Details of the Drug

General Information of Drug (ID: DMW78BX)

Drug Name
HBX-41108
Synonyms
USP inhibitors (cancer), Hybrigenics; USP-7 inhibitors, Hybrigenics; USP-7 inhibitors (cancer), Hybrigenics; USP-9 inhibitors (cancer), Hybrigenics; Ubiquitin-specific protease inhibitors (cancer), Hybrigenics; Ubiquitin-specific protease-7 inhibitors (cancer), Hybrigenics
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Preclinical [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C13H3ClN4O
Canonical SMILES
C1=CC2=C(C=C1Cl)C(=O)C3=NC(=C(N=C23)C#N)C#N
InChI
1S/C13H3ClN4O/c14-6-1-2-7-8(3-6)13(19)12-11(7)17-9(4-15)10(5-16)18-12/h1-3H
InChIKey
BIGPXXAUSQLTQR-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
16065773
CAS Number
924296-39-9
TTD ID
D0I9UP

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 105 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 2.6028 3.0621 2.6028 22.9282
JM1 CTRP2 2.4877 3.4422 2.4875 23.696
SK-MM-2 CTRP2 -2.7682 10.2179 -4.9653 54.8768
KMS-28BM CTRP2 -0.5094 1.5039 -0.5108 43.6665
KMS-34 CTRP2 0.4647 1.0382 0.4647 37.1725
KMS-18 CTRP2 0.4924 1.597 0.4924 36.9883
NB4 CTRP2 0.7187 1.7809 0.7186 38.1103
SUP-M2 CTRP2 1.2417 2.9169 1.2389 32.0059
SUP-T11 CTRP2 1.2782 3.0268 1.2742 31.7664
KMS-11 CTRP2 1.3346 2.6748 1.3341 31.3792
Ri-1 CTRP2 1.4162 3.5272 1.4008 30.8853
Pfeiffer CTRP2 1.4318 3.821 1.4009 30.833
OPM-2 CTRP2 1.5429 2.7754 1.5425 29.9911
TALL-1 [Human adult T-ALL] CTRP2 1.6098 3.3895 1.603 29.5667
RS4;11 CTRP2 1.6216 3.0601 1.6201 29.4701
SKM-1 CTRP2 1.6402 2.4678 1.6402 31.5156
SU-DHL-6 CTRP2 2.0372 6.593 1.51 28.4956
EoL-1 CTRP2 2.0613 3.3517 2.0599 26.5407
Mono-Mac-1 CTRP2 2.1539 4.758 2.0681 26.2093
KMS-12-BM CTRP2 2.1683 3.6301 2.1644 25.8361
RCH-ACV CTRP2 2.1716 3.6991 2.1663 25.8189
ME1 CTRP2 2.2039 5.0715 2.0731 27.958
MOLT-3 CTRP2 2.2219 2.9685 2.2218 25.4663
697 CTRP2 2.2456 3.3375 2.2451 25.3096
A3/Kawakami CTRP2 2.28 2.8526 2.28 25.0792
Hs 611.T CTRP2 2.3232 4.8122 2.2414 25.0681
HuT 78 CTRP2 2.3642 4.6255 2.3081 24.7074
AML-193 CTRP2 2.3729 3.126 2.3729 24.4598
EB1 CTRP2 2.3735 3.5871 2.3721 24.4605
GA-10 CTRP2 2.382 3.1571 2.382 24.3992
EJM CTRP2 2.3845 5.0522 2.2709 24.7694
SEM CTRP2 2.3915 3.0651 2.3915 24.3359
Mino CTRP2 2.398 2.9514 2.398 24.2927
OCI-AML-3 CTRP2 2.4278 2.9934 2.4278 24.0943
Daudi CTRP2 2.4415 3.0608 2.4415 24.003
Kasumi-2 CTRP2 2.4455 3.511 2.445 23.978
KO52 CTRP2 2.5008 2.9351 2.5008 23.6079
KMS-20 CTRP2 2.5169 3.24 2.5169 23.501
HD-MY-Z CTRP2 2.5388 3.3302 2.5388 23.3547
Namalwa CTRP2 2.5461 3.4587 2.5459 23.3068
U-937 CTRP2 2.569 4.6899 2.5177 23.3268
DB CTRP2 2.5749 3.454 2.5748 23.1148
DND-41 CTRP2 2.5802 3.3015 2.5801 23.0793
OCI-AML-2 CTRP2 2.5892 4.3403 2.5686 24.7989
RL CTRP2 2.604 3.1574 2.604 22.9201
OCI-M1 CTRP2 2.613 3.0963 2.613 22.8605
ST486 CTRP2 2.6246 3.3654 2.6246 22.7831
Granta-519 CTRP2 2.6259 4.9265 2.5488 23.0357
Kasumi-1 CTRP2 2.6441 3.527 2.6439 22.6539
NU-DHL-1 CTRP2 2.6618 5.3987 2.507 23.0666
A4/Fukuda CTRP2 2.6632 3.266 2.6632 22.5258
JeKo-1 CTRP2 2.6967 3.1859 2.6967 22.3029
M-07e CTRP2 2.6979 3.7114 2.6972 22.2973
F-36P CTRP2 2.6984 3.6885 2.6978 22.2936
SUP-T1 CTRP2 2.7028 4.2466 2.6908 23.9553
MOTN-1 CTRP2 2.703 3.5195 2.7029 22.2614
CA46 CTRP2 2.7094 4.2436 2.6977 22.2571
PL21 CTRP2 2.7099 4.8629 2.6468 24.0903
HL-60 CTRP2 2.7102 3.4562 2.7101 22.2131
HEL 92.1.7 CTRP2 2.7106 3.1692 2.7106 22.2103
Ci-1 CTRP2 2.7334 3.1476 2.7334 22.0585
K-562 CTRP2 2.7346 3.4181 2.7346 22.0505
L-540 CTRP2 2.803 5.5798 2.6221 22.218
