Details of the Drug

General Information of Drug (ID: DMW50NF)

Drug Name
LE-SN38
Synonyms
7-Ethyl-10-hydroxycamptothecin; 86639-52-3; SN-38; SN 38 lactone; 7-Ethyl-10-hydroxy-camptothecin; SN 38; 10-Hydroxy-7-ethylcamptothecin; 7-Ethyl-10-hydroxycamptothecine; SN38; 7-Ethyl-10-hydroxy-20(S)-camptothecin; UNII-0H43101T0J; Captothecin, 7-ethyl-10-hydroxy-; CHEBI:8988; (S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 7-Ethyl-10-hydroxy camptothecin; NSC673596; 0H43101T0J; (+)-7-ETHYL-10-HYDROXYCAMPTOTHECIN; 113015-38-6
Indication
Disease Entry ICD 11 Status REF
Colorectal cancer 2B91.Z Phase 2 [1]
Solid tumour/cancer 2A00-2F9Z Phase 2 [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 392.4
Logarithm of the Partition Coefficient (xlogp) 1.4
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C22H20N2O5
IUPAC Name
(19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
Canonical SMILES
CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)O
InChI
InChI=1S/C22H20N2O5/c1-3-12-13-7-11(25)5-6-17(13)23-19-14(12)9-24-18(19)8-16-15(20(24)26)10-29-21(27)22(16,28)4-2/h5-8,25,28H,3-4,9-10H2,1-2H3/t22-/m0/s1
InChIKey
FJHBVJOVLFPMQE-QFIPXVFZSA-N
Cross-matching ID
PubChem CID
104842
ChEBI ID
CHEBI:8988
CAS Number
86639-52-3
UNII
0H43101T0J
DrugBank ID
DB05482
TTD ID
D0B6YB
VARIDT ID
DR00161
INTEDE ID
DR0024
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNA topoisomerase I (TOP1) TTGTQHC TOP1_HUMAN Inhibitor [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [4]
Multidrug resistance-associated protein 4 (ABCC4) DTCSGPB MRP4_HUMAN Substrate [5]
Multidrug resistance-associated protein 1 (ABCC1) DTSYQGK MRP1_HUMAN Substrate [6]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [7]
Organic anion transporting polypeptide 1B1 (SLCO1B1) DT3D8F0 SO1B1_HUMAN Substrate [8]
Organic anion transporting polypeptide 1B3 (SLCO1B3) DT9C1TS SO1B3_HUMAN Substrate [9]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Substrate [10]
UDP-glucuronosyltransferase 1A9 (UGT1A9) DE85D2P UD19_HUMAN Substrate [11]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Colorectal cancer
ICD Disease Classification 2B91.Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
DNA topoisomerase I (TOP1) DTT TOP1 6.65E-01 0.2 0.39
Multidrug resistance-associated protein 1 (ABCC1) DTP MRP1 1.90E-30 1.76E-01 7.31E-01
Breast cancer resistance protein (ABCG2) DTP BCRP 3.87E-47 -1.28E+00 -1.63E+00
Multidrug resistance-associated protein 2 (ABCC2) DTP MRP2 1.02E-08 -5.12E-02 -2.22E-01
Multidrug resistance-associated protein 4 (ABCC4) DTP MRP4 1.26E-03 -4.35E-01 -5.28E-01
Organic anion transporting polypeptide 1B3 (SLCO1B3) DTP OATP1B3 3.46E-61 1.83E-01 7.90E-01
Organic anion transporting polypeptide 1B1 (SLCO1B1) DTP OATP1B1 2.80E-34 1.44E-01 9.71E-01
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME UGT1A1 2.33E-02 1.75E-02 8.91E-02
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 -7.7602 -3.4862 -8.1216 34.6723
EW-22 GDSC1; GDSC2 -10.4956 -8.1944 -10.4978 53.9754
EW-3 GDSC1; GDSC2 -10.3709 -5.2214 -10.5918 52.7119
ES7 GDSC1; GDSC2 -10.2853 -8.3829 -10.2859 52.4056
TC71 CTRP2 -10.2551 -7.0758 -10.2569 70.6446
ES8 GDSC1; GDSC2 -10.1355 -8.3056 -10.1359 51.279
TC-71 GDSC1; GDSC2 -9.9919 -8.2806 -9.9922 50.1997
A-673 GDSC1; GDSC2 -9.8858 -7.2645 -9.8955 49.4057
ES1 GDSC1; GDSC2 -9.5586 -7.5803 -9.5604 46.9422
MHH-ES-1 GDSC1; GDSC2; CTRP2 -9.236 -6.4458 -9.2361 62.9886
EW-16 GDSC1; GDSC2 -9.1273 -7.0975 -9.1308 43.7035
ES4 GDSC1; GDSC2 -9.1141 -6.2408 -9.1449 43.6776
EW-7 GDSC1; GDSC2 -9.0292 -6.34 -9.0521 43.0217
SK-ES-1 GDSC1; GDSC2; CTRP2 -8.9955 -6.4106 -8.9963 55.1739
SK-PN-DW GDSC1; GDSC2 -8.929 -7.2879 -8.9298 42.2025
EW-1 GDSC1; GDSC2 -8.8541 -6.7674 -8.8597 41.6552
HuO9 GDSC1; GDSC2 -8.1613 -4.6992 -8.301 36.9036
CADO-ES1 GDSC1; GDSC2; CTRP2 -8.1291 -5.2505 -8.1331 50.0819
EW-11 GDSC1; GDSC2 -7.5721 -2.6939 -8.1459 34.003
EW-12 GDSC2 -7.5649 -3.3466 -7.5781 90.7876
ES5 GDSC1; GDSC2 -7.0408 10.9982 -10.7234 57.1546
CAL-72 GDSC1; GDSC2 -6.3525 -0.5803 -7.6376 27.8355
SaOS-2 GDSC1; GDSC2; CTRP2 -6.3487 -2.5048 -6.4219 39.7898
EW-24 GDSC1; GDSC2 -5.7867 -0.3836 -7.1403 24.1108
NY GDSC1; GDSC2 -5.6094 -0.2431 -7.023 23.0924
EW-13 GDSC1; GDSC2 -5.1927 4.7967 -9.0292 28.8055
SJSA-1 GDSC1; GDSC2 -4.9831 -1.6811 -5.7467 15.7322
CAL-78 GDSC1; GDSC2; CTRP2 -4.3238 0.0993 -4.6798 28.7486
MG-63 GDSC1; GDSC2; CTRP2 -4.2078 0.4719 -4.6525 28.3382
H-EMC-SS GDSC1; GDSC2 -3.9973 3.4061 -7.2641 19.6526
HuO-3N1 GDSC1; GDSC2 -3.6013 5.0068 -7.7214 20.4611
HOS GDSC1; GDSC2; CTRP2 -3.5958 2.7987 -4.796 27.0954
ES6 GDSC1; GDSC2 -3.3174 1.8011 -5.8797 12.0774
NOS-1 [Human HNSCC] GDSC1; GDSC2 -2.3934 5.324 -6.8976 14.6015
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 -2.2554 5.3452 -4.5371 22.9903
CHSA0011 GDSC1; GDSC2 -1.2332 5.2595 -2.2862 32.3438
EW-18 GDSC1; GDSC2 -0.2131 14.2891 -9.6901 20.1188
CHSA8926 GDSC1; GDSC2 -0.1268 10.0236 -7.5563 13.1474
SW1353 CTRP2 -0.0201 3.8289 -1.6891 9.526
U-CH2 GDSC2 0.775 8.3526 -1.5382 35.2659
U2OS GDSC1; GDSC2; CTRP2; CTRP1 0.9906 6.326 -0.39 15.6377
CHSA0108 GDSC1; GDSC2 1.065 13.9786 -3.9872 30.2763
Hs 888.T CTRP2 1.491 7.5523 -2.3288 9.3861
Hs 822.T CTRP2 3.1341 12.4883 -3.5621 11.5452
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 204 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 -7.5158 -1.5761 -7.7927 52.4639
JM1 GDSC1; GDSC2; CTRP2 -10.2426 -8.8464 -10.2426 75.7925
Ri-1 CTRP2 -15.7715 -1.9513 -16.6693 77.7658
MHH-CALL-4 GDSC2; CTRP2 -15.367 0.2808 -16.3312 77.3555
MOLT-3 CTRP2 -12.0337 -10.9173 -12.0337 82.9881
CML-T1 GDSC1; GDSC2; CTRP2 -10.9026 -9.8818 -10.9026 66.4089
SU-DHL-5 GDSC1; GDSC2; CTRP1 -10.7816 -9.5197 -10.7816 65.3439
MOLT-16 GDSC1; GDSC2; CTRP2 -10.5212 -8.8128 -10.5212 64.1617
NKM-1 GDSC1; GDSC2 -10.3816 -6.1369 -10.4791 52.9363
BV-173 GDSC1; GDSC2 -10.2193 -6.8871 -10.2511 51.8636
SUP-M2 GDSC1; GDSC2 -10.1248 -8.4408 -10.125 51.1991
MOLT-4 GDSC1; GDSC2 -10.0568 -8.2523 -10.0573 50.6877
CRO-AP2 GDSC1; GDSC2 -10.0455 -4.5778 -10.0685 80.163
SUP-T1 GDSC1; GDSC2; CTRP2 -9.971 -0.1716 -10.7709 58.0404
Mino CTRP2 -9.8594 -7.9279 -9.8594 68.4418
CCRF-CEM GDSC1; GDSC2 -9.8295 -5.9337 -9.9176 49.0246
JVM-3 GDSC1; GDSC2; CTRP2 -9.8008 -7.6838 -9.8009 59.9182
DoHH2 GDSC1; GDSC2; CTRP2 -9.7923 -8.1382 -9.7923 73.273
ALL-SIL GDSC1; GDSC2; CTRP2 -9.7839 -8.0757 -9.7839 59.8226
Karpas-231 GDSC1; GDSC2 -9.7145 -8.4368 -9.7145 48.1119
SR GDSC1; GDSC2 -9.6808 -7.2484 -9.6879 47.8688
SUP-B15 GDSC1; GDSC2; CTRP2 -9.6327 -7.8679 -9.6327 58.9324
NU-DHL-1 CTRP2 -9.5815 -5.2443 -9.6067 65.6829
Reh GDSC1; GDSC2 -9.5698 -7.8501 -9.5703 47.0237
IM-9 GDSC1; GDSC2 -9.5437 -6.6654 -9.5662 46.8662
A3/Kawakami GDSC1; GDSC2 -9.5115 -7.6054 -9.5129 46.5874
P12-Ichikawa GDSC1; GDSC2; CTRP2 -9.5012 -8.6514 -9.5012 58.1592
SCC-3 GDSC2 -9.4186 -7.7918 -9.4527 28.0174
DB GDSC1; GDSC2; CTRP2 -9.3772 -5.7505 -9.3861 57.3347
QIMR-WIL GDSC1; GDSC2 -9.3453 -6.1771 -9.3457 79.8727
MV4-11 GDSC1; GDSC2; CTRP2 -9.341 -7.4784 -9.341 57.2151
MOLT-13 GDSC1; GDSC2 -9.3356 -6.6726 -9.3525 45.3014
P32/ISH GDSC1; GDSC2 -9.3273 -7.6115 -9.328 45.1998
HD-MY-Z CTRP2 -9.309 -2.9135 -9.5106 62.5208
Hs 445 GDSC1; GDSC2 -9.2746 -7.7525 -9.2757 40.3128
Namalwa GDSC1; GDSC2 -9.2604 -7.6224 -9.2609 44.6955
RPMI-8402 GDSC1; GDSC2; CTRP2 -9.2228 -8.2956 -9.2228 56.5203
KOPN-8 GDSC1; GDSC2 -9.2005 -5.8624 -9.2627 44.3928
KE-37 GDSC1; GDSC2; CTRP2 -9.1417 -8.3554 -9.1417 56.0429
KG-1 GDSC1; GDSC2 -9.1316 -5.6469 -9.211 43.9205
Ci-1 CTRP2 -9.1094 -5.3103 -9.1237 63.0211
JSC-1 GDSC1; GDSC2 -9.0819 -7.161 -9.0843 43.3582
SU-DHL-1 GDSC2; CTRP2 -9.0326 -8.644 -9.0326 69.0355
CTV-1 GDSC1; GDSC2 -9.027 -7.0924 -9.0297 42.9466
NB4 GDSC1; GDSC2 -8.9962 -7.3966 -8.9962 78.6928
OCI-Ly19 GDSC1; GDSC2 -8.9783 -2.2974 -9.0829 73.3774
SKM-1 GDSC1; GDSC2; CTRP1 -8.9505 -5.977 -8.9508 77.7615
L-540 GDSC1; GDSC2 -8.9498 -6.9298 -8.9538 42.3698
OCI-AML-2 GDSC1; GDSC2 -8.8649 -7.1361 -8.8662 41.722
DEL GDSC1; GDSC2; CTRP2 -8.8441 -6.6946 -8.8442 54.2891
RCH-ACV GDSC1; GDSC2 -8.8406 -7.312 -8.8406 77.7169
HAL-01 GDSC1; GDSC2 -8.8343 -6.285 -8.8542 41.5513
GR-ST GDSC1; GDSC2 -8.8224 -3.9635 -9.1625 42.2419
MOTN-1 CTRP2 -8.8134 -5.784 -8.8169 61.3452
697 GDSC1; GDSC2 -8.7533 -7.6617 -8.7534 40.8778
RPMI-8866 GDSC1; GDSC2 -8.7284 -5.6562 -8.7858 40.8709
CTB-1 GDSC1; GDSC2 -8.7263 -3.0673 -8.7738 73.5266
MOLM-13 GDSC1; GDSC2; CTRP2 -8.7218 -6.0156 -8.7233 53.5636
H9 GDSC1; GDSC2 -8.7212 -6.843 -8.7242 40.6466
SUP-HD1 GDSC1; GDSC2; CTRP2 -8.6894 -5.0573 -8.703 53.34
EoL-1 GDSC1; GDSC2 -8.6047 -5.7674 -8.6472 39.9005
Raji GDSC1; GDSC2 -8.5421 -5.6955 -8.5874 39.4407
MHH-CALL-2 GDSC1; GDSC2 -8.5383 -5.8225 -8.5741 39.3814
ATN-1 GDSC1; GDSC2 -8.475 -7.0157 -8.4755 38.7849
Granta-519 GDSC1; GDSC2 -8.4714 -5.4324 -8.5367 38.9757
RS4;11 GDSC1; GDSC2 -8.4327 -6.6373 -8.4358 38.4762
SEM CTRP2 -8.4165 -6.9622 -8.4165 58.8189
Karpas-1106P GDSC1; GDSC2 -8.4102 -3.5611 -8.8114 39.4739
NU-DUL-1 GDSC1; GDSC2; CTRP1 -8.4061 -6.116 -8.4062 74.8154
JeKo-1 GDSC1; GDSC2; CTRP2 -8.3239 -4.838 -8.326 64.9102
