Details of the Drug

General Information of Drug (ID: DMTXWCZ)

Drug Name
LFM-A13
Synonyms
lfm-a13; 244240-24-2; (Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide; SMR001230714; SR-01000075965; 62004-35-7; C11H8Br2N2O2; 2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide; BiomolKI_000050; LFMA13; BiomolKI2_000056; AC1L1H0E; AC1NS4I5; Lopac0_000650; SCHEMBL51142; BSPBio_001239; BMK1-F2; MLS006010694; MLS002153290; GTPL9262; CHEBI:95065; 2-cyano-N-(2,5-dibromophenyl); MolPort-003-958-579; HMS1362M21; HMS3403M21; HMS2235P16; HMS1990M21; HMS1792M21; BCP12817; 3781AH; s7734; BS0111; ZINC37868487; AKOS024456516; CS-3890
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 360
Logarithm of the Partition Coefficient (xlogp) 3.8
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C11H8Br2N2O2
IUPAC Name
(Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide
Canonical SMILES
C/C(=C(\\C#N)/C(=O)NC1=C(C=CC(=C1)Br)Br)/O
InChI
InChI=1S/C11H8Br2N2O2/c1-6(16)8(5-14)11(17)15-10-4-7(12)2-3-9(10)13/h2-4,16H,1H3,(H,15,17)/b8-6-
InChIKey
UVSVTDVJQAJIFG-VURMDHGXSA-N
Cross-matching ID
PubChem CID
54676905
ChEBI ID
CHEBI:95065
TTD ID
D08NTB

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tyrosine-protein kinase BTK (ATK) TTGM6VW BTK_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tyrosine-protein kinase BTK (ATK) DTT BTK 3.54E-01 0.24 0.56
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 6.5486 14.0696 0.8981 14.7086
MHH-ES-1 GDSC1 1.723 15.8688 -3.9246 43.5516
ES7 GDSC1 4.2625 8.68 1.875 15.4235
HuO-3N1 GDSC1 4.3359 6.9653 2.7871 8.4019
HOS GDSC1 4.6509 5.9488 3.4998 2.1183
EW-7 GDSC1 4.6568 11.132 0.9655 19.7548
ES8 GDSC1 4.7034 6.8764 3.0974 4.9363
A-673 GDSC1 4.7937 6.5933 3.29 3.2929
ES6 GDSC1 4.892 7.1438 3.0948 4.4788
SK-PN-DW GDSC1 4.9494 8.7591 2.3578 9.7673
CAL-78 GDSC1 5.0674 6.9323 3.2989 2.6544
G-292 clone A141B1 GDSC1 5.0951 7.0642 3.2556 2.8927
EW-13 GDSC1 5.2905 12.7993 0.6241 19.5722
EW-3 GDSC1 5.3634 7.4664 3.2279 2.579
EW-1 GDSC1 5.5533 11.1739 1.6106 13.1521
MG-63 GDSC1 5.5634 10.6545 1.8683 11.4592
NY GDSC1 5.6287 8.4615 2.9359 4.0031
ES4 GDSC1 5.6723 8.4532 2.9643 3.7337
CAL-72 GDSC1 5.7894 7.6431 3.3661 1.1942
EW-24 GDSC1 5.8401 7.1748 3.5645 0.3585
TC-71 GDSC1 5.9405 7.7331 3.3975 0.904
ES1 GDSC1 5.9794 8.8046 2.9777 3.1167
CHSA8926 GDSC1 6.0563 7.7617 3.435 0.6627
CHSA0108 GDSC1 6.0987 8.789 3.0457 2.5311
NOS-1 [Human HNSCC] GDSC1 6.21 8.7343 3.1227 1.9561
ES5 GDSC1 6.231 10.8896 2.1892 7.725
H-EMC-SS GDSC1 6.2438 8.9618 3.0456 2.3312
EW-16 GDSC1 6.2447 16.2117 -0.3512 21.3555
EW-18 GDSC1 6.2894 11.2282 2.0689 8.3751
EW-11 GDSC1 6.3084 14.485 0.5343 17.1911
HuO9 GDSC1 6.8925 9.0091 3.3087 0.5834
SK-ES-1 GDSC1 6.937 18.2251 -0.8384 21.5263
CHSA0011 GDSC1 7.004 9.2618 3.2605 0.6722
U2OS GDSC1 7.6087 19.2602 -0.8724 20.1188
SJSA-1 GDSC1 7.6924 19.3781 -0.872 19.9343
SaOS-2 GDSC1 8.2001 20.0759 -0.8647 18.8321
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 153 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 7.0762 14.1746 1.1907 11.8897
KE-37 GDSC1 4.7524 7.4351 2.8619 6.5779
A4/Fukuda GDSC1 4.7528 11.4928 0.861 20.0115
Karpas-231 GDSC1 4.8506 13.0391 0.1683 23.1327
P32/ISH GDSC1 4.8589 11.3048 1.0364 18.6937
SR GDSC1 4.881 12.1186 0.6495 20.7127
SIG-M5 GDSC1 4.9305 9.4448 2.0088 12.3082
NB4 GDSC1 4.9418 11.6245 0.9414 18.9612
Ku812 GDSC1 4.9734 15.9877 -1.2032 27.97
IM-9 GDSC1 4.9832 6.8535 3.2855 2.9135
CTV-1 GDSC1 5.0112 7.9638 2.7843 6.4641
SU-DHL-8 GDSC1 5.0213 10.3473 1.6321 14.562
Daudi GDSC1 5.0282 8.0029 2.7769 6.4747
OPM-2 GDSC1 5.0508 7.7964 2.8899 5.5895
SUP-B15 GDSC1 5.1014 8.2128 2.7256 6.6631
YT GDSC1 5.1171 7.1012 3.2517 2.876
Raji GDSC1 5.1292 6.5942 3.4792 1.4069
JURL-MK1 GDSC1 5.1304 6.9995 3.3046 2.4977
697 GDSC1 5.1353 8.4569 2.6319 7.2596
WIL2 NS GDSC1 5.1586 8.6669 2.5472 7.8149
QIMR-WIL GDSC1 5.1884 8.5107 2.6416 7.053
Farage GDSC1 5.2003 7.5057 3.1176 3.6251
KOPN-8 GDSC1 5.2216 8.3574 2.7358 6.289
MOLT-16 GDSC1 5.2324 7.1368 3.3005 2.3412
A3/Kawakami GDSC1 5.2376 9.3345 2.2804 9.517
DEL GDSC1 5.2383 8.7698 2.5514 7.5774
MV4-11 GDSC1 5.269 8.6936 2.6078 7.0939
SU-DHL-1 GDSC1 5.2883 6.4974 3.5927 0.6319
LC4-1 GDSC1 5.2883 9.8676 2.0581 10.9303
DoHH2 GDSC1 5.2991 6.8993 3.4364 1.4138
PF-382 GDSC1 5.3129 7.8316 3.0363 3.9531
HEL GDSC1 5.3153 9.4117 2.2963 9.1962
CCRF-CEM GDSC1 5.3213 10.054 1.9909 11.2981
ST486 GDSC1 5.3407 7.8912 3.0256 3.9689
BALL-1 GDSC1 5.372 6.9467 3.4523 1.2318
MOLT-4 GDSC1 5.3864 8.5792 2.7368 5.8898
Karpas-45 GDSC1 5.3997 9.9332 2.1033 10.3153
OCI-Ly19 GDSC1 5.4071 10.957 1.613 13.5469
BL-41 GDSC1 5.4129 6.8357 3.5156 0.8651
P31/FUJ GDSC1 5.4281 6.4712 3.6594 0.286
HC-1 GDSC1 5.4433 7.9265 3.0691 3.4716
L-428 GDSC1 5.451 7.4813 3.2681 2.1821
P12-Ichikawa GDSC1 5.4541 6.991 3.4727 1.0304
ATN-1 GDSC1 5.458 7.2324 3.3764 1.5364
L-363 GDSC1 5.466 7.2367 3.3786 1.5137
VL51 GDSC1 5.4966 8.9185 2.6479 6.2621
MC116 GDSC1 5.499 6.428 3.7009 0.1503
TK [Human B-cell lymphoma] GDSC1 5.5169 7.72 3.2002 2.4944
Ramos.2G6.4C10 GDSC1 5.5235 7.5416 3.2798 2.0005
SUP-T1 GDSC1 5.5342 8.4843 2.8707 4.6325
CESS GDSC1 5.5406 11.1302 1.6229 13.1095
NK-92MI GDSC1 5.5432 9.7483 2.2878 8.6679
WSU-NHL GDSC1 5.5633 8.2066 3.0124 3.6207
Jiyoye GDSC1 5.5662 8.0721 3.0735 3.2152
DB GDSC1 5.5669 9.6848 2.3334 8.293
SUP-M2 GDSC1 5.5706 6.767 3.6076 0.37
ML-2 GDSC1 5.5787 9.6348 2.3646 8.0474
