Details of the Drug

General Information of Drug (ID: DMUCNB3)

Drug Name
remodelin
Synonyms
Remodelin; 949912-58-7; CHEMBL399572; GTPL8102; SCHEMBL17144586; MolPort-039-052-199; EX-A1315; BCP11087; ZINC28951699; BDBM50326653; AKOS025293490; CS-3458; HY-16706; KB-334022; 4-[2-(2-Cyclopentylidenehydrazinyl)-4-thiazolyl]benzonitrile; 4-(2-(2-cyclopentylidenehydrazinyl)thiazol-4-yl)benzonitrile; 4-[2-(2-cyclopentylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
Chemical Identifiers
Formula
C15H14N4S
Canonical SMILES
C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)C#N)C1
InChI
1S/C15H14N4S/c16-9-11-5-7-12(8-6-11)14-10-20-15(17-14)19-18-13-3-1-2-4-13/h5-8,10H,1-4H2,(H,17,19)
InChIKey
XAEJIFARBQJLML-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
44442376
TTD ID
D0IA3U

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-26 GDSC2 6.5763 13.2587 2.5829 15.9968
KYSE-50 GDSC2 6.7286 11.7892 3.4217 11.0226
ESO-51 GDSC2 6.974 14.9949 2.0253 17.6993
OACM5.1 C GDSC2 7.0685 9.4121 4.7728 2.4986
OACP4 C GDSC2 8.1523 16.4302 2.171 14.3217
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB1 GDSC2 3.7384 8.1681 2.5791 25.3953
CHP-134 GDSC2 4.7571 9.4533 2.9576 19.4701
CHP-212 GDSC2 4.9066 8.6284 3.5001 15.8075
SK-N-DZ GDSC2 5.7565 8.6505 4.2334 8.6021
SK-N-BE(2)-M17 GDSC2 6.0151 10.1333 3.7005 11.1913
NB(TU)1 GDSC2 6.3787 8.523 4.761 3.7792
GOTO GDSC2 6.4283 10.9054 3.6348 10.5096
SiMa GDSC2 6.4751 11.9457 3.156 13.1692
IMR-5 GDSC2 6.6395 11.4603 3.5179 10.6791
NH-12 GDSC2 6.8406 14.8898 1.9764 18.2587
GI-ME-N GDSC2 8.2288 11.4059 4.5254 2.2428
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CADO-ES1 GDSC2 4.921 9.2175 3.2239 17.3884
TC-71 GDSC2 4.9746 8.665 3.5448 15.3067
EW-1 GDSC2 5.0137 9.233 3.3004 16.6285
NOS-1 [Human HNSCC] GDSC2 5.4319 10.2707 3.1515 16.1458
ES4 GDSC2 6.3028 10.4707 3.7552 10.1034
CAL-78 GDSC2 6.3472 8.4678 4.7663 3.813
HuO9 GDSC2 6.5579 12.1382 3.1234 13.1409
EW-16 GDSC2 6.8561 13.4726 2.6881 14.7421
MHH-ES-1 GDSC2 6.9548 15.6012 1.711 19.1521
SK-ES-1 GDSC2 7.0319 10.2465 4.3709 4.7989
CHSA8926 GDSC2 7.0372 9.05 4.9139 1.8164
U2OS GDSC2 7.3533 15.93 1.8466 17.5856
HuO-3N1 GDSC2 7.417 10.4488 4.5087 3.379
EW-18 GDSC2 7.5018 13.4822 3.1441 10.8184
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BT-20 GDSC2 3.9879 6.768 3.4414 19.6357
HCC1500 GDSC2 4.4874 10.9788 1.9605 25.4499
DU4475 GDSC2 4.5267 7.4592 3.6942 16.0116
HCC1954 GDSC2 4.9688 11.5768 2.0977 23.1513
HCC1419 GDSC2 4.9729 11.0133 2.3813 21.7709
BT-474 GDSC2 5.0438 11.9808 1.9624 23.5235
Evsa-T GDSC2 5.1432 7.4982 4.2723 10.2566