ML-2 GDSC1; GDSC2 -8.2662 -6.0581 -8.2808 37.2646
EM-2 GDSC1; GDSC2; CTRP2 -8.2297 -6.2277 -8.2298 50.674
ARH-77 GDSC1; GDSC2 -8.2098 -4.5012 -8.3867 37.3825
Jurkat GDSC1; GDSC2; CTRP2 -8.1736 -6.7276 -8.1736 50.3436
SET-2 CTRP2 -8.1695 -7.5646 -8.1695 57.1675
MY-M12 GDSC1; GDSC2 -8.1372 -6.1766 -8.1372 78.0829
WIL2 NS GDSC1; GDSC2 -8.0989 -6.2095 -8.1055 35.9767
CESS GDSC1; GDSC2 -8.0921 -5.7325 -8.1171 35.9928
Kasumi-2 CTRP2 -8.0909 -7.3476 -8.0909 56.642
KO52 CTRP2 -8.0835 -6.5724 -8.0835 56.5922
HC-1 GDSC1; GDSC2 -8.0664 -5.773 -8.0883 35.7883
TALL-1 [Human adult T-ALL] GDSC2 -8.0533 0.1933 -8.3992 82.0843
DND-41 GDSC1; GDSC2 -8.0341 -5.971 -8.0464 35.5103
BALL-1 GDSC1; GDSC2 -8.0236 -5.239 -8.0842 35.6055
HEL 92.1.7 CTRP2 -7.9985 -7.6294 -7.9985 56.0239
LC4-1 GDSC1; GDSC2 -7.9593 -2.658 -8.5786 36.8843
PF-382 GDSC1; GDSC2; CTRP2 -7.9576 -5.8502 -7.9579 49.0726
NOMO-1 GDSC1; GDSC2; CTRP1 -7.9392 -5.2846 -7.942 48.4426
KE-97 CTRP2; CTRP1 -7.9308 -5.9851 -7.9308 66.4177
OCI-AML-5 GDSC1; GDSC2; CTRP2 -7.9153 -6.1207 -7.9154 48.8234
NALM-6 GDSC1; GDSC2; CTRP2 -7.9051 -5.8997 -7.9053 48.7633
MOLM-16 GDSC1; GDSC2; CTRP2; CTRP1 -7.8982 -3.5383 -7.9121 62.3584
NK-92MI GDSC2 -7.8285 -4.6714 -7.8298 94.766
BC-1 GDSC1; GDSC2 -7.8155 -2.6636 -8.4202 35.8312
BONNA-12 GDSC2 -7.7475 -1.8258 -7.8348 86.6726
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 -7.7457 -5.3 -7.7472 47.8268
P30/OHK GDSC1; GDSC2 -7.7113 -6.3556 -7.7123 33.0392
WSU-NHL GDSC1; GDSC2 -7.6968 -3.6853 -8.0022 34.0195
SU-DHL-6 GDSC1; GDSC2 -7.6478 -3.6419 -7.9595 33.6802
AML-193 CTRP2 -7.6076 -6.0793 -7.6076 53.4096
ALL-PO GDSC1; GDSC2 -7.5992 -2.472 -8.2468 34.4313
HL-60 GDSC1; GDSC2 -7.59 -6.3318 -7.5907 32.1249
KMS-27 CTRP2 -7.5552 -6.4118 -7.5552 53.0592
TK [Human B-cell lymphoma] GDSC1; GDSC2 -7.5542 -5.6086 -7.5689 31.9083
RPMI-6666 GDSC1; GDSC2 -7.554 -1.3255 -8.6061 35.3187
PL21 CTRP1 -7.525 -4.4338 -7.5365 90.7011
A4/Fukuda GDSC1; GDSC2 -7.5032 -4.9392 -7.5663 31.7058
MM1.S GDSC1; GDSC2 -7.4143 -5.1638 -7.4513 30.9392
BL-70 CTRP1 -7.3563 -0.4854 -7.4668 80.3844
BE-13 GDSC1; GDSC2 -7.2849 0.9413 -9.2582 35.9758
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 -7.2609 -4.5976 -7.2654 44.9811
MLMA GDSC1; GDSC2 -7.2199 -3.3756 -7.5614 30.6232
EB2 GDSC1; GDSC2 -7.1431 -5.0732 -7.1752 28.8803
VAL GDSC1; GDSC2 -7.1068 -2.8475 -7.5911 30.3138
Sc-1 GDSC1 -7.0844 -4.9925 -7.1204 41.964
BC-3 GDSC2 -7.084 -2.6834 -7.1061 88.2708
JVM-2 GDSC1; GDSC2; CTRP2 -7.0729 -1.2366 -7.3763 44.3573
HEL GDSC1; GDSC2; CTRP2 -6.8908 -5.7265 -6.8908 57.0671
JURL-MK1 GDSC1; GDSC2; CTRP2 -6.8585 -5.0319 -6.8587 42.6029
SU-DHL-16 GDSC1; GDSC2 -6.8019 -2.8972 -6.8138 64.255
Jiyoye GDSC1; GDSC2 -6.7679 -2.8511 -7.221 27.6947
OCI-M1 GDSC1; GDSC2 -6.7484 -4.5681 -6.8093 26.0207
Karpas-299 GDSC1; GDSC2; CTRP2 -6.6439 -0.4945 -7.0657 42.1656
SUP-B8 GDSC1; GDSC2 -6.624 -2.1858 -6.6531 62.9236
Daudi GDSC1; GDSC2; CTRP2 -6.5653 -3.5624 -6.5822 40.9208
CMK GDSC1 -6.5383 -4.041 -6.6651 36.3836
TUR GDSC1; GDSC2 -6.5305 -3.904 -6.6835 24.7402
Farage GDSC1; GDSC2 -6.5026 -2.7052 -6.5143 62.4639
Ki-JK CTRP2 -6.4966 -2.968 -6.5404 46.0569
KMOE-2 GDSC1; GDSC2 -6.4839 -1.2466 -7.4988 27.7657
GDM-1 GDSC1; GDSC2; CTRP1 -6.4664 -2.7275 -6.5326 39.8534
P31/FUJ GDSC1; GDSC2; CTRP2 -6.4536 -5.4642 -6.4536 40.2189
VL51 GDSC1; GDSC2 -6.4274 0.7796 -8.3113 30.3827
THP-1 GDSC1; GDSC2; CTRP1 -6.4131 -5.1366 -6.4131 62.229
MHH-PREB-1 GDSC1; GDSC2 -6.3339 -1.069 -7.4133 26.9382
MHH-CALL-3 CTRP2 -6.3207 21.0788 -15.9743 48.4876
MC116 GDSC1; GDSC2; CTRP1 -6.2989 -0.8446 -6.3466 64.5822
KMS-20 CTRP2 -6.2282 -4.7337 -6.2283 44.1849
KMS-26 CTRP2 -6.2157 -4.2745 -6.2167 44.104
U-698-M GDSC1; GDSC2 -6.2149 -1.7993 -6.9947 24.9048
KHM-1B CTRP2 -6.1924 -4.0341 -6.1949 43.9522
KY821 GDSC1; GDSC2 -6.1829 -2.2914 -6.7758 23.9122
MOLP-8 GDSC1; GDSC2 -6.1127 -1.01 -7.2062 25.4092
SU-DHL-4 GDSC1; GDSC2; CTRP1 -6.0838 -3.8139 -6.084 60.1092
HuT 78 CTRP2 -6.0641 -3.0533 -6.0888 43.1516
EJM GDSC1; GDSC2; CTRP1 -6.016 -3.4425 -6.0275 37.0353
TF-1 CTRP2 -5.9376 -1.8611 -6.057 42.5293
PL-21 GDSC1; GDSC2 -5.9148 -2.5694 -5.9219 58.9229
NCI-H929 GDSC1; GDSC2; CTRP2 -5.8788 -2.2824 -5.9488 37.0297
Ramos.2G6.4C10 GDSC1; GDSC2 -5.84 -0.2392 -7.2589 24.7457
KMS-21-BM CTRP2 -5.8397 -4.059 -5.8404 41.5885
KMS-12-BM GDSC1; GDSC2 -5.8283 -2.7356 -6.2371 20.5082
RL GDSC1; GDSC2; CTRP2 -5.7856 -1.8034 -5.8093 50.8789
L-1236 GDSC1; GDSC2 -5.6873 0.0307 -7.2255 24.1413
Kasumi-1 GDSC1; GDSC2; CTRP2 -5.62 -0.3207 -5.7356 49.9681
YT GDSC1; GDSC2 -5.5441 0.8539 -7.4623 24.6256
M-07e CTRP2 -5.5331 -2.972 -5.5476 39.5814
AMO1 GDSC1; CTRP2; CTRP1 -5.3572 -1.864 -5.4411 38.6115
ST486 GDSC1; GDSC2 -5.3188 1.8124 -7.6973 24.8413
U-937 CTRP2; CTRP1 -5.1278 -3.4355 -5.129 36.8292
MEG-01 GDSC1; GDSC2 -5.1034 1.8201 -7.4953 23.4695
LAMA-84 GDSC1; GDSC2; CTRP2 -5.101 -2.9969 -5.1072 32.2747
EHEB GDSC1; CTRP2 -5.0902 -0.0176 -5.4863 37.7033
SU-DHL-10 GDSC1; GDSC2 -5.0848 -2.1235 -6.1073 11.1387
OCI-Ly10 CTRP1 -5.076 -0.7531 -5.3277 67.5019
Mono-Mac-6 GDSC1; GDSC2; CTRP2 -5.0745 7.0441 -8.1425 38.589
NCO2 CTRP2 -5.0234 -2.8956 -5.0307 36.1511
Karpas-422 GDSC1; GDSC2 -5.0176 0.5901 -6.8235 20.532
SIG-M5 GDSC2 -5.0105 -3.5682 -5.0105 83.0907
P3HR-1 CTRP2; CTRP1 -4.7358 2.4124 -5.0283 50.2461
RPMI-8226 GDSC1; GDSC2; CTRP2; CTRP1 -4.7162 0.6517 -5.2584 31.5653
ROS-50 GDSC1; GDSC2 -4.7058 -0.627 -4.7543 51.2772
K-562 GDSC1; GDSC2 -4.6349 1.1301 -6.7186 19.0355
MN-60 GDSC1; GDSC2 -4.5558 1.1695 -6.6637 18.5896
KCL-22 GDSC1; GDSC2; CTRP2 -4.5534 -1.0235 -4.696 29.4567
JJN-3 GDSC1; GDSC2; CTRP2 -4.5445 1.5721 -5.3617 31.3482
GA-10 GDSC1; GDSC2 -4.5256 2.7742 -7.4232 21.6191
KM-H2 GDSC1; GDSC2; CTRP2 -4.4726 -2.0031 -4.5022 28.6448
F-36P CTRP2 -4.4716 3.8662 -6.152 36.9609
OCI-Ly7 GDSC1; GDSC2 -4.4014 -3.3741 -4.4014 49.3697
HDLM-2 GDSC1; GDSC2; CTRP2 -4.3083 0.0112 -4.6409 28.5882
L-363 GDSC1; GDSC2 -4.277 0.8522 -6.2501 16.0481
Peer CTRP2 -4.2248 -0.1065 -4.5216 31.7677
CA46 GDSC1; GDSC2 -4.1584 0.2528 -5.8467 13.916
Loucy GDSC1; GDSC2 -4.1283 18.7162 -15.02 36.7374
RC-K8 GDSC1; GDSC2 -4.065 0.1464 -5.7085 13.0437
SK-MM-2 GDSC1; GDSC2 -3.8498 -1.0176 -4.939 8.9121
L-428 GDSC1; GDSC2; CTRP2 -3.8456 -1.888 -3.861 24.9116
ME1 CTRP2 -3.8364 3.3272 -5.2631 32.6823
SU-DHL-8 GDSC1; GDSC2 -3.8156 0.7998 -6.474 9.8744
HT GDSC1; GDSC2; CTRP2; CTRP1 -3.6604 -0.2235 -3.6711 44.8545
Ku812 GDSC1; GDSC2; CTRP2; CTRP1 -3.4739 -0.3373 -3.4804 39.8125
Karpas-45 GDSC1; GDSC2 -3.0712 1.4461 -5.5004 9.7892
DG-75 GDSC1; GDSC2 -3.0193 2.1287 -5.7994 11.0674
ME1 GDSC1; GDSC2 -2.682 3.313 -6.1223 11.8422
KMS-11 GDSC1; GDSC2; CTRP2; CTRP1 -2.6202 5.6119 -3.9062 36.2593
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 -2.5359 5.7099 -4.9839 25.0027
U266B1 GDSC1; GDSC2; CTRP2 -1.9479 4.1915 -3.6966 19.5483
OPM-2 GDSC1; GDSC2 -1.2514 3.7638 -5.3237 5.8048
LP-1 GDSC1; GDSC2; CTRP1 -1.2021 2.9572 -1.5206 29.9457
KMM-1 CTRP2 2.3502 6.167 -1.0844 3.2369
Karpas-620 GDSC1; GDSC2; CTRP2 2.5113 4.2795 -0.2072 0.3233
Toledo CTRP2 2.6088 14.6008 -4.9703 17.0652
BL-41 GDSC1; GDSC2; CTRP2 4.1893 17.3921 -5.1999 13.958
⏷ Show the Full List of 204 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 -5.5517 -3.0131 -5.5653 39.7028
KYSE-270 GDSC1; GDSC2 -7.474 -4.6243 -7.5756 31.6305
TE-5 GDSC1; GDSC2; CTRP2 -6.9274 -3.3165 -6.9655 43.0939
TE-8 GDSC1; GDSC2 -6.7997 -3.1908 -7.154 27.5477
T.T GDSC1; GDSC2 -6.2885 -1.9727 -7.007 25.1993
EC-GI-10 GDSC1; GDSC2; CTRP2 -6.229 -1.2019 -6.4706 39.4831
TE-15 GDSC1; GDSC2 -6.1984 -2.3897 -6.7573 23.8885
TE-4 GDSC1; GDSC2 -5.5356 -1.3547 -6.4593 20.5116
KYSE-510 GDSC1; GDSC2; CTRP2 -5.2988 -2.8837 -5.2997 48.1726
TE-11 GDSC1; GDSC2 -4.9595 0.4139 -5.1196 52.7054
OE21 GDSC1; GDSC2; CTRP2 -4.1167 -0.5256 -4.3132 27.0532
TE-14 CTRP2 -4.0979 2.0069 -5.0314 32.8966
TE-9 GDSC1; GDSC2; CTRP2 -3.6882 -0.3077 -3.8928 24.5598
KYSE-410 GDSC1; GDSC2; CTRP2; CTRP1 -3.4198 1.8917 -3.5523 39.811
TE-6 GDSC1; GDSC2 -3.0449 -0.5112 -4.5036 5.0357
KYSE-150 GDSC1; GDSC2; CTRP2 -2.4525 3.0799 -3.713 20.7814
TE-10 GDSC1; GDSC2; CTRP2 -2.3161 0.9239 -2.3792 31.6805
COLO 680N GDSC1; GDSC2; CTRP2 -2.2168 3.4002 -3.6101 19.8769
OE33 GDSC1; GDSC2; CTRP2 -1.8029 4.7274 -3.803 19.5809
KYSE-520 GDSC1; GDSC2; CTRP2 -1.5318 2.1791 -2.3728 14.0248
KYSE-180 GDSC1; GDSC2; CTRP2 -1.1299 0.4915 -1.2999 9.4086
TE-1 GDSC1; GDSC2; CTRP2 -0.7788 7.6597 -4.2665 18.9693
KYSE-140 GDSC1; GDSC2; CTRP2; CTRP1 -0.0048 4.4804 -0.2998 24.596
KYSE-450 GDSC1; GDSC2; CTRP2; CTRP1 0.2334 2.3868 0.2213 22.8345
OE19 GDSC1; GDSC2; CTRP2 1.4234 3.1503 -0.2639 1.0861
KYSE-30 CTRP2 1.9478 12.7627 -4.5593 16.8583
KYSE-70 GDSC1; GDSC2; CTRP2 4.665 21.7576 -6.9835 17.9616
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 0.1096 7.1345 -3.2261 15.5236
HuP-T4 GDSC1; GDSC2; CTRP1 -8.5548 -5.7547 -8.5548 63.0752
KP-4 GDSC1; GDSC2; CTRP2 -6.1248 -2.8145 -6.1645 38.3921
Panc 03.27 GDSC1; GDSC2; CTRP2; CTRP1 -5.9087 -1.2159 -5.932 50.9462
SU.86.86 GDSC1; GDSC2 -5.4956 -0.9994 -6.571 20.8646
Capan-1 GDSC1; GDSC2; CTRP2 -5.0441 0.5113 -5.5761 33.4167