OCI-AML-5 GDSC1 5.5907 10.5732 1.9259 11.0049
HT GDSC1 5.5974 7.0963 3.4951 0.7831
P30/OHK GDSC1 5.6012 10.1951 2.1138 9.7149
HDLM-2 GDSC1 5.6056 9.4437 2.4715 7.2401
SU-DHL-6 GDSC1 5.6103 11.0267 1.7212 12.2912
KCL-22 GDSC1 5.6268 7.6455 3.2882 1.8047
Reh GDSC1 5.6345 11.686 1.4193 14.1148
OCI-AML-2 GDSC1 5.6415 6.9901 3.5538 0.5114
Karpas-620 GDSC1 5.6914 10.8528 1.8601 11.174
EoL-1 GDSC1 5.6933 8.1605 3.1038 2.804
U266B1 GDSC1 5.7022 7.5949 3.3452 1.3975
KMOE-2 GDSC1 5.7329 9.3113 2.6119 5.9833
MN-60 GDSC1 5.7365 8.2941 3.0691 2.9489
Karpas-299 GDSC1 5.737 7.2642 3.4903 0.6859
HL-60 GDSC1 5.8101 7.0029 3.6141 0.2377
SU-DHL-16 GDSC1 5.8398 9.7355 2.4819 6.6352
MOLM-13 GDSC1 5.8437 9.9008 2.4079 7.1283
KMS-12-BM GDSC1 5.8495 7.6685 3.383 1.0529
Sc-1 GDSC1 5.8556 9.9225 2.4052 7.1197
CTB-1 GDSC1 5.859 10.6539 2.0654 9.3962
NALM-6 GDSC1 5.8773 10.0823 2.3446 7.4809
EM-2 GDSC1 5.9276 7.8007 3.3658 1.0563
JSC-1 GDSC1 5.9424 8.3555 3.1489 2.1605
EHEB GDSC1 5.9432 9.0513 2.8509 3.9748
LAMA-84 GDSC1 5.9448 8.6045 3.0453 2.7617
ALL-PO GDSC1 5.9609 13.2681 0.881 16.3104
PL-21 GDSC1 5.9627 11.742 1.6172 12.0237
KY821 GDSC1 5.9663 7.2952 3.5692 0.2873
OCI-M1 GDSC1 5.9765 7.1949 3.6078 0.1936
SCC-3 GDSC1 5.9791 7.0802 3.6478 0.1196
HAL-01 GDSC1 5.9855 8.6641 3.0409 2.7257
BV-173 GDSC1 5.987 8.0081 3.3108 1.2547
MLMA GDSC1 5.9873 8.9871 2.9031 3.5664
TUR GDSC1 5.9874 7.4411 3.5252 0.4003
JVM-2 GDSC1 5.994 8.5389 3.098 2.379
RPMI-8402 GDSC1 6.015 7.9554 3.3439 1.0732
MHH-PREB-1 GDSC1 6.0187 7.6083 3.4767 0.5388
BC-1 GDSC1 6.0265 11.9877 1.5426 12.3213
EB2 GDSC1 6.0429 8.0825 3.3066 1.2182
H9 GDSC1 6.054 8.2798 3.2332 1.5655
Mono-Mac-6 GDSC1 6.0548 12.6668 1.2364 14.0732
BE-13 GDSC1 6.0927 8.0716 3.3327 1.0514
SK-MM-2 GDSC1 6.1092 8.1207 3.3209 1.089
RL GDSC1 6.1124 7.5161 3.5456 0.2874
Karpas-422 GDSC1 6.1412 7.5628 3.5398 0.2902
Namalwa GDSC1 6.1617 8.1509 3.3318 0.9941
MEG-01 GDSC1 6.2422 8.8378 3.0958 2.0596
ALL-SIL GDSC1 6.2541 17.1546 -0.8063 23.0915
ARH-77 GDSC1 6.2681 11.54 1.9109 9.4331
L-1236 GDSC1 6.2709 8.5069 3.2414 1.2967
U-698-M GDSC1 6.2713 12.7749 1.3305 12.9754
ME1 GDSC1 6.2777 12.8742 1.2874 13.2103
BC-3 GDSC1 6.2781 7.8789 3.4792 0.3908
L-540 GDSC1 6.2857 8.4242 3.28 1.1094
GR-ST GDSC1 6.2981 9.5673 2.8178 3.5793
VAL GDSC1 6.3295 15.5466 0.0341 19.4935
JJN-3 GDSC1 6.3349 8.0235 3.4491 0.4496
NKM-1 GDSC1 6.3405 9.9428 2.6779 4.369
KM-H2 GDSC1 6.352 8.1245 3.4193 0.532
RC-K8 GDSC1 6.3604 7.7535 3.5529 0.1892
DG-75 GDSC1 6.3777 8.629 3.2407 1.1995
RPMI-8866 GDSC1 6.3923 8.1766 3.416 0.5199
Granta-519 GDSC1 6.413 7.8585 3.5356 0.2073
CA46 GDSC1 6.4133 12.4299 1.5865 11.1081
ROS-50 GDSC1 6.4184 9.459 2.9252 2.7684
SUP-HD1 GDSC1 6.4385 9.2139 3.036 2.1351
Hs 445 GDSC1 6.4442 7.9387 3.5193 0.2306
K-562 GDSC1 6.4668 7.8406 3.5606 0.1497
BL-70 CTRP1 6.714 11.1252 3.6494 12.1828
RS4;11 GDSC1 6.7154 15.5278 0.3121 17.2464
KG-1 GDSC1 6.7211 8.4848 3.4302 0.3326
JVM-3 GDSC1 6.7507 8.3742 3.479 0.2206
MY-M12 GDSC1 6.805 16.7783 -0.2294 19.4429
NU-DUL-1 GDSC1; CTRP1 6.877 8.3597 6.7699 13.656
HH [Human lymphoma] GDSC1 6.999 19.1306 -1.235 22.7842
DND-41 GDSC1 7.2281 17.8317 -0.4456 19.3315
LP-1 GDSC1; CTRP1 7.7977 11.4877 6.4055 12.5272
SU-DHL-5 GDSC1; CTRP1 7.8102 11.07 6.6212 11.4314
THP-1 GDSC1; CTRP1 7.8673 8.8882 7.6859 6.1043
RPMI-6666 GDSC1 7.8738 26.9007 -4.4043 29.0203
SKM-1 CTRP1 7.9504 8.4375 7.9204 8.5416
MOLP-8 GDSC1 7.9556 24.7347 -3.2842 26.4947
WSU-DLCL2 GDSC1; CTRP1 8.0272 8.4292 8.0055 4.1238
GDM-1 GDSC1; CTRP1 8.0343 9.4334 7.6208 5.8906
EJM GDSC1; CTRP1 8.1725 8.9775 7.9679 3.8036
PL21 CTRP1 8.1804 8.9023 8.0092 6.415
RPMI-8226 GDSC1; CTRP1 8.1947 9.8101 7.5944 5.5688
AMO1 GDSC1; CTRP1 8.3344 9.0899 8.0755 2.806
OCI-AML-3 GDSC1; CTRP1 8.8127 14.2506 5.9037 12.4915
Loucy GDSC1 8.827 24.7517 -2.6807 23.3082
NOMO-1 GDSC1; CTRP1 9.0651 14.6384 5.9115 11.8991
KMS-11 CTRP1 9.3796 17.7982 4.5855 25.5837
U-937 CTRP1 9.7495 15.591 5.9592 16.932
SU-DHL-4 GDSC1; CTRP1 9.9245 11.1589 8.1203 0.3615
MOLM-16 CTRP1 9.9649 11.8673 7.8536 2.1642
OCI-Ly10 CTRP1 10.6351 15.364 6.6698 9.3805
⏷ Show the Full List of 153 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC1 5.4445 7.7345 3.1548 2.9063
KYSE-50 GDSC1 5.5096 8.4762 2.8597 4.759
HCE-4 GDSC1 6.3344 8.2241 3.3758 0.6896
TE-12 GDSC1 6.5806 11.6743 2.0406 7.9311
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 6.3855 10.6128 2.4064 6.0043
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-6 GDSC1 3.6479 10.2818 0.5611 25.5403
SK-N-DZ GDSC1 4.2341 9.5446 1.4203 18.5284
SJNB-7 GDSC1 4.5018 6.1918 3.2888 4.0309
SK-N-AS GDSC1 4.7239 6.2618 3.4003 2.6614
NB69 GDSC1 5.0584 8.0103 2.7935 6.2759
NH-12 GDSC1 5.1595 7.7292 2.9903 4.6076
SJNB-13 GDSC1 5.371 7.6483 3.152 3.0583
Kelly GDSC1 5.3822 8.3814 2.826 5.2699
SiMa GDSC1 5.4459 7.6431 3.1955 2.6428
IMR-5 GDSC1 5.5181 9.1633 2.5473 6.9179
KP-N-YS GDSC1 5.555 9.8767 2.2346 9.0058
SK-N-MC-IXC GDSC1 5.6052 7.1589 3.4742 0.8691
CHP-126 GDSC1 5.6487 11.4142 1.5607 13.2043
LA-N-6 GDSC1 5.6612 8.2472 3.0488 3.2054
NB1 GDSC1 5.7643 10.5174 2.0683 9.6104
TGW GDSC1 5.975 7.2904 3.5741 0.2714
MHH-NB-11 GDSC1 5.9881 7.6567 3.4464 0.6684
SJNB-14 GDSC1 6.0115 12.6507 1.2146 14.3128
SK-N-FI GDSC1 6.1 7.7189 3.4683 0.5178
KP-N-YN GDSC1 6.1955 8.0277 3.3926 0.7232
CHP-212 GDSC1 6.2001 11.466 1.9025 9.6433
SK-N-BE(2)-M17 GDSC1 6.2094 8.825 3.0853 2.1581