MDA-MB-361 GDSC2 5.555 8.0676 4.3572 8.4062
COLO 824 GDSC2 5.7878 12.4561 2.357 19.326
MCF-7 GDSC2 5.8533 11.7993 2.7389 17.1675
HCC2157 GDSC2 6.0387 12.6165 2.4809 17.9785
CAL-51 GDSC2 6.0764 10.9616 3.3363 13.1936
AU565 GDSC2 6.1628 8.4835 4.6299 5.0587
T-47D GDSC2 6.2469 12.1865 2.8605 15.4071
HCC1143 GDSC2 6.4481 10.592 3.8039 9.4474
HDQ-P1 GDSC2 6.6459 15.3681 1.5895 20.4624
HCC1937 GDSC2 6.7591 11.7938 3.4415 10.835
HCC1428 GDSC2 6.7919 12.4653 3.1361 12.4876
MFM-223 GDSC2 6.9802 9.2725 4.7851 2.5659
HCC1187 GDSC2 7.032 17.2702 0.9431 22.0424
CAL-120 GDSC2 7.35 15.727 1.9439 17.1575
EFM-192A GDSC2 7.5716 16.0311 1.956 16.5854
JIMT-1 GDSC2 7.7022 16.6578 1.7438 17.2265
HCC1806 GDSC2 8.2511 9.6963 5.1817 0.1242
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GB-1 GDSC2 5.5681 11.4994 2.6527 18.4737
LN-405 GDSC2 5.736 10.2299 3.4272 13.6196
LN-18 GDSC2 6.2149 13.1817 2.3396 18.1918
CAS-1 GDSC2 6.2288 11.2956 3.2895 13.0533
DK-MG GDSC2 6.2775 9.0993 4.4115 6.139
AM-38 GDSC2 6.2871 9.4189 4.2619 7.0394
A-172 GDSC2 6.3223 9.6794 4.1598 7.5837
U-251MG GDSC2 6.5766 10.2347 4.0717 7.5238
Daoy GDSC2 6.7036 12.6179 2.9958 13.4802
SF268 GDSC2 6.7678 9.9018 4.363 5.3593
DBTRG-05MG GDSC2 6.8328 11.5927 3.5926 9.7856
SK-MG-1 GDSC2 7.0263 15.8891 1.6228 19.3529
U-87MG ATCC GDSC2 7.1246 10.5529 4.2863 5.1134
8-MG-BA GDSC2 7.3604 11.9931 3.7605 7.6768
U-118MG GDSC2 7.5928 9.2802 5.0818 0.5861
42-MG-BA GDSC2 7.7195 16.2882 1.9367 16.3354
LN-229 GDSC2 8.5584 16.3552 2.4788 12.0486
PFSK-1 GDSC2 8.592 21.1288 0.1997 21.1193
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC2 5.9209 11.2707 3.0579 15.2239
ETK-1 GDSC2 6.4867 9.0273 4.5925 4.567
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 GDSC2 5.7293 13.2514 1.911 21.6099
MFE-319 GDSC2 5.8099 10.8549 3.1754 14.8749
KLE GDSC2 5.8852 10.152 3.5876 12.2331
AN3-CA GDSC2 5.959 9.5802 3.9318 9.9254
MFE-296 GDSC2 5.9711 10.8262 3.3201 13.5789
Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MM1.S GDSC2 3.2279 7.3479 2.4045 28.4931
MHH-CALL-2 GDSC2 3.9407 6.875 3.348 20.3648
EJM GDSC2 4.3045 7.9354 3.2532 19.4514
KMS-12-BM GDSC2 4.3413 8.369 3.0866 20.2611
ATN-1 GDSC2 4.4344 10.6365 2.0797 25.1015
697 GDSC2 4.801 7.3102 4.0348 12.9318
ALL-PO GDSC2 4.8151 8.6245 3.4168 16.6212
Karpas-45 GDSC2 5.0673 13.6268 1.1623 26.7343
P30/OHK GDSC2 5.0793 11.1185 2.4229 21.2086
CTV-1 GDSC2 5.1217 11.343 2.3482 21.4414
MOLM-13 GDSC2 5.1238 8.9049 3.562 14.7043
SU-DHL-5 GDSC2 5.1723 11.2189 2.4542 20.746
HL-60 GDSC2 5.2053 9.2631 3.4569 15.0703
KE-37 GDSC2 5.29 8.0993 4.1101 10.7841