SW1990 GDSC1; GDSC2; CTRP2 -4.9562 0.0013 -5.3449 32.5215
Panc 08.13 GDSC1; GDSC2; CTRP2 -4.8202 -1.7816 -4.8832 30.7892
PL4 GDSC1; GDSC2 -4.7254 -0.5237 -6.0123 16.1764
Panc 10.05 GDSC1; GDSC2; CTRP2; CTRP1 -4.5603 -0.3945 -4.5821 44.8126
MIA PaCa-2 GDSC1; GDSC2; CTRP2 -4.5177 0.4582 -4.9869 30.2112
BxPC-3 GDSC1; GDSC2; CTRP2 -3.943 -0.6757 -4.0973 25.9035
KP-1N GDSC1; GDSC2 -3.4098 0.1301 -5.1217 8.7366
SUIT-2 GDSC1; GDSC2; CTRP2; CTRP1 -3.3697 3.2613 -3.7023 39.9331
PSN1 GDSC1; GDSC2; CTRP2 -3.3118 4.0864 -5.0353 27.0605
HuP-T3 GDSC1; GDSC2; CTRP2 -3.2064 2.0976 -4.1083 23.9495
YAPC GDSC1; GDSC2; CTRP2 -3.0198 3.9432 -4.6722 25.241
MZ-PC-1 GDSC1; GDSC2 -2.2501 13.7248 -7.0283 42.9752
DAN-G GDSC1; GDSC2; CTRP2 -2.249 3.9538 -3.8903 20.8886
Panc 02.03 GDSC1; GDSC2; CTRP2 -2.1597 4.1755 -3.901 20.7165
Hs 766T GDSC1; GDSC2; CTRP2 -1.9263 5.9991 -4.5255 22.2082
CFPAC-1 GDSC1; GDSC2; CTRP2; CTRP1 -1.8917 7.5777 -3.2954 35.3852
Capan-2 GDSC1; GDSC2; CTRP2; CTRP1 -1.6487 1.296 -1.6646 31.4694
HPAC GDSC1; GDSC2; CTRP2; CTRP1 -1.39 10.7812 -4.0198 35.4054
Panc 04.03 GDSC1; GDSC2; CTRP2 -1.2349 5.5876 -3.6683 17.9
PK-59 CTRP2 -1.1779 4.8858 -3.2748 18.5787
TCC-Pan2 CTRP2 -0.9823 8.9071 -5.0669 24.3229
SNU-213 CTRP2 -0.9275 1.2512 -1.353 10.3085
HPAF-II GDSC1; GDSC2; CTRP2 -0.893 2.5893 -1.9074 10.9401
PaTu 8988s CTRP2 -0.5883 2.6279 -1.6271 10.5425
PaTu 8902 GDSC1; GDSC2; CTRP2; CTRP1 -0.1541 8.3033 -1.7057 28.2506
AsPC-1 GDSC1; GDSC2; CTRP2 0.0807 3.256 -1.3154 6.8182
PaTu 8988t GDSC1; GDSC2; CTRP2 0.6192 2.6928 -0.5846 3.1872
KP-3 GDSC1; GDSC2; CTRP2; CTRP1 1.0681 5.7855 0.5204 20.3133
QGP-1 GDSC1; GDSC2; CTRP2; CTRP1 1.2289 8.2632 -0.2291 24.1057
PK-45H CTRP2 2.1655 4.6416 -0.5125 1.4043
KP-2 GDSC1; GDSC2; CTRP2 3.0088 9.7207 -2.3246 6.3107
Panc 05.04 CTRP2 5.2111 21.2056 -6.3347 17.1073
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 0.4248 5.676 -2.2318 10.8948
G-mel GDSC1; GDSC2 -9.016 -3.5007 -9.0526 75.1759
A2058 GDSC1; GDSC2 -8.0964 -2.9655 -8.634 37.6199
IST-MEL1 GDSC1; GDSC2 -7.7563 -5.4357 -7.7876 33.4908
WM278 GDSC1; GDSC2 -7.7254 -4.8759 -7.8096 33.453
DJM-1 GDSC1; GDSC2 -7.5622 -2.5637 -7.5999 68.0034
LOX-IMVI GDSC1; GDSC2; CTRP2 -7.4769 -1.1107 -7.8385 46.6258
CHL-1 GDSC1; GDSC2 -7.094 -2.3138 -7.7521 30.8474
SK-MEL-24 GDSC1; GDSC2; CTRP2 -7.0429 -1.6284 -7.2742 44.0885
WM35 GDSC1; GDSC2 -6.6114 -3.3587 -6.9018 25.8906
A-431 GDSC1; GDSC2 -6.4972 -0.4574 -6.6475 61.2597
M14 GDSC1; GDSC2 -6.4097 -2.8348 -6.8363 24.9261
A-388 GDSC1; GDSC2 -6.1881 -2.4844 -6.2001 60.5497
MZ-MEL-2 GDSC1; GDSC2 -6.1673 0.6968 -6.4534 58.9863
CJM [Human melanoma] CTRP2 -6.0409 -1.7491 -6.1817 43.2467
HMV-II GDSC1; GDSC2 -5.9229 0.5487 -7.698 26.6654
COLO 679 GDSC1; GDSC2 -5.866 -2.677 -6.2978 20.8856
A-375 GDSC1; GDSC2; CTRP2; CTRP1 -5.8161 1.3321 -6.1864 46.2229
RPMI-7951 GDSC1; GDSC2; CTRP2 -5.6257 -1.3128 -5.8019 35.8325
SK-MEL-2 GDSC1; GDSC2 -5.6202 -1.2009 -6.6126 21.4238
COLO 800 GDSC1; GDSC2; CTRP2 -5.5472 4.4779 -6.6959 49.668
IGR-37 GDSC1; GDSC2; CTRP2 -5.4275 -3.0534 -5.4375 34.2075
COLO 783 GDSC1; GDSC2 -5.2959 -1.8345 -5.3091 55.014
UACC-62 GDSC1; GDSC2; CTRP2 -4.9515 0.165 -5.3814 32.6087
Hs 944.T CTRP1 -4.1704 14.1616 -8.3474 66.7068
Hs 940.T GDSC1; GDSC2; CTRP2 -3.9937 2.1385 -4.3726 41.6251
CP50-MEL-B GDSC1; GDSC2 -3.8078 4.8966 -4.9396 46.6579
SK-MEL-5 GDSC1; GDSC2; CTRP2; CTRP1 -3.7745 0.8063 -3.9087 39.9695
WM88 CTRP2 -3.7622 1.2022 -4.3894 29.8093
SH-4 GDSC1; GDSC2 -3.7407 1.4466 -6.0636 13.8858
WM793 GDSC1; GDSC2; CTRP2 -3.6096 7.2645 -6.769 32.2013
IGR-39 CTRP2 -3.5882 0.7154 -4.0469 28.1043
WM983B CTRP2 -3.5677 1.4347 -4.2566 28.7483
Hs 938.T GDSC1; GDSC2 -3.5327 5.9129 -4.9976 45.551
HT-144 GDSC1; GDSC2; CTRP2 -3.5128 3.0683 -4.8168 26.9385
MZ-MEL-7 GDSC1; GDSC2 -3.459 2.4056 -3.8497 44.0346
COLO 792 GDSC1; GDSC2 -3.3052 3.9157 -6.9268 16.6532
Hs 294T CTRP2 -3.167 2.463 -4.2082 27.3462
GAK GDSC1; GDSC2 -3.1147 0.3741 -5.0002 7.5262
WM1552C GDSC1; GDSC2 -3.0652 0.9564 -5.2511 8.6076
G-361 GDSC1; GDSC2; CTRP2; CTRP1 -3.0091 2.6144 -3.2075 38.0739
COLO 829 GDSC1; GDSC2; CTRP2 -2.7781 6.258 -5.4785 26.9883
WT2-iPS GDSC1; GDSC2; CTRP2 -2.6432 7.3791 -4.6152 34.3599
WM115 GDSC1; GDSC2 -2.6011 5.5031 -7.1491 16.0458
Mel Ho GDSC1; GDSC2; CTRP2 -2.5932 2.9303 -3.0308 34.2097
SK-MEL-3 GDSC1; GDSC2; CTRP2 -2.0752 1.9306 -2.2549 30.662
SK-MEL-30 GDSC1; GDSC2; CTRP2 -1.8406 3.157 -2.2679 30.0504
RVH-421 GDSC1; GDSC2; CTRP2 -1.7185 2.3404 -1.9453 28.8087
451Lu GDSC1; GDSC2 -1.666 5.1647 -2.7165 34.8893
IPC-298 GDSC1; GDSC2; CTRP2 -1.5359 4.2743 -2.2672 29.2227
MMAc-SF GDSC1; GDSC2 -1.4884 7.7137 -3.5453 36.1798
COLO 741 CTRP2; CTRP1 -1.4451 1.753 -1.4749 33.7116
K029AX CTRP2 -1.3801 4.4627 -3.2659 19.0384
IGR-1 GDSC1; GDSC2; CTRP2 -1.3039 9.2263 -5.5154 23.8053
Malme-3M CTRP2 -0.5298 5.93 -3.1863 16.735
WM1799 CTRP2 -0.4895 11.8076 -6.0746 26.0531
HMCB CTRP2 -0.4094 4.0581 -2.1531 12.3009
MDA-MB-435S CTRP2 -0.4034 4.8064 -2.5166 13.7806
WM266-4 CTRP2 -0.3077 49.3782 -24.6955 42.6148
Hs 852.T CTRP2; CTRP1 -0.1695 4.1411 -0.4073 27.8019
SK-MEL-31 GDSC1; GDSC2; CTRP2 -0.0491 8.1993 -2.2863 25.5718
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 -0.0045 9.7045 -4.6074 18.5819
Mel JuSo GDSC1; GDSC2; CTRP2 0.0732 10.2368 -4.8074 19.0586
A101D GDSC1; GDSC2; CTRP2 0.0807 11.9843 -5.6744 21.5621
LB373-MEL-D GDSC1; GDSC2 0.4228 8.1946 -1.8123 26.1785
CP66-MEL GDSC1; GDSC2 0.4432 9.0767 -2.2036 27.3029
MeWo GDSC1; GDSC2; CTRP2 0.766 7.5873 -2.9082 11.4947
VMRC-MELG GDSC1; GDSC2 0.8402 5.7711 -0.2997 19.9244
Hs 688(A).T CTRP2 1.0331 4.5247 -1.1775 5.4007
UACC-257 GDSC1; GDSC2; CTRP2 1.2461 7.6407 -2.5573 9.4741
SK-MEL-28 GDSC1; GDSC2; CTRP2; CTRP1 1.5084 2.0424 1.5081 10.1345
LB2518-MEL GDSC1; GDSC2 1.6787 8.5286 -0.7518 19.5271
Hs 895.T CTRP2 1.7106 5.8688 -1.3515 5.0844
Hs 839.T CTRP2 1.9837 6.6345 -1.5341 5.4329
Hs 936.T CTRP2; CTRP1 2.0647 14.7134 -2.3637 27.6162
EquiPSC Line K2 GDSC1; GDSC2 -1.0676 8.4535 -3.4334 34.6502
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCE-4 GDSC1; GDSC2 -8.409 -4.4927 -8.4139 73.8005
KYSE-220 GDSC1; GDSC2 -6.3765 -3.4092 -6.632 23.9908
ESO-26 GDSC1; GDSC2 -5.919 -3.0726 -6.228 20.7751
OACP4 C GDSC1; GDSC2 -4.4175 1.3533 -6.6253 18.0611
ESO-51 GDSC1; GDSC2 -3.9119 -1.0156 -4.9974 9.3425
FLO-1 GDSC1; GDSC2 -3.8784 0.6533 -5.7904 12.9619
KYSE-50 GDSC1; GDSC2 -3.3408 0.432 -5.2146 9.0229
TE-12 GDSC1; GDSC2 -2.9048 4.689 -3.8905 41.7745
SK-GT-4 GDSC1; GDSC2 -2.7373 1.5113 -5.2703 8.0419
KYAE-1 GDSC1; GDSC2 -2.462 2.5727 -5.5869 8.9835
OACM5.1 C GDSC1; GDSC2 -0.5319 6.8415 -6.3089 8.9202
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 -2.977 6.3216 -5.7046 28.0782
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-32 CTRP2 -12.0319 -10.7946 -12.0319 82.9577
SK-N-MC-IXC GDSC1; GDSC2 -10.5984 -7.1887 -10.5988 86.16
NB69 GDSC1; GDSC2 -9.5854 -7.0569 -9.5954 47.1583
MHH-NB-11 GDSC1; GDSC2; CTRP2 -9.5153 -6.9756 -9.5153 71.6518
SJNB-10 GDSC1; GDSC2 -9.2219 -6.2679 -9.2549 44.4878
KP-N-SI9s CTRP2 -9.1739 0.4008 -10.0524 59.5582
SJNB-14 GDSC1; GDSC2 -9.1559 -6.3378 -9.1827 43.9801
GOTO GDSC1; GDSC2 -9.0551 -4.7961 -9.2467 43.5946
SK-N-SH GDSC1; GDSC2; CTRP2 -8.8381 -1.5571 -9.2251 53.6426
NH-12 GDSC1; GDSC2 -8.5542 -5.1838 -8.6523 39.6939
IMR-5 GDSC1; GDSC2 -8.5059 -5.6829 -8.5506 39.1675
CHP-134 GDSC2 -8.4806 -6.8886 -8.5873 18.9868
SJNB-17 GDSC1; GDSC2 -8.274 -4.2655 -8.2803 72.9407
CHP-212 GDSC1; GDSC2; CTRP2 -8.0371 -2.8362 -8.1686 49.565
SiMa GDSC1; GDSC2; CTRP2 -7.8783 -5.7941 -7.8786 48.6058
CHP-126 GDSC1; GDSC2 -7.3539 -0.8135 -7.5143 65.4777
Kelly GDSC1; GDSC2 -7.2665 -4.7931 -7.3323 29.9368
SK-N-BE(2)-M17 GDSC1; GDSC2 -7.2134 -2.4519 -7.8347 31.5809
NB1 GDSC1 -6.1508 -2.3007 -6.7379 34.3988
TGW GDSC1; GDSC2 -6.0522 -0.3316 -7.435 26.0982
SK-N-BE(2) CTRP2 -5.8126 1.2002 -6.6191 42.9429
SJNB-13 GDSC1; GDSC2 -5.7754 1.9423 -8.2006 27.9538
GI-ME-N GDSC1; GDSC2 -5.4818 1.5053 -7.7082 25.3587
SJNB-5 GDSC1; GDSC2 -4.9668 9.6227 -7.9788 51.5786
SJNB-12 GDSC1; GDSC2 -4.6628 1.608 -6.9774 20.1969
SJNB-7 GDSC1; GDSC2 -4.0124 2.8763 -7.0137 18.6756
KP-N-RT-BM-1 GDSC2 -3.6564 6.4787 -5.3401 59.7597
KP-N-YS GDSC1; GDSC2 -3.3525 4.0676 -4.1786 46.4902
SK-N-AS GDSC1; GDSC2; CTRP2 -2.8935 3.1148 -4.1863 23.4057
LA-N-6 GDSC1; GDSC2 -2.8137 4.7945 -3.8271 41.3186
SK-N-FI GDSC1; GDSC2; CTRP2 -2.2282 4.3445 -4.0469 21.3562
SK-N-DZ GDSC1; GDSC2 0.4082 12.2932 -8.2821 14.8399
NB(TU)1 GDSC1; GDSC2 0.5364 11.2209 -7.6839 12.5946
KP-N-YN GDSC1; CTRP2 3.1641 5.0064 -0.2177 0.1987
SJNB-6 GDSC1; GDSC2 3.2672 5.7498 2.0621 5.1835
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 -5.1121 -2.2 -5.1535 36.8528
SNU-1196 CTRP2 -4.5546 -0.8879 -4.7198 33.5303
SNU-869 CTRP2 -4.2236 1.7105 -5.0618 33.4108
HuCC-T1 GDSC1; GDSC2; CTRP2 -2.4337 4.2885 -4.2281 22.4255
SNU-245 CTRP2 -1.0815 1.8071 -1.7468 12.267
HuH-28 CTRP2 -1.0424 4.8516 -3.1299 17.6933
SNU-308 CTRP2 -0.664 5.7411 -3.2145 17.1452
SNU-1079 CTRP2 -0.5633 3.3871 -1.9681 11.8865
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 GDSC1; GDSC2; CTRP2 -8.8041 -5.4943 -8.8108 54.0256