SJNB-10 GDSC1 6.2873 7.9656 3.4517 0.4663
GI-ME-N GDSC1 6.3162 11.6525 1.8887 9.4638
SJNB-5 GDSC1 6.446 8.7492 3.2238 1.2121
SJNB-12 GDSC1 6.5012 8.4775 3.3491 0.6763
NB(TU)1 GDSC1 6.5543 8.238 3.4553 0.3358
GOTO GDSC1 6.7289 8.3706 3.4725 0.2391
SK-N-SH GDSC1 7.0348 15.8793 0.3594 16.2585
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 5.2638 8.6285 2.6352 6.9097
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC202 GDSC1 3.7774 17.3735 -2.8732 35.6496
MDA-MB-231 GDSC1 4.4091 6.291 3.175 5.1656
HCC1419 GDSC1 4.5531 6.9193 2.9717 6.3084
HCC1569 GDSC1 4.6838 8.8078 2.1394 12.1472
MDA-MB-330 GDSC1 4.8307 7.111 3.0704 4.8098
EFM-19 GDSC1 4.871 7.5626 2.8819 6.1068
DU4475 GDSC1 5.0428 11.0736 1.2902 16.6298
BT-20 GDSC1 5.1197 6.8638 3.3584 2.1665
UACC-893 GDSC1 5.1417 17.4133 -1.7805 29.2055
HCC2218 GDSC1 5.1585 7.2138 3.2251 2.9749
MDA-MB-468 GDSC1 5.1648 6.8869 3.3727 1.9982
MDA-MB-436 GDSC1 5.2205 8.1667 2.8247 5.6516
MDA-MB-415 GDSC1 5.228 11.7215 1.1088 17.13
JIMT-1 GDSC1 5.2717 7.9505 2.957 4.593
CAL-148 GDSC1 5.3099 7.3118 3.2663 2.4261
OCUB-M GDSC1 5.3674 7.4362 3.2432 2.4743
HCC1937 GDSC1 5.4295 7.2524 3.354 1.7033
HCC70 GDSC1 5.4761 19.4919 -2.5528 30.3042
UACC-812 GDSC1 5.5832 7.5276 3.3156 1.7091
MDA-MB-175-VII GDSC1 5.6083 7.5852 3.304 1.7403
T-47D GDSC1 5.6385 8.2099 3.0528 3.22
CAMA-1 GDSC1 5.6406 7.9637 3.1607 2.5381
MRK-nu-1 GDSC1 5.6692 7.6089 3.3239 1.5512
CAL-85-1 GDSC1 5.692 11.1192 1.7327 11.9984
MDA-MB-361 GDSC1 5.7125 7.9762 3.1925 2.236
BT-474 GDSC1 5.7951 8.0192 3.2159 1.9831
BT-483 GDSC1 5.8013 7.2909 3.5067 0.5745
CAL-120 GDSC1 5.8147 11.8887 1.4464 13.4607
HCC1500 GDSC1 5.8411 7.6332 3.3931 1.0145
Evsa-T GDSC1 5.868 7.3314 3.5185 0.4891
HCC1187 GDSC1 5.9147 7.7388 3.3842 0.9855
COLO 824 GDSC1 5.9248 10.4934 2.1829 8.4564
HCC1395 GDSC1 5.9693 7.7501 3.4033 0.855
HDQ-P1 GDSC1 5.983 8.0486 3.293 1.3452
HCC1599 GDSC1 6.0293 7.6896 3.4509 0.623
Hs 578T GDSC1 6.2312 8.0751 3.3895 0.7099
MDA-MB-453 GDSC1 6.348 9.1926 3.0012 2.4389
HCC1954 GDSC1 6.3943 7.9912 3.4829 0.3309
HCC2157 GDSC1 6.432 17.7899 -0.9881 23.2964
ZR-75-30 GDSC1 6.4372 14.2116 0.7548 15.7405
HCC1806 GDSC1 6.4376 7.9884 3.4997 0.2747
MDA-MB-157 GDSC1 6.5771 8.3908 3.4098 0.445
BT-549 GDSC1 6.6482 8.202 3.5015 0.2066
HCC38 GDSC1 6.7565 8.423 3.4643 0.2471
MFM-223 GDSC1 6.7927 8.2419 3.5381 0.1186
CAL-51 GDSC1 6.9177 8.4868 3.499 0.1488
HCC1428 GDSC1 7.2304 18.041 -0.5448 19.721
AU565 GDSC1 7.2755 9.3484 3.3315 0.3606
EFM-192A GDSC1 8.005 27.8174 -4.7582 29.4355
MCF-7 GDSC1; CTRP1 8.2171 12.8071 6.1272 12.8125
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MOG-G-CCM GDSC1 3.8464 4.9559 3.3887 5.4079
Hs 683 GDSC1 4.4231 5.9258 3.3629 3.6836
D-392MG GDSC1 4.4956 6.2747 3.2445 4.3843
SF126 GDSC1 4.6728 12.4846 0.3045 23.0821
8-MG-BA GDSC1 4.6985 6.9899 3.0395 5.3848
A-172 GDSC1 4.7152 7.2189 2.9406 6.0863
YH-13 GDSC1 4.7914 6.4998 3.3319 2.9984
LNZTA3WT4 GDSC1 4.9422 6.7836 3.293 2.9466
SW1088 GDSC1 4.9429 7.5103 2.9548 5.3817
LN-18 GDSC1 4.9909 7.6899 2.9011 5.6558
SK-MG-1 GDSC1 5.0614 7.1308 3.2057 3.3037
DBTRG-05MG GDSC1 5.0974 7.658 2.9846 4.7908
AM-38 GDSC1 5.2521 7.3722 3.2077 2.9119
SF295 GDSC1 5.2822 10.3352 1.827 12.5111
D-423MG GDSC1 5.3537 7.8117 3.0691 3.6456
D-542MG GDSC1 5.4886 8.0054 3.0597 3.4482
U-87MG ATCC GDSC1 5.4916 8.3329 2.9142 4.4225
Daoy GDSC1 5.5808 9.1437 2.5958 6.4327
Becker GDSC1 5.6301 22.3321 -3.8455 32.6356
SF539 GDSC1 5.6677 8.8623 2.778 4.9886
D-263MG GDSC1 5.6759 12.9309 0.8425 17.303
U-118MG GDSC1 5.6815 7.6435 3.3156 1.5804
CAS-1 GDSC1 5.7214 7.1965 3.5093 0.6223
PFSK-1 GDSC1 5.7336 7.4647 3.4115 1.0343
Onda 10 GDSC1 5.744 9.6001 2.4855 6.8242
ONS-76 GDSC1 5.8157 7.9797 3.2424 1.8078
GI-1 GDSC1 5.8837 16.0729 -0.5476 23.0931
M059J GDSC1 5.9719 7.8418 3.3692 0.9998
42-MG-BA GDSC1 5.985 8.0324 3.3003 1.3074
LN-405 GDSC1 6.0043 8.0282 3.3107 1.2378
SF268 GDSC1 6.0468 8.1091 3.2979 1.2553
D283 Med GDSC1 6.0908 7.4909 3.5464 0.2939
MOG-G-UVW GDSC1 6.1153 12.4625 1.3753 13.1039
DK-MG GDSC1 6.1268 15.0194 0.1465 19.5177
D-566MG GDSC1 6.1337 8.0078 3.3746 0.8396
YKG-1 GDSC1 6.1452 7.7774 3.4647 0.5033
T98G GDSC1 6.1487 11.0937 2.0438 8.8534
U-251MG GDSC1 6.1744 12.7659 1.27 13.5713
D-502MG GDSC1 6.2554 8.7758 3.1273 1.8767
KS-1 [Human Krukenberg tumour] GDSC1 6.3635 18.1257 -1.203 24.2087
NMC-G1 GDSC1 6.4073 22.6572 -3.4062 30.0068
Onda 11 GDSC1 6.4211 8.9927 3.1171 1.7387
SW1783 GDSC1 6.4617 8.8794 3.1801 1.3942
KNS-42 GDSC1 6.5321 13.8113 1.0102 14.1428
GB-1 GDSC1 6.6955 16.2138 -0.0325 18.8649
KALS-1 GDSC1 6.7241 14.1962 0.9543 13.9836
KINGS-1 GDSC1 6.7354 14.7414 0.7023 15.2778
SNB-75 GDSC1 6.8411 13.3376 1.4331 11.0392
H4 GDSC1 6.8439 13.9945 1.1275 12.7605
KNS-81-FD GDSC1 6.9183 9.2107 3.2455 0.7718
GaMG GDSC1; CTRP1 10.5162 19.985 1.9161 10.8354
LN-229 GDSC1; CTRP1 12.337 20.6225 5.2875 8.9616
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1 5.2994 7.0999 3.3521 1.9085
ETK-1 GDSC1 6.4694 12.6189 1.5337 11.2946
TGBC24TKB GDSC1 6.497 8.3361 3.3989 0.5166
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-319 GDSC1 5.1814 6.9623 3.3489 2.1204
AN3-CA GDSC1 5.4701 10.0801 2.0807 10.2819
EN GDSC1 5.7762 7.6945 3.3396 1.3407
MFE-280 GDSC1 5.9484 8.5985 3.0497 2.7299
HEC-59 CTRP1 7.5659 9.4492 4.8996 1.0919
HEC-151 CTRP1 7.5905 8.3641 7.5451 13.7964
MFE-296 GDSC1 7.6206 31.2941 -6.7596 33.1902
