Details of the Drug

General Information of Drug (ID: DMVX063)

Drug Name
5-QUINOXALIN-6-YLMETHYLENE-THIAZOLIDINE-2,4-DIONE
Synonyms
5-Quinoxalin-6-ylmethylene-thiazolidine-2,4-dione; AS-605240; 648450-29-7; AS605240; AS 605240; CHEMBL568150; (5Z)-5-(quinoxalin-6-ylmethylidene)-1,3-thiazolidine-2,4-dione; (5E)-5-(QUINOXALIN-6-YLMETHYLENE)-1,3-THIAZOLIDINE-2,4-DIONE; 5-(6-QUINOXALINYLMETHYLENE)-2,4-THIAZOLIDINEDIONE; QYT; (Z)-5-(Quinoxalin-6-ylmethylene)thiazolidine-2,4-dione; PI 3-Kg inhibitor; 2a5u; AC1NRCY0; 5-(quinoxalin-6-ylmethylene)thiazolidine-2,4-dione; SCHEMBL668616; GTPL6023; AOB3848; MolPort-006-169-944; HMS3650I15
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 257.269
Logarithm of the Partition Coefficient (xlogp) 1.5
Rotatable Bond Count (rotbonds) 1
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C12H7N3O2S
IUPAC Name
(5Z)-5-(quinoxalin-6-ylmethylidene)-1,3-thiazolidine-2,4-dione
Canonical SMILES
C1=CC2=NC=CN=C2C=C1/C=C\\3/C(=O)NC(=O)S3
InChI
InChI=1S/C12H7N3O2S/c16-11-10(18-12(17)15-11)6-7-1-2-8-9(5-7)14-4-3-13-8/h1-6H,(H,15,16,17)/b10-6-
InChIKey
SQWZFLMPDUSYGV-POHAHGRESA-N
Cross-matching ID
PubChem CID
5289247
ChEBI ID
CHEBI:45302
DrugBank ID
DB04769
TTD ID
D08NQM

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Monoamine oxidase type B (MAO-B) TTGP7BY AOFB_HUMAN Inhibitor [2]
PI3-kinase gamma (PIK3CG) TTHBTOP PK3CG_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Monoamine oxidase type B (MAO-B) DTT MAOB 2.65E-02 1.12E-02 0.07
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 3.9077 4.8088 3.6833 6.7695
EW-1 GDSC1 1.6785 8.1618 -0.0829 40.1079
NOS-1 [Human HNSCC] GDSC1 1.7644 7.3582 0.3654 38.3522
EW-13 GDSC1 1.8637 3.8003 1.7615 31.3643
CADO-ES1 GDSC1 2.1924 5.127 1.7372 29.5008
HuO9 GDSC1 2.2797 10.3953 -0.5485 38.1182
EW-11 GDSC1 2.3595 5.1298 1.9158 27.4154
ES5 GDSC1 2.442 5.0598 2.0303 26.206
ES7 GDSC1 2.8214 5.7523 2.1539 23.3175
ES6 GDSC1 3.0649 8.8442 0.9434 29.1363
TC-71 GDSC1 3.3639 9.2315 1.0292 27.3521
EW-3 GDSC1 3.5394 6.6077 2.4757 17.5669
SJSA-1 GDSC1 3.5927 8.9223 1.3889 24.4389
EW-7 GDSC1 3.5951 9.1164 1.2949 24.9507
EW-18 GDSC1 3.6445 6.4809 2.6365 15.9124
MHH-ES-1 GDSC1 3.7633 13.0895 -0.5357 31.9064
SK-ES-1 GDSC1 3.8185 7.6516 2.221 18.1927
ES4 GDSC1 3.8423 8.1981 1.9709 19.8034
EW-16 GDSC1 3.9173 5.3478 3.4423 8.5563
ES8 GDSC1 3.9978 4.9178 3.7242 6.0362
CHSA0108 GDSC1 4.15 5.6098 3.5297 6.9002
A-673 GDSC1 4.2205 12.9624 -0.0831 28.7094
ES1 GDSC1 4.2329 6.1125 3.3514 7.9822
SK-PN-DW GDSC1 4.2593 5.413 3.7234 4.9523
H-EMC-SS GDSC1 4.5337 10.0536 1.6306 19.2986
EW-24 GDSC1 5.0081 6.6552 3.6655 3.1553
HOS GDSC1 5.0119 6.3427 3.8122 2.1022
CHSA0011 GDSC1 5.6651 12.4748 1.3036 17.5047
MG-63 GDSC1 5.9381 7.6436 3.737 1.1399
U2OS GDSC1 6.1452 8.7336 3.3863 2.8365
NY GDSC1 6.2835 10.1182 2.8494 5.4407
CAL-72 GDSC1 6.3988 7.8405 3.8534 0.3391
CHSA8926 GDSC1 6.4678 8.1717 3.7604 0.5907
HuO-3N1 GDSC1 6.5869 8.9383 3.5175 1.5207
CAL-78 GDSC1 6.9409 8.6837 3.7577 0.3199
SaOS-2 GDSC1 7.1865 8.9823 3.7432 0.3024
G-292 clone A141B1 GDSC1 7.2156 8.9393 3.7684 0.2161
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 146 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 3.8958 4.4979 3.7993 5.9827
SIG-M5 GDSC1 -5.0565 -2.6156 -5.057 96.4762
NB4 GDSC1 -4.5573 1.4318 -4.7594 82.7238
OCI-AML-2 GDSC1 -3.6755 -2.246 -3.6755 94.3468
KMOE-2 GDSC1 -3.3017 -0.0978 -3.3173 84.9597
OCI-AML-3 GDSC1 -2.8212 2.8068 -3.1183 73.9168
OCI-Ly19 GDSC1 -2.5398 3.8611 -3.0458 70.2544
ML-2 GDSC1 -2.4978 3.7562 -2.9741 70.3039
OCI-M1 GDSC1 -1.5037 3.3426 -1.7976 65.976
ME1 GDSC1 -1.2062 22.6898 -9.796 53.4682
OCI-AML-5 GDSC1 -1.1141 3.0478 -1.3176 63.8165
Kasumi-1 GDSC1 -0.8519 6.2032 -1.9305 58.0536
MOLT-16 GDSC1 -0.6357 0.9778 -0.6374 61.8361
ALL-PO GDSC1 -0.5791 6.7204 -1.8304 56.0384
JURL-MK1 GDSC1 -0.551 2.5439 -0.637 59.6419
697 GDSC1 -0.524 2.1981 -0.5726 59.7116
KE-37 GDSC1 -0.4448 1.6391 -0.4572 59.2758
Loucy GDSC1 -0.4303 1.0347 -0.4313 59.3455
PL-21 GDSC1 -0.341 7.0392 -1.7008 54.4134
SUP-B15 GDSC1 -0.334 2.1055 -0.367 57.7406
HAL-01 GDSC1 -0.204 4.6895 -0.7224 54.6919
MEG-01 GDSC1 -0.2012 4.2362 -0.5911 54.9412
YT GDSC1 0.0548 11.1211 -3.0632 51.2603
SU-DHL-8 GDSC1 0.1055 11.8558 -3.3526 50.9671
JSC-1 GDSC1 0.1422 11.4416 -3.124 50.8322
RPMI-8402 GDSC1 0.1779 1.5304 0.1764 51.7951
QIMR-WIL GDSC1 0.2395 4.6546 -0.2284 50.7824
SUP-T1 GDSC1 0.3127 4.4645 -0.0932 50.0903
A3/Kawakami GDSC1 0.4723 8.009 -1.2476 49.0133
NKM-1 GDSC1 0.5631 5.9272 -0.3082 47.967
NOMO-1 GDSC1 0.568 4.9336 0.0432 47.65
MOLP-8 GDSC1 0.6914 5.5839 -0.0445 46.6997
LAMA-84 GDSC1 0.7784 5.6497 0.0254 45.9142
WIL2 NS GDSC1 0.9973 5.0607 0.4681 43.3263
DND-41 GDSC1 1.0383 5.5232 0.3511 43.2867
THP-1 GDSC1 1.0483 4.2823 0.7601 42.0828
PF-382 GDSC1 1.1476 4.2316 0.8819 40.863
NALM-6 GDSC1 1.3437 11.192 -1.8279 44.6705
Karpas-45 GDSC1 1.4282 4.5117 1.1101 37.8172
RPMI-6666 GDSC1 1.4419 4.6692 1.0776 37.8637
EB2 GDSC1 1.4923 4.6522 1.1378 37.2355
ALL-SIL GDSC1 1.5316 4.932 1.0907 37.1734
GDM-1 GDSC1 1.7149 5.0388 1.2532 35.1651
VL51 GDSC1 1.7451 7.6197 0.2293 38.8792
Hs 445 GDSC1 1.7757 6.7578 0.6394 37.3616
CTB-1 GDSC1 1.8746 11.2248 -1.3336 41.5708
H9 GDSC1 1.9415 10.1422 -0.7503 40.2001
MOLM-13 GDSC1 1.9592 6.6673 0.8681 35.3497
SUP-M2 GDSC1 1.9794 5.9052 1.209 33.6895
