Details of the Drug

General Information of Drug (ID: DMW4LTI)

Drug Name

Votucalis

Synonyms

EV-131; REV-131; Tick-derived compounds, Evolutec; Votucalis (intranasal), Evolutec; Votucalis (ophthalmic), Evolutec; Votucalis (respiratory disease), Evolutec; REV-131 (intranasal), Evolutec; REV-131 (ophthalmic), Evolutec; REV-131 (respiratory disease), Evolutec

Indication

Disease Entry	ICD 11	Status	REF
Allergic rhinitis	CA08.0	Phase 2	[1]
------------------------------------------------------------------------------------

Cross-matching ID

UNII: V94JSH9V48
DrugBank ID: DB05032
TTD ID: D09ZMV

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Histamine receptor (HR)	TT7CXIM	NOUNIPROTAC	Antagonist	[2]

------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT00353964) Safety and Efficacy Study of rEV131 in the Treatment of Ocular Inflammation After Cataract Surgery. U.S. National Institutes of Health.
2	CA patent application no. 520580, Histamine binding compounds for treatment method for disease conditions mediated by neutrophils.