General Information of Drug (ID: DMWA8B0)

Drug Name
JZL184
Synonyms JZL 184; JZL-184
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 520.5
Logarithm of the Partition Coefficient (xlogp) 4.2
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 9
Chemical Identifiers
Formula
C27H24N2O9
IUPAC Name
(4-nitrophenyl) 4-[bis(1,3-benzodioxol-5-yl)-hydroxymethyl]piperidine-1-carboxylate
Canonical SMILES
C1CN(CCC1C(C2=CC3=C(C=C2)OCO3)(C4=CC5=C(C=C4)OCO5)O)C(=O)OC6=CC=C(C=C6)[N+](=O)[O-]
InChI
InChI=1S/C27H24N2O9/c30-26(38-21-5-3-20(4-6-21)29(32)33)28-11-9-17(10-12-28)27(31,18-1-7-22-24(13-18)36-15-34-22)19-2-8-23-25(14-19)37-16-35-23/h1-8,13-14,17,31H,9-12,15-16H2
InChIKey
SEGYOKHGGFKMCX-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
25021165
ChEBI ID
CHEBI:95015
CAS Number
1101854-58-3
TTD ID
D0G0MZ

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Monoglyceride lipase (MAGL) TTZ963I MGLL_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U2OS CTRP1 7.0119 10.768 3.75 7.159
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MCF-7 CTRP1 5.9023 11.3489 2.6963 18.3864
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SF295 CTRP1 7.1889 8.4956 4.7867 0.2992
GaMG CTRP1 7.3125 8.9627 4.6664 0.6331
LN-229 CTRP1 7.3245 9.1542 4.6 0.9031
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-6 CTRP1 6.2127 7.4731 4.764 1.3141
MFE-319 CTRP1 6.4584 9.2296 4.1203 5.6656
JHUEM-2 CTRP1 6.4916 8.6509 4.4033 3.3665
HEC-265 CTRP1 6.6593 7.7403 4.8557 0.3596
HEC-108 CTRP1 6.8534 7.9336 4.8601 0.2435
HEC-59 CTRP1 7.0888 8.5861 4.7158 0.5986
HEC-251 CTRP1 7.4208 8.7424 4.785 0.2148
HEC-151 CTRP1 7.82 17.4738 1.0931 20.9141
KLE CTRP1 7.9643 9.995 4.5457 0.6534
Ishikawa (Heraklio) 02 ER- CTRP1 6.3102 7.5798 4.7675 1.1451
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NU-DUL-1 CTRP1 3.7333 33.3634 -10.1158 46.2757
PL21 CTRP1 5.3737 8.0725 3.9124 10.9772
BL-70 CTRP1 5.6476 6.9263 4.683 3.2088
WSU-DLCL2 CTRP1 5.7975 11.5898 2.4951 20.0775
GDM-1 CTRP1 5.8903 10.2436 3.2348 14.5906
NOMO-1 CTRP1 5.908 7.7392 4.4686 4.2781
Ku812 CTRP1 5.9204 7.7241 4.4838 4.1161
SKM-1 CTRP1 6.0677 9.0204 3.9631 8.0838
U-937 CTRP1 6.238 10.784 3.2259 13.4405
THP-1 CTRP1 6.265 16.0356 0.6489 27.3247
HT CTRP1 6.3329 8.405 4.4224 3.5717
MC116 CTRP1 6.3719 7.2239 4.9311 0.2697
SU-DHL-4 CTRP1 6.4337 15.9145 0.8399 26.056
MOLM-16 CTRP1 6.4463 11.8083 2.8754 15.2654
LP-1 CTRP1 6.6447 12.3106 2.7723 15.3183
AMO1 CTRP1 6.7353 7.9433 4.8115 0.4749