SET-2 CTRP2 2.8059 3.9824 2.8034 21.5837
MM1.S CTRP2 2.8534 6.039 2.5634 22.2701
THP-1 CTRP2 2.8965 5.3573 2.7693 21.4072
HPB-ALL CTRP2 3.0087 4.5621 2.9897 20.2881
LP-1 CTRP2 3.0655 4.7902 3.0309 19.9623
Reh CTRP2 3.074 4.9427 3.0238 21.438
TF-1 CTRP2 3.1532 4.3522 3.1477 19.2799
RPMI-8226 CTRP2 3.2539 5.5591 3.1165 20.4757
SUP-B15 CTRP2 3.3305 4.5609 3.3217 18.1097
Mono-Mac-6 CTRP2 3.586 9.6994 1.9098 22.5879
Karpas-299 CTRP2 3.6561 6.0665 3.4319 16.6962
SU-DHL-4 CTRP2 3.666 5.5465 3.5658 16.1885
SIG-M5 CTRP2 3.7389 4.864 3.7276 15.3973
U266B1 CTRP2 3.7469 5.518 3.6587 15.6082
OCI-Ly3 CTRP2 3.8048 5.7762 3.6679 15.3939
NOMO-1 CTRP2 3.8075 5.3666 3.7493 16.2194
L-363 CTRP2 3.8825 5.6235 3.7852 15.8288
SUP-HD1 CTRP2 3.897 5.5645 3.8123 14.5962
SR CTRP2 3.924 5.5906 3.8366 15.4948
KYO-1 CTRP2 4.0151 7.113 3.4679 15.5169
Toledo CTRP2 4.0352 8.0271 3.1124 16.8361
BV-173 CTRP2 4.0618 6.2893 3.8092 14.1023
MOLT-13 CTRP2 4.1208 6.7073 3.7329 15.2666
Karpas-422 CTRP2 4.2276 5.721 4.1397 12.4058
BL-70 CTRP2 4.2728 5.1297 4.2645 11.8304
MC116 CTRP2 4.4795 5.1525 4.4759 10.4376
AMO1 CTRP2 4.4999 5.3203 4.4882 10.3291
SU-DHL-8 CTRP2 4.5175 6.28 4.3083 10.9147
OCI-Ly19 CTRP2 4.533 6.3472 4.3033 10.8875
CMK CTRP2 4.6388 5.8024 4.5691 9.604
P3HR-1 CTRP2 4.6464 5.2242 4.6439 9.3219
GDM-1 CTRP2 4.6832 6.5751 4.3864 10.8937
REC-1 CTRP2 4.7826 9.9044 2.9831 15.4871
RPMI-6666 CTRP2 4.7904 5.4653 4.7802 8.3888
MOLP-2 CTRP2 4.8526 6.2207 4.6916 8.5108
MHH-CALL-3 CTRP2 4.9756 7.0128 4.5217 9.469
JJN-3 CTRP2 5.0605 5.9099 5.0042 6.7493
Raji CTRP2 5.1485 5.882 5.1058 6.5687
L-428 CTRP2 5.2797 6.6087 5.0088 6.0973
OCI-AML-5 CTRP2 5.4797 5.9171 5.4576 3.8376
Karpas-620 CTRP2 5.583 7.684 4.8142 6.1361
OCI-Ly10 CTRP2 7.7339 12.7403 3.9782 5.9041
⏷ Show the Full List of 105 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 2.2389 3.5702 2.2367 25.36
TE15 CTRP2 4.6328 6.4164 4.3884 10.2794
TE-5 CTRP2 2.7277 4.2274 2.7172 22.1314
OE33 CTRP2 2.913 4.3718 2.9012 20.9013
OE19 CTRP2 2.9678 4.3046 2.9601 20.5227
KYSE-70 CTRP2 3.8516 8.2141 2.842 18.3743
KYSE-30 CTRP2 4.1244 5.5683 4.0572 13.0209
OE21 CTRP2 4.2455 6.1138 4.0618 12.6295
TE-1 CTRP2 4.2969 6.4478 4.0137 12.6533
KYSE-520 CTRP2 4.4947 6.198 4.3088 10.9807
TE-4 CTRP2 4.6781 5.5733 4.6505 9.1959
TE-11 CTRP2 4.6943 6.7051 4.3496 10.2504
TE-6 CTRP2 4.7379 5.5956 4.7113 8.7943
KYSE-150 CTRP2 5.0297 5.7765 4.997 6.8713
EC-GI-10 CTRP2 5.0385 6.1841 4.9055 7.1724
KYSE-410 CTRP2 5.2667 6.1807 5.155 5.9915
TE-14 CTRP2 5.4125 16.2545 0.4037 23.2212
KYSE-510 CTRP2 5.4546 6.7047 5.1496 5.0801
KYSE-450 CTRP2 5.5394 6.3071 5.4045 3.8569
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 3.6753 5.1353 3.6388 15.9064
HuP-T4 CTRP2 1.2661 3.318 1.255 31.8708
Capan-2 CTRP2 1.8054 3.9732 1.7789 28.3297
MIA PaCa-2 CTRP2 2.3757 4.5032 2.3329 24.5857
Panc 08.13 CTRP2 2.5321 4.3146 2.511 23.4701
SW1990 CTRP2 2.659 6.4425 2.2339 24.0437
HuP-T3 CTRP2 3.0367 5.1099 2.9619 20.292
PSN1 CTRP2 3.2501 4.8075 3.2231 18.7067
PaTu 8988s CTRP2 3.5429 5.7051 3.399 17.162
Capan-1 CTRP2 3.5793 5.9595 3.3769 17.1282
SU.86.86 CTRP2 3.7962 5.2806 3.7494 15.1364
L3.3 CTRP2 3.8374 5.6952 3.7214 15.103
AsPC-1 CTRP2 3.8914 6.3193 3.6143 15.3242
YAPC CTRP2 4.3028 21.3242 -3.0914 33.3421
SNU-410 CTRP2 4.3504 7.9592 3.4663 14.6188
PK-45H CTRP2 4.3974 13.5117 0.8628 24.1014
Panc 10.05 CTRP2 4.4812 7.3928 3.8462 12.7803
Panc 02.03 CTRP2 4.589 6.8763 4.171 11.2272
Panc 04.03 CTRP2 4.6041 6.1961 4.4286 10.2154
PaTu 8988t CTRP2 4.7764 5.3149 4.7736 8.4571
