Details of the Drug

General Information of Drug (ID: DMWIHR6)

• Drug Name: GLPG-0187
• Synonyms: IRAMs (bone metastases), Galapagos; IRAMs (bone metastases), ProStrakan; Alpha-1/beta-3 integrin antagonists (bone metastases), Galapagos; Alpha-1/beta-3 integrin antagonists (bone metastases), ProStrakan

Indication

Disease Entry	ICD 11	Status	REF
Bone metastases	2D50	Phase 1	[1]

• Chemical Identifiers:
  Formula: C29H37N7O5S
  Canonical SMILES: CC1=C(N=C(N=C1N2CCC(CC2)C3=NC4=C(CCCN4)C=C3)C)NCC(C(=O)O)NS(=O)(=O)C5=CC=C(C=C5)OC
  InChI: InChI=1S/C29H37N7O5S/c1-18-26(31-17-25(29(37)38)35-42(39,40)23-9-7-22(41-3)8-10-23)32-19(2)33-28(18)36-15-12-20(13-16-36)24-11-6-21-5-4-14-30-27(21)34-24/h6-11,20,25,35H,4-5,12-17H2,1-3H3,(H,30,34)(H,37,38)(H,31,32,33)/t25-/m0/s1
  InChIKey: CXHCNOMGODVIKB-VWLOTQADSA-N
• Cross-matching ID:
  PubChem CID: 53340771
  ChEBI ID: CHEMBL3319236
  CAS Number: 1320346-97-1
  UNII: 43A5P87Z4T
  DrugBank ID: DB12297
  TTD ID: D01TJY
• Drug-Molecule Activity Atlas (DMA)NEW: Click to Jump to the Detailed DMA Information of This Drug

References

• [1] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026321)