Details of the Drug

General Information of Drug (ID: DMWA5XP)

Drug Name
KU-60019
Synonyms
KU-60019; 925701-49-1; ku60019; 925701-46-8; KU 60019; UNII-IAN358A69K; IAN358A69K; CHEMBL2140173; 2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-N-[5-(6-morpholin-4-yl-4-oxopyran-2-yl)-9H-thioxanthen-2-yl]acetamide; C30H33N3O5S; 2-((2S,6R)-2,6-dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide; 2-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]-N-{5-[6-(morpholin-4-yl)-4-oxo-4H-pyran-2-yl]-9H-thioxanthen-2-yl}acetamide; MLS006011020; cc-509; SCHEMBL3681453; GTPL8041; EX-A658; DTXSID00580453; AOB3627
Indication
Disease Entry ICD 11 Status REF
Non-small-cell lung cancer 2C25.Y Clinical trial [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 547.7
Logarithm of the Partition Coefficient (xlogp) 3.5
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C30H33N3O5S
IUPAC Name
2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-N-[5-(6-morpholin-4-yl-4-oxopyran-2-yl)-9H-thioxanthen-2-yl]acetamide
Canonical SMILES
C[C@@H]1CN(C[C@@H](O1)C)CC(=O)NC2=CC3=C(C=C2)SC4=C(C3)C=CC=C4C5=CC(=O)C=C(O5)N6CCOCC6
InChI
InChI=1S/C30H33N3O5S/c1-19-16-32(17-20(2)37-19)18-28(35)31-23-6-7-27-22(13-23)12-21-4-3-5-25(30(21)39-27)26-14-24(34)15-29(38-26)33-8-10-36-11-9-33/h3-7,13-15,19-20H,8-12,16-18H2,1-2H3,(H,31,35)/t19-,20+
InChIKey
SCELLOWTHJGVIC-BGYRXZFFSA-N
Cross-matching ID
PubChem CID
15953870
CAS Number
925701-49-1
TTD ID
D02NUT
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ATM serine/threonine kinase (ATM) TTKBM7V ATM_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Non-small-cell lung cancer
ICD Disease Classification 2C25.Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
ATM serine/threonine kinase (ATM) DTT ATM 8.10E-01 -0.01 -0.02
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 3.0856 5.846 1.8579 12.3996
NOS-1 [Human HNSCC] GDSC1 1.9786 3.9613 1.6425 19.0801
ES1 GDSC1 2.5918 5.9592 1.3544 18.2146
ES7 GDSC1 2.7664 5.4544 1.7635 14.4278
HuO9 GDSC1 2.998 5.297 2.053 11.2375
ES8 GDSC1 3.2872 6.8116 1.548 13.977
ES4 GDSC1 3.3543 4.5742 2.7225 4.6112
H-EMC-SS GDSC1 3.7116 6.013 2.2857 6.8604
EW-16 GDSC1 3.7223 5.5553 2.5188 5.0225
EW-22 GDSC1 3.7406 7.823 1.41 13.3802
CAL-72 GDSC1 3.7771 6.1303 2.2767 6.7296
CHSA8926 GDSC1 3.7836 5.843 2.4224 5.5859
U2OS GDSC1; CTRP2 3.8801 8.0819 2.9284 17.9641
CHSA0108 GDSC1 3.8965 8.1635 1.3617 13.2083
EW-18 GDSC1 3.9029 6.1437 2.361 5.7128
MHH-ES-1 GDSC1; CTRP2 3.9544 6.8565 3.4996 15.568
ES5 GDSC1 3.9816 6.6383 2.1762 6.8968
NY GDSC1 4.0052 7.0936 1.9708 8.3857
HuO-3N1 GDSC1 4.1049 6.4305 2.3618 5.1585
EW-1 GDSC1 4.1829 7.203 2.0436 7.3302
A-673 GDSC1; CTRP2 4.1979 6.3562 3.9363 13.2309
ES6 GDSC1 4.2306 7.5675 1.9005 8.2627
TC-71 GDSC1 4.2688 7.0812 2.1608 6.2283
EW-7 GDSC1 4.3085 6.5994 2.4143 4.2725
SJSA-1 GDSC1; CTRP2 4.7148 9.5792 3.0754 17.5972
SK-ES-1 GDSC1; CTRP2 4.8405 6.9307 4.4149 9.5954
CAL-78 GDSC1; CTRP2 5.0384 7.5509 4.3476 9.3455
CADO-ES1 GDSC1 5.0664 7.0124 2.6483 1.4457
EW-11 GDSC1 5.275 7.4779 2.5579 1.6697
SaOS-2 GDSC1; CTRP2 5.3662 8.1442 4.3869 8.3966
EW-24 GDSC1 5.381 6.6419 2.9163 0.1956
HOS GDSC1; CTRP2 5.6543 7.9946 4.7278 6.3362
CHSA0011 GDSC1 5.7937 8.386 2.4337 1.7096
EW-13 GDSC1 6.0603 7.6511 2.8119 0.2038
TC71 CTRP2 6.0743 7.2546 5.464 2.3822
SW1353 CTRP2 6.1332 11.2723 3.5041 10.4832
MG-63 GDSC1; CTRP2 6.2838 9.206 4.6584 5.38
EW-3 GDSC1 6.2952 20.1055 -2.7393 25.416
SK-N-MC CTRP2 6.4171 10.0552 4.3405 6.4732
Hs 888.T CTRP2 6.938 9.512 4.9869 2.9872
Hs 822.T CTRP2 7.2062 8.0724 5.7609 0.1344
G-292 clone A141B1 GDSC1; CTRP2 7.5025 13.6315 3.3867 8.6011
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 212 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 3.6701 6.2451 3.3958 16.7849
MEC1 CTRP2 4.6796 8.8847 3.3721 14.1675
JM1 GDSC1; CTRP2 4.5373 7.3936 3.9042 12.4032
HuT 78 CTRP2 0.6791 18.1404 -4.9012 43.7583
Pfeiffer CTRP2 1.2052 5.0493 0.9978 32.9158
SUP-T11 CTRP2 1.2454 4.0673 1.1856 32.1699
ALL-PO GDSC1 1.4297 3.8729 1.084 25.9238
OCI-Ly7 GDSC1 1.4809 3.1126 1.3658 23.7576
RPMI-8866 GDSC1 1.6263 4.5306 1.0432 25.0986
ATN-1 GDSC1 1.7885 4.28 1.3158 22.3806
WSU-NHL GDSC1 1.9794 4.1252 1.5796 19.5206
SKM-1 GDSC1; CTRP2 2.0356 4.6956 1.9503 26.9954
Ri-1 CTRP2 2.059 5.163 1.9001 27.0915
Karpas-231 GDSC1 2.1108 3.7658 1.8571 16.8567
KMS-34 CTRP2 2.1892 3.6122 2.1858 25.6952
HAL-01 GDSC1 2.1999 4.0948 1.8251 16.6169
GR-ST GDSC1 2.2252 6.9793 0.5146 25.3702
SU-DHL-5 GDSC1 2.2272 3.8122 1.9649 15.4711
EoL-1 GDSC1 2.3058 4.3499 1.8282 16.0593
Ramos.2G6.4C10 GDSC1 2.3099 6.217 0.9637 22.1874
MHH-PREB-1 GDSC1 2.3147 4.3488 1.8379 15.9436
NU-DUL-1 GDSC1; CTRP2 2.3153 4.1588 2.1335 14.3101
MOLM-16 GDSC1; CTRP2 2.4487 4.6942 2.3898 24.1538
NKM-1 GDSC1 2.5106 7.1999 0.6713 23.1377
BL-70 CTRP2 2.5539 4.4027 2.5277 23.3422
SUP-M2 GDSC1; CTRP2 2.5619 3.9258 2.5574 23.2157
DG-75 GDSC1 2.5829 5.3527 1.6399 16.1595
P30/OHK GDSC1 2.5846 5.4702 1.585 16.5607
SUP-B8 GDSC1 2.5918 4.5261 2.0395 13.1085
BE-13 GDSC1 2.6258 5.3987 1.6586 15.8292
KMS-12-BM GDSC1; CTRP2 2.6303 5.1152 2.5249 23.1044
SU-DHL-6 GDSC1; CTRP2 2.6325 5.3414 2.4865 23.2305
DND-41 GDSC1; CTRP2 2.6639 5.1194 2.5603 22.8744
Karpas-45 GDSC1 2.6901 4.3495 2.2189 11.2947
CTV-1 GDSC1 2.7276 4.1069 2.3671 10.0017
KMOE-2 GDSC1 2.7826 5.276 1.8657 13.5798
Peer CTRP2 2.7858 4.5725 2.7567 21.8071
KMS-21-BM CTRP2 2.7923 4.2892 2.7809 21.7038
697 GDSC1; CTRP2 2.8046 4.7183 2.7633 21.7232
CRO-AP2 GDSC1 2.8638 4.6695 2.2365 10.3765
SU-DHL-1 CTRP2 2.8794 4.0643 2.8764 21.0955
BL-41 GDSC1 2.8973 3.8609 2.6496 7.0719
CCRF-CEM GDSC1 2.904 6.9941 1.1269 18.4939
L-540 GDSC1; CTRP2 2.905 4.8898 2.8508 21.0985
KCL-22 GDSC1; CTRP2 2.9087 4.8217 2.8625 21.0465
Mono-Mac-6 GDSC1 2.9093 5.8129 1.7178 14.1764
RCH-ACV GDSC1; CTRP2 2.9178 6.0498 2.6308 21.8319
NCI-H929 GDSC1; CTRP2 2.9324 5.1161 2.8492 21.0154
WSU-DLCL2 GDSC1; CTRP2 2.9535 4.7944 2.9126 20.7297
HH [Human lymphoma] GDSC1; CTRP2 2.9828 7.3871 2.26 22.9859
A4/Fukuda GDSC1; CTRP2 2.9848 5.371 2.8622 20.8034
RS4;11 GDSC1; CTRP2 3.0076 6.5995 2.5636 25.1698
MV4-11 GDSC1; CTRP2 3.0194 4.7659 2.9848 20.2694
JeKo-1 GDSC1; CTRP2 3.0278 6.0333 2.7554 21.0481
KMS-26 CTRP2 3.0502 4.2427 3.0459 19.9622
MLMA GDSC1 3.0716 5.1333 2.2 9.796
Daudi GDSC1; CTRP2 3.0823 5.0794 3.0149 19.9626
F-36P CTRP2 3.0894 4.9504 3.0391 19.8566
P32/ISH GDSC1 3.103 4.2517 2.664 6.0404
NALM-6 GDSC1; CTRP2 3.1085 4.974 3.0566 19.7349
EM-2 GDSC1; CTRP2 3.1145 4.9258 3.0687 19.6742
NCO2 CTRP2 3.1154 5.2625 3.0224 19.8307
QIMR-WIL GDSC1 3.1469 4.5952 2.5341 6.8772
Loucy GDSC1 3.1493 4.7108 2.4788 7.3019
NB4 GDSC1; CTRP2 3.1613 4.1535 3.1598 19.2126
SU-DHL-8 GDSC1; CTRP2 3.2031 6.6688 2.7531 20.5301
RPMI-8402 GDSC1; CTRP2 3.2232 4.6979 3.2034 18.8616
MOLM-13 GDSC1; CTRP2 3.2627 7.3695 2.5663 21.0487
JVM-3 GDSC1; CTRP2 3.2794 7.5437 2.517 21.1844
L-428 GDSC1; CTRP2 3.2942 6.1348 3.0179 19.2911
U-698-M GDSC1 3.2982 5.0057 2.4602 6.882
KE-37 GDSC1; CTRP2 3.3147 4.6283 3.3024 18.2267
Karpas-1106P GDSC1 3.3165 4.6565 2.6501 5.318
MOLM-6 CTRP2 3.3569 6.4878 2.9794 19.2431
DB GDSC1; CTRP2 3.3646 6.6776 2.9254 19.4194
Farage GDSC1 3.3668 4.6453 2.6973 4.7665
LAMA-84 GDSC1; CTRP2 3.3829 5.6876 3.2289 18.263
Jurkat GDSC1; CTRP2 3.3926 4.4051 3.3897 17.6763
EB1 CTRP2 3.437 6.4024 3.0936 18.5863
HEL GDSC1; CTRP2 3.4666 4.9468 3.4379 17.2704
OCI-AML-2 GDSC1; CTRP2 3.4757 5.4484 3.3784 17.446
TUR GDSC1 3.4975 4.6689 2.7886 3.6115
