Details of the Drug

General Information of Drug (ID: DMWJ6PT)

Drug Name
Tyrophostins
Synonyms
CP-2005; Tyrophostins (cancer); WP-1130; Degrasyns (cancer), Callisto/MD Anderson Cancer Center; Jak2 and Bcr/Abl protein destabiliser (chronic myelogenous leukemia), MD Anderson Cancer Center; Tyrophostins (cancer), Callisto/MD Anderson Cancer Center; C-Myc/Bcr-Abl/Jak-2 inhibitors (cancer), MD Anderson Cancer Center/Callisto
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Investigative [1]
Structure 3D Structure is Not Available
3D MOL 2D MOL
Cross-matching ID
TTD ID
D01BWJ

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 135 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 1.5201 2.1709 1.5201 30.1418
JK1 CTRP2 2.4868 5.911 2.1975 24.703
JM1 CTRP2 1.6288 3.2403 1.6252 29.4294
GA-10 CTRP2 -0.9392 1.3104 -0.9414 46.5304
KMS-26 CTRP2 -0.9192 -0.0537 -0.9192 46.3926
Pfeiffer CTRP2 -0.686 2.0064 -0.6961 44.8632
AML-193 CTRP2 -0.4089 0.1439 -0.4089 42.9925
NU-DHL-1 CTRP2 -0.0798 3.1541 -0.1249 40.9283
EoL-1 CTRP2 -0.0507 1.7909 -0.0519 40.6101
KMS-21-BM CTRP2 0.0155 1.999 0.0132 40.1726
OPM-2 CTRP2 0.042 1.6663 0.0416 39.9903
SUP-T11 CTRP2 0.3253 2.4893 0.3194 38.1205
697 CTRP2 0.3473 2.0611 0.3462 37.9585
KMS-34 CTRP2 0.3543 1.3381 0.3543 37.9079
TALL-1 [Human adult T-ALL] CTRP2 0.3578 2.4137 0.3535 37.8989
DEL CTRP2 0.4881 0.854 0.4881 37.017
SUP-M2 CTRP2 0.5001 2.3539 0.4977 36.9448
KMS-12-BM CTRP2 0.5336 1.5145 0.5336 36.714
ST486 CTRP2 0.5489 3.0586 0.5304 36.6719
RS4;11 CTRP2 0.596 1.7093 0.596 36.2982
Kasumi-2 CTRP2 0.6049 2.0081 0.6047 36.2395
HuT 78 CTRP2 0.6247 1.8602 0.6246 36.1071
SEM CTRP2 0.798 1.506 0.798 34.9522
Mino CTRP2 0.8217 2.7802 0.8166 34.8113
MOLM-13 CTRP2 0.8285 2.3225 0.8279 34.7512
KE-37 CTRP2 0.8895 1.8961 0.8895 34.3429
KMS-11 CTRP2 0.9341 2.837 0.9293 34.0615
OCI-Ly19 CTRP2 0.9444 3.6467 0.9061 34.1028
MOLP-8 CTRP2 0.9444 3.0927 0.9338 34.0122
Mono-Mac-1 CTRP2 1.0211 4.8517 0.8359 34.0614
MOLT-16 CTRP2 1.0632 2.1513 1.0632 33.1855
OCI-AML-3 CTRP2 1.0861 2.4067 1.0858 33.0338
SK-MM-2 CTRP2 1.1191 2.8349 1.1163 32.8223
NALM-6 CTRP2 1.1299 2.4227 1.1296 32.7422
NU-DUL-1 CTRP2 1.1318 2.4314 1.1315 32.7291
NCI-H929 CTRP2 1.1392 2.4472 1.1388 32.6805
EB1 CTRP2 1.1557 2.4055 1.1555 32.5701
KMS-27 CTRP2 1.1606 2.0042 1.1606 32.5363
KHM-1B CTRP2 1.1975 2.1681 1.1975 32.2908
Daudi CTRP2 1.2094 2.4707 1.2091 32.2124
RCH-ACV CTRP2 1.2116 2.1824 1.2116 32.1969
KMS-18 CTRP2 1.246 2.4036 1.2459 31.9681
ALL-SIL CTRP2 1.2521 2.3951 1.2519 31.9276
MOLT-3 CTRP2 1.2793 1.8868 1.2793 31.7457
Ku812 CTRP2 1.2822 3.0991 1.277 31.7439
P12-Ichikawa CTRP2 1.2967 2.0475 1.2967 31.6301
KMS-20 CTRP2 1.3262 2.401 1.3262 31.4333
MOLM-6 CTRP2 1.333 2.6589 1.3325 31.3896
Ri-1 CTRP2 1.3533 3.774 1.3226 31.3551
MOLP-2 CTRP2 1.361 2.7126 1.3604 31.2035
U-937 CTRP2 1.3624 3.2825 1.3542 31.2194
Granta-519 CTRP2 1.3652 3.2343 1.3583 31.1965
EJM CTRP2 1.3673 2.8011 1.3663 31.1626
HPB-ALL CTRP2 1.4005 2.1249 1.4005 30.9384
EM-2 CTRP2 1.4323 2.3599 1.4323 30.7262
CA46 CTRP2 1.4384 2.3982 1.4384 30.6859
L-363 CTRP2 1.4394 3.2614 1.433 30.7005
JVM-3 CTRP2 1.4581 2.3138 1.4581 30.5548
OCI-Ly3 CTRP2 1.4694 2.9047 1.4682 30.483
CML-T1 CTRP2 1.4808 2.1309 1.4808 30.403
HH [Human lymphoma] CTRP2 1.4815 2.5049 1.4815 30.3986
KO52 CTRP2 1.4993 2.1054 1.4993 30.2804
SET-2 CTRP2 1.5159 2.0301 1.5159 30.1694
F-36P CTRP2 1.5176 2.4408 1.5176 30.1583
Peer CTRP2 1.5337 2.3327 1.5337 30.0512
MV4-11 CTRP2 1.5377 2.2812 1.5377 30.0244
Namalwa CTRP2 1.5457 2.1431 1.5457 29.9712
SR CTRP2 1.5996 2.6753 1.5995 29.6123
A3/Kawakami CTRP2 1.6136 2.0207 1.6136 29.5188
LP-1 CTRP2 1.6162 2.3636 1.6162 29.501
SU-DHL-6 CTRP2 1.6193 3.8796 1.5918 29.5725
PF-382 CTRP2 1.6318 2.4536 1.6318 29.3975
WSU-DLCL2 CTRP2 1.6372 2.0352 1.6372 29.3614
SU-DHL-1 CTRP2 1.6522 2.0193 1.6522 29.2612
U266B1 CTRP2 1.6612 2.7121 1.6611 29.202
JURL-MK1 CTRP2 1.6721 3.4394 1.6652 29.1519
L-428 CTRP2 1.7894 2.7132 1.7893 28.3477
SKM-1 CTRP2 1.7949 2.4326 1.7949 28.3108
NCO2 CTRP2 1.8337 2.9383 1.8335 28.0527
HD-MY-Z CTRP2 1.8404 2.4954 1.8404 28.0078
Ki-JK CTRP2 1.8752 3.6641 1.8656 27.8079
DB CTRP2 1.9047 3.1036 1.9042 27.581
MJ CTRP2 1.9429 4.2188 1.9041 27.4548
BV-173 CTRP2 1.9485 3.2729 1.9471 27.2921
A4/Fukuda CTRP2 1.9624 2.8915 1.9623 27.1952
KYO-1 CTRP2 1.9658 3.94 1.9468 27.2359
BL-70 CTRP2 1.9957 2.8517 1.9957 26.9728
SUP-HD1 CTRP2 2.0068 3.7118 1.9983 26.9272
OCI-M1 CTRP2 2.0132 3.7395 2.004 26.8873
MOLM-16 CTRP2 2.0343 4.2534 1.9969 26.8413
TF-1 CTRP2 2.1151 2.8215 2.1151 26.1773
ME1 CTRP2 2.1373 4.5769 2.0734 26.2451
L-540 CTRP2 2.1667 3.505 2.1646 25.8408
