Details of the Drug

General Information of Drug (ID: DMWMPD4)

Drug Name
Vorinostat
Synonyms
NHNPODA; SAHA; SHH; Zolinza; Merck brand of Vorinostat; OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE; SAHA cpd; Suberanilohydroxamic acid; Suberoylanilide hydroxamic acid; Vorinostat MSD; Vorinostat [USAN]; M344; MK0683; SKI390; WIN64652; MK-0683; SAHA, Suberoylanilide hydroxamic acid; SW-064652; Zolinza (TN); Vorinostat (JAN/USAN); N1-hydroxy-N8-phenyloctanediamide; Zolinza, MK-0683, SAHA; N'-hydroxy-N-phenyloctanediamide; N-Hydroxy-N'-phenyl octanediamide; N-Hyrdroxy-N'-phenyloctanediamide; N-hydroxy-N'-phenyloctanediamide; N-hydroxy-N'-phenyl-octane-1,8-diotic acid diamide; Vorinostat (HDAC inhibitor)
Indication
Disease Entry ICD 11 Status REF
Adult acute monocytic leukemia N.A. Approved [1]
Cutaneous T-cell lymphoma 2B01 Approved [2]
Ovarian neoplasm N.A. Approved [1]
Plasma cell myeloma 2A83.1 Approved [1]
Primary cutaneous T-cell lymphoma N.A. Approved [1]
Adult glioblastoma N.A. Investigative [1]
⏷ Show the Full List of Indication(s)
Therapeutic Class
Anticancer Agents
Affected Organisms
Humans and other mammals
ATC Code
L01XH01: Vorinostat
L01XH: Histone deacetylase (HDAC) inhibitors
L01X: OTHER ANTINEOPLASTIC AGENTS
L01: ANTINEOPLASTIC AGENTS
L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 264.32
Logarithm of the Partition Coefficient (xlogp) 1.9
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 3
ADMET Property
BDDCS Class
Biopharmaceutics Drug Disposition Classification System (BDDCS) Class 2: low solubility and high permeability [3]
Clearance
The drug present in the plasma can be removed from the body at the rate of 28 mL/min/kg [4]
Half-life
The concentration or amount of drug in body reduced by one-half in 2 hours [4]
Metabolism
The drug is metabolized via beta-oxidation []
Unbound Fraction
The unbound fraction of drug in plasma is 0.29% [4]
Vd
Fluid volume that would be required to contain the amount of drug present in the body at the same concentration as in the plasma 0.5 L/kg [4]
Adverse Drug Reaction (ADR)
ADR Term Variation Related DOT DOT ID REF
Corneal defect Not Available TGFB1 OTV5XHVH [5]
Chemical Identifiers
Formula
C14H20N2O3
IUPAC Name
N'-hydroxy-N-phenyloctanediamide
Canonical SMILES
C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
InChI
InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
InChIKey
WAEXFXRVDQXREF-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
5311
ChEBI ID
CHEBI:45716
CAS Number
149647-78-9
UNII
58IFB293JI
DrugBank ID
DB02546
TTD ID
D0E7PQ
VARIDT ID
DR00769
INTEDE ID
DR1710
ACDINA ID
D00734
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histone deacetylase 1 (HDAC1) TT6R7JZ HDAC1_HUMAN Inhibitor [6]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Substrate [7]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DEB3CV1 UD2B7_HUMAN Substrate [8]
UDP-glucuronosyltransferase 1A9 (UGT1A9) DE85D2P UD19_HUMAN Substrate [8]
UDP-glucuronosyltransferase 1A3 (UGT1A3) DEF2WXN UD13_HUMAN Substrate [9]
UDP-glucuronosyltransferase 1A8 (UGT1A8) DE2GB8N UD18_HUMAN Substrate [9]
UDP-glucuronosyltransferase 1A7 (UGT1A7) DEZO4N3 UD17_HUMAN Substrate [9]
UDP-glucuronosyltransferase 2B17 (UGT2B17) DEAZDL8 UDB17_HUMAN Substrate [8]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
1,4-alpha-glucan-branching enzyme (GBE1) OTK2N05B GLGB_HUMAN Gene/Protein Processing [10]
1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 (PNPLA3) OTR4990X PLPL3_HUMAN Gene/Protein Processing [10]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (PLCB4) OTPA0QHW PLCB4_HUMAN Gene/Protein Processing [10]
14-3-3 protein epsilon OT3WQXNA 1433E_HUMAN Gene/Protein Processing [11]
17-beta-hydroxysteroid dehydrogenase type 6 (HSD17B6) OTSB55D2 H17B6_HUMAN Gene/Protein Processing [12]
17S U2 SnRNP complex component HTATSF1 (HTATSF1) OTLQ1ZLS HTSF1_HUMAN Gene/Protein Processing [10]
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (GCAT) OT6WZPWV KBL_HUMAN Gene/Protein Processing [10]
2-hydroxyacylsphingosine 1-beta-galactosyltransferase OT17ST61 CGT_HUMAN Gene/Protein Processing [10]
24-hydroxycholesterol 7-alpha-hydroxylase (CYP39A1) OTBAJT4I CP39A_HUMAN Gene/Protein Processing [10]
26S proteasome non-ATPase regulatory subunit 6 (PSMD6) OTX59EGK PSMD6_HUMAN Gene/Protein Processing [10]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Adult acute monocytic leukemia
ICD Disease Classification
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Histone deacetylase 1 (HDAC1) DTT HDAC1 6.27E-01 0.11 0.33
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME UGT1A1 5.20E-01 -3.27E-03 -2.84E-02
UDP-glucuronosyltransferase 2B17 (UGT2B17) DME UGT2B17 6.02E-01 -1.60E+00 -4.84E-01
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 0.0551 3.0242 -0.1666 33.8456
ES8 GDSC1; GDSC2 0.041 1.6088 0.0268 32.9955
ES5 GDSC1; GDSC2 0.2914 2.0399 0.2569 30.5852
EW-3 GDSC1; GDSC2 0.3591 2.1958 0.3121 29.9696
ES1 GDSC1; GDSC2 0.4381 2.0949 0.4059 29.1025
EW-1 GDSC1; GDSC2 0.5351 1.8695 0.5229 28.0277
EW-7 GDSC1; GDSC2 0.5443 3.3735 0.2764 29.2391
U2OS GDSC1; GDSC2; CTRP2; CTRP1 0.7243 3.4738 0.6567 29.7797
EW-12 GDSC2 0.7449 1.8932 0.7374 25.8983
EW-18 GDSC1; GDSC2 0.7648 3.0476 0.6011 26.5061
TC-71 GDSC1; GDSC2 0.7725 1.7925 0.7687 25.6024
MHH-ES-1 GDSC1; GDSC2; CTRP2 0.7785 2.1925 0.7768 28.4258
CHSA0108 GDSC1; GDSC2 0.7923 2.9771 0.6472 26.1338
EW-22 GDSC1; GDSC2 0.84 2.1628 0.8208 25.0031
NOS-1 [Human HNSCC] GDSC1; GDSC2 0.9011 2.5287 0.8468 24.5704
SK-N-MC CTRP2 0.9094 2.0899 0.9089 27.5494
EW-11 GDSC1; GDSC2 0.936 2.0507 0.9269 23.9886
CADO-ES1 GDSC1; GDSC2 1.0618 3.5433 0.7916 24.1047
SK-ES-1 GDSC1; GDSC2; CTRP2 1.1597 2.8904 1.1484 25.9181
EW-13 GDSC1; GDSC2 1.1743 4.0432 0.748 23.8318
ES7 GDSC1; GDSC2 1.1966 2.6849 1.1402 21.6168
HOS GDSC1; GDSC2; CTRP2 1.2464 2.5033 1.245 25.3075
A-673 GDSC1; GDSC2; CTRP2 1.2858 3.4724 1.2412 25.1905
EW-16 GDSC1; GDSC2 1.2897 3.0084 1.1812 20.9568
HuO9 GDSC1; GDSC2 1.3099 3.345 1.1199 21.1913
SW1353 CTRP2 1.3376 3.021 1.3255 24.7358
ES4 GDSC1; GDSC2 1.431 3.2431 1.2793 19.7716
EW-24 GDSC1; GDSC2 1.6461 3.8014 1.3428 18.4538
SK-PN-DW GDSC1; GDSC2 1.7826 3.4764 1.5974 16.4324
TC71 CTRP2 1.7844 3.3141 1.7716 21.7612
ES6 GDSC1; GDSC2 1.8301 3.6429 1.5961 16.2274
NY GDSC1; GDSC2 2.0381 5.1214 1.2125 17.5977
CAL-72 GDSC1; GDSC2 2.1387 4.683 1.5107 15.4409
SaOS-2 GDSC1; GDSC2; CTRP2 2.3294 3.7458 2.3106 18.151
SJSA-1 GDSC1; GDSC2 2.3401 5.0882 1.5293 14.5596
HuO-3N1 GDSC1; GDSC2 2.5219 5.3159 1.5992 13.4706
CAL-78 GDSC1; GDSC2; CTRP2 2.5412 4.5583 2.4283 17.0643
Hs 888.T CTRP2 2.7392 8.0118 1.3754 20.4572
CHSA8926 GDSC1; GDSC2 2.9 3.9108 2.6297 5.7865
MG-63 GDSC1; GDSC2; CTRP2 2.9836 6.7449 2.1789 16.716
H-EMC-SS GDSC1; GDSC2 2.9846 6.1442 1.6207 11.7761
CHSA0011 GDSC1; GDSC2 3.3539 5.3727 2.323 6.2322
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 3.4006 8.3828 1.8646 16.8764
U-CH2 GDSC2 3.4467 5.4948 2.3377 5.878
Hs 822.T CTRP2 5.2213 6.6507 4.3835 2.4549
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 219 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 0.9045 2.4135 0.9012 27.5915
JK1 CTRP2 1.412 2.9707 1.4036 24.2278
JM1 GDSC1; GDSC2; CTRP2 -0.3608 1.3205 -0.3622 36.0148
KMS-26 CTRP2 -2.0171 -0.7672 -2.0171 47.0446
Karpas-45 GDSC1; GDSC2 -1.6759 -0.3865 -1.6761 50.1537
NB4 GDSC1; GDSC2; CTRP2 -1.6051 -0.5798 -1.6051 44.3001
CRO-AP2 GDSC1; GDSC2 -1.5517 0.6495 -1.567 48.9219
DoHH2 GDSC1; GDSC2; CTRP2 -1.5444 1.4294 -1.5651 43.947
BCP-1 CTRP2 -1.5331 3.3853 -1.7584 44.2488
Kasumi-1 GDSC1; GDSC2; CTRP2 -1.489 0.1309 -1.4892 43.527
BE-13 GDSC1; GDSC2 -1.4884 0.2322 -1.4918 48.2783
SU-DHL-5 GDSC1; GDSC2; CTRP1 -1.3675 0.0296 -1.3676 55.489
SUP-B8 GDSC1; GDSC2 -1.2546 2.7642 -1.5321 46.4311
SKM-1 GDSC1; GDSC2; CTRP2; CTRP1 -1.1933 0.0858 -1.1933 42.1924
ALL-PO GDSC1; GDSC2 -1.1843 1.3234 -1.2275 45.3438
Karpas-1106P GDSC1; GDSC2 -1.0301 0.5551 -1.0335 43.6873
RPMI-8866 GDSC1 -1.0069 1.3846 -1.047 53.9048
SU-DHL-16 GDSC1; GDSC2 -0.9627 -0.0816 -0.9627 42.9964
Kasumi-2 CTRP2 -0.9573 1.5208 -0.9683 40.0182
SEM CTRP2 -0.9473 0.3791 -0.9473 39.9176
EoL-1 GDSC1; GDSC2; CTRP2 -0.9453 0.9223 -0.9468 39.909
NU-DUL-1 GDSC1; GDSC2; CTRP2; CTRP1 -0.9316 0.5057 -0.9317 40.468
NKM-1 GDSC1; GDSC2 -0.9261 1.202 -0.9499 42.7228
MOLM-16 GDSC1; GDSC2; CTRP2; CTRP1 -0.8937 0.5083 -0.8937 40.2179
PL21 CTRP2; CTRP1 -0.8821 0.18 -0.8821 40.1415
OCI-Ly7 GDSC1; GDSC2 -0.8772 0.4783 -0.8786 42.1448
MY-M12 GDSC1; GDSC2 -0.8737 0.9507 -0.8842 42.1482
Peer CTRP2 -0.8699 0.0248 -0.8699 39.4018
MOLT-13 GDSC1; GDSC2; CTRP2 -0.8696 1.0537 -0.8716 39.4062
RCH-ACV GDSC1; GDSC2; CTRP2 -0.8585 1.1546 -0.8614 39.3352
Karpas-231 GDSC1; GDSC2 -0.8535 0.5966 -0.8558 41.9112
KMS-21-BM CTRP2 -0.8417 1.2926 -0.8462 39.2285
CTB-1 GDSC1; GDSC2 -0.8347 2.0021 -0.934 42.0764
MV4-11 GDSC1; GDSC2; CTRP2 -0.809 0.4295 -0.809 38.996
A3/Kawakami GDSC1; GDSC2; CTRP2 -0.7924 0.4889 -0.7924 38.8857
MOLM-13 GDSC1; GDSC2; CTRP2 -0.7891 1.0923 -0.791 38.8696