TALL-1 [Human adult T-ALL] CTRP2 3.5026 5.4117 3.414 17.2364
BV-173 GDSC1; CTRP2 3.5301 8.7737 2.2675 21.4219
SU-DHL-10 GDSC1; CTRP2 3.5304 5.8628 3.3481 17.3817
MOLT-4 GDSC1 3.531 6.0031 2.1513 8.4929
P12-Ichikawa GDSC1; CTRP2 3.5813 5.3017 3.5167 16.629
Ki-JK CTRP2 3.583 5.4305 3.4975 16.6901
GA-10 GDSC1; CTRP2 3.5913 5.8263 3.4235 16.925
HT GDSC1; CTRP2 3.5914 5.3307 3.523 16.5748
KM-H2 GDSC1; CTRP2 3.6079 5.9332 3.4149 16.9046
MY-M12 GDSC1 3.6113 6.532 1.9512 9.7742
JSC-1 GDSC1 3.6179 6.5582 1.9434 9.8126
M-07e CTRP2 3.6202 6.1944 3.3564 17.0782
Ku812 GDSC1; CTRP2 3.6225 5.8996 3.4394 16.7721
KY821 GDSC1 3.6681 5.4644 2.5237 5.1468
YT GDSC1 3.686 5.012 2.7577 3.2912
BC-1 GDSC1 3.6865 5.3157 2.6101 4.4232
NU-DHL-1 CTRP2 3.7362 6.3821 3.4256 16.4784
HC-1 GDSC1 3.7362 6.7271 1.951 9.3662
PL21 CTRP2 3.7551 5.9912 3.5604 15.9311
MC116 GDSC1; CTRP2 3.767 7.5349 3.0377 17.8512
JVM-2 GDSC1 3.7702 6.6018 2.0389 8.5837
MOLT-16 GDSC1; CTRP2 3.8031 5.5459 3.7143 15.2359
PL-21 GDSC1 3.807 6.9202 1.9093 9.4586
MOLP-8 GDSC1 3.8091 5.6584 2.5306 4.6812
ALL-SIL GDSC1; CTRP2 3.8308 5.0458 3.8109 14.8142
KMS-20 CTRP2 3.8505 5.8977 3.6886 15.1787
HDLM-2 GDSC1; CTRP2 3.8593 5.994 3.6733 15.2064
CML-T1 GDSC1; CTRP2 3.8721 5.6825 3.7618 14.8516
KMS-18 CTRP2 3.8724 7.0795 3.3284 16.4486
SR GDSC1; CTRP2 3.8738 5.9226 3.7077 15.0385
MEG-01 GDSC1 3.8832 5.7458 2.5398 4.4073
Karpas-299 GDSC1; CTRP2 3.8922 5.6104 3.7983 14.6603
Kasumi-2 CTRP2 3.9079 7.7868 3.0823 17.2942
JURL-MK1 GDSC1; CTRP2 3.9099 5.6519 3.8092 14.5667
KMS-11 GDSC1; CTRP2 3.9145 6.2462 3.6619 15.081
DEL GDSC1; CTRP2 3.9247 4.6639 3.9235 14.1256
OCI-AML-3 GDSC1; CTRP2 3.9581 6.1234 3.7455 14.6457
REC-1 CTRP2 3.962 8.3133 2.9125 17.8076
KE-97 CTRP2 4.003 5.9971 3.8294 14.206
SU-DHL-4 GDSC1; CTRP2 4.0049 6.1989 3.7746 14.3989
SUP-T1 GDSC1; CTRP2 4.0193 5.1921 3.9958 13.5704
PF-382 GDSC1; CTRP2 4.0374 6.2318 3.8002 14.2075
RPMI-8226 GDSC1; CTRP2 4.0626 5.85 3.9314 13.6577
AMO1 GDSC1; CTRP2 4.0738 4.748 4.0728 13.1315
Mino CTRP2 4.0765 6.9087 3.6113 14.7987
AML-193 CTRP2 4.0925 6.5588 3.7544 14.2144
GDM-1 GDSC1; CTRP2 4.1434 5.6598 4.0608 12.9481
OCI-Ly19 GDSC1; CTRP2 4.1465 7.0429 3.6351 14.5114
MOLT-13 GDSC1; CTRP2 4.1649 6.6322 3.8072 13.8073
CTB-1 GDSC1 4.1651 7.3327 1.9683 7.9421
P3HR-1 CTRP2 4.1775 8.6716 2.9721 17.0139
MHH-CALL-4 CTRP2 4.2098 5.7633 4.1114 12.5614
P31/FUJ GDSC1; CTRP2 4.2667 6.6085 3.9255 13.0701
Karpas-620 GDSC1; CTRP2 4.2722 6.7761 3.8707 13.261
KG-1 GDSC1 4.2943 6.8645 2.2807 5.2793
SEM CTRP2 4.2992 6.1504 4.1098 12.293
L-363 GDSC1; CTRP2 4.3439 7.1467 3.8037 13.3172
U266B1 CTRP2 4.344 7.159 3.7989 13.3356
Mono-Mac-1 CTRP2 4.3462 7.0191 3.8568 13.1066
SU-DHL-16 GDSC1 4.3568 8.1671 1.6982 9.3904
OPM-2 GDSC1; CTRP2 4.3632 6.1099 4.1914 11.8036
LC4-1 GDSC1 4.3742 6.6446 2.4341 3.9808
MHH-CALL-3 CTRP2 4.4001 6.3297 4.1646 11.7916
VAL GDSC1 4.402 6.5046 2.5152 3.351
Reh GDSC1; CTRP2 4.4048 6.9366 3.9515 12.5804
CESS GDSC1 4.4072 6.2644 2.6264 2.5827
KYO-1 CTRP2 4.4386 6.1415 4.2645 11.3106
SET-2 CTRP2 4.4627 6.7776 4.0743 11.9497
U-937 CTRP2 4.4831 6.129 4.3167 10.9866
ST486 GDSC1; CTRP2 4.5116 7.1004 3.9994 12.102
IM-9 GDSC1 4.5508 5.9594 2.8321 1.0992
K-562 GDSC1; CTRP2 4.5594 7.6263 3.8269 12.6493
NOMO-1 GDSC1; CTRP2 4.5835 9.9143 2.7889 16.7314
Granta-519 GDSC1; CTRP2 4.588 7.8868 3.7409 12.9162
THP-1 GDSC1; CTRP2 4.592 6.9395 4.1491 11.3031
EJM GDSC1; CTRP2 4.6097 7.3709 3.9892 11.8775
HPB-ALL CTRP2 4.6175 5.7133 4.5635 9.691
CA46 GDSC1; CTRP2 4.6637 6.7785 4.2887 10.5684
ML-2 GDSC1 4.6722 6.8167 2.5301 2.7285
Namalwa GDSC1; CTRP2 4.6862 6.4866 4.4216 10.001
SK-MM-2 GDSC1; CTRP2 4.7333 6.4507 4.4851 11.122
MOLP-2 CTRP2 4.8159 9.048 3.4268 13.6183
ME1 GDSC1 4.8241 6.1936 2.8625 0.67
JJN-3 GDSC1; CTRP2 4.8249 6.6308 4.5175 9.2436
OCI-Ly3 CTRP2 4.8399 10.4884 2.7531 16.2697
RL GDSC1; CTRP2 4.9038 9.2013 3.4376 13.3667
KMM-1 CTRP2 4.923 7.791 4.1221 10.5416
BALL-1 GDSC1 4.938 6.673 2.7252 1.1991
HuNS1 CTRP2 4.9444 8.7865 3.6754 12.302
Raji GDSC1; CTRP2 4.9578 7.2305 4.4093 9.3057
MOTN-1 CTRP2 4.9743 7.9091 4.1186 10.4282
MOLT-3 CTRP2 4.9822 5.6761 4.961 7.1483
KMS-27 CTRP2 5.0271 6.2086 4.8853 7.2808
A3/Kawakami GDSC1; CTRP2 5.0822 5.9181 5.0259 6.605
OCI-M1 GDSC1; CTRP2 5.0882 6.9515 4.6647 7.9552
TF-1 CTRP2 5.1036 7.8312 4.2826 9.4465
HD-MY-Z CTRP2 5.1938 6.5058 4.9592 6.5245
KO52 CTRP2 5.2444 6.8106 4.8869 6.6682
SUP-B15 GDSC1; CTRP2 5.2568 8.3276 4.1946 9.4416
MHH-CALL-2 GDSC1 5.274 6.8989 2.7834 0.6373
L-1236 GDSC1; CTRP2 5.278 8.7891 3.9906 10.2341
TK [Human B-cell lymphoma] GDSC1 5.2937 6.678 2.8716 0.3371
WIL2 NS GDSC1 5.3025 6.6037 2.9011 0.2566
HEL 92.1.7 CTRP2 5.3447 8.2897 4.2961 8.8208
Karpas-422 GDSC1; CTRP2 5.3534 8.5243 4.1902 9.2383
OCI-Ly10 CTRP2 5.3705 10.0297 3.4656 12.198
Jiyoye GDSC1 5.3741 7.0379 2.7723 0.6096
LP-1 GDSC1; CTRP2 5.3804 7.5915 4.6659 7.2175
SIG-M5 CTRP2 5.4489 6.9688 5.025 5.5922
H9 GDSC1 5.4774 6.9849 2.8317 0.3627
EHEB GDSC1; CTRP2 5.5141 8.8253 4.1906 8.8791
EB2 GDSC1 5.5535 7.0967 2.8206 0.3587
Kasumi-1 GDSC1; CTRP2 5.5667 9.5734 3.8675 10.1117
ARH-77 GDSC1 5.5798 7.5299 2.6726 0.8387
Sc-1 GDSC1 5.5874 6.877 2.9089 0.153
OCI-AML-5 GDSC1; CTRP2 5.6465 6.5314 5.4224 3.4999
VL51 GDSC1 5.6496 7.4602 2.7267 0.5935
ROS-50 GDSC1 5.6596 8.1027 2.4853 1.6008
SUP-HD1 GDSC1; CTRP2 5.6701 9.1201 4.1845 8.5706
HL-60 GDSC1; CTRP2 5.7703 9.3352 4.1653 8.4426
KHM-1B CTRP2 5.7723 10.4509 3.6105 10.754
ME1 CTRP2 5.8334 8.1827 4.7947 5.6751
MN-60 GDSC1 5.9664 7.9064 2.6881 0.5388
Ci-1 CTRP2 5.9907 6.6298 5.7058 1.5306
RC-K8 GDSC1 6.1 7.4603 2.8893 0.0866
Hs 611.T CTRP2 6.1164 9.449 4.4017 6.7664
RPMI-6666 GDSC1; CTRP2 6.5394 10.1042 4.4108 5.9677
MM1.S GDSC1; CTRP2 7.0538 10.3338 4.6714 4.0888
Toledo CTRP2 7.9377 21.8952 -0.3637 20.6369
CMK GDSC1; CTRP2 8.5603 13.5312 4.1318 4.2791
⏷ Show the Full List of 212 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 3.1222 5.9044 2.8925 20.2673
TE8 CTRP2 4.579 6.9625 4.1262 13.2021
OE21 GDSC1; CTRP2 2.5306 5.2233 2.3986 23.8603
TE-4 GDSC1; CTRP2 2.5929 7.014 1.9745 28.9934
T.T GDSC1 2.7768 4.8049 2.0884 11.8971
TE-6 GDSC1; CTRP2 3.1753 5.2609 3.0871 22.43
TE-15 GDSC1 3.4359 5.153 2.4996 6.0843
KYSE-270 GDSC1 3.5455 5.6773 2.325 7.0871
KYSE-180 GDSC1; CTRP2 3.9509 6.8055 3.5145 15.5221
TE-8 GDSC1 3.9762 6.3275 2.3233 5.7942
KYSE-140 GDSC1; CTRP2 4.1295 8.9329 2.8049 17.7916
TE-10 GDSC1; CTRP2 4.2776 8.3495 3.2185 15.7863
KYSE-410 GDSC1; CTRP2 4.6736 7.3112 4.0809 11.3482
TE-5 GDSC1; CTRP2 4.7313 7.5163 4.0514 11.3127
KYSE-510 GDSC1; CTRP2 4.8164 6.4673 4.5689 9.0731
TE-14 CTRP2 4.8314 7.207 4.2891 10.1115
KYSE-30 CTRP2 5.2091 6.2208 5.0792 6.0281
TE-9 GDSC1; CTRP2 5.2308 7.9401 4.3554 8.8435
TE-11 GDSC1; CTRP2 5.2914 7.2611 4.7334 7.16
KYSE-150 GDSC1; CTRP2 5.6069 6.194 5.5191 3.2312
COLO 680N GDSC1; CTRP2 5.7363 10.3529 3.6283 10.7539
EC-GI-10 GDSC1; CTRP2 5.9117 9.1642 4.3726 7.2873
OE33 GDSC1; CTRP2 5.9853 8.7369 4.6485 5.9824
OE19 GDSC1; CTRP2 6.3052 8.613 4.9704 4.0353
KYSE-520 GDSC1; CTRP2 6.788 10.2087 4.5447 5.0049
KYSE-70 GDSC1; CTRP2 7.7737 13.7817 3.5049 7.7226
KYSE-450 GDSC1; CTRP2 8.3174 9.564 5.646 0.0682
TE-1 GDSC1; CTRP2 9.2212 16.8661 2.9964 7.6969
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 6.2533 8.4025 5.0346 3.8583
MIA PaCa-2 GDSC1; CTRP2 3.1752 6.2505 2.8545 20.2429
PL4 GDSC1 3.3374 6.1479 1.9219 10.9555
MZ-PC-1 GDSC1 3.3654 5.8224 2.1077 9.4092
SNU-213 CTRP2 3.6202 9.8994 1.8524 22.7041
KP-1N GDSC1 3.6836 6.4433 2.0514 8.7643
