Details of the Drug

General Information of Drug (ID: DMVTKJZ)

Drug Name
BMS-820836
Synonyms
Liafensine; BMS-820836; UNII-R34ID086Z6; 1198790-53-2; R34ID086Z6; Liafensine [USAN:INN]; Liafensine (USAN); BMS 820836; SCHEMBL1120067; CHEMBL2364614; DTXSID60152610; VCIBGDSRPUOBOG-QFIPXVFZSA-N; AKOS032946316; D10443; 6-[(4s)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine; (S)-6-(2-methyl-4-(naphthalen-2-yl)-1,2,3,4-tetrahydroisoquinolin-7-yl)pyridazin-3-amine; (5)-6-(2-methyl-4-(naphthalen-2-yl)-1,2,3,4-tetrahydroisoquinolin-7-yl)pyridazin-3-amine; 3-Pyridazinamine, 6-((4S)-1,2,3,4-tetrahydr
Indication
Disease Entry ICD 11 Status REF
Major depressive disorder 6A70.3 Phase 2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C24H22N4
Canonical SMILES
CN1CC(C2=C(C1)C=C(C=C2)C3=NN=C(C=C3)N)C4=CC5=CC=CC=C5C=C4
InChI
InChI=1S/C24H22N4/c1-28-14-20-13-19(23-10-11-24(25)27-26-23)8-9-21(20)22(15-28)18-7-6-16-4-2-3-5-17(16)12-18/h2-13,22H,14-15H2,1H3,(H2,25,27)/t22-/m0/s1
InChIKey
VCIBGDSRPUOBOG-QFIPXVFZSA-N
Cross-matching ID
PubChem CID
58212050
ChEBI ID
CHEMBL2364614
CAS Number
1198790-53-2
UNII
R34ID086Z6
DrugBank ID
DB14878
TTD ID
D0J9PT
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug

References

1 Evaluation of safety and tolerability, pharmacokinetics, and pharmacodynamics of BMS-820836 in healthy subjects: a placebo-controlled, ascending single-dose study. Psychopharmacology (Berl). 2014 Jun;231(11):2299-310.