HCC1806 GDSC1; GDSC2; CTRP2 -7.8705 -3.4172 -7.9386 48.6029
HCC1599 GDSC1; GDSC2 -7.6121 3.4677 -8.6508 62.7001
MDA-MB-468 GDSC1; GDSC2 -7.5545 -3.6648 -7.8521 32.9423
CAL-148 GDSC2; CTRP2 -7.1091 -3.8427 -7.1283 44.1197
SK-BR-3 CTRP2 -6.8487 -3.2974 -6.8853 48.3671
HCC38 GDSC1; GDSC2; CTRP2 -6.1257 -0.1138 -6.5916 39.3727
MDA-MB-157 GDSC1; GDSC2; CTRP2 -5.8711 -0.2523 -6.2806 37.8189
AU565 GDSC1; GDSC2; CTRP2 -5.6472 -0.6007 -5.9583 36.3044
HCC2157 GDSC1 -5.499 -0.1204 -6.9674 31.9271
MDA-MB-436 GDSC1; GDSC2 -5.2797 -0.1315 -6.7429 20.9469
Evsa-T GDSC1; GDSC2 -4.8404 1.0496 -6.8737 20.2486
CAL-51 GDSC1; GDSC2; CTRP2 -4.6636 1.6184 -5.5065 32.0888
HCC1500 GDSC1; GDSC2; CTRP2 -4.4681 3.3211 -5.9282 32.5992
MDA-MB-453 GDSC1; GDSC2; CTRP2 -4.442 0.2862 -4.8574 29.6142
CAL-85-1 GDSC1; GDSC2 -4.317 2.0002 -6.8518 18.7667
MDA-MB-175-VII GDSC1; GDSC2 -4.0531 0.4263 -5.8355 13.5994
BT-549 GDSC1; GDSC2; CTRP2 -4.0232 0.7856 -4.5422 27.4887
HCC1143 GDSC1; GDSC2; CTRP2 -3.982 -0.0527 -4.2698 26.5415
HCC70 GDSC1; GDSC2 -3.5968 0.9244 -5.6782 11.7752
HCC2218 GDSC1; GDSC2 -2.7482 3.2448 -3.2816 40.0764
HCC1569 GDSC1; GDSC2; CTRP2 -2.7456 2.131 -3.0167 34.625
BT-20 GDSC1; GDSC2; CTRP2 -2.4035 2.5025 -3.4182 19.6774
EFM-19 GDSC1; GDSC2 -2.3291 7.3167 -7.8382 18.123
T-47D GDSC1; GDSC2; CTRP2 -2.2313 5.7102 -4.6847 23.3925
MFM-223 GDSC1; GDSC2 -1.8732 6.1774 -6.925 13.7081
HCC1419 GDSC1; GDSC2; CTRP2 -1.7866 -0.0176 -1.8892 13.0569
Hs 578T GDSC1; GDSC2 -1.5788 9.3847 -8.2875 18.2375
HCC1395 GDSC1; GDSC2; CTRP2 -1.5445 7.4629 -4.8709 22.4408
BT-483 GDSC1; GDSC2 -1.3006 5.2939 -6.0839 9.1704
HCC1954 GDSC1; GDSC2; CTRP2 -1.2802 1.9863 -2.0295 12.2445
OCUB-M GDSC1; GDSC2 -1.2079 8.4316 -7.5435 14.9082
HCC1187 GDSC1; GDSC2 -1.1502 9.2335 -7.8945 16.0864
MDA-MB-415 GDSC1; GDSC2; CTRP2 -0.9595 4.4538 -2.859 14.4941
UACC-893 GDSC1; GDSC2 -0.8917 5.0725 -1.8502 30.0119
HCC1937 GDSC1; GDSC2; CTRP2 -0.8033 4.1453 -2.5621 13.1078
COLO 824 GDSC1; GDSC2 -0.6561 4.8776 -5.4705 5.6124
MRK-nu-1 GDSC1; GDSC2 -0.5566 9.628 -7.6622 14.2279
HCC1428 GDSC1; GDSC2; CTRP2 -0.4506 2.6266 -1.4939 8.5106
ZR-75-1 CTRP2 -0.2735 20.9504 -10.4558 33.7515
UACC-812 GDSC2 -0.2698 8.4437 -9.7714 6.6285
YMB-1-E GDSC2 -0.1261 11.7429 -4.0205 43.3984
HDQ-P1 GDSC1; GDSC2; CTRP2 0.6902 11.3574 -4.8534 18.108
CAL-120 GDSC1; GDSC2; CTRP2 0.8748 2.7515 -0.4241 2.2335
HMC-1-8 CTRP2 0.9149 9.2108 -3.599 15.3584
MDA-MB-231 GDSC1; GDSC2; CTRP2 0.9383 4.3806 -1.1773 4.8912
MDA-MB-330 GDSC1; GDSC2 1.0196 7.8004 -1.039 22.1142
EFM-192A GDSC1; GDSC2; CTRP2 1.0376 7.158 -2.4789 9.5115
Hs 578Bst CTRP2 1.2008 5.6343 -1.5995 6.8768
KPL-1 CTRP2 1.4136 3.7273 -0.532 2.2387
ZR-75-30 GDSC1; GDSC2; CTRP2 1.7268 3.9204 -0.4351 1.3541
MCF-7 GDSC1; GDSC2; CTRP2; CTRP1 1.9106 13.8642 -5.134 16.9585
BT-474 GDSC1; GDSC2; CTRP2 1.9709 3.2957 -0.0605 0.2443
HCC202 GDSC1; CTRP2 2.7702 4.6416 -0.2372 0.3336
CAMA-1 GDSC1; GDSC2; CTRP2 3.663 16.1817 -4.9813 14.0124
MDA-MB-361 GDSC1; GDSC2; CTRP2 4.9377 21.2046 -6.5232 16.5124
JIMT-1 GDSC1; GDSC2; CTRP2 7.4158 20.5937 -4.6411 8.8782
BT164 CTRP2 -9.8244 -9.2432 -9.8244 68.2355
BT 112 CTRP2 -9.6627 12.9326 -15.4369 55.9476
BT 416 CTRP2 -8.9218 -7.4469 -8.9218 62.198
BT 428 CTRP2 -7.3106 -1.0429 -7.6719 51.2304
BT 239 CTRP2 -4.9836 0.2711 -5.4444 37.1884
BT 245 CTRP2 -4.103 4.8682 -6.1903 35.8095
BT 172 CTRP2 -1.7812 4.737 -3.7862 21.9961
BT 187 CTRP2 -1.6249 8.4279 -5.4173 26.882
BT 228 CTRP2 -1.455 5.3398 -3.7574 21.0674
BT 330 CTRP2 -0.8913 8.2629 -4.6661 22.8565
BT 271 CTRP2 -0.8088 11.1903 -6.0461 26.6763
BT 333 CTRP2 -0.7435 8.2459 -4.5253 22.0581
BT 216 CTRP2 -0.6037 7.57 -4.0654 20.1702
BT147 CTRP2 -0.5652 5.7049 -3.1069 16.5036
BT 286 CTRP2 0.2981 20.1707 -9.5847 31.5148
BT 248 CTRP2 0.4143 19.5213 -9.1631 30.6438
BT 504 CTRP2 0.4882 11.8299 -5.2561 21.7468
BT 482 CTRP2 0.7958 9.1653 -3.6722 15.854
BT 320 CTRP2 0.9298 2.1185 -0.0863 1.1152
BT 131 CTRP2 0.9329 15.2759 -6.6134 24.5653
BT 232 CTRP2 1.021 14.7126 -6.2604 23.5141
BT 422 CTRP2 1.2613 3.085 -0.329 1.6462
BT 139 CTRP2 1.4456 12.2666 -4.7013 18.205
BT 179 CTRP2 1.7729 3.6905 -0.3105 1.0756
BT 498 CTRP2 2.0636 3.3178 -0.0319 0.1944
BT 444 CTRP2 2.2597 3.5971 -0.0571 0.181
BT 440 CTRP2 2.5759 8.7483 -2.1472 7.0342
BT 359 CTRP2 2.6179 10.7458 -3.0782 10.5399
BT 224 CTRP2 2.8622 11.1129 -3.0864 10.2104
BT 328 CTRP2 3.405 10.3738 -2.3784 6.8371
BT 231 CTRP2 3.7004 14.4769 -4.1312 12.6931
BT 159 CTRP2 4.0934 12.3666 -2.875 7.8032
BT 340 CTRP2 4.4607 17.8407 -5.2292 15.0746
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 -2.2033 1.2536 -2.7186 19.1261
Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MOG-G-UVW GDSC1; GDSC2 -9.2384 -7.0929 -9.243 44.5419
H4 GDSC1; GDSC2 -9.0399 -5.6179 -9.1172 43.2386
D-566MG GDSC1; GDSC2 -8.8764 -3.9283 -8.8963 75.2176
8-MG-BA GDSC1; GDSC2 -8.7623 -5.8489 -8.8055 41.0823
D283 Med GDSC1; GDSC2 -8.121 -4.4261 -8.3044 36.7463
D-423MG GDSC1; GDSC2 -8.1154 -3.3125 -8.1386 71.2813
GI-1 GDSC1; GDSC2 -7.9681 -4.0435 -8.2152 35.824
AM-38 GDSC1; GDSC2 -7.2952 -3.079 -7.7268 31.5069
42-MG-BA GDSC1; GDSC2; CTRP2 -7.1846 -3.3844 -7.2277 44.6057
M059J GDSC1; GDSC2 -7.0496 -3.3884 -7.372 29.2866
SF268 GDSC1; GDSC2; CTRP2 -7.0312 -2.8025 -7.1114 43.7793
SF539 GDSC1; GDSC2; CTRP2 -6.9687 -4.24 -6.9754 43.2677
ONS-76 GDSC1; GDSC2; CTRP2 -6.7589 -1.3761 -7.0114 42.5217
SK-MG-1 GDSC1; GDSC2 -6.701 -3.1123 -7.0689 26.8653
Daoy GDSC1; GDSC2; CTRP2 -6.6698 -0.9341 -6.999 42.1535
D-263MG GDSC1; GDSC2 -6.0611 -0.2725 -7.47 26.2593
YH-13 GDSC1; GDSC2 -5.8087 -0.8633 -6.9528 23.4234
GB-1 GDSC1; GDSC2; CTRP2 -5.7694 0.032 -6.2395 37.382
Becker GDSC1; GDSC2 -5.6698 -2.8759 -6.0185 19.0706
D-392MG GDSC1; GDSC2 -5.6599 0.3683 -7.3521 24.5526
SF295 GDSC1; GDSC2; CTRP2; CTRP1 -5.6524 -0.7493 -5.6865 54.7852
PFSK-1 GDSC1 -5.6414 1.5494 -7.8845 35.8886
D-336MG GDSC1; GDSC2 -5.5715 0.9366 -5.8519 55.9213
MOG-G-CCM GDSC1; GDSC2 -5.4775 1.5145 -7.7084 25.3466
LNZTA3WT4 GDSC1; GDSC2 -4.9039 0.983 -6.9021 20.5424
Hs 683 GDSC1; GDSC2; CTRP2 -4.7241 2.0571 -5.1487 45.4925
U-251MG GDSC1; GDSC2; CTRP2 -4.6716 2.4092 -5.7955 32.8621
D-245MG GDSC2 -4.5971 7.9651 -6.9175 61.8685
Onda 10 GDSC1; GDSC2 -4.4235 3.7356 -5.2473 49.6169
KNS-81-FD GDSC1; GDSC2 -4.4154 15.787 -10.1317 49.783
SNB-75 GDSC1; GDSC2; CTRP2 -4.3271 1.9895 -4.7033 43.3787
U-118MG GDSC1; GDSC2; CTRP2 -4.3067 4.112 -6.0806 32.509
SNU-626 CTRP2 -4.2116 0.5433 -4.6767 32.2165
SNU-738 CTRP2 -3.5808 -0.31 -3.7757 27.1462
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 -3.1525 6.2965 -7.9907 20.4169
SF126 GDSC1; GDSC2; CTRP2 -3.1184 5.4057 -4.3686 38.6581
LN-18 GDSC1; GDSC2; CTRP2 -2.6123 1.7255 -3.3318 19.906
KINGS-1 GDSC1; GDSC2 -2.5693 2.4041 -5.5845 9.176
D-247MG GDSC1; GDSC2 -2.5475 9.9385 -5.6027 42.5977
M059K CTRP2 -1.9936 3.7322 -3.5322 21.619
DK-MG GDSC1; GDSC2; CTRP2 -1.5852 4.6302 -3.5445 18.2238
GMS-10 CTRP2 -1.4076 2.9224 -2.5747 16.4011
D-502MG GDSC1; GDSC2 -1.3986 13.7167 -6.1909 39.93
DBTRG-05MG GDSC1; GDSC2; CTRP2 -1.2841 9.6005 -5.6821 24.2226
CAS-1 GDSC1; GDSC2; CTRP2 -1.2051 7.1352 -4.3959 20.2492
KG-1-C CTRP2 -1.1353 3.8792 -2.7515 16.424
SNU-466 CTRP2 -1.1352 0.863 -1.4272 11.1781
LN-405 GDSC1; GDSC2 -0.7523 7.4719 -6.7566 11.0802
SW1088 GDSC1; GDSC2; CTRP2 -0.7268 11.0516 -5.905 23.7037
GaMG GDSC1; GDSC2; CTRP2; CTRP1 -0.317 7.9502 -1.7419 28.6766
TM-31 CTRP2 -0.1288 6.9946 -3.3612 16.5411
KNS-42 GDSC1; GDSC2; CTRP2 0.2073 9.7246 -2.7393 26.2256
KALS-1 GDSC1; GDSC2; CTRP2 0.2474 13.1701 -6.1269 22.4694
NMC-G1 GDSC1; GDSC2; CTRP2 0.4524 11.1719 -3.192 26.8506
A-172 GDSC1; GDSC2; CTRP2 0.7634 13.0015 -5.6152 20.1953
GOS-3 CTRP2 0.9151 10.0581 -4.0217 16.8883
SNU-489 CTRP2 0.9263 5.8434 -1.9119 8.6395
YKG-1 GDSC1; GDSC2; CTRP2 1.0097 5.354 0.0545 15.9042
CCF-STTG1 CTRP2 1.3683 3.425 -0.4202 1.8663
LN-229 GDSC1; GDSC2; CTRP2; CTRP1 1.5092 8.452 -2.759 9.8011
T98G GDSC1; GDSC2; CTRP2 1.5253 7.5445 -2.2995 8.132
SNU-201 CTRP2 1.6374 6.6538 -1.7819 6.9342
SW1783 GDSC1; GDSC2; CTRP2 1.8079 7.0728 -1.8652 6.1817
D-542MG GDSC1; GDSC2 1.9289 9.0086 -0.7519 18.9603
SNU-1105 CTRP2 2.1715 3.2606 0.0283 0.0879
Onda 11 GDSC1; GDSC2 2.3371 20.4369 -6.0695 31.531
U-87MG ATCC GDSC1; GDSC2; CTRP2 3.3801 14.599 -4.4121 12.6858
⏷ Show the Full List of 67 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1; GDSC2 -4.7073 -0.1311 -6.1803 16.8783
TGBC24TKB GDSC1; GDSC2 -4.0792 -1.4808 -4.9305 9.4675
TGBC1TKB GDSC1; GDSC2 -3.2032 2.5477 -6.1584 13.0953
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC1; GDSC2; CTRP2 -9.143 -7.372 -9.143 56.0498
JHUEM-2 CTRP2; CTRP1 -8.8085 -4.2512 -8.8574 60.7707
MFE-296 GDSC1; GDSC2; CTRP2 -6.8764 -3.4491 -6.9059 42.7772
JHUEM-3 CTRP2 -5.2613 -1.0292 -5.4571 38.2876
JHUEM-7 CTRP2 -4.9549 -0.2369 -5.2862 36.6574
MFE-280 GDSC1; GDSC2 -4.4826 -0.4828 -5.7957 14.5317
HEC-50B CTRP2 -3.9548 -0.5116 -4.1406 29.6083
KLE GDSC1; GDSC2; CTRP2; CTRP1 -3.5901 2.1051 -3.7584 40.6451
HEC-151 CTRP2; CTRP1 -3.0756 0.0191 -3.2994 23.8759
JHUEM-1 CTRP2 -2.9193 2.7003 -4.0416 26.0377