DND-41 CTRP2 2.2101 3.3239 2.2096 25.5465
MOTN-1 CTRP2 2.211 3.0797 2.2109 25.5389
Karpas-422 CTRP2 2.2376 3.0972 2.2376 25.3615
MHH-CALL-3 CTRP2 2.2606 5.9047 1.9524 26.2698
SIG-M5 CTRP2 2.2675 2.8433 2.2675 25.1622
KE-97 CTRP2 2.268 2.9242 2.268 25.1588
JeKo-1 CTRP2 2.2871 3.0344 2.2871 25.0317
HL-60 CTRP2 2.3029 2.9572 2.3029 24.9262
RPMI-8402 CTRP2 2.3206 3.0562 2.3206 24.8082
HDLM-2 CTRP2 2.3262 3.9731 2.3158 24.8061
SU-DHL-8 CTRP2 2.3424 5.2443 2.1913 25.1794
SUP-T1 CTRP2 2.3432 3.1707 2.3431 24.6583
Kasumi-1 CTRP2 2.3702 3.1328 2.3701 24.4784
RPMI-8226 CTRP2 2.3773 3.1573 2.3773 24.4305
JJN-3 CTRP2 2.3979 3.1139 2.3979 24.2935
MHH-CALL-4 CTRP2 2.3984 3.7747 2.3947 24.3025
M-07e CTRP2 2.412 2.9834 2.412 24.1992
SUP-B15 CTRP2 2.4189 3.2131 2.4189 24.1537
RL CTRP2 2.4358 2.9392 2.4358 24.0407
MM1.S CTRP2 2.4839 5.8943 2.1987 24.7077
AMO1 CTRP2 2.4889 3.6307 2.4877 23.6912
HT CTRP2 2.4965 2.937 2.4965 23.6367
OCI-AML-5 CTRP2 2.4978 2.942 2.4978 23.628
SU-DHL-4 CTRP2 2.5028 7.7614 1.6047 26.7337
PL21 CTRP2 2.5075 3.396 2.5074 23.5635
HEL 92.1.7 CTRP2 2.5292 2.9026 2.5292 23.419
HEL CTRP2 2.5519 2.9935 2.5519 23.2678
Ci-1 CTRP2 2.558 2.8807 2.558 23.227
SU-DHL-10 CTRP2 2.5711 9.3327 1.0358 28.4082
KCL-22 CTRP2 2.5737 3.2479 2.5737 23.122
MC116 CTRP2 2.5806 3.0321 2.5806 23.0761
Jurkat CTRP2 2.5881 3.0461 2.5881 23.0264
RPMI-6666 CTRP2 2.6069 3.1102 2.6069 22.9009
CMK CTRP2 2.6196 2.9607 2.6196 22.8167
LAMA-84 CTRP2 2.6618 3.3616 2.6618 22.5352
K-562 CTRP2 2.7326 3.5294 2.7325 22.064
Mono-Mac-6 CTRP2 3.0434 17.8944 -2.5359 35.2708
OCI-Ly10 CTRP2 3.7675 7.5853 3.0179 17.9258
Toledo CTRP2 3.8093 6.0702 3.5981 15.6299
Karpas-620 CTRP2 5.0264 7.0227 4.5701 8.4907
P3HR-1 CTRP2 5.0373 10.4146 2.9721 14.9454
REC-1 CTRP2 5.7948 7.1537 5.2701 3.7709
⏷ Show the Full List of 135 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 1.4572 3.5226 1.4431 30.6077
TE15 CTRP2 2.7106 4.4946 2.6843 22.2983
KYSE-140 CTRP2 1.0619 7.6905 0.0826 36.009
TE-5 CTRP2 1.3944 3.5266 1.3784 31.0324
TE-6 CTRP2 2.0632 3.8377 2.0516 26.5621
TE-4 CTRP2 2.2889 3.6909 2.2854 25.0311
OE21 CTRP2 2.4143 3.174 2.4143 24.1841
KYSE-150 CTRP2 2.4402 2.9889 2.4402 24.0117
KYSE-410 CTRP2 2.4568 3.3738 2.4566 23.9019
OE33 CTRP2 2.528 3.3885 2.5279 23.4268
TE-11 CTRP2 2.5316 3.4906 2.5313 23.4039
EC-GI-10 CTRP2 2.5567 3.7351 2.5551 23.2411
KYSE-30 CTRP2 2.5657 3.0823 2.5657 23.1757
KYSE-450 CTRP2 2.5865 3.1009 2.5865 23.0371
TE-1 CTRP2 2.6087 6.4667 2.1716 24.4196
OE19 CTRP2 2.6204 2.9949 2.6204 22.8112
KYSE-180 CTRP2 2.6215 3.3104 2.6215 22.8039
KYSE-520 CTRP2 2.6849 4.0928 2.6782 22.4038
TE-9 CTRP2 2.7426 3.3109 2.7426 21.9972
TE-14 CTRP2 2.7478 3.6498 2.7475 21.9634
TE-10 CTRP2 2.8026 4.2584 2.7927 21.6304
KYSE-510 CTRP2 2.8402 3.5658 2.8402 21.3467
COLO 680N CTRP2 3.4246 5.0388 3.3842 17.5901
KYSE-70 CTRP2 7.8769 15.6738 2.6583 10.8575
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 2.5567 3.0193 2.5567 23.2354
SU.86.86 CTRP2 0.6215 3.5539 0.5764 36.2726
KP-4 CTRP2 1.5268 2.3229 1.5268 30.0969
PSN1 CTRP2 1.5764 2.1404 1.5764 29.7667
DAN-G CTRP2 1.6842 2.1638 1.6842 29.048
MIA PaCa-2 CTRP2 1.9559 2.6581 1.9559 27.2383
Panc 03.27 CTRP2 2.0499 3.0134 2.0498 26.6124
BxPC-3 CTRP2 2.4207 3.4971 2.4201 24.1435
KP-2 CTRP2 2.424 2.9145 2.424 24.1194
HuP-T4 CTRP2 2.5348 3.6513 2.5338 23.3847
PaTu 8988s CTRP2 2.5415 4.111 2.531 23.3719
AsPC-1 CTRP2 2.5442 3.6517 2.5432 23.3222
PK-59 CTRP2 2.567 4.0672 2.5587 23.1947
HuP-T3 CTRP2 2.5869 3.6215 2.5863 23.0362
Capan-1 CTRP2 2.5917 3.576 2.5913 23.0037
Panc 04.03 CTRP2 2.6045 3.1215 2.6045 22.9173
Panc 08.13 CTRP2 2.6087 4.2859 2.592 22.9449
KP-3 CTRP2 2.6463 3.9304 2.6429 22.65
PK-45H CTRP2 2.6501 5.9084 2.3763 23.5633
HPAF-II CTRP2 2.6847 3.94 2.6815 22.3932
Panc 10.05 CTRP2 2.6869 3.7009 2.6863 22.37
Panc 02.03 CTRP2 2.694 3.8898 2.6917 22.3282
PaTu 8988t CTRP2 2.7366 3.1876 2.7366 22.037
QGP-1 CTRP2 2.8758 4.5505 2.8523 21.1882
HPAC CTRP2 2.8871 4.423 2.872 21.0849
SNU-410 CTRP2 2.8963 5.4476 2.7514 21.4703
Capan-2 CTRP2 2.9216 4.7627 2.8823 20.9369
Hs 766T CTRP2 3.6071 4.9511 3.5848 16.3125
PaTu 8902 CTRP2 3.9674 5.2639 3.9335 13.9517
SW1990 CTRP2 3.9763 6.4034 3.6801 14.8306
SUIT-2 CTRP2 4.0831 6.5958 3.7316 14.3268
CFPAC-1 CTRP2 4.9457 22.8352 -3.2833 32.3519
YAPC CTRP2 5.493 8.8328 4.1677 9.0207
SNU-213 CTRP2 5.9064 16.0325 0.9349 20.5504
TCC-Pan2 CTRP2 5.9568 11.3372 3.3247 11.5654
L3.3 CTRP2 6.3608 10.2873 4.1805 7.2425
Panc 05.04 CTRP2 6.8571 18.4364 0.512 20.0313
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 2.2268 5.9953 1.8915 26.5882