KLE GDSC1; CTRP1 7.6536 13.1779 3.3002 9.1826
JHUEM-2 CTRP1 7.7254 13.4858 5.355 28.7973
ESS-1 GDSC1 7.9035 17.3261 0.2413 14.8899
HEC-108 CTRP1 9.0143 15.3006 3.1546 9.5676
Ishikawa (Heraklio) 02 ER- CTRP1 8.2749 13.9614 3.3253 10.1553
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-54 GDSC1 3.4858 15.5004 -2.1841 35.1766
SW13 GDSC1 4.0769 17.3856 -2.6288 34.2893
A-704 GDSC1 4.2384 18.1905 -2.8976 34.3678
VMRC-RCW GDSC1 4.2791 5.7371 3.3517 4.1867
Caki-1 GDSC1 4.6352 15.9999 -1.4792 29.8101
ACHN GDSC1 5.09 6.6833 3.4209 1.8207
KMRC-20 GDSC1 5.1871 11.2501 1.3104 16.0675
LB1047-RCC GDSC1 5.6097 11.6424 1.423 14.1613
BFTC-909 GDSC1 5.6172 13.2427 0.6474 18.4953
KMRC-1 GDSC1 5.6823 11.3085 1.635 12.6467
BB65-RCC GDSC1 5.7434 12.6036 1.0504 15.9717
A-498 GDSC1 5.8344 19.9174 -2.4864 29.2444
OS-RC-2 GDSC1 6.0819 15.0215 0.1132 19.7887
769-P GDSC1 6.1171 12.0494 1.5735 11.9045
UO-31 GDSC1 6.192 13.6779 0.8436 15.8994
LB996-RCC GDSC1 6.3938 13.9788 0.8371 15.4177
LB2241-RCC GDSC1 6.3974 9.6397 2.8385 3.3006
SW156 GDSC1 6.4623 8.6121 3.2831 0.9492
RXF 393L GDSC1 6.6009 9.3429 3.0597 1.8258
VMRC-RCZ GDSC1 7.1108 16.9125 -0.0838 18.0931
TK-10 GDSC1 7.9239 24.6029 -3.2426 26.4601
SN12C GDSC1 7.9509 19.6697 -0.8371 19.2501
HA7-RCC GDSC1 8.4828 20.8598 -1.0505 18.9341
RCC10RGB GDSC1; CTRP1 8.6962 24.6576 0.6061 30.2222
786-O GDSC1 9.1329 23.5223 -1.8862 20.4544
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2998 GDSC1 3.4416 4.2061 3.3241 7.7757
T84 GDSC1 4.8714 7.2138 3.0483 4.8708
LS411N GDSC1 5.0003 6.672 3.3767 2.2624
COLO205 GDSC1 5.0855 12.0978 0.8163 19.1914
COLO 320HSR GDSC1 5.688 8.1582 3.102 2.824
HCT 15 GDSC1 5.7942 14.9663 -0.0692 21.3802
C2BBe1 GDSC1 5.9414 8.239 3.1966 1.8962
SW626 GDSC1 5.9598 9.7916 2.5286 6.063
SW1417 GDSC1 6.057 8.0077 3.3419 1.0431
SW837 GDSC1 6.087 9.552 2.7098 4.6201
LS1034 GDSC1 6.0897 12.6216 1.2819 13.7191
CaR-1 GDSC1 6.1764 8.0813 3.3646 0.8462
LS513 GDSC1 6.1941 7.8261 3.4661 0.4717
GP5d GDSC1 6.2464 7.9429 3.444 0.5123
SW1463 GDSC1 6.2487 7.8559 3.4763 0.4131
NCI-H716 GDSC1 6.2906 8.0116 3.4363 0.512
CCK-81 GDSC1 6.3164 8.4902 3.2677 1.1355
SNU-C1 GDSC1 6.3647 7.989 3.4727 0.3696
SW48 GDSC1 6.6987 8.5091 3.4135 0.3821
NCI-H747 GDSC1 6.9385 13.2462 1.5358 10.2296
CL-11 GDSC1 7.2152 8.8718 3.4721 0.1315
LS180 GDSC1; CTRP1 7.826 8.4458 7.7834 5.8162
COLO 320 CTRP1 7.8319 9.7815 7.2587 14.7468
SNU-175 CTRP1 8.0291 8.8181 7.8855 8.3234
SNU-C5 CTRP1 8.0315 8.7071 7.9298 7.9481
KM12 GDSC1; CTRP1 8.0432 8.6662 7.9569 4.2769
SNU-81 CTRP1 8.0943 8.6497 8.0179 6.8509
SNU-C4 CTRP1 8.176 8.6387 8.1101 5.6052
SW948 GDSC1; CTRP1 8.176 8.8022 8.0471 3.4193
SNU-61 CTRP1 8.3975 9.2589 8.0517 4.9314
SW620 GDSC1; CTRP1 8.4215 10.1088 7.6502 4.7076
RCM-1 [Human ESC] GDSC1; CTRP1 8.5094 9.3043 8.1274 2.0958
CW-2 GDSC1; CTRP1 8.5659 10.0321 7.8106 3.56
SNU-C2B GDSC1 8.6877 22.1119 -1.5103 20.1063
COLO 678 GDSC1; CTRP1 9.0291 12.6101 6.8915 7.18
HT115 GDSC1; CTRP1 9.0499 11.1078 7.6467 3.398
NCI-H508 CTRP1 9.1537 13.2904 6.6496 14.1062
HCT 8 CTRP1 9.2721 11.731 7.5 6.6415
MDST8 GDSC1; CTRP1 9.3345 12.7987 7.0255 5.9209
HCT 116 GDSC1; CTRP1 9.3477 14.2486 6.3224 9.3357
HT-29 GDSC1; CTRP1 9.5009 13.0468 7.0228 5.631
SNU-1040 CTRP1 9.8315 14.174 6.7074 11.3706
CL-34 CTRP1 9.9892 14.6301 6.596 11.7249
SW480 CTRP1 10.0884 17.9868 5.0313 21.1314
LoVo GDSC1; CTRP1 10.185 15.9398 6.0995 8.8241
CL-40 CTRP1 10.5938 11.87 8.1219 0.2353
HT-55 GDSC1; CTRP1 10.5962 11.8044 8.1453 0.1018
RKO GDSC1; CTRP1 11.0343 12.5743 8.0372 0.1554
LS123 GDSC1; CTRP1 12.051 20.2973 5.2602 9.4836
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 6.0195 7.581 3.487 0.5036
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HLE GDSC1 5.0484 7.0089 3.2534 3.001
SNU-387 GDSC1 5.1325 8.1985 2.753 6.385
HuH-1 GDSC1 5.3466 6.6099 3.5745 0.6595
JHH-1 GDSC1 5.5402 6.8588 3.5614 0.5551
JHH-4 GDSC1 5.5774 7.4131 3.36 1.4718
Huh-7 GDSC1 5.6431 7.7791 3.2404 2.0565
SNU-475 GDSC1 5.9087 8.1324 3.2245 1.7858
Hep-G2/C3A GDSC1 5.9535 7.3468 3.5461 0.356
SNU-423 GDSC1 6.0055 17.0084 -0.9179 24.1405
SK-HEP-1 GDSC1 6.2387 8.584 3.1965 1.5443
JHH-7 GDSC1 6.6881 8.1228 3.5421 0.1319
JHH-6 GDSC1; CTRP1 6.7304 9.2255 4.5634 3.5592
JHH-2 GDSC1 6.7685 9.0262 3.2537 0.8395
Hep 3B2.1-7 GDSC1 7.3876 18.6068 -0.7093 19.9998
SNU-398 GDSC1; CTRP1 7.9109 8.727 7.7927 5.4711
Hep-G2 CTRP1 8.0329 8.5592 7.9798 7.5417
SNU-449 GDSC1; CTRP1 10.3792 19.0251 2.2694 9.5143
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 183 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-14 GDSC1 3.9205 6.0691 2.8985 8.9759
NCI-H2795 GDSC1 4.2817 11.3313 0.5664 23.151
RERF-LC-Sq1 GDSC1 4.2995 6.4949 2.9925 6.9221
NCI-H2373 GDSC1 4.4758 7.4024 2.6772 8.8026
NCI-H290 GDSC1 4.6189 6.6778 3.1352 4.8773
NCI-H2369 GDSC1 4.6821 10.2051 1.446 16.8257
HARA [Human squamous cell lung carcinoma] GDSC1 4.7452 6.6646 3.2257 3.8756
NCI-H522 GDSC1 4.8006 6.5066 3.3344 2.9599
Calu-3 GDSC1 4.8516 8.3043 2.5097 8.9346
LCLC-103H GDSC1 4.8517 6.7003 3.2764 3.2598
SK-MES-1 GDSC1 4.8584 9.4725 1.942 12.991
NCI-H1568 GDSC1 4.8598 6.8587 3.2079 3.7325
NCI-H226 GDSC1 4.8643 6.3412 3.4471 2.0506
NCI-H526 GDSC1 4.8972 9.7436 1.8373 13.5859
NCI-H2170 GDSC1 4.9495 6.4914 3.4283 2.0167
SW1271 GDSC1 4.9804 7.4666 2.9998 4.9589
LB647-SCLC GDSC1 4.9976 7.4077 3.0384 4.6365
UMC-11 GDSC1 4.9991 7.025 3.2168 3.3587
LOU-NH91 GDSC1 5.0014 9.291 2.1356 11.2085