P12-Ichikawa GDSC1 2.0011 6.7229 0.8873 35.0171
MOLT-13 GDSC1 2.0055 5.184 1.5154 31.9244
HL-60 GDSC1 2.0941 7.7803 0.5083 35.9521
MY-M12 GDSC1 2.114 8.9477 -0.0158 37.5334
WSU-NHL GDSC1 2.1199 12.7302 -1.8337 41.2749
MN-60 GDSC1 2.1675 4.6871 1.8618 28.8809
Mono-Mac-6 GDSC1 2.1989 8.8985 0.0901 36.7742
SU-DHL-10 GDSC1 2.2465 3.1576 2.2409 25.9779
ATN-1 GDSC1 2.427 5.9559 1.6575 28.6232
MLMA GDSC1 2.4334 7.7672 0.8516 32.7224
EM-2 GDSC1 2.493 10.0144 -0.1625 36.0701
BC-1 GDSC1 2.5328 9.7311 0.0123 35.3452
LC4-1 GDSC1 2.5378 8.7559 0.4861 33.6697
KG-1 GDSC1 2.6688 9.6871 0.162 34.1998
CESS GDSC1 2.68 8.4182 0.7843 31.7345
MV4-11 GDSC1 2.7804 14.8422 -2.2723 39.429
NU-DUL-1 GDSC1 2.7851 13.3042 -1.5065 38.0588
BV-173 GDSC1 2.8414 6.5381 1.825 25.3722
MOLT-4 GDSC1 2.8713 6.4984 1.8732 24.9132
ARH-77 GDSC1 2.9232 7.1668 1.6143 26.2464
Farage GDSC1 2.9554 5.1764 2.5338 19.9712
ST486 GDSC1 3.0052 4.6321 2.7897 17.9025
HH [Human lymphoma] GDSC1 3.1124 6.6852 2.026 22.7125
RL GDSC1 3.1311 4.7028 2.9015 16.4346
Granta-519 GDSC1 3.1459 6.0386 2.3586 20.2539
RS4;11 GDSC1 3.2473 5.133 2.8593 16.1265
SU-DHL-6 GDSC1 3.2898 13.7509 -1.2781 35.6623
U266B1 GDSC1 3.3098 6.4074 2.35 19.529
MC116 GDSC1 3.4088 3.9512 3.3968 11.49
SU-DHL-5 GDSC1 3.4398 5.1272 3.0627 13.669
KCL-22 GDSC1 3.4512 9.5917 0.9304 27.454
EoL-1 GDSC1 3.5109 8.1071 1.7172 22.8539
BL-41 GDSC1 3.545 8.0743 1.7646 22.4072
SU-DHL-1 GDSC1 3.5868 4.171 3.5553 9.3919
Namalwa GDSC1 3.6385 5.3899 3.1487 12.066
CCRF-CEM GDSC1 3.6395 11.3648 0.2168 29.7674
Jiyoye GDSC1 3.6665 4.5399 3.5372 9.0662
EJM GDSC1 3.6806 14.167 -1.1448 33.9263
SUP-HD1 GDSC1 3.6852 6.2264 2.7981 14.517
SR GDSC1 3.7021 4.5809 3.5605 8.7108
P30/OHK GDSC1 3.7162 4.6837 3.5361 8.8119
CA46 GDSC1 3.7435 5.8841 3.0185 12.5796
BE-13 GDSC1 3.7739 5.0423 3.443 9.2105
OPM-2 GDSC1 3.7784 4.8391 3.537 8.4891
HC-1 GDSC1 3.7787 11.699 0.1714 29.3939
AMO1 GDSC1 3.7845 5.805 3.0957 11.8072
VAL GDSC1 3.7869 4.8133 3.5569 8.3007
SK-MM-2 GDSC1 3.7947 5.5496 3.2278 10.7486
Karpas-620 GDSC1 3.7957 4.428 3.7156 7.1132
Karpas-422 GDSC1 3.7958 4.2237 3.7712 6.7351
Ramos.2G6.4C10 GDSC1 3.8035 4.2434 3.7755 6.661
SU-DHL-16 GDSC1 3.821 4.301 3.7808 6.5244
Daudi GDSC1 3.8387 4.3748 3.7793 6.4341
GR-ST GDSC1 3.8428 5.1036 3.4843 8.5747
LP-1 GDSC1 3.8436 5.5155 3.2912 10.0441
HEL GDSC1 3.8496 4.3749 3.791 6.2927
Ku812 GDSC1 3.8516 5.0259 3.5287 8.1974
RPMI-8866 GDSC1 3.8797 4.5088 3.7779 6.2203
NK-92MI GDSC1 3.8856 7.8382 2.1882 18.1447
L-363 GDSC1 3.9074 4.5324 3.7986 5.9261
JVM-3 GDSC1 3.9117 7.4404 2.4089 16.4647
BALL-1 GDSC1 3.9203 4.6314 3.7726 6.0482
Sc-1 GDSC1 3.9462 4.6977 3.7714 5.9273
HDLM-2 GDSC1 3.9541 5.6402 3.3358 9.2197
L-540 GDSC1 3.9605 4.7368 3.7691 5.8738
Raji GDSC1 3.9745 4.6622 3.816 5.4573
TK [Human B-cell lymphoma] GDSC1 3.9781 6.8761 2.7481 13.6665
KMS-12-BM GDSC1 4.0111 4.742 3.8182 5.2634
HT GDSC1 4.0138 4.5355 3.9103 4.5679
L-428 GDSC1 4.0238 4.7196 3.8412 5.0305
KM-H2 GDSC1 4.0508 5.3593 3.5629 7.0462
DEL GDSC1 4.058 4.5555 3.9483 4.0672
MHH-PREB-1 GDSC1 4.1399 5.0023 3.8203 4.669
SCC-3 GDSC1 4.1853 4.9006 3.9121 3.7633
TUR GDSC1 4.2079 5.1734 3.7978 4.5664
BC-3 GDSC1 4.3433 5.4565 3.7724 4.2574
Karpas-299 GDSC1 4.3462 7.1024 2.9519 10.691
DB GDSC1 4.3721 5.8565 3.596 5.5455
Reh GDSC1 4.3828 6.213 3.4266 6.8429
SU-DHL-4 GDSC1 4.3886 5.3407 3.8669 3.3541
U-698-M GDSC1 4.4167 5.6081 3.7561 4.1312
ROS-50 GDSC1 4.4241 5.566 3.7829 3.8952
P32/ISH GDSC1 4.4354 8.7673 2.1931 15.9841
A4/Fukuda GDSC1 4.4512 11.2607 0.9597 23.3384
K-562 GDSC1 4.4571 6.4327 3.377 6.9761
RPMI-8226 GDSC1 4.592 7.0993 3.1514 8.2883
KOPN-8 GDSC1 4.6172 12.6428 0.4049 25.3548
WSU-DLCL2 GDSC1 4.6309 9.0579 2.2063 15.1954
CTV-1 GDSC1 4.7285 8.4234 2.5993 12.0415
JJN-3 GDSC1 4.8132 12.2798 0.7447 23.1283
RC-K8 GDSC1 5.0248 6.6453 3.6807 3.0064
DG-75 GDSC1 5.0927 7.9377 3.1092 7.0893
KMS-11 GDSC1 5.1461 7.5662 3.3246 5.3295
L-1236 GDSC1 5.3295 11.0036 1.7791 15.7163
P31/FUJ GDSC1 5.3685 7.0301 3.7085 2.1136
KY821 GDSC1 5.4765 8.5011 3.0984 6.1594
JVM-2 GDSC1 6.0609 9.9921 2.7718 7.0797
⏷ Show the Full List of 146 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC1 -1.9797 4.8881 -2.7178 65.7636
KYAE-1 GDSC1 3.1066 7.1153 1.8172 24.0989
KYSE-220 GDSC1 3.2189 14.3338 -1.6306 36.6966
ESO-51 GDSC1 3.5635 7.6125 2.0085 20.7431
OACM5.1 C GDSC1 3.637 7.1963 2.2805 18.5448
SK-GT-4 GDSC1 3.8028 7.2992 2.3813 17.1155
KYSE-50 GDSC1 4.0031 5.0503 3.6669 6.4495
FLO-1 GDSC1 4.3607 8.4685 2.2809 15.6422
TE-12 GDSC1 5.1648 19.0013 -2.3277 32.1852
HCE-4 GDSC1 5.1946 7.2783 3.4923 3.9743
ESO-26 GDSC1 5.8817 8.1395 3.5028 2.544
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 4.3251 8.3207 2.3252 15.4586
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-212 GDSC1 -5.6075 -0.7008 -5.6592 90.5081
SK-N-AS GDSC1 -4.08 7.3139 -5.8089 69.2355
NB69 GDSC1 -1.7958 3.2682 -2.0992 67.8875
TGW GDSC1 2.7535 9.6046 0.2817 33.3748
SK-N-SH GDSC1 3.2455 8.5156 1.272 26.631
NH-12 GDSC1 3.843 13.7002 -0.772 32.3283
LA-N-6 GDSC1 4.2544 10.0253 1.4137 21.6176
Kelly GDSC1 4.3962 5.9979 3.545 5.8639
SJNB-5 GDSC1 4.4495 10.4244 1.3763 21.1033
GI-ME-N GDSC1 4.4884 6.8294 3.204 8.2257
SK-N-BE(2)-M17 GDSC1 4.5968 9.2504 2.0828 16.1617
SK-N-DZ GDSC1 4.7154 8.7602 2.4216 13.3825
IMR-5 GDSC1 4.8747 8.1697 2.8371 9.7924