Panc 08.13 GDSC1; CTRP2 3.9293 7.185 3.3486 16.2121
BxPC-3 GDSC1; CTRP2 4.1018 6.7568 3.6946 14.4116
SNU-410 CTRP2 4.2428 8.5343 3.1001 16.3428
Panc 02.03 GDSC1 4.3971 6.7012 2.4221 4.0153
SU.86.86 GDSC1; CTRP2 4.4421 7.8721 3.5986 16.004
CFPAC-1 GDSC1; CTRP2 4.8508 8.2722 3.8276 11.909
KP-4 GDSC1; CTRP2 4.9893 6.9603 4.5582 8.636
Panc 03.27 GDSC1; CTRP2 5.3707 7.8806 4.5183 7.8454
QGP-1 GDSC1; CTRP2 5.4346 7.6635 4.6837 7.0166
PaTu 8988s CTRP2 5.4921 6.5784 5.2432 4.612
KP-3 GDSC1; CTRP2 5.5456 9.2782 3.9951 9.6253
SW1990 GDSC1; CTRP2 5.6054 9.9195 3.7299 10.6027
PSN1 GDSC1; CTRP2 5.6145 7.7654 4.8038 6.1082
Capan-2 GDSC1; CTRP2 5.6712 7.6532 4.9111 5.5365
DAN-G GDSC1; CTRP2 5.7895 9.2129 4.243 8.0777
AsPC-1 GDSC1; CTRP2 5.8798 10.3396 3.7581 9.9238
Capan-1 GDSC1; CTRP2 5.9575 7.3091 5.3383 3.1402
Panc 04.03 GDSC1; CTRP2 6.0002 8.7819 4.6386 5.9948
Hs 766T GDSC1; CTRP2 6.0192 11.3049 3.3931 11.1615
KP-2 GDSC1; CTRP2 6.027 6.7019 5.701 1.4772
HuP-T4 GDSC1; CTRP2 6.0554 11.589 3.2812 11.5502
Panc 10.05 GDSC1; CTRP2 6.2781 10.7176 3.8996 8.5673
PaTu 8902 GDSC1; CTRP2 6.375 9.0718 4.7966 4.6405
L3.3 CTRP2 6.4336 7.7704 5.4803 1.7169
PaTu 8988t GDSC1; CTRP2 6.4757 7.7435 5.5218 1.4904
HuP-T3 GDSC1; CTRP2 6.6866 8.5601 5.2731 2.1918
SUIT-2 GDSC1; CTRP2 6.8591 9.6095 4.8867 3.5004
PK-45H CTRP2 7.2762 14.798 2.647 11.8746
Panc 05.04 CTRP2 7.8609 9.3971 5.5343 0.3342
HPAF-II GDSC1; CTRP2 7.8797 13.7082 3.6131 7.1423
YAPC GDSC1; CTRP2 8.1094 11.9936 4.5636 3.1879
PK-59 CTRP2 9.0734 18.4443 2.151 10.9491
TCC-Pan2 CTRP2 9.9392 19.7317 2.1106 9.9314
HPAC GDSC1; CTRP2 11.7735 25.1674 0.7314 12.0634
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.7383 9.2729 4.1685 8.4954
WM278 GDSC1 2.5805 5.5248 1.5547 16.8027
CHL-1 GDSC1 3.0417 5.5592 1.962 11.7681
CP50-MEL-B GDSC1 3.1494 10.8834 -0.6035 27.0686
451Lu GDSC1 3.164 5.4633 2.117 10.0835
COLO 679 GDSC1 3.2058 5.8781 1.9458 11.2575
GAK GDSC1 3.2593 4.722 2.569 6.1683
G-mel GDSC1 3.2966 5.6793 2.1221 9.5463
RPMI-7951 GDSC1; CTRP2 3.3565 5.5363 3.2325 18.3332
HMV-II GDSC1 3.4023 5.8442 2.1271 9.1264
IST-MEL1 GDSC1 3.5726 6.943 1.7159 11.6992
DJM-1 GDSC1 3.6751 5.8968 2.3157 6.742
MZ-MEL-7 GDSC1 3.9003 6.014 2.4222 5.2535
Hs 938.T GDSC1 3.9581 7.5793 1.6973 10.5762
SH-4 GDSC1 4.0208 7.0343 2.011 8.0356
A-431 GDSC1 4.0786 5.9719 2.562 3.7427
MZ-MEL-2 GDSC1 4.1065 6.449 2.354 5.2126
VMRC-MELG GDSC1 4.2071 6.5273 2.3833 4.741
WM1552C GDSC1 4.2518 6.6509 2.354 4.8462
LB2518-MEL GDSC1 4.3065 7.1861 2.1359 6.3141
A-388 GDSC1 4.3512 10.0752 0.76 15.7677
M14 GDSC1 4.3723 6.5628 2.4707 3.7263
COLO 741 CTRP2 4.4153 10.7661 2.2186 19.3418
Mel Ho GDSC1; CTRP2 4.4682 7.653 3.7213 13.3048
COLO 792 GDSC1; CTRP2 4.5409 6.3848 4.2994 10.8785
CP66-MEL GDSC1 4.7243 9.2537 1.4278 10.2907
Hs 944.T CTRP2 4.7802 8.8663 3.4787 13.4934
MeWo GDSC1; CTRP2 4.8827 7.9396 4.0136 11.079
IGR-1 GDSC1; CTRP2 4.9273 10.0555 3.0458 14.8994
UACC-257 GDSC1; CTRP2 4.9439 7.7948 4.1412 10.4124
LB373-MEL-D GDSC1 4.9492 6.181 2.9182 0.3743
LOX-IMVI GDSC1; CTRP2 5.0234 8.7947 3.7473 11.8219
MMAc-SF GDSC1 5.1715 6.9018 2.7394 0.8978
RVH-421 GDSC1; CTRP2 5.2806 7.4166 4.6507 7.5207
WM115 GDSC1; CTRP2 5.3723 5.9215 5.3405 4.5869
WM35 GDSC1 5.4388 10.4948 1.3088 9.2959
HT-144 GDSC1; CTRP2 5.4679 10.186 3.4755 11.9473
IGR-37 GDSC1; CTRP2 5.5176 7.0379 5.0612 5.276
Hs 294T CTRP2 5.5605 8.284 4.4995 7.4921
WM266-4 CTRP2 5.587 6.2483 5.4777 3.4441
Malme-3M CTRP2 5.6439 7.4857 4.9678 5.3627
CJM [Human melanoma] CTRP2 5.7179 6.3411 5.5788 2.6947
SK-MEL-24 GDSC1; CTRP2 5.7224 7.6634 4.953 5.2493
WT2-iPS GDSC1; CTRP2 5.8072 8.4494 4.6389 6.3819
WM88 CTRP2 5.8086 6.9528 5.3813 3.2782
A2058 GDSC1; CTRP2 5.8241 8.0635 4.8458 5.4802
SK-MEL-3 GDSC1; CTRP2 5.9547 9.5267 4.2279 7.8091
A101D GDSC1; CTRP2 6.0127 11.1632 3.4585 10.9046
COLO 800 GDSC1; CTRP2 6.1849 10.35 4.0075 8.29
SK-MEL-2 GDSC1; CTRP2 6.2465 7.9904 5.2342 3.0347
SK-MEL-1 GDSC1; CTRP2 6.2567 7.669 5.4016 2.3189
A-375 GDSC1; CTRP2 6.3076 8.6189 4.9694 4.0357
IPC-298 GDSC1; CTRP2 6.3323 8.315 5.1392 3.284
IGR-39 CTRP2 6.3505 9.6898 4.47 6.0496
UACC-62 GDSC1; CTRP2 6.3786 7.7758 5.4389 1.9679
Hs 934.T CTRP2 6.5191 9.8027 4.5447 5.4446
WM983B CTRP2 6.5342 9.8658 4.525 5.5012
Mel JuSo GDSC1; CTRP2 6.6002 9.0674 4.9674 3.5606
SK-MEL-5 GDSC1; CTRP2 6.6102 8.4004 5.298 2.1987
G-361 GDSC1; CTRP2 6.6634 11.1476 3.9886 7.5116
Hs 688(A).T CTRP2 6.7614 8.3377 5.4259 1.4979
Hs 895.T CTRP2 6.8103 10.0211 4.6526 4.527
Hs 839.T CTRP2 6.8113 10.911 4.2169 6.3194
COLO 829 GDSC1; CTRP2 6.8703 9.4624 4.965 3.1687
HMCB CTRP2 6.8967 9.5962 4.9188 3.3172
Hs 936.T CTRP2 7.1269 10.7684 4.5123 4.6253
Hs 940.T GDSC1; CTRP2 7.1558 10.9626 4.4386 4.881
SK-MEL-28 GDSC1; CTRP2 7.1994 8.3331 5.66 0.3482
SK-MEL-30 GDSC1; CTRP2 7.2584 12.352 3.8362 7.1705
WM793 GDSC1; CTRP2 7.32 11.983 4.0593 6.1736
WM1799 CTRP2 7.3548 11.8164 4.1641 5.6996
MDA-MB-435S CTRP2 7.515 14.7223 2.8617 10.6499
SK-MEL-31 GDSC1; CTRP2 7.7746 15.7883 2.5283 11.5107
Hs 852.T CTRP2 7.9821 13.1939 3.9268 5.7697
K029AX CTRP2 8.1286 9.9233 5.447 0.4084
EquiPSC Line K2 GDSC1 5.2041 10.964 0.9328 12.2705
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYAE-1 GDSC1 2.4551 5.9051 1.2521 19.5527
KYSE-50 GDSC1 2.8101 4.5131 2.2601 10.4322
TE-12 GDSC1 3.372 5.8526 2.098 9.4614
SK-GT-4 GDSC1 3.3746 5.409 2.3219 7.696
KYSE-220 GDSC1 3.3855 7.1133 1.479 14.1238
FLO-1 GDSC1 4.1497 13.2235 -0.9571 25.1114
HCE-4 GDSC1 4.458 6.6908 2.4637 3.5917
ESO-51 GDSC1 4.4962 12.6413 -0.399 21.6135
OACP4 C GDSC1 4.8545 9.6314 1.3349 10.5758
ESO-26 GDSC1 5.9917 7.5393 2.8258 0.1966
OACM5.1 C GDSC1 6.3826 8.3635 2.682 0.3717
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 4.3621 7.1784 3.8101 13.2426
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-14 GDSC1 2.587 7.2295 0.7263 22.4631
SJNB-5 GDSC1 2.8408 7.1286 1.0042 19.5876
GI-ME-N GDSC1 2.9538 7.2676 1.0345 18.9215
NB69 GDSC1 3.1183 5.6525 1.9829 11.305
GOTO GDSC1 3.2427 5.068 2.382 7.7043
SK-N-BE(2) CTRP2 3.3433 10.8368 1.1437 25.8766
SK-N-MC-IXC GDSC1 3.3756 4.3599 2.847 3.5557
NH-12 GDSC1 3.4052 4.8412 2.6305 5.1593
SJNB-7 GDSC1 3.4482 4.7465 2.7119 4.373
SJNB-13 GDSC1 3.4505 5.0408 2.5672 5.5024
LA-N-6 GDSC1 3.6675 5.3338 2.5875 4.6545
SJNB-10 GDSC1 3.6997 5.8114 2.3763 6.1945
TGW GDSC1 3.801 6.182 2.2689 6.7177
CHP-126 GDSC1; CTRP2 3.8023 6.023 3.6034 15.6323
SiMa GDSC1; CTRP2 3.8786 5.3511 3.8277 14.6017
SJNB-17 GDSC1 3.9503 6.0575 2.4358 5.013
Kelly GDSC1; CTRP2 4.0324 6.435 3.7308 14.4779
SK-N-AS GDSC1; CTRP2 4.179 8.1773 3.1947 16.1355
CHP-212 GDSC1; CTRP2 4.2757 7.1251 3.7402 13.7497
SK-N-SH GDSC1; CTRP2 4.6236 7.9 3.7711 12.7046
MHH-NB-11 CTRP2 4.6411 7.4093 4.0051 11.732
SJNB-12 GDSC1 4.7398 6.7861 2.58 2.2969
NB1 GDSC1; CTRP2 4.7614 6.629 4.4502 9.6782
SK-N-BE(2)-M17 GDSC1 5.0834 6.9848 2.6674 1.3277
IMR-32 CTRP2 5.2804 10.9159 2.946 14.5115
KP-N-YN GDSC1; CTRP2 5.3411 17.6609 -0.3599 25.5042
SK-N-FI GDSC1; CTRP2 5.4033 7.3809 4.788 6.6645
SK-N-DZ GDSC1; CTRP2 5.4954 6.0267 5.4501 3.8155
SJNB-6 GDSC1 5.679 7.1734 2.84 0.2616
NH-6 CTRP2 5.6797 7.3921 5.0468 4.9546
NB(TU)1 GDSC1 5.7904 7.4433 2.7865 0.3468
IMR-5 GDSC1 5.8907 7.407 2.8353 0.2061
KP-N-SI9s CTRP2 6.7451 10.0656 4.5837 4.9121
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 3.5681 6.3248 3.2604 17.5847
SNU-1079 CTRP2 3.6721 5.6846 3.5441 16.246
HuH-28 CTRP2 4.4433 7.2372 3.8715 12.7835
HuCC-T1 GDSC1; CTRP2 4.9523 7.1477 4.4396 9.2002
SNU-308 CTRP2 5.0335 6.4362 4.8139 7.5286
SNU-1196 CTRP2 5.9337 7.8793 5.0331 4.4694
