Details of the Drug

General Information of Drug (ID: DMUKC5L)

Drug Name
Tivozanib
Synonyms ASP4130/AV-951
Indication
Disease Entry ICD 11 Status REF
Renal cell carcinoma 2C90 Approved [1]
ATC Code
L01EK03: Tivozanib
L01EK: Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors
L01E: PROTEIN KINASE INHIBITORS
L01: ANTINEOPLASTIC AGENTS
L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 454.9
Logarithm of the Partition Coefficient (xlogp) 4
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 7
ADMET Property
Absorption AUC
The area under the plot of plasma concentration (AUC) of drug is 1084 +/- 417.0 mcgh/L [2]
Absorption Cmax
The maximum plasma concentration (Cmax) of drug is 12.1 +/- 5.67 mcg/L [2]
Absorption Tmax
The time to maximum plasma concentration (Tmax) is 10 h [2]
Clearance
The clearance of drug is 0.75 L/h [2]
Elimination
After oral ingestion of a radiolabeled 1.34 mg dose of tivozanib in healthy volunteers, 79% of the administered dose was found in the feces (with 26% unchanged) and 12% was found in the urine solely as metabolites [3]
Half-life
The concentration or amount of drug in body reduced by one-half in 111 hours [2]
Metabolism
The drug is metabolized via the CYP3A4 [2]
Vd
The volume of distribution (Vd) of drug is 123 L [2]
Chemical Identifiers
Formula
C22H19ClN4O5
IUPAC Name
1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(5-methyl-1,2-oxazol-3-yl)urea
Canonical SMILES
CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl
InChI
InChI=1S/C22H19ClN4O5/c1-12-8-21(27-32-12)26-22(28)25-16-5-4-13(9-15(16)23)31-18-6-7-24-17-11-20(30-3)19(29-2)10-14(17)18/h4-11H,1-3H3,(H2,25,26,27,28)
InChIKey
SPMVMDHWKHCIDT-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
9911830
ChEBI ID
CHEBI:91327
CAS Number
475108-18-0
UNII
172030934T
DrugBank ID
DB11800
TTD ID
D0W7JZ
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Vascular endothelial growth factor receptor 1 (FLT-1) TT2Q6G1 VGFR1_HUMAN Inhibitor [1]
Vascular endothelial growth factor receptor 2 (KDR) TTUTJGQ VGFR2_HUMAN Modulator [1]
Vascular endothelial growth factor receptor 3 (FLT-4) TTDCBX5 VGFR3_HUMAN Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Renal cell carcinoma
ICD Disease Classification 2C90
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Vascular endothelial growth factor receptor 2 (KDR) DTT KDR 1.98E-01 0.11 0.2
Vascular endothelial growth factor receptor 3 (FLT-4) DTT FLT4 6.00E-01 -0.04 -0.23
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 0.0662 4.129 -4.4187 4.0398
ES1 GDSC1 -2.2858 1.4166 -4.6193 10.6541
HuO9 GDSC1 -2.2197 5.036 -6.3632 21.3892
ES7 GDSC1 -0.7434 7.2258 -6.3494 17.0017
NOS-1 [Human HNSCC] GDSC1 -0.5967 8.6747 -6.9493 19.47
ES8 GDSC1 -0.2111 2.6992 -3.9641 1.9445
EW-13 GDSC1 -0.1273 2.704 -3.9283 1.6846
CHSA0108 GDSC1 0.0718 3.003 -3.9572 1.6245
EW-3 GDSC1 0.2049 5.3105 -4.8558 6.3725
CHSA8926 GDSC1 0.2469 3.0553 -3.9025 1.2417
CADO-ES1 GDSC1 0.248 6.1266 -5.1952 8.2936
HuO-3N1 GDSC1 0.2905 7.2514 -5.683 10.9934
EW-16 GDSC1 0.3019 4.5334 -4.4695 3.982
EW-1 GDSC1 0.3372 2.3865 -3.6256 0.3328
TC-71 GDSC1 0.3674 2.3791 -3.6123 0.2963
CAL-72 GDSC1 0.4384 2.1789 -3.5202 0.1338
EW-7 GDSC1 0.4478 2.8213 -3.7372 0.5606
CHSA0011 GDSC1 0.5032 5.5375 -4.7931 5.5043
ES5 GDSC1 0.5833 3.7136 -4.0111 1.4116
ES6 GDSC1 0.6139 3.1613 -3.7955 0.6457
EW-24 GDSC1 0.6426 2.1765 -3.4516 0.0495
EW-18 GDSC1 0.6466 3.3389 -3.8468 0.7817
H-EMC-SS GDSC1 0.6499 5.4699 -4.6878 4.688
EW-11 GDSC1 0.6749 3.8638 -4.0296 1.4135
SK-PN-DW GDSC1 0.6899 3.1569 -3.7655 0.5304
NY GDSC1 0.9854 3.2494 -3.6911 0.2752
ES4 GDSC1 1.063 3.5206 -3.7562 0.3759
SK-N-MC CTRP2 2.0718 4.4437 1.6764 12.3345
MG-63 GDSC1; CTRP2 2.54 7.3471 0.8382 14.5045
A-673 GDSC1; CTRP2 2.8183 4.4659 2.458 7.2476
U2OS GDSC1; CTRP2; CTRP1 2.9259 4.8772 2.7781 13.7911
CAL-78 GDSC1; CTRP2 3.1397 5.1602 2.933 12.5786
SK-ES-1 GDSC1; CTRP2 3.1641 5.2653 2.928 12.527
HOS GDSC1; CTRP2 3.3791 7.0459 1.753 8.8603
MHH-ES-1 GDSC1; CTRP2 3.4754 5.3547 3.2383 10.5918
TC71 CTRP2 3.4824 4.2776 3.2148 2.515
SW1353 CTRP2 4.3446 5.7977 3.4361 2.4352
SaOS-2 GDSC1; CTRP2 4.3463 7.1526 3.3639 8.0041
SJSA-1 GDSC1; CTRP2 5.0381 11.2188 1.952 12.1387
Hs 888.T CTRP2 5.1043 12.4906 1.3711 15.0735
Hs 822.T CTRP2 6.0091 8.584 3.9995 2.8417
G-292 clone A141B1 GDSC1; CTRP2 6.8449 12.9146 2.49 7.2097
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 210 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -3.6987 1.7764 -3.8436 68.5286
MEC1 CTRP2 2.3975 4.7772 1.8881 10.6158
JM1 GDSC1; CTRP2 1.5017 5.1459 0.795 17.3127
EoL-1 GDSC1; CTRP2 -12.5024 -4.681 -12.5767 87.564
Kasumi-1 GDSC1; CTRP2 -8.004 0.8152 -8.4167 69.8076
MY-M12 GDSC1 -5.7512 -2.3718 -6.1863 37.092
ALL-SIL GDSC1; CTRP2 -4.96 -2.0063 -4.9616 62.3969
MEG-01 GDSC1 -4.2815 -1.6013 -4.9144 20.8463
JURL-MK1 GDSC1; CTRP2 -3.537 -1.2697 -3.5375 53.5961
NCO2 CTRP2 -3.3456 -0.7226 -3.3477 55.8713
EM-2 GDSC1; CTRP2 -3.2127 0.7158 -3.2476 51.5383
LAMA-84 GDSC1; CTRP2 -2.9532 -0.6364 -2.9543 49.9535
K-562 GDSC1; CTRP2 -2.8266 1.3278 -2.9427 43.9002
Ku812 GDSC1; CTRP2; CTRP1 -2.7512 -1.3989 -2.7512 48.7379
SU-DHL-16 GDSC1 -2.4589 -0.2531 -3.9264 5.9234
KYO-1 CTRP2 -2.2021 -0.1431 -2.2029 60.3805
MOLM-6 CTRP2 -2.0714 1.5199 -2.1129 58.838
CML-T1 CTRP2 -2.0611 -0.2602 -2.0614 47.3387
BV-173 GDSC1; CTRP2 -1.9874 1.9734 -2.0589 44.069
EB2 GDSC1 -1.8164 2.4737 -4.7974 10.5517
KCL-22 GDSC1; CTRP2 -0.9265 2.1263 -0.9638 37.4052
BE-13 GDSC1 -0.5791 4.811 -5.0908 9.39
MOLM-13 GDSC1; CTRP2 -0.548 3.6536 -0.743 35.5036
Karpas-231 GDSC1 -0.4814 10.0056 -7.5157 21.5354
Pfeiffer CTRP2 -0.4074 2.4354 -0.5112 27.8246
CTV-1 GDSC1 -0.3437 2.7732 -4.0566 2.5836
JSC-1 GDSC1 -0.3291 2.6087 -3.9825 2.1718
WIL2 NS GDSC1 -0.3254 7.079 -5.9949 14.0942
MV4-11 GDSC1; CTRP2 -0.1824 3.76 -0.3674 33.212
YT GDSC1 -0.18 1.7871 -3.606 0.4874
SCC-3 GDSC1 -0.1726 1.133 -3.3804 0.0672
MLMA GDSC1 -0.1663 3.4633 -4.2559 3.4515
Namalwa GDSC1 -0.1543 2.8736 -4.0078 2.0987
ARH-77 GDSC1 -0.1173 2.8301 -3.9735 1.8893
RPMI-8866 GDSC1 -0.0936 2.0405 -3.6639 0.6149
P32/ISH GDSC1 -0.0577 1.6997 -3.5307 0.2601
KOPN-8 GDSC1 -0.0557 3.0809 -4.0453 2.1755
LC4-1 GDSC1 -0.0476 4.1015 -4.466 4.4897
TK [Human B-cell lymphoma] GDSC1 -0.0378 2.8022 -3.9271 1.5922
ME1 GDSC1 -0.0206 1.2171 -3.3577 0.0376
ATN-1 GDSC1 0.001 2.0381 -3.6271 0.463
QIMR-WIL GDSC1 0.001 5.488 -5.051 7.9211
Farage GDSC1 0.0981 3.3001 -4.0623 2.0901
P30/OHK GDSC1 0.1142 4.2069 -4.4271 4.0164
Hs 445 GDSC1 0.1223 2.7971 -3.8568 1.1572
Loucy GDSC1 0.1258 2.2463 -3.6541 0.4802
GR-ST GDSC1 0.1335 2.682 -3.8092 0.9679
MN-60 GDSC1 0.1372 3.2696 -4.0326 1.9072
NB4 GDSC1 0.146 2.4723 -3.7273 0.682
HC-1 GDSC1 0.1728 4.7482 -4.6279 5.0849
NKM-1 GDSC1 0.1853 8.5567 -6.3602 14.7929
MOLT-4 GDSC1 0.1956 2.9181 -3.872 1.161
SUP-B15 GDSC1; CTRP2 0.2036 7.9177 -1.7383 29.8848
WSU-NHL GDSC1 0.2107 2.2445 -3.6222 0.3681
DND-41 GDSC1 0.2233 4.2299 -4.3818 3.6066
BC-3 GDSC1 0.2359 2.3585 -3.6528 0.4311
Daudi GDSC1; CTRP2 0.2457 2.4721 0.1808 23.325
MHH-PREB-1 GDSC1 0.2682 2.2956 -3.6191 0.3414
CCRF-CEM GDSC1 0.2824 2.6688 -3.7455 0.6652
RC-K8 GDSC1 0.2929 2.1917 -3.5747 0.246
VAL GDSC1 0.2965 4.347 -4.3943 3.5742
HH [Human lymphoma] GDSC1 0.3215 5.8513 -5.0299 7.1874
TUR GDSC1 0.3465 2.7561 -3.7524 0.6525
Jiyoye GDSC1 0.351 2.2381 -3.5701 0.2234
BALL-1 GDSC1 0.3551 2.1111 -3.526 0.1554
Sc-1 GDSC1 0.4029 4.4346 -4.3784 3.347
Karpas-45 GDSC1 0.4076 2.7523 -3.7278 0.5533
BL-41 GDSC1 0.414 7.1834 -5.5769 10.1478
H9 GDSC1 0.4185 2.8581 -3.7614 0.6429
VL51 GDSC1 0.4198 4.7789 -4.5133 4.0564
A3/Kawakami GDSC1 0.4275 2.1773 -3.5234 0.1395
SUP-M2 GDSC1 0.4324 7.007 -5.4855 9.5984
PL-21 GDSC1 0.4477 2.9467 -3.7821 0.6892
U-698-M GDSC1 0.4592 2.2095 -3.5233 0.1343
CA46 GDSC1 0.4928 3.0163 -3.7898 0.6892
Ramos.2G6.4C10 GDSC1 0.5165 2.4054 -3.5691 0.1854