WM266-4 CTRP2 1.6416 2.1848 1.6416 29.3322
WM115 CTRP2 1.7167 3.2786 1.7135 28.8424
SK-MEL-1 CTRP2 1.7827 2.3909 1.7827 28.3922
Hs 294T CTRP2 1.7888 3.7465 1.7739 28.4015
WT2-iPS CTRP2 1.8744 4.0139 1.8479 27.8697
COLO 829 CTRP2 1.8823 4.4549 1.8172 27.9475
IGR-1 CTRP2 1.9874 6.4489 1.5001 28.6873
Hs 944.T CTRP2 2.1687 4.7316 2.0875 26.0948
UACC-257 CTRP2 2.317 3.8018 2.3116 24.8506
Hs 934.T CTRP2 2.3271 4.1808 2.3067 24.8335
UACC-62 CTRP2 2.3408 3.2763 2.3407 24.6741
COLO 792 CTRP2 2.3472 3.4755 2.3464 24.6337
SK-MEL-28 CTRP2 2.3831 3.8494 2.3776 24.4106
Malme-3M CTRP2 2.4543 4.5763 2.4085 24.0721
K029AX CTRP2 2.4841 2.9347 2.4841 23.7195
SK-MEL-5 CTRP2 2.4908 2.9872 2.4908 23.6743
LOX-IMVI CTRP2 2.4935 3.0515 2.4935 23.6565
Mel Ho CTRP2 2.4986 3.8794 2.4942 23.6373
A-375 CTRP2 2.5419 4.2013 2.5275 23.3823
CJM [Human melanoma] CTRP2 2.5562 2.9769 2.5562 23.239
HMCB CTRP2 2.6326 3.0383 2.6326 22.7297
Mel JuSo CTRP2 2.6582 4.518 2.6278 22.6616
SK-MEL-24 CTRP2 2.6624 4.8649 2.5959 22.7565
SK-MEL-3 CTRP2 2.7223 4.0418 2.7175 22.1483
A2058 CTRP2 2.7258 3.196 2.7258 22.1091
IGR-39 CTRP2 2.7492 3.3287 2.7492 21.9531
A101D CTRP2 2.7873 3.2491 2.7873 21.6994
IGR-37 CTRP2 2.8588 4.2964 2.8488 21.2563
WM983B CTRP2 3.0055 5.0624 2.9353 20.4839
HT-144 CTRP2 3.1143 5.2107 3.0297 19.8085
RVH-421 CTRP2 3.2012 5.4161 3.0878 19.3301
SK-MEL-31 CTRP2 3.2948 5.3841 3.1947 18.6604
MeWo CTRP2 3.458 5.4534 3.3584 17.572
Hs 852.T CTRP2 3.5141 6.574 3.1221 18.2532
Hs 895.T CTRP2 3.5884 5.4664 3.4968 16.6755
COLO 800 CTRP2 3.8313 6.2623 3.5663 15.6795
Hs 839.T CTRP2 4.0458 5.799 3.9251 13.7321
Hs 688(A).T CTRP2 4.2435 5.7582 4.1491 12.3231
MDA-MB-435S CTRP2 4.3199 8.0395 3.3997 14.9609
SK-MEL-30 CTRP2 4.3215 6.3584 4.0699 12.373
WM1799 CTRP2 4.7238 9.7439 3.0049 15.5384
Hs 936.T CTRP2 4.962 13.3818 1.4387 20.89
SK-MEL-2 CTRP2 5.1809 20.2405 -1.7855 29.1604
WM793 CTRP2 11.1402 23.1032 1.2955 11.1104
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 1.3171 2.9563 1.3145 31.5024
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-BE(2) CTRP2 0.3107 4.5465 0.1231 38.7348
CHP-212 CTRP2 1.8847 3.0894 1.8842 27.7142
CHP-126 CTRP2 2.0451 3.0713 2.045 26.6443
IMR-32 CTRP2 2.0584 2.8983 2.0583 26.5557
SK-N-DZ CTRP2 2.2327 2.9436 2.2327 25.3943
SK-N-AS CTRP2 2.2446 3.3934 2.2438 25.3175
SK-N-SH CTRP2 2.2939 3.6162 2.2915 24.9945
Kelly CTRP2 2.4657 3.041 2.4657 23.8415
NH-6 CTRP2 2.4811 3.0164 2.4811 23.739
NB1 CTRP2 2.5478 2.9754 2.5478 23.2946
KP-N-YN CTRP2 2.5498 7.357 1.806 25.8937
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 CTRP2 1.726 2.7995 1.7259 28.77
SNU-245 CTRP2 1.8673 4.0466 1.8383 27.9258
HuH-28 CTRP2 1.9283 3.268 1.9269 27.4267
SNU-478 CTRP2 2.2434 3.0848 2.2434 25.3227
SNU-869 CTRP2 2.4563 3.9734 2.4487 23.9301
SNU-1079 CTRP2 2.5329 3.7977 2.5304 23.4024
SNU-1196 CTRP2 3.4252 4.3434 3.4236 17.4545
SNU-308 CTRP2 3.7646 5.0741 3.7391 15.2742
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U2OS CTRP2 0.742 3.3291 0.7162 35.4096
SK-ES-1 CTRP2 1.4585 2.058 1.4585 30.5518
SJSA-1 CTRP2 1.4915 2.4967 1.4914 30.3323
CAL-78 CTRP2 1.6749 2.8991 1.6745 29.1115
SaOS-2 CTRP2 1.6785 2.7268 1.6784 29.0864
A-673 CTRP2 1.8848 2.7899 1.8848 27.7118
HOS CTRP2 1.9429 2.8624 1.9428 27.3252
MG-63 CTRP2 2.1101 4.7676 2.02 26.5154
SW1353 CTRP2 2.1395 4.131 2.1155 26.0955
SK-N-MC CTRP2 2.2409 2.827 2.2409 25.3394
MHH-ES-1 CTRP2 2.3976 3.1368 2.3976 24.2957
Hs 888.T CTRP2 2.4077 5.7521 2.1514 25.1124
TC71 CTRP2 2.5658 2.9332 2.5658 23.1747
G-292 clone A141B1 CTRP2 3.3196 5.7757 3.1396 18.7765
Hs 822.T CTRP2 4.7634 5.1256 4.7633 8.5343
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 72 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-157 CTRP2 0.915 3.4109 0.8904 34.2538
HCC1569 CTRP2 1.0626 4.7778 0.8937 33.7363
DU4475 CTRP2 1.2501 2.5635 1.2497 31.9418
Hs 578T CTRP2 1.5032 4.9755 1.334 30.8186
HCC1954 CTRP2 1.5455 2.4472 1.5454 29.9726
HCC1500 CTRP2 1.6284 2.2582 1.6284 29.4197
MDA-MB-453 CTRP2 1.6357 2.2795 1.6357 29.3717
AU565 CTRP2 2.1997 6.4563 1.7293 27.2353
HDQ-P1 CTRP2 2.3004 3.5831 2.2985 24.9494
Hs 578Bst CTRP2 2.3089 3.9435 2.2992 24.9188
HCC1428 CTRP2 2.3445 4.1476 2.3266 24.7091
HCC1143 CTRP2 2.3647 5.9403 2.0566 25.579
HMC-1-8 CTRP2 2.4052 2.8293 2.4052 24.2448
HCC2218 CTRP2 2.4523 3.6432 2.4508 23.9361
HCC1806 CTRP2 2.4761 3.016 2.4761 23.7723
MDA-MB-361 CTRP2 2.4842 3.8696 2.4797 23.7336
ZR-75-30 CTRP2 2.5373 3.8653 2.5336 23.377
BT-20 CTRP2 2.538 4.3652 2.5138 23.4415
HCC38 CTRP2 2.5428 3.5409 2.5424 23.3294
CAL-51 CTRP2 2.5522 3.8506 2.549 23.2761
BT-549 CTRP2 2.5702 4.0568 2.5623 23.172
KPL-1 CTRP2 2.6639 3.669 2.6634 22.523