SU-DHL-5 CTRP1 6.9587 8.3328 4.7572 0.529
P3HR-1 CTRP1 7.0093 8.4083 4.7495 0.5231
EJM CTRP1 7.0405 8.947 4.557 1.4176
RPMI-8226 CTRP1 7.1469 13.0765 2.7499 13.9355
OCI-Ly10 CTRP1 7.6683 18.9917 0.2446 24.6447
KE-97 CTRP1 7.6879 8.9135 4.8196 0.0931
OCI-AML-3 CTRP1 8.2005 21.9142 -0.8003 26.5881
KMS-11 CTRP1 8.638 17.6977 1.5394 16.7715
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RCC10RGB CTRP1 6.0805 8.6779 4.1364 6.5834
VMRC-RCW CTRP1 6.3373 10.0104 3.6715 9.6468
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW48 CTRP1 5.8663 8.0727 4.2813 5.9988
LS513 CTRP1 5.9036 9.6516 3.537 12.1668
MDST8 CTRP1 5.9657 7.9832 4.3909 4.7696
HCT 8 CTRP1 6.0617 7.6642 4.5986 2.8196
SNU-C4 CTRP1 6.2319 13.6163 1.8247 22.3083
SW480 CTRP1 6.2564 8.5066 4.3302 4.4907
HCT 116 CTRP1 6.2667 8.7551 4.2212 5.3512
COLO205 CTRP1 6.3392 7.6701 4.7444 1.2458
LoVo CTRP1 6.4027 8.6285 4.3622 3.8803
DLD-1 CTRP1 6.4978 7.3149 4.9459 0.1637
KM12 CTRP1 6.5205 7.9237 4.7271 1.1016
SW403 CTRP1 6.5261 8.5676 4.4592 2.8791
RCM-1 [Human ESC] CTRP1 6.5342 9.392 4.092 5.6979
SW948 CTRP1 6.6113 8.1229 4.6892 1.2041
CW-2 CTRP1 6.616 8.5644 4.5084 2.3584
SNU-61 CTRP1 6.6623 8.6159 4.5104 2.2633
COLO 320 CTRP1 6.6738 9.9253 3.9314 6.613
HT-55 CTRP1 6.6738 8.2467 4.6684 1.2435
HT115 CTRP1 6.7311 9.3109 4.2451 4.0447
SNU-81 CTRP1 6.7727 8.8606 4.4633 2.3939
SK-CO-1 CTRP1 6.784 8.7084 4.5327 1.9173
RKO CTRP1 6.7899 9.3702 4.2518 3.8702
SNU-1040 CTRP1 6.9988 8.8649 4.5707 1.3919
SW620 CTRP1 7.1102 12.4752 3.0124 12.28
CL-40 CTRP1 7.1498 8.6109 4.7308 0.5
CL-34 CTRP1 7.1776 8.9559 4.6136 0.9738
LS411N CTRP1 7.2011 8.2672 4.8692 0.1134
C2BBe1 CTRP1 7.2823 9.3186 4.5188 1.3429
COLO 678 CTRP1 7.3032 9.9792 4.2608 2.858
NCI-H508 CTRP1 7.3626 15.73 1.6177 19.7665
LS180 CTRP1 7.3647 8.8329 4.7332 0.3719
SNU-175 CTRP1 7.4468 9.2983 4.5963 0.8176
SNU-C5 CTRP1 7.4821 9.1781 4.6544 0.5656
GP2d CTRP1 7.6726 9.0749 4.7604 0.1902
SNU-C2A CTRP1 7.673 13.2204 3.0235 10.6958
LS123 CTRP1 7.7499 14.0161 2.7005 12.5966
HT-29 CTRP1 9.8867 23.5656 -0.4242 21.6891
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-6 CTRP1 6.4405 7.2085 4.9621 0.1453
Hep-G2 CTRP1 6.6443 8.4769 4.5598 1.9615
SNU-449 CTRP1 6.974 10.3664 3.9108 6.0297
SNU-398 CTRP1 7.729 9.641 4.5826 0.6686
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H82 CTRP1 4.8377 5.6549 4.6326 6.9751
COR-L51 CTRP1 5.2839 7.9094 3.921 11.2625
NCI-H1930 CTRP1 5.6434 8.004 4.1553 7.8335