M-07e CTRP2 -0.7438 0.7811 -0.7441 38.5628
JSC-1 GDSC1; GDSC2 -0.7281 0.7648 -0.7316 40.6584
RPMI-8402 GDSC1; GDSC2; CTRP2 -0.6874 0.3773 -0.6874 38.1863
BC-3 GDSC2 -0.6685 0.493 -0.669 40.0468
ALL-SIL GDSC1; GDSC2 -0.6255 0.6871 -0.6271 39.6206
H9 GDSC1; GDSC2 -0.6176 0.928 -0.6228 39.558
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 -0.6085 0.9195 -0.6089 37.6617
SR GDSC1; GDSC2; CTRP2 -0.5732 1.4107 -0.5767 37.4367
KMS-12-BM GDSC1; GDSC2; CTRP2 -0.5703 0.9197 -0.5706 37.407
HuT 78 CTRP2 -0.5159 1.6716 -0.5234 37.0681
KMOE-2 GDSC1; GDSC2 -0.488 1.4957 -0.5142 38.3555
MHH-PREB-1 GDSC1; GDSC2 -0.4445 2.0068 -0.5183 38.1295
MOLT-4 GDSC1; GDSC2 -0.4173 1.2079 -0.4266 37.5687
ATN-1 GDSC1; GDSC2 -0.4171 1.0916 -0.423 37.5508
DB GDSC1; GDSC2; CTRP2 -0.417 1.5415 -0.4209 36.3976
P12-Ichikawa GDSC1; GDSC2; CTRP2 -0.3746 0.571 -0.3747 36.1025
WSU-NHL GDSC1; GDSC2 -0.3718 1.3239 -0.3846 37.1292
Loucy GDSC1; GDSC2 -0.3581 2.2085 -0.4541 37.3672
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 -0.3527 0.9682 -0.3528 36.6534
BL-70 CTRP2; CTRP1 -0.3123 0.9618 -0.3124 36.3871
KMS-34 CTRP2 -0.3043 1.2675 -0.3051 35.6363
RPMI-8226 GDSC1; GDSC2; CTRP2; CTRP1 -0.2976 1.7343 -0.3023 36.305
KY821 GDSC1; GDSC2 -0.2633 1.8313 -0.3067 36.1867
NALM-6 GDSC1; GDSC2; CTRP2 -0.2491 1.2638 -0.2497 35.268
JVM-3 GDSC1; GDSC2; CTRP2 -0.224 2.2224 -0.2434 35.1626
OCI-M1 GDSC1; GDSC2; CTRP2 -0.2058 0.7553 -0.2058 34.9776
A4/Fukuda GDSC1; GDSC2; CTRP2 -0.1973 1.1762 -0.1976 34.9218
SUP-T1 GDSC1; GDSC2; CTRP2 -0.1948 1.3378 -0.1956 34.9069
Ri-1 CTRP2 -0.1913 2.1837 -0.2082 34.9365
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 -0.1882 1.3363 -0.1888 35.5707
CCRF-CEM GDSC1; GDSC2 -0.1818 1.4387 -0.1944 35.2228
SUP-M2 GDSC1; GDSC2; CTRP2 -0.1732 1.1535 -0.1734 34.7611
QIMR-WIL GDSC1; GDSC2 -0.1578 2.3337 -0.2586 35.3994
Farage GDSC1; GDSC2 -0.1578 2.0998 -0.2251 35.2438
Mino CTRP2 -0.1526 0.8103 -0.1526 34.6234
GA-10 GDSC1; GDSC2; CTRP2 -0.1507 2.4613 -0.1804 34.7077
697 GDSC1; GDSC2; CTRP2 -0.1405 0.9456 -0.1405 34.5426
KOPN-8 GDSC1; GDSC2 -0.129 1.6203 -0.1496 34.7326
CA46 GDSC1; GDSC2; CTRP2 -0.1055 1.4825 -0.1066 34.313
KE-37 GDSC1; GDSC2; CTRP2 -0.1 1.0518 -0.1001 34.273
P30/OHK GDSC1; GDSC2 -0.0954 0.8848 -0.0958 34.2949
RS4;11 GDSC1; GDSC2 -0.0889 2.1701 -0.1608 34.5774
KE-97 CTRP2; CTRP1 -0.0811 1.2303 -0.0812 34.8634
Jurkat GDSC1; GDSC2; CTRP2 -0.0498 1.1565 -0.0499 33.9384
OCI-Ly10 CTRP2; CTRP1 -0.0483 2.9576 -0.1057 34.8315
SET-2 CTRP2 -0.0452 1.107 -0.0453 33.9079
JVM-2 GDSC1; GDSC2; CTRP2 -0.0386 4.3192 -0.3229 34.7564
AMO1 GDSC1; GDSC2; CTRP2; CTRP1 -0.0193 1.3984 -0.0197 34.4569
BV-173 GDSC1; GDSC2; CTRP2 -0.0138 2.2186 -0.0276 33.7442
NU-DHL-1 CTRP2 -0.0073 1.2539 -0.0075 33.6559
BC-1 GDSC1; GDSC2 0.0041 0.9834 0.0036 33.2974
NOMO-1 GDSC1; GDSC2; CTRP2; CTRP1 0.0127 1.789 0.0101 34.2535
KO52 CTRP2 0.0352 1.3148 0.035 33.3725
CML-T1 GDSC1; GDSC2; CTRP2 0.0694 1.5078 0.0688 33.1462
HEL GDSC1; GDSC2; CTRP2 0.0749 1.1451 0.0749 33.1075
L-1236 GDSC1; GDSC2; CTRP2 0.1032 1.4408 0.1028 32.9204
P32/ISH GDSC1; GDSC2 0.106 2.0232 0.0633 32.4855
NK-92MI GDSC2 0.1126 1.5078 0.1046 32.2461
KMS-28BM CTRP2 0.1313 4.8496 -0.2655 33.9851
KG-1 GDSC1; GDSC2 0.1372 1.574 0.1272 32.0092
VL51 GDSC1; GDSC2 0.1513 1.7775 0.1311 31.9187
MOLT-16 GDSC1; GDSC2; CTRP2 0.1993 1.0804 0.1993 32.2788
JJN-3 GDSC1; GDSC2; CTRP2 0.2133 2.2277 0.2039 32.2169
MM1.S GDSC1; GDSC2; CTRP2 0.2203 2.1279 0.2136 32.1613
SU-DHL-6 GDSC1; GDSC2; CTRP2 0.2218 1.4171 0.2216 32.1294
OCI-AML-5 GDSC1; CTRP2 0.2261 1.5896 0.2256 32.1019
ROS-50 GDSC1; GDSC2 0.2269 2.4634 0.134 31.5237
P3HR-1 CTRP2; CTRP1 0.229 2.0092 0.2256 32.8309
CTV-1 GDSC1; GDSC2 0.2414 1.5387 0.235 30.9455
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 0.2597 1.9349 0.2568 31.8861
Ki-JK CTRP2 0.2716 2.6644 0.2447 31.8865
MOLT-3 CTRP2 0.2789 1.007 0.2789 31.7482
HL-60 GDSC1; GDSC2; CTRP2 0.2789 1.2189 0.2789 31.7484
Ramos.2G6.4C10 GDSC1; GDSC2 0.2925 2.5513 0.1898 30.9167
SCC-3 GDSC2 0.2942 1.513 0.2895 30.4074
DND-41 GDSC1; GDSC2; CTRP2 0.2946 1.9636 0.2917 31.6535
ME1 GDSC1; GDSC2 0.297 2.3602 0.225 30.7178
EM-2 GDSC1; GDSC2; CTRP2 0.3032 1.5171 0.303 31.5873
EJM GDSC1; GDSC2; CTRP2; CTRP1 0.3089 2.5502 0.2923 32.3476
CMK GDSC1; CTRP2 0.3119 1.262 0.3119 31.5288
OPM-2 GDSC1; GDSC2; CTRP2 0.3121 1.2655 0.3121 31.5273
YT GDSC1; GDSC2 0.3149 2.7632 0.1742 30.8826
JURL-MK1 GDSC1; CTRP2 0.3176 1.756 0.3167 31.4937
AML-193 CTRP2 0.3235 1.6312 0.3231 31.4529
JeKo-1 GDSC1; GDSC2; CTRP2 0.3252 1.8921 0.3233 31.446
KMS-11 GDSC1; GDSC2; CTRP2; CTRP1 0.3265 2.0029 0.324 32.1852
MOLP-8 GDSC1; GDSC2; CTRP2 0.3324 1.8215 0.3311 31.3966
Sc-1 GDSC1 0.3357 1.4806 0.3323 37.3484
THP-1 GDSC1; GDSC2; CTRP2; CTRP1 0.3446 1.7264 0.344 32.0598
Namalwa GDSC1; GDSC2; CTRP2 0.3555 1.9893 0.3528 31.2474
HEL 92.1.7 CTRP2 0.3623 1.236 0.3623 31.1926
PF-382 GDSC1; GDSC2; CTRP2 0.3817 1.7398 0.381 31.0658
SK-MM-2 GDSC1; GDSC2 0.3835 1.7076 0.3743 29.5337
HAL-01 GDSC1; GDSC2 0.3898 2.3347 0.3276 29.7387
ST486 GDSC1; GDSC2; CTRP2 0.3903 1.5293 0.3902 31.0065
TK [Human B-cell lymphoma] GDSC1; GDSC2 0.4128 2.9269 0.2457 30.0384
WIL2 NS GDSC1; GDSC2 0.4254 1.9167 0.4067 29.1613
Ku812 GDSC1; GDSC2; CTRP2; CTRP1 0.4334 1.7148 0.433 31.474
OCI-Ly3 CTRP2 0.4457 1.9117 0.4443 30.6417
DEL GDSC1; GDSC2; CTRP2 0.4793 2.0325 0.4771 30.4206
MHH-CALL-4 GDSC2; CTRP2 0.4795 2.0808 0.4768 30.421
HT GDSC1; GDSC2; CTRP2; CTRP1 0.5142 2.2201 0.5106 30.9522
Mono-Mac-6 GDSC1; GDSC2; CTRP2 0.5314 3.5107 0.4374 30.3809
U-698-M GDSC1; GDSC2 0.5395 1.9355 0.5237 28.0018
OCI-AML-2 GDSC1; GDSC2; CTRP2 0.5406 1.9215 0.5396 30.0084
SUP-B15 GDSC1; GDSC2; CTRP2 0.5486 2.3047 0.5428 29.9708
MLMA GDSC1; GDSC2 0.5491 2.6824 0.4434 28.365
P31/FUJ GDSC1; GDSC2; CTRP2 0.5493 1.9433 0.5483 29.9504
Karpas-422 GDSC1; GDSC2; CTRP2 0.557 2.8564 0.5286 29.9907
F-36P CTRP2 0.5665 2.4255 0.558 29.8608
EHEB GDSC1; CTRP2 0.5819 2.9195 0.5503 29.8356
KMS-27 CTRP2 0.5947 2.4572 0.5859 29.674
BONNA-12 GDSC2 0.6043 2.6779 0.5038 27.7852
Karpas-299 GDSC1; GDSC2; CTRP2 0.6109 1.9957 0.6098 29.5402
TUR GDSC1; GDSC2 0.619 2.5764 0.5371 27.5417
KHM-1B CTRP2 0.629 2.6508 0.614 29.4662
BALL-1 GDSC1; GDSC2 0.6404 3.5087 0.3424 28.4406
HPB-ALL CTRP2 0.6458 1.6395 0.6457 29.3046
LAMA-84 GDSC1; GDSC2; CTRP2 0.6571 1.7631 0.657 29.2292
KMS-20 CTRP2 0.6637 3.0253 0.6278 29.3049
SUP-HD1 GDSC1; GDSC2; CTRP2 0.6642 3.0844 0.6236 29.3174
LP-1 GDSC1; GDSC2; CTRP2; CTRP1 0.6652 1.8898 0.6648 29.9466
NCI-H929 GDSC1; GDSC2; CTRP2 0.6873 1.9576 0.6867 29.0297
DG-75 GDSC1; GDSC2 0.7185 2.8255 0.5993 26.738
MOTN-1 CTRP2 0.7316 1.9459 0.7312 28.7338
IM-9 GDSC1; GDSC2 0.7453 2.1976 0.719 25.9897
Reh GDSC1; GDSC2; CTRP2 0.7518 2.1782 0.7501 28.6034
Pfeiffer CTRP2 0.7583 2.0168 0.7577 28.5567
Mono-Mac-1 CTRP2 0.7598 3.9057 0.6229 29.0063
L-363 GDSC1; GDSC2; CTRP2 0.762 1.7287 0.762 28.5299
SU-DHL-4 GDSC1; GDSC2; CTRP2; CTRP1 0.7945 2.1347 0.7936 29.0962
KCL-22 GDSC1; GDSC2; CTRP2 0.804 2.0437 0.8034 28.2521
VAL GDSC1; GDSC2 0.8113 3.497 0.5323 26.6465
MHH-CALL-2 GDSC1; GDSC2 0.8342 2.0334 0.8229 25.0217
RL GDSC1; GDSC2; CTRP2 0.8472 2.2425 0.8455 27.9682
Daudi GDSC1; GDSC2; CTRP2 0.8751 2.9034 0.8551 27.8433
Jiyoye GDSC1; GDSC2 0.8759 2.3252 0.8443 24.7064
ME1 CTRP2 0.8838 3.3984 0.825 27.9161
MOLM-6 CTRP2 0.8875 2.3088 0.8854 27.7009
EB1 CTRP2 0.8977 2.209 0.8966 27.6297
LC4-1 GDSC1; GDSC2 0.8991 3.7849 0.5383 26.2051
ML-2 GDSC1; GDSC2 0.9112 2.2742 0.8863 24.3182
GDM-1 GDSC1; GDSC2; CTRP2; CTRP1 0.9148 2.7142 0.9062 28.3291
HDLM-2 GDSC1; GDSC2; CTRP2 0.915 3.3136 0.8664 27.6739
GR-ST GDSC1; GDSC2 0.9165 4.0282 0.4749 26.4584
PL-21 GDSC1; GDSC2 0.9209 3.3741 0.6872 25.3154
Raji GDSC1; GDSC2; CTRP2 0.9219 2.6501 0.9136 27.4926
L-428 GDSC1; GDSC2; CTRP2 0.9384 2.4091 0.9355 27.3644
RPMI-6666 GDSC1; GDSC2; CTRP2 0.9426 2.6392 0.935 27.3523
Hs 445 GDSC2 0.956 3.6015 0.6585 25.3052
MN-60 GDSC1; GDSC2 0.9696 4.1456 0.4906 26.133
NCO2 CTRP2 0.975 2.6121 0.9687 27.1323
SU-DHL-1 GDSC2; CTRP2 1.0511 2.7038 1.0437 26.6287
TF-1 CTRP2 1.0709 1.8852 1.0709 26.472
U266B1 GDSC1; GDSC2; CTRP2 1.1191 2.9995 1.1019 26.2084
Granta-519 GDSC1; GDSC2; CTRP2 1.1373 3.1851 1.1095 26.1228
OCI-Ly19 GDSC1; GDSC2; CTRP2 1.1506 2.9435 1.1369 25.9871
SUP-T11 CTRP2 1.1679 2.8903 1.1568 25.8626
SU-DHL-8 GDSC2; CTRP2 1.1682 2.2795 1.1677 25.8252
KYO-1 CTRP2 1.1695 2.163 1.1693 25.8157
HC-1 GDSC1; GDSC2 1.191 3.8511 0.8331 23.2933
SU-DHL-10 GDSC2; CTRP2 1.2195 1.9303 1.2195 25.4818
L-540 GDSC1; GDSC2; CTRP2 1.2368 2.5488 1.2348 25.3735
MEG-01 GDSC1; GDSC2 1.2401 2.672 1.1887 21.1542
U-937 CTRP2; CTRP1 1.2482 2.2304 1.248 26.1041
EB2 GDSC1; GDSC2 1.278 2.3627 1.2626 20.5887
SIG-M5 GDSC2; CTRP2 1.2847 2.3184 1.2843 25.049
MC116 GDSC1; GDSC2; CTRP2; CTRP1 1.3001 2.5912 1.2986 25.7663
KMS-18 CTRP2 1.3124 2.5502 1.3109 24.868
K-562 GDSC1; GDSC2; CTRP2 1.3906 2.8819 1.3843 24.3631
RC-K8 GDSC1; GDSC2 1.4888 3.1029 1.3766 18.9799
CESS GDSC1; GDSC2 1.5944 3.4196 1.4091 18.317