SJNB-7 GDSC1 4.9258 10.3854 1.7776 17.0244
KP-N-YS GDSC1 5.043 7.4294 3.3203 5.6336
NB(TU)1 GDSC1 5.2769 12.6804 0.9094 20.7933
SK-N-MC-IXC GDSC1 5.3268 15.1994 -0.3037 25.8993
KP-N-YN GDSC1 5.3434 8.0292 3.2348 5.494
SK-N-FI GDSC1 5.6283 14.4716 0.2904 22.616
SJNB-14 GDSC1 5.6312 7.1348 3.7988 1.1778
GOTO GDSC1 5.8901 7.9166 3.6021 1.9334
SJNB-17 GDSC1 5.9697 8.0317 3.5937 1.8692
SiMa GDSC1 5.9823 8.1735 3.5406 2.1592
CHP-134 GDSC1 6.0104 11.7003 1.9274 12.8161
SJNB-12 GDSC1 6.0378 10.8424 2.3569 9.9545
SJNB-10 GDSC1 6.0773 9.7442 2.8965 6.1894
SJNB-13 GDSC1 6.4272 8.3247 3.6864 0.9038
MHH-NB-11 GDSC1 6.7449 9.4044 3.4039 1.9143
SJNB-6 GDSC1 6.7926 17.557 -0.3666 22.1027
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 3.8034 4.6815 3.6292 7.6876
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 GDSC1 -5.2147 -3.7362 -5.2147 99.1837
BT-20 GDSC1 -0.3803 2.1775 -0.4206 52.3442
ZR-75-30 GDSC1 0.3052 5.1827 -0.3237 46.0256
HCC202 GDSC1 0.983 12.2731 -2.6912 46.9405
HCC1954 GDSC1 1.1988 4.6469 0.8196 36.6579
MDA-MB-453 GDSC1 1.3204 4.0793 1.1092 34.5841
EFM-19 GDSC1 2.4708 8.3375 0.6202 33.4903
JIMT-1 GDSC1 2.7151 6.5597 1.6883 24.1877
T-47D GDSC1 2.7819 9.1545 0.5269 29.7293
HCC70 GDSC1 2.8437 4.3858 2.6909 17.3858
HCC1599 GDSC1 2.9251 6.4106 1.9672 24.0316
UACC-893 GDSC1 3.3007 5.4207 2.7921 14.5934
HCC1187 GDSC1 3.3993 8.5497 1.3972 25.243
HCC1500 GDSC1 3.4874 4.947 2.6673 4.9759
CAL-85-1 GDSC1 3.5427 7.1719 2.2049 17.4936
MDA-MB-175-VII GDSC1 3.62 6.988 2.3666 16.1316
OCUB-M GDSC1 3.6628 4.8282 3.4211 9.9203
HCC2218 GDSC1 3.699 8.6115 1.6382 22.5228
BT-474 GDSC1 3.7037 6.3343 2.7633 14.6996
HCC1937 GDSC1 3.7088 6.5137 2.6809 13.6745
MDA-MB-157 GDSC1 3.7951 7.7704 2.1411 16.9488
MDA-MB-330 GDSC1 3.8434 10.8899 0.6311 27.2211
MDA-MB-468 GDSC1 3.9097 6.4171 2.9137 11.3207
UACC-812 GDSC1 3.9563 9.2468 1.5485 21.9963
MDA-MB-361 GDSC1 3.9818 4.9355 3.7001 6.2931
HCC1569 GDSC1 3.9849 5.4572 3.4538 8.1736
HDQ-P1 GDSC1 4.0041 10.8462 0.7913 23.7955
AU565 GDSC1 4.0152 10.0241 1.2113 21.6419
MFM-223 GDSC1 4.0246 4.5829 3.9019 4.5751
MDA-MB-231 GDSC1 4.1243 9.2876 1.6726 18.6716
EFM-192A GDSC1 4.1659 5.7395 3.4793 7.2328
Evsa-T GDSC1 4.2105 5.0154 3.8785 3.9231
CAL-120 GDSC1 4.2251 7.1338 2.8345 10.766
HCC1419 GDSC1 4.3684 9.0264 2.0083 15.7971
COLO 824 GDSC1 4.4479 5.9564 3.6072 5.1971
HCC38 GDSC1 4.4779 9.6516 1.7859 16.8089
CAL-148 GDSC1 4.5962 5.9961 3.7009 3.9895
YMB-1-E GDSC1 4.6705 6.2491 3.6312 4.3078
HCC1428 GDSC1 4.7522 7.4562 3.0973 7.3169
BT-549 GDSC1 4.7662 11.6839 1.0044 20.2248
CAL-51 GDSC1 4.8023 8.3642 2.6858 9.9983
MCF-7 GDSC1 4.8565 6.6615 3.5621 3.8462
MDA-MB-415 GDSC1 4.9894 7.2522 3.3689 4.8312
HCC2157 GDSC1 5.0271 6.7489 3.6337 3.3423
CAMA-1 GDSC1 5.0995 8.1563 3.0078 7.0028
HCC1806 GDSC1 5.1738 9.2921 2.5061 10.1643
MDA-MB-436 GDSC1 5.2341 7.675 3.331 4.516
Hs 578T GDSC1 5.5147 10.4245 2.1985 12.4365
BT-483 GDSC1 5.5255 13.2129 0.8353 20.3932
MRK-nu-1 GDSC1 6.0907 7.5991 3.8205 0.6289
HCC1395 GDSC1 6.662 8.642 3.6644 0.7222
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ONS-76 GDSC1 0.8456 9.6183 -1.5832 46.9737
D-566MG GDSC1 2.0382 3.5648 1.9881 28.8635
AM-38 GDSC1 2.3635 12.8957 -1.6895 40.0569
NMC-G1 GDSC1 2.3997 7.0448 1.1505 31.5219
MOG-G-UVW GDSC1 3.122 5.0257 2.7703 17.4141
D-423MG GDSC1 3.1399 8.5222 1.1705 25.2011
SF268 GDSC1 3.643 10.2986 0.7505 27.491
GI-1 GDSC1 3.6987 5.5851 3.1175 12.0241
8-MG-BA GDSC1 3.7254 4.2148 3.6967 7.6415
Onda 11 GDSC1 3.7608 8.1185 1.9378 20.3626
KS-1 [Human Krukenberg tumour] GDSC1 3.7735 12.2502 -0.108 30.4489
Daoy GDSC1 3.7873 9.8449 1.1031 25.166
DK-MG GDSC1 3.8518 12.8809 -0.3554 31.0019
M059J GDSC1 3.9053 4.6881 3.7332 6.4115
KINGS-1 GDSC1 3.949 6.1247 3.0935 11.1233
U-251MG GDSC1 3.9621 9.1686 1.5926 21.709
A-172 GDSC1 3.9936 5.7645 3.3116 9.2415
LN-405 GDSC1 3.9976 4.8391 3.7604 5.7624
KNS-42 GDSC1 3.9994 4.5734 3.8796 4.8658
PFSK-1 GDSC1 4.1085 5.7129 3.4414 7.7576
YKG-1 GDSC1 4.1206 5.6072 3.5046 7.2139
GaMG GDSC1 4.1318 7.3655 2.6389 13.887
H4 GDSC1 4.1443 5.0251 3.8132 4.7056
D-542MG GDSC1 4.1725 4.8932 3.9039 3.8809
D-263MG GDSC1 4.2162 4.9901 3.8961 3.7615
SF539 GDSC1 4.2374 5.2763 3.7726 4.6482
D-336MG GDSC1 4.2546 5.6712 3.5904 6.0182
Onda 10 GDSC1 4.2601 5.6183 3.6215 5.752
SF295 GDSC1 4.2964 5.3528 3.7851 4.3276
Hs 683 GDSC1 4.3289 6.4942 3.2416 7.5784
LN-18 GDSC1 4.3645 5.1691 3.9333 2.9141
KNS-81-FD GDSC1 4.4559 6.2503 3.467 6.272
SNB-75 GDSC1 4.4813 5.9933 3.6151 5.0237
Becker GDSC1 4.5235 5.8502 3.7186 4.0767
LNZTA3WT4 GDSC1 4.5632 5.8145 3.7659 3.5846
42-MG-BA GDSC1 4.5681 5.7233 3.8143 3.1949
CAS-1 GDSC1 4.5782 6.1982 3.5878 4.925
D-392MG GDSC1 4.5787 8.475 2.4553 13.608
U-87MG ATCC GDSC1 4.6357 6.0745 3.6914 3.9451
SW1088 GDSC1 4.637 5.9401 3.758 3.4278
SK-MG-1 GDSC1 4.7374 9.9751 1.8337 15.6984
SF126 GDSC1 4.8222 11.1067 1.3369 20.0064
D283 Med GDSC1 5.062 6.7784 3.642 3.1999
SW1783 GDSC1 5.1277 7.4467 3.3693 5.0442
T98G GDSC1 5.1677 6.6788 3.7514 2.2048
DBTRG-05MG GDSC1 5.2026 21.6659 -3.6275 34.5964
MOG-G-CCM GDSC1 5.2966 9.7888 2.3521 12.0262
D-247MG GDSC1 5.4498 7.8142 3.4022 4.0401
LN-229 GDSC1 5.6091 16.9557 -0.9569 27.309
GB-1 GDSC1 6.0075 21.2472 -2.7803 31.0275
YH-13 GDSC1 6.3036 13.335 1.3409 14.2255
KALS-1 GDSC1 6.9122 15.1661 0.8772 16.3749