NCI-H2110 CTRP1 5.7229 7.5402 4.4393 5.0814
NCI-H1694 CTRP1 5.8246 11.1258 2.747 18.3388
NCI-H596 CTRP1 5.826 8.1084 4.2361 6.5163
NCI-H1963 CTRP1 5.8753 7.6847 4.473 4.3337
NCI-H1568 CTRP1 5.9727 8.6901 4.0569 7.5893
NCI-H1435 CTRP1 5.9894 8.3742 4.2204 6.1444
NCI-H2286 CTRP1 6.0069 8.0391 4.3912 4.651
CAL-12T CTRP1 6.0204 8.3573 4.2492 5.8079
T3M-10 CTRP1 6.0819 10.5239 3.2397 13.8714
HCC2935 CTRP1 6.1289 8.7448 4.1368 6.4375
NCI-H2029 CTRP1 6.2661 8.9064 4.1499 5.9383
SHP-77 CTRP1 6.3757 8.9285 4.2086 5.1677
LXF 289 CTRP1 6.3804 9.9692 3.7205 9.1212
ChaGo-K-1 CTRP1 6.3911 10.309 3.5646 10.3315
NCI-H1836 CTRP1 6.4139 9.6232 3.9075 7.5099
NCI-H727 CTRP1 6.426 8.5876 4.3942 3.5795
HCC1359 CTRP1 6.4284 7.3907 4.8926 0.3754
BEN CTRP1 6.4481 7.7843 4.7495 1.0651
HCC827 CTRP1 6.4592 8.8006 4.3175 4.0983
NCI-H23 CTRP1 6.491 9.2869 4.114 5.6324
NCI-H1944 CTRP1 6.4978 9.953 3.8062 8.0881
LCLC-103H CTRP1 6.5549 7.6748 4.8383 0.5018
NCI-H1373 CTRP1 6.5688 8.5447 4.4921 2.5592
COR-L279 CTRP1 6.5946 8.1388 4.6749 1.3097
NCI-H1876 CTRP1 6.5971 10.6283 3.551 9.817
NCI-H2126 CTRP1 6.6143 8.01 4.7353 0.9431
NCI-H2172 CTRP1 6.6446 9.8956 3.9271 6.7235
HCC44 CTRP1 6.6541 9.2846 4.2128 4.4611
HARA [Human squamous cell lung carcinoma] CTRP1 6.696 8.9579 4.3811 3.1114
NCI-H1048 CTRP1 6.7124 8.9214 4.4057 2.9029
NCI-H1666 CTRP1 6.7399 11.2179 3.3651 10.8143
NCI-H2081 CTRP1 6.7469 9.5488 4.1476 4.75
VMRC-LCD CTRP1 6.7664 8.7503 4.5065 2.1151
HCC1195 CTRP1 6.7672 8.8449 4.4671 2.3771
EBC-1 CTRP1 6.7717 10.2102 3.8601 6.9193
NCI-H2009 CTRP1 6.7957 9.0979 4.3738 2.9727
HCC4006 CTRP1 6.804 9.4815 4.2104 4.1487
NCI-H460 CTRP1 6.8095 8.2051 4.7441 0.7027
Lu-65 CTRP1 6.8141 8.8736 4.4788 2.2207
NCI-H2023 CTRP1 6.8178 10.1868 3.8992 6.499
COLO 668 CTRP1 6.8264 9.1079 4.3857 2.8328
HCC78 CTRP1 6.8413 10.3776 3.8255 7.0095
NCI-H810 CTRP1 6.8577 8.2947 4.7303 0.7228
NCI-H2405 CTRP1 6.8903 9.6404 4.1883 4.1299
LC-1/sq-SF CTRP1 6.9623 8.4802 4.7039 0.7509
COR-L88 CTRP1 6.9842 8.5491 4.6869 0.8088
NCI-H1793 CTRP1 6.9878 9.5197 4.2938 3.1796
SCLC-21H CTRP1 6.9963 8.4279 4.7371 0.5812
HCC1833 CTRP1 7.0276 10.4942 3.8845 6.1032
NCI-H1573 CTRP1 7.0276 9.5405 4.3057 3.0254
NCI-H1755 CTRP1 7.0553 8.8606 4.5976 1.1799
NCI-H2122 CTRP1 7.0589 8.7269 4.6507 0.9095
NCI-H441 CTRP1 7.0646 9.4896 4.3462 2.6872
NCI-H2030 CTRP1 7.0745 9.9621 4.1485 4.0454
COR-L23 CTRP1 7.0891 8.5568 4.7267 0.5558
NCI-H1437 CTRP1 7.1117 8.9739 4.5782 1.2192
