Details of the Drug

General Information of Drug (ID: DMWIAUK)

Drug Name
ReN-1820
Synonyms TrkAd5; HNGF, ReNeuron; Human nerve growth factor, ReNeuron; HNGF, Enact/University of Bristol; Human nerve growth factor, Enact/University of Bristol
Indication
Disease Entry ICD 11 Status REF
Cystitis GC00 Terminated [1]
Cross-matching ID
TTD ID
D0M9FF

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Low-affinity nerve growth factor receptor (NGFR) TTEDJN4 TNR16_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Cystitis
ICD Disease Classification GC00
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Low-affinity nerve growth factor receptor (NGFR) DTT NGFR 5.08E-01 0.38 0.37
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017720)
2 Phosphorylation of Extracellular Signal-Regulated Kinases (pERK1/2) in Bladder Afferent Pathways with Cyclophosphamide (CYP)-Induced Cystitis. Neuroscience. 2009 November 10; 163(4): 1353-1362.