NCI-H1793 GDSC1 5.0189 7.2008 3.148 3.801
NCI-H1355 GDSC1 5.0218 11.8841 0.8737 19.08
NCI-H513 GDSC1 5.0299 6.9425 3.2726 2.9072
NCI-H2444 GDSC1 5.0795 6.2657 3.5905 0.8567
LK-2 GDSC1 5.083 6.9739 3.2892 2.6898
NCI-H345 GDSC1 5.1464 5.9686 3.732 0.2136
A-427 GDSC1 5.1571 7.6033 3.0471 4.2103
NCI-H2196 GDSC1 5.2564 7.3066 3.2392 2.696
BEN GDSC1 5.2659 8.4685 2.7121 6.3518
NCI-H1703 GDSC1 5.2859 7.0161 3.3808 1.7564
HOP-92 GDSC1 5.3015 7.2954 3.2688 2.4241
NCI-H2135 GDSC1 5.3199 7.9828 2.9714 4.3877
IST-SL1 GDSC1 5.3225 9.5087 2.2546 9.4705
NCI-H650 GDSC1 5.3689 7.4983 3.2169 2.6393
NCI-H1869 GDSC1 5.3843 7.6027 3.1796 2.8535
EKVX GDSC1 5.3904 23.7654 -4.7492 34.6846
DMS 273 GDSC1 5.4304 7.614 3.1998 2.6423
NCI-H2595 GDSC1 5.4389 11.3534 1.4425 14.5229
NCI-H810 GDSC1 5.4488 18.0499 -1.857 28.5833
NCI-H1581 GDSC1 5.4568 7.5782 3.2295 2.4107
NCI-H211 GDSC1 5.4576 11.797 1.2395 15.6916
NCI-H510A GDSC1 5.4997 9.5352 2.3603 8.2728
NCI-H2869 GDSC1 5.5036 8.1931 2.9843 3.9224
NCI-H64 GDSC1 5.507 8.8196 2.7003 5.8716
SBC-3 GDSC1 5.5199 17.7643 -1.6602 27.8315
ChaGo-K-1 GDSC1 5.5328 7.4726 3.3136 1.7904
NCI-H1573 GDSC1 5.5353 7.9539 3.1084 3.0446
SBC-5 GDSC1 5.5575 6.6989 3.6271 0.3161
ABC-1 GDSC1 5.5615 7.9092 3.1421 2.7842
NCI-H1650 GDSC1 5.5951 13.0804 0.7108 18.2301
NCI-H1304 GDSC1 5.6151 7.4803 3.3505 1.4752
NCI-H1048 GDSC1 5.6187 7.4684 3.3571 1.4358
NCI-H520 GDSC1 5.6333 7.6184 3.3026 1.7146
NCI-H1930 CTRP1 5.6567 7.6377 4.5818 8.068
NCI-H446 GDSC1 5.6593 8.5318 2.9219 4.0373
HCC78 GDSC1 5.6613 14.3652 0.1284 20.8772
Lu-165 GDSC1 5.6755 7.3263 3.4398 0.9593
CPC-N GDSC1 5.7285 13.744 0.4827 19.0097
NCI-H647 GDSC1 5.7345 9.3605 2.5903 6.1272
HCC33 GDSC1 5.735 7.9878 3.199 2.1648
COR-L95 GDSC1 5.7403 7.3228 3.4693 0.7697
EBC-1 GDSC1 5.7632 7.3777 3.458 0.798
LC-2/ad GDSC1 5.7667 9.3917 2.5955 6.0221
NCI-H720 GDSC1 5.7734 7.083 3.5719 0.3707
NCI-H82 GDSC1 5.7845 7.6469 3.3624 1.2177
NCI-H2803 GDSC1 5.8085 7.5799 3.3995 1.0163
COR-L88 GDSC1 5.8125 14.3181 0.2625 19.8344
NCI-H2085 GDSC1 5.8321 10.8698 1.9458 10.2527
NCI-H1944 GDSC1 5.8371 9.202 2.7236 5.0107
NCI-H2029 GDSC1 5.839 7.1002 3.5906 0.2856
EPLC-272H GDSC1 5.864 9.157 2.7593 4.72
Lu-134-A GDSC1 5.8656 8.2239 3.1656 2.1716
Lu-65 GDSC1 5.8756 8.0135 3.2572 1.6516
NCI-H1436 GDSC1 5.8834 7.5568 3.4406 0.7709
NCI-H748 GDSC1 5.9059 11.6482 1.6239 12.1277
IA-LM GDSC1 5.9372 7.1999 3.5919 0.2426
NCI-H1693 GDSC1 5.9457 11.2476 1.8412 10.6485
NCI-H1975 GDSC1 5.9691 14.1937 0.4364 18.572
NCI-H2591 GDSC1 5.984 8.0277 3.3018 1.3015
DMS 53 GDSC1 5.9891 7.9958 3.3166 1.2248
NCI-H1648 GDSC1 6.0006 11.0639 1.9637 9.7218
NCI-H2009 GDSC1 6.0341 8.5836 3.0993 2.3149
DMS 79 GDSC1 6.0559 7.8382 3.4062 0.7738
NCI-H196 GDSC1 6.0662 7.3985 3.5698 0.2469
Calu-6 GDSC1 6.0729 8.2152 3.2677 1.3732
Lu-99A GDSC1 6.0891 9.2983 2.8226 3.8975
NCI-H69 GDSC1 6.0966 8.5613 3.1391 2.0101
NCI-H838 GDSC1 6.1035 11.593 1.7808 10.6464
NCI-H1734 GDSC1 6.1076 7.9225 3.3959 0.775
DMS 114 GDSC1 6.1394 7.8854 3.4228 0.6508
NCI-H2171 GDSC1 6.1463 7.8248 3.4478 0.5585
NCI-H2405 GDSC1 6.1537 9.8735 2.6045 5.1753
NCI-H727 GDSC1 6.1628 31.3828 -7.9333 37.0126
SBC-1 GDSC1 6.1749 7.6245 3.5306 0.2997
NCI-H847 GDSC1 6.1853 7.4458 3.596 0.1572
SHP-77 GDSC1 6.1876 7.4862 3.5831 0.1802
NCI-H187 GDSC1 6.2057 7.3851 3.6236 0.1093
PaCa-3 GDSC1 6.233 10.7797 2.2409 7.3845
NCI-H1770 GDSC1 6.2398 7.9645 3.4336 0.5499
NCI-H1792 GDSC1 6.2411 11.2922 2.0093 8.8656
NCI-H1651 GDSC1 6.2417 9.5334 2.8026 3.7642
NCI-H23 GDSC1 6.2465 8.1684 3.3608 0.8075
NCI-H1688 GDSC1 6.2488 7.9423 3.4452 0.5071
NCI-H1092 GDSC1 6.2494 7.841 3.4819 0.3969
NCI-H1563 GDSC1 6.2504 7.9675 3.4367 0.5337
NCI-H2227 GDSC1 6.2687 8.0374 3.4183 0.5836
NCI-H2087 GDSC1 6.3219 13.9431 0.8052 15.7684
NCI-H3122 GDSC1 6.3322 13.2779 1.1312 13.9665
NCI-H2804 GDSC1 6.3447 10.0149 2.6486 4.5445
NCI-H358 GDSC1 6.3567 7.9924 3.4684 0.3845
RERF-LC-MS GDSC1 6.3641 7.8686 3.5146 0.2669
Lu-139 GDSC1 6.3811 8.1336 3.4273 0.4913
NCI-H292 GDSC1 6.4165 11.0496 2.2274 7.0877
NCI-H661 GDSC1 6.4171 8.16 3.4316 0.4599
LCLC-97TM1 GDSC1 6.42 13.942 0.8725 15.1634
Ms-1 GDSC1 6.431 8.1813 3.4293 0.4598
Lu-135 GDSC1 6.4338 8.1483 3.4421 0.4218
IST-SL2 GDSC1 6.4576 12.2212 1.7125 10.2378
NCI-H2291 GDSC1 6.4726 8.2992 3.4028 0.5177
NCI-H1838 GDSC1 6.481 8.2254 3.4324 0.4267
NCI-H1437 GDSC1 6.5052 12.4135 1.6527 10.4935
NCI-H1666 GDSC1 6.5122 8.5841 3.3141 0.7936
NCI-H2818 GDSC1 6.5514 8.5161 3.3548 0.6265
HOP-62 GDSC1 6.6106 13.6635 1.1323 13.2801
NCI-H209 GDSC1 6.634 8.8885 3.2501 0.9482
NCI-H524 GDSC1 6.7559 8.6025 3.4018 0.3883
NCI-H1623 GDSC1 6.7613 8.4102 3.4704 0.2337
NCI-H1993 GDSC1 6.7714 14.5344 0.8248 14.558
NCI-H322M GDSC1 6.7856 10.94 2.4843 4.7985
NCI-H2347 GDSC1 6.8698 9.2143 3.2248 0.8758
NCI-H1155 GDSC1 6.9154 8.1544 3.6076 0.0399
NCI-H1435 GDSC1; CTRP1 6.939 13.5224 2.6407 14.4624
A-549 GDSC1 6.9402 13.8455 1.2586 11.8128
NCI-H2461 GDSC1 7.0332 17.7277 -0.5299 20.1213
SW1573 GDSC1 7.1366 19.669 -1.3993 23.0156
NCI-H1105 CTRP1 7.2226 15.2879 4.0096 36.4444
HCC2108 CTRP1 7.2717 12.2726 5.5303 30.2653
NCI-H2228 GDSC1 7.273 16.6947 0.1295 16.7743
NCI-H1876 GDSC1; CTRP1 7.324 9.8048 6.7345 12.3005
NCI-H1915 GDSC1; CTRP1 7.3845 9.3671 4.8512 1.1438
HCC44 GDSC1 7.4038 19.6755 -1.2142 21.7899
COLO 668 GDSC1; CTRP1 7.4261 10.6611 4.3217 3.7627
RERF-LC-KJ GDSC1; CTRP1 7.4497 9.5287 4.8165 1.2296