KP-2 CTRP2 5.1596 6.1586 5.0454 6.299
DAN-G CTRP2 5.2351 6.4044 5.0421 6.0928
Hs 766T CTRP2 5.7077 7.5233 5.0085 5.0507
PaTu 8902 CTRP2 5.9172 7.34 5.2878 3.4348
PK-59 CTRP2 6.2373 9.6202 4.4146 6.4868
Panc 05.04 CTRP2 7.5573 17.137 1.7029 14.8798
HPAC CTRP2 8.0101 9.7951 5.4459 0.4612
TCC-Pan2 CTRP2 8.5149 14.638 3.5907 6.3715
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 2.4855 11.4726 -0.0037 31.635
SK-MEL-5 CTRP2 1.4213 4.251 1.3521 31.0304
MDA-MB-435S CTRP2 1.6719 3.9309 1.6431 29.2267
WT2-iPS CTRP2 1.7191 3.8032 1.6994 28.8816
Hs 852.T CTRP2 1.7223 5.0218 1.5623 29.3336
WM115 CTRP2 1.8053 4.5026 1.7299 28.4951
G-361 CTRP2 1.9097 4.255 1.8662 27.6923
WM266-4 CTRP2 2.1685 4.213 2.14 25.9176
COLO 792 CTRP2 2.3138 4.9736 2.2076 25.2146
Malme-3M CTRP2 2.4279 5.5032 2.2311 24.7692
RVH-421 CTRP2 2.5071 3.0782 2.5071 23.5662
HMCB CTRP2 2.6975 3.0962 2.6975 22.2972
WM88 CTRP2 2.8013 5.7679 2.5766 22.3841
UACC-257 CTRP2 2.8334 5.2464 2.7213 21.775
SK-MEL-3 CTRP2 2.84 4.6802 2.8043 21.4683
MeWo CTRP2 2.8494 4.4983 2.8284 21.3561
COLO 800 CTRP2 2.9015 5.2129 2.8005 21.2827
HT-144 CTRP2 2.9713 4.8628 2.9241 20.6329
Hs 940.T CTRP2 3.1188 5.2393 3.0299 19.7936
Hs 944.T CTRP2 3.1922 5.0776 3.1325 19.204
Hs 294T CTRP2 3.2226 5.2089 3.1462 19.0593
A-375 CTRP2 3.2408 6.9308 2.7038 20.6013
LOX-IMVI CTRP2 3.2964 5.4832 3.178 18.7136
COLO 829 CTRP2 3.4455 6.2611 3.1461 18.3692
SK-MEL-24 CTRP2 3.5318 5.8414 3.355 17.3531
IGR-1 CTRP2 3.6885 6.4691 3.3459 16.9133
WM793 CTRP2 3.7441 8.3277 2.6818 19.2778
A101D CTRP2 3.7573 6.4311 3.4331 16.3884
SK-MEL-2 CTRP2 3.7624 4.8522 3.7526 15.2358
IPC-298 CTRP2 3.7877 5.7388 3.6578 15.483
Hs 839.T CTRP2 4.0807 5.3844 4.0389 13.2242
UACC-62 CTRP2 4.1062 5.8839 3.9707 13.3827
Hs 688(A).T CTRP2 4.2907 8.2673 3.2686 15.5545
SK-MEL-31 CTRP2 4.3626 5.5977 4.3089 11.3876
SK-MEL-28 CTRP2 4.3796 6.8158 3.971 12.5769
CJM [Human melanoma] CTRP2 4.4353 5.0112 4.4342 10.7236
K029AX CTRP2 4.452 11.2911 1.9991 20.0726
WM1799 CTRP2 4.473 8.5569 3.3208 14.8837
IGR-37 CTRP2 4.4744 7.0678 3.9734 12.3041
A2058 CTRP2 4.5926 6.193 4.417 10.2921
Hs 895.T CTRP2 4.7397 6.2944 4.5452 9.3844
SK-MEL-30 CTRP2 4.8283 5.8482 4.7652 8.3194
WM983B CTRP2 4.9326 7.9059 4.0788 10.6921
Mel JuSo CTRP2 5.6579 6.7539 5.3321 4.1184
Hs 934.T CTRP2 5.9668 8.3355 4.8335 5.2415
Hs 936.T CTRP2 6.788 12.206 3.5592 9.0683
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 3.5032 6.5044 3.1331 18.2451
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-212 CTRP2 -0.8516 3.0737 -0.9253 46.0643
NB1 CTRP2 1.6022 2.1675 1.6022 31.7876
SK-N-BE(2) CTRP2 2.3327 3.5249 2.3316 24.7315
SK-N-SH CTRP2 2.6123 3.5354 2.6121 22.8658
IMR-32 CTRP2 2.6519 3.0475 2.6519 22.6014
SK-N-FI CTRP2 2.7232 3.712 2.7227 22.128
Kelly CTRP2 2.8371 4.2249 2.8293 22.9791
SK-N-DZ CTRP2 2.9895 4.3279 2.9814 20.3792
KP-N-YN CTRP2 3.4665 8.1253 2.4793 20.8019
SK-N-AS CTRP2 3.4986 4.9871 3.4677 17.0648
NH-6 CTRP2 3.6825 5.1947 3.6394 15.8813
KP-N-SI9s CTRP2 4.6241 9.8816 2.8435 17.6033
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-869 CTRP2 3.598 6.2612 3.3124 17.3052
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-673 CTRP2 2.0857 3.2486 2.0851 26.3752
SK-N-MC CTRP2 2.8364 3.2881 2.8364 21.3721
SK-ES-1 CTRP2 3.0002 4.3908 2.99 20.3148
MG-63 CTRP2 3.4198 4.4727 3.4158 17.4989
Hs 888.T CTRP2 4.3492 11.4644 1.8183 20.9807
CAL-78 CTRP2 4.4329 6.8178 4.0273 12.2124
TC71 CTRP2 4.4854 5.2376 4.4783 10.4098
SJSA-1 CTRP2 4.5922 5.6664 4.5445 9.8374