Hs 611.T CTRP2 1.675 7.3225 0.5665 26.3511
MHH-CALL-3 CTRP2 1.8102 9.3559 -0.1698 28.35
ARH-77 GDSC1; GDSC2 1.8161 3.0627 1.7414 15.4979
KM-H2 GDSC1; GDSC2; CTRP2 1.8851 3.7248 1.8475 21.1741
MOLP-2 CTRP2 2.1113 3.5205 2.0982 19.5843
HD-MY-Z CTRP2 2.3827 4.5215 2.2638 18.1406
Karpas-620 GDSC1; GDSC2; CTRP2 5.9675 8.1997 4.1536 2.2924
Toledo CTRP2 6.4511 10.6655 3.3021 5.0095
BL-41 GDSC1; GDSC2; CTRP2 6.9072 8.3 4.5885 0.2178
REC-1 CTRP2 7.2375 9.69 4.1951 0.9755
KMM-1 CTRP2 7.5687 10.8417 3.881 1.6732
⏷ Show the Full List of 219 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 2.2589 4.0075 2.2123 18.715
TE-4 GDSC1; GDSC2 -0.4038 0.9883 -0.4073 37.4052
TE-1 GDSC1; GDSC2; CTRP2 0.6273 2.3317 0.6221 29.4448
TE-15 GDSC1 0.9019 2.4607 0.8565 30.5355
T.T GDSC1; GDSC2 0.997 2.7045 0.9227 23.712
TE-8 GDSC1; GDSC2 1.0652 2.8518 0.9697 23.1389
KYSE-410 GDSC1; GDSC2; CTRP2; CTRP1 1.8236 3.7288 1.7893 22.4259
OE19 GDSC1; GDSC2; CTRP2 1.869 4.6127 1.6866 21.7842
OE33 GDSC1; GDSC2; CTRP2 1.9522 3.9512 1.8934 20.7997
TE-6 GDSC1; GDSC2 1.9587 5.5587 0.9328 19.5342
KYSE-70 GDSC1; GDSC2; CTRP2 2.0048 4.0889 1.9308 20.5016
KYSE-270 GDSC1; GDSC2 2.2669 4.7593 1.6071 14.3685
TE-5 GDSC1; GDSC2; CTRP2 2.3284 5.1404 2.0535 19.0585
COLO 680N GDSC1; GDSC2; CTRP2 2.3845 5.0445 2.1416 18.5699
KYSE-140 GDSC1; GDSC2; CTRP2; CTRP1 2.4011 6.6828 1.646 21.2112
TE-14 CTRP2 2.4878 4.3707 2.4052 17.3141
OE21 GDSC1; GDSC2; CTRP2 2.6281 4.5693 2.5203 16.4675
KYSE-450 GDSC1; GDSC2; CTRP2; CTRP1 2.6645 5.1909 2.4371 17.5565
KYSE-180 GDSC1; GDSC2; CTRP2 2.6841 5.6001 2.2979 17.1039
EC-GI-10 GDSC1; GDSC2; CTRP2 2.7352 4.4941 2.6504 15.6744
TE-9 GDSC1; GDSC2; CTRP2 2.7677 4.3411 2.7104 15.3623
KYSE-510 GDSC1; GDSC2; CTRP2 2.7685 4.792 2.6247 15.6601
KYSE-30 CTRP2 2.7964 4.8843 2.6328 15.5448
TE-10 GDSC1; GDSC2; CTRP2 2.8498 4.9349 2.6784 15.2173
KYSE-150 GDSC1; GDSC2; CTRP2 2.9004 4.2974 2.8582 14.4263
TE-11 GDSC1; GDSC2; CTRP2 3.442 5.6682 3.0929 11.9377
KYSE-520 GDSC1; GDSC2; CTRP2 4.552 9.4456 2.421 11.9938
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 3.579 8.2868 2.0839 15.5691
HuP-T4 GDSC1; GDSC2; CTRP2; CTRP1 1.3118 4.0214 1.2114 26.0211
MIA PaCa-2 GDSC1; GDSC2; CTRP2 1.3416 2.7603 1.3375 24.6822
PSN1 GDSC1; GDSC2; CTRP2 1.698 3.8412 1.6368 22.5013
PaTu 8988s CTRP2 1.7016 5.4158 1.2885 23.7187
PaTu 8902 GDSC1; GDSC2; CTRP2; CTRP1 1.9391 3.5466 1.9225 21.6055
L3.3 CTRP2 1.9958 4.2322 1.8988 20.6408
Hs 766T GDSC1; GDSC2; CTRP2 2.0262 5.5559 1.5979 21.6233
PL4 GDSC1; GDSC2 2.0854 3.9524 1.76 14.1963
DAN-G GDSC1; GDSC2; CTRP2 2.1336 4.0934 2.0678 19.6153
QGP-1 GDSC1; GDSC2; CTRP2; CTRP1 2.1499 5.0774 1.9056 21.0024
BxPC-3 GDSC1; GDSC2; CTRP2 2.1799 4.7836 1.9854 19.7577
TCC-Pan2 CTRP2 2.2377 3.6566 2.2212 18.7537
Panc 08.13 GDSC1; GDSC2; CTRP2 2.2456 4.5351 2.1124 19.1038
KP-3 GDSC1; GDSC2; CTRP2; CTRP1 2.2946 5.1915 2.0332 20.1109
SUIT-2 GDSC1; GDSC2; CTRP2; CTRP1 2.3487 4.6755 2.2153 19.305
PK-59 CTRP2 2.3534 3.7896 2.3324 17.9982
KP-4 GDSC1; GDSC2; CTRP2 2.499 3.8687 2.4783 17.0274
SNU-213 CTRP2 2.5567 6.2017 1.9444 18.7945
Capan-1 GDSC1; GDSC2; CTRP2 2.6097 4.4264 2.527 16.5026
Panc 05.04 CTRP2 2.6256 4.3933 2.5497 16.3732
Panc 10.05 GDSC1; GDSC2; CTRP2; CTRP1 2.6644 4.6324 2.5655 17.1058
HuP-T3 GDSC1; GDSC2; CTRP2 2.7683 6.6899 1.9761 18.0837
Panc 04.03 GDSC1; GDSC2; CTRP2 2.7884 5.1716 2.5464 15.8807
HPAC GDSC1; GDSC2; CTRP2; CTRP1 2.8029 5.2215 2.5799 16.6303
AsPC-1 GDSC1; GDSC2; CTRP2 2.8236 5.5702 2.4592 16.0967
Panc 03.27 GDSC1; GDSC2; CTRP2; CTRP1 2.9799 4.9674 2.8378 15.1785
CFPAC-1 GDSC1; GDSC2; CTRP2; CTRP1 3.0424 6.3406 2.4619 16.3749
KP-1N GDSC1; GDSC2 3.1847 5.1841 2.2742 7.0435
SU.86.86 GDSC1; GDSC2 3.2373 6.3751 1.7243 10.3502
KP-2 GDSC1; GDSC2; CTRP2 3.511 6.1265 2.9881 12.1469
Capan-2 GDSC1; GDSC2; CTRP2; CTRP1 3.5881 6.2682 3.0699 12.5717
MZ-PC-1 GDSC1; GDSC2 3.6281 6.7698 1.846 8.4808
PK-45H CTRP2 3.6707 5.9867 3.2133 10.8395
YAPC GDSC1; GDSC2; CTRP2 3.7283 6.3796 3.1081 11.0963
HPAF-II GDSC1; GDSC2; CTRP2 3.8086 7.6306 2.6179 12.8611
SW1990 GDSC1; GDSC2; CTRP2 3.8346 5.7249 3.4914 9.3162
Panc 02.03 GDSC1; GDSC2; CTRP2 3.9889 6.69 3.2343 9.9254
PaTu 8988t GDSC1; GDSC2; CTRP2 4.9825 6.8346 4.0972 4.1026
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 3.12 11.5653 0.0681 24.1171
CHL-1 GDSC1; GDSC2 -0.162 2.5268 -0.2963 35.5927
SK-MEL-5 GDSC1; GDSC2; CTRP2; CTRP1 0.0646 1.9876 0.0597 33.9189
G-mel GDSC1; GDSC2 0.1016 1.8156 0.0769 32.4396
G-361 GDSC1; GDSC2; CTRP2; CTRP1 0.2163 3.4226 0.1239 33.2036
451Lu GDSC1; GDSC2 0.4198 2.7608 0.2885 29.788
COLO 741 CTRP2; CTRP1 0.5923 11.9916 -2.5184 37.99
Mel Ho GDSC1; GDSC2; CTRP2 0.7477 2.7422 0.7319 28.678
IGR-1 GDSC1; GDSC2; CTRP2 1.05 2.9793 1.0316 26.6729
SK-MEL-2 GDSC1; GDSC2; CTRP2 1.0675 3.2028 1.0355 26.6021
LOX-IMVI GDSC1; GDSC2; CTRP2 1.1775 3.553 1.1186 25.9603
A-375 GDSC1; GDSC2; CTRP2; CTRP1 1.2274 3.0489 1.2139 26.2851
Hs 938.T GDSC1; GDSC2 1.2604 3.146 1.1177 21.4325
COLO 783 GDSC1; GDSC2 1.2829 3.2198 1.1237 21.2954
WM35 GDSC1; GDSC2 1.284 3.0752 1.16 21.096
A-431 GDSC1; GDSC2 1.3511 3.3759 1.1561 20.8058
Hs 936.T CTRP2; CTRP1 1.3527 4.1192 1.2402 25.7926
MZ-MEL-2 GDSC1; GDSC2 1.4012 3.8371 1.0655 21.0782
IGR-37 GDSC1; GDSC2; CTRP2 1.4479 3.5779 1.4015 24.1168
M14 GDSC1; GDSC2 1.5497 3.7007 1.2725 19.2711
MeWo GDSC1; GDSC2; CTRP2 1.6311 4.1518 1.5196 23.12
RPMI-7951 GDSC1; GDSC2; CTRP2 1.6395 3.0804 1.6323 22.708
HMV-II GDSC1; GDSC2 1.7072 5.0166 0.9217 20.594
DJM-1 GDSC1; GDSC2 1.7187 5.0606 0.9143 20.5899
A101D GDSC1; GDSC2; CTRP2 1.7924 3.2215 1.7836 21.6947
WM88 CTRP2 1.8235 4.3108 1.699 21.8839
Hs 852.T CTRP2; CTRP1 1.8707 5.8447 1.3744 23.7316
A-388 GDSC1; GDSC2 1.8948 4.3239 1.4103 17.0117
GAK GDSC1; GDSC2 1.9129 3.2543 1.8021 14.7208
IPC-298 GDSC1; GDSC2; CTRP2 1.9183 4.7773 1.7018 21.5768
Hs 944.T CTRP2; CTRP1 1.9386 4.122 1.8673 21.7931
SK-MEL-30 GDSC1; GDSC2; CTRP2 1.9573 4.1672 1.8679 20.8711
LB2518-MEL GDSC1; GDSC2 1.9661 4.5949 1.3713 16.9487
UACC-257 GDSC1; GDSC2; CTRP2 2.0063 5.0353 1.7314 21.2
HT-144 GDSC1; GDSC2; CTRP2 2.093 3.8331 2.0558 19.7879
IST-MEL1 GDSC1; GDSC2 2.1147 3.8114 1.8445 13.5885
COLO 829 GDSC1; GDSC2; CTRP2 2.137 5.674 1.6797 20.9947
UACC-62 GDSC1; GDSC2; CTRP2 2.1421 3.4537 2.1329 19.3661
LB373-MEL-D GDSC1; GDSC2 2.1527 4.0006 1.8128 13.6095
CP66-MEL GDSC1; GDSC2 2.1624 4.0975 1.7844 13.7344
Hs 940.T GDSC1; GDSC2 2.1951 4.1406 1.8013 13.5014
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 2.2145 4.3233 2.1333 20.0091
WM266-4 CTRP2 2.2631 3.8128 2.2363 18.6195
SK-MEL-3 GDSC1; GDSC2; CTRP2 2.3435 4.8932 2.1367 18.713
Mel JuSo GDSC1; GDSC2; CTRP2 2.3606 4.6814 2.206 18.4138
VMRC-MELG GDSC1; GDSC2 2.37 4.3007 1.9157 12.1232
Hs 294T CTRP2 2.3889 4.4514 2.2841 18.0503
A2058 GDSC1; GDSC2; CTRP2 2.4248 3.9316 2.3954 17.5511
K029AX CTRP2 2.4865 4.0864 2.4444 17.1832
COLO 792 GDSC1; GDSC2; CTRP2 2.5735 6.3522 1.9046 18.897
COLO 800 GDSC1; GDSC2; CTRP2 2.619 4.4888 2.5259 16.4768
MDA-MB-435S CTRP2 2.644 4.6724 2.5162 16.4323
COLO 679 GDSC1; GDSC2 2.6613 5.0078 1.8806 11.2455
SK-MEL-31 GDSC1; GDSC2; CTRP2 2.6696 4.3781 2.5996 16.0596
MZ-MEL-7 GDSC1; GDSC2 2.6861 7.6355 0.6147 18.7268
WM278 GDSC1; GDSC2 2.6983 4.0276 2.3725 8.11
SH-4 GDSC1; GDSC2 2.7661 5.1866 1.8937 10.7979
MMAc-SF GDSC1; GDSC2 2.7781 5.9782 1.5172 13.0896
CP50-MEL-B GDSC1; GDSC2 2.8433 5.7473 1.6904 11.8008
WM115 GDSC1; GDSC2; CTRP2 2.8462 4.1873 2.8138 14.754
WM1552C GDSC1; GDSC2 2.9331 4.5659 2.3522 7.3719
RVH-421 GDSC1; GDSC2; CTRP2 2.9628 5.0145 2.7808 14.5037
WM983B CTRP2 3.0412 6.9014 2.1726 16.5858
WM793 GDSC1; GDSC2; CTRP2 3.0424 4.6474 2.9537 13.6419
WM1799 CTRP2 3.1371 5.6275 2.7788 13.994
HMCB CTRP2 3.264 5.987 2.782 13.6218
SK-MEL-24 GDSC1; GDSC2; CTRP2 3.642 5.8392 3.2419 10.808
SK-MEL-28 GDSC1; GDSC2; CTRP2; CTRP1 3.8907 6.2502 3.3956 10.5081
Hs 895.T CTRP2 4.3357 9.5202 2.1915 13.3971
WT2-iPS GDSC1; GDSC2; CTRP2 4.5504 8.2947 2.9912 9.6313
CJM [Human melanoma] CTRP2 5.0885 6.767 4.2195 3.3832
IGR-39 CTRP2 5.2458 8.4963 3.4833 6.1831
Hs 934.T CTRP2 5.5003 10.0155 2.9279 8.0472
Hs 839.T CTRP2 5.6568 7.5842 4.2415 2.3598
Hs 688(A).T CTRP2 5.8253 7.351 4.4586 1.3013
EquiPSC Line K2 GDSC1; GDSC2 1.6548 5.2772 0.7535 21.7551
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYAE-1 GDSC1; GDSC2 0.0608 1.4789 0.0526 32.767
ESO-51 GDSC1; GDSC2 0.1022 3.8524 -0.3499 34.4023
OACP4 C GDSC1; GDSC2 0.5589 2.0652 0.5349 27.8487
ESO-26 GDSC1; GDSC2 0.7514 2.1999 0.7252 25.9281
FLO-1 GDSC1; GDSC2 0.9874 3.1739 0.813 24.336
SK-GT-4 GDSC1; GDSC2 1.4437 4.0415 1.0387 21.0407
TE-12 GDSC1; GDSC2 1.6493 5.9761 0.4322 23.5299
KYSE-50 GDSC1; GDSC2 1.8097 3.1178 1.7225 15.6286
KYSE-220 GDSC1; GDSC2 1.9816 3.6933 1.7432 14.7377
HCE-4 GDSC1; GDSC2 2.0554 5.9478 0.8467 19.6586
OACM5.1 C GDSC1; GDSC2 2.7377 4.6767 2.1122 9.5463
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 1.8933 4.7786 1.6742 21.7523
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-32 CTRP2 -1.7308 2.5885 -1.8522 45.3507
NB69 GDSC1; GDSC2 -1.0245 1.1649 -1.0496 43.7084