NCI-H2141 CTRP1 7.1318 8.7949 4.6555 0.8209
DMS 273 CTRP1 7.1501 8.9957 4.5866 1.1349
NCI-H841 CTRP1 7.2047 13.9855 2.3524 16.244
NCI-H1781 CTRP1 7.2147 8.7361 4.7106 0.5318
COLO 699 CTRP1 7.22 9.42 4.4504 1.8002
RERF-LC-KJ CTRP1 7.2859 8.853 4.6959 0.5397
NCI-H661 CTRP1 7.3126 10.1637 4.1877 3.3281
Sq-1 CTRP1 7.3401 8.8584 4.7148 0.442
DV-90 CTRP1 7.3996 9.3576 4.5544 1.0454
SK-LU-1 CTRP1 7.4081 9.5111 4.4991 1.309
NCI-H650 CTRP1 7.4164 8.9226 4.7207 0.3838
NCI-H3255 CTRP1 7.4544 9.0587 4.6867 0.4711
LCLC-97TM1 CTRP1 7.4825 9.9077 4.3762 1.8891
HCC33 CTRP1 7.4827 8.9335 4.7413 0.2968
Lu-99 CTRP1 7.496 8.6554 4.8403 0.0983
NCI-H1915 CTRP1 7.4976 9.033 4.712 0.3708
Calu-3 CTRP1 7.4991 9.4778 4.5505 0.9737
NCI-H358 CTRP1 7.5202 9.5718 4.5238 1.0774
NCI-H1299 CTRP1 7.5205 13.2951 2.8921 11.9634
NCI-H1105 CTRP1 7.5512 9.12 4.7012 0.3768
NCI-H2342 CTRP1 7.5723 10.4678 4.1907 2.883
NCI-H1975 CTRP1 7.6606 9.3079 4.6757 0.3997
NCI-H522 CTRP1 7.6796 9.3524 4.667 0.416
NCI-H1792 CTRP1 7.7023 9.2215 4.7209 0.2648
KNS-62 CTRP1 7.7215 9.0719 4.7783 0.1461
EPLC-272H CTRP1 7.735 9.6155 4.5942 0.6229
Calu-6 CTRP1 7.851 9.2867 4.7508 0.1624
NCI-H1355 CTRP1 7.8608 9.7014 4.6113 0.4947
HCC2108 CTRP1 7.8904 9.4579 4.7067 0.235
A-549 CTRP1 8.048 9.8214 4.6381 0.3373
HCC15 CTRP1 8.2892 15.9532 2.1361 14.5509
NCI-H2073 CTRP1 9.0807 17.0978 2.098 12.9086
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-140 CTRP1 6.1361 9.3173 3.8671 8.6725
KYSE-410 CTRP1 6.5397 9.0016 4.2737 4.2523
KYSE-450 CTRP1 6.6523 8.8607 4.3998 3.0617
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RMG-I CTRP1 6.2869 11.1143 3.0997 14.2092
SNU-840 CTRP1 6.4065 9.5941 3.9165 7.4585
OVCAR-4 CTRP1 6.4584 9.0818 4.1886 5.1185
OV-90 CTRP1 6.5303 8.287 4.5821 2.0025
COV318 CTRP1 6.6237 7.621 4.8849 0.2814
COV644 CTRP1 6.891 13.0023 2.6099 15.6043
HEY A8 CTRP1 6.9138 9.8395 4.1132 4.6386
OAW42 CTRP1 6.9995 8.1983 4.8211 0.2876
EFO-27 CTRP1 7.0366 9.1618 4.4685 1.9442
A2780 CTRP1 7.0416 9.0916 4.4995 1.7494
OVMANA CTRP1 7.1234 8.5082 4.7577 0.422
RMUG-S CTRP1 7.207 14.5829 2.065 17.8854
JHOC-5 CTRP1 7.3223 10.8092 3.9126 5.2407
IGROV-1 CTRP1 7.347 10.5743 4.0293 4.3587
OV7 CTRP1 7.3629 8.917 4.7025 0.47
OVCAR-8 CTRP1 7.401 13.4129 2.7589 13.1582
JHOS-4 CTRP1 7.5614 9.097 4.7131 0.339
SK-OV-3 CTRP1 7.5721 9.046 4.7347 0.2789
EFO-21 CTRP1 7.6877 9.383 4.6592 0.4352
OVKATE CTRP1 7.9626 16.7806 1.5265 18.5461
JHOM-1 CTRP1 8.1114 15.364 2.2989 14.0817