OCI-M1 GDSC2 5.3124 8.0775 4.1409 10.5195
KG-1 GDSC2 5.3549 10.3999 3.0209 17.1287
A3/Kawakami GDSC2 5.4736 6.9846 4.8267 5.6909
BALL-1 GDSC2 5.4736 10.5769 3.0341 16.6846
Jurkat GDSC2 5.4778 13.9177 1.3677 24.6656
RPMI-8866 GDSC2 5.4986 12.3333 2.1773 21.0729
RS4;11 GDSC2 5.5362 10.2574 3.2468 15.2747
MOLP-8 GDSC2 5.6527 9.3608 3.7928 11.6483
ARH-77 GDSC2 5.6736 7.3459 4.8175 5.1465
P32/ISH GDSC2 5.6943 9.1248 3.9452 10.5833
MHH-PREB-1 GDSC2 5.7084 11.3808 2.829 17.1087
PF-382 GDSC2 5.7274 8.5543 4.2577 8.5312
JSC-1 GDSC2 5.7361 9.5714 3.7564 11.6297
MOLT-13 GDSC2 5.7552 8.3514 4.3817 7.6714
Granta-519 GDSC2 5.76 8.3639 4.3794 7.6719
MOLT-16 GDSC2 5.7677 10.4538 3.3413 14.0349
OCI-AML-5 GDSC2 5.8043 15.2894 0.9542 25.2666
JJN-3 GDSC2 5.8114 12.1694 2.5196 18.4366
GA-10 GDSC2 5.8305 8.6712 4.2827 8.0854
KM-H2 GDSC2 5.8479 8.2861 4.4887 6.7404
RPMI-8226 GDSC2 5.8574 12.7214 2.2815 19.4932
Karpas-231 GDSC2 5.8829 8.7624 4.2791 7.9653
EM-2 GDSC2 5.8962 9.3186 4.0123 9.5974
SU-DHL-10 GDSC2 5.9003 9.2708 4.0394 9.4175
P12-Ichikawa GDSC2 5.928 10.9163 3.2406 14.1621
CESS GDSC2 5.9281 8.1301 4.6289 5.6455
SUP-M2 GDSC2 5.9324 11.4465 2.9794 15.6298
TUR GDSC2 5.9532 12.7718 2.3343 18.9562
DG-75 GDSC2 6.0129 9.9423 3.7939 10.6278
KCL-22 GDSC2 6.0267 11.9078 2.8249 16.2091
TK [Human B-cell lymphoma] GDSC2 6.0349 8.3323 4.6099 5.4931
JVM-2 GDSC2 6.0555 8.6448 4.4711 6.3096
GDM-1 GDSC2 6.1041 11.8498 2.9155 15.4993
RC-K8 GDSC2 6.1101 10.9473 3.37 12.9045
KOPN-8 GDSC2 6.1219 10.0147 3.8429 10.0375
ALL-SIL GDSC2 6.148 10.7845 3.4807 12.1509
BV-173 GDSC2 6.3431 8.3141 4.8369 3.3983
CA46 GDSC2 6.3541 10.9567 3.5536 11.1792
JURL-MK1 GDSC2 6.371 13.5357 2.2864 18.026
Daudi GDSC2 6.4199 8.8039 4.6544 4.3346
H9 GDSC2 6.5097 11.633 3.3367 12.0515
SU-DHL-8 GDSC2 6.5515 8.3723 4.9413 2.3992
KMOE-2 GDSC2 6.6375 11.045 3.7199 9.4935
HC-1 GDSC2 6.7649 14.615 2.0549 18.0904
SCC-3 GDSC2 6.8393 9.7659 4.4736 4.5666
L-428 GDSC2 6.9883 15.144 1.9624 17.9516
Hs 445 GDSC2 7.145 11.1405 4.0233 6.5956
Jiyoye GDSC2 7.2167 11.7861 3.764 7.9501
SUP-HD1 GDSC2 7.348 9.3774 4.9334 1.3598
Raji GDSC2 7.7322 9.0521 5.2183 0.1835
SUP-B15 GDSC2 7.8606 9.6958 5.0361 0.5699
KY821 GDSC2 8.7858 27.4226 -2.7508 28.2319
DEL GDSC2 10.5585 28.792 -2.1343 23.8403
⏷ Show the Full List of 67 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMRC-20 GDSC2 5.2674 7.862 4.2073 10.2492
LB996-RCC GDSC2 6.0394 10.749 3.413 12.8453
A-498 GDSC2 6.3531 15.4294 1.3289 22.3111
786-O GDSC2 6.5264 11.7804 3.2764 12.3554
BFTC-909 GDSC2 6.8651 13.973 2.4481 15.9422
A-704 GDSC2 6.8987 13.375 2.7677 14.2208