SJNB-14 GDSC1; GDSC2 -0.8626 1.1702 -0.8825 42.0744
CHP-212 GDSC1; GDSC2; CTRP2 -0.5807 1.802 -0.5928 37.5144
TGW GDSC1; GDSC2 -0.1251 1.0301 -0.1266 34.5984
GOTO GDSC1; GDSC2 0.0728 2.5455 -0.0461 33.1888
SJNB-7 GDSC1; GDSC2 0.1202 4.5235 -0.5609 35.1595
Kelly GDSC1; GDSC2; CTRP2 0.2111 1.3231 0.2111 32.2002
CHP-134 GDSC2 0.3306 2.2141 0.2798 30.2743
MHH-NB-11 GDSC1; GDSC2; CTRP2 0.4137 2.4638 0.4007 30.8938
SK-N-DZ GDSC1; GDSC2; CTRP2 0.4234 1.8754 0.4222 30.7897
CHP-126 GDSC1; GDSC2; CTRP2 0.4615 1.6742 0.4612 30.5327
SiMa GDSC1; GDSC2; CTRP2 0.4776 2.8399 0.4472 30.5262
SK-N-MC-IXC GDSC1; GDSC2 0.5245 1.451 0.5234 28.0782
SJNB-5 GDSC1; GDSC2 0.5248 2.4796 0.4512 28.4437
SJNB-17 GDSC1; GDSC2 0.5392 1.6257 0.5357 27.9424
SJNB-10 GDSC1; GDSC2 0.6759 2.3742 0.6271 26.8016
NH-12 GDSC1; GDSC2 0.692 3.2341 0.4753 27.5097
SK-N-BE(2) CTRP2 0.8499 3.9932 0.705 28.4343
NH-6 CTRP2 0.9263 2.7861 0.9134 27.4784
SJNB-6 GDSC1; GDSC2 0.936 2.1147 0.9236 24.0058
SJNB-13 GDSC1; GDSC2 0.9745 1.7322 0.9737 23.5606
KP-N-RT-BM-1 GDSC2 0.9784 4.0684 0.5276 25.8975
KP-N-SI9s CTRP2 1.0098 2.6578 1.0029 26.9022
SK-N-BE(2)-M17 GDSC1; GDSC2 1.0458 1.8886 1.0438 22.8509
SJNB-12 GDSC1; GDSC2 1.1251 4.6564 0.463 25.5799
IMR-5 GDSC1; GDSC2 1.1391 2.3894 1.1151 22.0266
KP-N-YS GDSC1; GDSC2 1.1659 3.111 1.023 22.3807
SK-N-AS GDSC1; GDSC2; CTRP2 1.2468 4.796 0.9651 26.269
SK-N-SH GDSC1; GDSC2; CTRP2 1.3051 4.4616 1.1067 25.5919
NB(TU)1 GDSC1; GDSC2 1.3523 2.6247 1.3149 19.956
SK-N-FI GDSC1; GDSC2; CTRP2 1.4266 3.0213 1.4168 24.1349
NB1 GDSC1; GDSC2; CTRP2 1.5156 3.4235 1.4862 23.6081
GI-ME-N GDSC1; GDSC2 1.9391 5.9567 0.7285 20.7713
LA-N-6 GDSC1; GDSC2 2.3404 5.0003 1.5704 14.3105
KP-N-YN GDSC1; GDSC2; CTRP2 5.8817 11.3292 2.5696 8.8666
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 -2.3102 2.1449 -2.4153 49.046
SNU-245 CTRP2 1.2818 4.6906 1.0291 25.9358
SNU-478 CTRP2 1.3334 3.0791 1.3186 24.7726
HuCC-T1 GDSC1; GDSC2; CTRP2 1.7518 4.7416 1.529 22.7065
HuH-28 CTRP2 1.8703 4.0514 1.7924 21.4108
SNU-1196 CTRP2 2.0259 3.7049 1.9971 20.2065
SNU-308 CTRP2 3.4436 5.7184 3.0761 11.9967
SNU-869 CTRP2 3.5904 5.9015 3.1625 11.256
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2157 GDSC1; GDSC2 -0.9541 0.6019 -0.9575 38.8883
HCC1599 GDSC2 0.2964 2.644 0.1774 28.0556
MDA-MB-453 GDSC1; GDSC2; CTRP2 0.3388 1.7492 0.338 31.3519
DU4475 GDSC1; GDSC2; CTRP2 0.3651 2.4052 0.3532 31.2137
HCC1428 GDSC1; GDSC2; CTRP2 0.3722 2.2517 0.3649 31.1512
CAL-148 GDSC2; CTRP2 0.7639 2.2533 0.7615 28.5251
EFM-19 GDSC1; GDSC2 0.7639 2.9463 0.6231 23.9154
EFM-192A GDSC1; GDSC2; CTRP2 0.8991 4.1817 0.7235 28.2119
HCC2218 GDSC1; GDSC2; CTRP2 0.9409 3.5851 0.8639 27.5975
Evsa-T GDSC1; GDSC2 0.9425 2.5487 0.8881 21.8831
MDA-MB-361 GDSC1; GDSC2; CTRP2 0.9912 3.7066 0.9015 27.3063
HCC1187 GDSC1; GDSC2 1.0874 9.4304 -1.7484 32.2851
MCF-7 GDSC1; GDSC2; CTRP2; CTRP1 1.0876 4.468 0.8898 27.8267
SK-BR-3 CTRP2 1.1699 2.5481 1.1673 25.8209
MDA-MB-330 GDSC1; GDSC2 1.1821 4.0856 0.7412 21.6086
AU565 GDSC1; GDSC2; CTRP2 1.1832 2.6772 1.1786 25.7392
OCUB-M GDSC1; GDSC2 1.495 3.3716 1.3144 17.4723
HCC1500 GDSC1; GDSC2; CTRP2 1.6149 4.3585 1.4641 23.3645
CAMA-1 GDSC1; GDSC2; CTRP2 1.6726 3.8321 1.6109 22.6721
CAL-51 GDSC1; GDSC2; CTRP2 1.7243 4.0375 1.6381 22.4118
BT-474 GDSC1; GDSC2; CTRP2 1.7366 3.6149 1.7016 22.1548
HCC1569 GDSC1; GDSC2 1.7471 4.2011 1.303 16.5325
Hs 578T GDSC1; GDSC2; CTRP2 1.7756 4.2475 1.6588 22.1763
HCC1143 GDSC1; GDSC2; CTRP2 1.8104 4.0775 1.7243 21.8383
MDA-MB-175-VII GDSC1; GDSC2 1.8175 4.09 1.4212 15.6487
UACC-812 GDSC2 1.836 4.4426 1.2997 16.2162
MDA-MB-231 GDSC1; GDSC2; CTRP2 1.906 3.7097 1.8709 21.0266
MFM-223 GDSC1; GDSC2 1.9097 3.1717 1.8189 13.2674
COLO 824 GDSC1; GDSC2 1.9341 4.5863 1.3418 15.6317
T-47D GDSC1; GDSC2; CTRP2 1.9764 3.8637 1.9294 20.5982
HCC70 GDSC1; GDSC2 2.0483 4.0912 1.6662 13.492
CAL-120 GDSC1; GDSC2; CTRP2 2.1329 4.2883 2.0369 19.7243
HCC1806 GDSC1; GDSC2; CTRP2 2.1632 4.827 1.9567 19.9116
MDA-MB-157 GDSC1; GDSC2; CTRP2 2.1787 4.9203 1.95 19.8876
HCC1419 GDSC1; GDSC2; CTRP2 2.2265 4.3298 2.1306 19.1006
HMC-1-8 CTRP2 2.2916 3.4654 2.2854 18.3601
CAL-85-1 GDSC1; GDSC2; CTRP2 2.4688 5.462 2.1094 18.4338
JIMT-1 GDSC1; GDSC2; CTRP2 2.5233 3.9481 2.4973 16.8836
UACC-893 GDSC1; GDSC2 2.5496 5.2199 1.6717 11.7148
MDA-MB-415 GDSC1; GDSC2 2.5848 4.7875 1.9109 10.2694
MDA-MB-436 GDSC1; GDSC2 2.7328 5.5748 1.6734 11.1268
HDQ-P1 GDSC1; GDSC2 2.7467 4.9276 2.0007 9.2426
HCC202 GDSC1; GDSC2; CTRP2 2.8033 5.0461 2.5982 15.6479
BT-483 GDSC1; GDSC2 2.8723 6.192 1.4969 11.7028
HCC1954 GDSC1; GDSC2; CTRP2 2.9094 5.0202 2.721 14.8817
MDA-MB-468 GDSC1; GDSC2; CTRP2 2.9975 5.7645 2.5794 15.1442
ZR-75-30 GDSC1; GDSC2; CTRP2 3.0457 5.8507 2.5999 14.9294
MRK-nu-1 GDSC1; GDSC2 3.2203 6.6754 1.5598 10.3641
BT-20 GDSC1; GDSC2; CTRP2 3.3686 6.0075 2.8852 12.9356
HCC1395 GDSC1; GDSC2; CTRP2 3.4122 5.8307 3.0002 12.3739
BT-549 GDSC1; GDSC2; CTRP2 3.4784 6.4601 2.8148 12.9105
ZR-75-1 CTRP2 3.5322 6.3127 2.9332 12.3037
HCC38 GDSC1; GDSC2; CTRP2 3.7003 5.8833 3.2862 10.4767
HCC1937 GDSC1; GDSC2; CTRP2 4.0713 7.924 2.7306 11.7788
YMB-1-E GDSC2 4.0885 7.973 1.6002 8.824
Hs 578Bst CTRP2 5.1822 6.8738 4.2418 3.1167
BT 428 CTRP2 0.2829 6.4172 -0.5825 34.3596
BT 416 CTRP2 0.936 2.7973 0.9228 27.4149
BT 245 CTRP2 1.9665 4.3768 1.8413 20.9345
BT 145 CTRP2 2.1811 4.655 2.0167 19.643
BT 216 CTRP2 2.3903 8.9276 0.6093 24.1804
BT 187 CTRP2 2.854 7.6393 1.6583 19.0754
BT 333 CTRP2 3.0312 5.5615 2.6871 14.6436
BT 179 CTRP2 3.1822 4.6808 3.0986 12.6933
BT 172 CTRP2 3.2458 7.5462 2.0977 16.3448
BT 224 CTRP2 3.3517 5.9039 2.9076 12.8967
BT 286 CTRP2 3.44 9.8989 1.1779 19.4356
BT 330 CTRP2 3.5272 8.6963 1.8391 16.6685
BT 159 CTRP2 3.5844 7.4853 2.4648 14.0288
BT164 CTRP2 3.7195 6.5059 3.0439 11.3733
BT 139 CTRP2 3.9326 7.4362 2.8306 11.6979
BT 320 CTRP2 4.0012 5.7308 3.6657 8.1855
BT 112 CTRP2 4.0454 7.7582 2.7858 11.6132
BT 359 CTRP2 4.0455 8.2104 2.5675 12.5066
BT 231 CTRP2 4.2129 11.4586 1.1204 17.8761
BT 248 CTRP2 4.2493 8.9953 2.3727 12.8453
BT 504 CTRP2 4.2557 7.1683 3.2703 9.1333
BT 232 CTRP2 4.3675 6.9661 3.4741 8.0347
BT147 CTRP2 4.5069 7.2552 3.4644 7.7571
BT 239 CTRP2 4.577 10.3303 2.0025 13.6504
BT 131 CTRP2 4.7964 8.7318 2.9901 9.1225
BT 340 CTRP2 5.099 7.6645 3.7795 5.2122
BT 444 CTRP2 5.1459 8.0836 3.6086 5.842
BT 498 CTRP2 5.1852 7.2512 4.056 3.8905
BT 422 CTRP2 5.2599 15.1602 0.1649 19.0922
BT 271 CTRP2 5.5197 9.7261 3.0869 7.3514
BT 228 CTRP2 5.6526 13.0249 1.549 13.3484
BT 440 CTRP2 5.7779 7.7014 4.2661 2.0969
BT 328 CTRP2 5.9739 9.6581 3.4588 5.0694
BT 482 CTRP2 6.7225 21.2367 -1.6993 21.8835
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 2.5584 4.0083 2.5285 16.6628
Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med GDSC1; GDSC2; CTRP2 -0.3388 0.9401 -0.3389 35.8639
D-423MG GDSC1; GDSC2 -0.0364 2.1829 -0.1066 34.0448
D-566MG GDSC1; GDSC2 0 1.7393 -0.0234 33.4524
PFSK-1 GDSC1; GDSC2 0.5098 2.5335 0.4267 28.6426
MOG-G-UVW GDSC1; GDSC2 0.8445 3.1684 0.6586 25.8263
H4 GDSC1; GDSC2 0.9023 3.0558 0.749 25.0758
Daoy GDSC1; GDSC2; CTRP2 1.2356 3.4194 1.1934 25.5168
SNU-201 CTRP2 1.4149 4.9644 1.105 25.2525
GI-1 GDSC1; GDSC2 1.4823 3.2006 1.3461 19.1735
AM-38 GDSC1; GDSC2 1.4837 2.7569 1.4371 18.6851
GB-1 GDSC1; GDSC2; CTRP2 1.5199 3.7627 1.4573 23.6923
SK-MG-1 GDSC1; GDSC2 1.5336 3.5429 1.3057 19.1593
SNU-466 CTRP2 1.6379 2.3587 1.6379 22.6943
SF268 GDSC1; GDSC2; CTRP2 1.6821 3.3666 1.6632 22.4634
LNZTA3WT4 GDSC1 1.7291 3.5582 1.5138 21.3384
MOG-G-CCM GDSC1; GDSC2 1.7586 3.6192 1.5263 16.9334
D-245MG GDSC2 1.7906 5.1856 0.9327 20.1952
ONS-76 GDSC1; GDSC2; CTRP2 1.8474 4.2885 1.729 21.7035
SF295 GDSC1; GDSC2; CTRP2; CTRP1 1.9443 3.5293 1.9288 21.5677
M059K CTRP2 1.9642 4.2669 1.8588 20.8807
D-263MG GDSC1; GDSC2 1.9916 4.2931 1.5247 15.949
LN-18 GDSC1; GDSC2; CTRP2 2.2107 3.6878 2.1911 18.9441
A-172 GDSC1; GDSC2; CTRP2 2.2502 4.6214 2.0992 19.1359
SF126 GDSC1; GDSC2; CTRP2 2.2865 3.9928 2.2432 18.5197
M059J GDSC1; GDSC2 2.3725 4.5406 1.8124 12.7305
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 2.4365 4.7535 1.7799 12.6825
SNU-1105 CTRP2 2.4671 4.3766 2.3818 17.4615
KG-1-C CTRP2 2.4923 4.4246 2.4007 17.3156
SF539 GDSC1; GDSC2; CTRP2 2.5439 6.1951 1.9332 18.8726
YKG-1 GDSC1; GDSC2; CTRP2 2.5573 5.2076 2.2839 17.5315
SNU-738 CTRP2 2.5806 5.4439 2.2368 17.6342
Becker GDSC1; GDSC2; CTRP2 2.5876 4.4598 2.4972 16.6766
U-251MG GDSC1; GDSC2; CTRP2 2.6188 4.7248 2.4772 16.6487
Hs 683 GDSC1; GDSC2; CTRP2 2.6307 4.8461 2.4617 16.6669
42-MG-BA GDSC1; GDSC2; CTRP2 2.6777 4.6922 2.5485 16.2127
GaMG GDSC1; GDSC2; CTRP2; CTRP1 2.6829 4.8929 2.5317 17.1659
D-502MG GDSC1; GDSC2 2.6948 5.8114 1.5225 13.3381
U-118MG GDSC1; GDSC2; CTRP2 2.6957 5.9772 2.1773 17.521
TM-31 CTRP2 2.6962 4.4498 2.6162 15.9173
KINGS-1 GDSC1; GDSC2 2.7074 4.9128 1.9703 10.5286
SNU-626 CTRP2 2.7484 4.9558 2.5623 15.9448
YH-13 GDSC1; GDSC2; CTRP2 2.7647 5.5505 2.4019 16.4819
D-247MG GDSC1; GDSC2 2.7859 5.5719 1.7241 11.7837
SNU-489 CTRP2 2.9291 5.9769 2.4279 15.9111