HCC202 CTRP2 2.727 4.1273 2.72 22.1245
CAL-148 CTRP2 2.7544 3.6146 2.7542 21.919
HCC1395 CTRP2 2.882 4.3129 2.8719 21.1023
JIMT-1 CTRP2 2.9295 3.8805 2.9288 20.7544
T-47D CTRP2 2.9334 4.3361 2.9237 20.7586
CAL-85-1 CTRP2 3.0217 5.3088 2.9134 20.5078
MDA-MB-468 CTRP2 3.2082 5.5856 3.0613 19.4008
MDA-MB-231 CTRP2 3.4017 7.5998 2.625 20.4349
MCF-7 CTRP2 3.5336 15.5208 -0.9202 31.0083
BT-474 CTRP2 3.5506 4.7324 3.5403 16.6485
HCC1937 CTRP2 3.5536 5.5821 3.4369 16.995
SK-BR-3 CTRP2 3.6612 5.6974 3.5294 16.3318
HCC1419 CTRP2 4.3251 6.7777 3.927 12.8978
CAL-120 CTRP2 4.767 6.8966 4.3514 10.0419
ZR-75-1 CTRP2 5.3628 8.9536 3.9889 10.0507
CAMA-1 CTRP2 7.7077 9.7223 5.337 0.9224
BT 498 CTRP2 0.1974 5.8741 -0.2909 40.1678
BT 172 CTRP2 0.9296 3.0281 0.9206 34.1053
BT 428 CTRP2 1.2058 2.4916 1.2055 32.2363
BT 248 CTRP2 1.3006 2.4041 1.3006 31.6039
BT 416 CTRP2 1.3218 2.0921 1.3218 31.4628
BT147 CTRP2 1.3727 3.0707 1.3691 31.1355
BT 245 CTRP2 1.5663 2.619 1.5662 29.8342
BT 239 CTRP2 1.5709 2.0768 1.5709 29.8032
BT 286 CTRP2 1.5818 2.2066 1.5818 29.7305
BT 422 CTRP2 1.5821 3.9854 1.5457 29.8501
BT 271 CTRP2 1.7113 2.2843 1.7113 28.8676
BT 440 CTRP2 1.7434 2.4837 1.7434 28.6539
BT 145 CTRP2 1.7802 2.8603 1.7801 28.4091
BT 333 CTRP2 1.8221 2.806 1.8221 28.1295
BT 216 CTRP2 1.8227 3.1269 1.8217 28.129
BT 504 CTRP2 1.8373 2.7584 1.8373 28.0282
BT 131 CTRP2 1.8926 2.5324 1.8926 27.6597
BT 330 CTRP2 1.9513 2.7728 1.9513 27.2688
BT 328 CTRP2 2.0294 2.8412 2.0293 26.7489
BT 232 CTRP2 2.0831 3.0399 2.083 26.3908
BT 340 CTRP2 2.1429 2.906 2.1429 25.9923
BT 444 CTRP2 2.1612 2.9479 2.1611 25.8708
BT 482 CTRP2 2.1663 4.054 2.1477 25.8987
BT164 CTRP2 2.2015 3.2394 2.2012 25.603
BT 112 CTRP2 2.2114 3.2577 2.2111 25.5367
BT 359 CTRP2 2.2637 3.2168 2.2635 25.1882
BT 228 CTRP2 2.3027 3.4709 2.3018 24.9308
BT 231 CTRP2 2.3372 3.4998 2.3362 24.7012
BT 179 CTRP2 2.4251 4.1714 2.4086 24.1674
BT 159 CTRP2 2.4601 3.6443 2.4587 23.8838
BT 139 CTRP2 2.5885 3.3715 2.5884 23.0239
BT 187 CTRP2 2.6398 3.4912 2.6397 22.6824
BT 224 CTRP2 2.678 3.1698 2.678 22.4277
BT 320 CTRP2 3.419 4.1089 3.4188 17.4916
⏷ Show the Full List of 72 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 2.6045 2.9378 2.6045 22.9173
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KNS-60 CTRP2 0.3717 2.3851 0.3679 37.8049
Daoy CTRP2 0.7239 2.2322 0.7233 35.4482
SF539 CTRP2 0.8815 1.9575 0.8815 34.3957
SNU-466 CTRP2 1.3455 2.0815 1.3455 31.3048
SF268 CTRP2 1.6133 3.38 1.6068 29.5425
GB-1 CTRP2 1.6883 3.4428 1.6815 29.0436
U-118MG CTRP2 1.7906 3.1722 1.7891 28.3444
U-251MG CTRP2 2.0451 3.3116 2.044 26.6474
SF126 CTRP2 2.4415 4.0276 2.4317 24.0358
LN-229 CTRP2 2.4446 3.1142 2.4446 23.9821
KNS-81 CTRP2 2.4549 5.6145 2.2356 24.6687
D283 Med CTRP2 2.458 4.2531 2.438 23.96
SNB-75 CTRP2 2.4623 3.8183 2.4586 23.8767
M059K CTRP2 2.5005 2.9379 2.5005 23.6098
SNU-1105 CTRP2 2.505 2.9476 2.505 23.58
LN-18 CTRP2 2.5164 2.915 2.5164 23.5042
ONS-76 CTRP2 2.5279 2.9555 2.5279 23.4272
DK-MG CTRP2 2.539 3.0705 2.539 23.3533
KALS-1 CTRP2 2.5536 5.2939 2.4104 23.7461
YH-13 CTRP2 2.5715 3.0675 2.5715 23.1369
CAS-1 CTRP2 2.6147 4.4526 2.5875 22.9404
Hs 683 CTRP2 2.6348 3.1005 2.6348 22.7154
42-MG-BA CTRP2 2.6386 3.2491 2.6386 22.6899
GMS-10 CTRP2 2.6685 4.0533 2.6626 22.5103
SW1088 CTRP2 2.6828 4.1697 2.6735 22.4265
TM-31 CTRP2 2.7183 4.2557 2.7063 22.1993
A-172 CTRP2 2.736 6.3567 2.344 23.4153
CCF-STTG1 CTRP2 2.7717 4.3507 2.7567 21.8533
SNU-738 CTRP2 2.8812 5.2025 2.7803 21.4176
SF295 CTRP2 2.8925 4.1408 2.8881 21.0132
DBTRG-05MG CTRP2 3.083 4.2003 3.08 19.7393
U-87MG ATCC CTRP2 3.3396 6.8005 2.8563 19.7484
GaMG CTRP2 3.4433 5.476 3.3383 17.6883
GOS-3 CTRP2 3.5294 5.7663 3.3703 17.3057
YKG-1 CTRP2 3.5403 5.6899 3.3996 17.1683
T98G CTRP2 3.6778 8.2709 2.6377 19.6252
8-MG-BA CTRP2 3.807 6.4347 3.4859 16.0471
KG-1-C CTRP2 3.8331 6.1428 3.6035 15.5385
KNS-42 CTRP2 3.893 5.7714 3.765 14.7753
Becker CTRP2 3.9291 5.689 3.8223 14.4601
SNU-201 CTRP2 4.4181 5.661 4.3576 11.0413
NMC-G1 CTRP2 4.6338 6.1359 4.479 9.9424
SW1783 CTRP2 4.8825 7.4834 4.2205 10.2503
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-265 CTRP2 -0.4941 8.786 -1.9909 45.4338
HEC-251 CTRP2 1.6147 5.8587 1.2596 30.6946
HEC-151 CTRP2 1.6885 2.8622 1.6882 29.0206
JHUEM-1 CTRP2 1.7083 2.2089 1.7083 28.8878
KLE CTRP2 1.799 3.3385 1.7957 28.2945
HEC-1-A CTRP2 1.8198 3.2658 1.8177 28.1517
AN3-CA CTRP2 1.8649 2.8554 1.8649 27.8444
MFE-296 CTRP2 2.1961 3.8781 2.1861 25.6714
JHUEM-7 CTRP2 2.2752 3.5305 2.2737 25.1161
ESS-1 CTRP2 2.317 4.4547 2.2757 24.9711
JHUEM-2 CTRP2 2.4359 3.302 2.4358 24.0406