RCC10RGB GDSC2 7.4315 12.1047 3.7541 7.5714
OS-RC-2 GDSC2 8.1484 15.3404 2.6904 11.8287
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
C2BBe1 GDSC2 4.4568 10.3986 2.2169 24.3782
SNU-175 GDSC2 4.4892 9.0788 2.8896 20.8071
CL-11 GDSC2 4.7288 18.0492 -1.3369 34.5996
SNU-407 GDSC2 4.8041 8.5177 3.4586 16.4114
GP5d GDSC2 5.37 10.9603 2.7541 18.5487
LS411N GDSC2 5.9283 11.3671 3.0156 15.4398
SW620 GDSC2 6.1976 13.5141 2.1602 19.109
DiFi GDSC2 6.2995 10.1621 3.9052 9.2009
SW626 GDSC2 6.412 10.8839 3.6332 10.5598
NCI-H747 GDSC2 6.455 13.9004 2.1706 18.3576
HT-29 GDSC2 6.4704 13.2197 2.5208 16.592
SNU-C5 GDSC2 6.5689 9.645 4.3519 5.8439
MDST8 GDSC2 6.6098 9.6778 4.364 5.6822
HCC2998 GDSC2 6.7751 13.4553 2.6362 15.2135
HT-55 GDSC2 6.794 14.4447 2.1614 17.5165
NCI-H716 GDSC2 6.8772 12.0736 3.3899 10.8525
COLO 678 GDSC2 6.88 12.3264 3.2684 11.5351
COLO205 GDSC2 6.9323 14.4285 2.2736 16.631
KM12 GDSC2 6.9567 13.8069 2.5981 14.958
SNU-C2B GDSC2 7.5253 15.1657 2.3452 14.8709
HCT 15 GDSC2 7.5418 13.2346 3.29 9.9392
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep-G2/C3A GDSC2 3.7449 6.8432 3.1544 22.2808
SNU-398 GDSC2 4.7331 9.153 3.0824 18.8525
Huh-7 GDSC2 4.9276 9.2342 3.2217 17.379
JHH-4 GDSC2 5.043 9.9781 2.9577 18.4929
HuH-1 GDSC2 5.6328 9.2756 3.8187 11.5469
JHH-1 GDSC2 5.6407 10.9708 2.9778 16.4916
JHH-6 GDSC2 6.3266 9.6657 4.1697 7.5128
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 64 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H23 GDSC2 3.2318 6.2647 2.8192 26.3715
DMS 53 GDSC2 4.0743 7.7336 3.1146 21.1424
NCI-H1944 GDSC2 4.1408 8.3821 2.8836 22.1604
NCI-H1688 GDSC2 4.3251 7.4332 3.5037 17.9139
NCI-H1573 GDSC2 4.716 9.948 2.6768 21.1384
DMS 273 GDSC2 4.9481 9.6846 3.0179 18.4742
A-549 GDSC2 5.1248 11.1411 2.4515 20.9148
NCI-H1092 GDSC2 5.1446 7.3313 4.355 9.7373
NCI-H720 GDSC2 5.4308 8.4816 4.0437 10.7559
HCC15 GDSC2 5.5321 11.7427 2.5008 19.3715
UMC-11 GDSC2 5.5365 10.5148 3.1184 16.0136
NCI-H1155 GDSC2 5.6253 10.1576 3.3715 14.2753
Lu-135 GDSC2 5.6419 8.1499 4.3892 7.9474
SBC-5 GDSC2 5.705 10.0672 3.4829 13.3782
NCI-H1793 GDSC2 5.7055 7.7165 4.6584 6.0624
NCI-H1341 GDSC2 5.7099 11.4948 2.7732 17.4055
COR-L23 GDSC2 5.9134 11.9318 2.7216 17.0855
COR-L311 GDSC2 5.9285 9.9114 3.7424 11.1734
NCI-H1975 GDSC2 5.9324 10.4156 3.494 12.6617
NCI-H2347 GDSC2 5.9488 13.8131 1.8105 21.4169
NCI-H1048 GDSC2 5.9611 11.1197 3.1656 14.4991
LXF 289 GDSC2 6.0466 9.2597 4.1596 8.2776
NCI-H2228 GDSC2 6.1514 9.534 4.1039 8.3534
HOP-92 GDSC2 6.2379 12.4776 2.7086 16.2444
SW1573 GDSC2 6.2704 10.6351 3.6492 10.8244