U-118MG GDSC1 7.2189 8.9986 3.7492 0.2793
D-502MG GDSC1 7.3044 19.9731 -1.1787 23.6988
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 3.9593 6.2572 3.0377 11.5141
TGBC24TKB GDSC1 4.4332 7.8651 2.6422 12.7415
TGBC1TKB GDSC1 5.6878 10.37 2.3467 10.9448
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-280 GDSC1 1.4885 9.5059 -0.8918 42.7681
MFE-319 GDSC1 3.4702 7.0956 2.1741 17.9782
MFE-296 GDSC1 5.084 7.5586 3.2863 5.7797
RL95-2 GDSC1 5.2619 6.8062 3.748 2.0484
EN GDSC1 5.486 8.513 3.099 5.4811
KLE GDSC1 5.6417 9.0679 2.9381 6.9079
ESS-1 GDSC1 6.4237 12.2201 1.9571 11.5621
AN3-CA GDSC1 6.6738 13.6872 1.4246 14.0774
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-195 GDSC1 0.9253 2.0425 0.924 42.465
769-P GDSC1 1.3343 5.6703 0.6146 36.6605
KTCTL-1M GDSC1 2.483 5.7273 1.8117 27.3728
786-O GDSC1 3.2381 6.493 2.2395 18.4978
LB1047-RCC GDSC1 3.637 7.898 1.9352 18.8479
KTCTL-140 GDSC1 3.7305 8.3742 1.784 21.4843
ACHN GDSC1 3.9708 6.1263 3.1127 9.715
KTCTL-21 GDSC1 4.0035 8.4484 1.9877 19.0347
RCC10RGB GDSC1 4.0504 6.3586 2.3867 5.4639
Caki-1 GDSC1 4.2523 6.7201 3.0643 9.0729
NCC021 GDSC1 4.4144 5.7911 3.6629 4.8721
VMRC-RCZ GDSC1 4.519 7.7826 2.753 10.3857
A-704 GDSC1 4.5579 6.2676 3.538 5.3784
HA7-RCC GDSC1 4.6541 8.6318 2.4372 12.1096
UO-31 GDSC1 4.6832 9.3479 2.1033 14.1927
VMRC-RCW GDSC1 4.7231 7.1522 3.2256 7.2906
KTCTL-13 GDSC1 4.8126 7.186 3.2754 6.6322
KMRC-1 GDSC1 4.8392 6.9047 3.4321 5.3502
KTCTL-26A GDSC1 4.852 8.558 2.6278 11.4262
SW156 GDSC1 4.8527 6.9906 3.3999 4.9601
BFTC-909 GDSC1 4.9002 8.0448 2.9177 9.1038
A-498 GDSC1 5.1011 7.4401 3.3546 5.2222
KMRC-20 GDSC1 5.1751 7.7281 3.2667 5.0767
SN12C GDSC1 5.5182 8.9697 2.9035 6.6859
BB65-RCC GDSC1 5.5724 8.6779 3.077 5.4364
CAL-54 GDSC1 5.6338 13.1585 0.9436 19.5201
OS-RC-2 GDSC1 6.0777 10.4768 2.5558 7.6626
SW13 GDSC1 6.506 8.1459 3.7848 0.4347
TK-10 GDSC1 6.8601 13.2881 1.7366 10.8072
RXF 393L GDSC1 7.1049 9.4537 3.5421 0.8513
LB2241-RCC GDSC1 7.1513 8.9572 3.7392 0.2887
LB996-RCC GDSC1 7.3877 9.6771 3.5726 0.5973
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1463 GDSC1 -1.4971 18.7652 -8.18 54.8404
COLO205 GDSC1 -0.5282 7.2373 -1.9777 55.4251
HT-29 GDSC1 -0.2354 9.5497 -2.6475 52.9309
SW837 GDSC1 -0.058 16.8184 -5.8684 51.2092
SW626 GDSC1 0.3174 5.3473 -0.3659 50.0398
RCM-1 [Human ESC] GDSC1 0.428 8.5627 -1.5335 49.346
NCI-H747 GDSC1 0.6079 3.868 0.3831 46.8793
SNU-81 GDSC1 1.3485 15.001 -3.6607 46.0146
SNU-407 GDSC1 1.7826 4.9853 1.3449 34.2566
HCT 116 GDSC1 2.5321 12.3123 -1.248 38.553
LS180 GDSC1 2.6185 11.7036 -0.8695 37.3636
T84 GDSC1 2.8364 10.8729 -0.2612 34.7932
SNU-61 GDSC1 2.9122 11.0702 -0.2888 34.5458
HCT 15 GDSC1 3.6334 7.0114 2.3677 17.9372
LoVo GDSC1 3.8677 6.0151 3.0723 11.6284
SNU-C5 GDSC1 3.8751 8.9187 1.6413 21.7679
MDST8 GDSC1 4.0987 9.5205 1.5343 21.5147
SW1417 GDSC1 4.1169 9.5282 1.5461 19.4344
SNU-175 GDSC1 4.1872 8.3034 2.2178 16.7394
SW620 GDSC1 4.2474 16.6716 -1.9151 33.9032
GP5d GDSC1 4.285 11.8727 0.5157 26.0511
CaR-1 GDSC1 4.2888 6.5724 3.1689 9.2078
C2BBe1 GDSC1 4.4591 10.7558 1.2186 21.9472
CCK-81 GDSC1 4.5403 8.1254 2.599 12.6855
LS123 GDSC1 4.5418 20.7744 -3.7217 36.4013
SW948 GDSC1 4.5594 7.3268 3.0125 9.4759
HT-55 GDSC1 4.7929 6.1543 3.7623 2.9714
RKO GDSC1 4.8467 10.7224 1.5478 18.6993
COLO 320HSR GDSC1 4.9237 10.728 1.6056 18.0919
HCC2998 GDSC1 4.9247 7.3827 3.2601 6.4206
LS513 GDSC1 5.1066 7.8822 3.1457 6.7754
HT115 GDSC1 5.1125 7.739 3.2189 6.2088
SW48 GDSC1 5.1134 8.9507 2.6295 10.5987
SNU-1040 GDSC1 5.2959 11.3096 1.6029 16.9002
SNU-C1 GDSC1 5.3619 8.3627 3.0887 6.5191
LS1034 GDSC1 5.5783 7.1908 3.7498 1.5225
LS411N GDSC1 5.7815 11.4885 1.8702 13.8071
KM12 GDSC1 5.8396 12.4652 1.4354 16.2509
NCI-H716 GDSC1 6.0546 8.2659 3.5382 2.0683
CW-2 GDSC1 6.1525 8.1225 3.6441 1.3676
COLO 678 GDSC1 6.4141 10.8938 2.5727 7.6257
SW1116 GDSC1 6.4826 8.006 3.8261 0.3758
SNU-C2B GDSC1 7.4448 9.9818 3.4836 0.9336
CL-11 GDSC1 7.613 14.8747 1.4709 11.6537
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 0.1472 5.8023 -0.7096 51.4215
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-387 GDSC1 1.014 6.2458 0.0509 44.0894
SNU-423 GDSC1 2.3077 8.3264 0.4662 34.9374
JHH-1 GDSC1 3.2438 8.9896 1.0383 25.4495
SNU-449 GDSC1 3.8255 5.64 3.2143 10.7156
SNU-398 GDSC1 3.9577 8.0096 2.1664 18.0028
Huh-7 GDSC1 4.2587 9.1724 1.8438 18.9823
Hep 3B2.1-7 GDSC1 5.1372 6.9914 3.59 3.4011
JHH-2 GDSC1 5.4596 8.5425 3.0678 5.7437
JHH-6 GDSC1 5.8585 6.7108 4.0494 0.0915
HuH-1 GDSC1 5.9125 7.179 3.9044 0.4424
SK-HEP-1 GDSC1 6.249 7.4431 3.9375 0.1931
Hep-G2/C3A GDSC1 6.4339 7.8779 3.8533 0.324
JHH-4 GDSC1 6.4763 8.3985 3.679 0.798
JHH-7 GDSC1 6.5456 8.1702 3.7914 0.3978
HLE GDSC1 7.253 9.0142 3.756 0.2279
SNU-475 GDSC1 8.8377 18.6525 0.4791 14.0376
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 172 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1792 GDSC1 -0.2503 0.9752 -0.2506 50.9954
NCI-H2405 GDSC1 -0.1383 17.0041 -6.0343 51.4428
NCI-H1304 GDSC1 -0.1354 4.0278 -0.4654 54.473
NCI-H1755 GDSC1 0.1635 6.3355 -0.8901 51.212
NCI-H196 GDSC1 0.5732 4.4873 0.1845 43.0624
CAL-12T GDSC1 1.0977 6.9172 -0.1339 43.8377
NCI-H1437 GDSC1 1.2482 7.0886 -0.0492 42.6731
NCI-H727 GDSC1 1.3747 21.795 -6.9778 47.2138
COR-L105 GDSC1 1.3834 8.2553 -0.4228 42.5583
NCI-H1781 GDSC1 1.4408 16.8137 -4.462 46.115