CAS-1 GDSC1; GDSC2 2.9484 4.5872 2.3563 7.2942
LN-229 GDSC1; GDSC2; CTRP2; CTRP1 2.9544 6.3552 2.3625 16.9932
Onda 10 GDSC1; GDSC2 3.009 4.9834 2.2179 7.9563
LN-405 GDSC1; GDSC2 3.0189 5.5688 1.9369 9.6889
DK-MG GDSC1; GDSC2; CTRP2 3.0666 5.9046 2.6023 14.8611
D-392MG GDSC1; GDSC2 3.0683 4.7574 2.3832 6.7244
D-336MG GDSC1; GDSC2 3.1314 4.5317 2.5518 5.4601
SW1088 GDSC1; GDSC2; CTRP2 3.1577 5.2702 2.9196 13.4115
U-87MG ATCC GDSC1; GDSC2; CTRP2 3.2423 5.626 2.893 13.2627
T98G GDSC1; GDSC2; CTRP2 3.2483 5.1333 3.0593 12.6302
KNS-81-FD GDSC1; GDSC2 3.4285 5.9633 2.0889 7.5006
DBTRG-05MG GDSC1; GDSC2; CTRP2 3.4318 5.9872 2.9604 12.4715
KALS-1 GDSC1; GDSC2; CTRP2 3.4846 7.3495 2.4274 14.4291
GOS-3 CTRP2 3.6166 6.7149 2.8465 12.4226
Onda 11 GDSC1; GDSC2 3.6292 7.3555 1.5551 10.2848
SNB-75 GDSC1; GDSC2; CTRP2 3.7166 7.5916 2.5461 13.3755
D-542MG GDSC1; GDSC2 4.0447 8.1636 1.4739 9.6973
NMC-G1 GDSC1; GDSC2; CTRP2 4.0836 6.5722 3.383 9.0897
GMS-10 CTRP2 4.1027 6.3876 3.4864 8.6265
8-MG-BA GDSC1; GDSC2; CTRP2 4.1935 5.9952 3.7543 7.3256
SW1783 GDSC1; GDSC2; CTRP2 4.6861 9.1137 2.7039 10.5428
KNS-42 GDSC1; GDSC2; CTRP2 4.9958 7.8733 3.5893 6.2107
CCF-STTG1 CTRP2 5.502 7.4643 4.1913 2.7931
⏷ Show the Full List of 67 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 1.6818 3.1583 1.5739 17.0216
ETK-1 GDSC1; GDSC2 2.1766 5.7069 1.0787 17.8593
TGBC1TKB GDSC1; GDSC2 2.7761 4.3785 2.2905 8.3125
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-6 CTRP2; CTRP1 -0.1549 2.2597 -0.1715 35.4032
MFE-319 GDSC1; GDSC2; CTRP2; CTRP1 0.4043 2.6086 0.3877 31.7192
JHUEM-2 CTRP2; CTRP1 0.5755 6.0886 -0.1125 32.7123
RL95-2 GDSC1; GDSC2; CTRP2 1.1096 2.6462 1.1046 26.231
HEC-59 CTRP2; CTRP1 1.3494 3.7981 1.2817 25.6626
HEC-1-A CTRP2 1.5078 3.8665 1.431 23.8214
HEC-151 CTRP2; CTRP1 1.9295 3.7759 1.8963 21.7242
KLE GDSC1; GDSC2; CTRP2; CTRP1 2.0846 5.3977 1.746 21.7665
HEC-1-B CTRP2 2.0961 3.8153 2.0608 19.7609
HEC-265 CTRP2; CTRP1 2.1285 3.6592 2.112 20.3571
JHUEM-3 CTRP2 2.1773 4.0253 2.1234 19.2834
ESS-1 GDSC1; GDSC2; CTRP2 2.3868 4.8722 2.1892 18.3923
HEC-108 CTRP2; CTRP1 2.3945 4.5135 2.2956 18.8837
HEC-251 CTRP2; CTRP1 2.419 5.7669 1.9955 19.8772
MFE-280 GDSC1; GDSC2 2.4333 4.397 1.9383 11.7405
EN GDSC1; GDSC2; CTRP2 2.8141 5.813 2.3643 16.479
JHUEM-1 CTRP2 2.8188 4.3602 2.7624 15.0187
MFE-296 GDSC1; GDSC2; CTRP2 2.8245 6.1782 2.2395 16.9211
AN3-CA GDSC1; GDSC2; CTRP2 2.8438 5.1561 2.6114 15.4773
EFE-184 CTRP2 3.1316 5.6717 2.7573 14.0903
JHUEM-7 CTRP2 3.3472 5.5125 3.0461 12.3865
HEC-50B CTRP2 4.6937 7.3418 3.5918 6.8182
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 -0.09 1.8326 -0.0941 34.9353
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB1047-RCC GDSC1; GDSC2 0.6081 2.0224 0.5893 27.3284
CAL-54 GDSC1; GDSC2; CTRP2 0.9089 5.2059 0.4861 28.9856
KTCTL-21 GDSC1; GDSC2 1.19 7.0804 -0.5349 30.0071
KTCTL-140 GDSC1; GDSC2 1.3746 3.4163 1.1702 20.6221
LB2241-RCC GDSC1; GDSC2 1.4875 3.8949 1.1386 20.2916
SW13 GDSC1; GDSC2 1.5942 2.8985 1.5328 17.654
KTCTL-195 GDSC1; GDSC2 1.6322 4.2272 1.1706 19.4871
TUHR14TKB CTRP2 1.67 5.4593 1.2407 23.9859
KTCTL-13 GDSC1; GDSC2 1.7147 3.3428 1.5622 16.9327
TUHR4TKB CTRP2 1.7372 4.5791 1.5508 22.6754
A-498 GDSC1; GDSC2 1.7616 3.8251 1.4593 17.2948
RXF 393L GDSC1; GDSC2 1.8309 4.0508 1.4505 17.0474
BB65-RCC GDSC1; GDSC2 1.8411 3.9699 1.492 16.7674
NCC021 GDSC1; GDSC2 1.8561 4.2413 1.4028 17.2157
TK-10 GDSC1; GDSC2 2.0655 4.1549 1.6588 14.8643
SN12C GDSC1; GDSC2 2.0674 4.4994 1.5172 15.6852
KTCTL-1M GDSC1; GDSC2 2.0796 3.9639 1.7494 14.282
VMRC-RCW GDSC1; GDSC2; CTRP2; CTRP1 2.1281 4.461 2.0174 20.6793
SW156 GDSC1; GDSC2 2.1432 4.8094 1.4592 15.729
KTCTL-26A GDSC1; GDSC2 2.1798 3.595 1.9914 12.4755
769-P GDSC1; GDSC2; CTRP2 2.2084 4.0438 2.1542 19.0773
BFTC-909 GDSC1; GDSC2; CTRP2 2.2449 4.3826 2.1411 19.0057
A-704 GDSC1; GDSC2 2.274 4.4136 1.7677 13.382
NCC010 GDSC1; GDSC2 2.353 4.9679 1.598 14.0965
UO-31 GDSC1; GDSC2; CTRP2 2.5199 4.8985 2.3277 17.4871
VMRC-RCZ GDSC1; GDSC2; CTRP2 2.5203 4.0383 2.4854 16.9338
Caki-1 GDSC1; GDSC2; CTRP2 2.6012 5.5053 2.2393 17.5641
KMRC-20 GDSC1; GDSC2; CTRP2 2.6527 4.9597 2.4569 16.6162
HA7-RCC GDSC1; GDSC2 2.6666 4.6286 2.0657 10.0889
ACHN GDSC1; GDSC2; CTRP2 2.7685 4.7293 2.6391 15.6089
LB996-RCC GDSC2 2.7996 4.8971 2.0657 9.6148
SNU-1272 CTRP2 2.8039 7.2698 1.7686 18.7843
786-O GDSC1; GDSC2; CTRP2 2.8521 5.0433 2.6522 15.3044
OS-RC-2 GDSC1; GDSC2; CTRP2 3.0117 6.4453 2.3323 16.0466
KMRC-3 CTRP2 3.1114 7.3739 2.0387 16.9239
Caki-2 CTRP2 3.1147 5.7021 2.7282 14.2485
RCC10RGB GDSC1; GDSC2; CTRP2; CTRP1 3.1183 5.9362 2.6945 15.2909
TUHR10TKB CTRP2 3.3115 4.1983 3.3006 11.5815
KMRC-1 GDSC1; GDSC2; CTRP2 3.446 5.4785 3.1648 11.6563
KMRC-2 CTRP2 4.0572 8.9283 2.2288 13.8626
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 63 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 320HSR GDSC1; GDSC2 0.0884 1.7893 0.065 32.5655
DiFi GDSC1; GDSC2 0.1206 1.8077 0.0972 32.2426
NCI-H508 GDSC1; GDSC2; CTRP2; CTRP1 0.1292 2.2538 0.1192 33.5101
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2; CTRP1 0.3034 1.5851 0.3032 32.3301
HCT 116 GDSC1; GDSC2; CTRP2; CTRP1 0.3383 2.5334 0.3232 32.1491
CL-34 CTRP1 0.366 2.4964 0.353 67.8628
LoVo GDSC1; GDSC2; CTRP2; CTRP1 0.4675 2.4713 0.4575 31.281
COLO 320 CTRP2; CTRP1 0.6394 5.1011 0.2215 30.7374
COLO205 GDSC1; GDSC2; CTRP2; CTRP1 0.6892 1.832 0.689 29.7877
CCK-81 GDSC1; GDSC2; CTRP2 0.7726 2.7693 0.7562 28.5141
SW948 GDSC1; GDSC2; CTRP2; CTRP1 0.8392 2.3716 0.8366 28.8071
SNU-175 GDSC2; CTRP2; CTRP1 0.9402 2.7028 0.9324 28.1587
HT115 GDSC1; GDSC2; CTRP2; CTRP1 0.9483 2.4726 0.9453 28.0897
SW626 GDSC1; GDSC2 0.9563 2.9484 0.8318 24.3831
LS411N GDSC1; GDSC2; CTRP2; CTRP1 1.0129 2.8075 1.0034 27.6853
CW-2 GDSC1; GDSC2; CTRP2; CTRP1 1.0232 3.5671 0.9626 27.7878
C2BBe1 GDSC1; GDSC2; CTRP2; CTRP1 1.0912 2.7645 1.0844 27.1606
HT-55 GDSC1; GDSC2; CTRP2; CTRP1 1.13 2.6539 1.1261 26.8951
SNU-C5 GDSC1; GDSC2; CTRP2; CTRP1 1.1435 3.9433 1.0428 27.1303
SW48 GDSC1; GDSC2; CTRP2; CTRP1 1.1903 2.7129 1.1861 26.4987
GP2d CTRP2; CTRP1 1.2515 2.9654 1.2418 26.114
HCT 8 CTRP2; CTRP1 1.4137 2.9332 1.408 25.0314
CL-11 GDSC1; GDSC2; CTRP2 1.4375 3.2738 1.4155 24.1036
OUMS-23 CTRP2 1.46 2.3832 1.4598 23.8806
CaR-1 GDSC1; GDSC2 1.4766 3.54 1.2445 19.7528
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 1.4985 2.8392 1.4957 24.463
SNU-1033 CTRP2 1.5456 3.303 1.5257 23.3763
LS513 GDSC1; CTRP2; CTRP1 1.6363 3.6091 1.6033 23.6557
SW1463 GDSC1; GDSC2; CTRP2 1.6389 3.7901 1.5803 22.8859
SNU-C1 GDSC1; GDSC2; CTRP2 1.6491 3.0287 1.6434 22.639
LS123 GDSC1; GDSC2; CTRP2; CTRP1 1.7328 4.0915 1.6518 23.182
T84 GDSC1; GDSC2; CTRP2 1.7383 3.6524 1.6999 22.155
SNU-1040 CTRP1 1.7503 3.9511 1.6888 49.4513
LS180 GDSC1; GDSC2; CTRP2; CTRP1 1.7552 3.272 1.746 22.7926
NCI-H747 GDSC1; GDSC2; CTRP2 1.7623 3.6373 1.7266 21.9862
COLO201 CTRP2 1.9021 2.5626 1.9021 20.9345
SNU-61 GDSC1; GDSC2; CTRP2; CTRP1 1.9074 3.8484 1.8663 21.8963
SW620 GDSC1; GDSC2; CTRP2; CTRP1 1.909 3.6767 1.8828 21.8361
SNU-C2A CTRP2; CTRP1 1.9433 5.3068 1.6179 22.6478
DLD-1 CTRP2; CTRP1 1.9787 3.9014 1.9361 21.4317
SW480 CTRP1 1.9998 4.4406 1.8827 46.1956
SW1116 GDSC1; GDSC2 2.0362 3.4734 1.8747 13.7628
HT-29 GDSC1; GDSC2; CTRP2; CTRP1 2.0587 4.8039 1.8726 21.3982
SNU-407 GDSC1; GDSC2; CTRP2 2.0678 4.5963 1.9064 20.3866
SK-CO-1 GDSC1; GDSC2; CTRP2; CTRP1 2.0685 3.9717 2.0236 20.8475
GP5d GDSC1; GDSC2 2.1018 3.6209 1.8982 13.3402
SNU-C2B GDSC1; GDSC2 2.1684 5.1323 1.3382 16.3523
SW837 GDSC1; GDSC2 2.1828 3.869 1.8959 13.0044
KM12 GDSC1; GDSC2; CTRP2; CTRP1 2.2117 4.4418 2.111 20.0941
SNU-503 CTRP2 2.2897 5.3028 1.9638 19.5009
SNU-81 GDSC1; GDSC2; CTRP1 2.3061 4.3568 2.2264 24.8388
HCC-56 CTRP2 2.4167 3.536 2.4109 17.5254
RKO GDSC1; GDSC2; CTRP2; CTRP1 2.5493 5.4312 2.2429 18.5973
SNU-283 GDSC2 2.5906 3.8285 2.3451 8.7037
HCT 15 GDSC1; GDSC2; CTRP2 2.5927 4.5068 2.4941 16.6712
SW1417 GDSC1; GDSC2; CTRP2 2.6782 3.9151 2.6616 15.8195
CL-40 CTRP1 2.68 4.5737 2.5929 36.7044
HCC2998 GDSC1; GDSC2 2.7123 5.1896 1.8416 11.3065
COLO 678 GDSC1; GDSC2; CTRP2; CTRP1 2.9143 5.3768 2.6571 16.0203
NCI-H716 GDSC1; GDSC2; CTRP2 2.9354 6.3976 2.271 16.4923
SNU-C4 CTRP2; CTRP1 3.0837 4.7198 3.0026 14.2826
LS1034 GDSC1; GDSC2; CTRP2 3.1007 4.268 3.074 13.0394
SW403 CTRP1 3.6803 6.6073 3.0257 26.7779
⏷ Show the Full List of 63 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 0.3977 3.3039 0.1355 30.6609
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 GDSC1; GDSC2; CTRP2 -0.2367 0.9293 -0.2367 35.1835
SNU-182 CTRP2 0.0728 3.8252 -0.1036 33.6927
Hep-G2 CTRP2; CTRP1 0.5503 3.5712 0.4605 30.9989
HuH-6 CTRP2 0.7299 3.2854 0.6743 60.5529
Huh-7 GDSC1; GDSC2 1.345 3.048 1.2326 20.423
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 1.4517 3.4599 1.4165 24.0537
HLE GDSC1; GDSC2 1.5382 6.348 0.15 25.4345
Li-7 CTRP2 1.9117 5.9542 1.3401 22.9027
JHH-5 CTRP2 1.932 4.7561 1.7219 21.4629
SNU-398 GDSC1; GDSC2; CTRP1 2.0301 5.4753 1.6636 28.4083