G-292 clone A141B1 CTRP2 4.8185 7.6049 4.101 10.8905
SaOS-2 CTRP2 5.2649 7.036 4.809 6.9234
Hs 822.T CTRP2 6.0483 7.0954 5.5222 2.1875
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 58 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1428 CTRP2 1.2547 2.7054 1.2538 31.9126
MDA-MB-157 CTRP2 1.3902 3.158 1.3853 31.0231
MDA-MB-415 CTRP2 1.5906 3.438 1.5822 29.7
ZR-75-1 CTRP2 1.5941 2.2023 1.5941 29.6488
EFM-192A CTRP2 1.8148 3.7839 1.799 28.2311
AU565 CTRP2 2.0494 3.5566 2.0453 26.6289
HCC2218 CTRP2 2.1065 3.8544 2.0954 26.2719
HCC1500 CTRP2 2.222 3.6684 2.2181 25.4783
SK-BR-3 CTRP2 2.2955 4.1106 2.278 25.0342
DU4475 CTRP2 2.299 3.8732 2.2913 24.9779
BT-549 CTRP2 2.3227 3.5454 2.3214 24.7988
BT-20 CTRP2 2.3637 3.7909 2.3593 24.536
MDA-MB-361 CTRP2 2.3645 3.4381 2.3639 24.518
Hs 578Bst CTRP2 2.4896 3.5113 2.4891 23.6841
HCC1419 CTRP2 2.5161 3.7553 2.5139 23.5134
MDA-MB-453 CTRP2 2.5907 4.1539 2.5797 23.046
HCC202 CTRP2 2.5954 5.0655 2.4953 23.3183
HCC38 CTRP2 2.6729 4.9459 2.5963 22.721
UACC-812 CTRP2 2.7061 4.1128 2.6992 22.2631
T-47D CTRP2 3.5384 5.4149 3.4521 16.9899
CAL-51 CTRP2 3.6194 5.8744 3.4424 16.7706
Hs 578T CTRP2 3.7082 5.7573 3.5671 16.052
CAL-85-1 CTRP2 3.7937 6.3308 3.5044 16.018
HCC1143 CTRP2 3.8456 6.6895 3.4421 16.0968
ZR-75-30 CTRP2 4.0334 6.0046 3.8605 14.0011
MDA-MB-468 CTRP2 4.2344 6.8912 3.7871 13.6852
BT-474 CTRP2 5.8144 6.6243 5.5459 2.5859
MDA-MB-231 CTRP2 6.0206 11.5513 3.2711 11.6598
BT147 CTRP2 1.1169 3.1139 1.1089 32.8543
BT 172 CTRP2 1.5576 2.7253 1.5574 29.8924
BT 416 CTRP2 1.8725 3.4939 1.8674 27.8109
BT 504 CTRP2 2.1103 3.3814 2.109 26.2136
BT 112 CTRP2 2.475 3.0921 2.475 23.7799
BT 145 CTRP2 2.4839 3.1203 2.4839 23.7207
BT 286 CTRP2 2.5388 3.0967 2.5388 23.3549
BT 228 CTRP2 2.5647 3.0848 2.5647 23.1821
BT 131 CTRP2 2.6162 3.1581 2.6162 22.8394
BT 271 CTRP2 2.6806 3.2757 2.6806 22.4103
BT 216 CTRP2 2.7087 4.4685 2.6842 22.3049
BT164 CTRP2 2.7361 3.268 2.7361 22.0403
BT 239 CTRP2 2.7989 3.4472 2.7989 21.6217
BT 245 CTRP2 2.8777 4.0728 2.8745 21.1074
BT 422 CTRP2 2.9323 4.1518 2.9282 20.7469
BT 139 CTRP2 3.3995 4.9735 3.3647 17.7381
BT 231 CTRP2 3.4067 5.1859 3.3466 17.7765
BT 440 CTRP2 3.9031 6.2678 3.6429 15.1846
BT 482 CTRP2 3.9382 5.9932 3.7597 14.6547
BT 179 CTRP2 4.1139 5.2634 4.0884 12.9473
BT 340 CTRP2 4.1306 5.4312 4.0856 12.9027
BT 232 CTRP2 4.3959 6.6083 4.065 12.1747
BT 498 CTRP2 4.6654 6.3779 4.4367 10.0045
BT 224 CTRP2 4.7845 5.8761 4.7114 8.646
BT 159 CTRP2 4.8881 5.9982 4.7948 8.0283
BT 328 CTRP2 5.1277 6.2849 4.9694 6.6739
BT 359 CTRP2 5.1447 6.5054 4.907 6.8611
BT 444 CTRP2 5.3115 6.4214 5.1174 5.591
BT 333 CTRP2 5.3761 7.3067 4.7962 6.6969
BT 320 CTRP2 5.9351 6.5215 5.7096 1.6333
⏷ Show the Full List of 58 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KNS-60 CTRP2 1.3174 2.0534 1.3174 31.492
SF539 CTRP2 2.3706 3.0473 2.3706 24.4753
D283 Med CTRP2 2.7836 4.1384 2.7774 21.7446
Hs 683 CTRP2 2.8172 5.1658 2.7176 21.8396
SW1088 CTRP2 3.234 6.5583 2.823 20.1821
GOS-3 CTRP2 3.5178 5.9806 3.3042 17.5776
SF268 CTRP2 3.5996 6.4757 3.2471 17.54
YH-13 CTRP2 3.6176 6.8295 3.1466 17.8607
U-118MG CTRP2 3.9437 6.1937 3.7094 14.8202
CCF-STTG1 CTRP2 4.2114 6.0711 4.0366 12.8239
TM-31 CTRP2 4.2457 5.5721 4.1873 12.1826
KNS-42 CTRP2 4.2624 6.3198 4.018 12.7388
DK-MG CTRP2 4.2882 5.7325 4.203 11.9931
M059K CTRP2 4.2991 5.5415 4.2497 11.7956
GMS-10 CTRP2 4.5358 6.0392 4.3994 10.5277
Becker CTRP2 4.5617 6.9612 4.1084 11.5433
42-MG-BA CTRP2 4.674 6.2481 4.4886 9.7872
KNS-81 CTRP2 4.7166 8.0878 3.7796 12.4352