HEC-6 CTRP2; CTRP1 -2.8569 -0.7293 -2.8574 40.7744
RL95-2 GDSC1; GDSC2; CTRP2 -2.5446 2.1995 -3.4437 20.1087
HEC-108 CTRP2; CTRP1 -2.1447 1.5837 -2.1886 37.2792
HEC-265 CTRP2; CTRP1 -1.7667 -0.3282 -1.7667 35.2624
HEC-251 CTRP2; CTRP1 -1.4431 2.1783 -1.5003 33.7696
MFE-319 GDSC1; GDSC2; CTRP2; CTRP1 -0.6062 8.1064 -2.1106 30.109
EFE-184 CTRP2 -0.3513 3.1312 -1.645 10.0647
HEC-1-A CTRP2 0.2351 5.7386 -2.422 12.0526
HEC-59 CTRP2; CTRP1 0.3089 5.6569 -0.2673 26.2861
AN3-CA GDSC1; GDSC2; CTRP2 0.739 9.4466 -3.8588 14.8427
HEC-1-B CTRP2 1.2312 5.7181 -1.6182 6.9044
EN GDSC1; GDSC2; CTRP2 2.2732 3.5173 -0.0239 0.1154
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 -3.9051 1.0572 -3.9835 46.1705
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-195 GDSC1; GDSC2 -8.3341 -5.6262 -8.3756 37.8685
SW13 GDSC1; GDSC2 -8.3116 -6.052 -8.3275 37.6108
KTCTL-140 GDSC1; GDSC2 -7.8448 -1.8128 -7.9372 68.5412
LB996-RCC GDSC1; GDSC2 -7.7746 -5.2267 -7.887 28.5641
BB65-RCC GDSC1; GDSC2 -7.7436 3.3299 -8.7564 63.2214
LB2241-RCC GDSC1; GDSC2 -7.561 -4.3041 -7.5629 69.1989
SN12C GDSC1; GDSC2 -6.7657 -4.2356 -6.8759 26.3413
HA7-RCC GDSC1; GDSC2 -6.6399 -2.0529 -6.6749 62.9412
KTCTL-13 GDSC1; GDSC2 -6.3426 -2.3042 -6.3617 61.3941
KTCTL-21 GDSC1; GDSC2 -6.1039 -1.6104 -6.1442 59.7716
SW156 GDSC1; GDSC2 -6.0981 3.6121 -7.0391 57.2025
A-498 GDSC1; GDSC2; CTRP2 -5.3056 0.3229 -5.8096 34.8352
RXF 393L GDSC1; GDSC2 -4.849 5.3415 -6.2184 51.5336
A-704 GDSC1; GDSC2 -4.7328 0.8681 -6.6839 19.1519
UO-31 GDSC1; GDSC2; CTRP2 -4.388 0.4004 -4.5112 43.318
ACHN GDSC1; GDSC2; CTRP2 -4.2505 1.0979 -4.8866 29.1546
CAL-54 GDSC1; GDSC2; CTRP2 -4.2333 1.7746 -5.0947 29.7095
TK-10 GDSC1; GDSC2 -4.1619 -0.2915 -5.5836 12.7119
LB1047-RCC GDSC1; GDSC2 -4.1445 3.7565 -4.9491 48.1916
KTCTL-26A GDSC1; GDSC2 -4.1037 2.527 -4.5795 47.8205
KTCTL-1M GDSC1; GDSC2 -3.5822 3.6788 -4.3131 45.1488
BFTC-909 GDSC1; GDSC2; CTRP2 -3.2002 2.4675 -4.2451 24.368
KMRC-20 GDSC1; GDSC2; CTRP2 -3.1698 2.2864 -4.1419 23.9624
786-O GDSC1; GDSC2; CTRP2 -2.4943 5.1166 -4.6674 23.9512
NCC010 GDSC1; GDSC2 -2.4456 5.1465 -3.5505 39.4484
KMRC-3 CTRP2 -2.0586 2.9055 -3.2308 20.6623
VMRC-RCW GDSC1; GDSC2; CTRP2; CTRP1 -1.6871 6.3007 -2.6409 36.9055
TUHR10TKB CTRP2 -1.1927 1.2389 -1.6292 12.1105
769-P GDSC1; GDSC2; CTRP2 -0.91 2.3734 -1.8248 10.6831
TUHR14TKB CTRP2 -0.4025 24.2772 -12.2278 44.0012
Caki-1 GDSC1; GDSC2; CTRP2 -0.3048 5.1056 -1.2342 23.0639
NCC021 GDSC1; GDSC2 -0.151 12.6512 -4.4793 34.1982
VMRC-RCZ GDSC1; GDSC2; CTRP2 0.0709 5.9828 -2.6839 11.8779
KMRC-1 GDSC1; GDSC2; CTRP2 0.1918 7.1508 -3.1644 13.3884
TUHR4TKB CTRP2 0.422 6.0546 -2.4234 11.6896
OS-RC-2 GDSC1; GDSC2; CTRP2 0.4267 7.934 -3.3591 13.6631
KMRC-2 CTRP2 0.5538 3.507 -1.0421 5.6633
RCC10RGB GDSC1; GDSC2; CTRP2; CTRP1 0.791 10.615 -4.4002 16.5257
SNU-1272 CTRP2 1.3063 3.6804 -0.5781 2.5528
Caki-2 CTRP2 2.3661 3.5134 0.0108 0.0767
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 63 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-CO-1 GDSC1; GDSC2; CTRP2; CTRP1 -8.5147 -3.51 -8.5257 62.6327
SW48 GDSC1; GDSC2; CTRP2; CTRP1 -7.427 -3.5543 -7.4298 57.8791
CaR-1 GDSC1; GDSC2 -6.9317 -3.4907 -7.2166 28.264
SNU-175 GDSC2; CTRP1 -6.7971 -1.1155 -7.1207 42.2977
CL-34 CTRP1 -6.5431 1.3118 -7.4887 69.9751
SNU-C5 GDSC1; GDSC2; CTRP2; CTRP1 -5.7066 0.7444 -6.3658 37.4538
HCT 116 GDSC1; GDSC2; CTRP2; CTRP1 -5.6857 -0.3694 -6.0513 36.6599
GP5d GDSC1; GDSC2 -5.6653 0.2 -7.2805 24.2901
LS513 GDSC1; GDSC2; CTRP2; CTRP1 -5.3156 0.4864 -5.4119 48.2953
SNU-1033 CTRP2 -5.2309 3.71 -6.8914 41.0201
LoVo GDSC1; GDSC2; CTRP2; CTRP1 -5.1539 0.1206 -5.5907 33.7927
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2; CTRP1 -4.8363 -1.1361 -4.9821 31.1275
CCK-81 GDSC1; GDSC2 -4.7577 -1.9665 -5.3907 13.4807
SNU-C2B GDSC1; GDSC2 -4.6883 0.7829 -6.6005 18.6728
SW620 GDSC1; GDSC2; CTRP2; CTRP1 -4.587 3.4924 -5.3565 41.0247
RKO GDSC1; GDSC2; CTRP2; CTRP1 -4.5258 1.2576 -5.2372 30.9488
LS180 GDSC1; GDSC2; CTRP2; CTRP1 -4.5032 2.4086 -5.6144 31.9048
HCC2998 GDSC1; GDSC2 -4.5018 2.6996 -7.3648 21.3294
DiFi GDSC1; GDSC2 -4.3205 0.6319 -6.1823 15.8564
SNU-81 GDSC1; GDSC2; CTRP2; CTRP1 -4.3059 9.3926 -7.1907 45.4705
SW626 GDSC1; GDSC2 -4.2929 0.1876 -5.9396 14.6861
COLO 320HSR GDSC1; GDSC2 -4.2181 0.2558 -5.9033 14.3276
HCT 15 GDSC1; GDSC2; CTRP2 -4.1308 1.1965 -4.7881 28.5277
SNU-1040 GDSC1; CTRP1 -3.9746 1.1332 -4.6396 35.7076
GP2d CTRP2; CTRP1 -3.7949 2.1157 -3.9779 45.7398
CW-2 GDSC1; GDSC2; CTRP2; CTRP1 -3.629 3.5348 -5.1309 28.1615
SNU-C1 GDSC1; GDSC2; CTRP2 -3.5539 0.2776 -3.8859 24.1668
NCI-H508 GDSC1; GDSC2; CTRP2; CTRP1 -3.5446 3.1783 -4.1329 39.633
KM12 GDSC1; GDSC2; CTRP2; CTRP1 -3.2183 1.042 -3.7461 22.821
SW837 GDSC1; GDSC2 -3.1923 4.8239 -7.2874 17.8634
SNU-407 GDSC1; GDSC2; CTRP2 -3.123 4.5554 -5.0471 26.6165
SW1417 GDSC1; GDSC2; CTRP2 -2.9799 0.8829 -3.4359 21.1945
CL-11 GDSC1; GDSC2; CTRP2 -2.9762 5.723 -5.427 27.3278
COLO201 CTRP2 -2.9634 -0.9095 -3.0144 22.5229
SW1463 GDSC1; GDSC2 -2.8249 8.9796 -9.0636 23.2053
SW1116 GDSC1; GDSC2 -2.7016 4.1971 -6.5778 13.8801
SNU-C2A CTRP2; CTRP1 -2.643 2.0822 -2.7519 39.9285
SNU-C4 CTRP2; CTRP1 -2.532 1.1187 -3.0269 21.2347
HT115 GDSC1; GDSC2; CTRP2; CTRP1 -2.4098 3.0377 -2.858 33.2346
T84 GDSC1; GDSC2; CTRP2 -2.2927 1.3338 -2.8438 17.4798
LS1034 GDSC1; GDSC2; CTRP2 -2.2273 2.2812 -3.142 18.3187
NCI-H747 GDSC1; GDSC2; CTRP2 -2.1648 3.0881 -3.4196 19.111
SNU-283 GDSC2 -2.0907 3.8966 -2.7514 53.118
SW480 CTRP1 -1.9369 3.0096 -3.225 37.5905
CL-40 CTRP1 -1.8588 8.0946 -5.5683 42.5045
SW948 GDSC1; GDSC2; CTRP2; CTRP1 -1.2299 6.1095 -3.9173 18.7324
COLO205 GDSC1; GDSC2; CTRP2; CTRP1 -1.1935 5.6511 -1.9037 30.9657
COLO 678 GDSC1; GDSC2; CTRP2; CTRP1 -0.9556 3.6955 -2.4905 13.1652
HCT 8 CTRP2; CTRP1 -0.8498 3.0353 -2.074 12.9982
LS123 GDSC1; GDSC2; CTRP2; CTRP1 -0.8277 3.6434 -2.3428 12.3666
HCC-56 CTRP2 -0.8224 9.0419 -4.9906 23.7233
DLD-1 CTRP2; CTRP1 -0.7633 1.7725 -0.7763 30.2235
LS411N GDSC1; GDSC2; CTRP2; CTRP1 -0.5381 2.3622 -0.5716 26.4201
HT-55 GDSC1; GDSC2; CTRP2; CTRP1 -0.4098 5.2095 -2.7217 12.907
C2BBe1 GDSC1; GDSC2; CTRP2; CTRP1 -0.3015 7.0284 -1.3841 27.825
COLO 320 CTRP2; CTRP1 -0.1768 6.4001 -3.1067 15.656
SNU-503 CTRP2 -0.1087 4.1512 -1.9278 10.7113
NCI-H716 GDSC1; GDSC2; CTRP2 0.1052 1.66 -0.5021 3.7688
HT-29 GDSC1; GDSC2; CTRP2; CTRP1 0.4898 2.4124 0.4237 14.3788
SW403 CTRP1 0.5242 12.245 -2.7022 55.3433
OUMS-23 CTRP2 0.8042 3.3736 -0.7808 4.1264
SNU-61 GDSC1; GDSC2; CTRP2; CTRP1 0.8293 5.7184 -1.9257 7.8146
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 1.7032 14.6844 -5.7027 18.8926
⏷ Show the Full List of 63 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 -6.9729 -0.3951 -8.3625 32.4246
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-5 CTRP2 -7.1507 -2.6347 -7.2535 50.3356
HLE GDSC1; GDSC2 -6.9922 -2.7925 -7.4835 29.4969
JHH-4 GDSC1; GDSC2; CTRP2 -5.0325 -0.7979 -5.2521 32.4901
Li-7 CTRP2 -4.9027 -0.5343 -5.1639 36.1198
SNU-398 GDSC1; GDSC2; CTRP2; CTRP1 -4.6202 4.5089 -6.5743 34.519
Hep-G2/C3A GDSC1; GDSC2 -4.5886 1.1834 -6.7012 18.8375
HuH-1 GDSC1; GDSC2; CTRP2 -4.5193 2.384 -5.6226 31.9729
HLF CTRP2 -4.4971 -0.4292 -4.7456 33.4126
Huh-7 GDSC1; GDSC2 -3.7143 4.2611 -7.4452 19.6803
JHH-1 GDSC1; GDSC2; CTRP2 -3.7015 2.4942 -4.789 27.3556
JHH-7 GDSC1; GDSC2 -3.4697 1.7382 -5.9761 12.8596
SNU-182 CTRP2 -2.6745 -0.7582 -2.7256 20.5914
SNU-878 CTRP2 -2.2444 5.209 -4.4626 25.5596
SK-HEP-1 GDSC1; GDSC2; CTRP2 -1.462 2.3362 -2.3687 13.8478
JHH-2 GDSC1; GDSC2; CTRP2 -1.3499 6.5477 -4.243 20.058
SNU-423 GDSC1; GDSC2; CTRP2 0.128 9.4915 -4.3884 17.6473
JHH-6 GDSC1; GDSC2; CTRP1 0.5869 2.4825 0.5788 21.2053
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 0.6726 7.1894 -1.1013 20.3938
PLC/PRF/5 CTRP2 1.0456 2.8612 -0.3606 2.0384
Hep-G2 CTRP2; CTRP1 1.2517 19.4833 -8.4563 27.9389
SNU-387 GDSC1; GDSC2; CTRP2 1.9427 5.0056 -0.798 2.3129
SNU-449 GDSC1; GDSC2; CTRP2; CTRP1 2.3197 8.8422 0.6491 17.5818
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 224 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1184 CTRP2 -11.6665 2.0373 -13.2543 65.889
NCI-H1876 GDSC1; GDSC2; CTRP1 -11.2077 -7.1748 -11.215 67.339
NCI-H209 GDSC1; GDSC2 -10.6588 -7.2307 -10.6868 55.0682
SBC-3 GDSC1; GDSC2 -9.8651 -5.9895 -9.9495 49.2796
Lu-134-A GDSC1; GDSC2 -9.5377 0.5931 -10.0724 71.1071
NCI-H1105 GDSC1; GDSC2; CTRP2; CTRP1 -9.4953 -2.7937 -9.5852 68.9212
NCI-H526 GDSC1; GDSC2; CTRP2 -9.3407 -8.0362 -9.3407 57.214
EBC-1 GDSC1; GDSC2; CTRP1 -9.3099 -6.4209 -9.3099 66.5233
NCI-H1048 GDSC1; GDSC2; CTRP1 -9.1733 -6.2535 -9.1733 65.8978
NCI-H1155 GDSC1; GDSC2; CTRP2 -8.7896 -6.6812 -8.7897 53.9688
COR-L311 GDSC2 -8.6267 -5.1311 -9.3495 23.8274
COR-L279 GDSC1; GDSC2; CTRP2; CTRP1 -8.6082 -5.709 -8.6083 63.3165
COLO 668 GDSC1; GDSC2; CTRP2; CTRP1 -8.5951 -5.6498 -8.5952 63.2549
NCI-H2795 GDSC1; GDSC2 -8.5356 -4.0942 -8.821 40.0732
LC-2/ad GDSC1; GDSC2 -8.5327 -4.8806 -8.5353 74.7515
NCI-H1694 GDSC1; GDSC2; CTRP2; CTRP1 -8.5222 -5.6727 -8.5249 52.3889
HCC78 GDSC1; GDSC2; CTRP2; CTRP1 -8.3117 -5.9025 -8.3117 61.969