KG-1 GDSC1 0.5184 8.0562 -5.9147 11.772
HAL-01 GDSC1 0.5318 2.9227 -3.7417 0.5356
KY821 GDSC1 0.5493 2.2687 -3.5126 0.1089
CESS GDSC1 0.5502 2.54 -3.6028 0.2308
697 GDSC1 0.63 6.8662 -5.3071 8.2137
KMOE-2 GDSC1 0.6381 2.6245 -3.6008 0.2079
BC-1 GDSC1 0.656 3.8016 -4.014 1.3664
GDM-1 GDSC1; CTRP2; CTRP1 0.6936 4.6864 0.3912 28.2053
CTB-1 GDSC1 0.7485 9.5521 -6.4664 14.0775
ML-2 GDSC1 0.8152 2.7797 -3.592 0.1616
L-1236 GDSC1 0.8226 3.2025 -3.7328 0.4035
GA-10 CTRP2 0.8518 5.0877 0.127 21.6772
DG-75 GDSC1 0.9087 3.0477 -3.6496 0.2252
Mino CTRP2 0.9971 2.6904 0.9522 18.2318
DoHH2 CTRP2 1.0177 4.765 0.5306 23.6808
ROS-50 GDSC1 1.1116 3.7764 -3.8273 0.516
Peer CTRP2 1.2249 4.1312 1.0852 25.9218
ALL-PO GDSC1 1.3305 3.7751 -3.7486 0.2893
KO52 CTRP2 1.4531 3.7031 1.2471 15.7534
BL-70 CTRP2; CTRP1 1.4702 2.9082 1.4647 22.0186
Hs 611.T CTRP2 1.5791 6.807 0.1543 19.5824
EB1 CTRP2 1.5888 6.304 0.3907 18.6445
A4/Fukuda GDSC1; CTRP2 1.6892 3.7652 1.4875 14.1614
SEM CTRP2 1.7854 4.4458 1.6315 22.2401
KMS-34 CTRP2 2.2097 3.1593 2.2085 23.6428
JeKo-1 CTRP2 2.4202 5.2354 1.7132 11.2479
ST486 GDSC1; CTRP2 2.4677 3.4543 2.4135 8.4312
WSU-DLCL2 GDSC1; CTRP2; CTRP1 2.4815 7.5342 1.327 20.0922
JVM-2 GDSC1; CTRP2 2.4878 4.2919 2.4179 16.1918
Ri-1 CTRP2 2.4885 5.2176 2.2059 19.3081
SU-DHL-6 GDSC1; CTRP2 2.5261 4.4926 2.4247 16.0553
NALM-6 GDSC1; CTRP2 2.6293 3.8463 2.6153 15.1287
HuNS1 CTRP2 2.6469 5.9578 1.6069 11.1111
DB GDSC1; CTRP2 2.6746 4.1145 2.4457 7.6925
PF-382 GDSC1; CTRP2 2.7112 4.5503 2.614 14.8857
DEL GDSC1; CTRP2 2.7276 3.8808 2.7151 14.51
SIG-M5 GDSC1; CTRP2 2.7641 3.8437 2.6361 6.718
KMS-11 GDSC1; CTRP2; CTRP1 2.7657 6.4072 2.0923 16.6207
Ki-JK CTRP2 2.7978 4.8226 2.4282 10.6227
KE-37 GDSC1; CTRP2 2.7991 3.4811 2.7986 14.0258
RS4;11 GDSC1; CTRP2 2.8199 4.6727 2.7072 14.2579
KMS-21-BM CTRP2 2.8436 5.2249 2.591 15.5523
TF-1 CTRP2 2.8558 4.0578 2.6613 6.3568
SU-DHL-4 GDSC1; CTRP2; CTRP1 2.87 5.2395 2.6185 14.4899
JVM-3 GDSC1; CTRP2 2.8777 6.9335 1.9891 16.633
AML-193 CTRP2 2.8832 4.615 2.7877 14.726
RPMI-8402 GDSC1; CTRP2 2.8956 4.0317 2.8797 13.4714
MOTN-1 CTRP2 2.8975 3.8972 2.7635 5.8512
P31/FUJ GDSC1; CTRP2 2.9423 4.456 2.88 13.3286
KE-97 CTRP2; CTRP1 2.9654 4.9678 2.7985 14.5144
KMS-26 CTRP2 3.0028 4.4117 2.9518 13.7748
Granta-519 GDSC1; CTRP2 3.022 7.1197 1.397 11.1132
RPMI-6666 GDSC1; CTRP2 3.0268 8.1671 0.8836 13.2242
Mono-Mac-6 GDSC1; CTRP2 3.0269 6.7999 2.2009 15.4852
RL GDSC1; CTRP2 3.0285 5.4158 2.234 7.6257
OCI-AML-5 GDSC1; CTRP2 3.0516 4.1583 3.0327 12.5068
OPM-2 GDSC1; CTRP2 3.069 4.6189 2.6477 5.8392
SUP-T11 CTRP2 3.1273 4.6112 3.0526 16.3061
OCI-Ly3 CTRP2 3.1354 4.5495 2.7461 5.2746
SKM-1 CTRP2; CTRP1 3.1551 4.6536 3.0762 12.9415
SUP-T1 GDSC1; CTRP2 3.1712 5.974 2.6879 13.3513
Reh GDSC1; CTRP2 3.1746 4.3818 3.1392 11.7912
NU-DUL-1 GDSC1; CTRP2; CTRP1 3.2057 4.4943 3.158 11.7163
OCI-Ly19 GDSC1; CTRP2 3.2517 4.1639 3.0367 3.8121
HD-MY-Z CTRP2 3.2662 5.5237 2.4057 6.3675
OCI-M1 GDSC1; CTRP2 3.2824 3.8881 3.1821 3.1615
HEL 92.1.7 CTRP2 3.2899 3.9571 3.1633 3.2126
Mono-Mac-1 CTRP2 3.3151 5.7873 2.9127 16.2461
SU-DHL-8 GDSC1; CTRP2 3.3479 5.9715 2.8773 12.21
P12-Ichikawa GDSC1; CTRP2 3.3648 4.3573 3.3433 10.5587
TALL-1 [Human adult T-ALL] CTRP2 3.3791 4.8476 3.2767 14.3294
KM-H2 GDSC1; CTRP2 3.3796 6.5844 2.6591 12.9229
Jurkat CTRP2 3.385 5.1846 3.1933 15.993
Kasumi-2 CTRP2 3.3986 6.6239 2.6619 13.7222
MOLP-8 GDSC1; CTRP2 3.4238 5.3511 2.6346 5.0637
OCI-AML-2 GDSC1; CTRP2 3.4645 4.0548 3.463 9.8729
L-540 GDSC1; CTRP2 3.4696 5.3606 3.23 10.6363
SU-DHL-5 GDSC1; CTRP1 3.5572 4.7462 3.4936 9.5754
HL-60 GDSC1; CTRP2 3.5676 4.2287 3.3188 1.8877
SU-DHL-1 GDSC1; CTRP2 3.5754 4.5101 3.5493 9.2583
LP-1 GDSC1; CTRP2; CTRP1 3.5887 6.4125 2.9552 11.1923
KMS-12-BM GDSC1; CTRP2 3.5896 5.4678 3.3239 9.9808
SET-2 CTRP2 3.6407 4.6504 3.1748 2.3363
Karpas-422 GDSC1; CTRP2 3.6523 4.6116 3.2041 2.1894
RCH-ACV CTRP2 3.6888 5.0476 3.5642 11.8495
SUP-HD1 GDSC1; CTRP2 3.6942 7.3771 1.857 7.7892
NU-DHL-1 CTRP2 3.7268 8.424 2.1613 14.9032
MOLT-16 GDSC1; CTRP2 3.7386 4.4302 3.7288 8.1867
L-428 GDSC1; CTRP2 3.793 6.1821 3.2599 9.6832
OCI-AML-3 GDSC1; CTRP2; CTRP1 3.8256 4.8895 3.7551 7.785
KMS-28BM CTRP2 3.8312 5.0748 3.7119 10.64
KHM-1B CTRP2 3.8524 5.2738 3.6743 8.5753
KMS-18 CTRP2 3.8615 5.3608 3.655 10.7898
MOLM-16 CTRP2; CTRP1 3.8699 5.2675 3.6989 9.1284
REC-1 CTRP2 3.8838 5.2061 3.7302 10.3587
Karpas-620 GDSC1; CTRP2 3.8991 5.6694 3.5818 8.2416
EHEB CTRP2 3.9091 8.2044 1.8785 10.2794
MOLT-13 GDSC1; CTRP2 3.9374 5.1284 3.8124 7.3272
SK-MM-2 GDSC1; CTRP2 3.9512 4.8939 3.8888 7.0301
KMM-1 CTRP2 3.9584 6.0795 2.9819 5.2362
MM1.S CTRP2 4.0101 5.2134 3.8654 7.4045
PL21 CTRP2; CTRP1 4.0738 4.9631 4.0084 6.7827
HuT 78 CTRP2 4.0809 5.9598 3.6536 8.0186
Ci-1 CTRP2 4.0957 5.2524 3.224 1.3611
L-363 GDSC1; CTRP2 4.1217 5.9445 3.7024 7.2366
SU-DHL-10 GDSC1; CTRP2 4.1379 5.1951 4.0102 6.0873
ME1 CTRP2 4.1494 5.1973 4.022 6.4151
NCI-H929 CTRP2 4.2635 5.4812 4.043 6.0095
Raji GDSC1; CTRP2 4.3044 6.1371 3.8032 6.419
KMS-27 CTRP2 4.3085 6.5601 3.6109 7.6146
HPB-ALL CTRP2 4.4216 5.7603 4.0913 6.7549
Karpas-299 GDSC1; CTRP2 4.4373 6.6083 3.7128 6.4604
P3HR-1 CTRP2; CTRP1 4.449 6.5837 3.7433 8.5406
MC116 GDSC1; CTRP2; CTRP1 4.4634 5.0944 4.3989 3.9286
MHH-CALL-4 CTRP2 4.498 6.5595 3.7943 6.8718
KMS-20 CTRP2 4.502 7.2929 3.4414 7.8634
U-937 CTRP2; CTRP1 4.552 6.9796 3.6491 6.9757
HDLM-2 GDSC1; CTRP2 4.5711 6.5479 3.8692 5.5652
MHH-CALL-3 CTRP2 4.6463 6.0467 4.1823 4.4731
HT GDSC1; CTRP2; CTRP1 4.6487 6.2507 4.0942 4.6112
SR GDSC1; CTRP2 4.6753 6.2864 4.0942 4.4705
JJN-3 GDSC1; CTRP2 4.7335 8.1254 3.2377 7.7026
THP-1 GDSC1; CTRP2; CTRP1 4.7616 6.0247 4.3104 3.5325
RPMI-8226 GDSC1; CTRP2; CTRP1 4.7712 6.4089 4.1313 4.2077
CMK CTRP2 4.7937 6.6288 3.0157 1.3356
HEL GDSC1; CTRP2 4.8946 6.4114 4.2323 3.4819
F-36P CTRP2 4.9453 8.7696 3.0986 8.3702
NOMO-1 GDSC1; CTRP1 4.959 5.7788 4.6127 1.9461
EJM GDSC1; CTRP2; CTRP1 5.2223 7.171 4.1357 3.2912
AMO1 GDSC1; CTRP2; CTRP1 5.6203 6.6227 4.6805 0.7296
U266B1 GDSC1; CTRP2 6.0316 9.2378 3.7024 3.7463
MOLP-2 CTRP2 6.3032 8.803 4.0816 2.1659
OCI-Ly10 CTRP2; CTRP1 7.4265 9.6828 4.2972 0.5982
M-07e CTRP2 8.0531 17.4404 1.1391 11.0198
⏷ Show the Full List of 210 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 3.0894 6.3157 2.4667 15.3157
TE15 CTRP2 3.4638 5.2305 2.7302 4.5766
T.T GDSC1 0.2189 2.0805 -3.5629 0.244
OE33 GDSC1 0.3893 4.324 -4.3395 3.1585
TE-15 GDSC1 0.6792 2.8492 -3.6626 0.3042
KYSE-270 GDSC1 0.7365 2.646 -3.5743 0.1523
TE-8 GDSC1 0.9423 3.0427 -3.6364 0.1987
TE-11 GDSC1; CTRP2 2.8057 4.462 2.4466 7.3264
OE21 GDSC1; CTRP2 3.0531 4.5093 2.6811 5.7455
TE-5 GDSC1; CTRP2 3.1204 5.856 2.1079 7.9351
EC-GI-10 GDSC1; CTRP2 3.2639 6.123 2.1085 7.6137
TE-6 GDSC1; CTRP2 3.6815 6.1351 3.1636 10.316
TE-9 GDSC1; CTRP2 3.6917 5.7364 3.3348 9.6697
KYSE-450 GDSC1; CTRP2; CTRP1 3.8631 5.596 3.576 8.291
KYSE-410 GDSC1; CTRP2; CTRP1 3.9415 5.365 3.744 7.6358
KYSE-180 GDSC1; CTRP2 3.9608 6.0037 3.5102 8.3443
TE-10 GDSC1; CTRP2 4.4091 6.5545 3.7114 6.5282
TE-4 GDSC1; CTRP2 4.4115 6.2105 3.876 5.8943
TE-1 GDSC1; CTRP2 4.4889 7.6266 3.2655 8.0847
KYSE-140 GDSC1; CTRP2; CTRP1 4.5358 6.8165 3.7135 6.3253
KYSE-150 GDSC1; CTRP2 4.5927 7.4261 3.4589 7.1166
KYSE-510 GDSC1; CTRP2 4.7764 7.6195 3.5272 6.4821
KYSE-70 GDSC1; CTRP2 4.893 7.252 3.812 5.1376
KYSE-30 CTRP2 4.9821 7.3476 3.8405 5.1821
OE19 GDSC1; CTRP2 5.0407 8.2106 2.4405 3.2114
TE-14 CTRP2 5.1022 7.4764 3.8762 4.8
COLO 680N GDSC1; CTRP2 5.7649 11.7838 2.2547 9.7188
KYSE-520 GDSC1; CTRP2 5.9861 8.4615 2.8478 0.9307
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 5.0414 8.1362 2.4756 3.0743
Capan-1 GDSC1 0.362 2.5336 -3.6677 0.4188
PL4 GDSC1 0.5637 2.8397 -3.7008 0.4218
MZ-PC-1 GDSC1 0.8492 2.8571 -3.6062 0.1743
SW1990 GDSC1; CTRP2 2.5625 6.0318 1.4897 11.7941
MIA PaCa-2 GDSC1; CTRP2 3.0767 4.6599 2.6367 5.8639