JHH-7 GDSC1; GDSC2 2.0855 3.5626 1.9 13.4024
JHH-2 GDSC1; GDSC2; CTRP2 2.1022 4.3546 1.9922 19.9775
HuH-1 GDSC1; GDSC2; CTRP2 2.139 3.8926 2.0982 19.494
JHH-4 GDSC1; GDSC2; CTRP2 2.1721 3.7322 2.1476 19.2179
SNU-886 CTRP2 2.2375 3.9752 2.1933 18.849
SNU-423 GDSC1; GDSC2; CTRP2 2.4159 4.4524 2.3131 17.8633
Hep-G2/C3A GDSC1; GDSC2 2.5143 3.9875 2.1993 9.869
SNU-449 GDSC1; GDSC2; CTRP2; CTRP1 2.6272 5.2393 2.3832 17.8611
SNU-387 GDSC1; GDSC2; CTRP2 2.6447 4.7653 2.4962 16.5008
PLC/PRF/5 CTRP2 2.7594 4.183 2.7224 15.3479
SK-HEP-1 GDSC1; GDSC2; CTRP2 2.9087 5.1222 2.6919 14.9892
HLF CTRP2 2.9956 4.2418 2.9658 13.7497
JHH-6 GDSC1; GDSC2; CTRP2; CTRP1 5.1287 7.6954 3.8986 5.6061
SNU-475 CTRP2 5.5813 8.4043 3.7882 4.3298
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 226 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COR-L51 CTRP1 -3.1625 -0.1682 -3.1684 93.9782
SCLC-21H CTRP1 -2.579 0.2422 -2.5849 92.1086
DMS 454 CTRP2 -1.3276 4.8106 -5.5703 15.9442
HCC33 GDSC2; CTRP1 -0.6318 0.7709 -0.6319 49.2829
NCI-H290 GDSC1; GDSC2 -0.6002 1.5691 -0.6367 39.5221
LC-1/sq GDSC1; GDSC2 -0.42 2.053 -0.4982 37.9051
LB647-SCLC GDSC1; GDSC2 -0.3096 1.8138 -0.3537 36.6529
COR-L321 GDSC1; GDSC2 -0.3045 0.9908 -0.307 36.4036
NCI-H524 GDSC1; GDSC2 -0.2876 1.1252 -0.2923 36.2454
NCI-H1105 GDSC1; GDSC2; CTRP2; CTRP1 -0.2816 0.9918 -0.2817 36.1849
NCI-H209 GDSC1; GDSC2 -0.264 1.586 -0.2875 36.0992
NCI-H146 GDSC1; GDSC2; CTRP2 -0.1701 1.1534 -0.1704 34.7407
MOR/CPR CTRP2 -0.166 0.9297 -0.166 34.7123
NCI-H2171 GDSC2; CTRP2 -0.1494 1.0184 -0.1494 34.6019
SBC-3 GDSC1; GDSC2 -0.1152 2.2894 -0.206 34.929
Lu-139 GDSC1 -0.0209 1.8364 -0.0527 41.9434
NCI-H2009 GDSC1; GDSC2; CTRP2; CTRP1 0.0128 2.1718 0.003 34.2764
NCI-H250 GDSC2 0.0452 1.6969 0.0262 32.9772
EMC-BAC-1 GDSC1; GDSC2 0.0512 2.8424 -0.1289 33.6922
COR-L303 GDSC2 0.0709 1.6336 0.0563 32.6978
NCI-H64 GDSC1; GDSC2 0.0941 1.1819 0.0926 32.399
NCI-H1963 GDSC1; GDSC2; CTRP1 0.1114 1.4542 0.1111 43.0133
NCI-H1694 GDSC1; GDSC2; CTRP2; CTRP1 0.1346 1.5297 0.1341 33.4433
A-427 GDSC1; GDSC2 0.1677 2.9888 -0.0354 32.6487
NCI-H211 GDSC1; GDSC2; CTRP2 0.1806 1.1391 0.1806 32.4033
NCI-H810 GDSC1; GDSC2; CTRP2; CTRP1 0.1908 1.6149 0.1903 33.073
Ms-1 GDSC1; GDSC2 0.2225 1.6933 0.2096 31.1681
Sq-1 CTRP1 0.2959 2.5354 0.2796 68.5427
NCI-H1341 GDSC1; GDSC2; CTRP2 0.3278 1.5496 0.3276 31.4234
IST-SL2 GDSC1; GDSC2 0.3443 2.4176 0.2671 30.2704
NCI-H2106 CTRP2 0.3558 2.1925 0.3497 31.2566
NCI-H847 GDSC1; GDSC2 0.3744 1.1792 0.3741 29.5801
NCI-H187 GDSC1 0.3979 1.248 0.3975 36.5525
NCI-H2227 GDSC1; GDSC2 0.4006 1.9773 0.3765 29.4377
COR-L88 GDSC1; GDSC2; CTRP1 0.4405 1.9092 0.4394 40.24
CPC-N GDSC1; GDSC2 0.4616 1.5427 0.4587 28.7183
NCI-H1876 GDSC1; GDSC2; CTRP1 0.4633 2.4611 0.4535 40.0814
NCI-H2126 CTRP2; CTRP1 0.4678 2.2054 0.4639 31.2587
IST-SL1 GDSC1; GDSC2 0.5102 1.7309 0.5032 28.2515
COR-L311 GDSC2 0.5143 1.8209 0.5038 28.2276
DMS 273 GDSC1; GDSC2; CTRP2; CTRP1 0.5522 4.5792 0.284 31.567
SBC-1 GDSC1; GDSC2 0.5698 1.6642 0.5659 27.6374
NCI-H835 GDSC1; GDSC2 0.5918 1.6243 0.589 27.4113
NCI-H748 GDSC2 0.6254 1.9534 0.6116 27.1299
NCI-H510A GDSC1; GDSC2 0.627 2.3743 0.5751 27.3078
VMRC-LCD GDSC1; GDSC2; CTRP2; CTRP1 0.652 2.5843 0.6422 30.0646
NCI-H1770 GDSC1; GDSC2 0.6558 2.164 0.6281 26.8949
NCI-H526 GDSC1; GDSC2; CTRP2 0.6584 1.9303 0.6578 29.222
COR-L279 GDSC1; GDSC2; CTRP1 0.6688 2.2 0.6668 38.3177
NCI-H2081 GDSC1; GDSC2; CTRP2; CTRP1 0.6726 2.5308 0.6648 29.9221
NCI-H720 GDSC1; GDSC2 0.6952 3.5468 0.3909 27.9303
NCI-H1930 CTRP1 0.6987 1.3049 0.6987 64.4362
NCI-H345 GDSC1; GDSC2 0.7001 2.8105 0.5823 26.9149
NCI-H82 GDSC1; GDSC2; CTRP1 0.7554 2.6749 0.7448 37.6224
COR-L23 GDSC1; GDSC2; CTRP1 0.8013 2.8435 0.7853 37.2567
NCI-H69 GDSC1; GDSC2; CTRP2 0.8107 2.1621 0.8095 28.2094
COR-L32 GDSC2 0.8443 3.0239 0.6932 25.6453
NCI-H1734 GDSC1; GDSC2; CTRP2 0.8533 3.6454 0.7627 28.2273
NCI-H889 CTRP2 0.8638 2.56 0.857 27.8743
NCI-H1184 CTRP2 0.8738 2.8435 0.8568 27.842
HCC78 GDSC1; GDSC2; CTRP2; CTRP1 0.8841 3.2223 0.8482 28.622
LXF 289 GDSC1; GDSC2; CTRP2; CTRP1 0.9139 3.1888 0.8818 28.4128
Lu-134-A GDSC1; GDSC2 0.9212 2.6745 0.8461 24.4765
NCI-H446 GDSC1; GDSC2; CTRP2 0.9383 3.052 0.9117 27.4446
HCC1833 CTRP2; CTRP1 0.9954 4.6879 0.7417 28.6202
NCI-H1435 GDSC1; GDSC2; CTRP2; CTRP1 1.0105 2.7675 1.0022 27.6972
NCI-H23 GDSC1; GDSC2; CTRP2; CTRP1 1.0111 3.2653 0.9774 27.7776
HCC15 GDSC1; GDSC2; CTRP2; CTRP1 1.0304 3.7392 0.95 27.8068
NCI-H1437 GDSC1; GDSC2; CTRP1 1.0647 4.4894 0.8605 35.7655
EBC-1 GDSC1; GDSC2; CTRP2; CTRP1 1.0917 3.208 1.0653 27.2223
IA-LM GDSC1; GDSC2 1.0932 2.9912 0.9713 22.9979
SBC-5 GDSC1; GDSC2; CTRP2 1.0977 1.9684 1.0976 26.2939
A-549 GDSC1; GDSC2; CTRP2; CTRP1 1.1293 3.0895 1.1111 26.9471
HCC44 GDSC1; GDSC2; CTRP2; CTRP1 1.1566 4.1535 1.0236 27.1532
NCI-H1581 GDSC1; GDSC2; CTRP2 1.1743 1.7277 1.1743 25.7829
NCI-H1385 CTRP2 1.1818 4.5274 0.9581 26.4989
NCI-H2795 GDSC1; GDSC2 1.1974 3.4689 0.9616 22.5652
NCI-H1688 GDSC1; GDSC2 1.2046 3.2292 1.0359 22.1306
NCI-H1568 GDSC1; GDSC2; CTRP2; CTRP1 1.2517 4.3003 1.1002 26.5902
NCI-H2818 GDSC1; GDSC2 1.2617 3.3408 1.0683 21.692
NCI-H1436 GDSC1; GDSC2 1.2772 2.9714 1.1755 21.0458
EMC-BAC-2 GDSC1; GDSC2 1.2778 3.3432 1.0852 21.5268
NCI-H1836 GDSC1; GDSC2; CTRP1 1.289 3.5717 1.2423 33.2718
NCI-H1975 GDSC1; GDSC2; CTRP1 1.3227 3.2255 1.3034 32.8735
COLO 699 CTRP2; CTRP1 1.3504 4.9026 1.0776 26.3571
NCI-H1666 GDSC1; GDSC2; CTRP2; CTRP1 1.3599 5.0751 1.0442 26.4425
NCI-H740 GDSC2 1.3838 3.4554 1.1688 20.5875
NCI-H2369 GDSC1; GDSC2 1.4084 3.3693 1.2206 20.1931
NCI-H661 GDSC1; GDSC2; CTRP2; CTRP1 1.4119 2.8912 1.4072 25.0402
HOP-92 GDSC1; GDSC2; CTRP2 1.4514 4.3476 1.2891 24.4927
NCI-H2373 GDSC1; GDSC2 1.4557 3.1101 1.339 19.336
HCC827 GDSC1; GDSC2; CTRP2; CTRP1 1.4558 4.6187 1.2578 25.4069
Lu-135 GDSC1; GDSC2 1.4674 3.3148 1.3 19.4912
DV-90 CTRP2; CTRP1 1.496 3.9272 1.4214 24.7202
NCI-H1651 GDSC1; GDSC2 1.4998 3.1216 1.3843 18.8869
UMC-11 GDSC1; GDSC2 1.5159 2.4464 1.5041 18.1832
NCI-H1155 GDSC1; GDSC2; CTRP2 1.5215 3.035 1.5133 23.4976
NCI-H2073 CTRP1 1.5442 4.491 1.3802 52.037
NCI-H1092 GDSC1; GDSC2; CTRP2 1.5497 5.1118 1.2119 24.4572
RERF-LC-A1 CTRP2 1.6115 4.1385 1.5007 23.2482
LK-2 GDSC1; GDSC2 1.6177 2.4742 1.608 17.1508
Calu-3 GDSC1; GDSC2; CTRP2; CTRP1 1.6188 4.5893 1.4411 24.2645
NCI-H1048 GDSC1; GDSC2; CTRP1 1.6321 4.2569 1.5181 30.6645
NCI-H3122 GDSC1; GDSC2 1.641 3.8447 1.3222 18.592
NCI-H2122 GDSC1; GDSC2; CTRP2; CTRP1 1.6452 4.3257 1.5204 23.9085
NCI-H1915 GDSC1; GDSC2; CTRP2; CTRP1 1.6613 3.9198 1.5982 23.5923
ABC-1 GDSC1; GDSC2 1.6904 4.4575 1.1405 19.414
NCI-H1755 GDSC1; GDSC2; CTRP2; CTRP1 1.6956 4.0993 1.6109 23.4393
COLO 668 GDSC1; GDSC2; CTRP2; CTRP1 1.709 4.4102 1.5741 23.5229
HCC1588 CTRP2 1.7257 3.7459 1.6773 22.2729
LCLC-103H GDSC1; GDSC2; CTRP2; CTRP1 1.7286 3.1192 1.7234 22.955
NCI-H2804 GDSC1; GDSC2 1.734 4.3404 1.2339 18.6964
DMS 79 GDSC1; GDSC2 1.7485 2.8092 1.7127 15.9725
DMS 53 GDSC1; GDSC2; CTRP2 1.778 3.6968 1.7375 21.8979
NCI-H2170 GDSC1; GDSC2; CTRP2 1.8117 3.7077 1.7719 21.6706
PC-14 GDSC1; GDSC2 1.8209 3.3693 1.6706 15.8575
Lu-99 CTRP2; CTRP1 1.8316 5.5039 1.4387 23.6202
LCLC-97TM1 GDSC1; GDSC2; CTRP2; CTRP1 1.8438 4.0381 1.7774 22.4007
SW1573 GDSC1; GDSC2 1.8462 3.3654 1.6994 15.5847
LC-2/ad GDSC1; GDSC2 1.8483 3.1147 1.7652 15.2201
HCC2108 CTRP2; CTRP1 1.8501 3.912 1.7991 22.3073
NCI-H358 GDSC1; GDSC2; CTRP2; CTRP1 1.8538 3.9669 1.7969 22.3029
HOP-62 GDSC1; GDSC2; CTRP2 1.8547 5.2217 1.5134 22.4458
NCI-H1648 GDSC1; GDSC2 1.9205 4.3513 1.426 16.8147
LK2 CTRP2 1.9425 2.4938 1.9425 20.6651
NCI-H1944 GDSC1; GDSC2; CTRP2; CTRP1 1.9643 3.6241 1.944 21.4518
RERF-LC-KJ GDSC1; GDSC2; CTRP1 1.9799 3.9218 1.9353 27.4376
NCI-H292 GDSC1; GDSC2; CTRP2 1.9943 4.6819 1.8072 20.9666
NCI-H522 GDSC2; CTRP2; CTRP1 2.0074 3.9943 1.9564 21.271
HCC1195 CTRP2; CTRP1 2.0178 3.9235 1.9751 21.1744
NCI-H196 GDSC1; GDSC2; CTRP2 2.037 3.1139 2.0349 20.043
NCI-H841 GDSC1; GDSC2; CTRP2; CTRP1 2.0387 3.9638 1.993 21.0469
NCI-H2731 GDSC1; GDSC2 2.0411 3.4097 1.8992 13.6058
RERF-LC-Sq1 GDSC1; GDSC2 2.0568 6.238 0.7106 20.4247
HCC2279 CTRP2 2.0612 3.6682 2.0368 19.9565
CAL-12T GDSC1; GDSC2; CTRP2; CTRP1 2.0762 5.1604 1.8033 21.588
SHP-77 GDSC1; GDSC2; CTRP2; CTRP1 2.0862 4.4833 1.9682 20.9805
DMS 114 GDSC1; GDSC2; CTRP2 2.0885 4.0385 2.0272 19.9003
NCI-H2110 GDSC1; GDSC2; CTRP2; CTRP1 2.1349 4.9398 1.9237 20.9845
NCI-H2029 GDSC1; GDSC2; CTRP2; CTRP1 2.1479 4.1201 2.0905 20.3667
HCC366 GDSC1; GDSC2; CTRP2 2.1655 3.9677 2.1178 19.3409
BEN GDSC1; GDSC2; CTRP2; CTRP1 2.1741 3.9081 2.141 20.1122
KNS-62 GDSC1; GDSC2; CTRP2; CTRP1 2.1848 5.4545 1.8385 21.1358
SW1271 GDSC1; GDSC2 2.1949 4.4863 1.6547 14.365
EPLC-272H GDSC1; GDSC2; CTRP2; CTRP1 2.2272 4.8436 2.0469 20.2685
PaCa-3 GDSC1; GDSC2 2.2371 3.6433 2.0369 11.9691
HCC1359 CTRP1 2.2597 4.9628 2.0542 43.0269
NCI-H2286 CTRP2; CTRP1 2.267 4.6236 2.1372 19.8303
NCI-H2141 GDSC1; GDSC2; CTRP2; CTRP1 2.2945 4.8727 2.1135 19.8278
LOU-NH91 GDSC1; GDSC2; CTRP2 2.3073 4.2066 2.2373 18.4727