MFE-319 CTRP2 2.4707 3.0547 2.4707 23.8087
JHUEM-3 CTRP2 2.5228 4.7951 2.4563 23.6865
RL95-2 CTRP2 2.5392 3.0579 2.5392 23.3521
HEC-108 CTRP2 2.5554 2.9484 2.5554 23.244
EN CTRP2 2.6595 3.1839 2.6595 22.5507
HEC-59 CTRP2 2.7306 3.7769 2.7297 22.0801
HEC-50B CTRP2 2.8263 6.2105 2.4856 22.6322
EFE-184 CTRP2 3.5135 8.1955 2.4989 20.5987
HEC-1-B CTRP2 4.528 7.9642 3.6453 13.4504
Ishikawa (Heraklio) 02 ER- CTRP2 2.607 3.0916 2.607 22.9005
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UO-31 CTRP2 0.5894 2.1913 0.5885 36.345
TUHR4TKB CTRP2 1.9456 2.9355 1.9455 27.307
TUHR10TKB CTRP2 2.2941 4.4558 2.2516 25.128
BFTC-909 CTRP2 2.3611 5.272 2.2062 25.0681
KMRC-1 CTRP2 2.3784 3.6623 2.3762 24.431
TUHR14TKB CTRP2 2.4298 4.8472 2.3504 24.35
CAL-54 CTRP2 2.5278 3.3377 2.5278 23.4281
786-O CTRP2 2.5632 3.2844 2.5632 23.192
ACHN CTRP2 2.6171 3.9502 2.6128 22.8475
OS-RC-2 CTRP2 2.6999 5.2998 2.5675 22.7344
VMRC-RCW CTRP2 2.8219 4.2665 2.8122 21.5011
A-498 CTRP2 2.8308 4.2245 2.8228 21.4361
769-P CTRP2 2.8368 5.3078 2.7139 21.7898
RCC10RGB CTRP2 2.9959 4.3834 2.9859 20.343
SNU-1272 CTRP2 3.0095 4.1477 3.0065 20.2289
KMRC-20 CTRP2 3.0643 4.597 3.0451 19.918
KMRC-3 CTRP2 3.2871 6.5121 2.8958 19.7573
VMRC-RCZ CTRP2 3.6992 6.0392 3.4865 16.3678
KMRC-2 CTRP2 3.8707 5.9961 3.6852 15.1288
Caki-2 CTRP2 4.0567 7.4669 3.3708 15.775
Caki-1 CTRP2 4.1706 7.465 3.4912 14.9993
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LS123 CTRP2 1.3976 2.3541 1.3976 30.9574
SW948 CTRP2 1.5149 3.6698 1.4958 63.857
SW48 CTRP2 1.5859 2.6231 1.5858 29.7034
DLD-1 CTRP2 1.6066 2.0034 1.6066 29.565
COLO 320 CTRP2 1.6143 2.8274 1.6139 29.5153
NCI-H747 CTRP2 1.6614 2.6894 1.6613 29.2007
SNU-C5 CTRP2 1.6666 2.967 1.6659 29.1679
SNU-407 CTRP2 1.9258 3.5651 1.9198 27.4587
SNU-C2A CTRP2 2.0601 4.1677 2.0304 26.6434
LS513 CTRP2 2.1236 2.8129 2.1236 26.1212
T84 CTRP2 2.1251 3.5712 2.1217 26.1223
GP2d CTRP2 2.2816 3.9678 2.2703 25.1062
LoVo CTRP2 2.2946 4.7068 2.2248 25.2177
CL-11 CTRP2 2.3032 4.3309 2.2718 25.0299
CW-2 CTRP2 2.3506 4.5186 2.305 24.7622
COLO 678 CTRP2 2.3748 3.9253 2.367 24.4735
SW1417 CTRP2 2.3753 3.2513 2.3752 24.4441
RKO CTRP2 2.405 4.3564 2.376 24.3438
SNU-61 CTRP2 2.4123 3.7237 2.4096 24.2065
SNU-503 CTRP2 2.4658 4.5808 2.4201 23.9951
HT115 CTRP2 2.4679 3.0281 2.4679 23.8269
HCC-56 CTRP2 2.4772 2.9547 2.4772 23.7652
SNU-1033 CTRP2 2.4886 3.4736 2.4883 23.6902
LS1034 CTRP2 2.4925 3.2317 2.4925 23.6631
COLO205 CTRP2 2.4955 3.0815 2.4955 23.6432
HCT 15 CTRP2 2.5514 3.6519 2.5504 23.2743
HT-55 CTRP2 2.5532 3.0502 2.5532 23.259
MDST8 CTRP2 2.5609 3.1695 2.5609 23.2076
NCI-H716 CTRP2 2.6281 3.6209 2.6276 22.7615
SK-CO-1 CTRP2 2.6565 3.3052 2.6565 22.5705
LS180 CTRP2 2.6607 3.8907 2.658 22.5517
LS411N CTRP2 2.7483 3.3528 2.7483 21.9588
RCM-1 [Human ESC] CTRP2 2.825 4.4257 2.8077 21.5061
SNU-C4 CTRP2 2.8775 4.3197 2.8671 21.1331
C2BBe1 CTRP2 2.9665 6.4679 2.5608 21.9366
HT-29 CTRP2 3.1095 4.7143 3.0837 19.6396
NCI-H508 CTRP2 3.1109 4.8328 3.0747 19.6655
KM12 CTRP2 3.1641 5.2168 3.0822 19.4674
HCT 116 CTRP2 3.2982 4.9449 3.2608 18.4217
HCT 8 CTRP2 3.349 4.9851 3.3101 18.0882
SW620 CTRP2 3.6639 6.1645 3.4128 16.7416
OUMS-23 CTRP2 3.9423 5.9583 3.7732 14.5935
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-182 CTRP2 0.5687 2.7704 0.5603 36.5073
SNU-761 CTRP2 0.7604 3.559 0.7208 35.3317
HuH-6 CTRP2 1.4623 3.1484 1.4584 30.5394
JHH-2 CTRP2 1.5582 2.6882 1.558 29.8885
SNU-878 CTRP2 1.7436 2.7578 1.7435 28.6528
JHH-5 CTRP2 2.2664 3.2176 2.2663 25.1697
Li-7 CTRP2 2.3191 4.4446 2.2788 24.9542
JHH-4 CTRP2 2.3721 3.0522 2.3721 24.4651
SNU-449 CTRP2 2.463 3.8707 2.4582 23.8757
SNU-398 CTRP2 2.5159 4.0878 2.5057 23.5414
SNU-423 CTRP2 2.5617 3.2893 2.5617 23.2023
SNU-475 CTRP2 2.6731 3.1644 2.6731 22.4602
PLC/PRF/5 CTRP2 2.7123 4.6467 2.6732 22.3303
Hep 3B2.1-7 CTRP2 2.718 3.4305 2.718 22.161
HLF CTRP2 2.731 4.5513 2.7012 22.1745
JHH-1 CTRP2 2.7806 3.2829 2.7806 21.7441
SNU-387 CTRP2 2.795 5.2753 2.6747 22.0593
SNU-886 CTRP2 3.6234 8.5672 2.4535 23.5581
SK-HEP-1 CTRP2 3.9343 5.7397 3.817 14.4625
JHH-6 CTRP2 4.0513 5.7136 3.9498 13.6277
HuH-1 CTRP2 4.3421 5.4699 4.3061 11.4629
Hep-G2 CTRP2 6.6901 10.9983 4.0829 7.0752
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 136 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2444 CTRP2 -0.383 5.8176 -0.9093 43.7778
NCI-H211 CTRP2 0.3808 1.3139 0.3808 37.7316
NCI-H2087 CTRP2 0.4315 1.843 0.4313 37.3944
NCI-H2141 CTRP2 0.5334 3.5638 0.4836 36.8731
NCI-H1581 CTRP2 0.5742 1.7371 0.5742 36.4432
NCI-H1385 CTRP2 0.6428 2.1146 0.6424 35.9873
NCI-H1666 CTRP2 0.6445 2.9223 0.6332 36.012
