GDSC1 6.4899 7.9033 3.8651 0.2718
MS751 GDSC1 6.496 8.3008 3.724 0.7029
HEY GDSC1 6.6016 8.5833 3.6614 0.8661
LB831-BLC GDSC1 6.6487 8.4643 3.7248 0.6004
ME-180 GDSC1 6.7201 9.1249 3.5037 1.4488
SW962 GDSC1 6.7355 8.443 3.7661 0.4255
NT2-D1 GDSC1 6.952 8.5918 3.7937 0.2711
JHOS-3 GDSC1 7.0096 10.4208 3.1141 3.1438
HT-3 GDSC1 7.0188 8.7307 3.7698 0.3009
CAL-39 GDSC1 7.0519 8.9075 3.7201 0.4085
KGN GDSC1 7.337 9.537 3.6036 0.6012
SiSo GDSC1 7.3716 9.2891 3.7039 0.3262
OVMIU GDSC1 7.4457 10.1358 3.4265 1.1472
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16078-83.