KP-2 GDSC1; CTRP2 3.1202 4.1693 2.8978 4.71
DAN-G GDSC1; CTRP2 3.4129 4.8587 2.8671 4.116
HuP-T4 GDSC1; CTRP2; CTRP1 3.4309 5.5894 3.1136 11.2288
Panc 04.03 GDSC1; CTRP2 3.5875 5.7646 2.5728 4.9814
HuP-T3 GDSC1; CTRP2 3.663 5.202 2.9183 3.3736
PSN1 GDSC1; CTRP2 3.6781 5.8627 2.6007 4.6838
KP-4 GDSC1; CTRP2 3.7658 6.0702 3.2788 9.6821
HPAC GDSC1; CTRP2 3.7676 10.0666 1.4034 16.7345
SNU-213 CTRP2 3.7735 6.299 2.7102 6.8624
PaTu 8988s CTRP2 3.7755 4.7555 3.2341 1.827
L3.3 CTRP2 3.849 5.2661 3.6732 8.5893
BxPC-3 GDSC1; CTRP2 3.8511 5.5977 3.5581 8.4524
PK-59 CTRP2 3.9141 6.3785 3.2993 9.8554
QGP-1 GDSC1; CTRP2; CTRP1 4.1065 5.1005 4.0079 6.2675
KP-3 GDSC1; CTRP2; CTRP1 4.2928 7.4122 3.1956 8.8497
Capan-2 GDSC1; CTRP2; CTRP1 4.2974 6.2048 3.7719 6.6359
AsPC-1 GDSC1; CTRP2 4.3224 9.0277 1.5357 7.9879
SNU-410 CTRP2 4.3674 8.5282 2.7105 13.9786
SU.86.86 GDSC1; CTRP2 4.4704 7.8524 3.1373 8.6226
Panc 03.27 GDSC1; CTRP2; CTRP1 4.5618 7.297 3.5027 6.9646
Panc 08.13 GDSC1; CTRP2 4.5847 8.551 2.8946 9.3401
HPAF-II GDSC1; CTRP2 4.6327 8.8411 2.7929 9.6434
Panc 10.05 GDSC1; CTRP2 4.7773 6.3946 4.1355 4.0962
CFPAC-1 GDSC1; CTRP2 4.8153 13.9262 0.4112 18.1078
PaTu 8988t GDSC1; CTRP2 4.9231 6.0983 3.3032 0.3464
Panc 02.03 GDSC1; CTRP2 4.9728 11.2329 0.9348 9.36
PaTu 8902 GDSC1; CTRP2; CTRP1 5.0395 10.8303 2.157 11.4227
PK-45H CTRP2 5.0695 11.668 0.792 9.7735
TCC-Pan2 CTRP2 5.1409 6.9278 4.1819 3.4433
SUIT-2 GDSC1; CTRP2; CTRP1 5.2243 6.3178 4.5614 1.6793
YAPC GDSC1; CTRP2 5.2734 8.3962 3.5554 5.4663
Panc 05.04 CTRP2 5.4011 8.8216 3.4442 6.0679
Hs 766T GDSC1; CTRP2 7.541 9.2043 4.5058 0.1716
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 75 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 6.2446 27.1831 -5.9939 26.8056
WM1552C GDSC1 -0.2258 2.7037 -3.9727 2.0033
CP66-MEL GDSC1 -0.0373 1.8046 -3.5595 0.3138
451Lu GDSC1 0.058 2.0038 -3.5941 0.3582
GAK GDSC1 0.0975 1.4955 -3.4094 0.0643
MZ-MEL-2 GDSC1 0.1796 3.2292 -3.998 1.7062
M14 GDSC1 0.2373 2.7921 -3.8082 0.8957
CHL-1 GDSC1 0.2483 2.1879 -3.5892 0.2856
A-431 GDSC1 0.253 3.0124 -3.8838 1.1635
VMRC-MELG GDSC1 0.3071 2.3416 -3.621 0.3327
LB2518-MEL GDSC1 0.309 1.8786 -3.4646 0.0907
SH-4 GDSC1 0.3155 2.4175 -3.6443 0.3811
DJM-1 GDSC1 0.3315 2.6859 -3.7329 0.6032
MMAc-SF GDSC1 0.3771 1.9763 -3.474 0.0917
WM278 GDSC1 0.4254 2.5472 -3.6494 0.3549
COLO 783 GDSC1 0.436 2.1289 -3.5045 0.1157
HMV-II GDSC1 0.4522 3.4343 -3.9601 1.3111
WM35 GDSC1 0.469 7.6374 -5.7519 10.9998
Hs 938.T GDSC1 0.4728 2.4046 -3.584 0.2178
COLO 679 GDSC1 0.5772 2.8443 -3.6975 0.4095
A-388 GDSC1 0.6409 3.2662 -3.8228 0.7118
MZ-MEL-7 GDSC1 0.6586 2.7201 -3.6259 0.2437
CP50-MEL-B GDSC1 0.7687 3.0145 -3.6874 0.3265
SK-MEL-24 GDSC1 0.8684 2.6846 -3.5427 0.0994
LB373-MEL-D GDSC1 0.8693 2.7011 -3.5478 0.1042
G-mel GDSC1 0.9136 3.0284 -3.6414 0.2118
IST-MEL1 GDSC1 1.1087 3.1449 -3.6138 0.1418
WM266-4 CTRP2 2.0757 3.7449 1.915 11.4316
WM115 GDSC1; CTRP2 2.4398 5.0961 1.7948 10.8722
WM88 CTRP2 2.6336 3.8546 2.4907 7.6432
LOX-IMVI GDSC1; CTRP2 2.8898 4.7494 2.7664 13.6136
HT-144 GDSC1; CTRP2 2.9411 5.9049 1.9154 9.1447
MeWo GDSC1; CTRP2 2.9467 4.3118 2.6569 6.122
Malme-3M CTRP2 3.0226 6.0457 2.5019 15.3664
CJM [Human melanoma] CTRP2 3.0966 3.8996 2.9781 4.4668
WM983B CTRP2 3.1175 4.7718 2.6255 5.8078
UACC-62 GDSC1; CTRP2 3.1338 5.4486 2.3186 7.0303
Hs 294T CTRP2 3.1418 4.8639 2.6062 5.8273
COLO 800 GDSC1; CTRP2 3.2253 5.5851 2.3378 6.7415
COLO 829 GDSC1; CTRP2 3.2888 4.7226 2.8158 4.6153
SK-MEL-2 GDSC1; CTRP2 3.376 4.1873 3.1527 3.0276
RVH-421 GDSC1; CTRP2 3.402 6.5468 2.0215 7.6842
WT2-iPS GDSC1; CTRP2 3.4149 4.694 2.9495 3.7691
Hs 895.T CTRP2 3.4649 7.8563 1.4231 10.0674
IGR-1 GDSC1; CTRP2 3.6001 11.8981 -0.4822 17.3543
SK-MEL-3 GDSC1; CTRP2 3.8402 5.6318 2.8486 3.3325
COLO 792 GDSC1; CTRP2 3.9088 7.7378 1.8526 7.4007
WM1799 CTRP2 3.9494 7.0998 3.0052 10.9482
G-361 GDSC1; CTRP2; CTRP1 4.0407 5.434 3.8267 7.0775
UACC-257 GDSC1; CTRP2 4.0948 6.992 2.3707 4.8919
MDA-MB-435S CTRP2 4.1702 5.8755 3.7823 7.276
WM793 GDSC1; CTRP2 4.262 6.4181 3.6317 7.1662
Mel Ho GDSC1; CTRP2 4.3298 8.4017 2.7385 10.4655
Mel JuSo GDSC1; CTRP2 4.3547 5.0516 4.2897 4.521
Hs 852.T CTRP2; CTRP1 4.4058 5.5639 4.1649 5.239
A-375 GDSC1; CTRP2; CTRP1 4.4362 6.4111 3.8131 6.1605
SK-MEL-5 GDSC1; CTRP2; CTRP1 4.6037 5.6477 4.3331 3.8037
IGR-39 CTRP2 4.7693 8.4357 2.1535 4.7232
RPMI-7951 GDSC1; CTRP2 4.8819 6.2861 4.2834 3.3064
HMCB CTRP2 4.9053 8.9303 2.0088 5.1117
Hs 944.T CTRP2; CTRP1 4.916 6.0409 4.4443 3.5916
IPC-298 GDSC1; CTRP2 4.9616 6.369 4.3119 3.0399
Hs 688(A).T CTRP2 5.0653 10.1487 2.5097 10.5907
A101D GDSC1; CTRP2 5.1334 8.827 2.2104 3.992
SK-MEL-30 GDSC1; CTRP2 5.1441 7.5115 3.8929 4.3605
SK-MEL-1 GDSC1; CTRP2; CTRP1 5.1927 6.4344 4.4792 2.0514
IGR-37 GDSC1; CTRP2 5.1931 8.0416 3.6679 5.1613
Hs 936.T CTRP2; CTRP1 5.2197 6.6065 4.4147 2.4104
A2058 GDSC1; CTRP2 5.4596 6.4747 3.3751 0.0678
Hs 940.T GDSC1; CTRP2 5.4732 7.4566 4.1743 2.7266
SK-MEL-31 CTRP2 5.5181 8.5558 3.6662 4.9406
K029AX CTRP2 5.5661 10.0567 1.91 4.6089
Hs 839.T CTRP2 8.1837 25.4872 -3.7205 19.3354
SK-MEL-28 GDSC1; CTRP2; CTRP1 8.5839 16.2468 2.0584 6.6752
EquiPSC Line K2 GDSC1 0.7842 3.6372 -3.9015 0.8776
⏷ Show the Full List of 75 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-51 GDSC1 0.1877 3.0556 -3.9275 1.392
KYAE-1 GDSC1 0.3042 5.2431 -4.772 5.7094
SK-GT-4 GDSC1 0.4373 3.6132 -4.0347 1.6322
HCE-4 GDSC1 0.4467 2.424 -3.5997 0.2508
KYSE-50 GDSC1 0.5862 2.8354 -3.6911 0.3919
ESO-26 GDSC1 0.6557 3.1833 -3.7876 0.6038
KYSE-220 GDSC1 0.6585 3.0037 -3.7233 0.4396
TE-12 GDSC1 0.7351 3.3185 -3.8057 0.6174
FLO-1 GDSC1 0.8359 4.7867 -4.3175 2.5299
OACM5.1 C GDSC1 0.8811 8.7408 -6.0087 11.5243
OACP4 C GDSC1 0.9 3.1075 -3.6728 0.2649
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 3.5449 4.7839 3.0242 3.1697
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LA-N-6 GDSC1 -0.6846 2.3469 -4.0482 3.0104
SJNB-6 GDSC1 -0.3845 4.7973 -4.9654 8.1806
GI-ME-N GDSC1 -0.2416 7.3004 -6.0447 14.1614
SJNB-17 GDSC1 -0.0681 3.0413 -4.0352 2.1389
SJNB-13 GDSC1 0.0143 2.236 -3.6928 0.6463
SJNB-12 GDSC1 0.0241 3.2023 -4.0571 2.1456
SJNB-7 GDSC1 0.1164 2.756 -3.8438 1.1108
SK-N-AS GDSC1 0.1441 2.3391 -3.6802 0.5431
NH-12 GDSC1 0.1636 2.1772 -3.616 0.3706
SK-N-BE(2)-M17 GDSC1 0.1923 2.2978 -3.6476 0.4356
SJNB-14 GDSC1 0.2007 2.0135 -3.5465 0.2197
IMR-5 GDSC1 0.2379 2.4147 -3.6718 0.4786
SiMa GDSC1 0.2656 3.1208 -3.9195 1.2951
SJNB-5 GDSC1 0.3368 2.1251 -3.5369 0.1743
NB(TU)1 GDSC1 0.4407 2.541 -3.6418 0.3338
CHP-134 GDSC1 0.4466 2.3294 -3.5677 0.1978
SK-N-MC-IXC GDSC1 0.4687 2.0424 -3.4652 0.0737
KP-N-YS GDSC1 0.4727 6.7996 -5.3679 8.8544
TGW GDSC1 0.4845 2.14 -3.4919 0.0962
GOTO GDSC1 0.4929 2.9465 -3.7647 0.6162
SK-N-FI GDSC1 0.6099 2.6552 -3.6209 0.2471
SJNB-10 GDSC1 0.6406 2.6004 -3.5918 0.1938
NB69 GDSC1 0.7006 3.8534 -4.015 1.3365
CHP-212 GDSC1 0.7647 2.3651 -3.4728 0.0542
KP-N-YN GDSC1; CTRP2 1.3401 4.8565 0.7371 17.9866
MHH-NB-11 GDSC1; CTRP2 2.3535 11.1685 -0.4726 26.2664
SK-N-SH GDSC1; CTRP2 2.4707 5.7969 1.509 11.9415
NH-6 CTRP2 2.549 4.8002 2.0359 9.6289
SK-N-DZ GDSC1; CTRP2 3.2139 8.9401 0.6649 13.7162
KP-N-SI9s CTRP2 3.4963 6.2109 2.938 12.3818
Kelly GDSC1; CTRP2 3.9692 4.7867 3.93 6.8413
CHP-126 GDSC1; CTRP2 3.9951 6.2606 3.4342 8.5412
SK-N-BE(2) CTRP2 4.0509 5.9442 3.6292 8.1937
NB1 GDSC1; CTRP2 4.1222 5.0091 4.0474 6.0046
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-28 CTRP2 2.4766 5.145 2.2139 18.0289
SNU-869 CTRP2 3.6337 29.6208 -9.3154 35.2741
SNU-478 CTRP2 3.6598 5.6385 3.3378 10.3925
SNU-1196 CTRP2 4.0559 6.5846 3.3496 9.2937
SNU-308 CTRP2 4.51 6.0409 4.0523 5.3312
HuCC-T1 GDSC1; CTRP2 5.3019 7.5843 3.9822 3.7427
SNU-245 CTRP2 5.9396 8.8098 3.8454 3.5516
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-157 GDSC1; CTRP2 -0.2269 5.6452 -0.8829 34.8012