NCI-H1944 GDSC1 1.4627 6.5316 0.4087 40.124
NCI-H596 GDSC1 1.5755 8.7892 -0.4732 41.5552
NCI-H2795 GDSC1 1.5828 4.9399 1.1436 32.8888
NCI-H23 GDSC1 1.7458 5.6617 1.0577 32.3946
Lu-65 GDSC1 1.9151 7.9533 0.2498 37.8287
LXF 289 GDSC1 2.0513 3.8104 1.9625 25.8321
NCI-H1648 GDSC1 2.1072 7.8345 0.4964 35.9216
NCI-H2085 GDSC1 2.1448 8.6062 0.1751 36.7952
SK-MES-1 GDSC1 2.1768 6.6345 1.1065 32.9983
NCI-H292 GDSC1 2.2308 11.2491 -1.0084 39.3662
NCI-H1568 GDSC1 2.2585 4.7945 1.9254 24.9732
NCI-H2227 GDSC1 2.3475 6.5068 1.3377 30.8627
ABC-1 GDSC1 2.3521 6.7603 1.2303 31.3899
NCI-H522 GDSC1 2.5978 3.8145 2.5507 21.8522
A-549 GDSC1 2.6977 4.4416 2.5153 19.1906
NCI-H3122 GDSC1 2.7708 7.853 1.1414 29.604
Lu-139 GDSC1 2.795 6.1799 1.9397 24.8786
HARA [Human squamous cell lung carcinoma] GDSC1 2.8036 5.5967 2.2016 23.0866
NCI-H1770 GDSC1 2.849 6.8072 1.7089 26.0531
NCI-H650 GDSC1 2.8565 7.7485 1.274 28.4899
EPLC-272H GDSC1 2.913 11.1485 -0.3265 34.6554
NCI-H1563 GDSC1 2.9479 4.9809 2.6022 17.4295
NCI-H2373 GDSC1 2.9642 10.7708 -0.0938 33.7066
PaCa-3 GDSC1 2.9709 5.6274 2.3624 21.1031
NCI-H2347 GDSC1 2.9714 6.7008 1.8797 24.3658
EBC-1 GDSC1 3.0663 5.8702 2.3538 18.4916
COR-L321 GDSC1 3.1054 5.9159 2.3731 20.3506
COR-L303 GDSC1 3.2657 5.3152 2.8017 16.4527
NCI-H358 GDSC1 3.3083 11.8629 -0.3233 32.9961
NCI-H1048 GDSC1 3.3559 4.6883 3.1491 13.4776
NCI-H1703 GDSC1 3.3596 7.1384 2.0488 19.2223
LCLC-97TM1 GDSC1 3.4482 6.134 2.6141 16.9628
NCI-H1650 GDSC1 3.459 5.4349 2.9475 14.4276
NCI-H2141 GDSC1 3.4898 12.1805 -0.3207 32.2657
NCI-H2030 GDSC1 3.5037 10.2797 0.6364 28.5889
NCI-H810 GDSC1 3.5356 10.5426 0.5342 28.8989
COLO 668 GDSC1 3.5406 14.0831 -1.2241 34.6229
NCI-H1869 GDSC1 3.5458 10.9663 0.3327 29.69
HCC15 GDSC1 3.5559 6.7772 2.4093 17.9773
A-427 GDSC1 3.5941 8.7341 1.4833 21.6993
SHP-77 GDSC1 3.6052 9.3873 1.1696 25.5807
NCI-H2731 GDSC1 3.6519 12.5958 -0.3859 31.8502
NCI-H2444 GDSC1 3.6791 8.7768 1.5385 21.0623
SK-LU-1 GDSC1 3.6902 5.8418 2.9876 13.0526
Lu-99A GDSC1 3.6954 6.4703 2.6895 13.6676
LC-2/ad GDSC1 3.7228 5.1392 3.3477 10.1699
NCI-H226 GDSC1 3.7844 12.4978 -0.2222 30.805
NCI-H290 GDSC1 3.8133 12.6396 -0.268 30.8524
SBC-3 GDSC1 3.8231 4.7484 3.6221 7.6396
SW1271 GDSC1 3.8359 9.5878 1.2737 21.9519
NCI-H64 GDSC1 3.8649 4.2354 3.8439 5.848
NCI-H1876 GDSC1 3.8656 4.5614 3.7429 6.5447
NCI-H847 GDSC1 3.8835 4.4427 3.8058 6.0033
NCI-H661 GDSC1 3.9062 6.3203 2.9581 12.3486
NCI-H1694 GDSC1 3.9078 5.1348 3.5341 7.8964
HCC44 GDSC1 3.9156 7.7505 2.2583 17.5296
NCI-H520 GDSC1 3.9557 4.6043 3.821 5.515
NCI-H647 GDSC1 3.959 8.3622 1.9919 17.3052
Ms-1 GDSC1 3.9954 4.7111 3.8161 5.3547
NCI-H2170 GDSC1 4.0032 6.7743 2.821 13.009
NCI-H1581 GDSC1 4.0084 5.3581 3.5239 7.5294
RERF-LC-MS GDSC1 4.0495 8.1379 2.1824 17.5238
HCC827 GDSC1 4.0771 6.6182 2.9639 11.6137
NCI-H1993 GDSC1 4.0916 12.7295 -0.0753 29.1454
RERF-LC-Sq1 GDSC1 4.0989 7.4718 2.5575 14.6247
COR-L23 GDSC1 4.1087 8.4097 2.0977 17.8755
NCI-H1155 GDSC1 4.1236 6.5909 3.0182 11.0103
LCLC-103H GDSC1 4.1297 4.7283 3.9425 3.7701
NCI-H1573 GDSC1 4.1336 6.8274 2.909 11.8184
COR-L311 GDSC1 4.135 6.0301 3.3075 8.7033
EMC-BAC-2 GDSC1 4.1609 8.0707 2.3117 16.1771
IST-SL2 GDSC1 4.2127 7.5115 2.6352 13.6057
NCI-H2228 GDSC1 4.2177 6.4813 3.1542 8.5587
NCI-H2342 GDSC1 4.2204 6.1711 3.3114 8.3436
ChaGo-K-1 GDSC1 4.231 6.2344 3.2889 7.5678
NCI-H2122 GDSC1 4.2321 8.8999 1.9577 18.3404
NCI-H2171 GDSC1 4.2638 6.7651 3.0516 10.2178
SBC-5 GDSC1 4.2751 7.3055 2.7909 12.1914
UMC-11 GDSC1 4.2852 5.5876 3.6582 4.7909
LB647-SCLC GDSC1 4.3023 7.5135 2.7098 12.7081
IA-LM GDSC1 4.3062 8.0425 2.4485 14.6389
HCC78 GDSC1 4.3349 7.2741 2.8566 10.2518
NCI-H1836 GDSC1 4.3421 5.528 3.7356 4.5516
NCI-H441 GDSC1 4.3494 8.0912 2.4601 14.3939
BEN GDSC1 4.3907 5.5536 3.7624 4.1697
NCI-H1915 GDSC1 4.4006 10.7866 1.1549 22.5064
SW1573 GDSC1 4.4614 11.3164 0.9402 23.3993
NCI-H1623 GDSC1 4.463 6.2372 3.4792 6.1521
LOU-NH91 GDSC1 4.482 6.1448 3.5403 5.6087
HCC33 GDSC1 4.4983 6.0093 3.6204 4.9262
NCI-H1838 GDSC1 4.5287 6.2793 3.5098 5.6941
PC-14 GDSC1 4.5853 6.5507 3.4187 6.2238
LK-2 GDSC1 4.5932 7.7881 2.8094 10.9209
NCI-H69 GDSC1 4.5992 7.1093 3.152 8.2601
Calu-3 GDSC1 4.6003 12.6477 0.3887 25.4836
NCI-H211 GDSC1 4.6141 7.4789 2.9798 9.5449
NCI-H524 GDSC1 4.6254 5.977 3.7317 3.6642
LC-1/sq GDSC1 4.645 9.8568 1.8189 16.0761
SBC-1 GDSC1 4.7802 8.795 2.4549 12.925
NCI-H345 GDSC1 4.7825 5.9134 3.8694 2.2048
NCI-H1793 GDSC1 4.7971 8.0587 2.8332 10.0671
NCI-H2869 GDSC1 4.8147 11.2146 1.2771 20.3667
NCI-H322M GDSC1 4.8438 12.6142 0.6023 23.6963
NCI-H1355 GDSC1 4.8809 12.0946 0.891 22.1804
NCI-H187 GDSC1 4.8989 7.0988 3.3799 5.5794
IST-SL1 GDSC1 4.904 6.9815 3.4404 5.1045
DMS 53 GDSC1 4.9045 6.6697 3.5909 3.9653
NCI-H1436 GDSC1 4.9244 7.3044 3.2981 6.1315
NCI-H2135 GDSC1 4.9363 7.5354 3.1939 6.8926
EMC-BAC-1 GDSC1 4.9553 7.9576 3.0011 8.3042
NCI-H1092 GDSC1 4.9623 11.8653 1.0698 20.9888
NCI-H748 GDSC1 5.0222 7.0069 3.5086 4.2765
NCI-H209 GDSC1 5.0341 6.9901 3.5245 4.1285
DMS 114 GDSC1 5.049 10.6401 1.7464 16.8125
RERF-LC-KJ GDSC1 5.0566 16.4231 -1.1278 29.4273
NCI-H1688 GDSC1 5.0765 8.2896 2.9264 7.6132
Lu-134-A GDSC1 5.0945 7.7383 3.2068 6.3489
NCI-H1975 GDSC1 5.1001 8.5306 2.8256 9.1932
NCI-H2196 GDSC1 5.1056 7.8365 3.1671 6.6172
NCI-H720 GDSC1 5.1076 7.4637 3.3477 5.2565
