Details of the Drug

General Information of Drug (ID: DMVB1PD)

Drug Name
GRL-001
Synonyms CE-5
Indication
Disease Entry ICD 11 Status REF
Middle East Respiratory Syndrome (MERS) 1D64 Preclinical [1]
Severe acute respiratory syndrome (SARS) 1D65 Preclinical [1]
Therapeutic Class
Antiviral Agents
Drug Type
Small molecular drug
Structure 3D Structure is Not Available
3D MOL 2D MOL
Cross-matching ID
TTD ID
D0RV9C
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
MERS-CoV 3C-like proteinase (3CLpro) TTWOH4Q R1AB_CVEMC (3248-3553) Inhibitor [1]
SARS-CoV 3C-like protease (3CLpro) TTPZG3C R1AB_CVHSA (3241-3546) Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 May;15(5):327-47.