NCI-H2081 CTRP2 0.7574 3.3998 0.7281 35.3185
NCI-H2106 CTRP2 0.764 2.0828 0.7638 35.1793
CAL-12T CTRP2 0.8803 22.7599 -6.9289 44.4083
NCI-H1155 CTRP2 0.8887 1.7783 0.8887 34.3483
NCI-H1694 CTRP2 0.9163 1.8753 0.9163 34.1641
Lu-65 CTRP2 0.9636 3.4957 0.9359 33.9404
NCI-H446 CTRP2 1.0784 2.1115 1.0784 33.0841
NCI-H1184 CTRP2 1.1928 3.6994 1.1608 32.4282
DMS 53 CTRP2 1.3309 3.0094 1.3277 31.4125
DV-90 CTRP2 1.3504 2.9079 1.3485 31.2784
NCI-H358 CTRP2 1.3612 3.5423 1.3436 31.259
COR-L279 CTRP2 1.3676 3.0766 1.3638 31.1702
Lu-99 CTRP2 1.4029 2.4246 1.4028 30.9227
COR-L51 CTRP2 1.407 2.7955 1.4062 30.8975
COR-L47 CTRP2 1.4132 5.4174 1.1466 31.7332
DMS 454 CTRP2 1.416 3.603 1.3971 30.898
Sq-1 CTRP2 1.4338 3.7741 1.4061 30.809
NCI-H1105 CTRP2 1.4362 2.4742 1.4361 30.7009
NCI-H146 CTRP2 1.439 2.3824 1.439 30.6819
HCC1588 CTRP2 1.4553 33.5241 -11.6851 45.1275
LCLC-97TM1 CTRP2 1.4563 3.0672 1.4535 30.5756
COLO 699 CTRP2 1.4816 3.9342 1.4447 30.5214
NCI-H810 CTRP2 1.4819 2.5987 1.4818 30.3965
NCI-H23 CTRP2 1.5196 4.15 1.4661 30.3236
NCI-H1650 CTRP2 1.5396 2.8485 1.539 30.0133
NCI-H1793 CTRP2 1.5714 3.3758 1.5644 29.823
EPLC-272H CTRP2 1.586 4.2193 1.5293 29.8923
NCI-H1838 CTRP2 1.5902 2.947 1.5893 29.6772
NCI-H841 CTRP2 1.6101 2.9047 1.6094 29.5442
NCI-H1693 CTRP2 1.6811 2.4423 1.6811 29.0691
NCI-H1341 CTRP2 1.711 2.7914 1.7108 28.8704
NCI-H292 CTRP2 1.7113 3.1415 1.7096 28.8735
Calu-3 CTRP2 1.7267 2.7471 1.7266 28.7655
NCI-H1563 CTRP2 1.7417 3.2587 1.7389 28.6745
NCI-H2171 CTRP2 1.7737 3.3179 1.7705 28.4629
HCC2935 CTRP2 1.783 2.9499 1.7826 28.3913
NCI-H889 CTRP2 1.7881 3.0124 1.7876 28.3579
HOP-62 CTRP2 1.8336 2.9331 1.8334 28.0535
NCI-H226 CTRP2 1.8443 3.7121 1.8323 28.0218
HCC4006 CTRP2 1.8531 3.1802 1.8519 27.9268
HCC1438 CTRP2 1.8556 4.178 1.8162 28.0383
SW1271 CTRP2 1.8664 4.1183 1.8322 27.9489
NCI-H2085 CTRP2 1.8874 4.2162 1.8462 27.8327
ChaGo-K-1 CTRP2 1.91 3.8915 1.8917 27.6052
NCI-H1915 CTRP2 1.9407 3.1053 1.9403 27.3407
COLO 668 CTRP2 1.943 3.366 1.9407 27.3319
NCI-H2029 CTRP2 1.9616 3.0335 1.9614 27.2009
HCC2279 CTRP2 1.9714 3.8729 1.9559 27.1865
SBC-5 CTRP2 2.0205 2.8647 2.0205 26.808
RERF-LC-A1 CTRP2 2.021 4.1313 1.9923 26.9006
NCI-H1869 CTRP2 2.0323 3.0567 2.0322 26.7294
HARA [Human squamous cell lung carcinoma] CTRP2 2.0356 3.12 2.0353 26.7082
Calu-1 CTRP2 2.0629 3.8324 2.0515 26.5637
DMS 273 CTRP2 2.0911 2.9889 2.0911 26.3374
DMS 79 CTRP2 2.1095 3.1532 2.1093 26.2155
NCI-H522 CTRP2 2.1291 3.6801 2.1236 26.1029
HOP-92 CTRP2 2.1354 5.8051 1.8413 27.0507
NCI-H196 CTRP2 2.1426 3.6932 2.137 26.013
HCC1171 CTRP2 2.209 4.8496 2.1141 25.8736
NCI-H1568 CTRP2 2.2229 4.2476 2.1942 25.5556
HCC44 CTRP2 2.2683 3.9934 2.2556 25.1993
NCI-H1573 CTRP2 2.2857 3.4181 2.285 25.0432
NCI-H1703 CTRP2 2.3443 3.2886 2.3441 24.6514
NCI-H2196 CTRP2 2.3485 3.5769 2.347 24.6277
COR-L95 CTRP2 2.3544 3.0015 2.3544 24.5833
HCC1833 CTRP2 2.3722 3.5846 2.3708 24.4695
NCI-H650 CTRP2 2.4194 4.3192 2.3936 24.2368
NCI-H2228 CTRP2 2.4264 3.8653 2.4212 24.1211
VMRC-LCD CTRP2 2.4271 3.6036 2.4258 24.1032
NCI-H661 CTRP2 2.4523 4.8868 2.3689 24.214
Calu-6 CTRP2 2.4568 7.9433 1.4856 27.278
NCI-H1395 CTRP2 2.4944 3.9956 2.4869 23.6758
SHP-77 CTRP2 2.4961 2.9946 2.4961 23.6395
NCI-H2009 CTRP2 2.5076 4.1835 2.4929 23.6119
HCC827 CTRP2 2.5085 4.1089 2.4972 23.5943
RERF-LC-Ad2 CTRP2 2.513 3.0665 2.513 23.5266
NCI-H2110 CTRP2 2.517 3.6564 2.5159 23.5037
NCI-H69 CTRP2 2.5231 3.3447 2.523 23.4596
PC-14 CTRP2 2.5344 3.9309 2.5294 23.4007
DMS 114 CTRP2 2.5457 3.0905 2.5457 23.3091
HCC78 CTRP2 2.554 6.1383 2.2092 24.4535
SK-MES-1 CTRP2 2.5564 3.2731 2.5564 23.2375
LOU-NH91 CTRP2 2.5583 4.4303 2.5302 23.3193
NCI-H838 CTRP2 2.5637 3.0396 2.5637 23.1888
NCI-H526 CTRP2 2.5697 3.1434 2.5697 23.1488
NCI-H727 CTRP2 2.5797 3.2842 2.5797 23.0825
LK2 CTRP2 2.5833 2.8644 2.5833 23.0581
EBC-1 CTRP2 2.5967 3.8816 2.5935 22.9798
NCI-H520 CTRP2 2.6248 3.7526 2.6235 22.7864
NCI-H1944 CTRP2 2.6285 4.4476 2.6022 22.8455
HCC2108 CTRP2 2.6331 4.3131 2.6156 22.7853
LUDLU-1 CTRP2 2.6353 3.2884 2.6353 22.7121
NCI-H1339 CTRP2 2.6799 3.1553 2.6799 22.4147
RERF-LC-MS CTRP2 2.6827 3.6926 2.6821 22.3981
NCI-H322 CTRP2 2.7311 3.195 2.7311 22.0733
HCC1195 CTRP2 2.7644 4.689 2.724 21.988
HCC366 CTRP2 2.7983 4.2612 2.7883 21.6594
RERF-LC-Ad1 CTRP2 2.8148 3.5327 2.8148 21.5161
KNS-62 CTRP2 2.8175 3.7191 2.8172 21.4993
HCC15 CTRP2 2.8907 4.5099 2.8706 21.0779
NCI-H1355 CTRP2 2.8941 5.0121 2.8234 21.2274
NCI-H1435 CTRP2 3.0041 6.5574 2.5734 21.7781
NCI-H2291 CTRP2 3.0152 4.89 2.9676 20.3417
COR-L105 CTRP2 3.0685 5.4242 2.9426 20.2573
NCI-H647 CTRP2 3.1455 5.1409 3.0738 19.5562