OCUB-M GDSC1 0.006 2.1568 -3.6675 0.5739
HCC2157 GDSC1 0.0414 9.2907 -6.8052 17.2491
MFM-223 GDSC1 0.0675 1.9016 -3.5553 0.272
HCC1187 GDSC1 0.1022 2.5912 -3.7881 0.9128
HCC1569 GDSC1 0.1066 3.4923 -4.1353 2.4441
MDA-MB-436 GDSC1 0.1911 2.387 -3.6795 0.5195
MRK-nu-1 GDSC1 0.2493 1.7728 -3.4498 0.0836
BT-483 GDSC1 0.2873 2.5712 -3.7088 0.556
HCC1599 GDSC1 0.4449 2.2472 -3.5408 0.1591
HCC2218 GDSC1 0.4559 3.3985 -3.9451 1.2493
COLO 824 GDSC1 0.5201 3.1949 -3.8438 0.8433
UACC-812 GDSC1 0.589 5.36 -4.6724 4.6927
MDA-MB-175-VII GDSC1 0.5942 2.5186 -3.5804 0.1863
Evsa-T GDSC1 0.6127 2.5448 -3.5828 0.1862
UACC-893 GDSC1 0.672 3.072 -3.7423 0.4796
HCC70 GDSC1 0.7255 2.8417 -3.6437 0.2578
YMB-1-E GDSC1 0.765 3.4539 -3.8427 0.7077
EFM-19 GDSC1 0.836 3.1455 -3.7084 0.3481
MDA-MB-330 GDSC1 0.9631 3.2046 -3.6837 0.2681
DU4475 GDSC1; CTRP2 2.4953 3.8658 2.3366 8.6241
HCC1419 GDSC1; CTRP2 2.5683 11.8747 -1.3647 22.6086
Hs 578T GDSC1; CTRP2 2.5824 6.7516 1.166 13.0687
CAL-85-1 GDSC1; CTRP2 2.6215 4.8781 2.0769 9.2756
ZR-75-30 GDSC1; CTRP2 2.9237 5.278 2.1979 8.0249
EFM-192A GDSC1; CTRP2 3.085 5.3076 2.3401 7.0556
HCC1500 GDSC1; CTRP2 3.2445 8.4407 0.9404 12.5267
MDA-MB-468 GDSC1; CTRP2 3.4233 5.625 2.4984 5.6359
MDA-MB-453 GDSC1; CTRP2 3.5111 6.1644 2.9727 11.4444
BT-20 GDSC1; CTRP2 3.517 5.459 2.6639 4.7426
HCC38 GDSC1; CTRP2 3.5783 5.282 2.8057 4.019
HCC1395 GDSC1; CTRP2 3.7274 6.4801 3.0633 10.5717
CAL-51 GDSC1; CTRP2 3.8171 6.1883 3.2823 9.5405
MDA-MB-231 GDSC1; CTRP2 3.84 6.0931 3.3466 9.2469
HCC1143 CTRP2 3.8508 6.5205 3.1717 10.526
HMC-1-8 CTRP2 3.9423 5.3901 3.7322 8.0975
HCC1428 GDSC1; CTRP2 3.9479 5.716 2.8907 2.9664
CAL-120 GDSC1; CTRP2 4.5676 6.8828 3.7029 6.2179
BT-549 GDSC1; CTRP2 4.5739 6.4811 2.9531 1.8088
MCF-7 GDSC1; CTRP2; CTRP1 4.6047 6.6753 3.8467 5.6625
HCC202 CTRP2 4.6494 8.9539 1.8165 6.285
HCC1954 GDSC1; CTRP2 4.6794 6.2215 4.1295 4.3251
HCC1937 GDSC1; CTRP2 4.8146 7.096 3.8213 5.2526
AU565 GDSC1; CTRP2 4.8323 8.6153 3.0792 8.1357
CAMA-1 GDSC1; CTRP2 4.8362 7.4729 2.9709 3.4203
HDQ-P1 GDSC1; CTRP2 4.8431 6.8309 3.9783 4.5801
CAL-148 GDSC1; CTRP2 4.9744 5.9876 4.5132 2.2235
MDA-MB-361 GDSC1; CTRP2 5.0646 6.2739 4.4464 2.3203
MDA-MB-415 GDSC1; CTRP2 5.1206 9.3941 2.9327 8.1819
HCC1806 GDSC1; CTRP2 5.2141 15.3651 0.0247 18.6199
T-47D GDSC1; CTRP2 5.5823 10.1448 2.9275 7.414
ZR-75-1 CTRP2 5.6363 8.211 3.9232 3.6857
Hs 578Bst CTRP2 5.8939 10.5474 2.9648 7.2243
KPL-1 CTRP2 5.9921 6.8309 4.7642 0.204
JIMT-1 GDSC1; CTRP2 6.23 10.9873 2.9937 6.167
BT-474 GDSC1; CTRP2 7.0869 8.541 4.5707 0.1846
SK-BR-3 CTRP2 7.2366 11.3525 3.4758 3.3714
BT 440 CTRP2 1.9128 4.9416 1.6543 21.7627
BT 112 CTRP2 2.4531 4.8468 1.9165 10.3549
BT 145 CTRP2 2.5872 4.7386 2.1019 9.2672
BT164 CTRP2 2.8717 4.5755 2.4662 7.0738
BT 179 CTRP2 3.3399 4.6832 2.8837 4.2151
BT 416 CTRP2 4.0377 5.4725 3.805 7.5507
BT 172 CTRP2 4.1577 6.4184 3.5276 8.3228
BT 286 CTRP2 4.2065 6.453 3.5603 8.0691
BT 504 CTRP2 4.2625 5.8358 3.8948 6.5893
BT 330 CTRP2 4.3019 5.735 3.9789 6.1544
BT147 CTRP2 4.3187 7.1222 3.3525 8.6485
BT 271 CTRP2 4.3413 6.9952 3.4352 8.2558
BT 248 CTRP2 4.4184 7.6285 3.1997 9.0527
BT 482 CTRP2 4.472 6.0885 3.9926 5.666
BT 245 CTRP2 4.5217 5.947 4.1075 5.0785
BT 224 CTRP2 4.7798 8.0538 2.3443 3.9376
BT 131 CTRP2 4.791 6.8964 3.8996 5.3247
BT 428 CTRP2 4.865 7.9601 3.4344 7.1215
BT 232 CTRP2 4.9577 7.4566 3.7653 5.5463
BT 231 CTRP2 5.1533 14.4884 0.4128 18.4642
BT 359 CTRP2 5.2016 6.3566 4.5143 1.9427
BT 333 CTRP2 5.212 6.6094 4.3968 2.4153
BT 320 CTRP2 5.4944 7.2837 4.274 2.466
BT 422 CTRP2 5.5119 8.0766 3.8981 3.9879
BT 216 CTRP2 5.5755 7.6871 4.1352 2.9101
BT 239 CTRP2 5.6013 9.6437 3.1908 6.7779
BT 328 CTRP2 5.6571 7.5153 4.2747 2.2261
BT 340 CTRP2 5.7997 7.588 4.3334 1.8065
BT 228 CTRP2 6.1073 13.2134 1.8083 11.5347
BT 498 CTRP2 6.5565 10.7801 3.3177 4.8035
BT 444 CTRP2 6.7382 7.85 4.6849 0.1165
BT 159 CTRP2 6.8456 10.8341 3.4775 3.8124
BT 187 CTRP2 9.0358 20.6989 0.2416 12.6865
BT 139 CTRP2 10.384 20.1877 1.3238 7.5397
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 3.9276 6.9989 3.0307 10.8986
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-247MG GDSC1 -3.6557 6.4324 -8.2515 33.6244
LN-405 GDSC1 -0.2682 2.6205 -3.9589 1.9818
M059J GDSC1 -0.2509 1.9269 -3.6843 0.7757
H4 GDSC1 -0.1294 3.1884 -4.1237 2.6702
SK-MG-1 GDSC1 0.0532 3.2391 -4.0585 2.1203
D-336MG GDSC1 0.0806 3.9176 -4.3225 3.4763
MOG-G-UVW GDSC1 0.1646 2.3483 -3.6757 0.5212
KINGS-1 GDSC1 0.1727 2.9563 -3.896 1.2743
D-502MG GDSC1 0.177 2.6953 -3.7966 0.8937
D-263MG GDSC1 0.1951 1.8246 -3.485 0.1297
AM-38 GDSC1 0.2256 4.3879 -4.4469 3.9652
D-566MG GDSC1 0.2513 3.2012 -3.9562 1.4586
MOG-G-CCM GDSC1 0.302 2.7428 -3.7647 0.7135
D-542MG GDSC1 0.3867 2.1874 -3.5406 0.1699
YKG-1 GDSC1 0.4066 2.1589 -3.5243 0.1442
PFSK-1 GDSC1 0.4187 2.9059 -3.7785 0.6937
D-392MG GDSC1 0.4266 6.6193 -5.3134 8.6325
Onda 10 GDSC1 0.5163 3.3696 -3.9096 1.0725
GI-1 GDSC1 0.5752 2.5798 -3.6075 0.2328
KNS-42 GDSC1 0.6097 2.2925 -3.5002 0.0894
LNZTA3WT4 GDSC1 0.6275 2.5895 -3.5927 0.1978
KNS-81-FD GDSC1 0.7782 5.1902 -4.5075 3.5439
KS-1 [Human Krukenberg tumour] GDSC1 0.9447 3.801 -3.8986 0.7816
Onda 11 GDSC1 0.9691 3.37 -3.738 0.3675
D-423MG GDSC1 1.0824 4.5018 -4.1012 1.3836
SF539 GDSC1; CTRP2 1.3176 3.4835 1.2737 23.4162
A-172 GDSC1; CTRP2 2.1446 5.699 1.2261 13.9041
T98G GDSC1; CTRP2 2.3036 6.4961 1.0178 14.342
D283 Med GDSC1; CTRP2 2.6006 4.0636 2.3846 8.1362
Hs 683 GDSC1; CTRP2 2.8617 7.6605 0.9843 13.1738
DK-MG GDSC1; CTRP2 2.9449 11.8202 -1.0051 20.5772
SW1783 GDSC1; CTRP2 2.9878 4.8786 2.4475 6.8518
SF268 GDSC1; CTRP2 2.9959 6.623 2.2426 15.4112
SNU-1105 CTRP2 3.0585 5.4683 2.4245 9.899
SF126 GDSC1; CTRP2 3.1481 5.5189 2.8283 12.9167
LN-18 GDSC1; CTRP2 3.2892 4.615 3.2267 11.1631
SNU-466 CTRP2 3.301 4.3636 3.2753 11.7015
SNB-75 GDSC1; CTRP2 3.3672 8.5161 1.7693 16.2686
GaMG GDSC1; CTRP2; CTRP1 3.4543 5.141 3.2846 10.5718
SNU-738 CTRP2 3.5446 5.9531 3.0935 11.6478
U-118MG GDSC1; CTRP2 3.7711 7.3098 1.9543 7.2314
KNS-60 CTRP2 3.8009 6.3405 3.1999 10.5434
CCF-STTG1 CTRP2 3.9539 13.1839 -0.8317 17.8957
SW1088 GDSC1; CTRP2 4.0119 7.1238 3.0554 9.9309
LN-229 GDSC1; CTRP2; CTRP1 4.0724 5.4694 3.8477 6.9186
CAS-1 GDSC1; CTRP2 4.0994 5.4033 3.8968 6.5888
42-MG-BA GDSC1; CTRP2 4.1312 16.1924 -1.3078 24.6116
GB-1 GDSC1; CTRP2 4.1632 8.1721 2.6968 10.9771
SNU-489 CTRP2 4.3236 6.1812 3.8023 6.8019
ONS-76 GDSC1; CTRP2 4.4163 6.1986 3.8863 5.8442
M059K CTRP2 4.4169 8.7162 1.7617 6.8886
KG-1-C CTRP2 4.7858 8.5553 3.069 8.8142
YH-13 GDSC1; CTRP2 4.8456 12.666 0.1326 12.7195
U-87MG ATCC GDSC1; CTRP2 4.9089 7.1728 3.1639 2.5459
Daoy GDSC1; CTRP2 4.9201 8.2264 3.3486 6.9107
Becker GDSC1; CTRP2 4.9384 9.1465 1.9273 5.3936
KNS-81 CTRP2 5.0195 9.1897 2.951 8.8425
SF295 GDSC1; CTRP2; CTRP1 5.0278 6.8794 4.1226 3.743
GMS-10 CTRP2 5.2157 8.166 2.5684 2.517
KALS-1 GDSC1; CTRP2 5.3377 7.5285 4.0375 3.468
DBTRG-05MG GDSC1; CTRP2 5.3625 9.604 3.0239 7.4026
TM-31 CTRP2 5.3976 9.1857 2.2101 3.6599
U-251MG GDSC1; CTRP2 5.4771 7.633 4.0907 3.0442
GOS-3 CTRP2 5.4969 9.3106 2.2136 3.5275
NMC-G1 GDSC1; CTRP2 5.5341 7.6166 4.14 2.7694
SNU-201 CTRP2 5.6013 17.3164 -0.6339 20.948
8-MG-BA GDSC1; CTRP2 5.8552 11.1632 1.5756 5.5361
SNU-626 CTRP2 5.8803 9.8027 3.3208 5.7804
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1 0.6254 2.6006 -3.5971 0.205
ETK-1 GDSC1 0.6845 3.2804 -3.8113 0.6566
TGBC24TKB GDSC1 0.8662 3.0149 -3.6533 0.2405
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-280 GDSC1 -0.0947 4.1287 -4.5027 4.7833
AN3-CA GDSC1; CTRP2 0.0426 4.0431 -0.39 25.9707
JHUEM-2 CTRP2; CTRP1 1.2844 3.8206 1.1999 25.4077
JHUEM-7 CTRP2 2.0584 4.2607 1.7293 12.1722
JHUEM-1 CTRP2 2.3347 25.4275 -8.3212 36.386
MFE-296 GDSC1; CTRP2 2.7046 7.3262 1.6417 18.3292
JHUEM-3 CTRP2 2.9841 4.7894 2.4847 6.7108
ESS-1 GDSC1; CTRP2 3.1915 4.8407 2.6656 5.4643