U-251MG CTRP2 4.857 6.7079 4.522 9.1367
SW1783 CTRP2 4.9555 9.625 3.2817 13.8805
SNB-75 CTRP2 5.2255 8.0649 4.2908 9.1203
GaMG CTRP2 5.2865 6.5332 5.0467 5.9316
KALS-1 CTRP2 5.2951 7.2464 4.7439 7.6355
KG-1-C CTRP2 5.6114 9.2526 4.0665 9.1875
DBTRG-05MG CTRP2 5.6218 6.6448 5.3464 4.1532
T98G CTRP2 5.7114 11.2414 3.1634 12.719
A-172 CTRP2 5.7187 10.9966 3.2919 12.1784
YKG-1 CTRP2 5.8469 8.6377 4.5797 6.5489
8-MG-BA CTRP2 6.2115 8.0934 5.1557 3.4253
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EFE-184 CTRP2 -1.9651 94.8519 -45.1988 50.2855
AN3-CA CTRP2 2.7444 4.0372 2.7401 21.9992
JHUEM-3 CTRP2 2.9027 7.5425 2.1155 23.745
ESS-1 CTRP2 2.9435 4.538 2.9235 20.7256
HEC-1-A CTRP2 3.0337 5.0798 2.963 20.2974
JHUEM-1 CTRP2 3.2194 5.2214 3.1408 19.0881
JHUEM-7 CTRP2 3.8015 6.0421 3.5973 15.6569
EN CTRP2 4.3653 5.5176 4.3243 11.3254
HEC-151 CTRP2 4.5537 5.2892 4.546 9.957
MFE-296 CTRP2 4.6719 6.7948 4.291 10.5367
HEC-50B CTRP2 4.7972 6.7436 4.4443 9.6009
MFE-319 CTRP2 4.891 6.3535 4.6895 8.4061
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR14TKB CTRP2 1.075 3.1839 -2.6291 0.576
UO-31 CTRP2 2.0512 4.5028 1.9906 26.8076
Caki-1 CTRP2 3.6594 5.3488 3.5931 16.1148
CAL-54 CTRP2 3.7222 5.679 3.5997 15.8931
VMRC-RCW CTRP2 3.8016 5.7627 3.6676 15.405
KMRC-3 CTRP2 3.9971 6.2181 3.7604 14.4737
TUHR10TKB CTRP2 4.2738 5.916 4.1456 12.2414
VMRC-RCZ CTRP2 4.2815 5.687 4.205 12.0073
786-O CTRP2 4.4172 5.633 4.3616 11.0304
KMRC-2 CTRP2 4.4434 4.8936 4.4432 10.6666
KMRC-1 CTRP2 4.9915 6.2085 4.8467 7.5281
ACHN CTRP2 5.1726 8.2083 4.1714 9.7344
Caki-2 CTRP2 5.4021 8.2405 4.3739 8.3681
RCC10RGB CTRP2 6.0039 6.8204 5.6221 1.8546
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GP2d CTRP2 -0.5407 1.5469 -0.5426 43.8764
CCK-81 CTRP2 1.1056 3.9367 1.051 33.0836
SNU-61 CTRP2 1.4933 3.5723 1.478 30.3711
LS123 CTRP2 2.339 3.38 2.3386 24.6874
HCT 15 CTRP2 2.3735 4.3294 2.3452 24.5509
T84 CTRP2 2.4923 4.6256 2.4435 23.829
SNU-C5 CTRP2 2.697 5.0369 2.6089 22.6001
CW-2 CTRP2 2.7522 4.926 2.6837 22.1653
SW1417 CTRP2 2.8832 5.4153 2.7436 21.5391
C2BBe1 CTRP2 2.9995 5.34 2.8838 20.6812
COLO 678 CTRP2 3.0621 5.4775 2.9251 20.3391
SW948 CTRP2 3.2196 6.8034 2.7254 20.5837
MDST8 CTRP2 3.2723 4.9454 3.2334 18.5994
NCI-H716 CTRP2 3.3163 5.4073 3.2137 18.5258
COLO201 CTRP2 3.4141 4.9856 3.3789 18.9495
SNU-407 CTRP2 3.4165 5.591 3.2863 17.9555
SNU-1033 CTRP2 3.4439 7.0432 2.8823 19.3495
RCM-1 [Human ESC] CTRP2 3.7161 5.4417 3.639 15.7743
LS1034 CTRP2 3.7734 5.3667 3.7127 15.3363
HCC-56 CTRP2 3.9877 5.1835 3.9633 13.7842
SW620 CTRP2 4.1668 5.6466 4.0886 12.777
COLO 320 CTRP2 4.1847 6.5479 3.858 13.5602
LoVo CTRP2 4.5671 7.428 3.9205 12.2603
NCI-H508 CTRP2 4.5824 6.3382 4.3599 11.3131
HCT 8 CTRP2 4.725 5.7515 4.6726 8.9696
CL-11 CTRP2 4.7532 7.4459 4.1048 11.0442
HT-55 CTRP2 4.7736 5.7035 4.7336 8.6027
RKO CTRP2 4.8022 6.1548 4.6571 9.4389
SNU-C1 CTRP2 4.8471 5.7641 4.8022 8.1302
KM12 CTRP2 5.2758 6.3005 5.124 6.0873
SNU-C4 CTRP2 5.3034 6.315 5.1484 5.4961
SNU-503 CTRP2 5.4452 6.6468 5.1652 5.0428
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-5 CTRP2 2.2027 4.6386 2.1354 25.8212
HLF CTRP2 2.4049 4.2298 2.3844 24.3157
JHH-2 CTRP2 2.6548 3.84 2.6528 22.5886
PLC/PRF/5 CTRP2 2.7419 4.2547 2.7307 22.0392
SNU-475 CTRP2 3.3064 4.7011 3.2896 18.297
SNU-761 CTRP2 3.409 5.0321 3.3684 17.6947
HuH-6 CTRP2 3.6574 5.6715 3.5309 16.3387
SNU-398 CTRP2 3.9419 6.069 3.7431 14.7035
SNU-449 CTRP2 4.1297 6.0441 3.9549 13.3674
JHH-4 CTRP2 4.207 5.3061 4.1822 12.3244
