General Information of Drug (ID: DMVGAI4)

Drug Name
DYN101
Indication
Disease Entry ICD 11 Status REF
Congenital structural myopathy 8C72.0 Phase 1/2 [1]
Drug Type
Antisense oligonucleotide
Cross-matching ID
DrugBank ID
DB17921
TTD ID
D1ZAW4

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNM2 messenger RNA (DNM2 mRNA) TTVRA5G DYN2_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04033159) A Phase 1/2 Trial on the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Exploratory Efficacy of DYN101 in Patients >= 16 Years of Age With Centronuclear Myopathies Caused by Mutations in DNM2 or MTM1. U.S.National Institutes of Health.
2 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2023. Adis Insight