Details of the Drug

General Information of Drug (ID: DMUOXHP)

Drug Name
3,4-dihydroquinazolin-2-amine hydrobromide
Synonyms CHEMBL557381; SCHEMBL2386507; RXCXYMVUYRKQAO-UHFFFAOYSA-N; 1,4-dihydro-quinazolin-2-ylamine monohydrobromide
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski):
0		 Molecular Weight 228.09
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 0
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 1
Chemical Identifiers
Formula
C8H10BrN3
IUPAC Name
1,4-dihydroquinazolin-2-amine;hydrobromide
Canonical SMILES
C1C2=CC=CC=C2NC(=N1)N.Br
InChI
InChI=1S/C8H9N3.BrH/c9-8-10-5-6-3-1-2-4-7(6)11-8;/h1-4H,5H2,(H3,9,10,11);1H
InChIKey
RXCXYMVUYRKQAO-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
45263885
ChEBI ID
CHEMBL557381
TTD ID
D0I6II
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 5A receptor (HTR5A) TTRUFDT 5HT5A_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: structure-activity relationship elucidation. Bioorg Med Chem Lett. 2008 Jan 1;18(1):256-61.