RL95-2 GDSC1; CTRP2 3.8184 5.0591 3.3626 3.5991
HEC-151 CTRP2; CTRP1 4.204 5.4982 3.9777 6.5147
HEC-1-A CTRP2 4.2059 6.6386 3.4735 8.4221
HEC-1-B CTRP2 4.3433 6.0342 3.3182 2.9608
KLE GDSC1; CTRP2; CTRP1 4.4139 5.8848 4.0342 5.3753
HEC-108 CTRP2; CTRP1 4.4574 5.9428 4.0519 5.552
MFE-319 GDSC1; CTRP2; CTRP1 4.5735 6.5951 3.8564 5.5919
HEC-50B CTRP2 4.6084 11.5274 1.4328 19.4209
HEC-265 CTRP2; CTRP1 4.6333 6.2396 4.0849 4.9918
HEC-6 CTRP2; CTRP1 4.7605 6.1665 4.2402 4.0599
HEC-59 CTRP2; CTRP1 4.8201 7.5947 3.5868 6.658
EN GDSC1; CTRP2 5.013 8.2697 2.3951 3.4233
EFE-184 CTRP2 5.5587 7.9011 4.0187 3.4144
HEC-251 CTRP2; CTRP1 5.589 8.2875 3.8622 4.0906
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 5.1372 6.7915 4.2569 3.2198
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BB65-RCC GDSC1 0.1437 2.5656 -3.7621 0.7962
BFTC-909 GDSC1 0.2267 2.2303 -3.6115 0.3387
NCC021 GDSC1 0.2387 2.3383 -3.6447 0.4104
SW156 GDSC1 0.2692 2.5474 -3.7071 0.5598
LB996-RCC GDSC1 0.3778 2.8227 -3.7643 0.6721
KTCTL-13 GDSC1 0.3824 2.7436 -3.7342 0.5826
KTCTL-26A GDSC1 0.3912 2.6598 -3.7012 0.4901
KTCTL-21 GDSC1 0.4043 3.7607 -4.1065 1.9835
CAL-54 GDSC1 0.4758 2.4696 -3.605 0.2528
RXF 393L GDSC1 0.5791 3.0323 -3.7627 0.5709
TK-10 GDSC1 0.5846 3.0914 -3.7817 0.6205
SW13 GDSC1 0.5929 2.4558 -3.5598 0.1581
KTCTL-195 GDSC1 0.635 2.3796 -3.5204 0.1059
LB1047-RCC GDSC1 0.6498 3.7354 -3.9917 1.2844
SN12C GDSC1 0.7671 2.6153 -3.5538 0.1235
KTCTL-140 GDSC1 0.7939 3.1286 -3.7176 0.3803
HA7-RCC GDSC1 0.7957 3.0213 -3.6802 0.305
KTCTL-1M GDSC1 0.8903 3.4192 -3.7836 0.4955
A-704 GDSC1 0.9807 3.0678 -3.6316 0.1848
UO-31 GDSC1; CTRP2 1.0044 7.774 -0.3238 29.4344
LB2241-RCC GDSC1 1.0282 2.8648 -3.5487 0.0875
TUHR14TKB CTRP2 1.2945 7.0517 0.2707 28.4877
A-498 GDSC1; CTRP2 1.515 2.6321 1.5014 14.6615
KMRC-2 CTRP2 2.0212 3.6011 1.894 11.6743
786-O GDSC1; CTRP2 3.3447 6.3277 2.0797 7.5607
VMRC-RCZ GDSC1; CTRP2 3.716 5.2848 2.9212 3.2579
KMRC-1 GDSC1; CTRP2 3.8496 6.4767 2.4346 5.0593
VMRC-RCW GDSC1; CTRP2; CTRP1 3.8848 5.2837 3.7098 7.9104
OS-RC-2 GDSC1; CTRP2 3.9341 8.4123 1.7959 9.8949
Caki-1 GDSC1; CTRP2 4.1355 8.9318 1.4379 8.7238
KMRC-20 GDSC1; CTRP2 4.2426 7.2987 3.195 8.8815
TUHR10TKB CTRP2 4.4493 5.0557 4.3918 5.2147
769-P GDSC1; CTRP2 4.5887 13.3953 0.4833 18.305
RCC10RGB GDSC1; CTRP2; CTRP1 4.7576 6.6728 3.9889 4.791
ACHN GDSC1; CTRP2 4.9233 8.5281 2.214 4.2604
Caki-2 CTRP2 4.9878 8.8385 2.1089 4.5915
SNU-1272 CTRP2 5.2489 7.265 4.0996 3.5936
TUHR4TKB CTRP2 5.5559 8.8277 3.5603 5.3177
KMRC-3 CTRP2 7.4825 10.4616 3.9967 1.3841
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 61 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H716 GDSC1; CTRP2 -1.7672 2.2052 -1.9349 37.0769
SW626 GDSC1 0.1352 3.1704 -3.9946 1.7332
SW1463 GDSC1 0.1685 2.0899 -3.584 0.2993
CaR-1 GDSC1 0.3474 3.0349 -3.8537 0.9846
HCC2998 GDSC1 0.3534 2.5177 -3.6653 0.4163
GP5d GDSC1 0.3953 2.0715 -3.4992 0.1157
COLO 320HSR GDSC1 0.642 3.1003 -3.7633 0.545
SW837 GDSC1 0.7645 2.6364 -3.5616 0.1327
SNU-C2B GDSC1 0.9704 3.8396 -3.9026 0.7803
KM12 GDSC1; CTRP2; CTRP1 1.1001 8.2833 -0.4279 29.5214
GP2d CTRP2 2.1971 4.0702 1.9457 10.9565
SW48 GDSC1; CTRP2 2.2403 3.8404 2.2099 17.6103
SNU-C1 GDSC1; CTRP2 2.7307 4.4215 2.3849 7.7705
SW1417 GDSC1; CTRP2 2.8177 4.8937 2.2699 7.9973
C2BBe1 GDSC1; CTRP2 3.1965 4.5992 2.784 4.9684
HCT 15 GDSC1; CTRP2 3.4133 4.2871 3.1434 2.9732
COLO201 CTRP2 3.4154 14.9091 -1.3036 27.4034
LS1034 GDSC1; CTRP2 3.4831 4.2557 3.2259 2.4674
COLO205 GDSC1; CTRP2 3.5892 11.1149 0.1503 17.1642
T84 GDSC1; CTRP2 3.6108 5.9821 3.1519 10.5386
SK-CO-1 CTRP2 3.6612 4.9255 3.5656 9.547
HCC-56 CTRP2 3.6729 4.3406 3.3571 1.5028
LoVo GDSC1; CTRP2; CTRP1 3.793 5.6796 3.4693 9.0041
NCI-H747 GDSC1; CTRP2 3.8498 5.7997 3.4779 8.7438
SNU-407 GDSC1; CTRP2 3.8845 5.0526 3.7764 7.5996
SW620 GDSC1; CTRP2; CTRP1 3.9014 5.1861 3.7588 7.6951
DLD-1 CTRP2 3.9162 5.1884 3.771 8.0299
SNU-1040 GDSC1; CTRP1 3.9937 5.1296 3.8764 7.0337
HCT 8 CTRP2; CTRP1 4.0068 5.357 3.8174 7.6811
SNU-503 CTRP2 4.0272 5.5024 3.0551 2.1514
SW1116 GDSC1; CTRP2 4.0561 6.5617 3.3604 8.6721
LS180 GDSC1; CTRP2; CTRP1 4.1349 5.7022 3.8234 6.8432
HT115 GDSC1; CTRP2; CTRP1 4.1749 5.1882 4.056 5.911
CCK-81 GDSC1; CTRP2 4.1817 5.3638 3.9998 6.0045
SW480 CTRP1 4.1831 6.1553 3.6788 16.599
RCM-1 [Human ESC] GDSC1; CTRP2; CTRP1 4.1958 6.0226 3.7506 6.8366
CL-11 GDSC1; CTRP2 4.219 5.7583 3.8829 6.3295
HT-55 GDSC1; CTRP2; CTRP1 4.2304 5.9657 3.8111 6.6499
SW948 GDSC1; CTRP2; CTRP1 4.2611 5.3563 4.0921 5.4527
COLO 320 CTRP2; CTRP1 4.2884 9.1432 2.3437 12.9568
LS513 GDSC1; CTRP2 4.3396 5.7077 4.0297 5.4892
RKO GDSC1; CTRP2; CTRP1 4.3888 6.253 3.8407 6.1633
SNU-C5 GDSC1; CTRP2; CTRP1 4.473 5.5475 4.2421 4.4606
CL-34 CTRP1 4.5173 6.2486 3.9689 12.3195
SNU-C2A CTRP2; CTRP1 4.5616 6.0124 4.1235 5.0053
HCT 116 GDSC1; CTRP2; CTRP1 4.5617 5.9429 4.1559 4.5695
SNU-C4 CTRP2; CTRP1 4.5783 5.4177 4.4063 3.8347
SNU-61 GDSC1; CTRP2; CTRP1 4.6712 6.098 4.1891 4.1964
SNU-175 GDSC1; CTRP1 4.7035 5.5353 4.4847 2.9976
COLO 678 GDSC1; CTRP2; CTRP1 4.7608 5.9891 4.3269 3.4095
SW403 CTRP1 4.7719 6.6721 4.0022 10.7772
NCI-H508 CTRP2; CTRP1 4.8393 6.2063 4.2933 3.6652
LS411N GDSC1; CTRP2 4.8641 6.0345 4.3921 2.9168
SNU-81 GDSC1; CTRP1 4.9667 5.9621 4.5283 2.2619
LS123 GDSC1; CTRP2; CTRP1 5.0152 8.5059 3.2989 7.0084
HT-29 GDSC1; CTRP2; CTRP1 5.1368 7.1938 4.0557 3.8113
MDST8 GDSC1; CTRP2; CTRP1 5.1531 6.3773 4.4765 2.1282
CL-40 CTRP1 5.2697 6.8001 4.3571 5.5043
CW-2 GDSC1; CTRP2; CTRP1 5.5834 7.1077 4.4317 1.6666
OUMS-23 CTRP2 5.8564 9.6964 3.3555 5.6755
SNU-1033 CTRP2 7.6444 9.7758 4.3393 0.4284
⏷ Show the Full List of 61 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 0.624 5.7653 -4.8273 5.5055
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep-G2/C3A GDSC1 0.1603 1.9086 -3.5251 0.1937
JHH-7 GDSC1 0.4036 3.5443 -4.0227 1.6101
HLE GDSC1 0.5158 2.8387 -3.718 0.4816
Huh-7 GDSC1 0.7663 2.7883 -3.6116 0.1976
Li-7 CTRP2 1.2714 5.4724 0.8024 26.7583
JHH-4 GDSC1; CTRP2 1.9525 6.2047 0.8037 16.0792
Hep 3B2.1-7 GDSC1; CTRP2 2.5001 4.5555 2.208 11.5908
SNU-878 CTRP2 2.5875 4.8944 2.4026 17.0112
JHH-5 CTRP2 2.6858 4.1641 2.4392 7.6855
JHH-2 GDSC1; CTRP2 2.8582 5.6824 1.9427 9.2277
SNU-423 GDSC1; CTRP2 2.9937 4.3741 2.6793 5.9081
SNU-449 GDSC1; CTRP2; CTRP1 3.1758 4.8482 3.0573 11.922
PLC/PRF/5 CTRP2 3.1904 4.7586 2.7033 5.3124
JHH-1 GDSC1; CTRP2 3.3016 4.3921 2.9842 3.8956
SNU-475 GDSC1; CTRP2 3.4114 6.6473 1.9797 7.8405
HuH-6 CTRP2 3.5503 5.9873 3.0859 11.6613
SNU-182 CTRP2 3.584 6.0882 3.0806 11.5897
HLF CTRP2 3.6377 7.2852 1.8555 7.9058
SNU-761 CTRP2 3.6759 5.2791 3.4808 9.8104
SNU-387 GDSC1; CTRP2 3.8201 6.4588 2.4197 5.1769
HuH-1 GDSC1; CTRP2 3.9753 7.0743 2.2367 5.6637
Hep-G2 CTRP2; CTRP1 4.2566 6.1299 3.7648 7.2094
JHH-6 GDSC1; CTRP2; CTRP1 4.6161 5.1055 4.5621 2.8901
SNU-398 GDSC1; CTRP2; CTRP1 4.9538 7.0795 3.9597 4.5215
SK-HEP-1 GDSC1; CTRP2 5.776 9.8118 2.1523 3.4375
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 217 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1703 GDSC1; CTRP2 -3.5578 9.7147 -6.4023 49.1976
EMC-BAC-1 GDSC1 -0.4745 4.4718 -4.8706 7.7738
NCI-H2818 GDSC1 -0.463 2.9312 -4.1823 3.4646
DV-90 CTRP2 -0.1401 3.9693 -0.5672 27.1618
NCI-H1341 CTRP2 -0.0962 3.4628 -0.3806 26.3729
NCI-H209 GDSC1 -0.0915 6.0905 -5.3817 10.085
Lu-134-A GDSC1 -0.0913 4.7271 -4.7632 6.3517
NCI-H748 GDSC1 -0.0572 6.8144 -5.6966 11.8241
NCI-H345 GDSC1 -0.043 0.8739 -3.2553 0.0047
Lu-135 GDSC1 -0.0421 4.3015 -4.5493 4.9745
NCI-H720 GDSC1 -0.0357 1.3606 -3.4094 0.0786
LC-2/ad GDSC1 -0.0301 5.1941 -4.9367 7.292
NCI-H2373 GDSC1 -0.005 3.056 -4.0122 1.9576
NCI-H2369 GDSC1 -0.0043 1.7874 -3.5417 0.2663
SBC-3 GDSC1 -0.0015 2.9716 -3.9774 1.7882
CPC-N GDSC1 0.0017 2.1073 -3.6514 0.5294
NCI-H1436 GDSC1 0.0193 2.4708 -3.7769 0.9282
NCI-H64 GDSC1 0.0596 1.4604 -3.4104 0.0689
