Details of the Drug

General Information of Drug (ID: DMUOXHP)

Drug Name
3,4-dihydroquinazolin-2-amine hydrobromide
Synonyms CHEMBL557381; SCHEMBL2386507; RXCXYMVUYRKQAO-UHFFFAOYSA-N; 1,4-dihydro-quinazolin-2-ylamine monohydrobromide
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski):
0		 Molecular Weight 228.09
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 0
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 1
Chemical Identifiers
Formula
C8H10BrN3
IUPAC Name
1,4-dihydroquinazolin-2-amine;hydrobromide
Canonical SMILES
C1C2=CC=CC=C2NC(=N1)N.Br
InChI
InChI=1S/C8H9N3.BrH/c9-8-10-5-6-3-1-2-4-7(6)11-8;/h1-4H,5H2,(H3,9,10,11);1H
InChIKey
RXCXYMVUYRKQAO-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
45263885
TTD ID
D0I6II

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 5A receptor (HTR5A) TTRUFDT 5HT5A_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: structure-activity relationship elucidation. Bioorg Med Chem Lett. 2008 Jan 1;18(1):256-61.