NCI-H2286 CTRP1 7.4539 8.9103 5.0554 0.5079
NCI-H2731 GDSC1 7.4956 16.1548 0.5303 14.3965
NCI-H2342 GDSC1; CTRP1 7.7779 8.9719 7.5581 6.9887
COR-L105 GDSC1 7.88 24.3346 -3.1431 26.3116
LC-1/sq GDSC1 7.9088 10.1156 3.2936 0.2535
NCI-H2081 GDSC1; CTRP1 7.9289 11.6365 6.4528 11.9449
NCI-H1836 GDSC1; CTRP1 7.9606 14.8696 4.8758 19.2244
NCI-H2073 CTRP1 8.0002 8.7362 7.8856 8.4969
NCI-H3255 GDSC1; CTRP1 8.0589 8.7465 7.9448 4.2779
Sq-1 CTRP1 8.0763 8.6374 8.0026 7.0861
NCI-H841 GDSC1; CTRP1 8.0841 8.647 8.0078 3.9074
NCI-H1781 GDSC1; CTRP1 8.1262 8.8915 7.9577 3.9974
HCC1195 CTRP1 8.1277 9.4457 7.7065 9.3136
COR-L51 CTRP1 8.1364 13.1753 5.8735 23.8724
HCC1833 CTRP1 8.1431 14.2084 5.3641 26.774
HCC827 GDSC1; CTRP1 8.1626 15.073 4.9493 18.395
NCI-H2122 GDSC1; CTRP1 8.2473 14.1142 5.5008 15.7211
HCC2935 CTRP1 8.2673 9.223 7.9474 6.489
NCI-H2030 GDSC1; CTRP1 8.2709 16.8252 4.1664 21.2935
NCI-H1694 GDSC1; CTRP1 8.281 9.0358 8.0497 3.0848
NCI-H2722 GDSC1 8.2937 18.1353 0.1097 14.6845
HCC4006 CTRP1 8.3402 10.8773 7.1964 12.8222
SCLC-21H CTRP1 8.3442 9.1919 8.0354 5.3302
HCC1359 CTRP1 8.394 8.9747 8.1878 3.7367
NCI-H2141 GDSC1; CTRP1 8.4269 9.4583 7.9791 3.0426
NCI-H596 GDSC1; CTRP1 8.5073 12.2026 6.6767 9.3955
CAL-12T GDSC1; CTRP1 8.6568 9.8761 7.9615 2.602
COLO 699 CTRP1 8.6599 10.4919 7.6571 7.3803
NCI-H1963 GDSC1; CTRP1 8.7515 13.8742 6.0421 11.9643
NCI-H1755 GDSC1; CTRP1 8.9191 11.4301 7.3922 4.9088
NCI-H2110 GDSC1; CTRP1 8.9972 13.6348 6.3578 9.8869
NCI-H441 GDSC1; CTRP1 9.1793 14.1644 6.236 10.0976
NCI-H2172 GDSC1; CTRP1 9.2128 17.994 4.3563 18.3574
NCI-H1299 GDSC1 9.4024 22.5739 -1.2633 17.9262
NCI-H460 GDSC1; CTRP1 9.4462 11.8472 7.561 3.1397
COR-L23 GDSC1; CTRP1 9.5501 10.7849 8.0991 0.6797
T3M-10 CTRP1 9.9743 19.5198 4.1895 25.263
HCC15 GDSC1; CTRP1 10.4564 16.2338 6.1434 8.1558
SK-LU-1 GDSC1; CTRP1 10.7012 22.237 3.3932 18.8003
LXF 289 GDSC1; CTRP1 11.1333 21.208 1.7241 10.6859
NCI-H2023 GDSC1; CTRP1 11.8816 23.216 3.76 15.4492
⏷ Show the Full List of 183 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 6.0812 8.5873 3.121 2.1294
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-180 GDSC1 0.6936 8.2989 -1.2816 45.493
KYSE-270 GDSC1 5.0627 8.1549 2.7275 6.7488
OE21 GDSC1 5.1817 10.1004 1.8697 12.5148
KYSE-140 GDSC1 5.3412 7.4759 3.2115 2.7231
TE-11 GDSC1 5.3452 9.3702 2.3363 8.8355
TE-9 GDSC1 5.4027 7.3402 3.3032 2.0441
KYSE-450 GDSC1 5.4198 7.1369 3.3973 1.471
KYSE-70 GDSC1 5.8447 7.6981 3.3693 1.1217
T.T GDSC1 6.0241 12.4267 1.3308 13.6011
TE-6 GDSC1 6.0512 8.02 3.3346 1.0813
EC-GI-10 GDSC1 6.0632 8.1093 3.3051 1.2048
COLO 680N GDSC1 6.068 8.2292 3.2599 1.4167
TE-10 GDSC1 6.2379 8.1321 3.3709 0.7749
KYSE-510 GDSC1 6.3269 7.8667 3.5017 0.311
OE33 GDSC1 6.3312 8.0056 3.4541 0.4368
OE19 GDSC1 6.3981 11.5293 1.9966 8.5973
TE-15 GDSC1 6.4042 8.8286 3.1745 1.4776
TE-1 GDSC1 6.4425 14.3043 0.7139 15.939
KYSE-520 GDSC1 6.4755 13.5004 1.1207 13.6714
TE-8 GDSC1 6.4971 10.8908 2.3459 6.1731
KYSE-150 GDSC1 6.9781 13.2123 1.5757 9.9127
KYSE-410 GDSC1 7.2732 17.5212 -0.2656 18.4906
TE-5 GDSC1 8.703 25.0629 -2.9163 24.156
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OC 314 GDSC1 4.8124 6.3619 3.4077 2.4208
Kuramochi GDSC1 4.8377 6.8843 3.1819 3.9736
EFO-21 GDSC1 5.2277 7.1642 3.2859 2.4432
FU-OV-1 GDSC1 5.3864 11.4752 1.3454 15.2658
Caov-4 GDSC1 5.4258 8.3706 2.8577 4.9524
OVTOKO GDSC1 5.5985 14.9957 -0.2292 22.6074
TOV-21G GDSC1 5.7822 7.5856 3.3856 1.1077
OAW28 GDSC1 5.936 9.8268 2.4983 6.3166
OVCAR-3 GDSC1 6.0942 10.4662 2.3007 7.292
TOV-112D GDSC1 6.1021 8.0159 3.3581 0.9332
OVCAR-5 GDSC1 6.2096 12.2477 1.5403 11.8782
ES-2 GDSC1 6.2187 8.6677 3.1538 1.7828
OVMANA CTRP1 6.9208 8.8418 4.8417 2.3223
OVCAR-4 GDSC1; CTRP1 7.4703 10.7384 6.455 13.2013
JHOS-4 CTRP1 7.4808 14.9758 2.3198 18.4092
SK-OV-3 GDSC1 7.6202 25.2521 -3.7807 28.2583
OVCAR-8 GDSC1; CTRP1 7.6636 8.9615 7.4404 7.9094
COV318 CTRP1 7.6945 13.0243 3.3989 11.1265
RMUG-S CTRP1 7.6951 12.9178 5.6083 27.5947
COV434 CTRP1 7.8702 8.9988 7.6449 11.25
OVKATE GDSC1; CTRP1 7.8933 8.4909 7.8458 5.3006
RMG-I GDSC1; CTRP1 7.9493 9.7644 7.3822 7.2994
JHOC-5 CTRP1 7.9561 12.0079 6.294 21.9032
JHOM-1 CTRP1 7.9959 13.0686 5.8033 24.9701
OVISE GDSC1 8.0381 17.2232 0.3742 13.9986
IGROV-1 GDSC1; CTRP1 8.0719 9.0426 7.8363 4.7419
A2780 GDSC1; CTRP1 8.1208 8.8551 7.9673 3.9695
OV-90 GDSC1; CTRP1 8.5863 16.9303 4.3786 19.7078
OAW42 GDSC1; CTRP1 8.8827 10.0113 8.0609 1.6782
EFO-27 GDSC1; CTRP1 8.9855 11.3999 7.4569 4.4558
OV7 CTRP1 9.3488 13.0494 6.9132 11.3172
COV362 CTRP1 9.4777 12.9589 7.0492 9.7816
COV644 CTRP1 9.5442 11.5078 7.7797 3.5672
OVK18 CTRP1 9.8491 19.9886 3.8615 26.8965
Caov-3 GDSC1; CTRP1 9.9424 11.8167 7.8635 1.1931
TYK-nu GDSC1; CTRP1 10.0137 14.8729 6.4959 7.2631
SNU-840 CTRP1 10.8514 17.7718 5.6735 15.3317
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BxPC-3 GDSC1 4.2442 7.5256 2.4363 11.401
Hs 766T GDSC1 4.3819 5.9093 3.3419 3.9599
Panc 02.03 GDSC1 4.4942 6.0159 3.3683 3.451
Capan-1 GDSC1 4.7529 7.4637 2.8484 6.6783
HPAF-II GDSC1 4.7767 16.2969 -1.5137 29.4898
Panc 03.27 GDSC1 4.8406 7.1038 3.0803 4.7118
KP-4 GDSC1 5.1275 7.4471 3.1008 3.8965
DAN-G GDSC1 5.2038 7.2321 3.2427 2.7702
SU.86.86 GDSC1 5.3269 7.0718 3.3782 1.7104
KP-2 GDSC1 5.3759 6.9217 3.4642 1.1637
SW1990 GDSC1 5.4328 10.31 1.9445 11.305
PaTu 8988t GDSC1 5.6021 10.3539 2.0386 10.2217
HuP-T4 GDSC1 5.6757 11.1493 1.7071 12.206
