Details of the Drug

General Information of Drug (ID: DMU59UK)

Drug Name

BIRT 2584

Synonyms

QSNSVPRLHYSSQG-AMXDTQDGSA-N; UNII-24P4O1J71F; 24P4O1J71F; SCHEMBL4017930; BIRT-2584; (S)-2-[(R)-7-(3,5-Dichloro-phenyl)-5-methyl-6-oxo-5-(4-trifluoromethoxy-benzyl)-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide; 688756-00-5

Indication

Disease Entry	ICD 11	Status	REF
Psoriasis vulgaris	EA90	Discontinued in Phase 2	[1]

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C23H20Cl2F3N5O5S
Canonical SMILES: CC(C(=O)N)NS(=O)(=O)C1=CN=C2N1C(C(=O)N2C3=CC(=CC(=C3)Cl)Cl)(C)CC4=CC=C(C=C4)OC(F)(F)F
InChI: InChI=1S/C23H20Cl2F3N5O5S/c1-12(19(29)34)31-39(36,37)18-11-30-21-32(16-8-14(24)7-15(25)9-16)20(35)22(2,33(18)21)10-13-3-5-17(6-4-13)38-23(26,27)28/h3-9,11-12,31H,10H2,1-2H3,(H2,29,34)/t12-,22+/m0/s1
InChIKey: QSNSVPRLHYSSQG-AMXDTQDGSA-N

Cross-matching ID

PubChem CID: 10348691
CAS Number: 688756-00-5
TTD ID: D01WQO

References

1	Small molecules, big targets: drug discovery faces the protein-protein interaction challenge.Nat Rev Drug Discov. 2016 Aug;15(8):533-50.