NCI-H650 GDSC1; GDSC2; CTRP2; CTRP1 2.3309 5.6301 1.9438 20.3232
NCI-H1838 GDSC1; GDSC2; CTRP2 2.3812 5.0783 2.1287 18.6265
NCI-H2444 GDSC1; GDSC2 2.3977 4.7335 1.7504 13.007
Calu-6 GDSC1; GDSC2; CTRP2; CTRP1 2.4175 4.8932 2.2426 18.9966
HCC1438 CTRP2 2.4556 4.7599 2.2915 17.8147
RERF-LC-MS GDSC1; GDSC2; CTRP2 2.4663 4.0255 2.4297 17.2991
NCI-H596 GDSC1; GDSC2; CTRP1 2.4765 4.4026 2.4022 23.3777
COR-L95 GDSC1; CTRP2 2.5012 3.7696 2.4873 16.9898
COR-L105 GDSC1; GDSC2; CTRP2 2.5111 5.8686 2.0177 18.6497
SK-MES-1 GDSC1; GDSC2; CTRP2 2.5168 4.746 2.3613 17.377
NCI-H1623 GDSC1; GDSC2; CTRP2 2.5316 4.325 2.4598 16.9851
NCI-H322M GDSC1; GDSC2 2.5476 7.2039 0.7031 18.7027
LC-1/sq-SF CTRP2; CTRP1 2.5955 3.7304 2.589 17.2467
NCI-H1792 GDSC1; GDSC2; CTRP2; CTRP1 2.6277 5.7684 2.2216 18.4441
NCI-H2087 GDSC1; GDSC2; CTRP2 2.6315 5.2077 2.3647 17.014
NCI-H520 GDSC1; GDSC2; CTRP2 2.639 4.8927 2.4592 16.6503
NCI-H838 GDSC1; GDSC2; CTRP2 2.6436 5.2548 2.364 16.9803
HCC95 CTRP2 2.6747 4.0834 2.6437 15.8917
NCI-H2595 GDSC1; GDSC2 2.6785 4.9154 1.9412 10.8106
NCI-H2030 GDSC1; GDSC2; CTRP2; CTRP1 2.691 4.6301 2.5947 16.9219
HCC4006 CTRP2; CTRP1 2.7087 5.3253 2.4479 17.3853
Lu-99A GDSC1; GDSC2 2.7176 7.0374 0.9393 16.7717
NCI-H1373 CTRP2; CTRP1 2.7232 5.3316 2.4618 17.2918
NCI-H1693 GDSC1; GDSC2; CTRP2 2.7263 4.5953 2.6215 15.8034
NCI-H2066 GDSC1; GDSC2 2.7265 4.5299 2.1708 9.2268
NCI-H1573 GDSC1; GDSC2; CTRP2; CTRP1 2.7442 5.0367 2.5642 16.8637
HCC2935 CTRP2; CTRP1 2.7478 5.114 2.5485 16.9083
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2; CTRP1 2.762 7.1559 1.837 19.5024
T3M-10 CTRP2; CTRP1 2.7647 6.2093 2.2144 18.0783
NCI-H647 GDSC1; GDSC2; CTRP2 2.7798 4.5974 2.679 15.433
ChaGo-K-1 GDSC1; GDSC2; CTRP2; CTRP1 2.7806 5.3667 2.5142 16.9325
NCI-H1339 CTRP2 2.8245 4.4981 2.746 15.0575
NCI-H2461 GDSC1; GDSC2 2.8431 5.5428 1.791 11.1759
NCI-H2810 GDSC1; GDSC2 2.8611 5.3725 1.8911 10.4916
NCI-H2196 GDSC2; CTRP2 2.8744 5.4815 2.5439 15.6337
NCI-H460 GDSC1; GDSC2; CTRP2; CTRP1 2.9179 5.2477 2.698 15.8627
NCI-H322 CTRP2 2.9203 5.0927 2.7129 14.8779
NCI-H1650 GDSC1; GDSC2; CTRP2 2.9232 5.3594 2.6363 15.1491
NCI-H1299 GDSC1; GDSC2; CTRP2; CTRP1 2.9513 5.5669 2.6389 15.9771
NCI-H2405 GDSC1; GDSC2; CTRP2; CTRP1 3.0107 5.9718 2.5657 16.0752
NCI-H1869 GDSC1; GDSC2; CTRP2 3.0331 4.6782 2.9374 13.7284
NCI-H2803 GDSC1; GDSC2 3.0697 5.3681 2.0817 8.6168
LUDLU-1 CTRP2 3.0758 4.6003 2.999 13.3781
NCI-H2085 GDSC1; GDSC2; CTRP2 3.0787 6.8138 2.2489 16.1886
NCI-H1703 GDSC1; GDSC2; CTRP2 3.116 4.8027 3.0006 13.2458
NCI-H2347 GDSC1; GDSC2 3.1522 5.2292 2.2235 7.4642
NCI-H2291 GDSC1; GDSC2; CTRP2 3.1574 5.8493 2.7203 14.1565
NCI-H2591 GDSC1; GDSC2 3.1876 6.1434 1.7978 10.0388
NCI-H513 GDSC1; GDSC2 3.2051 6.0316 1.8686 9.5411
NCI-H441 GDSC1; GDSC2; CTRP2; CTRP1 3.2228 5.5945 2.9252 14.1395
NCI-H2342 GDSC1; GDSC2; CTRP2; CTRP1 3.2541 5.2519 3.0638 13.545
NCI-H1781 GDSC1; GDSC2; CTRP1 3.2586 4.4603 3.2286 16.5878
NCI-H1563 GDSC1; GDSC2; CTRP2 3.2633 7.2206 2.2616 15.653
HCC1171 CTRP2 3.2931 5.9104 2.8425 13.3095
NCI-H1304 GDSC1 3.3834 6.2976 1.885 11.0743
NCI-H2722 GDSC1; GDSC2 3.3863 5.3124 2.3798 5.7801
NCI-H2869 GDSC1; GDSC2 3.4011 5.5708 2.2628 6.4792
NCI-H1355 GDSC1; GDSC2; CTRP2; CTRP1 3.4195 7.4734 2.3785 15.6942
NCI-H727 GDSC1; GDSC2; CTRP2; CTRP1 3.4233 7.5012 2.37 15.7175
NCI-H2023 GDSC1; GDSC2; CTRP2; CTRP1 3.4261 5.8258 3.0659 13.0359
Lu-165 GDSC1; GDSC2 3.4694 5.4216 2.3923 5.4709
SK-LU-1 GDSC1; GDSC2; CTRP2; CTRP1 3.5254 6.0679 3.0822 12.6967
NCI-H1993 GDSC1; GDSC2 3.5566 5.2557 2.543 4.29
NCI-H2172 GDSC1; GDSC2; CTRP2; CTRP1 3.5733 6.2815 3.0489 12.6918
NCI-H3255 GDSC1; GDSC2; CTRP1 3.5779 5.3253 3.396 14.5767
NCI-H2228 GDSC1; GDSC2 3.7068 7.9799 1.3054 11.5965
NCI-H1793 GDSC1; GDSC2; CTRP2; CTRP1 3.7646 6.4518 3.1793 11.6779
Lu-65 GDSC1; GDSC2; CTRP2; CTRP1 3.7788 7.0902 2.9149 12.6754
NCI-H2135 GDSC1; GDSC2 3.8213 11.5113 -0.3644 20.2049
Calu-1 CTRP2 3.8929 8.4511 2.3068 13.9238
NCI-H226 GDSC1; GDSC2 3.9487 8.2591 1.3542 10.6621
EKVX GDSC1; GDSC2; CTRP2 4.0734 7.7631 2.8102 11.4473
RERF-LC-Ad2 CTRP2 4.5381 7.4572 3.3938 7.981
NCI-H1395 CTRP2 4.6321 7.8953 3.2623 8.3259
RERF-LC-Ad1 CTRP2 5.025 7.1498 3.9755 4.5306
Hs 888.Lu CTRP2 3.4842 7.4114 2.3988 14.544
⏷ Show the Full List of 226 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 1.2934 3.151 1.1524 21.0929
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 1.0225 2.7244 1.014 26.8228
P-STS CTRP2 1.1982 2.1737 1.1981 25.6243
H-STS CTRP2 1.4098 2.4131 1.4095 24.2153
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 1.4134 2.9682 1.4051 24.2179
Aska-SS CTRP2 1.7556 2.3317 1.7556 21.9101
Rh30 GDSC1; GDSC2 -1.1489 1.1121 -1.1753 44.9491
Rh41 GDSC1; GDSC2; CTRP2 0.2441 1.9066 0.2415 31.9888
Hs 633.T GDSC1; GDSC2 0.4959 2.4622 0.4229 28.7303
VA-ES-BJ GDSC1; GDSC2 0.7628 4.5918 0.1027 29.0572
EW-8 GDSC1; GDSC2 0.7695 1.8703 0.7634 25.6443
G-401 GDSC1; GDSC2; CTRP2; CTRP1 1.1677 3.4093 1.1295 26.7608
KYM-1 GDSC1; GDSC2; CTRP2 1.1865 3.0218 1.1701 25.7567
Rh18 GDSC1; CTRP2 1.2574 3.4675 1.2118 25.383
MFH-ino GDSC1; GDSC2 1.695 6.1945 0.3767 23.6406
STS-0421 GDSC1; GDSC2 1.7098 3.7166 1.4409 17.6252
RD GDSC1; GDSC2; CTRP2 1.7509 4.2665 1.6287 22.3593
HT-1080 GDSC1; GDSC2; CTRP2; CTRP1 1.8434 4.4644 1.7093 22.6352
SW872 GDSC1; GDSC2 1.9286 3.1472 1.8452 14.4164
TE 617.T CTRP2 2.0097 4.3381 1.8951 20.6095
GCT GDSC1; GDSC2; CTRP2 2.0874 5.3341 1.7338 20.9451
SW982 GDSC1; GDSC2; CTRP2 2.1428 3.8198 2.1094 19.4435
G-402 GDSC1; GDSC2; CTRP2 2.1528 6.1317 1.537 21.4742
A-204 GDSC1; GDSC2; CTRP2 2.1607 5.5758 1.7377 20.7119
TE 441.T GDSC2; CTRP2 2.248 4.4547 2.131 19.0312
Tm87-16 CTRP2 2.3208 6.3481 1.6365 20.6207
TTC-709 CTRP2 2.5098 5.715 2.0699 18.4595
RKN GDSC1; GDSC2; CTRP2; CTRP1 2.6371 4.4837 2.5619 17.2044
MES-SA GDSC1; GDSC2; CTRP2 2.7592 4.5534 2.6653 15.5459
BT-12 CTRP2 2.8254 5.0933 2.6092 15.5411
SK-LMS-1 GDSC1; GDSC2; CTRP2 2.9355 5.4046 2.6354 15.1158
SK-UT-1 GDSC1; GDSC2; CTRP2 3.5422 8.3111 2.0367 15.8467
SW684 GDSC1; GDSC2 3.5535 6.059 2.1413 6.8271
Hs 729.T CTRP2 3.7158 9.0552 1.847 16.1868
BT-16 CTRP2 4.0692 6.5807 3.3647 9.1998
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 2.7703 5.0009 2.5743 15.8346
OVK18 GDSC1; GDSC2; CTRP2; CTRP1 -0.3851 2.7984 -0.4449 37.0526
JHOC-5 CTRP2; CTRP1 0.1248 2.6997 0.0946 33.6051
RMUG-S CTRP1 0.195 2.6448 0.1705 69.3308
OVCAR-5 GDSC1; GDSC2; CTRP2 0.5379 3.5321 0.4416 30.3454
COV434 CTRP2; CTRP1 0.5643 3.1827 0.5169 30.7669
A2780 GDSC1; GDSC2; CTRP2; CTRP1 0.7357 3.5406 0.6612 29.7275
EFO-27 GDSC1; GDSC2; CTRP2; CTRP1 0.8272 3.6004 0.7511 29.1306
OVCAR-8 GDSC1; GDSC2; CTRP2; CTRP1 0.8467 3.047 0.8214 28.8329
ONCO-DG-1 CTRP2 0.9379 3.5511 0.8649 27.604
OV-90 GDSC1; GDSC2; CTRP2; CTRP1 1.0151 4.0561 0.8875 28.066
TYK-nu GDSC1; GDSC2; CTRP2; CTRP1 1.0293 3.7492 0.9475 27.8189
COV644 CTRP2; CTRP1 1.1443 4.289 0.9861 27.3197
OC 314 GDSC1; GDSC2; CTRP2 1.3595 2.5628 1.3582 24.5534
RMG-I GDSC1; GDSC2; CTRP2; CTRP1 1.5048 3.8774 1.4371 24.6388
SNU-8 CTRP2 1.5772 2.9857 1.5715 23.1177
IGROV-1 GDSC1; GDSC2; CTRP2; CTRP1 1.688 3.774 1.6426 23.3564
OAW28 GDSC1; GDSC2; CTRP2 1.7749 4.0853 1.685 22.0877
ES-2 GDSC1; GDSC2 1.7832 2.9115 1.7343 15.6927
TOV-112D GDSC1; GDSC2; CTRP2 1.8931 4.6554 1.7032 21.65
SNU-840 CTRP2; CTRP1 1.9537 5.3595 1.6143 22.6289
HEY A8 CTRP2; CTRP1 2.0806 4.4243 1.9727 20.9828
ES2 CTRP2 2.1032 3.631 2.0833 19.6613
OVCAR-4 GDSC1; GDSC2; CTRP2; CTRP1 2.1217 5.99 1.5983 22.1876
MCAS CTRP2 2.2064 4.1204 2.1418 19.1263
SK-OV-3 GDSC1; GDSC2; CTRP2; CTRP1 2.3924 4.4029 2.3118 18.8351
FU-OV-1 GDSC1; GDSC2; CTRP2 2.4509 5.3857 2.1139 18.4705
Caov-4 GDSC1; GDSC2 2.5334 4.4259 2.0269 10.8227
OVTOKO GDSC1; GDSC2; CTRP2 2.634 4.6949 2.5004 16.5192
DOV13 GDSC1; GDSC2; CTRP2 2.6656 5.3873 2.3472 16.9762
OVKATE GDSC1; GDSC2; CTRP1 2.7091 3.7429 2.7045 21.1149
JHOM-1 CTRP2; CTRP1 2.825 4.2675 2.7911 15.8259
OVCAR-3 GDSC1; GDSC2 2.8583 4.5986 2.2654 8.1715
OVISE GDSC1; GDSC2; CTRP2 2.8614 5.3828 2.5617 15.6068
Kuramochi GDSC1; GDSC2; CTRP2 2.9847 5.7718 2.5631 15.2423
OVMANA CTRP1 3.1894 6.6785 2.4828 33.4957
OAW42 GDSC1; GDSC2; CTRP2; CTRP1 3.1949 5.2346 3.004 13.9364
OV7 CTRP2; CTRP1 3.3331 8.578 1.7868 18.2107
Caov-3 GDSC2; CTRP2; CTRP1 3.563 7.7452 2.4002 15.2471
TOV-21G GDSC1; GDSC2; CTRP2 3.6163 6.8107 2.8036 12.594
JHOS-2 GDSC1; GDSC2; CTRP2 3.7356 7.2165 2.7393 12.5498
OVSAHO CTRP2 3.7624 6.5657 3.0615 11.1919
COV318 CTRP1 3.9071 7.6936 2.7657 27.1964
JHOS-4 GDSC1; GDSC2; CTRP1 3.957 11.1906 1.1203 23.9472
EFO-21 GDSC1; GDSC2; CTRP2; CTRP1 4.1463 6.6161 3.5002 9.4363
SNU-119 CTRP2 4.1899 8.9173 2.3567 13.0429
COV362 CTRP2; CTRP1 4.9004 7.4719 3.8114 6.4307
OV56 GDSC1; GDSC2; CTRP2 4.971 6.3456 4.3317 3.1405
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 3.7345 5.3954 3.5056 9.5467
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; GDSC2; CTRP2; CTRP1 1.4423 5.1756 1.1074 25.9684
NCI-H28 GDSC1; GDSC2; CTRP2; CTRP1 1.8439 4.0515 1.7757 22.4065
MPP 89 GDSC1; GDSC2; CTRP2 2.5593 5.4376 2.2156 17.7753