HCC95 CTRP2 3.1638 4.0914 3.1629 19.1942
NCI-H1651 CTRP2 3.1778 4.6505 3.1595 19.159
MOR/CPR CTRP2 3.2733 4.3181 3.2705 18.4707
NCI-H2030 CTRP2 3.3077 5.5457 3.1776 18.6795
T3M-10 CTRP2 3.3128 5.1897 3.2457 18.4261
NCI-H2170 CTRP2 3.4934 4.9216 3.4683 17.0796
SK-LU-1 CTRP2 3.6193 7.3135 2.9685 18.5264
NCI-H1623 CTRP2 3.6723 6.8549 3.1965 17.5163
EKVX CTRP2 3.8233 7.0808 3.2754 16.7882
A-549 CTRP2 3.8283 6.0987 3.6109 15.5262
LXF 289 CTRP2 3.8727 6.933 3.3837 16.2384
NCI-H2342 CTRP2 3.9662 6.5812 3.6101 15.1197
NCI-H1373 CTRP2 4.2477 5.7514 4.1551 12.2888
NCI-H460 CTRP2 4.2694 6.3503 4.0159 12.7261
NCI-H2122 CTRP2 4.3983 5.2736 4.3857 11.009
NCI-H1792 CTRP2 4.4641 6.1518 4.2893 11.1433
NCI-H1299 CTRP2 4.4822 9.5293 2.8749 16.6357
NCI-H2126 CTRP2 4.7945 9.7158 3.0856 15.0481
NCI-H2023 CTRP2 6.6345 13.0419 3.0244 11.5081
LCLC-103H CTRP2 7.8568 9.7797 5.3843 0.6923
LC-1/sq-SF CTRP2 7.871 9.5221 5.4912 0.4222
NCI-H2405 CTRP2 8.0964 10.6573 5.1404 1.2321
BEN CTRP2 8.6587 40.7254 -9.1685 33.6476
Hs 888.Lu CTRP2 2.5954 3.2159 2.5954 22.978
⏷ Show the Full List of 136 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 2.272 4.0672 2.256 25.1859
OC 314 CTRP2 0.5653 1.0279 0.5653 36.5023
SNU-119 CTRP2 0.6008 2.1314 0.6002 36.268
OVISE CTRP2 0.8506 2.05 0.8505 34.6019
A2780 CTRP2 0.8526 2.5817 0.8505 34.5954
OVCAR-5 CTRP2 1.089 3.1678 1.079 33.0468
OV7 CTRP2 1.4245 2.8693 1.4233 30.7825
COV644 CTRP2 1.7524 4.554 1.6672 28.8806
TOV-21G CTRP2 1.7592 2.3967 1.7592 28.5483
OAW42 CTRP2 1.891 2.5461 1.891 27.6704
ES2 CTRP2 1.9325 2.5853 1.9325 27.3942
SNU-840 CTRP2 2.0377 4.2914 1.9972 26.8292
TYK-nu CTRP2 2.1047 3.9075 2.0913 26.2915
OAW28 CTRP2 2.1255 4.9395 2.0107 26.4975
ONCO-DG-1 CTRP2 2.1824 3.1169 2.1823 25.7292
OVTOKO CTRP2 2.2112 4.007 2.1963 25.5869
DOV13 CTRP2 2.255 3.1515 2.2549 25.2456
SNU-8 CTRP2 2.3264 2.8506 2.3264 24.7698
TOV-112D CTRP2 2.4332 3.916 2.4268 24.0798
OVK18 CTRP2 2.4383 3.0322 2.4383 24.0244
RMG-I CTRP2 2.4418 6.0939 2.0991 25.1898
IGROV-1 CTRP2 2.4497 3.906 2.4438 23.9681
COV434 CTRP2 2.5115 3.819 2.5084 23.547
OVCAR-4 CTRP2 2.5632 3.7933 2.5609 23.1999
MCAS CTRP2 2.6181 4.3527 2.5977 22.8948
JHOM-1 CTRP2 2.6421 3.1442 2.6421 22.6665
Kuramochi CTRP2 2.7 3.8164 2.6986 22.2855
EFO-21 CTRP2 2.7914 4.2653 2.781 21.7068
EFO-27 CTRP2 3.0074 5.1377 2.9263 20.5088
FU-OV-1 CTRP2 3.0368 6.9159 2.4887 21.9906
HEY A8 CTRP2 3.0765 4.9541 3.0251 19.9462
OV-90 CTRP2 3.4334 4.6497 3.4236 17.4279
JHOS-2 CTRP2 3.674 6.4918 3.3228 17.0409
OV56 CTRP2 3.9203 5.1937 3.8913 14.2489
COV362 CTRP2 5.1811 6.175 5.0636 6.1684
JHOC-5 CTRP2 5.2416 8.4986 4.0975 9.8767
OVCAR-8 CTRP2 5.4002 9.5007 3.7538 10.9427
Caov-3 CTRP2 5.4786 10.8867 3.1369 13.3128
OVSAHO CTRP2 5.5116 10.5569 3.33 12.4534
SK-OV-3 CTRP2 7.1156 13.9398 2.95 10.9638
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 2.3477 3.3428 2.3474 24.6288
H-STS CTRP2 2.488 2.9052 2.488 23.693
SYO-1 CTRP2 2.9669 3.8274 2.9666 20.5037
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 2.5925 3.1072 2.5925 22.9967
Aska-SS CTRP2 2.7709 3.4109 2.7709 21.8085
A-204 CTRP2 0.8362 2.5856 0.8339 34.7057
GCT CTRP2 0.87 2.4644 0.8688 34.4765
RD CTRP2 1.2196 4.5628 1.097 32.5478
KYM-1 CTRP2 1.3215 2.8994 1.3195 31.4715
Rh18 CTRP2 1.3296 2.5885 1.3293 31.4116
Rh41 CTRP2 1.4581 2.5227 1.458 30.5547
HT-1080 CTRP2 1.5783 2.0595 1.5783 29.754
TE 441.T CTRP2 1.5957 2.111 1.5957 29.6376
G-402 CTRP2 1.7579 3.3568 1.7539 28.5705
MES-SA CTRP2 1.7816 2.3229 1.7816 28.3991
TTC-709 CTRP2 1.8734 2.6131 1.8734 27.7875
RKN CTRP2 2.0355 5.3742 1.8324 27.3997
G-401 CTRP2 2.2869 3.7995 2.281 25.0528
SK-UT-1 CTRP2 2.3407 5.8031 2.0657 25.6226
TE 617.T CTRP2 2.3804 3.2895 2.3803 24.4106
SK-LMS-1 CTRP2 2.4532 4.402 2.4228 24.027
Tm87-16 CTRP2 2.4566 3.0319 2.4566 23.9027
Hs 729.T CTRP2 2.5557 3.319 2.5557 23.2423
BT-12 CTRP2 2.6462 2.9105 2.6462 22.6396
SW982 CTRP2 2.7213 4.6764 2.6798 22.2787
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.3066 7.536 3.6038 14.1945
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2452 CTRP2 1.416 3.8945 1.3794 30.9572
NCI-H28 CTRP2 1.5642 3.2083 1.5605 29.86
MSTO-211H CTRP2 1.7048 3.6887 1.6901 28.9603
IST-Mes1 CTRP2 2.5405 3.3949 2.5404 23.3435
JL-1 CTRP2 2.5472 3.0868 2.5472 23.2988
NCI-H2052 CTRP2 3.2909 6.4162 2.9303 19.6196
ACC-MESO-1 CTRP2 3.6907 5.2901 3.6354 15.8683
MPP 89 CTRP2 4.5559 6.2275 4.3665 10.5867
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 CTRP2 1.883 3.5409 1.877 27.7438
DU145 CTRP2 2.4718 4.4872 2.4352 23.9243
VCaP CTRP2 2.5765 4.5613 2.5385 23.2315
LNCaP clone FGC CTRP2 2.6368 3.6158 2.6363 22.7035
PaCa-3 CTRP2 2.701 4.2286 2.6897 22.312