SNU-869 CTRP2 6.1934 7.3903 5.4912 2.0533
SNU-245 CTRP2 6.7213 10.0646 4.5667 5.0201
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 85 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUB-M GDSC1 2.8358 4.9352 2.0814 11.6943
MDA-MB-157 GDSC1; CTRP2 2.8568 7.638 2.0301 24.1868
HCC2157 GDSC1 3.1105 5.8938 1.8558 12.3184
AU565 GDSC1; CTRP2 3.1609 5.5015 3.0275 19.6685
MCF-7 GDSC1; CTRP2 3.2306 7.153 2.6128 20.9681
MDA-MB-175-VII GDSC1 3.3464 4.6019 2.7022 4.7995
COLO 824 GDSC1 3.4339 8.5952 0.778 18.7466
HCC1187 GDSC1 3.6586 5.0226 2.7332 3.5562
HCC1569 GDSC1 3.7214 6.5921 2.0067 8.9869
EFM-192A GDSC1 3.7545 7.3142 1.6738 11.4026
EFM-19 GDSC1 3.7651 6.5208 2.0751 8.3214
CAL-120 GDSC1; CTRP2 3.8531 6.3251 3.5708 15.5977
HCC1954 GDSC1; CTRP2 4.0334 6.9955 3.5326 15.2192
Evsa-T GDSC1 4.066 5.785 2.6415 3.1946
MRK-nu-1 GDSC1 4.1112 9.2594 0.9825 15.1018
CAMA-1 GDSC1; CTRP2 4.1364 6.2048 3.9163 13.4873
CAL-85-1 GDSC1; CTRP2 4.1862 7.2469 3.5967 14.5488
MDA-MB-436 GDSC1 4.2159 6.6366 2.3373 5.0574
HCC1428 GDSC1; CTRP2 4.5551 8.9876 3.2018 15.1554
MDA-MB-453 GDSC1; CTRP2 4.591 7.041 4.1072 11.4679
BT-20 GDSC1; CTRP2 4.6261 6.9486 4.1816 11.0838
MFM-223 GDSC1 4.6304 9.428 1.2787 11.5658
UACC-893 GDSC1 4.6307 10.1203 0.9421 13.7828
SK-BR-3 CTRP2 4.6587 8.3455 3.6033 13.2879
MDA-MB-361 GDSC1; CTRP2 4.6593 7.0026 4.1949 10.9418
CAL-51 GDSC1; CTRP2 4.6644 6.6028 4.356 10.3101
MDA-MB-231 GDSC1; CTRP2 4.7636 9.6652 3.0806 15.1407
ZR-75-30 GDSC1; CTRP2 4.7843 7.1527 4.2634 10.3377
HCC1395 GDSC1; CTRP2 4.9725 8.779 3.7061 12.1104
HMC-1-8 CTRP2 5.1407 5.8929 5.0951 6.1776
HCC2218 GDSC1; CTRP2 5.1731 7.9478 4.2958 9.2247
DU4475 GDSC1; CTRP2 5.2102 5.9541 5.157 5.7419
CAL-148 CTRP2 5.2333 6.7464 4.9028 6.6355
BT-483 GDSC1 5.2855 7.3343 2.6205 1.3388
HCC70 GDSC1 5.347 7.1593 2.7156 0.8491
HCC1500 GDSC1; CTRP2 5.3544 7.6108 4.6316 7.4197
HCC1937 GDSC1; CTRP2 5.3589 9.7578 3.5895 11.7122
MDA-MB-468 GDSC1; CTRP2 5.4044 8.214 4.389 8.3005
HDQ-P1 GDSC1; CTRP2 5.525 7.7464 4.7294 6.6187
HCC202 GDSC1; CTRP2 5.559 8.9791 4.1552 8.9297
BT-549 GDSC1; CTRP2 5.6544 9.9501 3.7577 10.3847
JIMT-1 GDSC1; CTRP2 5.8955 7.9592 4.9603 4.8526
HCC1419 GDSC1; CTRP2 5.9355 10.0202 3.965 8.9488
Hs 578T GDSC1; CTRP2 5.9418 9.5442 4.2083 7.917
HCC38 GDSC1; CTRP2 5.9788 9.7773 4.123 8.2019
T-47D GDSC1; CTRP2 6.0999 15.2494 1.4881 18.3101
KPL-1 CTRP2 6.1009 6.9036 5.6609 1.7399
BT-474 GDSC1; CTRP2 6.365 8.835 4.9064 4.199
ZR-75-1 CTRP2 7.6668 8.9951 5.6051 0.2661
HCC1806 GDSC1; CTRP2 7.8428 12.8252 4.0102 5.6296
HCC1143 GDSC1; CTRP2 7.8904 15.3405 2.8305 10.1792
BT 416 CTRP2 4.0338 5.6047 3.9526 13.6731
BT 231 CTRP2 5.0923 7.8471 4.2641 9.549
BT 145 CTRP2 5.1914 8.6397 3.9818 10.4686
BT 248 CTRP2 5.3338 6.2548 5.2028 5.2045
BT 216 CTRP2 5.3408 6.3633 5.1708 5.3051
BT 428 CTRP2 5.3831 6.5228 5.1528 5.2574
BT 330 CTRP2 5.5226 6.0501 5.4734 3.6487
BT147 CTRP2 5.5487 7.3572 4.9399 5.6971
BT 245 CTRP2 5.5664 7.1664 5.0482 5.2115
BT 131 CTRP2 5.6282 6.1611 5.5537 3.0398
BT 271 CTRP2 5.6713 6.4294 5.4927 3.1567
BT 228 CTRP2 5.7565 7.4275 5.1003 4.5613
BT 422 CTRP2 5.9185 6.4945 5.7074 1.6799
BT 172 CTRP2 5.9297 7.3443 5.2966 3.3719
BT 286 CTRP2 5.9933 6.8328 5.6068 1.9405
BT 504 CTRP2 6.0587 6.8527 5.6521 1.6214
BT 359 CTRP2 6.0839 8.7557 4.7216 5.4845
BT 179 CTRP2 6.1502 7.0625 5.6206 1.5875
BT 232 CTRP2 6.1701 7.9075 5.2154 3.2493
BT 333 CTRP2 6.2405 7.1791 5.631 1.3937
BT 239 CTRP2 6.3308 8.8594 4.8679 4.4193
BT 482 CTRP2 6.3711 7.8199 5.412 2.0901
BT 187 CTRP2 6.4325 8.0195 5.3586 2.2141
BT 440 CTRP2 6.5999 8.4238 5.2798 2.2867
BT 328 CTRP2 6.6062 8.5615 5.2177 2.5286
BT 340 CTRP2 6.6136 8.0458 5.469 1.5153
BT 112 CTRP2 6.6478 8.4642 5.2929 2.1662
BT 444 CTRP2 6.8152 8.6373 5.3202 1.8383
BT 159 CTRP2 6.8205 8.7164 5.2866 1.9619
BT 224 CTRP2 6.9262 9.3249 5.068 2.6816
BT 498 CTRP2 7.1247 8.3747 5.609 0.5289
BT164 CTRP2 7.1322 9.7666 4.9929 2.7082
BT 320 CTRP2 7.208 8.3941 5.6398 0.3941
BT 139 CTRP2 7.6866 8.8334 5.6715 0.1464
⏷ Show the Full List of 85 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 4.8872 7.4153 4.2555 10.0986
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MOG-G-UVW GDSC1 2.7854 7.05 0.9938 19.8879
D-336MG GDSC1 3.3178 7.0073 1.4758 14.3958
D-566MG GDSC1 3.3483 5.3844 2.3125 7.8638
D-423MG GDSC1 3.513 6.0311 2.1231 8.7735
H4 GDSC1 3.5767 7.1825 1.5996 12.555
KNS-60 CTRP2 3.618 8.806 2.3433 24.0296
KINGS-1 GDSC1 3.6247 5.7129 2.3684 6.4903
KS-1 [Human Krukenberg tumour] GDSC1 3.6285 6.3513 2.0545 8.9199
AM-38 GDSC1 3.6332 7.7115 1.3809 13.9556
SK-MG-1 GDSC1 3.7374 6.7155 1.9577 9.3113
D283 Med GDSC1; CTRP2 3.794 6.7049 3.381 16.4743
LNZTA3WT4 GDSC1 3.8341 5.606 2.5734 4.2855
Onda 10 GDSC1 3.952 6.4588 2.2425 6.4766
GI-1 GDSC1 4.0057 6.9053 2.0632 7.6849
LN-405 GDSC1 4.0538 6.9371 2.082 7.4042
MOG-G-CCM GDSC1 4.0609 7.83 1.6502 10.6069
D-542MG GDSC1 4.1385 8.9901 1.1363 13.9925
D-263MG GDSC1 4.1698 7.911 1.6899 9.9888
D-502MG GDSC1 4.194 6.6534 2.3149 5.2789
PFSK-1 GDSC1 4.2392 6.6083 2.3659 4.7897
SF268 GDSC1; CTRP2 4.2711 8.1746 3.29 15.521
Daoy GDSC1; CTRP2 4.5566 7.477 3.8886 12.4136
M059J GDSC1 4.601 11.493 0.2471 18.0086
LN-18 GDSC1; CTRP2 4.6366 5.3354 4.629 9.4044
D-247MG GDSC1 4.6711 7.0601 2.4215 3.4491
D-392MG GDSC1 4.8454 6.8243 2.6183 1.9033
SF539 GDSC1; CTRP2 5.0267 10.3713 2.9836 14.9234
SNU-466 CTRP2 5.0787 6.1234 4.9679 6.8239
KNS-81 CTRP2 5.1625 17.3744 -0.3713 28.5941
SNU-626 CTRP2 5.2374 7.4997 4.5693 7.9569
SW1783 GDSC1; CTRP2 5.2504 10.0039 3.3695 12.856
GB-1 GDSC1; CTRP2 5.28 9.7604 3.5164 12.1873
CAS-1 GDSC1; CTRP2 5.3408 6.2075 5.2266 5.8867
Hs 683 GDSC1; CTRP2 5.3545 7.3663 4.747 6.9493
U-251MG GDSC1; CTRP2 5.3705 6.6693 5.0782 5.5823
T98G GDSC1; CTRP2 5.4218 8.6563 4.1891 9.089
42-MG-BA GDSC1; CTRP2 5.4246 11.3905 2.8387 14.6307
SF126 GDSC1; CTRP2 5.4804 9.162 3.9938 9.7715
ONS-76 GDSC1; CTRP2 5.5408 7.3672 4.9275 5.7664
SNU-738 CTRP2 5.5612 7.7129 4.7798 6.3281
KNS-81-FD GDSC1 5.5668 7.1988 2.7892 0.4413
SF295 GDSC1; CTRP2 5.6031 9.5746 3.8993 9.9023
LN-229 GDSC1; CTRP2 5.8938 8.5048 4.6866 6.0048
KNS-42 GDSC1; CTRP2 6.0023 7.9133 5.0747 4.158
SNB-75 GDSC1; CTRP2 6.0392 13.6602 2.2321 15.7308
A-172 GDSC1; CTRP2 6.0413 7.7332 5.1974 3.5659
YKG-1 GDSC1; CTRP2 6.0596 6.8523 5.653 1.616
U-118MG GDSC1; CTRP2 6.0918 8.2966 4.9575 4.4778
KG-1-C CTRP2 6.2767 10.3375 4.0882 7.7817
SNU-489 CTRP2 6.4819 8.7771 5.0233 3.518
NMC-G1 GDSC1; CTRP2 6.561 8.6763 5.1302 2.953
M059K CTRP2 6.6025 10.4019 4.3115 6.2741
Onda 11 GDSC1 6.6988 8.8625 2.6235 0.3926
TM-31 CTRP2 6.7619 8.9246 5.1495 2.5814
CCF-STTG1 CTRP2 6.7871 9.354 4.9602 3.3077
SNU-201 CTRP2 6.7895 9.6204 4.8329 3.8213
GOS-3 CTRP2 6.8203 8.8055 5.2445 2.1264
DK-MG GDSC1; CTRP2 7.1702 11.8044 4.0402 6.4773
GaMG GDSC1; CTRP2 7.2216 12.0548 3.9548 6.7456
SW1088 GDSC1; CTRP2 7.2441 13.4933 3.2663 9.4925
U-87MG ATCC GDSC1; CTRP2 7.2948 11.9339 4.0654 6.1862
Becker GDSC1; CTRP2 7.46 13.7096 3.3179 8.9413
8-MG-BA GDSC1; CTRP2 7.7248 11.7314 4.4496 4.0681
SNU-1105 CTRP2 7.7667 11.6208 4.5274 3.7174
GMS-10 CTRP2 7.9148 11.9226 4.4792 3.7232
YH-13 GDSC1; CTRP2 8.4636 14.7727 3.4942 6.8063
KALS-1 GDSC1; CTRP2 8.4814 16.5607 2.6525 9.9713
DBTRG-05MG GDSC1; CTRP2 8.6603 24.4775 -1.0933 21.3408
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1 1.8523 5.7496 0.7389 25.8521
ETK-1 GDSC1 3.0536 5.0165 2.2418 9.5411
TGBC1TKB GDSC1 4.2729 8.7031 1.3768 11.925
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2 2.8299 4.3482 2.8168 21.4591