NCI-H2731 GDSC1 0.0818 2.9439 -3.93 1.4946
NCI-H1304 GDSC1 0.1045 1.957 -3.5611 0.2726
NCI-H290 GDSC1 0.1322 6.1776 -5.2864 9.0575
NCI-H1770 GDSC1 0.1368 1.9614 -3.5512 0.2446
NCI-H2869 GDSC1 0.1574 3.0183 -3.9261 1.412
IA-LM GDSC1 0.1579 2.0512 -3.5745 0.2832
UMC-11 GDSC1 0.158 2.4993 -3.7324 0.6914
NCI-H2227 GDSC1 0.1752 2.8254 -3.8456 1.0743
NCI-H2171 GDSC1 0.186 1.7673 -3.4691 0.112
NCI-H510A GDSC1 0.1887 2.5822 -3.7505 0.7318
NCI-H3122 GDSC1 0.2338 3.0026 -3.888 1.1945
NCI-H847 GDSC1 0.2526 6.9787 -5.5806 10.5007
NCI-H524 GDSC1 0.3111 2.7416 -3.7608 0.6965
NCI-H1688 GDSC1 0.3153 3.3927 -4.0023 1.6005
NCI-H2803 GDSC1 0.3295 2.8583 -3.7959 0.7978
NCI-H2722 GDSC1 0.3466 2.2379 -3.5715 0.2269
Lu-139 GDSC1 0.3548 6.1196 -5.1305 7.713
Lu-99A GDSC1 0.3618 2.7746 -3.7531 0.647
COR-L303 GDSC1 0.3656 2.3996 -3.62 0.3123
NCI-H513 GDSC1 0.3739 3.1665 -3.8918 1.106
NCI-H1648 GDSC1 0.3899 2.8441 -3.7674 0.6751
NCI-H2591 GDSC1 0.4078 3.4719 -3.9931 1.4812
NCI-H2795 GDSC1 0.4107 3.0965 -3.8511 0.9343
DMS 79 GDSC1 0.4125 2.6811 -3.7008 0.4802
LC-1/sq GDSC1 0.4844 3.1069 -3.8258 0.8053
NCI-H2595 GDSC1 0.5028 2.7269 -3.6837 0.4044
COR-L311 GDSC1 0.5238 2.9138 -3.7415 0.5386
NCI-H1993 GDSC1 0.534 3.0984 -3.8035 0.709
Lu-165 GDSC1 0.579 6.9717 -5.3836 8.7401
NCI-H1693 GDSC1 0.5846 3.5443 -3.9469 1.1622
Ms-1 GDSC1 0.5956 2.5662 -3.5958 0.2094
EMC-BAC-2 GDSC1 0.5963 3.764 -4.0248 1.4563
NCI-H2135 GDSC1 0.6047 2.6911 -3.635 0.2731
IST-SL1 GDSC1 0.6105 2.8063 -3.6723 0.3438
LK-2 GDSC1 0.6223 3.3047 -3.8439 0.7858
RERF-LC-Sq1 GDSC1 0.6251 4.1921 -4.1776 2.0924
NCI-H2347 GDSC1 0.6297 2.8442 -3.6785 0.3506
ABC-1 GDSC1 0.6315 3.2475 -3.8197 0.7073
NCI-H187 GDSC1 0.6383 9.9669 -6.7318 15.561
SBC-1 GDSC1 0.6407 2.4103 -3.5286 0.1137
NCI-H322M GDSC1 0.6597 2.5398 -3.565 0.1534
NCI-H2804 GDSC1 0.6692 3.0133 -3.7228 0.4344
NCI-H2461 GDSC1 0.6817 2.6937 -3.609 0.2112
IST-SL2 GDSC1 0.6998 6.2969 -5.0169 6.4517
HCC33 GDSC1 0.7262 2.7612 -3.6163 0.213
COR-L321 GDSC1 0.7994 2.8711 -3.628 0.2153
A-427 GDSC1 0.8171 3.647 -3.8922 0.83
PaCa-3 GDSC1 0.8225 3.5793 -3.8657 0.7465
SW1573 GDSC1 0.8271 3.3513 -3.783 0.5188
PC-14 GDSC1; CTRP2 1.6033 4.5791 1.4051 22.134
NCI-H520 GDSC1; CTRP2 1.7371 6.7973 0.8408 23.2602
HCC827 GDSC1; CTRP2; CTRP1 1.8334 4.2788 1.717 20.5008
HOP-92 GDSC1; CTRP2 2.1709 4.7029 1.9947 18.5189
NCI-H1568 GDSC1; CTRP2; CTRP1 2.2061 5.3941 1.8479 18.6547
EKVX GDSC1; CTRP2 2.2463 5.1533 1.9603 18.4181
NCI-H358 GDSC1; CTRP2 2.2581 6.3678 1.562 19.7682
NCI-H2085 GDSC1; CTRP2 2.2921 5.618 1.8666 18.6112
RERF-LC-MS GDSC1; CTRP2 2.3744 4.4923 1.9801 10.3208
Lu-65 GDSC1; CTRP2 2.3904 4.7624 1.8869 10.6395
NCI-H1581 GDSC1; CTRP2 2.4371 7.5636 1.2627 20.363
NCI-H1975 GDSC1; CTRP2; CTRP1 2.4997 4.1977 2.4454 16.1427
NCI-H1048 GDSC1; CTRP1 2.6819 5.3205 2.3889 15.8029
NCI-H810 GDSC1; CTRP2; CTRP1 2.7791 4.8907 2.6147 14.5027
COR-L105 GDSC1; CTRP2 2.7807 4.9429 2.2103 8.3313
NCI-H647 GDSC1; CTRP2 2.8161 4.1882 2.5691 6.8212
NCI-H1734 GDSC1; CTRP2 2.852 4.9417 2.679 14.2588
VMRC-LCD CTRP2; CTRP1 2.8959 4.6065 2.8047 13.5487
LXF 289 GDSC1; CTRP2; CTRP1 2.9005 4.4241 2.8414 13.6575
HCC15 GDSC1; CTRP2; CTRP1 2.9026 4.304 2.8606 13.5891
SK-MES-1 GDSC1; CTRP2 2.92 4.3339 2.6197 6.3396
HCC4006 CTRP2; CTRP1 2.9555 5.2775 2.7002 13.7252
Lu-99 CTRP2 3.0046 4.9291 2.8487 14.132
NCI-H841 GDSC1; CTRP2; CTRP1 3.0104 5.8053 2.5827 13.9796
NCI-H522 GDSC1; CTRP2 3.0727 7.179 1.4138 10.9322
NCI-H2286 CTRP2; CTRP1 3.0906 4.2584 3.065 13.1866
COR-L95 GDSC1; CTRP2 3.1032 4.1039 2.9068 4.7213
DMS 53 GDSC1; CTRP2 3.1432 5.6568 2.7751 13.1164
LUDLU-1 CTRP2 3.1601 4.1173 2.9613 4.3537
NCI-H2170 GDSC1; CTRP2 3.1644 4.852 2.6338 5.6599
NCI-H2196 GDSC1; CTRP2 3.1652 4.567 2.7679 5.1118
EBC-1 GDSC1; CTRP2 3.1788 4.4194 3.1388 11.7797
NCI-H3255 GDSC1; CTRP1 3.1812 5.4504 2.8908 12.6872
HCC44 GDSC1; CTRP2 3.1862 4.938 3.0445 12.0687
NCI-H2087 GDSC1; CTRP2 3.1969 5.0652 3.0225 12.1122
NCI-H2081 GDSC1; CTRP2; CTRP1 3.2137 6.3492 2.5894 13.4336
NCI-H211 GDSC1; CTRP2 3.2502 4.5847 3.1899 11.3995
NCI-H838 GDSC1; CTRP2 3.2594 5.0203 2.6446 5.3904
NCI-H1184 CTRP2 3.2609 5.5063 2.9548 12.9776
NCI-H1963 CTRP1 3.2622 9.4384 1.2369 36.8264
NCI-H1650 GDSC1; CTRP2 3.2968 6.0267 2.8014 12.6158
LK2 CTRP2 3.3126 3.9908 3.1735 3.1111
NCI-H23 GDSC1; CTRP2; CTRP1 3.3339 6.2678 2.7492 12.5625
NCI-H1573 GDSC1; CTRP2; CTRP1 3.3381 5.3794 3.0846 11.5829
NCI-H1666 GDSC1; CTRP2; CTRP1 3.3672 4.4473 3.3366 10.6537
DMS 454 CTRP2 3.3761 8.4782 1.7958 17.2081
HCC2279 CTRP2 3.3771 5.1097 3.2066 11.7065
NCI-H1092 GDSC1; CTRP2 3.382 6.9649 1.7958 8.6746
NCI-H446 GDSC1; CTRP2 3.3834 5.1977 3.1876 11.022
NCI-H1869 GDSC1; CTRP2 3.4371 5.4383 2.6033 5.1662
SK-LU-1 GDSC1; CTRP2; CTRP1 3.4601 6.5569 2.7601 12.429
DMS 273 GDSC1; CTRP2; CTRP1 3.496 4.8574 3.4038 9.875
A-549 GDSC1; CTRP2; CTRP1 3.5363 4.6271 3.4921 9.6423
NCI-H1944 GDSC1; CTRP2; CTRP1 3.5728 6.5815 2.866 11.5538
NCI-H82 GDSC1; CTRP1 3.6217 4.6915 3.5733 9.1231
HCC2935 CTRP2; CTRP1 3.6672 5.9173 3.2426 10.821
LC-1/sq-SF CTRP2 3.6701 4.5791 3.2356 2.0208
NCI-H2029 GDSC1; CTRP2; CTRP1 3.673 4.8957 3.5877 8.768
NCI-H2405 GDSC1; CTRP2; CTRP1 3.6759 8.3706 2.1453 14.2297
NCI-H2073 CTRP1 3.6964 5.3516 3.4828 21.0913
NCI-H2106 CTRP2 3.6973 8.1869 2.246 14.6328
HCC78 GDSC1; CTRP2 3.7668 6.428 3.1267 10.24
NCI-H1755 GDSC1; CTRP2; CTRP1 3.7765 5.2968 3.5878 8.6313
NCI-H2126 CTRP2 3.8329 5.5695 3.5491 9.1009
NCI-H1395 CTRP2 3.8431 5.5281 2.9026 3.1001
SW1271 GDSC1; CTRP2 3.8777 6.2577 3.315 9.2701
NCI-H1876 GDSC1; CTRP1 3.8801 5.7511 3.5342 8.5441
NCI-H1155 GDSC1; CTRP2 3.8853 6.11 3.3866 8.987
LOU-NH91 GDSC1; CTRP2 3.8929 5.7483 3.5441 8.3931
NCI-H1435 GDSC1; CTRP2; CTRP1 3.901 5.776 3.5466 8.4455
CAL-12T GDSC1; CTRP2; CTRP1 3.9063 5.9337 3.488 8.6446
HCC2108 CTRP2; CTRP1 3.9172 5.7784 3.5627 8.9009
NCI-H596 GDSC1; CTRP1 3.9236 5.3547 3.7282 7.74
NCI-H2009 GDSC1; CTRP2; CTRP1 3.9293 5.7496 3.5871 8.2262
NCI-H1339 CTRP2 3.9708 6.7224 2.4085 4.9496
NCI-H1373 CTRP2 3.9849 5.7738 3.6311 8.3642
NCI-H1563 GDSC1; CTRP2 4.0081 5.9792 3.5699 8.0068
NCI-H1105 CTRP2; CTRP1 4.0185 10.2831 1.5361 15.5125
NCI-H661 GDSC1; CTRP2 4.0254 6.5623 3.3293 8.8617
NCI-H1930 CTRP1 4.0715 10.067 1.6908 30.6233
NCI-H2122 GDSC1; CTRP2; CTRP1 4.1472 5.2788 3.9963 6.1944
NCI-H322 CTRP2 4.1695 6.9871 2.4297 4.5189
MOR/CPR CTRP2 4.177 5.7489 3.843 7.0197
COR-L279 CTRP2; CTRP1 4.2019 17.4477 -1.8635 25.5959
NCI-H1355 GDSC1; CTRP2; CTRP1 4.2144 6.3342 3.6295 7.3673
NCI-H292 GDSC1; CTRP2 4.2146 6.4186 3.5843 7.4558
NCI-H727 GDSC1; CTRP2 4.2191 6.54 3.5325 7.6414
RERF-LC-A1 CTRP2 4.2249 6.5177 3.5486 8.0714
ChaGo-K-1 GDSC1; CTRP2; CTRP1 4.2442 7.1938 3.2545 8.5753
HCC1588 CTRP2 4.271 5.4634 4.0579 5.9316
Calu-6 GDSC1; CTRP2; CTRP1 4.3058 6.2939 3.7393 6.7393
NCI-H1694 GDSC1; CTRP2; CTRP1 4.3083 6.7855 3.5113 7.6012
HOP-62 GDSC1; CTRP2 4.3285 6.5685 3.6265 7.034
HCC1438 CTRP2 4.337 5.9628 3.915 6.3163
COLO 668 GDSC1; CTRP2; CTRP1 4.3569 6.728 3.5856 7.0817
NCI-H889 CTRP2 4.3714 9.0119 2.4752 15.1532
NCI-H441 GDSC1; CTRP2; CTRP1 4.3746 5.7683 4.0456 5.4283
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 4.3758 6.9706 3.4799 7.4925
NCI-H1792 GDSC1; CTRP2; CTRP1 4.4248 5.992 3.9969 5.4895
Calu-3 GDSC1; CTRP2; CTRP1 4.453 6.1912 3.9329 5.6659
HCC366 CTRP2 4.4778 6.5766 3.7668 6.5742
NCI-H1623 GDSC1; CTRP2 4.4793 6.9277 2.6807 3.0071
NCI-H1836 GDSC1; CTRP1 4.4873 7.0146 3.5716 6.9783
T3M-10 CTRP2; CTRP1 4.4986 5.1034 4.4347 3.6422
RERF-LC-Ad1 CTRP2 4.5248 6.1433 4.0187 5.4313
NCI-H69 GDSC1; CTRP2 4.5253 6.731 3.7372 6.1745
SBC-5 GDSC1; CTRP2 4.5486 5.4175 4.37 3.7172
EPLC-272H GDSC1; CTRP2; CTRP1 4.5753 5.8003 4.2353 4.2381
LCLC-103H GDSC1; CTRP2 4.5934 11.7048 0.6918 13.1131
COR-L88 GDSC1; CTRP1 4.6264 5.8284 4.2732 3.976
NCI-H1299 GDSC1; CTRP2; CTRP1 4.6523 6.6774 3.89 5.394