Panc 10.05 GDSC1 5.7006 9.7701 2.3791 7.6547
MIA PaCa-2 GDSC1 5.7192 15.5583 -0.4164 23.0297
KP-3 GDSC1 5.7863 8.1083 3.1743 2.2349
PSN1 GDSC1 5.8403 13.9747 0.4507 18.855
KP-1N GDSC1 5.9639 8.3436 3.1644 2.044
HPAC GDSC1 6.0621 7.3871 3.5722 0.2428
AsPC-1 GDSC1 6.0678 8.7946 3.0278 2.6802
HuP-T3 GDSC1 6.0993 14.6123 0.3253 18.7571
PL4 GDSC1 6.3096 8.1704 3.3857 0.6706
Capan-2 GDSC1 6.4233 13.4348 1.1173 13.8184
MZ-PC-1 GDSC1 6.4291 15.4486 0.152 18.7062
Panc 04.03 GDSC1 6.5835 8.135 3.5016 0.2245
Panc 08.13 GDSC1 6.7903 21.1156 -2.3583 26.6504
CFPAC-1 GDSC1 7.152 13.3143 1.6337 9.2145
SUIT-2 GDSC1 7.2029 16.2264 0.3058 16.1225
YAPC GDSC1 8.2714 18.1868 0.0717 14.897
PaTu 8902 GDSC1; CTRP1 8.9914 14.9825 3.284 6.8467
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1 5.9623 7.5728 3.4672 0.6092
NCI-H28 GDSC1 6.0298 7.6153 3.4785 0.5259
NCI-H2052 GDSC1 6.283 8.7124 3.1656 1.6492
NCI-H2452 GDSC1 6.5639 8.9312 3.2044 1.1918
MSTO-211H GDSC1 6.7348 8.7739 3.3327 0.5936
IST-Mes1 GDSC1 7.7073 19.3018 -0.8253 19.7288
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1 5.5709 9.7002 2.3287 8.3158
VCaP GDSC1 5.6908 7.6424 3.3205 1.5421
DU145 GDSC1 6.5482 13.3346 1.2472 12.7814
PC-3 GDSC1 6.5549 8.8544 3.23 1.0914
22Rv1 GDSC1 6.8011 13.7937 1.1944 12.4872
PaCa-3 CTRP1 10.7624 23.1665 0.5999 18.1548
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 5.1015 13.7712 -0.0007 23.099
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 940.T GDSC1 3.968 151.9978 -70.0255 48.5284
COLO 792 GDSC1 4.0374 5.1746 3.4436 4.2547
COLO 800 GDSC1 4.1006 5.121 3.521 3.4287
RPMI-7951 GDSC1 4.1723 5.6302 3.3237 4.7416
DJM-1 GDSC1 4.429 6.2611 3.204 4.8842
SK-MEL-2 GDSC1 4.5289 16.7485 -1.939 31.3772
GAK GDSC1 4.7063 27.6429 -7.2382 39.0433
IGR-37 GDSC1 4.7843 6.0751 3.5202 1.7152
SK-MEL-24 GDSC1 4.8069 8.8864 2.1923 11.3858
MZ-MEL-2 GDSC1 4.8266 8.1484 2.5678 8.5753
LOX-IMVI GDSC1 4.8734 6.6584 3.3089 2.9813
VMRC-MELG GDSC1 4.9103 8.0669 2.6661 7.6084
A-431 GDSC1 5.0731 9.2115 2.2254 10.3647
MMAc-SF GDSC1 5.1204 8.194 2.7472 6.4577
A2058 GDSC1 5.1413 8.8709 2.4376 8.6542
LB2518-MEL GDSC1 5.2388 7.2018 3.2755 2.4909
WT2-iPS GDSC1 5.2586 10.7699 1.598 14.0707
A101D GDSC1 5.261 6.8545 3.4362 1.4676
COLO 679 GDSC1 5.2757 13.3626 0.3347 21.0439
WM115 GDSC1 5.2769 9.6681 2.1466 10.349
COLO 829 GDSC1 5.3148 7.716 3.0896 3.584
SK-MEL-30 GDSC1 5.5519 6.8705 3.5618 0.5449
MZ-MEL-7 GDSC1 5.5578 7.8395 3.1704 2.613
WM278 GDSC1 5.568 10.3858 2.0004 10.567
A-388 GDSC1 5.6604 11.0542 1.7424 12.0204
COLO 783 GDSC1 5.6941 7.1278 3.5238 0.5865
SK-MEL-3 GDSC1 5.7243 7.0537 3.5634 0.4253
LB373-MEL-D GDSC1 5.7488 7.2648 3.4949 0.6581
CHL-1 GDSC1 5.7656 7.6104 3.3683 1.2089
UACC-257 GDSC1 5.7908 7.0871 3.5771 0.346
G-361 GDSC1 5.8592 8.5392 3.0284 2.9996
IGR-1 GDSC1 5.921 7.5006 3.4773 0.6006
Hs 938.T GDSC1 6.018 7.4897 3.5195 0.4017
CP66-MEL GDSC1 6.0776 12.4431 1.3592 13.2956
MeWo GDSC1 6.0819 7.5273 3.5303 0.3401
451Lu GDSC1 6.1274 8.103 3.3355 1.008
RVH-421 GDSC1 6.1701 13.5543 0.8881 15.7182
M14 GDSC1 6.1725 8.1271 3.3455 0.9272
HMV-II GDSC1 6.1762 9.0195 2.9879 2.7538
G-mel GDSC1 6.1991 19.9588 -2.2291 27.6918
SH-4 GDSC1 6.225 13.3084 1.0442 14.7238
WM35 GDSC1 6.3765 15.4281 0.1249 18.9639
HT-144 GDSC1 6.4707 8.3723 3.3756 0.6053
Mel JuSo GDSC1 6.4733 8.3447 3.3866 0.5681
WM1552C GDSC1 6.484 8.7952 3.2225 1.1839
WM793 GDSC1 6.4866 18.8462 -1.4665 24.7674
CP50-MEL-B GDSC1 6.4932 8.1474 3.4645 0.337
Mel Ho GDSC1 6.5989 13.712 1.1016 13.4784
UACC-62 GDSC1 6.8851 21.2858 -2.3722 26.4732
IST-MEL1 GDSC1 7.2898 18.8485 -0.8935 20.9097
Hs 852.T CTRP1 8.067 16.3914 2.0428 18.1837
IPC-298 GDSC1 9.0439 20.0359 -0.3059 15.0031
SK-MEL-1 GDSC1; CTRP1 9.3487 11.9835 7.431 3.9204
SK-MEL-5 GDSC1; CTRP1 9.5173 16.681 5.2473 13.9909
SK-MEL-28 GDSC1; CTRP1 9.76 17.8322 4.862 15.1452
A-375 GDSC1; CTRP1 9.87 14.2098 6.7167 6.4609
EquiPSC Line K2 GDSC1 6.2517 11.8893 1.7369 10.5665
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 5.5593 10.1671 2.0992 9.9222
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
STS-0421 GDSC1 3.5356 4.6339 3.2446 7.8849
G-401 GDSC1 3.8612 5.1237 3.3187 5.8976
GCT GDSC1 3.9699 14.4058 -1.228 31.1757
SW872 GDSC1 5.1072 8.6236 2.5331 8.053
Hs 633.T GDSC1 5.272 8.7628 2.577 7.3075
SW982 GDSC1 5.5311 7.2907 3.3878 1.38
MES-SA GDSC1 5.814 7.0828 3.5874 0.3053
EW-8 GDSC1 5.8195 7.8117 3.3125 1.4293
Rh41 GDSC1 5.9185 7.991 3.2865 1.449
TE 441.T GDSC1 5.9241 7.1372 3.6089 0.2084
KYM-1 GDSC1 5.9826 7.4282 3.528 0.3944
SK-UT-1 GDSC1 6.2346 8.171 3.3549 0.8396
Rh30 GDSC1 6.2794 14.59 0.4633 17.617
VA-ES-BJ GDSC1 6.3597 15.7973 -0.0665 19.8583
MFH-ino GDSC1 6.5862 15.3244 0.3213 17.5218
A-204 GDSC1 6.7372 15.0412 0.5603 15.9901
G-402 GDSC1 6.9579 14.6658 0.8847 13.8068
SK-LMS-1 GDSC1 7.3661 16.9969 0.0474 16.9313
SW684 GDSC1 7.8181 23.0063 -2.5397 24.9138
RKN GDSC1; CTRP1 8.8372 11.1838 7.4517 4.7785
HT-1080 GDSC1; CTRP1 9.0822 13.593 6.4448 9.2804
RD GDSC1 9.395 23.2988 -1.6089 19.0941
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Fu97 GDSC1 3.93 4.9339 3.4734 4.4136
MKN45 GDSC1 5.3394 6.3024 3.686 0.252
SCH GDSC1 5.4091 7.4727 3.2497 2.3633
RF-48 GDSC1 5.4582 12.0218 1.1299 16.3276
MKN28 GDSC1 5.6222 8.1115 3.0869 3.0303
IM95 GDSC1 5.7577 8.3048 3.0758 2.8725
SNU-5 GDSC1 5.7726 7.4269 3.4432 0.8537
RERF-GC-1B GDSC1 5.7907 8.4057 3.0497 2.9798