HEC-59 CTRP2 3.8759 6.346 3.5891 15.4629
KLE GDSC1; CTRP2 3.9207 7.159 3.3494 16.233
MFE-296 GDSC1; CTRP2 4.5039 9.2131 3.0456 15.9049
RL95-2 CTRP2 4.7015 7.995 3.8067 12.3644
HEC-1-A CTRP2 4.8617 7.8578 4.0301 11.0649
HEC-265 CTRP2 4.9462 6.3684 4.7441 8.0419
HEC-50B CTRP2 5.1412 7.2313 4.596 8.0899
HEC-108 CTRP2 5.2833 6.8518 4.9093 6.4778
JHUEM-7 CTRP2 5.3235 11.3164 2.7859 15.0583
HEC-151 CTRP2 5.3405 6.7554 5.0102 5.9293
HEC-6 CTRP2 5.36 7.296 4.7853 6.7805
JHUEM-1 CTRP2 5.387 5.854 5.3685 4.4426
JHUEM-3 CTRP2 5.7741 7.9864 4.8399 5.6102
HEC-251 CTRP2 5.8215 12.2282 2.7648 14.0999
MFE-319 GDSC1; CTRP2 5.8228 6.5394 5.5945 2.3671
ESS-1 GDSC1; CTRP2 6.0703 8.6397 4.7682 5.3145
MFE-280 GDSC1 6.1034 8.2916 2.6016 0.7397
EFE-184 CTRP2 7.0275 10.272 4.6832 4.0792
AN3-CA GDSC1; CTRP2 7.3722 13.2211 3.4935 8.377
EN GDSC1; CTRP2 7.3837 10.6933 4.7188 3.4548
HEC-1-B CTRP2 7.952 15.0206 3.0295 9.3188
Ishikawa (Heraklio) 02 ER- CTRP2 5.4591 5.9897 5.4197 4.0359
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW156 GDSC1 1.3635 4.364 0.8312 27.9259
LB1047-RCC GDSC1 2.2633 7.2772 0.4051 25.8178
KTCTL-13 GDSC1 2.9587 5.437 1.9482 12.2091
LB2241-RCC GDSC1 3.0288 5.8181 1.8218 12.9006
KTCTL-1M GDSC1 3.0962 6.5524 1.5149 14.9505
NCC021 GDSC1 3.3938 6.2794 1.9027 10.9006
KTCTL-26A GDSC1 3.4188 10.7669 -0.3202 24.8178
HA7-RCC GDSC1 3.4274 5.3087 2.415 6.7785
UO-31 GDSC1; CTRP2 3.464 8.3159 2.3964 21.1202
LB996-RCC GDSC1 3.5306 6.303 2.0015 9.6586
KTCTL-140 GDSC1 3.5622 6.0428 2.1562 8.3505
SN12C GDSC1 3.6427 5.209 2.6305 4.3952
RXF 393L GDSC1 3.7043 6.1501 2.2125 7.4512
SW13 GDSC1 3.7271 7.4706 1.5748 12.2271
NCC010 GDSC1 3.7617 5.9838 2.3374 6.307
KTCTL-21 GDSC1 4.0927 7.2407 1.9618 8.197
BFTC-909 GDSC1; CTRP2 4.3076 6.649 3.9553 12.8408
BB65-RCC GDSC1 4.3441 8.4292 1.5619 10.4068
KMRC-3 CTRP2 4.4432 9.6694 2.7707 17.1423
TK-10 GDSC1 4.7153 8.1672 1.9388 6.7243
TUHR4TKB CTRP2 4.7697 6.8768 4.3622 9.9926
VMRC-RCZ GDSC1; CTRP2 4.9211 8.0165 4.0161 10.9739
SNU-1272 CTRP2 4.9994 7.1807 4.4738 8.9419
KTCTL-195 GDSC1 5.091 6.9652 2.6787 1.2622
TUHR10TKB CTRP2 5.0951 8.1091 4.1435 10.0328
CAL-54 GDSC1; CTRP2 5.3435 8.2577 4.3105 8.7641
KMRC-20 GDSC1; CTRP2 5.4528 8.6359 4.2277 8.86
TUHR14TKB CTRP2 5.5306 12.5483 2.355 29.8491
KMRC-1 GDSC1; CTRP2 6.0655 8.5812 4.7936 5.217
Caki-2 CTRP2 6.1258 8.4479 4.9098 4.6146
786-O GDSC1; CTRP2 6.1543 11.4198 3.4477 10.6754
A-498 GDSC1; CTRP2 6.3766 7.7532 5.4485 1.9317
KMRC-2 CTRP2 6.5817 9.1085 4.9338 3.7279
OS-RC-2 GDSC1; CTRP2 6.7722 14.5308 2.3914 13.735
Caki-1 GDSC1; CTRP2 6.9939 9.6873 4.9405 3.0955
VMRC-RCW CTRP2 7.6096 11.368 4.5465 3.8378
769-P GDSC1; CTRP2 7.89 12.2203 4.3256 4.34
ACHN GDSC1; CTRP2 8.251 10.1895 5.3974 0.4632
RCC10RGB GDSC1; CTRP2 8.34 13.6445 3.9446 5.2421
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-81 GDSC1; CTRP2 2.7134 6.5769 2.251 23.8175
CCK-81 GDSC1 3.421 6.1213 2.0039 10.0206
HT115 GDSC1; CTRP2 3.4971 5.526 3.3869 17.3484
SK-CO-1 GDSC1; CTRP2 3.5193 5.2624 3.4561 17.0376
COLO 320HSR GDSC1 3.5316 5.5946 2.3553 6.8955
SW48 GDSC1; CTRP2 3.5705 5.2881 3.5071 16.6971
CW-2 GDSC1; CTRP2 3.7145 6.5403 3.3509 16.8181
CaR-1 GDSC1 3.81 5.8138 2.4556 5.2534
GP5d GDSC1 3.9162 6.0281 2.4264 5.1771
SNU-C1 GDSC1; CTRP2 4.0368 6.8422 3.5935 14.9789
HCC2998 GDSC1 4.0674 6.1347 2.4778 4.3912
T84 GDSC1; CTRP2 4.0862 6.077 3.8984 13.7039
SW837 GDSC1 4.1266 8.3183 1.4585 11.7915
CL-11 GDSC1; CTRP2 4.1968 9.5737 2.5751 18.5148
LoVo GDSC1; CTRP2 4.3173 7.486 3.636 14.0401
NCI-H747 GDSC1; CTRP2 4.5293 7.1451 3.9997 12.0523
DiFi GDSC1 4.5652 7.1362 2.3244 4.336
HCT 15 GDSC1; CTRP2 4.602 7.0937 4.0973 11.4759
C2BBe1 GDSC1; CTRP2 4.646 7.2002 4.0992 11.3499
RKO GDSC1; CTRP2 4.7309 8.7749 3.474 13.6317
KM12 GDSC1; CTRP2 4.7608 7.9481 3.8877 11.8902
SNU-C2B GDSC1 4.7811 8.7225 1.7194 8.1137
COLO 320 CTRP2 4.8213 14.8316 0.594 23.948
LS180 GDSC1; CTRP2 4.8496 6.6042 4.554 9.0353
DLD-1 CTRP2 4.896 6.109 4.7729 8.0834
SNU-61 GDSC1; CTRP2 4.911 7.2399 4.357 9.6348
SW1463 GDSC1; CTRP2 4.912 6.2778 4.7378 8.1647
LS513 GDSC1; CTRP2 4.9621 6.0576 4.8596 7.5695
NCI-H508 GDSC1; CTRP2 5.0002 6.7354 4.6627 8.2001
SW626 GDSC1 5.0648 7.2155 2.5643 1.9051
SW1116 GDSC1 5.302 6.6136 2.8974 0.2658
MDST8 GDSC1; CTRP2 5.3092 8.9266 3.9526 10.3207
HT-29 GDSC1; CTRP2 5.3287 6.5938 5.0664 5.7408
LS1034 GDSC1; CTRP2 5.3933 8.0029 4.4809 7.9468
OUMS-23 CTRP2 5.4201 7.6841 4.66 7.1479
HCC-56 CTRP2 5.489 5.9723 5.4563 3.8131
SNU-1033 CTRP2 5.503 9.2499 3.9707 9.8185
HCT 116 GDSC1; CTRP2 5.5245 6.0397 5.4783 3.6253
HCT 8 CTRP2 5.6105 6.2919 5.4861 3.3462
SNU-503 CTRP2 5.7103 9.2542 4.1532 8.6176
SW948 GDSC1; CTRP2 5.7928 6.5279 5.5706 2.5373
SNU-C4 CTRP2 5.9011 6.4994 5.6887 1.797
SW1417 GDSC1; CTRP2 5.9401 10.2894 3.8344 9.4855
LS411N GDSC1; CTRP2 5.9576 7.0535 5.4658 2.6051
HT-55 GDSC1; CTRP2 6.0306 6.9965 5.5568 2.0765
COLO205 GDSC1; CTRP2 6.1128 8.7426 4.7519 5.3021
NCI-H716 GDSC1; CTRP2 6.1305 12.0386 3.1187 12.0675
SNU-C2A CTRP2 6.1316 11.8047 3.2366 11.5851
GP2d CTRP2 6.2607 12.945 2.7726 13.2052
COLO201 CTRP2 6.4876 9.8631 4.4906 5.7237
RCM-1 [Human ESC] GDSC1; CTRP2 6.5483 8.6477 5.135 2.9526
SNU-C5 GDSC1; CTRP2 6.5783 10.9233 4.0344 7.4678
SNU-407 GDSC1; CTRP2 6.7137 9.9258 4.6293 4.7739
SW620 GDSC1; CTRP2 6.9235 10.7467 4.3795 5.4717
COLO 678 GDSC1; CTRP2 7.1214 11.9394 3.9391 6.9651
LS123 GDSC1; CTRP2 8.7726 14.5083 3.8122 5.2208
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 4.4656 8.8998 1.4191 11.0665
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Huh-7 GDSC1 2.5646 4.5771 1.9889 13.6171
JHH-1 GDSC1 2.7943 5.2416 1.8934 13.3179
SNU-878 CTRP2 2.8445 5.3976 2.7052 21.7957
HLE GDSC1 3.1935 6.1179 1.8155 12.309
Hep 3B2.1-7 GDSC1; CTRP2 3.3636 7.3355 2.687 20.3102
SNU-182 CTRP2 3.6057 5.9682 3.4034 16.9524
JHH-7 GDSC1 3.762 7.9269 1.3751 13.5581
Hep-G2/C3A GDSC1 3.815 6.3884 2.1777 7.3776
Li-7 CTRP2 4.0631 7.9962 3.1546 16.5978
SNU-761 CTRP2 4.3058 8.425 3.2131 18.1557
SNU-398 GDSC1; CTRP2 4.4307 8.1667 3.4558 14.4532
HuH-6 CTRP2 4.469 6.5089 4.1791 11.5362
HuH-1 GDSC1; CTRP2 4.5696 7.9028 3.715 13.0666
JHH-4 GDSC1; CTRP2 4.8893 8.2566 3.8727 11.632
SNU-886 CTRP2 5.1055 7.0986 4.6187 8.0917
JHH-5 CTRP2 5.3085 7.0214 4.8597 6.6098
SNU-449 GDSC1; CTRP2 5.5298 8.2411 4.4924 7.59
PLC/PRF/5 CTRP2 5.6674 7.1899 5.1335 4.6243
Hep-G2 CTRP2 6.2191 11.7836 3.3191 11.0807
HLF CTRP2 6.6162 9.7205 4.6584 5.5572
SNU-387 GDSC1; CTRP2 6.6344 11.9549 3.5653 9.3101
SNU-475 CTRP2 6.6539 8.2296 5.4084 1.7004
SK-HEP-1 GDSC1; CTRP2 6.7813 8.2809 5.4642 1.3298
JHH-2 GDSC1; CTRP2 7.0209 8.9283 5.3121 1.626
SNU-423 GDSC1; CTRP2 7.0944 8.9771 5.3331 1.4696
JHH-6 GDSC1; CTRP2 7.2212 7.9882 5.7965 0.0785
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 212 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC44 GDSC1; CTRP2 2.1791 6.1089 1.8083 27.0269
Sq-1 CTRP2 2.3846 6.5474 1.9025 26.0583
RERF-LC-KJ GDSC1 2.6347 4.3471 2.1646 11.9643
NCI-H1648 GDSC1 2.7441 6.2006 1.3766 17.3962
RERF-LC-Sq1 GDSC1 2.8171 6.2229 1.4319 16.688
NCI-H1734 GDSC1; CTRP2 2.8233 5.3453 2.6923 21.9079
EMC-BAC-2 GDSC1 2.8594 5.992 1.5843 15.3865
NCI-H2085 GDSC1; CTRP2 3.0609 5.8223 2.8463 20.6212
NCI-H3255 GDSC1 3.2815 5.7933 2.0524 10.1459
NCI-H1437 GDSC1 3.295 5.155 2.3829 7.5032
NCI-H2347 GDSC1 3.305 5.2684 2.3345 7.8476
PaCa-3 GDSC1 3.3593 7.2716 1.3781 14.9529
NCI-H1693 GDSC1 3.3842 6.4727 1.7982 11.7372
NCI-H211 GDSC1; CTRP2 3.3874 5.3867 3.2941 18.02
