Details of the Drug

General Information of Drug (ID: DMVEEP9)

Drug Name

MK-7285

Synonyms

Prostaglandin E2 synthase inhibitors (inflammation), Merck Frosst; MK-886 derivatives (inflammation), Merck Frosst; Prostaglandin E2 synthase inhibitors (inflammation), Merck & Co; M-PGES-1 inhibitors (inflammation), Merck Frosst; MK-886 derivatives (inflammation), Merck & Co; M-PGES-1 inhibitors (inflammation), Merck & Co

Indication

Disease Entry	ICD 11	Status	REF
Inflammation	1A00-CA43.1	Investigative	[1]

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C32H27FN4O2
Canonical SMILES: CC(C)(CC1=CC2=C(C=C1)C3=C(C4=C2C=C(C=C4)OCCC5CC5)N=C(N3)C6=C(C=C(C=C6C#N)F)C#N)O
InChI: InChI=1S/C32H27FN4O2/c1-32(2,38)15-19-5-7-24-26(11-19)27-14-23(39-10-9-18-3-4-18)6-8-25(27)30-29(24)36-31(37-30)28-20(16-34)12-22(33)13-21(28)17-35/h5-8,11-14,18,38H,3-4,9-10,15H2,1-2H3,(H,36,37)
InChIKey: PYRKKGOKRMZEIT-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 16730275
ChEBI ID: CHEMBL565406
TTD ID: D0W6TB

Drug-Molecule Activity Atlas (DMA)^NEW

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References

1	The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.