NCI-H1437 GDSC1; CTRP1 4.6578 6.2088 4.123 4.4804
SCLC-21H CTRP1 4.6737 5.2566 4.5718 6.2995
COR-L51 CTRP1 4.6772 17.9623 -1.7136 37.7052
NCI-H2141 GDSC1; CTRP2; CTRP1 4.714 5.4968 4.5127 2.8173
SHP-77 GDSC1; CTRP2 4.7251 6.1994 4.1832 4.0197
NCI-H1915 GDSC1; CTRP2; CTRP1 4.7342 6.3353 4.1333 4.202
HCC1171 CTRP2 4.7449 7.281 3.6677 6.3921
DMS 114 GDSC1; CTRP2 4.7497 8.6693 2.9809 8.6798
NCI-H2172 GDSC1; CTRP2; CTRP1 4.7545 6.4962 4.0731 4.4691
HCC1833 CTRP2; CTRP1 4.7571 6.826 3.9127 5.4285
NCI-H526 GDSC1; CTRP2 4.7646 6.0263 4.3044 3.4654
LCLC-97TM1 GDSC1; CTRP2; CTRP1 4.789 6.2219 4.2395 3.7497
COLO 699 CTRP2; CTRP1 4.843 8.563 3.1239 8.5499
NCI-H1781 GDSC1; CTRP1 4.8506 6.5883 4.1143 4.1136
NCI-H2030 GDSC1; CTRP2; CTRP1 4.8551 6.6708 4.0774 4.2494
HCC1359 CTRP1 4.8845 5.8061 4.5316 5.527
Sq-1 CTRP2; CTRP1 4.9329 6.5856 4.1882 3.9068
NCI-H2023 GDSC1; CTRP2; CTRP1 5.0195 7.6266 3.7421 5.2563
NCI-H1838 GDSC1; CTRP2 5.02 7.9857 3.5533 5.9204
NCI-H650 GDSC1; CTRP2; CTRP1 5.0435 6.579 4.286 3.0709
HCC1195 CTRP2; CTRP1 5.0488 7.2488 3.9555 5.8224
NCI-H2228 GDSC1; CTRP2 5.0544 13.1526 0.9986 15.6294
NCI-H2291 GDSC1; CTRP2 5.115 8.218 3.5161 5.8961
RERF-LC-KJ GDSC1; CTRP1 5.1216 6.5254 4.3772 2.5725
KNS-62 CTRP2; CTRP1 5.1438 6.4327 4.4414 2.4337
Calu-1 CTRP2 5.1976 6.7874 4.297 2.8578
COR-L23 GDSC1; CTRP1 5.2141 6.2799 4.5724 1.6525
NCI-H460 GDSC1; CTRP2; CTRP1 5.2224 7.7884 3.8279 4.5589
HCC95 CTRP2 5.327 11.8608 1.8688 12.6973
NCI-H2110 GDSC1; CTRP2; CTRP1 5.5457 8.8141 3.57 4.9503
RERF-LC-Ad2 CTRP2 5.7526 14.5911 -0.1438 12.2611
NCI-H2342 GDSC1; CTRP2; CTRP1 5.8237 9.9393 3.223 5.8518
BEN GDSC1; CTRP2 6.0761 20.6813 -1.9318 22.6008
NCI-H2444 GDSC1; CTRP2 6.2449 18.6632 -0.7922 19.2773
NCI-H196 GDSC1; CTRP2 6.3515 10.3348 3.3933 4.4862
NCI-H1793 GDSC1; CTRP2 6.4486 10.7577 3.2563 4.8722
NCI-H226 GDSC1; CTRP2 6.7293 14.4254 1.6733 10.3895
NCI-H1651 GDSC1; CTRP2 6.9896 10.9283 3.5221 3.2583
Hs 888.Lu CTRP2 3.4067 6.464 2.0668 7.4839
⏷ Show the Full List of 217 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 -0.1031 3.383 -4.191 3.0008
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 0.0647 11.0189 -2.687 39.4219
OVKATE GDSC1; CTRP1 0.3195 4.1838 0.0967 30.2749
Caov-4 GDSC1 0.4705 3.5677 -4.0031 1.4704
ES-2 GDSC1 0.6049 2.3609 -3.5243 0.114
OVCAR-3 GDSC1 0.6471 2.5162 -3.5615 0.1511
OV7 CTRP2; CTRP1 1.9428 18.4641 -4.3898 35.1349
TOV-112D GDSC1; CTRP2 2.9171 5.1861 2.2345 7.892
OVCAR-5 GDSC1; CTRP2 3.3272 5.8994 2.8831 12.2431
A2780 GDSC1; CTRP2; CTRP1 3.4046 5.2364 3.2021 10.9936
IGROV-1 GDSC1; CTRP2; CTRP1 3.5108 5.9527 3.0627 11.1989
JHOS-2 GDSC1; CTRP2 3.5379 5.4132 2.7051 4.5259
TOV-21G GDSC1; CTRP2 3.605 5.3761 2.7818 4.0655
HEY A8 CTRP2; CTRP1 3.6073 5.2777 3.41 10.3606
SNU-119 CTRP2 3.6244 5.5883 3.3183 10.5666
COV434 CTRP2; CTRP1 3.6711 5.6047 3.3667 10.3369
JHOM-1 CTRP2; CTRP1 3.7105 6.2355 3.1571 10.1653
OAW28 GDSC1; CTRP2 3.7653 6.5592 3.0673 10.2806
OC 314 GDSC1; CTRP2 3.9267 6.1836 3.3977 8.8436
ONCO-DG-1 CTRP2 3.9578 8.2898 2.4463 13.2049
RMUG-S CTRP1 4.1071 6.935 3.2445 20.6058
OVTOKO GDSC1; CTRP2 4.1566 6.9224 3.2917 8.7012
FU-OV-1 GDSC1; CTRP2 4.1582 6.1097 3.6676 7.2761
OV-90 GDSC1; CTRP2; CTRP1 4.174 5.5799 3.9138 6.3032
JHOS-4 CTRP1 4.2715 5.7575 3.9434 13.8715
JHOC-5 CTRP2; CTRP1 4.3545 5.9383 3.95 6.2205
SK-OV-3 GDSC1; CTRP2; CTRP1 4.4046 6.2744 3.8464 6.1054
RMG-I GDSC1; CTRP2; CTRP1 4.4739 5.8975 4.0892 5.0263
OVCAR-4 GDSC1; CTRP2; CTRP1 4.5008 7.9467 3.127 8.6787
Caov-3 GDSC1; CTRP2; CTRP1 4.5277 6.1005 4.0488 5.0543
OVK18 GDSC1; CTRP2; CTRP1 4.5882 6.1444 4.0871 4.7717
TYK-nu GDSC1; CTRP2; CTRP1 4.6068 6.2889 4.0358 4.9276
OAW42 GDSC1; CTRP2; CTRP1 4.6084 5.1257 4.5475 2.9606
SNU-840 CTRP2; CTRP1 4.6354 6.8071 3.8109 6.1188
OVCAR-8 GDSC1; CTRP2; CTRP1 4.6517 7.1216 3.6712 6.2473
EFO-27 GDSC1; CTRP2; CTRP1 4.7095 7.7138 3.4301 6.9497
OVSAHO CTRP2 4.8703 6.375 3.5115 1.3484
DOV13 GDSC1; CTRP2 5.0373 10.0041 2.5586 9.7968
ES2 CTRP2 5.0505 11.2794 1.9319 12.9766
Kuramochi GDSC1; CTRP2 5.0779 7.8213 3.6838 5.3017
COV644 CTRP2; CTRP1 5.0851 6.0698 4.5751 1.8253
MCAS CTRP2 5.1161 15.0641 0.0942 19.6098
OV56 GDSC1; CTRP2 5.3677 7.5297 2.9319 1.1098
OVMANA CTRP1 5.4917 6.8625 4.4873 3.6115
COV362 CTRP2; CTRP1 5.6355 7.6943 4.1853 2.4819
COV318 CTRP1 5.7263 7.7364 4.2272 5.1392
EFO-21 GDSC1; CTRP2; CTRP1 5.8666 8.0152 4.1875 2.1771
SNU-8 CTRP2 6.5912 16.1811 0.7067 14.8089
OVISE GDSC1; CTRP2 10.1755 22.9013 -0.0558 11.5613
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 4.0495 8.9985 2.1874 14.0483
Aska-SS CTRP2 6.4114 8.1566 4.4258 0.8707
A-204 GDSC1; CTRP2 -3.579 6.1981 -4.7051 52.7631
G-402 GDSC1; CTRP2 -2.261 6.7447 -3.8318 42.7243
EW-8 GDSC1 0.0956 2.4826 -3.7508 0.7873
Rh30 GDSC1 0.1688 3.2299 -4.003 1.7392
VA-ES-BJ GDSC1 0.5199 2.3128 -3.5371 0.1414
SW684 GDSC1 0.5248 2.5297 -3.6082 0.246
SW872 GDSC1 0.5446 2.1821 -3.4857 0.0835
Hs 633.T GDSC1 0.6684 2.3658 -3.5048 0.0871
MFH-ino GDSC1 0.8151 2.853 -3.6165 0.195
G-401 GDSC1; CTRP2; CTRP1 1.9644 4.1329 1.8821 19.2294
TTC-709 CTRP2 2.6817 5.7391 2.2476 17.2981
TE 441.T GDSC1; CTRP2 2.942 3.9032 2.8097 5.5478
TE 617.T CTRP2 2.981 4.1052 2.7769 5.5616
Rh18 CTRP2 2.9953 4.9301 2.8383 14.1979
MES-SA GDSC1; CTRP2 3.0167 4.27 2.7475 5.5782
KYM-1 GDSC1; CTRP2 3.3232 6.5704 2.6066 13.2567
Hs 729.T CTRP2 3.3474 8.1366 1.1817 11.3143
BT-16 CTRP2 3.4552 6.5387 2.7571 13.1987
GCT GDSC1; CTRP2 3.5222 5.5547 3.2204 10.5267
RD GDSC1; CTRP2 3.5866 4.9588 2.974 3.2933
SK-LMS-1 GDSC1; CTRP2 3.6317 5.0879 2.9486 3.3084
Rh41 GDSC1; CTRP2 3.9001 8.7977 2.1457 13.6599
SK-UT-1 GDSC1; CTRP2 3.9597 7.4579 2.0332 6.5479
RKN GDSC1; CTRP2; CTRP1 4.7599 11.2912 1.6902 13.7205
HT-1080 GDSC1; CTRP2; CTRP1 5.0205 6.1634 4.4743 2.3302
Tm87-16 CTRP2 5.1895 7.9805 3.6955 5.3959
BT-12 CTRP2 5.6081 8.8079 3.6093 5.0277
SW982 GDSC1; CTRP2 6.5912 7.7523 4.6641 0.1722
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 4.0915 7.9871 2.7192 11.7785
P-STS CTRP2 5.1403 13.799 -0.2048 13.4821
H-STS CTRP2 5.3475 12.1965 0.7345 9.5604
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.2036 6.721 2.5862 3.8119
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1 -0.1481 1.9291 -3.6448 0.5851
IST-Mes1 GDSC1; CTRP2 2.4175 7.283 0.7531 15.1369
MSTO-211H GDSC1; CTRP2; CTRP1 2.4249 4.3634 2.34 16.7085
JL-1 CTRP2 3.6347 5.7468 2.6219 4.6798
NCI-H28 GDSC1; CTRP2; CTRP1 3.9665 5.9058 3.5627 8.2195
NCI-H2452 GDSC1; CTRP2 4.4963 7.5316 3.319 7.8607
NCI-H2052 GDSC1; CTRP2; CTRP1 4.8382 8.2042 3.2988 7.3393
ACC-MESO-1 CTRP2 5.3975 14.1979 0.7585 16.7754
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1 1.0951 3.3009 -3.6704 0.2177
LNCaP clone FGC GDSC1; CTRP2 2.9167 6.411 1.6471 10.3114
DU145 GDSC1; CTRP2 3.072 5.5266 2.2223 7.572
VCaP GDSC1; CTRP2 3.1163 4.5181 2.7411 5.3429
PaCa-3 CTRP2; CTRP1 4.4045 6.5868 3.6989 6.5513
22Rv1 GDSC1; CTRP2 4.8284 7.5224 3.6211 6.0123
NCI-H660 CTRP2 5.1796 7.4576 3.9486 4.3518
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 3.6525 4.772 3.5901 9.4871
A-253 GDSC1; CTRP2 4.1878 7.376 2.2513 5.2326
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 0.4864 2.711 -3.6842 0.4114
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 GDSC1; CTRP2 -1.1708 1.1987 -1.1941 32.6561
HSC-39 GDSC1 -0.6931 4.2867 -4.9185 8.5509
RERF-GC-1B GDSC1 -0.038 3.866 -4.3606 3.8624
SCH GDSC1 0.0765 1.6206 -3.4575 0.115
RF-48 GDSC1 0.2674 3.247 -3.9668 1.4901
MKN28 GDSC1 0.3584 2.89 -3.7962 0.7819
TGBC11TKB GDSC1 0.4767 2.7348 -3.696 0.4429
OCUM-1 GDSC1 0.5243 2.669 -3.6559 0.3368
GCIY GDSC1 0.7324 3.0953 -3.7283 0.4245
TMK-1 GDSC1 0.7922 2.7247 -3.5816 0.1522
HGC-27 GDSC1; CTRP2 2.2047 5.0688 1.9387 18.6096
SNU-1 GDSC1; CTRP2 2.5302 5.7394 1.5946 11.4469
IM95 GDSC1; CTRP2 2.5551 4.4513 2.1878 9.018
GSS CTRP2 2.8707 4.4742 2.8 14.7228
SNU-216 CTRP2 3.0581 5.1451 2.8484 13.9697