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 1.7816 2.5427 1.7816 28.3996
YD-15 CTRP2 2.6781 4.0775 2.6716 22.4485
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 CTRP2 0.7875 2.4086 0.7863 35.0263
HGC-27 CTRP2 0.8098 2.3037 0.8092 34.8754
MKN1 CTRP2 1.4116 3.5414 1.3955 30.918
Hs 746.T CTRP2 1.4874 1.9905 1.4874 30.3594
SNU-16 CTRP2 1.6265 2.147 1.6265 29.4328
NUGC-4 CTRP2 1.9243 3.8881 1.9066 27.5079
23132/87 CTRP2 2.2399 3.4856 2.2385 25.3507
SNU-1 CTRP2 2.3542 3.6571 2.3519 24.5924
KE-39 CTRP2 2.3782 4.5423 2.3317 24.5811
MKN7 CTRP2 2.4731 3.8193 2.4695 23.8047
Fu97 CTRP2 2.4827 3.4694 2.4824 23.7298
IM95 CTRP2 2.5349 4.1565 2.5223 23.423
HuG1-N CTRP2 2.5424 3.344 2.5424 23.3309
MKN74 CTRP2 2.5763 3.9733 2.5709 23.1227
SNU-668 CTRP2 2.5812 2.89 2.5812 23.0721
GSS CTRP2 2.5936 3.1539 2.5936 22.9897
SNU-5 CTRP2 2.5991 3.0913 2.5991 22.9531
NCI-N87 CTRP2 2.606 3.6602 2.6053 22.9096
AGS CTRP2 2.6137 3.1956 2.6137 22.8556
SNU-601 CTRP2 2.6726 3.9487 2.6691 22.4752
GSU CTRP2 2.6888 3.2383 2.6888 22.3557
ECC12 CTRP2 2.8057 3.4508 2.8057 21.5766
SNU-719 CTRP2 2.8701 10.1281 0.9932 27.6728
SNU-620 CTRP2 3.0233 3.7706 3.0232 20.1271
SNU-216 CTRP2 3.1782 6.5021 2.7804 20.5037
SH-10-TC CTRP2 3.3394 5.099 3.2866 18.1998
LMSU CTRP2 3.5162 5.3021 3.4467 17.0797
KATO III CTRP2 3.7512 5.6745 3.6322 15.6872
NUGC-3 CTRP2 5.4183 8.6561 4.186 9.1095
MKN45 CTRP2 6.9913 8.513 5.4813 1.0473
SNG-M CTRP2 2.4968 4.116 2.4849 23.6743
SNU-685 CTRP2 2.582 2.9826 2.582 23.067
SNU-1077 CTRP2 2.8033 3.8178 2.8025 21.5952
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ML-1 [Human leukemia] CTRP2 0.0144 13.1287 -3.251 44.5436
8505C CTRP2 0.9577 2.7409 0.9547 33.8983
CAL-62 CTRP2 2.0716 3.2424 2.0709 26.4697
TT2609-C02 CTRP2 2.3769 4.1052 2.3622 24.4825
B-CPAP CTRP2 2.4939 3.1047 2.4939 23.6538
8305C CTRP2 2.5462 4.0317 2.5386 23.3311
SW579 CTRP2 2.5677 3.0088 2.5677 23.1625
CGTH-W-1 CTRP2 2.5709 3.0852 2.5709 23.141
FTC-238 CTRP2 2.5866 3.0101 2.5866 23.0361
FTC-133 CTRP2 2.7113 3.2324 2.7113 22.2057
BHT-101 CTRP2 2.9676 3.7753 2.9675 20.4984
TT CTRP2 4.3593 34.1767 -9.4496 39.6896
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-25 CTRP2 1.4152 2.8126 1.4143 30.8436
SCC-4 CTRP2 1.4935 3.238 1.4884 30.3356
YD-8 CTRP2 1.5128 3.2079 1.5085 30.2043
HSC-4 CTRP2 1.5232 2.2368 1.5232 30.1207
HSC-2 CTRP2 1.5995 1.9942 1.5995 29.6127
PE/CA-PJ15 CTRP2 2.2371 3.0631 2.2371 25.3649
FaDu CTRP2 2.3937 3.1174 2.3937 24.3216
PE/CA-PJ41 (clone D2) CTRP2 2.4534 3.9208 2.4473 23.9441
BICR 6 CTRP2 2.463 3.0167 2.463 23.8598
PE/CA-PJ34 (clone C12) CTRP2 2.4634 3.0558 2.4634 23.8569
SNU-1076 CTRP2 2.5034 2.8784 2.5034 23.5904
PE/CA-PJ49 CTRP2 2.5418 3.2171 2.5418 23.3346
BHY CTRP2 2.571 4.2343 2.5558 23.1912
Detroit 562 CTRP2 2.5905 9.3224 1.0603 28.2731
SNU-1214 CTRP2 2.6136 3.5707 2.6133 22.8573
HSC-3 CTRP2 2.62 3.1023 2.62 22.8138
SNU-46 CTRP2 2.6348 3.97 2.6304 22.7301
YD-10B CTRP2 2.6381 3.0871 2.6381 22.6935
CAL-27 CTRP2 2.6461 3.0927 2.6461 22.6402
CAL-33 CTRP2 2.7018 3.6564 2.7014 22.2701
SCC-9 CTRP2 2.7132 3.8045 2.712 22.197
SNU-899 CTRP2 2.7258 3.8558 2.7241 22.1146
BICR 31 CTRP2 3.5186 6.1678 3.2532 17.7596
BICR 16 CTRP2 3.5335 5.2977 3.466 16.9577
SNU-1041 CTRP2 3.9163 6.8242 3.4704 15.7871
BICR 18 CTRP2 4.2823 5.5615 4.2285 11.9228
BICR 22 CTRP2 4.3365 5.6306 4.275 11.5882
BICR 56 CTRP2 4.4874 6.8011 4.0919 11.8132
SNU-1066 CTRP2 5.8647 10.4833 3.6735 10.3061
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-3 CTRP2 1.6183 3.9927 1.583 29.6054
T24 CTRP2 1.6272 2.1854 1.6272 29.4281
U-BLC1 CTRP2 1.6646 2.7914 1.6644 29.1793
CAL-29 CTRP2 1.7186 3.1002 1.7173 28.8233
253J CTRP2 1.9248 2.9656 1.9247 27.4456
TCCSUP CTRP2 2.0198 3.266 2.0189 26.8156
253J-BV CTRP2 2.1725 3.2506 2.1722 25.7961
KU-19-19 CTRP2 2.362 19.5219 -3.9647 38.804
RT-112 CTRP2 2.4672 2.9457 2.4672 23.832
5637 CTRP2 2.4796 3.8123 2.4762 23.7607
647V CTRP2 2.5325 2.9823 2.5325 23.3966
UM-UC-1 CTRP2 2.5809 4.3363 2.5603 23.1435
JMSU-1 CTRP2 2.618 3.0938 2.618 22.827
KMBC-2 CTRP2 2.6223 3.2483 2.6223 22.7984
SCaBER CTRP2 2.6366 3.0662 2.6366 22.7033
VM-CUB-1 CTRP2 2.6443 3.3674 2.6443 22.652
BC-3C CTRP2 2.8013 3.9694 2.7989 21.6142
639V CTRP2 2.8225 3.5539 2.8225 21.4649
HT-1376 CTRP2 3.5746 5.7236 3.4294 16.9555
HT-1197 CTRP2 4.0357 19.2147 -8.0511 20.6098
SW1710 CTRP2 4.3646 6.3742 4.1116 12.0917
J82 CTRP2 4.5722 11.331 2.0924 19.4401
RT-4 CTRP2 7.5052 19.1014 0.6897 18.3233
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 5.0992 7.936 4.2292 9.6739

References

1 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.