Details of the Drug

General Information of Drug (ID: DMU4CS8)

Drug Name

MEDI6012

Synonyms

RhLCAT; ACP-501

Indication

Disease Entry	ICD 11	Status	REF
Coronary artery disease	BA80	Phase 2	[1]
Acute coronary syndrome	BA41	Phase 1	[2]
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Cross-matching ID

Repurposed Drugs (RPD)

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Lecithin-cholesterol acyltransferase (LCAT)	TTGZ91P	LCAT_HUMAN	Modulator	[3]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	ClinicalTrials.gov (NCT01554800) Effect of ACP-501 on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Subjects With Coronary Artery Disease. U.S. National Institutes of Health.
3	Familial lecithin-cholesterol acyltransferase (LCAT) deficiency; a differential of proteinuria. J Nephropathol. 2015 January; 4(1): 25-28.