JHH-1 CTRP2 4.4119 4.9638 4.4112 10.8782
SNU-423 CTRP2 4.8426 6.4541 4.6018 8.8741
SK-HEP-1 CTRP2 5.0375 6.9566 4.61 8.3044
SNU-387 CTRP2 5.3512 6.3093 5.202 5.1576
JHH-6 CTRP2 5.5961 5.8718 5.5893 3.0096
HuH-1 CTRP2 5.606 7.23 5.0558 5.0867
SNU-886 CTRP2 6.2494 8.0938 3.4743 0.4717
Hep-G2 CTRP2 7.1607 12.6262 3.6311 8.1565
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 98 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2228 CTRP2 -0.2822 3.606 -0.3786 42.3873
NCI-H1703 CTRP2 0.2764 2.7139 0.2642 38.4661
LC-1F CTRP2 0.4259 13.6284 -7.8537 27.8163
DMS 53 CTRP2 0.7148 3.0709 0.7 35.5553
NCI-H2087 CTRP2 0.8051 4.7289 0.6246 35.4716
HCC1195 CTRP2 1.338 4.4277 1.2424 31.6725
DV-90 CTRP2 1.3888 4.3972 1.3004 31.3106
NCI-H1666 CTRP2 1.5056 4.3251 1.433 30.4811
SK-LU-1 CTRP2 1.5219 4.541 1.4233 30.4596
Sq-1 CTRP2 1.5304 3.3956 1.5221 30.1004
NCI-H23 CTRP2 1.6102 5.0732 1.4316 30.14
NCI-H1755 CTRP2 1.6302 8.2122 0.5002 32.9525
NCI-H1341 CTRP2 1.7467 3.6004 1.7364 28.6664
Calu-1 CTRP2 1.7471 3.5018 1.7398 28.6533
NCI-H2286 CTRP2 1.8323 4.7604 1.7239 30.5306
NCI-H841 CTRP2 1.8477 3.9088 1.8266 28.0297
HCC4006 CTRP2 1.9028 4.1815 1.8652 27.718
NCI-H889 CTRP2 1.9337 4.1732 1.8982 27.5051
EBC-1 CTRP2 1.9636 4.9637 1.8326 27.6308
NCI-H2141 CTRP2 2.0318 7.5399 1.182 29.5956
NCI-H1563 CTRP2 2.1433 4.9715 2.0246 26.3925
LOU-NH91 CTRP2 2.1653 3.6025 2.1618 25.8548
DMS 454 CTRP2 2.1877 5.8545 1.8858 26.7308
NCI-H146 CTRP2 2.2189 3.7443 2.2133 25.5049
NCI-H1395 CTRP2 2.2745 6.6841 1.7393 26.9674
NCI-H522 CTRP2 2.2894 5.2244 2.1377 25.5338
NCI-H1693 CTRP2 2.3765 3.5743 2.3751 24.4407
NCI-H1650 CTRP2 2.3815 4.163 2.364 24.4616
NCI-H810 CTRP2 2.4397 3.2062 2.4397 24.015
NCI-H1105 CTRP2 2.4505 3.376 2.4503 23.9439
NCI-H2196 CTRP2 2.496 3.3252 2.496 23.6398
NCI-H1092 CTRP2 2.5045 3.5992 2.5037 23.586
NCI-H1694 CTRP2 2.5134 3.9198 2.5083 23.5408
NCI-H2085 CTRP2 2.5292 3.9472 2.5237 23.437
NCI-H2029 CTRP2 2.5486 3.2104 2.5486 23.2894
T3M-10 CTRP2 2.5537 4.9321 2.4709 23.5363
COLO 668 CTRP2 2.5589 5.1555 2.4412 23.622
NCI-H226 CTRP2 2.6097 3.0853 2.6097 22.8825
HOP-62 CTRP2 2.6168 5.133 2.5074 23.2082
ChaGo-K-1 CTRP2 2.6254 4.8304 2.561 22.9955
COR-L95 CTRP2 2.6697 4.3365 2.6521 22.5417
NCI-H2081 CTRP2 2.6736 7.5983 1.8493 25.3706
NCI-H322 CTRP2 2.6749 4.1617 2.6657 22.4787
LXF 289 CTRP2 2.7845 6.0683 2.4803 22.7789
NCI-H1355 CTRP2 2.7989 6.0566 2.4991 22.6675
NCI-H1184 CTRP2 2.8705 5.9352 2.6098 22.0518
COR-L51 CTRP2 3.0463 4.869 3.0028 20.1206
NCI-H524 CTRP2 3.1503 16.6743 -1.8403 33.8254
NCI-H446 CTRP2 3.2027 5.2962 3.1107 19.2458
NCI-H1435 CTRP2 3.2226 8.03 2.2627 43.6494
HCC2935 CTRP2 3.2806 5.6306 3.1302 18.9312
NCI-H1623 CTRP2 3.2843 7.9591 2.3566 21.7682
NCI-H520 CTRP2 3.2877 5.2902 3.2032 18.6533
NCI-H1869 CTRP2 3.3477 6.0795 3.0917 18.8619
HOP-92 CTRP2 3.3944 5.8024 3.2148 18.2773
NCI-H1568 CTRP2 3.4307 5.0751 3.3865 17.5621
NCI-H1915 CTRP2 3.4374 6.0065 3.2095 18.164
DMS 273 CTRP2 3.4715 5.8574 3.2853 17.7875
NCI-H460 CTRP2 3.548 6.1567 3.2885 18.8423
NCI-H2444 CTRP2 3.5485 5.4449 3.4577 16.9383
SW1271 CTRP2 3.5551 6.1416 3.3006 17.4776
NCI-H2170 CTRP2 3.5573 6.1806 3.2918 17.5028
NCI-H1944 CTRP2 3.5588 7.4757 2.8407 19.1803
NCI-H838 CTRP2 3.6238 5.3856 3.5491 16.3811
Calu-6 CTRP2 3.6435 6.15 3.3946 16.8694
A-549 CTRP2 3.6482 5.7182 3.5107 16.4387
NCI-H647 CTRP2 3.6613 6.0688 3.437 16.6619
NCI-H2342 CTRP2 3.7745 6.3911 3.4646 16.2216
VMRC-LCD CTRP2 3.79 5.587 3.6922 15.3549
SK-MES-1 CTRP2 3.934 6.2701 3.6759 14.9714
