Details of the Drug

General Information of Drug (ID: DMUIQUK)

Drug Name
GS-5816
Indication
Disease Entry ICD 11 Status REF
Chronic HCV-1 infection 1E51.1 Phase 2 [1]
Structure
3D MOL is unavailable 2D MOL
Chemical Identifiers
Formula
C49H54N8O8
Canonical SMILES
CC1CCC(N1C(=O)C(C(C)C)NC(=O)OC)C2=NC3=C(N2)C=CC4=CC5=C(C=C43)OCC6=C5C=CC(=C6)C7=CN=C(N7)C8CC(CN8C(=O)C(C9=CC=CC=C9)NC(=O)OC)COC
InChI
InChI=1S/C49H54N8O8/c1-26(2)41(54-48(60)63-5)47(59)57-27(3)12-17-38(57)45-51-36-16-14-30-20-35-33-15-13-31(19-32(33)25-65-40(35)21-34(30)43(36)53-45)37-22-50-44(52-37)39-18-28(24-62-4)23-56(39)46(58)42(55-49(61)64-6)29-10-8-7-9-11-29/h7-11,13-16,19-22,26-28,38-39,41-42H,12,17-18,23-25H2,1-6H3,(H,50,52)(H,51,53)(H,54,60)(H,55,61)/t27-,28-,38-,39-,41-,42+/m0/s1
InChIKey
FHCUMDQMBHQXKK-CDIODLITSA-N
Cross-matching ID
PubChem CID
67683363
ChEBI ID
CHEMBL133009
CAS Number
1377049-84-7
TTD ID
D09KTI
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Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

References

1 ClinicalTrials.gov (NCT02336139) A Phase II Trial of Sofosbuvir (SOF) and GS-5816 for People With Chronic Hepatitis C Virus Infection and Recent Injection Drug Use. U.S. National Institutes of Health.