UMC-11 GDSC1 3.3997 6.0706 2.0118 10.0342
DMS 454 CTRP2 3.402 6.5666 3.0029 19.0233
NCI-H82 GDSC1 3.4077 5.0663 2.5202 6.0191
Lu-135 GDSC1 3.4151 5.403 2.358 7.2704
SBC-1 GDSC1 3.427 5.534 2.3022 7.6674
NCI-H1975 GDSC1 3.4272 6.7903 1.6747 12.5195
HCC827 GDSC1; CTRP2 3.4532 6.156 3.1853 18.2032
NCI-H1048 GDSC1 3.4582 5.3026 2.4428 6.4549
NCI-H1915 GDSC1; CTRP2 3.4652 6.8332 1.6842 8.0735
MOR/CPR CTRP2 3.4882 5.0275 3.4527 17.1493
A-427 GDSC1 3.5082 5.4062 2.4307 6.3821
NCI-H2170 GDSC1; CTRP2 3.517 6.0857 3.2748 17.6863
NCI-H3122 GDSC1 3.5486 5.2424 2.5435 5.3658
NCI-H290 GDSC1 3.5522 5.8903 2.2243 7.8521
NCI-H1876 GDSC1 3.5585 5.0633 2.6397 4.5824
IST-SL2 GDSC1 3.6016 5.8256 2.2948 7.139
NCI-H2369 GDSC1 3.6056 8.2686 1.0809 16.1435
NCI-H2810 GDSC1 3.6374 7.4719 1.5037 13.0523
LUDLU-1 CTRP2 3.647 7.1212 3.0715 18.0586
DV-90 CTRP2 3.6521 6.2134 3.3856 16.8762
COR-L23 GDSC1 3.695 6.5097 2.0273 8.9137
NCI-H2373 GDSC1 3.6985 5.6141 2.4726 5.4513
LC-1/sq GDSC1 3.6992 8.9132 0.8341 17.4397
NCI-H1781 GDSC1 3.7064 6.801 1.8916 9.9173
IST-SL1 GDSC1 3.7357 5.3283 2.6391 4.0583
NCI-H1993 GDSC1 3.745 8.2801 1.186 14.9423
NCI-H1581 GDSC1; CTRP2 3.7623 6.1865 3.5137 16.0784
SBC-3 GDSC1 3.7652 5.3768 2.6364 3.9968
NCI-H209 GDSC1; CTRP2 3.7673 6.4659 3.4326 18.9007
CPC-N GDSC1 3.7677 6.3242 2.1742 7.5502
NCI-H2731 GDSC1 3.7838 7.5644 1.5723 12.0575
NCI-H1304 GDSC1 3.8082 5.8608 2.4314 5.4448
EPLC-272H GDSC1; CTRP2 3.8173 6.4221 3.5012 15.9599
PC-14 GDSC1; CTRP2 3.8615 6.2791 3.5941 17.8924
NCI-H2804 GDSC1 3.878 8.7104 1.0759 15.2433
NCI-H1563 GDSC1; CTRP2 3.8846 7.0363 3.3579 16.3023
Lu-99A GDSC1 3.8859 8.0149 1.4273 12.7753
NCI-H2461 GDSC1 3.9094 5.8769 2.4947 4.6773
ABC-1 GDSC1 3.9219 5.9845 2.4514 4.9713
NCI-H2803 GDSC1 3.9278 6.4585 2.2254 6.6768
NCI-H1688 GDSC1 3.962 6.1091 2.419 5.1084
NCI-H2722 GDSC1 3.9832 5.7051 2.6261 3.5037
LB647-SCLC GDSC1 4.025 6.3415 2.3503 5.4568
CAL-12T GDSC1; CTRP2 4.0337 7.1935 3.4563 15.5096
NCI-H1568 GDSC1; CTRP2 4.0403 7.7538 3.2344 16.3481
NCI-H64 GDSC1 4.0436 6.0925 2.4821 4.4198
NCI-H2795 GDSC1 4.0588 6.6067 2.2457 6.1536
NCI-H524 GDSC1 4.0806 6.2783 2.4182 4.8011
EKVX GDSC1; CTRP2 4.0988 8.015 3.1834 16.3906
NCI-H69 GDSC1; CTRP2 4.1119 5.6953 4.0195 13.1923
NCI-H647 GDSC1; CTRP2 4.172 7.8899 3.313 15.6898
NCI-H661 GDSC1; CTRP2 4.1741 7.8403 3.3365 15.5927
NCI-H358 GDSC1; CTRP2 4.223 7.5227 3.5222 14.7373
NCI-H1355 GDSC1; CTRP2 4.2234 6.983 3.7403 13.8945
HCC15 GDSC1; CTRP2 4.2272 6.7183 3.8436 13.4919
Calu-3 GDSC1; CTRP2 4.2604 5.9707 4.1171 12.3843
SW1573 GDSC1 4.3184 7.1197 2.1755 5.9921
LC-2/ad GDSC1 4.321 6.3424 2.5408 3.3443
Ms-1 GDSC1 4.3392 5.98 2.7144 2.128
HCC2935 CTRP2 4.384 9.3975 2.8415 17.0085
NCI-H889 CTRP2 4.3903 6.9697 3.9231 12.7297
COR-L105 GDSC1; CTRP2 4.3944 8.4293 3.3004 15.1632
NCI-H2135 GDSC1 4.4124 7.5298 2.0427 6.7268
SW1271 GDSC1; CTRP2 4.4126 7.1593 3.8711 14.8667
NCI-H1944 GDSC1; CTRP2 4.4156 6.5369 4.1115 11.9437
NCI-H522 GDSC1; CTRP2 4.4162 6.3399 4.1789 11.6911
NCI-H2869 GDSC1 4.4252 7.2262 2.1948 5.5847
NCI-H1666 GDSC1; CTRP2 4.4313 7.0095 3.951 12.5091
NCI-H1435 GDSC1; CTRP2 4.4345 8.5494 3.2858 15.1199
NCI-H2106 CTRP2 4.444 5.3983 4.4227 10.7341
NCI-H1623 GDSC1; CTRP2 4.4466 6.9629 3.9856 12.3336
DMS 53 GDSC1; CTRP2 4.4501 5.888 4.3446 10.987
NCI-H187 GDSC1 4.466 6.6641 2.4806 3.4577
ChaGo-K-1 GDSC1; CTRP2 4.4706 7.7226 3.6935 13.4082
COR-L321 GDSC1 4.4937 6.0478 2.7672 1.5437
NCI-H1436 GDSC1 4.4953 6.0655 2.7606 1.5809
EMC-BAC-1 GDSC1 4.5174 9.7737 1.0299 13.546
NCI-H146 GDSC1 4.5249 7.6983 2.0367 6.4868
LCLC-97TM1 GDSC1; CTRP2 4.5401 6.7149 4.1809 11.326
NCI-H2087 GDSC1; CTRP2 4.5943 7.0388 4.1116 11.4416
NCI-H2595 GDSC1 4.6045 11.9256 0.0366 19.1273
NCI-H1155 GDSC1; CTRP2 4.6165 5.8455 4.5355 9.7926
NCI-H2228 GDSC1; CTRP2 4.6218 6.6628 4.2879 12.3494
NCI-H2591 GDSC1 4.6417 7.0327 2.4168 3.5385
NCI-H446 GDSC1; CTRP2 4.6466 6.2238 4.4665 9.9498
NCI-H2081 GDSC1; CTRP2 4.6642 6.3216 4.4542 9.9431
NCI-H510A GDSC1 4.6758 6.4034 2.7096 1.6159
NCI-H1792 GDSC1; CTRP2 4.6983 7.5782 3.9904 11.6402
NCI-H596 GDSC1 4.7006 6.3959 2.7251 1.4935
COR-L95 GDSC1; CTRP2 4.7146 6.9225 4.2857 10.4394
NCI-H2444 GDSC1; CTRP2 4.7199 10.6905 2.5425 19.926
NCI-H810 GDSC1; CTRP2 4.7336 6.2287 4.5596 9.3493
NCI-H1650 GDSC1; CTRP2 4.7423 9.459 3.1593 14.8745
NCI-H520 GDSC1; CTRP2 4.7714 6.5079 4.5058 9.4394
NCI-H226 GDSC1; CTRP2 4.7874 7.1795 4.2553 11.9703
NCI-H1373 CTRP2 4.7969 7.3554 4.1893 10.596
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 4.809 7.8 4.0035 11.3044
Lu-99 CTRP2 4.8113 5.9018 4.7347 8.4801
NCI-H2818 GDSC1 4.8199 6.7907 2.6195 1.9333
NCI-H2171 CTRP2 4.8379 6.9085 4.4213 9.5779
NCI-H1694 GDSC1; CTRP2 4.8595 6.6854 4.5334 9.086
NCI-H835 GDSC1 4.8799 7.5794 2.3086 3.8013
HCC1588 CTRP2 4.9027 6.5788 4.6205 8.6328
COLO 668 GDSC1; CTRP2 4.9063 6.4947 4.6557 8.4891
NCI-H1341 GDSC1; CTRP2 4.9122 7.0854 4.4249 9.3639
NCI-H23 GDSC1; CTRP2 4.9213 7.0069 4.4677 9.172
HOP-92 GDSC1; CTRP2 4.9396 9.0717 3.534 12.8899
NCI-H2030 GDSC1; CTRP2 4.9538 9.8342 3.1784 14.3031
NCI-H1573 GDSC1; CTRP2 4.9945 6.1945 4.8544 7.4911
NCI-H345 GDSC1 5.008 6.1464 2.9529 0.2454
SBC-5 GDSC1; CTRP2 5.0368 5.8662 4.9878 6.8811
SHP-77 GDSC1; CTRP2 5.0477 6.497 4.8065 7.5166
HCC366 GDSC1; CTRP2 5.088 7.8271 4.2692 9.5392
HOP-62 GDSC1; CTRP2 5.1179 10.2245 3.1397 14.0878
NCI-H720 GDSC1 5.134 6.4563 2.8901 0.3617
HCC4006 CTRP2 5.1396 16.386 0.1015 24.6821
HCC1438 CTRP2 5.1479 7.3576 4.5455 8.2753
LOU-NH91 GDSC1; CTRP2 5.1519 7.1351 4.6499 7.8477
SK-MES-1 GDSC1; CTRP2 5.182 7.3407 4.5875 8.0207
Lu-165 GDSC1 5.2078 6.6819 2.837 0.4898
NCI-H2009 GDSC1; CTRP2 5.2124 10.9718 2.8571 15.0169
NCI-H727 GDSC1; CTRP2 5.2371 8.5869 4.0505 10.0803
NCI-H513 GDSC1 5.2521 7.3893 2.5831 1.5655
NCI-H1838 GDSC1; CTRP2 5.2538 8.442 4.1365 9.6875
NCI-H2405 GDSC1; CTRP2 5.2578 8.4678 4.1277 9.7147
NCI-H1869 GDSC1; CTRP2 5.275 8.8022 3.9815 10.2785
NCI-H526 GDSC1; CTRP2 5.2884 6.3382 5.1239 5.6316
Lu-65 GDSC1; CTRP2 5.3162 6.7793 4.9747 6.1331
NCI-H650 GDSC1; CTRP2 5.3169 8.2812 4.274 8.9758
DMS 273 GDSC1; CTRP2 5.3183 8.6318 4.105 9.6699
DMS 114 GDSC1; CTRP2 5.3649 7.8591 4.5232 7.8388
NCI-H847 GDSC1 5.3832 6.9139 2.8212 0.4405
RERF-LC-A1 CTRP2 5.4069 9.1537 3.9311 10.1928
EBC-1 GDSC1; CTRP2 5.4235 8.0545 4.4844 7.8631
NCI-H1299 GDSC1; CTRP2 5.4255 8.5191 4.2598 8.7877
NCI-H1651 GDSC1 5.4259 7.5645 2.5928 1.3256
NCI-H1836 GDSC1 5.4298 6.8486 2.8621 0.3028
NCI-H2029 GDSC1; CTRP2 5.4329 6.3045 5.2915 4.5867
NCI-H2227 GDSC1 5.4373 7.1071 2.7721 0.5697
NCI-H2066 GDSC1 5.4413 7.1457 2.7594 0.6112
NCI-H1963 GDSC1 5.4428 7.4348 2.6509 1.0427
NCI-H1703 GDSC1; CTRP2 5.4482 9.8 3.6492 11.2719
HCC1833 CTRP2 5.4838 7.7665 4.6808 6.914
NCI-H322M GDSC1 5.4861 7.4279 2.672 0.9152
NCI-H322 CTRP2 5.5133 7.4783 4.848 6.1575
LK-2 GDSC1 5.529 7.0658 2.8224 0.3647
NCI-H1092 GDSC1 5.5291 7.5983 2.625 1.0786
NCI-H2110 GDSC1; CTRP2 5.5719 9.1752 4.0697 9.2581
NCI-H1339 CTRP2 5.5723 8.5265 4.3908 7.9186
HCC1195 CTRP2 5.5861 8.0575 4.6343 6.8752
NCI-H292 GDSC1; CTRP2 5.6035 10.0301 3.6732 10.8425
COR-L88 GDSC1; CTRP2 5.6484 6.3197 5.5151 3.1302
HCC95 CTRP2 5.6493 7.9185 4.7607 6.2102
COR-L279 GDSC1 5.6702 7.1128 2.8577 0.2264
NCI-H2291 GDSC1; CTRP2 5.6825 11.3898 3.0644 13.1809
HCC2279 CTRP2 5.6891 8.4633 4.5274 7.097
T3M-10 CTRP2 5.6951 9.304 4.1151 8.8085
NCI-H1770 GDSC1 5.7208 6.942 2.933 0.0922
VMRC-LCD GDSC1; CTRP2 5.7609 8.5704 4.538 6.9014
DMS 79 GDSC1 5.761 7.7124 2.6783 0.6902
LK2 CTRP2 5.7899 6.1446 5.734 1.8978