IA-LM CTRP2 4.0691 5.3253 4.0341 13.278
NCI-H1793 CTRP2 4.1183 6.5632 3.7809 14.0405
NCI-H441 CTRP2 4.1444 6.0267 3.9757 14.2292
NCI-H2126 CTRP2 4.1712 6.5737 3.8345 13.6871
NCI-H661 CTRP2 4.2302 5.7178 4.1432 12.3857
COR-L105 CTRP2 4.2403 6.1598 4.0429 12.7138
RERF-LC-MS CTRP2 4.2656 5.4198 4.2312 11.9668
RERF-LC-Ad2 CTRP2 4.4316 6.6821 4.0767 12.0287
NCI-H1339 CTRP2 4.4986 6.8541 4.0834 11.8145
HCC1438 CTRP2 4.5765 8.1656 3.6034 13.4938
PC-14 CTRP2 4.578 5.6429 4.5331 9.9226
NCI-H1373 CTRP2 4.5942 5.6168 4.5547 10.5215
LCLC-97TM1 CTRP2 4.6846 7.5045 4.0087 12.4632
NCI-H2172 CTRP2 4.7203 6.8159 4.3342 10.9952
NCI-H2023 CTRP2 4.7669 8.3243 3.7204 12.5484
SW1573 CTRP2 4.8041 5.8968 4.7281 8.526
NCI-H1792 CTRP2 5.1486 5.9173 5.0983 6.5967
LUDLU-1 CTRP2 5.1696 12.3084 2.1565 17.8357
EPLC-272H CTRP2 5.277 6.8258 4.9141 6.475
NCI-H2110 CTRP2 5.2852 7.9486 4.4039 8.5158
DMS 114 CTRP2 5.3424 6.4366 5.1443 5.4018
NCI-H1651 CTRP2 5.4941 8.4214 4.3711 8.1729
LK2 CTRP2 5.5482 5.9344 5.5285 3.373
KNS-62 CTRP2 5.5705 6.0479 5.5263 3.312
LC-1/sq-SF CTRP2 5.6051 7.1202 5.1075 4.877
EKVX CTRP2 6.6466 11.6607 3.721 8.6477
Lu-65 CTRP2 8.2158 20.8905 0.3441 18.1751
Hs 888.Lu CTRP2 4.0739 6.3881 3.7911 14.133
⏷ Show the Full List of 98 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 2.5611 2.9571 2.5611 23.2062
SYO-1 CTRP2 5.4381 6.6134 5.1722 5.0338
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 3.7091 5.6266 3.5965 15.9451
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 4.644 7.2114 4.0924 11.382
TOV-21G CTRP2 -1.8254 1.3544 -1.838 52.4027
OC 314 CTRP2 0.2427 2.8216 0.2261 38.7042
A2780 CTRP2 0.9084 2.1079 0.9084 36.7524
OV7 CTRP2 1.4881 4.6957 1.3647 30.7671
OVCAR-5 CTRP2 2.0285 4.378 1.9796 26.9187
TYK-nu CTRP2 2.3494 3.311 2.3492 24.6171
OVK18 CTRP2 2.5334 4.8547 2.4599 23.6396
Caov-3 CTRP2 2.5759 5.8002 2.3229 23.983
TOV-112D CTRP2 2.7144 4.0444 2.7095 22.2011
JHOS-2 CTRP2 3.26 6.147 2.977 19.5426
COV434 CTRP2 3.626 6.3545 3.3144 17.2141
COV362 CTRP2 3.6332 5.9217 3.4454 16.7173
OV-90 CTRP2 3.6994 4.988 3.6782 15.694
COV644 CTRP2 4.184 6.6929 3.8062 13.7562
EFO-27 CTRP2 4.2381 5.737 4.1478 12.3444
OV56 CTRP2 4.3232 6.1927 4.1235 12.171
OAW42 CTRP2 4.5752 5.6287 4.5324 9.9337
HEY A8 CTRP2 4.6139 6.0002 4.4951 9.9445
FU-OV-1 CTRP2 4.6515 7.4289 4.0075 11.6949
JHOM-1 CTRP2 4.7234 6.5417 4.4419 9.8178
OVCAR-4 CTRP2 4.9011 5.8967 4.8337 8.4312
IGROV-1 CTRP2 5.012 6.9411 4.5901 8.4505
MCAS CTRP2 5.2152 6.1927 5.095 5.9513
RMG-I CTRP2 5.2305 11.7423 2.4917 16.419
SNU-840 CTRP2 5.3996 7.1402 4.8969 6.2318
EFO-21 CTRP2 5.4874 6.3417 5.3357 4.2652
OAW28 CTRP2 6.3084 8.9917 4.7845 4.8076
OVCAR-8 CTRP2 6.5521 8.7021 5.1112 3.2701
SK-OV-3 CTRP2 11.0372 22.7799 1.3815 10.9652
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 5.2242 6.4953 4.9956 6.3004
Aska-SS CTRP2 5.553 6.6792 5.2613 4.3818
MES-SA CTRP2 -0.7731 1.3684 -0.7749 45.4237
A-204 CTRP2 0.2077 3.465 0.151 39.0555
G-401 CTRP2 1.6009 3.1735 1.598 29.613
TE 617.T CTRP2 1.9873 4.9408 1.8619 27.4536
KYM-1 CTRP2 1.996 3.1474 1.9955 26.9728
GCT CTRP2 2.4503 3.4132 2.4501 23.9452
G-402 CTRP2 2.6036 5.1772 2.4857 23.3253
Rh18 CTRP2 2.6312 4.124 2.6224 24.4559
TE 441.T CTRP2 2.7797 3.6203 2.7796 21.7501
HT-1080 CTRP2 3.1447 4.7126 3.1206 19.3993
Tm87-16 CTRP2 3.5987 6.3037 3.3002 17.3477
SK-UT-1 CTRP2 3.6379 6.2079 3.3718 16.969
SK-LMS-1 CTRP2 3.7633 5.2466 3.7188 15.3478
RD CTRP2 3.86 6.7041 3.4525 16.0162
RKN CTRP2 4.364 5.5741 4.3142 11.3645
SW982 CTRP2 4.3737 6.7642 3.984 12.5441