NCI-H1781 GDSC2 6.2845 8.7454 4.5891 5.0288
NCI-H2405 GDSC2 6.3135 10.5357 3.7311 10.222
NCI-H2373 GDSC2 6.3173 9.3328 4.3261 6.5715
Calu-6 GDSC2 6.3422 9.2913 4.3643 6.2781
HCC827 GDSC2 6.4157 10.2421 3.952 8.6297
NCI-H2141 GDSC2 6.5644 9.8304 4.2592 6.4145
NCI-H196 GDSC2 6.6713 16.2898 1.151 22.1674
NCI-H2591 GDSC2 6.6947 13.193 2.7053 15.0577
LOU-NH91 GDSC2 6.6951 15.4063 1.6086 20.2537
NCI-H209 GDSC2 6.7627 18.9283 -0.0905 26.142
NCI-H1876 GDSC2 6.7802 14.0792 2.3317 16.7313
NCI-H1693 GDSC2 6.8797 11.0137 3.906 7.8378
PC-14 GDSC2 6.8976 15.7225 1.6075 19.7404
Lu-99A GDSC2 6.9239 13.2219 2.8615 13.6629
NCI-H650 GDSC2 6.9462 10.4311 4.2291 5.7901
NCI-H1568 GDSC2 6.9472 19.1784 -0.0703 25.6323
LCLC-97TM1 GDSC2 7.005 11.3121 3.8482 7.9072
SK-MES-1 GDSC2 7.0248 12.3272 3.3714 10.616
NCI-H1915 GDSC2 7.0882 8.9857 4.9677 1.4914
NCI-H513 GDSC2 7.1208 13.9248 2.6605 14.2415
RERF-LC-Sq1 GDSC2 7.1273 9.745 4.6578 3.0241
EBC-1 GDSC2 7.1806 16.7833 1.2972 20.316
NCI-H1623 GDSC2 7.1825 17.9188 0.7367 22.4249
NCI-H2722 GDSC2 7.195 11.4241 3.9217 7.084
NCI-H2122 GDSC2 7.3427 15.8823 1.8622 17.5409
NCI-H322M GDSC2 7.4222 9.9158 4.7446 2.158
NCI-H2369 GDSC2 7.4541 13.6693 3.0212 11.5836
NCI-H1563 GDSC2 7.568 17.1624 1.3989 18.9857
NCI-H1650 GDSC2 7.5729 10.0752 4.7543 1.9282
NCI-H446 GDSC2 7.6084 10.9457 4.3958 3.6889
EPLC-272H GDSC2 7.6808 13.1574 3.4188 8.9477
NCI-H596 GDSC2 7.7168 9.2288 5.1502 0.3315
HOP-62 GDSC2 7.744 17.2546 1.4821 18.2404
NCI-H1838 GDSC2 7.8237 14.0405 3.0937 10.4145
RERF-LC-KJ GDSC2 7.8943 16.4742 1.9702 15.7954
EMC-BAC-2 GDSC2 7.9553 14.1391 3.1336 9.9376
NCI-H661 GDSC2 8.0396 19.1676 0.7598 20.371
LC-1/sq GDSC2 8.1394 14.4518 3.1055 9.725
NCI-H2170 GDSC2 9.7657 19.2118 1.91 12.4017
⏷ Show the Full List of 64 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-6 GDSC2 5.9299 9.3529 4.022 9.4449
TE-4 GDSC2 6.0109 10.1313 3.6982 11.216
OE19 GDSC2 6.2322 8.6217 4.6122 5.0065
KYSE-140 GDSC2 6.4836 10.4442 3.9025 8.7658
KYSE-150 GDSC2 6.556 9.5826 4.3731 5.7436
TE-1 GDSC2 6.5943 10.9419 3.7392 9.4816
KYSE-520 GDSC2 6.8474 9.2369 4.7237 3.1171
EC-GI-10 GDSC2 6.9783 9.8558 4.5188 4.0477
KYSE-180 GDSC2 7.0351 11.4138 3.8198 8.0085
KYSE-410 GDSC2 7.2188 10.6192 4.3141 4.7824
OE21 GDSC2 7.4361 10.2324 4.6149 2.7927
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OAW28 GDSC2 5.1552 7.9377 4.068 11.4882
OVCAR-4 GDSC2 5.2952 12.9852 1.6787 23.9558
TOV-112D GDSC2 5.5896 8.1543 4.3431 8.3925
OV56 GDSC2 5.6107 7.5021 4.6869 6.1558
TOV-21G GDSC2 6.5822 8.6207 4.8457 2.8882
OAW42 GDSC2 6.6004 12.6051 2.9247 14.1284
IGROV-1 GDSC2 6.6047 9.608 4.3941 5.5119