NCI-H2286 CTRP1 -8.1597 -1.0695 -8.2606 83.0882
NCI-H1341 GDSC1; GDSC2 -8.1212 -5.1835 -8.1931 36.3768
NCI-H1734 GDSC1; GDSC2; CTRP2 -8.119 -5.0515 -8.1198 63.8564
NCI-H2081 GDSC1; GDSC2; CTRP2; CTRP1 -8.0134 -2.0805 -8.0933 62.2916
NCI-H187 GDSC1 -7.8956 -2.0026 -8.7271 50.5612
DV-90 CTRP2; CTRP1 -7.756 3.3202 -8.4727 61.552
NCI-H290 GDSC1; GDSC2 -7.7227 -2.7724 -7.756 68.949
SK-LU-1 GDSC1; GDSC2; CTRP1 -7.7144 -1.8885 -7.9692 47.3374
NCI-H2087 GDSC1; GDSC2; CTRP2 -7.6631 -1.4384 -7.9766 47.5927
Lu-99A GDSC1; GDSC2 -7.597 -4.6694 -7.7005 32.5605
HOP-62 GDSC1; GDSC2; CTRP2 -7.545 -3.5777 -7.5893 46.7049
NCI-H2227 GDSC1; GDSC2 -7.3647 -0.7118 -7.5372 65.4309
ABC-1 GDSC1; GDSC2 -7.2704 -1.5255 -7.3599 65.7366
NCI-H748 GDSC2 -7.0813 -0.1237 -7.3098 81.2645
NCI-H1781 GDSC1; GDSC2; CTRP1 -6.9569 -4.1844 -6.9656 42.6202
Lu-99 CTRP2; CTRP1 -6.9166 -1.942 -6.9379 60.9656
NCI-H2373 GDSC1; GDSC2 -6.8938 -2.2713 -7.5502 29.3892
IST-SL2 GDSC1; GDSC2 -6.692 -1.296 -6.7739 62.7653
EMC-BAC-1 GDSC1; GDSC2 -6.6391 -1.9797 -6.6774 62.8978
HCC1359 CTRP1 -6.5818 4.5639 -8.7215 65.12
HCC1438 CTRP2 -6.49 -4.6019 -6.4905 45.9366
DMS 53 GDSC1; GDSC2; CTRP2 -6.4689 -2.6677 -6.5338 40.4728
DMS 273 GDSC1; GDSC2; CTRP1 -6.4671 0.2616 -6.5994 53.3211
NCI-H1703 GDSC1; GDSC2 -6.4185 -4.2921 -6.4944 23.5963
SBC-5 GDSC1; GDSC2; CTRP2 -6.3957 -3.0276 -6.4322 39.9744
NCI-H510A GDSC1; GDSC2 -6.3932 4.3689 -7.5838 60.2328
LCLC-97TM1 GDSC1; GDSC2; CTRP2; CTRP1 -6.3079 -0.5143 -6.3739 52.6992
NCI-H3122 GDSC1; GDSC2 -6.2643 -2.6143 -6.7508 24.0847
NCI-H2810 GDSC1; GDSC2 -6.253 0.0483 -6.4496 59.7592
EMC-BAC-2 GDSC1; GDSC2 -6.1518 -1.4789 -7.0543 24.9354
NCI-H2170 GDSC1; GDSC2; CTRP2 -6.1506 -1.9074 -6.2777 38.7648
COR-L303 GDSC2 -6.1452 -0.7499 -6.247 80.8116
COR-L23 GDSC1; GDSC2; CTRP1 -6.1229 -1.5519 -6.3125 38.1347
NCI-H2591 GDSC1; GDSC2 -6.0492 -2.7023 -6.4879 22.2842
Lu-135 GDSC1; GDSC2 -5.9591 -0.347 -7.3327 25.4087
A-427 GDSC1; GDSC2 -5.9429 0.8502 -6.2373 57.8231
NCI-H838 GDSC1; GDSC2 -5.9216 3.9359 -6.9399 56.3546
NCI-H211 GDSC1; GDSC2; CTRP2 -5.883 -2.0707 -5.9746 37.1119
NCI-H2369 GDSC1; GDSC2 -5.8347 -1.1325 -6.8647 23.1448
NCI-H524 GDSC1; GDSC2; CTRP2 -5.7468 1.7658 -6.7306 38.3388
NCI-H2171 GDSC2 -5.7448 -1.3672 -5.7864 81.3406
NCI-H2804 GDSC1; GDSC2 -5.7303 0.5319 -5.9588 56.8897
KNS-62 GDSC1; GDSC2; CTRP2; CTRP1 -5.6404 -2.4587 -5.642 49.7284
RERF-LC-A1 CTRP2 -5.6363 0.0163 -6.0904 41.2861
NCI-H1568 GDSC1; GDSC2; CTRP1 -5.6353 -1.6687 -5.6442 49.7062
IST-SL1 GDSC1; GDSC2 -5.6218 3.029 -6.3602 55.4255
NCI-H292 GDSC1; GDSC2; CTRP2 -5.6077 0.0636 -5.7652 49.9039
Lu-139 GDSC1; GDSC2 -5.6008 -0.112 -7.0736 23.2708
PaCa-3 GDSC1; GDSC2 -5.5572 -1.9116 -6.2518 19.6925
SW1271 GDSC1; GDSC2 -5.5472 -1.9581 -6.2227 19.5368
SCLC-21H CTRP1 -5.5205 2.2351 -6.6952 64.2198
NCI-H23 GDSC1; GDSC2; CTRP1 -5.4528 0.0327 -5.5216 48.8966
NCI-H446 GDSC1; GDSC2 -5.4484 -1.2461 -6.4152 20.0555
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2; CTRP1 -5.4001 0.4438 -5.4969 48.6718
HOP-92 GDSC1; GDSC2; CTRP2 -5.3814 5.3666 -7.7294 38.8757
NCI-H1623 GDSC1; GDSC2; CTRP2 -5.3338 0.9213 -6.0118 35.4245
COR-L32 GDSC1; GDSC2 -5.2998 0.2622 -5.4625 54.6613
SK-MES-1 GDSC1; GDSC2; CTRP2 -5.2672 -1.2711 -5.4234 33.6834
Calu-3 GDSC1; GDSC2; CTRP2; CTRP1 -5.0986 3.0441 -5.5314 47.5217
NCI-H1651 GDSC1; GDSC2; CTRP2 -5.0899 -0.1494 -5.4539 33.227
SW1573 GDSC1; GDSC2; CTRP2 -5.0424 6.0451 -7.6696 37.78
NCI-H2073 CTRP1 -5.0345 6.2872 -7.839 58.0646
PC-14 GDSC1; GDSC2 -4.9987 0.0586 -5.1194 41.9803
DMS 79 GDSC1; GDSC2; CTRP2 -4.9903 0.2417 -5.1312 46.6114
NCI-H1666 GDSC1; GDSC2; CTRP2; CTRP1 -4.9746 2.1852 -5.249 46.904
DMS 454 CTRP2 -4.8096 0.2027 -5.2363 35.9811
NCI-H226 GDSC1; GDSC2 -4.7921 0.4652 -6.5466 18.723
LK-2 GDSC1; GDSC2 -4.7897 0.8332 -6.7212 19.466
NCI-H1648 GDSC1; GDSC2 -4.6747 -1.1369 -5.6767 14.5221
COR-L95 GDSC1; GDSC2; CTRP2 -4.5842 0.9692 -5.2096 31.0414
NCI-H596 GDSC1; GDSC2; CTRP1 -4.5185 -1.5121 -4.6025 28.3486
LUDLU-1 CTRP2 -4.4536 -0.8352 -4.62 32.8631
NCI-H146 GDSC1; GDSC2; CTRP2 -4.4489 4.6355 -5.5506 44.7905
NCI-H1581 GDSC1; GDSC2; CTRP2 -4.3964 0.3993 -4.8382 29.4271
SBC-1 GDSC1; GDSC2 -4.3539 3.0754 -4.9889 49.2344
NCI-H2110 GDSC1; GDSC2; CTRP2; CTRP1 -4.3456 0.1513 -4.44 43.0346
NCI-H2029 GDSC1; GDSC2; CTRP2; CTRP1 -4.2764 1.356 -4.4001 48.0337
NCI-H1944 GDSC1; GDSC2; CTRP2; CTRP1 -4.2746 3.3836 -4.7056 44.0291
NCI-H2731 GDSC1; GDSC2 -4.2233 0.4193 -5.9882 14.7288
NCI-H358 GDSC1; GDSC2; CTRP2; CTRP1 -4.2158 3.5432 -4.6743 43.8065
NCI-H513 GDSC1; GDSC2 -4.198 0.7798 -6.142 15.3611
NCI-H2818 GDSC1; GDSC2 -4.1695 1.9394 -6.6885 17.6982
COR-L88 GDSC1; GDSC2; CTRP1 -4.1686 1.0838 -4.2613 43.1368
NCI-H810 GDSC1; GDSC2; CTRP2; CTRP1 -4.1539 3.325 -4.5631 43.4841
NCI-H1437 GDSC1; GDSC2; CTRP1 -4.1238 1.6466 -4.2699 53.0135
NCI-H2228 GDSC1; GDSC2 -4.1172 1.2077 -6.2794 15.7745
NCI-H2405 GDSC1; GDSC2; CTRP2; CTRP1 -4.1027 1.5209 -4.2338 42.8965
CPC-N GDSC1; GDSC2 -4.0792 5.8452 -8.5509 24.4741
EPLC-272H GDSC1; GDSC2; CTRP2; CTRP1 -4.0607 0.5585 -4.1112 42.5798
COR-L51 CTRP1 -4.0393 5.7218 -6.5738 53.9805
A-549 GDSC1; GDSC2; CTRP2; CTRP1 -4.0337 1.9446 -4.21 42.6528
Ms-1 GDSC1; GDSC2 -4.0103 2.1434 -6.6475 17.126
NCI-H1963 GDSC1; GDSC2; CTRP1 -3.8944 -1.0436 -4.0001 24.7049
NCI-H661 GDSC1; GDSC2; CTRP2; CTRP1 -3.8222 8.1627 -5.5864 43.4734
HCC15 GDSC1; GDSC2; CTRP2; CTRP1 -3.8072 3.3146 -5.2272 28.9098
DMS 114 GDSC1; GDSC2; CTRP2 -3.7779 3.2898 -5.1863 28.7158
NCI-H2122 GDSC1; GDSC2; CTRP2; CTRP1 -3.7574 2.2257 -4.7464 27.3785
NCI-H2461 GDSC1; GDSC2 -3.6557 2.8994 -6.7149 16.564
NCI-H2196 GDSC2; CTRP2 -3.6347 3.574 -4.3404 40.3082
RERF-LC-MS GDSC1; GDSC2; CTRP2 -3.6124 3.4673 -4.2859 40.1381
NCI-H1650 GDSC1; GDSC2 -3.5978 -0.6273 -4.9055 8.143
NCI-H1693 GDSC1; GDSC2; CTRP2 -3.5877 3.5853 -5.1087 27.9888
NCI-H1092 GDSC1; GDSC2; CTRP2 -3.3851 3.7103 -4.95 27.0001
NCI-H1793 GDSC1; GDSC2; CTRP2; CTRP1 -3.3385 1.5235 -3.4296 39.3636
NCI-H1930 CTRP1 -3.2991 -0.1445 -3.3067 62.3332
NCI-H650 GDSC1; GDSC2; CTRP2; CTRP1 -3.2503 1.7534 -3.3586 38.9951
NCI-H460 GDSC1; GDSC2; CTRP2; CTRP1 -3.2491 4.1283 -4.0847 38.5649
Sq-1 CTRP2; CTRP1 -3.037 -0.2062 -3.2071 23.4289
NCI-H2009 GDSC1; GDSC2; CTRP2; CTRP1 -3.0304 9.0533 -5.0626 40.8021
NCI-H2347 GDSC1; GDSC2 -2.9755 2.8537 -6.126 12.4618
COR-L321 GDSC1; GDSC2 -2.8932 2.3875 -3.2305 40.5437
NCI-H520 GDSC1; GDSC2; CTRP2 -2.8166 1.8775 -3.6078 21.3324
NCI-H522 GDSC1; GDSC2; CTRP2; CTRP1 -2.7678 1.9929 -2.8743 36.7926
HCC1588 CTRP2 -2.7658 3.5428 -4.2365 26.2579
NCI-H889 CTRP2 -2.7381 2.481 -3.7615 24.5228
LC-1/sq GDSC1; GDSC2 -2.6511 5.7983 -7.3358 16.8891
NCI-H69 GDSC1; GDSC2; CTRP2 -2.6458 3.1505 -3.9437 22.0107
LB647-SCLC GDSC1; GDSC2 -2.5924 4.8766 -3.6153 40.1132
NCI-H1688 GDSC1; GDSC2 -2.5881 0.1793 -4.5051 4.2058
NCI-H250 GDSC2 -2.5416 4.0509 -3.2901 55.9947
NCI-H2141 GDSC1; GDSC2; CTRP1 -2.5119 3.7747 -4.1513 21.6037
COLO 699 CTRP2; CTRP1 -2.4791 2.4165 -3.4623 22.6933
NCI-H647 GDSC1; GDSC2; CTRP2 -2.4621 2.6591 -2.8225 33.2941
NCI-H441 GDSC1; GDSC2; CTRP2; CTRP1 -2.4025 3.5692 -3.8746 21.1981
NCI-H322 CTRP2 -2.3918 2.7074 -3.4916 22.5553
HCC1833 CTRP2; CTRP1 -2.3817 0.4032 -2.6406 19.3692
NCI-H2030 GDSC1; GDSC2; CTRP2; CTRP1 -2.3401 1.5449 -2.4784 32.0229
NCI-H1435 GDSC1; GDSC2; CTRP2; CTRP1 -2.3234 2.2186 -2.4287 34.7602
NCI-H740 GDSC2 -2.2271 8.1988 -4.5194 52.7354
HCC44 GDSC1; GDSC2; CTRP2; CTRP1 -2.2036 1.6883 -2.2568 34.0967
NCI-H1838 GDSC1; GDSC2; CTRP2 -2.1556 0.4417 -2.4045 15.6887
HCC2108 CTRP2; CTRP1 -2.123 1.0483 -2.5598 18.2987
LXF 289 GDSC1; GDSC2; CTRP2; CTRP1 -2.0458 7.6481 -3.4867 36.0917
NCI-H1304 GDSC1 -2.0284 5.0483 -6.4841 16.9004
NCI-H3255 GDSC1; GDSC2; CTRP1 -2.0062 4.6483 -2.9023 36.5023
NCI-H2595 GDSC1; GDSC2 -1.9524 6.6831 -7.234 15.094
LCLC-103H GDSC1; GDSC2; CTRP2; CTRP1 -1.9439 3.4705 -2.2004 33.3598
NCI-H1975 GDSC1; GDSC2; CTRP1 -1.8797 3.9277 -2.2187 33.2476
HCC366 GDSC1; GDSC2; CTRP2 -1.8354 2.925 -2.2032 29.856
NCI-H1915 GDSC1; GDSC2; CTRP2; CTRP1 -1.7881 3.7864 -2.091 32.7529
NCI-H1792 GDSC1; GDSC2; CTRP2; CTRP1 -1.7646 2.1666 -1.8357 32.1268
LOU-NH91 GDSC1; GDSC2; CTRP2 -1.7446 7.506 -5.0792 23.4921
NCI-H1869 GDSC1; GDSC2; CTRP2 -1.6823 1.5036 -2.2535 13.9767
NCI-H2023 GDSC1; GDSC2; CTRP2; CTRP1 -1.6223 5.1503 -3.8274 19.2655
Lu-65 GDSC1; GDSC2; CTRP2; CTRP1 -1.612 2.8243 -1.7452 31.5696
NCI-H82 GDSC1; GDSC2; CTRP1 -1.5964 1.4461 -1.6165 31.2393
NCI-H2126 CTRP2; CTRP1 -1.4628 3.9263 -1.7663 34.4581
RERF-LC-KJ GDSC1; GDSC2; CTRP1 -1.43 2.9426 -1.5667 30.7447
NCI-H847 GDSC1; GDSC2 -1.4008 8.1307 -7.5367 15.2287
NCI-H2085 GDSC1; GDSC2; CTRP2 -1.4003 7.3095 -4.6619 21.4949
NCI-H841 GDSC1; GDSC2; CTRP1 -1.3423 8.5381 -5.3117 22.6524
Calu-6 GDSC1; GDSC2; CTRP2; CTRP1 -1.3132 3.3945 -1.5082 30.3444
NCI-H2803 GDSC1; GDSC2 -1.3084 6.2442 -2.7477 33.8025
NCI-H1299 GDSC1; GDSC2; CTRP2; CTRP1 -1.2616 2.883 -1.3799 29.9316
COR-L105 GDSC1; GDSC2; CTRP2 -1.2358 3.4124 -2.6294 14.2599
HCC95 CTRP2 -1.1737 1.1552 -1.5765 11.8551
RERF-LC-Sq1 GDSC1; GDSC2 -1.1403 4.1338 -5.4264 6.0884