IA-LM GDSC1; CTRP2 5.7908 6.6114 5.5293 2.7099
NCI-H2141 GDSC1 5.7976 7.3713 2.8143 0.278
LCLC-103H GDSC1; CTRP2 5.7982 8.1239 4.793 5.7556
NCI-H838 GDSC1; CTRP2 5.8267 9.7688 3.9977 9.0294
NCI-H841 GDSC1; CTRP2 5.8538 7.1065 5.3472 3.3206
Lu-134-A GDSC1 5.8666 8.1601 2.5538 1.092
SK-LU-1 GDSC1; CTRP2 5.8778 10.7845 3.5341 10.8584
HCC78 GDSC1; CTRP2 5.9244 9.1946 4.3682 7.2805
NCI-H2286 CTRP2 5.9611 10.177 3.9083 9.1355
Calu-6 GDSC1; CTRP2 5.9679 9.2402 4.3823 7.1352
HCC2108 CTRP2 6.0243 9.3001 4.3998 6.9513
KNS-62 GDSC1; CTRP2 6.0407 9.2218 4.4526 6.6978
NCI-H2196 CTRP2 6.0623 8.245 4.959 4.5278
LC-1/sq-SF CTRP2 6.1606 7.0173 5.6511 1.4422
NCI-H1395 CTRP2 6.179 8.0782 5.1374 3.5604
NCI-H2122 GDSC1; CTRP2 6.2395 9.2635 4.5944 5.7285
COLO 699 CTRP2 6.2644 12.0836 3.2061 11.4564
RERF-LC-Ad1 CTRP2 6.2683 7.6625 5.4135 2.25
Lu-139 GDSC1 6.2883 15.8672 -0.6838 18.092
BEN GDSC1; CTRP2 6.2893 8.6285 4.9504 4.1471
RERF-LC-Ad2 CTRP2 6.4089 9.3237 4.6977 4.9949
A-549 GDSC1; CTRP2 6.605 10.0693 4.4779 5.5781
NCI-H2172 GDSC1; CTRP2 6.7814 10.0006 4.6418 4.6162
HCC1171 CTRP2 6.9437 10.7508 4.3921 5.3886
NCI-H1184 CTRP2 7.1357 13.959 2.9557 10.9075
NCI-H1793 GDSC1; CTRP2 7.2338 13.6983 3.1578 9.9427
Calu-1 CTRP2 7.2553 11.9856 4.0124 6.4603
NCI-H2342 GDSC1; CTRP2 7.4057 13.323 3.4678 8.4278
NCI-H1755 GDSC1; CTRP2 7.4893 9.4783 5.3296 1.113
RERF-LC-MS GDSC1; CTRP2 7.6037 11.9466 4.2697 4.9292
NCI-H196 GDSC1; CTRP2 8.0029 13.128 3.9716 5.5677
LXF 289 GDSC1; CTRP2 8.3928 17.6991 2.0393 12.342
NCI-H441 GDSC1; CTRP2 8.4663 13.5448 4.0689 4.6207
NCI-H2126 CTRP2 8.543 15.5901 3.1588 7.9786
NCI-H460 GDSC1; CTRP2 8.7757 15.4931 3.3561 6.9261
NCI-H2023 GDSC1; CTRP2 12.225 23.6813 1.6889 8.672
Hs 888.Lu CTRP2 6.5831 10.1559 4.4185 5.8618
⏷ Show the Full List of 212 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 5.5975 7.6018 2.6528 0.9041
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.4569 12.2629 1.53 21.7444
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 5.1789 9.2726 3.6623 11.8125
A2780 GDSC1; CTRP2 3.2236 5.308 3.1312 19.1079
SNU-119 CTRP2 3.4055 6.0763 3.1557 18.4554
JHOS-4 GDSC1 3.5064 5.1938 2.535 5.5695
OVSAHO CTRP2 3.6437 7.0743 3.0854 18.0156
OVCAR-3 GDSC1 3.7126 7.6162 1.4911 12.8888
IGROV-1 GDSC1; CTRP2 3.8011 6.7021 3.3896 16.4216
ES-2 GDSC1 4.0319 6.2435 2.4021 5.0482
OVKATE GDSC1 4.1513 6.6451 2.2904 5.5705
Caov-4 GDSC1 4.2466 6.6174 2.3664 4.7679
COV434 CTRP2 4.5736 7.8855 3.7268 13.0095
ONCO-DG-1 CTRP2 4.6139 6.3851 4.3785 10.3715
OC 314 GDSC1; CTRP2 4.6673 6.9871 4.2096 10.8627
Caov-3 CTRP2 4.8176 7.3152 4.2281 10.3887
FU-OV-1 GDSC1; CTRP2 4.9277 11.5972 2.2901 17.8702
COV362 CTRP2 5.0929 7.6729 4.3458 9.217
JHOM-1 CTRP2 5.1147 8.8503 3.8073 11.3633
OAW42 GDSC1; CTRP2 5.1711 6.7889 4.8201 7.1252
Kuramochi GDSC1; CTRP2 5.1951 8.1063 4.2417 9.3932
JHOC-5 CTRP2 5.1957 6.9722 4.7666 7.2709
COV644 CTRP2 5.2138 6.6033 4.9416 6.5369
OVTOKO GDSC1; CTRP2 5.2751 9.8888 3.4486 12.4768
OVCAR-8 GDSC1; CTRP2 5.4721 7.9369 4.5872 7.3272
MCAS CTRP2 5.5397 7.9964 4.6214 7.0326
EFO-27 GDSC1; CTRP2 5.5639 6.2044 5.469 3.543
TOV-112D GDSC1; CTRP2 5.6166 6.9471 5.2009 4.4681
OVK18 GDSC1; CTRP2 5.9779 6.9935 5.5134 2.3639
OV7 CTRP2 6.0386 7.3311 5.3963 2.7355
EFO-21 GDSC1; CTRP2 6.1131 8.0888 5.0789 3.9278
TYK-nu GDSC1; CTRP2 6.1674 8.8184 4.7585 5.1721
SNU-8 CTRP2 6.1972 8.7352 4.8241 4.8419
TOV-21G GDSC1; CTRP2 6.2283 7.3459 5.5399 2.0694
OV56 GDSC1; CTRP2 6.2882 7.6247 5.4471 2.0775
OVCAR-4 GDSC1; CTRP2 6.644 9.6073 4.7346 4.4506
RMG-I GDSC1; CTRP2 6.8213 13.0803 3.151 10.6684
OVISE GDSC1; CTRP2 6.9057 9.9974 4.7315 4.0609
JHOS-2 GDSC1; CTRP2 6.9061 10.0259 4.718 4.1151
OVCAR-5 GDSC1; CTRP2 6.9913 14.0219 2.8147 11.7093
OAW28 GDSC1; CTRP2 7.0896 10.2876 4.7179 3.8515
HEY A8 CTRP2 7.1116 12.1883 3.8101 7.5067
OV-90 GDSC1; CTRP2 7.3236 10.1855 4.918 2.7602
SNU-840 CTRP2 7.3939 14.1987 3.0299 10.1877
ES2 CTRP2 7.8418 10.2369 5.1888 1.2769
SK-OV-3 GDSC1; CTRP2 7.8877 10.9948 4.8841 2.2634
DOV13 GDSC1; CTRP2 8.4588 16.1107 2.8535 9.2506
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 5.3632 7.4912 4.6969 7.1323
P-STS CTRP2 5.364 10.2418 3.3548 12.6677
H-STS CTRP2 5.6189 7.5446 4.9157 5.6347
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 5.8739 7.1111 5.3631 3.2108
Yamato-SS CTRP2 6.1236 8.6076 4.8282 4.9613
Hs 633.T GDSC1 2.3539 5.5086 1.345 19.3581
EW-8 GDSC1 3.0174 8.6885 0.3809 22.7259
SW872 GDSC1 3.1055 6.7955 1.4016 15.7445
SW684 GDSC1 3.2237 5.5626 2.1187 9.8435
A-204 GDSC1; CTRP2 3.2624 6.9433 2.7228 20.4684
KYM-1 GDSC1; CTRP2 3.4085 5.6034 3.275 18.0203
Rh41 GDSC1; CTRP2 3.6804 5.7732 3.5331 16.2589
VA-ES-BJ GDSC1 3.6841 8.4115 1.0723 15.9269
MFH-ino GDSC1 3.787 6.1841 2.2575 6.848
GCT GDSC1; CTRP2 3.8251 7.6693 3.0442 17.6666
Rh30 GDSC1 3.9129 6.9728 1.9625 8.7255
STS-0421 GDSC1 4.072 6.0132 2.5383 3.9324
Rh18 GDSC1; CTRP2 4.1509 6.9251 3.685 14.3088
TE 617.T CTRP2 4.5401 6.6077 4.2205 11.1763
RD GDSC1; CTRP2 4.8306 9.1583 3.3882 13.7402
G-402 GDSC1; CTRP2 4.8438 7.7921 4.0421 11.0617
G-401 GDSC1; CTRP2 4.963 7.8607 4.1299 10.4106
TE 441.T CTRP2 5.1401 9.2728 3.6261 12.0494
HT-1080 GDSC1; CTRP2 5.2375 7.3883 4.6212 7.7466
BT-16 CTRP2 5.2993 6.251 5.1667 5.4392
MES-SA GDSC1; CTRP2 5.3523 6.0544 5.2863 4.8418
TTC-709 CTRP2 5.5604 9.6812 3.8084 10.3711
SK-UT-1 GDSC1; CTRP2 5.6438 8.6826 4.3781 7.8173
Hs 729.T CTRP2 5.8453 9.1129 4.3412 7.5522
Tm87-16 CTRP2 5.9105 8.8871 4.51 6.7127
BT-12 CTRP2 6.0311 6.6874 5.7118 1.424
SK-LMS-1 GDSC1; CTRP2 6.2943 10.4154 4.0635 7.8526
SW982 GDSC1; CTRP2 6.8373 12.8871 3.2593 10.2042
RKN GDSC1; CTRP2 7.3088 9.4431 5.2472 1.5573
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; CTRP2 3.802 7.0327 3.2707 16.8661
NCI-H2452 GDSC1; CTRP2 4.0543 10.0537 2.21 23.2213
NCI-H28 GDSC1; CTRP2 4.2638 6.6018 3.9247 13.0817
NCI-H2052 GDSC1; CTRP2 5.0184 8.8719 3.7054 12.005
MPP 89 GDSC1; CTRP2 5.7007 12.665 2.4435 15.6071
ACC-MESO-1 CTRP2 6.5224 8.0654 5.3991 1.9166
IST-Mes1 GDSC1; CTRP2 7.27 10.5042 4.7345 3.5407
JL-1 CTRP2 8.1979 12.3037 4.4751 3.416
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC1 4.0298 6.337 2.3557 5.4025
LNCaP clone FGC GDSC1; CTRP2 4.2197 6.5848 3.8831 13.365
22Rv1 GDSC1; CTRP2 5.1829 8.5912 3.9971 10.4254
PaCa-3 CTRP2 5.9669 7.6464 5.1779 3.7945
VCaP GDSC1; CTRP2 5.995 8.3002 4.8751 5.0111
DU145 GDSC1; CTRP2 6.1051 8.8461 4.6938 5.5608
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 3.5048 5.7051 3.3576 17.4273
A-253 GDSC1; CTRP2 3.9349 6.1288 3.7187 14.8127
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 3.3003 4.581 2.6743 5.1866
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TMK-1 GDSC1 2.8836 6.7709 1.2198 17.932
SNU-620 CTRP2 3.1005 4.569 3.0843 19.6671
HSC-39 GDSC1 3.1154 4.4431 2.5811 6.6364
GSS CTRP2 3.2647 5.078 3.2097 18.7052
GCIY GDSC1 3.3051 5.3876 2.275 8.3154
SNU-1 GDSC1; CTRP2 3.3783 6.9349 2.8508 19.6562
HGC-27 GDSC1; CTRP2 3.4716 5.4357 3.3763 17.4665
OCUM-1 GDSC1 3.5059 5.3689 2.4474 6.258
RERF-GC-1B GDSC1 3.5509 7.6443 1.3484 14.4754
Fu97 GDSC1; CTRP2 3.6756 7.0033 3.146 17.6965
ECC10 GDSC1; CTRP2 3.7446 5.2151 3.7029 15.4624
Hs 746.T GDSC1; CTRP2 3.8039 6.8093 3.3547 16.5446
SK-GT-2 GDSC1 3.8083 7.667 1.5402 12.2118
NUGC-4 GDSC1; CTRP2 3.8815 5.9516 3.7086 15.0117
IM95 GDSC1; CTRP2 3.9258 7.6415 3.1615 16.9399
NCI-N87 GDSC1; CTRP2 3.9925 7.7987 3.1656 16.7439
SNU-16 GDSC1; CTRP2 4.0282 5.7355 3.92 13.805
MKN74 CTRP2 4.105 9.511 2.5138 18.9829
TGBC11TKB GDSC1 4.2328 6.7314 2.3035 5.2647