COV434 CTRP1 8.1127 10.472 4.4298 0.9926
COV362 CTRP1 8.4905 18.546 1.0377 19.4208
Caov-3 CTRP1 8.5279 15.8002 2.3578 12.7304
TYK-nu CTRP1 9.1686 18.8186 1.3536 16.4057
OVK18 CTRP1 9.2072 19.9599 0.8406 18.5561
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Panc 03.27 CTRP1 6.3447 8.3743 4.4431 3.3847
HuP-T4 CTRP1 6.3641 8.5676 4.3671 3.9321
Capan-2 CTRP1 6.8008 10.4592 3.7626 7.6025
CFPAC-1 CTRP1 6.9874 9.4561 4.3208 2.9925
KP-3 CTRP1 7.0689 11.8156 3.2977 10.3764
HPAC CTRP1 7.2191 8.8827 4.6585 0.7353
PaTu 8902 CTRP1 7.3359 8.5524 4.8198 0.1681
SUIT-2 CTRP1 7.3362 8.8864 4.7033 0.4829
Panc 10.05 CTRP1 7.4712 9.499 4.5308 1.0899
QGP-1 CTRP1 7.4734 9.1135 4.6743 0.5015
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP1 6.1949 8.1557 4.454 3.6481
NCI-H28 CTRP1 7.4257 10.1458 4.2521 2.7198
NCI-H2052 CTRP1 7.7113 9.6867 4.5589 0.7705
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaCa-3 CTRP1 6.4294 7.5151 4.8465 0.5738
Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-MEL-28 CTRP1 6.2801 7.1856 4.9087 0.4227
SK-MEL-5 CTRP1 6.8021 7.9632 4.8304 0.3618
Hs 936.T CTRP1 6.8374 7.8191 4.8939 0.1648
SK-MEL-1 CTRP1 6.9198 8.2836 4.7598 0.5465
A-375 CTRP1 7.1477 9.444 4.4063 2.1683
Hs 852.T CTRP1 7.2249 8.833 4.6792 0.6454
COLO 741 CTRP1 7.2784 8.9572 4.6548 0.7045
G-361 CTRP1 7.3562 8.7948 4.7434 0.3458
Hs 944.T CTRP1 7.5512 9.1807 4.6798 0.4411
⏷ Show the Full List of 9 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-401 CTRP1 6.6339 9.6771 4.0216 6.0026
RKN CTRP1 7.3581 8.6126 4.8071 0.1871
HT-1080 CTRP1 7.4902 9.4551 4.5553 0.9598
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Fu97 CTRP1 6.9598 8.9679 4.511 1.7934
AGS CTRP1 7.0859 27.7618 -4.5436 36.2386
MKN74 CTRP1 7.1968 9.2397 4.5117 1.4802
MKN7 CTRP1 7.2146 8.8866 4.6552 0.7527
SH-10-TC CTRP1 7.4075 8.5731 4.8375 0.1193
NUGC-4 CTRP1 7.5023 9.2909 4.6212 0.6753
SNG-M CTRP1 7.8097 9.425 4.6892 0.3013
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-9 CTRP1 7.1242 8.9562 4.5906 1.1415
HSC-2 CTRP1 7.1392 8.6091 4.7273 0.5196
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RT-4 CTRP1 5.9389 7.9415 4.393 4.8281
KMBC-2 CTRP1 6.439 8.9162 4.2529 4.6551
UM-UC-3 CTRP1 6.6327 8.4142 4.5803 1.846
HT-1376 CTRP1 7.1457 11.6725 3.4138 9.3243
5637 CTRP1 7.3909 11.9575 3.4336 8.5557

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5207).
2 Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. Nat Chem Biol. 2009 Jan;5(1):37-44.