NCI-H2369 GDSC1 5.113 7.1551 3.4979 4.1294
NCI-H82 GDSC1 5.1739 7.5263 3.362 4.9807
NCI-H1693 GDSC1 5.1799 11.4225 1.4588 18.1198
NCI-H510A GDSC1 5.2342 7.1671 3.5686 3.3364
NCI-H841 GDSC1 5.2445 8.1927 3.0909 6.8106
NCI-H1734 GDSC1 5.2729 8.378 3.0213 7.2508
NCI-H2023 GDSC1 5.3016 8.2118 3.1204 6.441
COR-L95 GDSC1 5.5674 7.5553 3.5873 2.5451
Calu-6 GDSC1 5.5871 9.9368 2.4861 10.2589
NCI-H2081 GDSC1 5.595 11.9236 1.5228 16.4599
CPC-N GDSC1 5.6715 7.8463 3.5167 2.817
NCI-H2029 GDSC1 5.6956 11.7379 1.6871 15.1836
NCI-H2087 GDSC1 5.7057 12.3946 1.3727 16.9963
NCI-H2461 GDSC1 5.7787 9.035 3.0405 5.8573
DMS 79 GDSC1 5.8009 12.2078 1.5333 15.7948
NCI-H2172 GDSC1 5.8316 7.4713 3.7569 1.1586
NCI-H1435 GDSC1 5.8415 8.164 3.4707 2.8138
NCI-H526 GDSC1 5.9014 12.441 1.4915 15.7513
HOP-92 GDSC1 5.9844 10.3508 2.5549 7.8718
NCI-H838 GDSC1 6.1405 10.9959 2.3516 8.7862
NCI-H2591 GDSC1 6.1663 10.9788 2.3765 9.5041
NCI-H460 GDSC1 6.2173 7.5833 3.8764 0.3212
COR-L88 GDSC1 6.2317 8.1917 3.6527 1.239
NCI-H2818 GDSC1 6.2347 9.8797 2.9289 5.0499
NCI-H3255 GDSC1 6.2403 11.7692 2.0501 10.3782
DMS 273 GDSC1 6.2566 9.5742 3.079 4.1143
NCI-H2804 GDSC1 6.323 15.1919 0.4509 19.9341
Lu-165 GDSC1 6.3389 7.5058 3.9479 0.1472
NCI-H446 GDSC1 6.3773 8.3389 3.6596 1.0637
NCI-H2009 GDSC1 6.3794 11.5849 2.2285 9.9548
HOP-62 GDSC1 6.384 8.4337 3.6255 1.213
NCI-H2110 GDSC1 6.4081 13.6678 1.2527 14.4389
NCI-H2595 GDSC1 6.4336 9.9125 3.0285 4.5954
NCI-H1651 GDSC1 6.5713 13.7791 1.3112 14.9642
NCI-H1666 GDSC1 6.6175 13.5705 1.4425 14.118
NCI-H2803 GDSC1 6.6812 8.4681 3.7362 0.5439
NCI-H2291 GDSC1 6.7663 8.7546 3.6648 0.7348
EKVX GDSC1 6.8003 12.6529 1.9962 10.4241
NCI-H513 GDSC1 6.9785 8.5659 3.8121 0.2256
Lu-135 GDSC1 7.0669 8.7281 3.7879 0.2471
NCI-H1299 GDSC1 7.395 23.1952 -2.6922 27.6736
NCI-H2722 GDSC1 7.4497 18.7778 -0.4945 20.9975
⏷ Show the Full List of 172 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 4.1242 7.0748 2.7774 12.866
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-450 GDSC1 0.6835 6.0898 -0.2406 46.9693
TE-15 GDSC1 0.7507 14.2648 -3.8682 48.3165
TE-6 GDSC1 3.2942 9.4393 0.8633 28.4656
KYSE-180 GDSC1 4.1473 5.4476 3.6077 6.2992
COLO 680N GDSC1 4.1643 6.1577 3.2696 8.8865
OE21 GDSC1 4.4778 5.7625 3.727 4.1568
T.T GDSC1 4.7456 6.3051 3.6574 3.8909
KYSE-140 GDSC1 4.7654 7.4844 3.0933 8.1806
OE33 GDSC1 4.7744 11.7798 0.963 22.1793
KYSE-520 GDSC1 4.8425 9.7093 2.0488 15.5438
KYSE-150 GDSC1 5.0237 6.5544 3.7222 2.7105
TE-10 GDSC1 5.1943 12.6378 0.8667 21.2714
KYSE-510 GDSC1 5.2682 6.625 3.8306 1.5095
TE-4 GDSC1 5.3047 8.5144 2.9774 7.4897
TE-9 GDSC1 5.3057 8.0452 3.2025 5.8255
KYSE-270 GDSC1 5.351 8.2731 3.1241 6.2867
EC-GI-10 GDSC1 5.6083 7.2304 3.7483 1.4888
KYSE-70 GDSC1 5.6248 7.7925 3.5145 2.9172
TE-11 GDSC1 5.633 8.2372 3.3189 4.2287
TE-8 GDSC1 5.7722 9.8235 2.6656 8.5132
TE-5 GDSC1 5.7889 9.7778 2.6984 8.2414
OE19 GDSC1 6.0146 7.2848 3.9059 0.3767
KYSE-410 GDSC1 6.5093 14.6518 0.8469 17.5527
TE-1 GDSC1 6.8474 17.6482 -0.3717 21.9852
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A2780 GDSC1 0.3115 6.0763 -0.6337 50.0836
Caov-4 GDSC1 0.6999 7.8247 -0.9328 47.4088
OV-90 GDSC1 1.4275 10.0671 -1.2144 43.5533
OAW42 GDSC1 1.818 5.2682 1.2829 34.3432
Kuramochi GDSC1 1.9031 7.3196 0.524 36.998
TOV-112D GDSC1 2.8352 6.5429 1.8167 22.8845
OVISE GDSC1 3.1276 9.429 0.7156 29.8905
OVCAR-8 GDSC1 3.6747 6.4413 2.6841 15.4234
FU-OV-1 GDSC1 3.7032 15.1133 -1.5976 34.9402
Caov-3 GDSC1 3.8042 4.3305 3.7546 6.7976
RMG-I GDSC1 4.0083 30.5102 -9.0345 42.4853
JHOS-2 GDSC1 4.1357 4.873 3.8792 4.2304
SK-OV-3 GDSC1 4.1651 7.157 2.7716 12.7531
OVKATE GDSC1 4.2603 11.724 0.5694 25.9025
OC 314 GDSC1 4.2832 8.8786 2.0112 16.0615
TYK-nu GDSC1 4.4411 6.9747 3.0935 9.2521
OVK18 GDSC1 4.4566 5.3695 3.9057 2.8261
TOV-21G GDSC1 4.5978 6.0877 3.6571 4.3247
IGROV-1 GDSC1 4.6006 14.1113 -0.3426 28.3368
OVCAR-4 GDSC1 4.6502 11.738 0.8837 23.01
EFO-27 GDSC1 4.7911 10.8944 1.4181 19.65
DOV13 GDSC1 5.1401 7.6281 3.2909 5.5961
OVTOKO GDSC1 5.186 8.4473 2.9275 8.1872
OAW28 GDSC1 5.2507 15.7148 -0.6202 27.2463
ES-2 GDSC1 5.3408 14.3254 0.1419 24.114
EFO-21 GDSC1 5.7854 8.3891 3.3397 3.7764
OV56 GDSC1 6.026 7.0195 4.0033 0.129
OVCAR-3 GDSC1 6.0335 10.1007 2.704 7.6087
OVCAR-5 GDSC1 6.0873 17.6842 -0.9511 25.9823
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuP-T4 GDSC1 1.2626 4.7032 0.8718 36.0402
SUIT-2 GDSC1 1.4342 6.9311 0.211 37.4998
Panc 02.03 GDSC1 1.7145 8.9073 -0.3898 37.7796
HPAF-II GDSC1 2.1365 7.6859 0.5939 32.4118
KP-4 GDSC1 2.2845 4.8465 1.9358 24.7797
PaTu 8902 GDSC1 2.6058 6.173 1.7491 24.3343
MZ-PC-1 GDSC1 2.7407 5.9114 2.0019 22.1821
KP-1N GDSC1 2.7621 4.9583 2.0187 12.9086
KP-2 GDSC1 2.8985 7.4981 1.4336 24.819
Panc 10.05 GDSC1 3.1327 6.1022 2.3163 18.4466
PSN1 GDSC1 3.2578 29.5162 -9.1726 43.9446
QGP-1 GDSC1 3.4197 19.4508 -4.0069 39.7858
SU.86.86 GDSC1 3.5507 6.3048 2.6321 14.6227
PaTu 8988t GDSC1 3.5655 6.923 2.3474 16.4701
HPAC GDSC1 3.6674 8.4156 1.7069 20.1232
Capan-1 GDSC1 3.6689 8.5474 1.643 22.6216
HuP-T3 GDSC1 3.7446 5.2922 3.2995 9.3069
DAN-G GDSC1 3.8697 5.9246 3.1183 10.0528
Panc 03.27 GDSC1 4.1416 6.4672 3.0956 10.3368
KP-3 GDSC1 4.153 10.9363 0.8729 24.8801
Panc 08.13 GDSC1 4.1542 11.4355 0.6244 24.0554
MIA PaCa-2 GDSC1 4.2176 6.4138 3.1879 9.3245
AsPC-1 GDSC1 4.5615 10.0455 1.6573 17.3039