HuG1-N CTRP2 3.1475 4.4999 2.7808 5.1043
NCI-N87 GDSC1; CTRP2 3.2043 4.6925 3.1202 11.7641
Hs 746.T GDSC1; CTRP2 3.2338 4.0701 3.058 3.7758
Fu97 GDSC1; CTRP2; CTRP1 3.5083 7.0387 2.5982 12.9113
SNU-620 CTRP2 3.6024 4.3667 3.5916 9.6432
SNU-668 CTRP2 3.6863 5.1818 3.5226 9.6259
SNU-719 CTRP2 3.7266 4.797 3.6655 8.9891
KE-39 CTRP2 3.9915 6.3497 3.391 9.2913
23132/87 GDSC1; CTRP2 4.071 6.5161 3.3961 8.5026
ECC10 GDSC1; CTRP2 4.104 5.2602 3.9521 6.3823
SNU-5 GDSC1; CTRP2 4.1238 5.264 3.9722 6.2582
SH-10-TC CTRP2; CTRP1 4.1616 5.5539 3.9109 6.3451
NUGC-4 GDSC1; CTRP2; CTRP1 4.2083 5.4868 3.9866 6.0651
AGS GDSC1; CTRP2; CTRP1 4.21 5.1049 4.1195 5.5951
MKN74 CTRP2; CTRP1 4.8464 6.4674 4.1705 3.8332
MKN7 GDSC1; CTRP2; CTRP1 4.8549 7.2493 3.7893 5.2856
SNU-601 CTRP2 5.0585 8.9649 3.0959 8.1606
MKN1 GDSC1; CTRP2 5.0924 7.0004 4.1061 3.6118
LMSU CTRP2 5.2695 23.4498 -4.899 26.3126
GSU CTRP2 5.3738 10.2833 2.6941 9.2459
NUGC-3 GDSC1; CTRP2 5.5404 7.5411 4.1814 2.6016
ECC12 CTRP2 5.9233 8.6942 3.8898 3.3958
MKN45 GDSC1; CTRP2 6.1894 15.6235 -0.0364 13.115
SNU-1077 CTRP2 2.8089 5.0645 2.5992 15.6275
SNU-685 CTRP2 3.5678 5.4163 2.7296 4.361
SNG-M GDSC1; CTRP2; CTRP1 4.7571 6.4928 4.0771 4.4481
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 -3.1923 21.1487 -11.271 48.7312
CGTH-W-1 GDSC1; CTRP2 -1.5994 5.4847 -2.331 42.8383
WRO GDSC1 0.4052 3.4938 -4.0026 1.5231
HTC-C3 GDSC1 0.4442 2.8161 -3.7367 0.561
ASH-3 GDSC1 0.4657 5.022 -4.5924 4.4291
KMH-2 GDSC1 0.4682 2.5606 -3.6387 0.3189
IHH-4 GDSC1 0.503 2.7077 -3.677 0.3892
K5 GDSC1 0.9175 2.8172 -3.5699 0.1204
8505C GDSC1; CTRP2 3.5562 7.1357 2.5966 12.726
TT GDSC1; CTRP2 3.8232 6.0334 3.3542 9.2615
FTC-133 GDSC1; CTRP2 4.0243 6.9862 2.319 5.2308
TT2609-C02 GDSC1; CTRP2 4.1238 6.0658 2.8494 2.8494
8305C GDSC1; CTRP2 4.1973 6.599 3.4834 7.8781
FTC-238 CTRP2 4.3083 6.6423 2.7002 3.1783
BHT-101 GDSC1; CTRP2 4.4829 5.5609 4.2411 4.3544
ML-1 [Human leukemia] GDSC1; CTRP2 4.7816 9.3149 2.6864 9.7729
B-CPAP GDSC1; CTRP2 4.8214 12.4978 1.1303 15.5964
CAL-62 GDSC1; CTRP2 5.3894 7.2125 4.2327 2.6258
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HO-1-u-1 GDSC1 0.0022 3.4934 -4.1853 2.8326
PCI-06A GDSC1 0.1093 2.8052 -3.8653 1.2009
PCI-38 GDSC1 0.1508 2.5231 -3.7439 0.732
KOSC-2 GDSC1 0.1543 2.7093 -3.8108 0.9598
SAS GDSC1 0.2444 2.4273 -3.6738 0.481
OSC-20 GDSC1 0.2827 2.6695 -3.7457 0.6655
SCC-15 GDSC1 0.2875 2.5401 -3.6976 0.5252
Ca9-22 GDSC1 0.3379 2.9067 -3.8103 0.8405
SKN-3 GDSC1 0.3401 2.6207 -3.7065 0.5259
BICR 78 GDSC1 0.3586 3.0354 -3.8493 0.9617
BB30-HNC GDSC1 0.4308 2.708 -3.7035 0.4796
JHU-022 GDSC1 0.4858 3.0903 -3.8192 0.7836
PCI-15A GDSC1 0.5012 2.7583 -3.6953 0.4319
BICR 10 GDSC1 0.5301 2.5454 -3.6116 0.2508
JHU-011 GDSC1 0.6134 2.9619 -3.7253 0.4611
OSC-19 GDSC1 0.6173 2.3609 -3.5201 0.1079
NCI-H3118 GDSC1 0.6272 3.3141 -3.8454 0.7877
PCI-04B GDSC1 0.6282 3.1853 -3.7987 0.6478
LB771-HNC GDSC1 0.653 2.8726 -3.68 0.3463
KON GDSC1 0.6543 2.9184 -3.6953 0.3782
SAT [Human HNSCC] GDSC1 0.6669 3.5613 -3.92 1.0103
PCI-30 GDSC1 0.682 3.3243 -3.828 0.7062
DOK GDSC1 0.6848 3.4426 -3.8695 0.8319
BB49-HNC GDSC1 0.6981 2.8592 -3.6593 0.2928
HO-1-N-1 GDSC1 0.7403 2.5908 -3.5547 0.1284
BICR 18 CTRP2 1.8106 4.8262 1.2499 14.7035
YD-10B CTRP2 2.6996 3.5908 2.6972 15.6294
YD-8 CTRP2 2.9777 4.6306 2.8869 17.6237
PE/CA-PJ34 (clone C12) CTRP2 3.0159 4.6952 2.5597 6.328
HSC-2 GDSC1; CTRP2; CTRP1 3.2164 4.6642 3.1405 11.535
PE/CA-PJ49 CTRP2 3.224 4.5892 2.8158 4.7718
BICR 6 CTRP2 3.3172 6.2859 2.076 7.6349
PE/CA-PJ41 (clone D2) CTRP2 3.5992 4.9255 3.0017 3.1507
BICR 31 GDSC1; CTRP2 3.6017 4.6022 3.1649 2.4587
Detroit 562 GDSC1; CTRP2 3.6097 5.4597 2.9715 5.6859
SNU-1214 CTRP2 3.6664 5.3664 3.4418 9.9826
BICR 22 GDSC1; CTRP2 3.732 4.5767 3.2883 1.6786
SNU-1076 CTRP2 3.7341 5.5435 3.4526 9.7467
PE/CA-PJ15 GDSC1; CTRP2 3.8601 6.5915 2.3857 5.2458
CAL-33 GDSC1; CTRP2 3.8787 5.5045 3.6224 8.1503
FaDu GDSC1; CTRP2 3.8868 6.0448 2.6797 3.9593
SNU-899 CTRP2 4.0118 5.506 3.7647 7.7769
HSC-4 GDSC1; CTRP2 4.0128 6.9229 3.1503 9.5676
SNU-46 CTRP2 4.0141 5.2048 3.8725 7.3664
SCC-25 GDSC1; CTRP2 4.0281 5.2139 3.8847 6.8252
BHY GDSC1; CTRP2 4.1398 10.4129 1.5734 15.3188
CAL-27 GDSC1; CTRP2 4.224 7.1534 2.3885 4.6005
SNU-1041 CTRP2 4.8194 6.8843 3.2419 2.5257
SCC-9 GDSC1; CTRP2; CTRP1 4.861 7.0365 3.9007 4.8445
SNU-1066 CTRP2 4.8906 8.6946 2.4142 6.0076
HSC-3 GDSC1; CTRP2 5.5079 10.7512 1.8523 6.9462
BICR 56 CTRP2 5.5557 6.9417 4.4805 1.5459
SCC-4 GDSC1; CTRP2 5.8671 7.4962 4.4173 1.3195
BICR 16 CTRP2 6.4038 8.4806 4.2832 1.341
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-1 CTRP2 0.6119 4.0341 0.2332 21.9936
SW780 GDSC1 0.6532 2.2882 -3.4844 0.0716
JMSU-1 CTRP2 1.1959 4.4372 0.9932 26.3324
RT-4 GDSC1; CTRP2; CTRP1 2.3632 4.875 2.1651 17.4668
J82 GDSC1; CTRP2 2.8201 5.9288 1.7883 9.9529
RT-112 GDSC1; CTRP2 3.2938 6.0333 2.7956 12.6444
253J CTRP2 3.3382 4.9331 3.2115 11.8074
U-BLC1 CTRP2 3.6479 5.4135 3.4057 10.1712
HT-1376 GDSC1; CTRP2; CTRP1 3.7369 6.0905 3.2455 9.9574
SCaBER CTRP2 3.8178 6.4496 2.4224 5.1696
SW1710 GDSC1; CTRP2 3.9398 6.4735 3.2831 9.2384
HT-1197 GDSC1; CTRP2 3.9698 7.0565 2.2413 5.6545
5637 GDSC1; CTRP2; CTRP1 4.0507 5.1361 3.9366 6.668
TCCSUP GDSC1; CTRP2 4.1994 7.7597 2.9312 9.9932
T24 GDSC1; CTRP2 4.389 9.8135 1.1971 9.2726
KU-19-19 GDSC1; CTRP2 4.4078 10.6928 1.6736 14.4
VM-CUB-1 CTRP2 4.4539 6.8257 3.624 7.2172
KMBC-2 CTRP2; CTRP1 4.846 6.7759 4.0171 4.8032
BFTC-905 GDSC1; CTRP2 4.8723 6.5155 4.1609 3.8062
UM-UC-3 GDSC1; CTRP2; CTRP1 4.9406 6.9996 3.9883 4.4341
253J-BV CTRP2 4.9897 6.4717 4.2847 3.3004
CAL-29 GDSC1; CTRP2 5.0549 6.6705 4.2401 3.1508
639V GDSC1; CTRP2 5.1435 10.2795 2.5089 9.799
647V GDSC1; CTRP2 5.1593 8.3981 2.4275 3.1153
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVCA433 GDSC1 -0.1439 2.8292 -3.9853 1.9753
LB831-BLC GDSC1 -0.0789 2.837 -3.959 1.78
SiSo GDSC1 -0.0044 3.6521 -4.2541 3.2145
C-4-I GDSC1 0.0456 1.8924 -3.56 0.288
BPH-1 GDSC1 0.0724 4.3026 -4.4894 4.4376
SW756 GDSC1 0.0917 1.9792 -3.5733 0.3013
Ca Ski GDSC1 0.0922 4.5022 -4.5646 4.8447
SKN GDSC1 0.1409 3.8527 -4.2659 3.0858
DoTc2 4510 GDSC1 0.1902 2.1193 -3.5863 0.2973
OVMIU GDSC1 0.2345 3.3614 -4.0254 1.7778
PA-1 GDSC1 0.2436 3.1932 -3.9564 1.4662
NCC-IT GDSC1 0.3141 5.7123 -4.9724 6.8644
DSH1 GDSC1 0.3611 2.5359 -3.6689 0.4218
OMC-1 [Human cervical carcinoma] GDSC1 0.3859 2.3411 -3.5928 0.2543
NT2-D1 GDSC1 0.4055 2.7603 -3.7315 0.5641
HEY GDSC1 0.409 3.2526 -3.9097 1.148
ME-180 GDSC1 0.4142 3.3506 -3.9443 1.2779
MS751 GDSC1 0.4302 2.385 -3.5922 0.2419
HEC-1 GDSC1 0.4458 2.3715 -3.5822 0.2211
C-33 A GDSC1 0.4823 2.4736 -3.604 0.2494
KGN GDSC1 0.4889 3.7986 -4.084 1.8009
PEO1 GDSC1 0.5112 2.7645 -3.6938 0.4246
JHOS-3 GDSC1 0.5953 2.7128 -3.6457 0.2955
HT-3 GDSC1 0.5977 3.4513 -3.9071 1.0098
SKG-IIIa GDSC1 0.6046 2.685 -3.6329 0.2695
SW962 GDSC1 0.6152 2.9708 -3.7277 0.4664
SiHa GDSC1 0.6376 2.1288 -3.4379 0.0418
NEC8 GDSC1 0.645 2.1261 -3.4346 0.0396
JAR GDSC1 0.6546 2.6529 -3.6046 0.2103
OVCA420 GDSC1 0.6789 2.3953 -3.5109 0.0915
ACC-OV7 GDSC1 0.6882 3.6039 -3.9272 1.0218
UWB1.289 GDSC1 0.728 3.622 -3.918 0.9654
JEG-3 GDSC1 0.7715 2.7438 -3.5949 0.1732
SW954 GDSC1 1.1089 3.8035 -3.8378 0.5423
CAL-39 GDSC1 1.1101 3.2044 -3.6331 0.1644
OV17R GDSC1 1.1118 3.5338 -3.7434 0.3365
HeLa GDSC1; CTRP2 4.4782 6.2598 3.9183 5.4831
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services
2 FDA Approved Drug Products: FOTIVDA (tivozanib) capsules, for oral use
3 Cotreau MM, Hale CL, Jacobson L, Oelke CS, Strahs AL, Kochan RG, Sanga M, Slichenmyer W, Vargo DL: Absorption, Metabolism, and Excretion of [(14) C]-Tivozanib, a Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, in Healthy Male Participants: A Phase I, Open-Label, Mass-Balance Study. Clin Pharmacol Drug Dev. 2012 Jul;1(3):102-9. doi: 10.1177/2160763X12447303.