OVCAR-3 GDSC2 6.6547 11.3571 3.5796 10.2812
TYK-nu GDSC2 6.6599 10.5894 3.9582 8.0172
OVISE GDSC2 6.7151 12.8639 2.883 14.063
OVTOKO GDSC2 6.9693 9.8145 4.5323 3.987
OVCAR-8 GDSC2 7.1414 11.4804 3.8595 7.5543
ES-2 GDSC2 7.2599 10.149 4.5529 3.3843
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HPAC GDSC2 4.2381 8.7071 2.8263 22.095
SU.86.86 GDSC2 5.1495 8.1964 3.9354 12.3308
HuP-T4 GDSC2 5.4074 8.1375 4.1949 9.8804
PL4 GDSC2 6.0573 9.3977 4.0994 8.6242
SUIT-2 GDSC2 6.299 11.8161 3.0853 14.0277
DAN-G GDSC2 6.5116 8.7503 4.7406 3.6334
AsPC-1 GDSC2 6.587 12.272 3.0792 13.3135
HuP-T3 GDSC2 6.6523 9.7066 4.379 5.5022
PaTu 8902 GDSC2 6.6998 10.7283 3.9188 8.1624
CFPAC-1 GDSC2 6.8198 11.731 3.516 10.261
KP-1N GDSC2 6.8689 9.7654 4.4926 4.3997
PaTu 8988t GDSC2 7.0555 18.0896 0.5547 23.3678
Panc 08.13 GDSC2 7.6174 16.3461 1.835 17.0207
KP-2 GDSC2 8.2575 15.4235 2.7231 11.4471
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2052 GDSC2 7.2988 10.6891 4.3306 4.5483
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC2 3.7308 10.8983 1.291 31.0147
PC-3 GDSC2 6.434 12.1836 3.0069 14.1077
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 6.7722 9.6905 4.4659 4.742
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 792 GDSC2 3.3202 6.0865 2.9746 25.1413
A101D GDSC2 6.0798 8.8208 4.4024 6.6771
G-361 GDSC2 6.3824 11.7205 3.1969 13.178
A2058 GDSC2 6.4441 11.5763 3.3152 12.3421
RPMI-7951 GDSC2 6.5464 12.7626 2.8058 14.9068
A-375 GDSC2 6.9268 11.5432 3.6829 9.0454
M14 GDSC2 7.043 9.6628 4.6459 3.2237
WM278 GDSC2 7.0747 9.7322 4.6331 3.2427
WT2-iPS GDSC2 7.1467 11.5056 3.851 7.592
IGR-1 GDSC2 7.2483 14.6241 2.4105 15.196
Mel JuSo GDSC2 7.3297 12.5084 3.4946 9.2488
WM35 GDSC2 7.429 13.6647 3.0061 11.7194
WM793 GDSC2 7.522 9.1137 5.1151 0.5245
COLO 829 GDSC2 7.6383 9.6714 4.9504 1.0179
UACC-257 GDSC2 7.9998 15.2489 2.6345 12.4131
HT-144 GDSC2 8.4536 18.105 1.571 16.3306
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1080 GDSC2 3.9084 6.8854 3.3097 20.7177
G-402 GDSC2 4.6289 8.7415 3.185 18.6372
EW-8 GDSC2 5.6661 11.4513 2.7586 17.6146
Rh41 GDSC2 5.969 8.7543 4.3506 7.2862
MES-SA GDSC2 6.3777 9.9819 4.0519 8.112
VA-ES-BJ GDSC2 6.3899 11.1197 3.5001 11.4041
A-204 GDSC2 6.4471 14.4513 1.8903 19.6764
RD GDSC2 6.8667 13.9988 2.4366 15.9956
G-401 GDSC2 6.9314 11.984 3.4722 10.255
GCT GDSC2 7.3074 9.36 4.9208 1.4598
Rh30 GDSC2 7.5659 15.4877 2.2172 15.3906
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-5 GDSC2 4.5486 10.178 2.4099 23.1052
23132/87 GDSC2 5.3489 9.7455 3.3423 15.2933
HGC-27 GDSC2 5.3964 9.2699 3.6207 13.4763