NCI-H1755 GDSC1; GDSC2; CTRP2; CTRP1 -1.1208 5.4374 -3.488 17.0426
LC-1/sq-SF CTRP2; CTRP1 -1.0578 1.8868 -1.0825 31.7416
NCI-H1573 GDSC1; GDSC2; CTRP2; CTRP1 -1.035 2.6335 -1.1125 28.7991
T3M-10 CTRP2; CTRP1 -0.9746 3.7327 -2.5266 15.1341
HCC2935 CTRP2; CTRP1 -0.8929 6.6111 -3.8518 20.0643
MOR/CPR CTRP2 -0.8792 1.4947 -1.4033 10.3743
NCI-H1395 CTRP2 -0.8363 3.112 -2.0973 13.0602
HCC33 GDSC2; CTRP1 -0.7641 1.7439 -0.7762 50.3944
NCI-H64 GDSC1; GDSC2 -0.7552 5.1764 -5.67 6.5813
NCI-H1836 GDSC1; GDSC2; CTRP1 -0.7058 3.2237 -1.0472 26.8721
HCC4006 CTRP2; CTRP1 -0.6902 2.092 -1.4759 10.1757
NCI-H1373 CTRP2; CTRP1 -0.6404 4.2049 -0.9311 30.3082
NCI-H2869 GDSC1; GDSC2 -0.6185 6.3038 -2.0448 29.774
HCC1195 CTRP1 -0.4872 2.5765 -1.5972 19.1508
VMRC-LCD GDSC1; GDSC2; CTRP2; CTRP1 -0.4805 2.4659 -0.5185 26.1665
NCI-H835 GDSC1; GDSC2 -0.4699 3.0007 -4.5416 1.8088
ChaGo-K-1 GDSC1; GDSC2; CTRP2; CTRP1 -0.4326 2.6912 -0.4853 28.6532
SHP-77 GDSC1; GDSC2; CTRP2; CTRP1 -0.4229 1.5121 -0.4258 25.8215
HCC827 GDSC1; GDSC2; CTRP2; CTRP1 -0.3956 2.7986 -1.5247 8.5099
NCI-H2722 GDSC1; GDSC2 -0.1827 10.1756 -7.6675 13.6392
NCI-H345 GDSC1; GDSC2 -0.0925 7.7924 -2.1463 28.5696
NCI-H727 GDSC1; GDSC2; CTRP2; CTRP1 -0.0904 5.3115 -0.6026 25.512
UMC-11 GDSC1; GDSC2 -0.0492 2.2729 -4.0781 0.3517
NCI-H1993 GDSC1; GDSC2 0.0589 2.3074 -4.0499 0.278
NCI-H720 GDSC1; GDSC2 0.147 11.5012 -8.0797 14.5643
NCI-H2106 CTRP2 0.2213 5.1522 -2.1406 10.9177
Lu-165 GDSC1; GDSC2 0.2651 7.9081 -6.3037 7.78
NCI-H2066 GDSC1; GDSC2 0.367 2.423 -3.9796 0.1353
NCI-H1436 GDSC1; GDSC2 0.4467 5.2341 -0.4863 21.6386
RERF-LC-Ad2 CTRP2 0.485 3.5899 -1.1394 6.2012
NCI-H322M GDSC1; GDSC2 0.5104 10.6358 -7.4237 11.6997
LK2 CTRP2 0.6279 1.7925 -0.133 1.7204
NCI-H1770 GDSC1; GDSC2 0.7058 6.7774 -0.8814 22.3569
RERF-LC-Ad1 CTRP2 0.7899 3.4778 -0.843 4.4102
HCC1171 CTRP2 0.9925 5.3806 -1.6311 7.3563
NCI-H2291 GDSC1; GDSC2; CTRP2 1.0698 6.8051 -0.5274 17.6831
NCI-H1355 GDSC1; GDSC2; CTRP2; CTRP1 1.1089 8.02 -0.2555 22.2057
CAL-12T GDSC1; GDSC2; CTRP2; CTRP1 1.1935 5.4869 0.188 15.0569
BEN GDSC1; GDSC2; CTRP2; CTRP1 1.3634 6.5917 0.5675 21.6049
IA-LM GDSC1; GDSC2; CTRP2 1.3737 11.842 -4.5465 16.0275
HCC2279 CTRP2 1.7868 3.9604 -0.4197 1.4277
NCI-H2342 GDSC1; GDSC2; CTRP2; CTRP1 1.9141 7.112 -1.8104 5.8486
NCI-H196 GDSC1; GDSC2; CTRP2 2.2899 9.2535 -2.5846 8.0935
Calu-1 CTRP2 2.7639 13.0238 -4.0832 13.9245
EKVX GDSC1; GDSC2; CTRP2 3.3503 9.2267 0.3932 10.2614
NCI-H2135 GDSC1; GDSC2 3.7177 8.3784 1.1155 8.1851
NCI-H1563 GDSC1; GDSC2; CTRP2 3.9626 12.4456 -2.9938 7.4593
NCI-H2444 GDSC1; GDSC2 4.0283 12.8975 -0.8907 15.2807
NCI-H2172 GDSC1; GDSC2; CTRP2; CTRP1 5.7871 13.4179 0.1512 7.7062
Hs 888.Lu CTRP2 0.4126 7.9615 -3.3846 15.5218
⏷ Show the Full List of 224 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 -1.2611 7.9491 -7.3459 14.2557
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 -7.5251 -2.8779 -7.6235 52.6948
SYO-1 CTRP2 -7.4069 -4.5577 -7.4133 52.0546
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -4.3583 0.8674 -4.9323 33.4984
TYK-nu GDSC1; GDSC2; CTRP2; CTRP1 -9.6586 -1.4193 -10.142 57.3411
Caov-3 GDSC2; CTRP1 -8.9935 -2.8186 -9.0629 89.8847
TOV-112D GDSC1; GDSC2; CTRP2 -7.9027 -5.8676 -7.903 48.7495
OC 314 GDSC1; GDSC2; CTRP2 -7.1429 -5.83 -7.1429 44.2764
OVCAR-8 GDSC1; GDSC2; CTRP2; CTRP1 -6.936 -2.1106 -7.0877 43.3555
ES-2 GDSC1; GDSC2 -6.7927 -4.8143 -6.83 26.2634
A2780 GDSC1; GDSC2; CTRP2; CTRP1 -6.103 4.0605 -7.9556 41.4761
JHOS-2 GDSC1; GDSC2; CTRP2 -5.8848 -0.3383 -6.013 51.3645
OV56 GDSC1; GDSC2; CTRP2 -5.5932 -1.886 -5.6885 35.4238
OVK18 GDSC1; GDSC2; CTRP2; CTRP1 -5.4587 7.1635 -7.5284 49.3904
OV7 CTRP2; CTRP1 -5.1498 1.1627 -5.8858 38.8812
JHOC-5 CTRP2; CTRP1 -4.8615 -0.9398 -5.0416 35.61
OVCAR-3 GDSC1; GDSC2 -4.5833 4.9602 -8.556 25.7592
Caov-4 GDSC1; GDSC2 -4.5468 0.1103 -6.1416 16.2696
MCAS CTRP2 -4.4032 1.7552 -5.2715 34.6155
COV434 CTRP2; CTRP1 -4.2059 1.3609 -4.9236 32.9482
OVTOKO GDSC1; GDSC2; CTRP2 -4.1753 0.4957 -4.6236 28.16
HEY A8 CTRP1 -4.1294 0.1703 -4.1622 92.8436
OV-90 GDSC1; GDSC2; CTRP2; CTRP1 -3.6198 3.7063 -5.1929 28.3134
ES2 CTRP2 -3.4227 0.1324 -3.7053 26.3972
OVCAR-4 GDSC1; GDSC2; CTRP2; CTRP1 -3.3103 1.9903 -4.179 24.4438
OAW42 GDSC1; GDSC2; CTRP2; CTRP1 -3.2621 6.0407 -5.8585 29.1839
DOV13 GDSC1; GDSC2; CTRP2 -3.0472 2.4532 -4.0772 23.4421
JHOS-4 GDSC1; GDSC2; CTRP1 -2.5002 6.2569 -3.512 45.1887
RMUG-S CTRP1 -2.4489 5.1155 -4.7036 44.3627
OVKATE GDSC1; GDSC2; CTRP1 -2.4118 -0.3936 -2.5124 15.8746
IGROV-1 GDSC1; GDSC2; CTRP2; CTRP1 -2.1006 6.0582 -4.722 23.2092
EFO-27 GDSC1; GDSC2; CTRP2; CTRP1 -2.0768 2.7534 -2.4249 31.1368
ONCO-DG-1 CTRP2 -1.994 3.1933 -3.2909 20.7158
OVCAR-5 GDSC1; GDSC2; CTRP2 -1.9554 2.3006 -2.8651 16.7225
SK-OV-3 GDSC1; GDSC2; CTRP2; CTRP1 -1.9248 4.2556 -2.3381 33.6109
RMG-I GDSC1; GDSC2; CTRP2; CTRP1 -1.8892 2.6993 -2.9667 16.9147
TOV-21G GDSC1; GDSC2; CTRP2 -1.5738 6.1056 -4.2394 20.5228
SNU-119 CTRP2 -1.5369 1.0305 -1.9202 14.1964
EFO-21 GDSC1; GDSC2; CTRP2; CTRP1 -1.5298 6.8097 -2.6371 33.2856
OVISE GDSC1; GDSC2; CTRP2 -0.9815 -0.3275 -0.9876 8.0238
SNU-8 CTRP2 -0.9365 8.7401 -4.9431 23.8376
OVMANA CTRP1 -0.9132 1.3604 -0.9188 45.0666
OAW28 GDSC1; GDSC2; CTRP2 -0.2459 8.8016 -4.3641 18.2578
JHOM-1 CTRP2; CTRP1 0.0512 2.0065 -0.7221 5.3198
COV644 CTRP2; CTRP1 0.1629 2.1217 -0.6787 4.897
FU-OV-1 GDSC1; GDSC2; CTRP2 0.3721 10.2901 -4.5827 17.8269
COV318 CTRP1 0.4279 6.1093 -0.2796 37.3433
SNU-840 CTRP2; CTRP1 0.5998 3.9778 -1.2402 6.4129
OVSAHO CTRP2 0.6194 4.6188 -1.5444 7.6562
COV362 CTRP2; CTRP1 0.9789 9.4112 -3.6477 15.4188
Kuramochi GDSC1; GDSC2; CTRP2 4.0331 14.1074 -3.7313 9.7432
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 -2.0432 4.5044 -3.936 23.219
SW982 GDSC1; GDSC2 -9.5649 -4.3897 -9.8761 47.3264
Hs 633.T GDSC1; GDSC2 -8.9068 -5.5101 -8.988 42.2626
EW-8 GDSC1; GDSC2 -8.6915 -7.614 -8.6915 40.4126
GCT GDSC1; GDSC2; CTRP2 -7.9242 -4.2085 -7.949 48.8905
MFH-ino GDSC1; GDSC2 -7.7936 -4.2656 -7.9806 34.3289
SW872 GDSC1; GDSC2 -7.579 -6.2989 -7.5797 32.0422
VA-ES-BJ GDSC1; GDSC2 -7.1557 -4.9226 -7.2014 29.0268
KYM-1 GDSC1; GDSC2; CTRP2 -7.0622 -4.9272 -7.0631 43.8037
TE 441.T GDSC2; CTRP2 -7.0559 -1.1631 -7.1656 57.4175
A-204 GDSC1; GDSC2; CTRP2 -6.945 -0.7196 -7.343 43.782
G-402 GDSC1; GDSC2 -6.3778 -1.5199 -7.2774 26.5643
G-401 GDSC1; GDSC2; CTRP2; CTRP1 -5.5348 -1.2175 -5.5513 49.2499
MES-SA GDSC1; GDSC2 -5.4751 -2.2848 -6.0186 18.4355
Rh41 GDSC1; GDSC2; CTRP2 -5.2854 -1.1565 -5.4614 33.8452
TTC-709 CTRP2 -5.0107 1.9838 -6.0081 38.6072
Hs 729.T CTRP2 -4.9097 -0.0574 -5.2797 36.4712
RKN GDSC1; GDSC2; CTRP2; CTRP1 -4.7668 0.2838 -5.2111 31.5815
STS-0421 GDSC1; GDSC2 -4.6552 1.9118 -5.0432 50.857
Rh30 GDSC1; GDSC2 -4.5918 1.0447 -6.6366 18.5688
BT-16 CTRP2 -3.9404 -0.2924 -4.1701 29.6603
Rh18 GDSC1; CTRP2 -3.865 6.1458 -6.5125 35.7271
SK-LMS-1 GDSC1; GDSC2; CTRP2 -2.7891 5.9939 -5.3664 26.7047
SK-UT-1 GDSC1; GDSC2; CTRP2 -2.4016 4.6728 -4.3708 22.8059
HT-1080 GDSC1; GDSC2; CTRP2; CTRP1 -2.2596 4.9653 -4.3643 22.4546
RD GDSC1; GDSC2; CTRP2 -2.0045 8.0472 -5.5864 25.5
BT-12 CTRP2 -1.978 3.7515 -3.5253 21.552
Tm87-16 CTRP2 -1.3248 4.8024 -3.3749 19.3191
SW684 GDSC1; GDSC2 -0.7534 4.6911 -5.444 5.6302
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 0.6764 4.4979 -1.4385 7.1074
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; GDSC2; CTRP1 -6.6609 -2.9619 -6.6638 54.3913
NCI-H28 GDSC1; GDSC2; CTRP2; CTRP1 -3.8731 0.5539 -3.917 41.7127
NCI-H2452 GDSC1; GDSC2 -3.8227 1.7777 -6.3002 15.1467
MPP 89 GDSC1; GDSC2; CTRP2 -2.9523 4.398 -4.8032 25.4703
NCI-H2052 GDSC1; GDSC2; CTRP2; CTRP1 -2.2427 8.7578 -4.1078 37.5593
ACC-MESO-1 CTRP2 1.4204 3.2819 -0.3243 1.4532
IST-Mes1 GDSC1; GDSC2; CTRP2 2.6746 15.8066 -5.5156 16.904
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 GDSC1; GDSC2; CTRP2 -6.472 -2.1993 -6.5836 40.598
PC-3 GDSC1; GDSC2 -6.0218 -2.7654 -6.4372 21.9835
LNCaP clone FGC GDSC1; GDSC2; CTRP2 -5.0462 -1.118 -5.2105 32.4122
DU145 GDSC1; GDSC2; CTRP2 -4.8516 0.8859 -5.4755 32.5644
PaCa-3 CTRP2; CTRP1 -3.3136 4.1533 -3.8264 43.8124
VCaP GDSC1; GDSC2; CTRP2 -1.5184 3.6047 -2.9984 16.1814
NCI-H660 GDSC2 4.0813 9.7917 0.6961 14.1269
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 -6.9175 -6.0114 -6.9175 48.7947
A-253 GDSC1; GDSC2; CTRP2 3.9647 15.3757 -4.3828 11.8459
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -10.1688 -6.7542 -10.1694 84.0202
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NUGC-3 GDSC1; GDSC2; CTRP2 -7.6121 -0.8315 -8.0438 47.395
RF-48 GDSC1; GDSC2 -7.2242 -1.2028 -8.3014 33.1578
AGS GDSC1; GDSC2; CTRP2; CTRP1 -6.8822 0.1178 -7.4756 43.7044
SNU-1 GDSC1; GDSC2; CTRP2 -6.7903 -0.9538 -7.1256 42.8356
SNU-16 GDSC1; GDSC2; CTRP2 -6.7085 -2.732 -6.7792 41.8848
ECC10 GDSC1; GDSC2 -6.6543 -2.4275 -7.237 27.3565
23132/87 GDSC1; GDSC2; CTRP2 -6.5308 -2.5814 -6.6062 40.8585
SNU-601 CTRP2 -6.2822 -2.7847 -6.3299 44.6483
SNU-5 GDSC1; GDSC2; CTRP2 -6.267 -2.071 -6.3811 39.4113
OCUM-1 GDSC1; GDSC2 -6.1641 -1.2217 -7.172 25.443
RERF-GC-1B GDSC1; GDSC2 -6.1141 -1.9841 -6.8161 23.8482