Hs 729.T CTRP2 4.3917 7.7158 3.6151 13.9245
TTC-709 CTRP2 4.687 6.6468 4.3639 10.2164
BT-16 CTRP2 5.2741 7.118 4.7815 7.0103
BT-12 CTRP2 5.424 5.873 5.4053 4.1967
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 CTRP2 2.6311 4.9011 2.5578 22.9882
NCI-H2052 CTRP2 4.3024 6.5917 3.97 12.8005
IST-Mes1 CTRP2 4.4797 6.9424 4.0289 12.0756
MPP 89 CTRP2 4.4818 6.839 4.0713 11.9077
JL-1 CTRP2 5.7648 12.1857 2.7377 14.3228
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 CTRP2 2.38 5.195 2.2411 24.8867
PaCa-3 CTRP2 2.9269 4.8761 2.8756 20.9428
LNCaP clone FGC CTRP2 3.4958 5.1224 3.4499 17.1345
VCaP CTRP2 4.5082 5.9201 4.4001 10.6096
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 4.1658 6.1642 3.9603 13.2384
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 0.6842 2.8149 0.6765 35.7358
HGC-27 CTRP2 1.4182 3.1179 1.4143 30.8334
ECC10 CTRP2 2.6279 4.1071 2.6195 22.7893
Hs 746.T CTRP2 3.0581 4.4958 3.0446 19.9401
SNU-1 CTRP2 3.2827 5.0038 3.2379 18.5499
HuG1-N CTRP2 3.2865 5.3501 3.1918 18.6968
Fu97 CTRP2 3.3635 4.9591 3.3282 17.9796
KE-39 CTRP2 3.5003 4.9184 3.4757 17.0316
MKN7 CTRP2 3.5697 5.1271 3.5278 16.6281
SNU-216 CTRP2 4.3099 5.9467 4.1773 12.0167
KATO III CTRP2 4.3956 5.9455 4.271 11.418
IM95 CTRP2 4.4373 8.4596 3.3298 14.9376
NUGC-3 CTRP2 4.4981 8.4368 3.4011 14.4998
SNU-601 CTRP2 4.5423 6.5663 4.238 11.1042
MKN74 CTRP2 4.7607 7.0517 4.2812 10.3312
LMSU CTRP2 4.7787 6.1113 4.6443 8.9046
SH-10-TC CTRP2 5.3731 6.3033 5.2277 4.9979
SNU-685 CTRP2 4.3842 6.361 4.1372 11.9395
SNG-M CTRP2 5.3506 6.276 5.2134 5.1164
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FTC-133 CTRP2 0.5756 2.3485 0.5737 36.4403
SW579 CTRP2 2.2876 3.7429 2.2831 25.0435
ML-1 [Human leukemia] CTRP2 2.9864 6.9409 2.4255 22.3707
FTC-238 CTRP2 4.3438 5.452 4.3103 11.4429
TT2609-C02 CTRP2 5.2419 7.7088 4.4757 8.3257
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FaDu CTRP2 2.4376 3.6978 2.4355 24.0361
PE/CA-PJ41 (clone D2) CTRP2 2.7089 4.9995 2.6271 22.4993
HSC-2 CTRP2 2.7898 3.3739 2.7898 21.6828
PE/CA-PJ15 CTRP2 3.0618 5.1534 2.9823 20.1407
PE/CA-PJ49 CTRP2 3.4036 4.7995 3.384 17.6592
SCC-4 CTRP2 3.757 5.3502 3.6977 15.4407
PE/CA-PJ34 (clone C12) CTRP2 4.0879 5.6381 4.0049 13.3189
CAL-27 CTRP2 4.4769 5.7328 4.4077 10.6803
SCC-25 CTRP2 4.5226 7.3725 3.8979 13.3908
BICR 6 CTRP2 4.5748 5.7083 4.5182 9.9842
SCC-9 CTRP2 4.5891 6.3901 4.35 10.5496
BICR 22 CTRP2 4.7526 6.9643 4.3087 10.2464
YD-8 CTRP2 4.7807 6.8816 4.3719 9.9252
HSC-4 CTRP2 4.8545 5.9178 4.7781 8.1918
CAL-33 CTRP2 5.0593 9.5723 3.4046 13.1415
BICR 31 CTRP2 5.6918 7.1498 5.176 4.393
BICR 18 CTRP2 5.7541 7.1143 5.2518 3.9378
BICR 56 CTRP2 6.0616 6.9666 5.5975 1.8455
BICR 16 CTRP2 6.8625 16.0852 1.6885 16.1536
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1197 CTRP2 1.75 2.8099 1.7498 28.6106
SCaBER CTRP2 3.0293 4.27 3.0239 20.1052
J82 CTRP2 3.2376 6.5797 2.82 20.1824
T24 CTRP2 3.3221 5.7331 3.1523 18.7237
HT-1376 CTRP2 3.3511 5.7246 3.1859 18.5146
UM-UC-1 CTRP2 3.7032 5.3757 3.6359 15.8265
KMBC-2 CTRP2 4.4767 5.9799 4.3507 10.8833
BC-3C CTRP2 4.4898 5.7383 4.4206 10.5945
UM-UC-3 CTRP2 4.4963 5.5137 4.4647 10.4208
U-BLC1 CTRP2 4.7018 7.1014 4.1988 10.8115
647V CTRP2 4.8158 6.5564 4.5357 9.2002
RT-112 CTRP2 5.0488 5.7329 5.0243 7.2137
RT-4 CTRP2 5.4321 8.0729 4.4836 7.8466
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 6.2161 7.8962 5.2574 2.9912

References

1 Deubiquitylating enzymes and drug discovery: emerging opportunities. Nat Rev Drug Discov. 2018 Jan;17(1):57-78.