AGS GDSC2 6.164 13.4661 2.1573 19.2159
NUGC-3 GDSC2 6.3575 10.2282 3.9159 8.9915
SK-GT-2 GDSC2 6.3713 14.1459 1.9828 19.461
IM95 GDSC2 6.67 10.1428 4.1815 6.6515
SNU-1 GDSC2 6.7105 13.2162 2.7057 15.0152
Hs 746.T GDSC2 7.0771 11.7663 3.6791 8.7365
NUGC-4 GDSC2 7.2233 10.7512 4.2557 5.1064
RERF-GC-1B GDSC2 7.7402 10.4577 4.6779 2.0914
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BHT-101 GDSC2 6.3507 12.584 2.7438 15.7526
8505C GDSC2 6.6982 11.7556 3.416 11.1288
HTC-C3 GDSC2 6.7087 13.4312 2.5981 15.5775
ASH-3 GDSC2 6.8678 13.2832 2.79 14.1794
B-CPAP GDSC2 7.1401 14.8991 2.1962 16.4911
TT2609-C02 GDSC2 7.5993 9.7492 4.9015 1.248
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-4 GDSC2 3.7067 6.8897 3.0952 22.7723
LB771-HNC GDSC2 4.0446 10.0619 1.9928 26.9629
CAL-27 GDSC2 5.3263 11.3915 2.5012 20.0121
CAL-33 GDSC2 5.3941 10.1941 3.1574 16.2294
Detroit 562 GDSC2 6.0387 12.3896 2.5941 17.3978
SKN-3 GDSC2 6.2202 10.201 3.826 9.8854
SAT [Human HNSCC] GDSC2 6.3902 15.6805 1.2331 22.589
BICR 10 GDSC2 6.6281 9.2744 4.5687 4.4196
SCC-15 GDSC2 6.6665 12.43 3.0608 13.2152
HSC-3 GDSC2 6.7227 10.3664 4.11 6.9655
UPCI-SCC-090 GDSC2 7.0594 11.1104 3.9812 7.0146
BB49-HNC GDSC2 7.0634 9.8301 4.5821 3.5436
OSC-20 GDSC2 7.0786 10.3254 4.3634 4.7556
FaDu GDSC2 10.6803 25.5904 -0.5087 19.4319
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RT-4 GDSC2 3.9241 7.2495 3.1736 21.4206
SW780 GDSC2 5.8222 8.9259 4.149 8.9481
639V GDSC2 6.0186 13.7563 1.8955 20.838
KU-19-19 GDSC2 6.373 10.5663 3.7608 9.8929
5637 GDSC2 6.4979 11.2803 3.5019 11.1212
TCCSUP GDSC2 6.6448 10.8964 3.7978 9.0126
CAL-29 GDSC2 6.6636 12.3991 3.0738 13.1504
J82 GDSC2 6.9024 14.4032 2.2637 16.7536
647V GDSC2 6.9884 10.8407 4.0624 6.6844
HT-1197 GDSC2 7.5563 17.0376 1.4516 18.7972
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-1 GDSC2 5.3671 10.0349 3.2136 15.9893
HT-3 GDSC2 5.5802 12.2415 2.2918 20.2696
SiHa GDSC2 5.7232 10.1536 3.4547 13.4932
BPH-1 GDSC2 5.8011 12.7714 2.2103 20.0033
OVCA420 GDSC2 5.9282 13.3278 2.0362 20.4548
PWR-1E GDSC2 5.9297 11.3521 3.0243 15.3874
MS751 GDSC2 6.1444 13.4406 2.1544 19.2848
HEY GDSC2 6.2615 10.6881 3.6161 11.0457
SW756 GDSC2 6.265 11.7999 3.067 14.2212
C-4-I GDSC2 6.5247 14.5719 1.891 19.4664
PA-1 GDSC2 6.5251 12.2687 3.0341 13.7213
SiSo GDSC2 6.8504 16.141 1.3638 20.869
NEC8 GDSC2 7.2698 11.316 4.0213 6.3621
HeLa GDSC2 8.1869 18.4265 1.228 18.2859
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug

References

1 Chemical inhibition of NAT10 corrects defects of laminopathic cells. Science. 2014 May 2;344(6183):527-32.