ECC12 GDSC2; CTRP2 -5.7185 -4.3592 -5.7185 50.5164
NCI-N87 GDSC1; GDSC2; CTRP2 -5.2634 -2.0278 -5.3259 33.3943
TGBC11TKB GDSC1; GDSC2 -5.1373 -1.276 -6.082 17.6705
SK-GT-2 GDSC1; GDSC2 -4.3889 -1.4592 -5.2437 11.7529
GSS CTRP2 -4.3667 0.4381 -4.8165 33.1796
SNU-620 CTRP2 -4.3211 -1.4186 -4.3943 31.6745
HGC-27 GDSC1; GDSC2; CTRP2 -4.2287 4.0037 -5.9538 31.9829
GCIY GDSC1; GDSC2 -4.2272 1.0113 -6.2825 16.0659
TMK-1 GDSC1; GDSC2 -3.9484 2.0812 -4.3113 46.8618
IM95 GDSC1; GDSC2 -3.875 0.8465 -5.8833 13.3819
MKN28 GDSC1; GDSC2 -3.6801 1.4 -5.9876 13.3965
NUGC-4 GDSC1; GDSC2; CTRP2; CTRP1 -3.2291 0.6426 -3.2582 38.7392
Fu97 GDSC1; GDSC2; CTRP2; CTRP1 -2.5242 2.4159 -2.6639 35.7512
Hs 746.T GDSC1; GDSC2; CTRP2 -1.7559 8.6838 -5.664 25.1676
SNU-719 CTRP2 -1.6439 2.9657 -2.8332 18.0291
SNU-216 CTRP2 -1.6043 2.6338 -2.6453 17.1903
MKN74 CTRP2; CTRP1 -1.2684 1.5498 -1.2847 32.7851
LMSU CTRP2 -1.1091 7.6338 -4.5529 22.9948
MKN7 GDSC1; GDSC2; CTRP2; CTRP1 -0.9497 5.3696 -1.5566 32.6206
SH-10-TC CTRP2; CTRP1 -0.7735 1.5816 -0.7815 30.2626
HuG1-N CTRP2 -0.6487 1.8608 -1.3286 9.4767
MKN45 GDSC1; GDSC2; CTRP2 -0.1111 6.0872 -2.8935 12.9665
GSU CTRP2 0.5409 1.8677 -0.2354 2.2924
MKN1 GDSC1; GDSC2; CTRP2 0.7181 7.4327 -2.8698 11.4359
HSC-39 GDSC1; GDSC2 0.7776 15.8674 -9.7521 18.7136
KE-39 CTRP2 0.7975 8.1079 -3.1428 13.8481
KATO III GDSC1; GDSC2; CTRP2 0.9579 12.4428 -5.1779 18.6203
SCH GDSC1; GDSC2 2.3111 8.9046 -0.3509 16.6519
SNU-668 CTRP2 2.5036 8.7425 -2.1925 7.3099
SNU-685 CTRP2 -4.2074 1.4816 -4.9656 33.0771
SNG-M GDSC1; GDSC2; CTRP2; CTRP1 -2.4723 3.7769 -2.8306 35.9646
SNU-1077 CTRP2 0.5009 2.7447 -0.7042 4.3367
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1; GDSC2 -9.5022 -7.0742 -9.5104 46.5313
FTC-133 GDSC1; GDSC2; CTRP2 -7.4402 -4.9063 -7.4428 46.0319
K5 GDSC1; GDSC2 -7.3467 -4.093 -7.5303 30.9818
CAL-62 GDSC1; GDSC2; CTRP2 -7.1488 -1.8783 -7.3483 44.6395
SW579 CTRP2 -6.7496 -3.7763 -6.7635 47.6906
ML-1 [Human leukemia] GDSC1; GDSC2 -6.6957 -0.4071 -6.8635 62.1818
CGTH-W-1 GDSC1; GDSC2; CTRP2 -6.6793 -3.7334 -6.6931 41.5831
8505C GDSC1; GDSC2; CTRP2 -6.5038 -1.9445 -6.6491 40.8562
ASH-3 GDSC1; GDSC2 -5.9398 -2.1241 -6.5766 22.2893
WRO GDSC1; GDSC2 -5.5343 0.7121 -7.3865 24.3056
B-CPAP GDSC1; GDSC2; CTRP2 -5.0771 0.0423 -5.487 33.2782
KMH-2 GDSC1; GDSC2 -4.6088 -0.7829 -4.645 50.68
TT2609-C02 GDSC1; GDSC2; CTRP2 -4.6003 1.2782 -5.3249 31.4094
HTC-C3 GDSC1; GDSC2 -4.3283 -1.2747 -5.2702 11.7065
8305C GDSC1; GDSC2; CTRP2 -3.5052 2.0069 -4.3943 25.6304
TT GDSC1; GDSC2; CTRP2 -3.3563 4.3156 -5.1807 27.5923
BHT-101 GDSC1; GDSC2; CTRP2 -2.9836 3.6358 -4.5016 24.6253
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SAS GDSC1; GDSC2 -9.4223 -6.8685 -9.4344 45.94
HO-1-N-1 GDSC1; GDSC2 -9.3955 -7.1171 -9.4014 45.7256
FaDu GDSC1; GDSC2; CTRP2 -9.2072 -6.4219 -9.2086 56.4108
HSC-4 GDSC1; GDSC2 -8.7546 -7.1059 -8.7557 40.8912
PCI-04B GDSC1; GDSC2 -8.4586 -6.1207 -8.4587 75.127
CAL-27 GDSC1; GDSC2 -8 -5.0924 -8.075 35.4791
Ca9-22 GDSC1; GDSC2 -7.9661 -4.7949 -8.0773 35.3519
KON GDSC1; GDSC2 -7.9177 -2.8555 -7.9525 69.9281
JHU-011 GDSC1; GDSC2 -7.79 -5.2069 -7.7902 70.8737
BICR 78 GDSC1; GDSC2 -7.6641 -4.4703 -7.8038 33.1949
JHU-029 GDSC1; GDSC2 -7.3657 -1.69 -7.4469 66.318
BB30-HNC GDSC1; GDSC2 -7.3019 -4.4925 -7.3025 67.7529
JHU-022 GDSC1; GDSC2 -7.1985 -4.221 -7.3453 29.7333
CAL-33 GDSC1; GDSC2; CTRP2 -7.1865 -4.146 -7.1982 44.5587
HSC-2 GDSC1; GDSC2; CTRP2; CTRP1 -7.0201 -2.6103 -7.0291 55.9953
HO-1-u-1 GDSC1; GDSC2 -6.9626 -0.83 -8.1725 31.7904
BICR 22 GDSC1; GDSC2; CTRP2 -6.936 -1.6595 -7.1542 43.4656
OSC-20 GDSC1; GDSC2 -6.8455 -3.854 -7.0362 27.254
SKN-3 GDSC1; GDSC2 -6.6829 -2.8752 -7.1209 27.0051
KOSC-2 GDSC1; GDSC2 -6.6085 0.2681 -6.8603 61.3103
BICR 10 GDSC1; GDSC2 -6.2781 -1.2727 -7.2711 26.2063
SCC-15 GDSC1; GDSC2 -6.2476 -0.9626 -7.367 26.4748
HSC-3 GDSC1; GDSC2; CTRP2 -6.2379 -2.5644 -6.3006 39.1154
NCI-H3118 GDSC1; GDSC2 -6.1546 -0.6868 -7.3868 26.2457
PCI-06A GDSC1; GDSC2 -6.0091 2.0167 -6.5369 57.5773
DOK GDSC1; GDSC2 -5.6813 -0.2173 -7.1074 23.6533
BICR 56 CTRP2 -5.5582 -1.4721 -5.705 40.1072
PCI-15A GDSC1; GDSC2 -5.5485 -2.8535 -5.5503 56.6769
PCI-30 GDSC1; GDSC2 -5.3421 -0.3759 -6.6934 20.9223
PE/CA-PJ34 (clone C12) CTRP2 -5.2933 -1.3807 -5.4349 38.3502
PCI-38 GDSC1 -5.1799 -0.5008 -6.4736 28.0935
Detroit 562 GDSC1; GDSC2; CTRP2 -5.0765 -0.2125 -5.4243 33.1049
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 -4.9293 0.6869 -5.1243 46.3376
SNU-1076 CTRP2 -4.9231 0.9469 -5.5719 37.2814
SCC-4 GDSC1; GDSC2; CTRP2 -4.9106 -1.5933 -4.9989 31.3952
BHY GDSC1; GDSC2; CTRP2 -4.6912 1.4197 -4.9868 45.1855
BICR 6 CTRP2 -4.631 0.3098 -5.0699 34.8622
SCC-25 GDSC1; GDSC2; CTRP2 -3.994 1.9355 -4.3309 41.5549
OSC-19 GDSC1; GDSC2 -3.9229 -0.3692 -3.9591 46.37
UPCI-SCC-090 GDSC1; GDSC2 -3.3899 1.2699 -5.6747 11.2898
PE/CA-PJ41 (clone D2) CTRP2 -3.1694 1.5859 -3.8793 26.221
BB49-HNC GDSC1 -3.1471 2.7071 -6.192 18.6334
SAT [Human HNSCC] GDSC1; GDSC2 -2.9608 4.6927 -7.0324 16.3315
YD-10B CTRP2 -2.7509 1.5716 -3.4234 23.3365
SNU-1066 CTRP2 -2.7309 1.2721 -3.295 22.8085
SCC-9 GDSC1; GDSC2; CTRP2; CTRP1 -2.2615 4.8039 -4.2914 22.2262
SNU-899 CTRP2 -1.96 1.6844 -2.6196 18.0577
SNU-1214 CTRP2 -1.5203 0.4814 -1.7227 13.4133
LB771-HNC GDSC1; GDSC2 -0.6618 9.0932 -7.4766 13.7202
SNU-46 CTRP2 -0.1983 4.0493 -1.9572 11.0259
BICR 16 CTRP2 -0.0605 33.1792 -16.3891 38.7913
BICR 18 CTRP2 -0.0359 4.3016 -1.9383 10.6014
BICR 31 GDSC2; CTRP2 0.7261 5.2493 -0.1983 17.3685
SNU-1041 CTRP2 1.2479 6.0516 -1.7701 7.5042
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
647V GDSC1; GDSC2; CTRP2 -9.6019 -7.6682 -9.6019 58.7499
639V GDSC1; GDSC2; CTRP2 -9.4838 -8.0396 -9.4838 58.0566
BFTC-905 GDSC1; GDSC2 -9.192 -6.9898 -9.1977 44.1961
UM-UC-3 GDSC1; GDSC2; CTRP1 -7.6529 -6.0113 -7.6529 58.9522
CAL-29 GDSC1; GDSC2; CTRP2 -7.1377 -3.3756 -7.1796 44.3301
5637 GDSC1; GDSC2; CTRP2; CTRP1 -6.8325 -3.3731 -6.834 55.1809
J82 GDSC1; GDSC2; CTRP2 -6.6067 -2.6749 -6.6775 41.2911
T24 GDSC1; GDSC2; CTRP2 -6.1155 -0.1341 -6.2804 52.537
JMSU-1 CTRP2 -5.3692 -1.9883 -5.441 38.6567
SW780 GDSC1; GDSC2 -4.9829 -2.0513 -5.5898 15.0406
KMBC-2 CTRP2; CTRP1 -4.7511 -0.0152 -4.7931 50.341
RT-4 GDSC1; GDSC2; CTRP2; CTRP1 -4.6154 1.0585 -4.7279 45.1778
RT-112 GDSC1; GDSC2; CTRP2 -4.4208 -1.1442 -4.5357 28.5943
U-BLC1 CTRP2 -3.3736 2.3339 -4.3775 28.5413
KU-19-19 GDSC1; GDSC2; CTRP2 -3.363 3.1285 -4.6838 26.1484
VM-CUB-1 CTRP2 -1.8888 2.187 -2.7479 18.3526
TCCSUP GDSC1; GDSC2; CTRP2 -1.7154 3.8353 -3.3008 17.6721
253J-BV CTRP2 -1.4324 3.169 -2.712 17.0074
253J CTRP2 -0.7204 5.2209 -3.0101 16.4729
UM-UC-1 CTRP2 0.3197 6.9499 -2.9563 14.0415
SW1710 GDSC1; GDSC2; CTRP2 1.4551 4.2374 -0.7444 2.6523
BC-3C CTRP2 1.7717 11.8689 -4.2509 16.1313
HT-1197 GDSC1; CTRP2 2.1104 7.5799 -1.9011 6.7153
HT-1376 GDSC1; GDSC2; CTRP2; CTRP1 3.9169 9.5847 1.8694 11.5199
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NT2-D1 GDSC1; GDSC2 -10.7121 -6.1801 -10.8236 55.1796
TC-YIK GDSC1; GDSC2 -9.3514 -7.1185 -9.3568 45.3934
PA-1 GDSC1; GDSC2 -9.1779 -4.8203 -9.3748 44.4846
SiSo GDSC1; GDSC2 -8.2495 -6.0377 -8.2644 37.1404
C-33 A GDSC1; GDSC2 -8.2454 -3.8944 -8.5503 38.0299
PWR-1E GDSC1; GDSC2 -8.2381 -5.3502 -8.2991 37.2155
ME-180 GDSC1; GDSC2 -8.1396 -5.675 -8.1698 36.3689
MS751 GDSC1; GDSC2 -7.842 -4.1091 -8.0644 34.8099
NEC8 GDSC1; GDSC2 -7.8391 -5.9661 -7.8476 34.0288
BPH-1 GDSC1; GDSC2 -7.8129 -5.2954 -7.8575 33.9653
HEY GDSC1; GDSC2 -7.7361 -5.5959 -7.7569 33.2998
Ca Ski GDSC1; GDSC2 -7.7292 -5.0394 -7.7943 33.4114
SW756 GDSC1; GDSC2 -7.6242 -3.7139 -7.9162 33.4378
HT-3 GDSC1; GDSC2 -7.4383 -5.6838 -7.4474 31.0149
KGN GDSC1; GDSC2 -7.4139 -2.8706 -7.9185 32.6301
DoTc2 4510 GDSC1; GDSC2 -7.3786 -3.2781 -7.7611 31.9445
PEO1 GDSC1; GDSC2 -7.1686 -4.2031 -7.3164 29.513
SW954 GDSC1; GDSC2 -7.0064 -0.6171 -7.1685 63.7763
SKN GDSC1; GDSC2 -6.3964 -1.89 -7.1537 26.1446
CAL-39 GDSC1; GDSC2 -6.2874 -2.8534 -6.6973 23.9462
DSH1 GDSC1; GDSC2 -6.1775 -3.8622 -6.3092 22.0022
SKG-IIIa GDSC1; GDSC2 -5.9442 -0.9948 -7.0371 24.194
UWB1.289 GDSC1; GDSC2 -5.8424 1.0177 -6.1576 57.2541
LB831-BLC GDSC1; GDSC2 -5.7608 -0.388 -7.1119 23.9168
C-4-I GDSC1; GDSC2 -5.6837 -2.8243 -6.0507 19.2511
OVCA433 GDSC1; GDSC2 -5.4707 2.3954 -6.0375 54.9392
HEC-1 GDSC1; GDSC2 -5.2893 0.2 -6.9059 21.656
ACC-OV7 GDSC1; GDSC2 -5.1634 -0.2715 -5.2597 53.9917
JAR GDSC1; GDSC2 -3.7588 0.3766 -3.8443 45.4119
SiHa GDSC1; GDSC2 -3.5292 5.0824 -7.698 20.2062
OVMIU GDSC1; GDSC2 -3.4142 0.1966 -5.1587 8.9212
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 -3.3338 3.4992 -3.9908 43.6809
JHOS-3 GDSC1; GDSC2 -2.6729 3.7201 -3.3333 39.8881
JEG-3 GDSC1; GDSC2 -2.1286 11.712 -5.976 41.7046
OVCA420 GDSC1; GDSC2 -1.8735 4.7105 -6.2043 10.6695
SW962 GDSC1; GDSC2 -1.3197 8.9857 -3.9267 36.4042
OV17R GDSC1; GDSC2 -1.3081 7.5233 -3.2769 35.0449
NCC-IT GDSC2 0.1486 2.2263 -7.2996 0.0072
HeLa GDSC1; GDSC2; CTRP2 11.0368 31.4197 -7.4163 12.3307
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

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