23132/87 GDSC1; CTRP2 4.2375 6.1637 4.0386 12.7379
SNU-216 CTRP2 4.3694 7.7939 3.5583 14.2067
KE-39 CTRP2 4.6056 9.5889 2.9659 15.9758
SNU-601 CTRP2 4.6261 7.2341 4.0642 11.5399
SCH GDSC1 4.6953 7.5858 2.1968 4.9464
SNU-5 GDSC1; CTRP2 4.7015 7.2463 4.1375 11.0515
MKN1 GDSC1; CTRP2 4.8874 6.1503 4.7513 9.4598
AGS GDSC1; CTRP2 5.062 7.0533 4.5937 8.3041
KATO III GDSC1; CTRP2 5.2596 7.8434 4.4293 8.4727
SNU-719 CTRP2 5.33 7.8304 4.5034 8.0023
GSU CTRP2 5.6127 6.8116 5.2606 4.2348
RF-48 GDSC1 5.6709 7.3581 2.7719 0.4401
SH-10-TC CTRP2 5.7182 6.9963 5.2753 3.9229
HuG1-N CTRP2 5.8866 9.146 4.3602 7.3894
ECC12 CTRP2 5.9609 7.8559 5.0682 4.2675
MKN28 GDSC1 6.3892 8.5971 2.602 0.5796
MKN7 GDSC1; CTRP2 6.6389 9.9412 4.5665 5.1542
LMSU CTRP2 6.6589 9.5093 4.7936 4.1837
MKN45 GDSC1; CTRP2 7.0461 12.7494 3.4857 8.9336
SNU-668 CTRP2 8.1165 11.8825 4.6179 2.9822
NUGC-3 GDSC1; CTRP2 8.1233 10.0574 5.3937 0.5283
SNU-1077 CTRP2 4.8607 7.5561 4.1658 10.5241
SNG-M GDSC1; CTRP2 4.8911 7.8785 4.05 10.9113
SNU-685 CTRP2 6.3563 9.9051 4.3674 6.4687
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1 2.0493 4.5573 1.4736 19.9155
K5 GDSC1 3.0747 4.7153 2.4098 8.1416
ASH-3 GDSC1 3.3213 5.8925 2.0361 10.1274
HTC-C3 GDSC1 3.5436 7.179 1.5749 12.8532
8305C GDSC1; CTRP2 3.7446 6.8042 3.2925 16.9482
WRO GDSC1 3.7668 6.3065 2.1822 7.491
KMH-2 GDSC1 3.7949 6.6322 2.0426 8.4782
TT GDSC1; CTRP2 3.7994 7.6688 3.0175 17.8396
CAL-62 GDSC1; CTRP2 4.3204 6.0537 4.1604 12.0451
B-CPAP GDSC1; CTRP2 4.8245 7.5599 4.1273 10.7703
BHT-101 GDSC1; CTRP2 5.0156 8.3028 3.9745 10.9127
SW579 CTRP2 5.1683 8.1856 4.1781 9.7169
8505C GDSC1; CTRP2 5.3847 11.7254 2.637 15.516
ML-1 [Human leukemia] GDSC1; CTRP2 5.4623 9.3275 3.8956 11.7984
FTC-238 CTRP2 5.7353 8.4822 4.5592 6.8663
CGTH-W-1 GDSC1; CTRP2 5.7511 8.3672 4.6304 6.5349
FTC-133 GDSC1; CTRP2 6.2709 7.7507 5.3719 2.4185
TT2609-C02 GDSC1; CTRP2 6.3557 9.3817 4.6275 5.3812
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-06A GDSC1 2.2658 5.3472 1.3351 19.8423
BB30-HNC GDSC1 2.3406 6.1189 1.0401 21.5361
HO-1-u-1 GDSC1 2.7651 6.6503 1.1736 18.7483
SCC-15 GDSC1 2.7819 3.7761 2.5675 8.2479
SKN-3 GDSC1 2.8361 6.2761 1.4227 16.6752
KON GDSC1 2.8367 6.2353 1.4434 16.5219
PCI-38 GDSC1 2.8934 6.1368 1.5431 15.5529
Ca9-22 GDSC1 2.9042 4.7805 2.2208 10.3238
JHU-011 GDSC1 2.9864 5.2745 2.0536 11.2801
NCI-H3118 GDSC1 3.0223 5.7055 1.8721 12.5403
PCI-04B GDSC1 3.0451 6.6324 1.4307 15.7702
BICR 78 GDSC1 3.0546 6.8174 1.3467 16.3408
JHU-022 GDSC1 3.0622 5.6589 1.9305 11.9309
BICR 10 GDSC1 3.3031 8.3632 0.7856 19.1857
OSC-19 GDSC1 3.3356 5.7161 2.1362 9.2938
KOSC-2 GDSC1 3.3933 7.5515 1.2663 15.6249
BB49-HNC GDSC1 3.4727 6.2726 1.9703 10.1
PCI-15A GDSC1 3.5144 5.4214 2.428 6.3824
DOK GDSC1 3.5328 7.7888 1.2617 15.1544
SCC-4 GDSC1; CTRP2 3.5661 6.6895 3.1396 18.0361
YD-10B CTRP2 3.5812 6.6094 3.1832 17.8302
JHU-029 GDSC1 3.6219 6.3249 2.0625 8.8798
HO-1-N-1 GDSC1 3.6617 7.8586 1.3302 14.2188
OSC-20 GDSC1 3.6633 7.0138 1.7522 11.1178
SAT [Human HNSCC] GDSC1 3.8692 6.5878 2.1196 7.6595
LB771-HNC GDSC1 3.9348 6.4313 2.2437 6.5168
SAS GDSC1 4.0656 6.2762 2.4091 4.9074
PCI-30 GDSC1 4.1648 7.1179 2.0722 7.1664
UPCI-SCC-090 GDSC1 4.1682 6.4062 2.4152 4.602
Detroit 562 GDSC1; CTRP2 4.3526 8.6793 3.1443 15.8886
BICR 18 CTRP2 4.4099 12.1683 1.5325 21.8484
CAL-33 GDSC1; CTRP2 4.6921 7.1916 4.1509 11.0246
SCC-25 GDSC1; CTRP2 4.8795 8.4504 3.7721 12.064
BHY GDSC1; CTRP2 4.995 9.1444 3.5517 12.6882
SNU-1076 CTRP2 5.0153 7.3588 4.4111 9.1497
YD-8 CTRP2 5.205 7.8548 4.3708 8.8418
HSC-2 GDSC1; CTRP2 5.2261 6.5735 4.9666 6.4067
SNU-1214 CTRP2 5.2582 9.2053 3.7689 11.1942
SNU-899 CTRP2 5.3595 6.9675 4.9357 6.1761
FaDu GDSC1; CTRP2 5.4632 6.1377 5.3824 4.1587
PE/CA-PJ15 GDSC1; CTRP2 5.4706 8.1229 4.4953 7.7106
BICR 6 CTRP2 5.5813 6.3293 5.4403 3.6031
PE/CA-PJ49 CTRP2 5.5903 7.7054 4.8106 6.1348
SCC-9 GDSC1; CTRP2 5.8909 8.3607 4.756 5.7192
PE/CA-PJ34 (clone C12) CTRP2 5.9326 7.9725 4.9857 4.6709
CAL-27 GDSC1; CTRP2 6.0082 8.649 4.7118 5.6713
PE/CA-PJ41 (clone D2) CTRP2 6.0498 7.2649 5.4387 2.5355
HSC-4 GDSC1; CTRP2 6.0746 11.4489 3.3673 11.1598
BICR 16 CTRP2 6.1632 9.1082 4.6104 5.8021
HSC-3 GDSC1; CTRP2 6.6524 10.8218 4.1415 6.8959
BICR 56 CTRP2 6.881 10.3624 4.5367 4.893
BICR 31 CTRP2 6.9651 9.8815 4.8283 3.584
SNU-1041 CTRP2 7.1354 14.6841 2.5967 12.3077
SNU-1066 CTRP2 7.8584 9.5061 5.492 0.426
SNU-46 CTRP2 8.4716 10.5615 5.3487 0.4755
BICR 22 GDSC1; CTRP2 9.44 24.8922 -0.7212 19.2152
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
5637 GDSC1; CTRP2 3.0053 5.8191 2.7865 21.0061
BFTC-905 GDSC1 3.084 5.4645 2.0464 10.9457
SW780 GDSC1 3.6022 5.9325 2.2422 7.5475
253J CTRP2 3.6371 5.6083 3.5222 16.4326
JMSU-1 CTRP2 3.8161 7.0768 3.2693 16.8319
253J-BV CTRP2 4.0125 6.1545 3.7959 14.2982
U-BLC1 CTRP2 4.5777 6.4651 4.3119 10.7251
CAL-29 GDSC1; CTRP2 4.6698 6.9931 4.2098 10.8556
TCCSUP GDSC1; CTRP2 4.7771 7.2796 4.2017 10.5993
VM-CUB-1 CTRP2 4.8211 6.6272 4.5148 9.2646
647V GDSC1; CTRP2 4.8492 7.8417 4.025 11.117
BC-3C CTRP2 5.1406 6.674 4.8357 7.1469
SW1710 GDSC1; CTRP2 5.1753 10.2713 3.1691 13.8402
RT-112 GDSC1; CTRP2 5.2089 8.6739 3.9817 10.4285
UM-UC-1 CTRP2 5.3347 7.446 4.6903 7.228
639V GDSC1; CTRP2 5.3504 6.8579 4.9754 6.0413
HT-1197 GDSC1; CTRP2 5.6328 6.0946 5.5806 2.9269
T24 GDSC1; CTRP2 6.012 7.4069 5.3359 3.0412
J82 GDSC1; CTRP2 6.0782 8.3107 4.9393 4.5803
KMBC-2 CTRP2 6.1657 10.2761 4.0288 8.2375
UM-UC-3 GDSC1; CTRP2 6.364 9.8416 4.4052 6.2969
SCaBER CTRP2 6.4824 8.2221 5.2955 2.3963
KU-19-19 GDSC1; CTRP2 6.695 16.0249 1.5854 16.8251
HT-1376 GDSC1; CTRP2 7.6972 15.9852 2.3752 12.2099
RT-4 GDSC1; CTRP2 8.1323 13.6624 3.8032 6.0516
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NEC8 GDSC1 1.26 3.1894 1.1064 26.7632
PA-1 GDSC1 2.0949 3.2564 2.0001 15.9569
OVMIU GDSC1 2.1327 5.6285 1.0725 22.3022
Ca Ski GDSC1 2.5709 13.2622 -2.2872 34.6696
BPH-1 GDSC1 2.5935 5.9683 1.3515 18.2279
HEY GDSC1 2.7906 4.7916 2.108 11.6863
SKN GDSC1 2.9963 6.4388 1.4845 15.5697
C-4-I GDSC1 3.0165 6.7487 1.3478 16.4841
HEC-1 GDSC1 3.0822 4.3958 2.5741 6.8276
JAR GDSC1 3.1602 4.7232 2.4824 7.2307
DoTc2 4510 GDSC1 3.2205 4.5741 2.6094 5.998
SW954 GDSC1 3.2245 4.8816 2.4594 7.1633
ACC-OV7 GDSC1 3.3615 7.0723 1.4796 14.207
SW962 GDSC1 3.443 5.6916 2.2364 8.1277
SiSo GDSC1 3.4503 5.2112 2.4821 6.1727
KGN GDSC1 3.5095 5.7786 2.2462 7.824
OVCA420 GDSC1 3.5249 5.1604 2.5659 5.2666
NT2-D1 GDSC1 3.5472 5.4667 2.431 6.2511
MS751 GDSC1 3.6431 4.9886 2.7387 3.5587
CAL-39 GDSC1 3.689 5.5748 2.4849 5.3849
ME-180 GDSC1 3.7079 7.433 1.5785 12.264
TC-YIK GDSC1 3.7308 5.2941 2.6523 3.9714
SW756 GDSC1 3.7415 6.1731 2.2291 7.2064
HT-3 GDSC1 3.7632 5.7651 2.4458 5.4655
PWR-1E GDSC1 3.7735 8.9588 0.8704 16.9496
PEO1 GDSC1 3.774 5.8274 2.4231 5.6086
DSH1 GDSC1 3.7992 9.0429 0.8488 17.0005
SKG-IIIa GDSC1 3.8927 6.177 2.3376 5.9207
OV17R GDSC1 3.957 7.4686 1.7512 10.1798
OMC-1 [Human cervical carcinoma] GDSC1 4.0411 6.142 2.4568 4.6147
JEG-3 GDSC1 4.0605 6.0363 2.5199 4.0966
UWB1.289 GDSC1 4.1283 6.6139 2.2898 5.635
OVCA433 GDSC1 4.1552 6.5213 2.352 5.1021
SiHa GDSC1 4.304 5.739 2.8004 1.6388
JHOS-3 GDSC1 4.4712 6.1785 2.6995 1.9937
C-33 A GDSC1 4.5591 8.0634 1.8861 7.4886
LB831-BLC GDSC1 4.8933 11.7421 0.3387 16.6441
HeLa GDSC1; CTRP2 6.5738 10.1967 4.3912 5.9908
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug

References

1 Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion. Mol Cancer Ther. 2009 Oct;8(10):2894-902.