TGBC11TKB GDSC1 5.8657 7.95 3.2784 1.5522
SNU-16 GDSC1 5.9339 7.1313 3.6145 0.1932
TMK-1 GDSC1 5.9605 12.1207 1.4345 13.1485
23132/87 GDSC1 6.0091 13.922 0.5973 17.6639
NCI-N87 GDSC1 6.0947 8.4104 3.1997 1.6907
ECC10 GDSC1 6.1095 8.2 3.2901 1.2293
OCUM-1 GDSC1 6.3015 8.1676 3.3835 0.684
SNU-1 GDSC1 6.3035 8.8968 3.1009 1.9572
MKN1 GDSC1 6.389 7.9067 3.5104 0.2676
NUGC-3 GDSC1 6.4554 8.3027 3.3949 0.5517
NUGC-4 GDSC1 6.5423 8.5979 3.3211 0.7477
HGC-27 GDSC1 6.6716 8.9968 3.2249 1.0186
HSC-39 GDSC1 6.6951 8.0943 3.554 0.1148
MKN7 GDSC1 6.7771 8.324 3.5052 0.1687
GCIY GDSC1 7.2528 17.0127 -0.0359 17.5559
MKN74 CTRP1 7.3828 10.3434 4.4382 4.3196
AGS GDSC1; CTRP1 7.7246 8.789 7.5696 7.1162
SNG-M GDSC1; CTRP1 7.436 10.2294 4.5167 2.6919
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ML-1 [Human leukemia] GDSC1 3.955 16.4556 -2.2653 33.8756
IHH-4 GDSC1 4.5761 6.1592 3.3545 3.3435
ASH-3 GDSC1 4.8125 12.6064 0.3538 22.3949
KMH-2 GDSC1 5.1497 7.4978 3.091 3.9176
TT GDSC1 5.342 6.8611 3.4728 1.1595
8505C GDSC1 5.3703 7.8478 3.0625 3.6578
HTC-C3 GDSC1 5.4423 9.0334 2.5598 7.0107
BHT-101 GDSC1 5.5047 10.4254 1.9383 11.1516
8305C GDSC1 5.5235 8.3428 2.9285 4.2601
CAL-62 GDSC1 5.6818 12.134 1.2351 15.0833
K5 GDSC1 5.7251 8.8412 2.8211 4.5816
B-CPAP GDSC1 5.862 11.2998 1.7609 11.3748
CGTH-W-1 GDSC1 5.9514 10.6998 2.1033 8.9233
FTC-133 GDSC1 6.003 7.5359 3.4969 0.4805
WRO GDSC1 6.6199 7.9322 3.5823 0.0923
TT2609-C02 GDSC1 6.7464 12.5119 1.7567 9.3292
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BICR 22 GDSC1 4.5846 6.217 3.3327 3.484
BICR 31 GDSC1 4.9115 7.1876 3.0867 4.4907
BICR 10 GDSC1 4.9139 8.2293 2.59 8.1628
PCI-38 GDSC1 4.9479 14.2124 -0.3394 24.9784
FaDu GDSC1 5.0276 10.7984 1.4145 15.9191
OSC-20 GDSC1 5.1469 7.4145 3.1274 3.6687
KON GDSC1 5.1895 8.1891 2.7944 5.9445
UPCI-SCC-090 GDSC1 5.2338 7.578 3.1046 3.6459
BB49-HNC GDSC1 5.2509 8.6913 2.5971 7.2165
HO-1-N-1 GDSC1 5.3028 10.4222 1.7992 12.6365
PCI-15A GDSC1 5.4178 7.0006 3.452 1.1775
HSC-2 GDSC1 5.4241 9.4441 2.3537 8.5096
JHU-029 GDSC1 5.459 10.2349 1.9987 10.8688
Detroit 562 GDSC1 5.6534 7.8361 3.2216 2.1519
PCI-06A GDSC1 5.6688 8.2243 3.063 3.102
Ca9-22 GDSC1 5.6708 10.0176 2.2437 8.6547
HSC-4 GDSC1 5.7839 7.1885 3.5376 0.476
HSC-3 GDSC1 5.8237 7.3974 3.4761 0.6754
HO-1-u-1 GDSC1 5.9628 7.5551 3.474 0.5842
SCC-25 GDSC1 6.0737 7.9524 3.3703 0.9059
PE/CA-PJ15 GDSC1 6.1117 7.9171 3.3996 0.7575
BHY GDSC1 6.1706 12.2674 1.5052 12.1868
CAL-27 GDSC1 6.1878 9.9322 2.5978 5.1541
PCI-30 GDSC1 6.2014 8.0787 3.3759 0.7827
SKN-3 GDSC1 6.2724 8.9296 3.0727 2.1457
KOSC-2 GDSC1 6.3162 15.6778 -0.0392 19.8515
LB771-HNC GDSC1 6.4172 12.2381 1.679 10.5365
OSC-19 GDSC1 6.4709 8.1898 3.4413 0.4069
SAT [Human HNSCC] GDSC1 6.4777 10.0664 2.6979 4.0158
CAL-33 GDSC1 6.6383 12.5428 1.6759 10.0532
SCC-4 GDSC1 6.6448 16.4427 -0.1788 19.6217
JHU-011 GDSC1 6.683 8.8421 3.2874 0.7755
DOK GDSC1 6.7779 9.0609 3.2445 0.8663
PCI-04B GDSC1 6.8741 8.8569 3.356 0.4573
SAS GDSC1 6.8791 8.8798 3.3498 0.4719
BB30-HNC GDSC1 6.9041 13.7164 1.2961 11.6819
NCI-H3118 GDSC1 6.9575 8.816 3.401 0.3156
BICR 78 GDSC1 7.0563 8.6343 3.4971 0.1264
JHU-022 GDSC1 7.3314 16.1458 0.4285 15.2505
SCC-15 GDSC1 7.4923 20.2526 -1.432 22.3257
SCC-9 GDSC1; CTRP1 9.2719 10.9073 7.8904 1.8718
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KU-19-19 GDSC1 4.0446 8.4251 1.8246 16.5591
BFTC-905 GDSC1 4.8772 6.4114 3.4231 2.1866
CAL-29 GDSC1 4.9113 8.8783 2.2723 10.4976
HT-1376 GDSC1 4.9114 8.0751 2.6629 7.6291
RT-4 GDSC1 5.4252 7.3932 3.2923 2.0755
TCCSUP GDSC1 5.5838 7.4546 3.346 1.5394
SW1710 GDSC1 6.0537 17.5319 -1.14 24.7842
RT-112 GDSC1 6.3352 12.094 1.6943 10.6335
647V GDSC1 6.4677 7.8638 3.5531 0.1617
5637 GDSC1 6.5665 11.4292 2.1436 7.3134
SW780 GDSC1 6.6334 8.2004 3.4968 0.2193
T24 GDSC1 7.4413 14.7564 1.1474 11.3463
639V GDSC1 7.482 24.1899 -3.3605 27.6194
J82 GDSC1 7.9454 17.4705 0.2003 14.9887
UM-UC-3 GDSC1 8.6475 18.762 0.0389 14.3028
HT-1197 GDSC1 9.4976 26.507 -3.0671 23.0931
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
C-4-I GDSC1 4.4719 13.3932 -0.3094 26.3778
SW962 GDSC1 4.8283 7.224 3.0151 5.2263
DSH1 GDSC1 4.8685 9.3415 2.0139 12.4609
HeLa GDSC1 4.9856 9.7064 1.9207 12.7489
DoTc2 4510 GDSC1 5.1341 11.5857 1.1058 17.4328
NEC8 GDSC1 5.4429 7.504 3.2541 2.2811
SKG-IIIa GDSC1 5.5681 7.6621 3.2516 2.1012
SW756 GDSC1 5.5907 8.6417 2.8326 4.7757
C-33 A GDSC1 5.643 11.8945 1.324 14.6653
OVMIU GDSC1 5.7012 10.613 1.9812 10.3502
NCC-IT GDSC1 5.702 10.8236 1.8812 11.0086
PA-1 GDSC1 5.7744 7.603 3.3752 1.1657
NT2-D1 GDSC1 5.9079 7.8407 3.3414 1.19
Ca Ski GDSC1 6.0018 12.7908 1.1403 14.7641
HT-3 GDSC1 6.0247 8.0088 3.3274 1.1393
JEG-3 GDSC1 6.0261 7.4402 3.5402 0.3381
HEC-1 GDSC1 6.0585 8.945 2.959 3.1047
SW954 GDSC1 6.101 7.8415 3.4235 0.6745
LB831-BLC GDSC1 6.1021 7.8842 3.408 0.732
SiHa GDSC1 6.1028 14.5303 0.3678 18.545
MS751 GDSC1 6.1507 8.0608 3.3616 0.8788
JAR GDSC1 6.2733 7.8315 3.4942 0.3523
OMC-1 [Human cervical carcinoma] GDSC1 6.3562 9.3454 2.9417 2.7623
BPH-1 GDSC1 6.8257 9.7407 3.0038 1.8576
SKN GDSC1 6.8699 8.6751 3.4181 0.3075
ME-180 GDSC1 6.9341 8.9284 3.3531 0.439
SiSo GDSC1 6.9859 14.6276 0.9209 13.5515
CAL-39 GDSC1 6.9944 8.9859 3.3552 0.4088
KGN GDSC1 7.8595 21.5361 -1.7972 22.6985
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug

References

1 A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20523-8.