Details of the Drug

General Information of Drug (ID: DMWCJ1F)

Drug Name
OT-58
Indication
Disease Entry ICD 11 Status REF
Homocystinuria 5C50.B Phase 1/2 [1]
Drug Type
Recombinant protein
Cross-matching ID
TTD ID
D87TMY

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cystathionine beta-synthase (CBS) TTVZJ7G CBS_HUMAN Replacement [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03406611) OT-58 as an Enzyme Therapy for Patients With Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency. U.S. National Institutes of Health.
2 Classical homocystinuria: From cystathionine beta-synthase deficiency to novel enzyme therapies. Biochimie. 2020 Jun;173:48-56.