BxPC-3 GDSC1 4.6454 8.2335 2.6288 10.8481
Panc 04.03 GDSC1 4.859 6.3077 3.733 2.6959
PL4 GDSC1 5.0151 10.3051 1.8866 14.5428
CFPAC-1 GDSC1 5.2608 9.1224 2.652 8.9728
SW1990 GDSC1 6.1362 10.4144 2.6223 7.1259
Capan-2 GDSC1 6.426 8.4157 3.6509 1.0575
YAPC GDSC1 6.7713 11.9676 2.2963 7.8027
Hs 766T GDSC1 7.0944 13.0458 1.997 8.8799
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 GDSC1 5.6725 8.0437 3.4296 3.3914
MPP 89 GDSC1 5.6993 8.7709 3.1137 5.5225
MSTO-211H GDSC1 6.0117 9.6274 2.9103 6.2396
NCI-H28 GDSC1 6.4691 8.631 3.586 1.3138
IST-Mes1 GDSC1 6.9075 13.1359 1.8383 11.1281
NCI-H2052 GDSC1 6.9601 8.5415 3.8139 0.2273
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1 1.6321 8.9152 -0.4752 41.2465
22Rv1 GDSC1 4.4073 9.8531 1.6271 19.7814
PC-3 GDSC1 4.8544 9.081 2.3703 13.2856
LNCaP clone FGC GDSC1 5.0417 6.8212 3.6091 3.4864
DU145 GDSC1 7.011 8.7387 3.7642 0.3163
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 5.5963 7.7605 3.5127 2.9825
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-mel GDSC1 -4.6628 4.398 -5.5042 75.5852
WM35 GDSC1 -2.1708 24.4369 -11.5523 55.0824
SH-4 GDSC1 -1.3775 9.3717 -3.7492 58.1611
A-375 GDSC1 -0.2583 13.6681 -4.5588 52.2142
451Lu GDSC1 0.2155 8.5641 -1.7527 50.6417
LB2518-MEL GDSC1 0.5133 7.0952 -0.8204 48.6047
SK-MEL-30 GDSC1 0.5252 11.9109 -2.9651 49.0653
MZ-MEL-7 GDSC1 0.8745 15.6272 -4.4098 48.0024
MMAc-SF GDSC1 1.0165 7.0167 -0.2604 44.5959
CP50-MEL-B GDSC1 1.0935 14.3707 -3.5941 46.9235
WT2-iPS GDSC1 1.4538 7.9837 -0.2295 41.7614
SK-MEL-1 GDSC1 1.564 14.1889 -3.0637 44.822
UACC-257 GDSC1 2.1335 9.9457 -0.4717 38.6366
A-431 GDSC1 2.1339 8.8525 0.0485 37.2403
Mel Ho GDSC1 2.3994 20.3525 -5.347 43.799
SK-MEL-24 GDSC1 2.5388 8.975 0.3822 34.0533
UACC-62 GDSC1 2.7517 10.6068 -0.2089 35.0122
Mel JuSo GDSC1 3.1772 12.0544 -0.5353 34.1664
MZ-MEL-2 GDSC1 3.1778 21.5275 -5.252 41.687
CHL-1 GDSC1 3.2115 8.1752 1.4065 26.0507
COLO 792 GDSC1 3.2957 7.4091 1.8575 20.6723
WM115 GDSC1 3.3032 9.4935 0.8448 28.5122
IPC-298 GDSC1 3.3153 10.6893 0.2648 30.9185
IGR-37 GDSC1 3.3225 10.7366 0.2479 30.953
A-388 GDSC1 3.5342 8.6081 1.4915 24.1057
M14 GDSC1 3.5586 6.7034 2.4476 17.6867
WM1552C GDSC1 3.6865 10.9855 0.4468 28.6499
SK-MEL-5 GDSC1 3.7863 9.4743 1.2868 22.0634
RPMI-7951 GDSC1 3.8073 12.9133 -0.4098 31.3445
LOX-IMVI GDSC1 3.8877 4.6315 3.7384 6.4633
DJM-1 GDSC1 3.9516 8.9516 1.6917 21.1472
RVH-421 GDSC1 3.9981 18.249 -2.9133 36.5885
GAK GDSC1 4.0971 9.9491 1.3189 22.7606
COLO 829 GDSC1 4.134 8.4666 2.0909 17.8232
IGR-1 GDSC1 4.2091 7.869 2.4535 14.9673
A2058 GDSC1 4.2614 6.5728 3.1457 8.4724
WM278 GDSC1 4.4188 14.3808 -0.627 29.8965
SK-MEL-2 GDSC1 4.4918 9.3608 1.9427 17.4728
IST-MEL1 GDSC1 4.54 10.194 1.5656 19.6681
SK-MEL-3 GDSC1 4.5722 21.6264 -4.1226 35.5748
LB373-MEL-D GDSC1 4.6529 12.1286 0.6908 23.9361
Hs 940.T GDSC1 4.9116 8.7346 2.5857 11.545
COLO 800 GDSC1 4.9402 7.3254 3.2991 6.0795
SK-MEL-28 GDSC1 5.0282 12.617 0.7473 22.3974
HT-144 GDSC1 5.1286 10.5351 1.8594 15.8425
CP66-MEL GDSC1 5.2476 22.8262 -4.1706 35.3537
VMRC-MELG GDSC1 5.3687 7.1184 3.6696 2.3684
COLO 783 GDSC1 5.4675 12.9717 0.9107 20.192
A101D GDSC1 5.5143 13.6254 0.6227 21.4568
COLO 679 GDSC1 5.5396 8.0621 3.3429 4.2616
HMV-II GDSC1 5.9284 24.2436 -4.3338 34.0648
G-361 GDSC1 6.8798 25.6731 -4.3041 32.0027
MeWo GDSC1 7.7929 16.2086 0.9623 13.9099
WM793 GDSC1 7.8779 25.9907 -3.7106 28.9025
Hs 938.T GDSC1 9.6874 24.6727 -1.8043 19.7673
EquiPSC Line K2 GDSC1 0.9506 10.7396 -1.9981 46.6961
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 1.6741 5.7073 0.9636 36.7556
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RKN GDSC1 -3.3917 6.1074 -4.6436 69.1112
Rh18 GDSC1 0.5188 68.1863 -30.8324 49.8404
SK-LMS-1 GDSC1 2.0416 5.4802 1.4431 32.1008
EW-8 GDSC1 3.0918 6.6223 2.0352 22.752
G-402 GDSC1 3.9853 9.1938 1.6001 19.5852
TE 441.T GDSC1 3.99 5.1167 3.6227 6.8474
SW982 GDSC1 4.2808 6.2813 3.3077 8.147
G-401 GDSC1 4.3321 9.5084 1.7372 17.5806
Rh41 GDSC1 4.6166 5.8157 3.8041 3.1321
VA-ES-BJ GDSC1 4.6559 7.5522 2.9759 9.4365
MES-SA GDSC1 4.7195 9.3946 2.1088 15.5577
RD GDSC1 4.9524 9.221 2.3759 12.9261
HT-1080 GDSC1 5.0402 8.8652 2.6176 10.9087
MFH-ino GDSC1 5.1267 10.8012 1.7261 16.6869
SK-UT-1 GDSC1 5.1751 6.854 3.6765 2.7048
SW872 GDSC1 5.2465 7.8076 3.2763 5.4304
Hs 633.T GDSC1 5.2502 13.06 0.7003 21.9074
A-204 GDSC1 5.3741 13.0537 0.7989 21.0393
SW684 GDSC1 5.3878 6.8558 3.7943 1.5425
GCT GDSC1 5.9222 7.5868 3.7523 1.0813
STS-0421 GDSC1 6.0576 8.8239 3.2999 3.5289
KYM-1 GDSC1 6.4217 7.9595 3.8196 0.4251
Rh30 GDSC1 6.6733 8.3402 3.7792 0.418
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AGS GDSC1 1.3002 5.0875 0.7874 40.0471
IM95 GDSC1 1.4206 7.2114 0.0767 37.9938
SNU-1 GDSC1 2.2292 6.8352 1.0717 32.8595
GCIY GDSC1 2.4516 11.0629 -0.7109 37.7187
RF-48 GDSC1 2.8657 9.6398 0.3696 32.5203
NCI-N87 GDSC1 3.6981 9.7349 1.0795 25.6578
23132/87 GDSC1 4.1088 6.7804 2.9108 11.9006
Fu97 GDSC1 4.1403 9.0357 1.812 17.781
MKN45 GDSC1 4.2204 8.7611 2.0172 17.9885
HGC-27 GDSC1 4.2605 6.3303 3.2661 8.5498
Hs 746.T GDSC1 4.6933 6.0456 3.7466 3.3561
SNU-5 GDSC1 4.7823 8.5328 2.5868 11.9558
MKN1 GDSC1 4.8374 9.8805 1.9597 16.151
ECC10 GDSC1 5.2441 9.7711 2.3224 12.3907
RERF-GC-1B GDSC1 5.3046 9.9366 2.2855 12.4638
MKN28 GDSC1 5.34 7.6157 3.4264 4.1128
HSC-39 GDSC1 5.3863 6.9089 3.7708 1.6887
TGBC11TKB GDSC1 5.395 7.4482 3.5367 3.2172
OCUM-1 GDSC1 5.5109 11.7921 1.5255 16.6971
NUGC-3 GDSC1 5.6289 10.4646 2.2598 11.6977
SCH GDSC1 6.0609 7.3304 3.9074 0.3477
TMK-1 GDSC1 6.1439 7.8992 3.7284 0.9717
NUGC-4 GDSC1 6.4583 8.6035 3.5919 1.2966
SNU-16 GDSC1 6.533 7.7006 3.9495 0.1028
MKN7 GDSC1 6.8932 12.9811 1.9016 10.7834
SNG-M GDSC1 4.162 5.0937 3.7958 4.7671
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
K5 GDSC1 3.5722 9.5626 1.0533 26.3234
BHT-101 GDSC1 3.7307 9.4625 1.2437 24.6552
8505C GDSC1 3.8358 7.914 2.1062 18.9173
CAL-62 GDSC1 3.9616 8.5295 1.9108 19.7113
TT2609-C02 GDSC1 4.9456 8.9689 2.4955 12.0924
TT GDSC1 5.0814 6.775 3.6558 3.0562
ML-1 [Human leukemia] GDSC1 5.3208 8.2792 3.1011 5.8398
KMH-2 GDSC1 5.4093 10.3273 2.1702 11.6913
B-CPAP GDSC1 5.5726 11.2049 1.8589 14.481
CGTH-W-1 GDSC1 5.6211 10.187 2.3888 10.8396
HTC-C3 GDSC1 5.7752 13.7269 0.7688 19.9754
IHH-4 GDSC1 6.0157 9.1621 3.1252 4.2597
8305C GDSC1 6.0541 10.3659 2.5928 8.32
ASH-3 GDSC1 6.1622 8.1769 3.6267 1.2896
FTC-133 GDSC1 6.2743 9.1665 3.268 3.3564
WRO GDSC1 6.5158 8.1667 3.7811 0.4933
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BICR 22 GDSC1 -0.2056 6.8027 -1.464 53.6607
SCC-9 GDSC1 0.4952 3.2338 0.3846 48.0024
BB30-HNC GDSC1 1.2749 5.256 0.7018 40.526
SCC-15 GDSC1 1.458 5.0408 0.9742 34.4142
OSC-20 GDSC1 1.8097 4.993 1.3715 30.4613
UPCI-SCC-090 GDSC1 2.1944 6.3807 1.2348 32.2715
BHY GDSC1 2.3613 6.2299 1.4724 30.0562
OSC-19 GDSC1 2.4818 7.8996 0.8373 32.5266
NCI-H3118 GDSC1 2.5624 6.0679 1.7502 24.5315
DOK GDSC1 2.5802 10.3578 -0.2471 35.9088
HSC-4 GDSC1 3.1325 7.8637 1.4831 23.5446
JHU-011 GDSC1 3.4908 19.0931 -3.7672 39.2932
SCC-25 GDSC1 3.6562 7.0106 2.3892 17.6829
CAL-27 GDSC1 3.8847 13.5752 -0.674 31.8885
LB771-HNC GDSC1 3.9294 7.9789 2.1569 18.1831
HSC-2 GDSC1 4.0112 5.3887 3.5117 7.6119
FaDu GDSC1 4.0748 11.6088 0.4706 27.0309
PCI-06A GDSC1 4.1366 9.6265 1.5137 21.4885
CAL-33 GDSC1 4.2167 12.5892 0.1003 28.0268
PCI-04B GDSC1 4.2175 11.5944 0.5983 25.9303
PCI-15A GDSC1 4.2655 7.6451 2.6131 13.5735
Ca9-22 GDSC1 4.3463 11.8112 0.5976 25.4597
HSC-3 GDSC1 4.5364 5.5695 3.8666 2.8845
Detroit 562 GDSC1 4.5513 7.9013 2.7196 11.7442
SAS GDSC1 4.6247 14.1067 -0.3205 28.1786
BICR 10 GDSC1 4.6312 6.911 3.2753 7.1956
BB49-HNC GDSC1 4.7638 10.8122 1.4373 19.6332
SAT [Human HNSCC] GDSC1 4.767 15.5343 -0.9179 29.6815
PCI-38 GDSC1 4.9015 7.6279 3.1236 7.5324
BICR 31 GDSC1 5.0658 13.1603 0.5063 23.4025
HO-1-N-1 GDSC1 5.7182 11.0996 2.0145 13.0676
SCC-4 GDSC1 5.9398 10.8167 2.3038 10.561
KON GDSC1 5.9828 7.8605 3.6705 1.4296
PCI-30 GDSC1 6.0894 9.6192 2.9612 5.1248
SKN-3 GDSC1 6.0979 15.9445 -0.0839 22.8302
BICR 78 GDSC1 6.0994 14.7435 0.508 20.287
HO-1-u-1 GDSC1 6.4503 8.3421 3.6895 0.7784
JHU-022 GDSC1 6.4896 14.3298 0.9891 16.8857
PE/CA-PJ15 GDSC1 6.9252 13.8913 1.494 11.9848
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KU-19-19 GDSC1 0.4122 4.811 -0.0878 49.1412
BFTC-905 GDSC1 1.7753 14.1662 -2.8558 43.8445
CAL-29 GDSC1 2.5477 9.0147 0.3716 34.0477
5637 GDSC1 2.7401 9.7689 0.1893 33.7678
RT-112 GDSC1 3.1578 6.0638 2.359 20.1932
HT-1376 GDSC1 3.7189 7.411 2.25 16.5249
J82 GDSC1 3.996 4.771 3.7899 5.5472
UM-UC-3 GDSC1 4.0047 14.1887 -0.8783 32.0679
647V GDSC1 4.2558 11.1256 0.8649 24.5313
639V GDSC1 4.7757 7.6526 3.018 8.7275
HT-1197 GDSC1 5.2216 9.494 2.442 11.6202
SW1710 GDSC1 5.6283 14.2837 0.3834 22.208
SW780 GDSC1 6.5784 8.3312 3.7458 0.5724
RT-4 GDSC1 6.6956 8.5857 3.6988 0.5892
T24 GDSC1 7.7666 20.5404 -1.1268 22.4857
TCCSUP GDSC1 8.4842 16.715 1.1546 11.5378
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OVMIU GDSC1 1.0391 6.7418 -0.1227 44.2191
PA-1 GDSC1 1.0683 2.9652 1.0294 40.8723
SW954 GDSC1 1.4434 7.6033 -0.071 41.4803
ME-180 GDSC1 2.3008 7.3095 0.9306 33.0989
Ca Ski GDSC1 2.7448 7.0137 1.5099 27.764
KGN GDSC1 3.3853 5.9759 2.6262 17.1658
CAL-39 GDSC1 3.4074 6.4985 2.4017 18.7039
ACC-OV7 GDSC1 3.5331 9.0329 1.2806 25.297
DoTc2 4510 GDSC1 3.9758 10.583 0.8985 25.4409
PEO1 GDSC1 4.1148 7.9161 2.3495 16.0846
C-33 A GDSC1 4.1974 10.8167 0.9702 24.2273
HeLa GDSC1 4.3223 5.1311 3.9177 3.187
BPH-1 GDSC1 4.3278 9.9812 1.4972 20.8552
JAR GDSC1 4.4379 5.8961 3.6292 5.0573
NCC-IT GDSC1 4.562 10.7457 1.3079 21.0816
NEC8 GDSC1 4.6154 5.9345 3.7452 3.5892
LB831-BLC GDSC1 4.7925 9.8905 1.9194 16.5675
HT-3 GDSC1 4.8045 7.2766 3.2249 7.0455
JEG-3 GDSC1 4.8775 7.573 3.1329 7.5327
HEC-1 GDSC1 5.0358 8.9817 2.5569 11.3646
OMC-1 [Human cervical carcinoma] GDSC1 5.2615 13.2429 0.6183 22.2605
JHOS-3 GDSC1 5.3776 8.513 3.0275 6.9282
MS751 GDSC1 5.4111 7.9284 3.3254 4.6745
HEY GDSC1 5.4438 8.6927 2.9859 7.0605
OVCA420 GDSC1 5.4867 8.1284 3.2797 4.8278
SiSo GDSC1 5.5925 8.0858 3.3639 4.0023
NT2-D1 GDSC1 5.6228 12.7271 1.1481 18.4815
C-4-I GDSC1 5.6461 7.4987 3.6541 1.9907
SW962 GDSC1 5.6779 7.9041 3.4948 2.9487
SiHa GDSC1 5.9243 7.206 3.8992 0.4532
DSH1 GDSC1 6.1161 8.0907 3.64 1.4303
SKG-IIIa GDSC1 6.1493 7.7758 3.7781 0.7523
OV17R GDSC1 6.3787 8.5549 3.5752 1.4615
OVCA433 GDSC1 6.4048 9.1315 3.351 2.6503
SW756 GDSC1 6.6566 8.2979 3.7879 0.4013
UWB1.289 GDSC1 6.9737 15.1739 0.9152 16.0336
SKN GDSC1 7.0658 9.5382 3.4939 1.05
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
2 Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5295-8.