NCI-H2052 GDSC1; GDSC2; CTRP2; CTRP1 2.6535 5.6493 2.2887 18.1242
NCI-H2452 GDSC1; GDSC2 2.8199 5.0176 2.0264 9.7879
IST-Mes1 GDSC1; GDSC2; CTRP2 3.1226 5.8475 2.6837 14.3938
JL-1 CTRP2 3.3551 5.0971 3.1861 11.8472
ACC-MESO-1 CTRP2 3.8708 5.5265 3.6058 8.7786
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H660 GDSC2; CTRP2 0.412 3.0461 0.3627 31.0261
22Rv1 GDSC1; GDSC2; CTRP2 1.0869 3.411 1.0378 26.5307
VCaP GDSC1; GDSC2; CTRP2 1.5191 3.3723 1.4937 23.5711
LNCaP clone FGC GDSC1; GDSC2; CTRP2 2.0113 4.4856 1.8684 20.6981
PC-3 GDSC1; GDSC2 2.5578 6.4592 1.0784 16.4948
DU145 GDSC1; GDSC2; CTRP2 2.6242 4.8842 2.4451 16.746
PaCa-3 CTRP2; CTRP1 4.3668 6.2435 3.8909 7.3365
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 2.2869 4.27 2.2056 18.6479
A-253 GDSC1; GDSC2; CTRP2 2.3869 4.786 2.2104 18.316
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -0.871 2.2792 -1.0172 42.5743
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 GDSC1; GDSC2; CTRP2 -0.3814 1.3184 -0.3828 36.1521
AGS GDSC1; GDSC2; CTRP2; CTRP1 -0.3057 1.3251 -0.3065 36.3457
NUGC-4 GDSC1; GDSC2; CTRP2; CTRP1 -0.2711 1.7781 -0.2763 36.1319
TMK-1 GDSC1; GDSC2 -0.0484 2.3262 -0.14 34.2668
GSS CTRP2 0.0591 1.641 0.0577 33.2173
HSC-39 GDSC1; GDSC2 0.324 2.1728 0.2776 30.3185
Fu97 GDSC1; GDSC2; CTRP1 0.3314 3.1784 0.2727 41.3565
NCC-StC-K140 CTRP2 0.4657 13.4576 -8.5058 24.2266
SK-GT-2 GDSC1; GDSC2 0.542 2.9938 0.371 28.7703
OCUM-1 GDSC1; GDSC2 0.5999 2.3132 0.5538 27.5498
SNU-16 GDSC1; GDSC2; CTRP2 0.8166 2.504 0.8104 28.187
HGC-27 GDSC1; GDSC2; CTRP2 0.8216 5.9607 0.1567 30.3506
SNU-620 CTRP2 0.878 2.053 0.8776 27.7586
SNU-216 CTRP2 1.0658 3.7347 0.9773 26.8051
RF-48 GDSC1; GDSC2 1.1068 3.1688 0.9446 23.0758
RERF-GC-1B GDSC1; GDSC2 1.2255 4.3425 0.6923 23.9077
23132/87 GDSC1; GDSC2; CTRP2 1.2648 2.9492 1.2538 25.2167
SCH GDSC1; GDSC2 1.3143 2.7484 1.2567 20.4419
TGBC11TKB GDSC1; GDSC2 1.3948 2.8455 1.3271 19.6874
MKN28 GDSC1; GDSC2 1.6134 4.5217 1.0332 20.347
KE-39 CTRP2 1.6412 4.5312 1.4569 23.3065
NCI-N87 GDSC1; GDSC2; CTRP2 1.6557 3.0746 1.649 22.5984
SNU-719 CTRP2 1.7494 7.2749 0.6644 25.795
Hs 746.T GDSC1; GDSC2; CTRP2 1.7563 3.6711 1.7172 22.0374
SNU-1 GDSC1; GDSC2; CTRP2 1.7991 4.3015 1.6743 22.0474
GSU CTRP2 1.8551 2.9283 1.8536 21.2525
GCIY GDSC1; GDSC2 1.8778 3.5336 1.6834 15.5299
SNU-601 CTRP2 1.9985 4.0771 1.9257 20.5392
NUGC-3 GDSC1; GDSC2; CTRP2 2.0218 4.5947 1.8568 20.7058
SNU-668 CTRP2 2.0892 4.563 1.9368 20.2128
IM95 GDSC1; GDSC2; CTRP2 2.0932 4.4206 1.97 20.0836
KATO III GDSC1; GDSC2; CTRP2 2.1283 4.024 2.0715 19.6199
SNU-5 GDSC1; GDSC2; CTRP2 2.1425 3.961 2.0943 19.4958
ECC12 GDSC2; CTRP2 2.4172 4.0896 2.3704 17.6609
MKN74 CTRP2; CTRP1 2.4355 4.56 2.3316 18.6311
SH-10-TC CTRP2; CTRP1 2.9136 4.3516 2.8755 15.2561
MKN7 GDSC1; GDSC2; CTRP2; CTRP1 2.9469 5.3305 2.7062 15.7463
MKN1 GDSC1; GDSC2 3.0635 5.7371 1.8928 9.8249
HuG1-N CTRP2 3.5391 6.4184 2.8956 12.4322
LMSU CTRP2 5.2595 7.9185 3.7824 4.9037
MKN45 GDSC1; GDSC2; CTRP2 6.0638 9.8388 3.4345 5.0335
SNU-1077 CTRP2 1.8254 3.9034 1.7645 21.6516
SNU-685 CTRP2 2.3587 5.2785 2.0463 18.9932
SNG-M GDSC1; GDSC2; CTRP2; CTRP1 2.4074 4.3718 2.3327 18.7158
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1; GDSC2 0.7433 1.8696 0.7367 25.9102
ML-1 [Human leukemia] GDSC1; GDSC2 1.177 5.081 0.344 25.9722
8505C GDSC1; GDSC2; CTRP2 1.3195 3.3588 1.2865 24.9265
BHT-101 GDSC1; GDSC2; CTRP2 1.3203 3.7904 1.2413 25.0778
B-CPAP GDSC1; GDSC2; CTRP2 1.3447 3.0823 1.3302 24.6964
K5 GDSC1; GDSC2 1.3696 3.5819 1.115 20.946
TT GDSC1; GDSC2; CTRP2 1.5654 5.2115 1.2007 24.4483
CAL-62 GDSC1; GDSC2; CTRP2 1.6888 3.6095 1.6519 22.4798
CGTH-W-1 GDSC1; GDSC2; CTRP2 1.7355 3.6001 1.7018 22.1575
KMH-2 GDSC1; GDSC2 1.7587 2.7925 1.7259 15.8546
8305C GDSC1; GDSC2; CTRP2 1.801 3.4875 1.7789 21.6822
HTC-C3 GDSC1; GDSC2 2.0107 4.5124 1.4528 16.2915
SW579 CTRP2 2.0306 4.4041 1.9055 20.5069
ASH-3 GDSC1; GDSC2 2.2275 3.8474 1.9519 12.4944
TT2609-C02 GDSC1; GDSC2; CTRP2 2.4898 5.338 2.1711 18.145
FTC-238 CTRP2 2.5175 4.3466 2.4411 17.095
FTC-133 GDSC1; GDSC2; CTRP2 2.5752 4.6842 2.4388 16.9205
WRO GDSC1; GDSC2 3.3528 6.6491 1.684 10.2617
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-06A GDSC1; GDSC2 -0.7176 1.2392 -0.7365 40.621
BICR 78 GDSC1; GDSC2 -0.6066 1.514 -0.639 39.5686
NCI-H3118 GDSC1; GDSC2 -0.549 2.0538 -0.636 39.2206
SKN-3 GDSC1; GDSC2 -0.3047 2.3706 -0.4227 36.933
PCI-04B GDSC1; GDSC2 -0.2905 1.707 -0.3241 36.413
JHU-011 GDSC1; GDSC2 -0.1883 3.3579 -0.5188 36.6743
Ca9-22 GDSC1; GDSC2 0.3314 1.853 0.3132 30.1021
SAS GDSC1; GDSC2 0.3358 2.9385 0.1592 30.852
SAT [Human HNSCC] GDSC1; GDSC2 0.6641 4.4091 0.0657 29.7027
HO-1-N-1 GDSC1; GDSC2 0.7361 3.2961 0.507 27.1341
JHU-022 GDSC1; GDSC2 0.7425 4.9695 -0.0672 29.9609
JHU-029 GDSC1; GDSC2 0.7693 3.084 0.5973 26.5049
HO-1-u-1 GDSC1; GDSC2 0.7983 2.696 0.71 25.778
PE/CA-PJ49 CTRP2 0.9012 2.6333 0.893 27.6297
BICR 56 CTRP2 0.9685 3.4852 0.905 27.368
SCC-4 GDSC1; GDSC2; CTRP2 1.0026 4.184 0.8351 27.4961
PCI-38 GDSC1 1.14 5.4403 0.1529 32.9926
KON GDSC1; GDSC2 1.4061 3.7965 1.0847 20.95
BICR 10 GDSC1; GDSC2 1.45 4.2487 0.968 21.4085
KOSC-2 GDSC1; GDSC2 1.5228 3.5268 1.2989 19.2456
PCI-30 GDSC1; GDSC2 1.5429 7.5023 -0.388 27.931
SNU-899 CTRP2 1.648 4.4907 1.473 23.229
DOK GDSC1; GDSC2 1.6686 3.8811 1.339 18.3769
Detroit 562 GDSC1; GDSC2; CTRP2 1.7404 4.0727 1.6499 22.3192
OSC-19 GDSC1; GDSC2 1.755 5.554 0.731 21.4778
BB30-HNC GDSC1; GDSC2 1.7951 3.677 1.5467 16.6578
SNU-1076 CTRP2 2.0006 3.9823 1.9409 20.4801
HSC-3 GDSC1; GDSC2; CTRP2 2.0673 4.3547 1.9543 20.2204
SNU-1214 CTRP2 2.0825 4.4832 1.9461 20.2011
SCC-25 GDSC1; GDSC2; CTRP2 2.0966 4.4923 1.9596 20.1093
HSC-2 GDSC1; GDSC2; CTRP2; CTRP1 2.1264 4.8092 1.9451 20.9353
SNU-46 CTRP2 2.221 4.8502 2.0139 19.5294
YD-8 CTRP2 2.3582 4.1538 2.2993 18.0952
SCC-15 GDSC1; GDSC2 2.448 6.3841 1.013 17.2632
CAL-27 GDSC1; GDSC2; CTRP2 2.4667 4.1376 2.417 17.3412
BICR 6 CTRP2 2.5323 5.175 2.2662 17.671
HSC-4 GDSC1; GDSC2; CTRP2 2.5601 5.1853 2.2935 17.4879
SNU-1041 CTRP2 2.5856 5.6937 2.1594 17.9057
BICR 18 CTRP2 2.5889 5.0367 2.3667 17.1356
CAL-33 GDSC1; GDSC2; CTRP2 2.6226 4.5553 2.5171 16.4961
BHY GDSC1; GDSC2; CTRP2 2.6235 5.8155 2.1579 17.8014
SCC-9 GDSC1; GDSC2; CTRP2; CTRP1 2.629 4.6245 2.5287 17.344
BICR 22 GDSC1; GDSC2; CTRP2 2.6346 5.1164 2.3945 16.8967
FaDu GDSC1; GDSC2; CTRP2 2.7315 5.0787 2.5109 16.1816
BB49-HNC GDSC1; GDSC2 2.8127 5.2901 1.8868 10.6816
OSC-20 GDSC1; GDSC2 2.9643 8.9542 0.2024 20.0212
UPCI-SCC-090 GDSC1; GDSC2 3.0916 6.2369 1.6683 11.1436
BICR 31 GDSC2; CTRP2 3.1552 5.7174 2.7663 13.9889
PE/CA-PJ34 (clone C12) CTRP2 3.3 5.1508 3.1106 12.288
LB771-HNC GDSC1; GDSC2 3.3165 4.9096 2.5235 5.0709
PE/CA-PJ41 (clone D2) CTRP2 3.4801 4.9996 3.3492 10.8781
PCI-15A GDSC1; GDSC2 3.6683 5.1489 2.6786 3.17
BICR 16 CTRP2 3.8619 7.71 2.6321 12.675
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 4.0704 8.0732 2.6576 12.0802
SNU-1066 CTRP2 4.3005 6.7666 3.5054 8.064
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
253J CTRP2 0.9409 3.7999 0.8343 27.6986
5637 GDSC1; GDSC2; CTRP2; CTRP1 1.0916 2.9108 1.0802 27.1729
U-BLC1 CTRP2 1.1666 2.8998 1.1551 25.8731
KU-19-19 GDSC1; GDSC2; CTRP2 1.3335 2.4526 1.3328 24.7246
TCCSUP GDSC1; GDSC2; CTRP2 1.4104 4.2566 1.2625 24.7157
JMSU-1 CTRP2 1.4559 3.6091 1.4068 24.0729
RT-112 GDSC1; GDSC2; CTRP2 1.4992 4.5978 1.2875 24.3474
CAL-29 GDSC1; GDSC2; CTRP2 1.5183 3.2846 1.4986 23.5574
BFTC-905 GDSC1; GDSC2 1.6868 3.648 1.4388 17.7382
UM-UC-1 CTRP2 1.8632 6.5401 1.0742 24.0097
SCaBER CTRP2 2.0304 4.1188 1.9538 20.3401
KMBC-2 CTRP2; CTRP1 2.0526 4.9555 1.8302 21.5651
647V GDSC1; GDSC2; CTRP2 2.2312 4.6857 2.0642 19.3189
RT-4 GDSC1; GDSC2; CTRP2; CTRP1 2.3661 4.4925 2.2686 19.0662
VM-CUB-1 CTRP2 2.3729 4.1481 2.3158 17.9913
253J-BV CTRP2 2.4281 4.4416 2.3282 17.7719
HT-1376 GDSC1; GDSC2; CTRP2; CTRP1 2.4444 4.1553 2.401 18.3659
SW780 GDSC1; GDSC2 2.6249 4.5402 2.0658 10.242
SW1710 GDSC1; GDSC2; CTRP2 2.7989 4.9439 2.6206 15.5808
HT-1197 GDSC1; GDSC2; CTRP2 3.0744 4.0627 3.0632 13.1619
T24 GDSC1; GDSC2; CTRP2 3.1411 6.5207 2.4373 15.2883
BC-3C CTRP2 3.387 5.29 3.163 11.8359
UM-UC-3 GDSC1; GDSC2; CTRP2; CTRP1 3.5916 6.9957 2.766 13.7381
639V GDSC1; GDSC2; CTRP2 4.0794 6.2394 3.5296 8.5132
J82 GDSC1; GDSC2; CTRP2 4.3817 9.1725 2.405 12.4233
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NEC8 GDSC1; GDSC2 -1.3399 -0.0098 -1.3404 46.7835
PA-1 GDSC1; GDSC2 -0.8528 1.2746 -0.8784 41.9987
SW954 GDSC1; GDSC2 0.1163 2.2827 0.0427 32.5348
TC-YIK GDSC1; GDSC2 0.131 2.2406 0.0642 32.3544
NT2-D1 GDSC1; GDSC2 0.4629 2.7355 0.3401 29.3147
OV17R GDSC1; GDSC2 0.4682 4.1612 -0.0562 31.2298
PWR-1E GDSC1; GDSC2 0.5119 1.8768 0.4986 28.2659
HEY GDSC1; GDSC2 0.5817 2.3402 0.5312 27.7548
C-33 A GDSC1; GDSC2 0.902 2.6421 0.8307 24.6495
SiSo GDSC1; GDSC2 1.008 3.5966 0.7167 24.7544
MS751 GDSC1; GDSC2 1.0319 3.7583 0.6914 24.7804
C-4-I GDSC1; GDSC2 1.1149 2.997 0.9936 22.7769
CAL-39 GDSC1; GDSC2 1.133 3.2624 0.9491 22.9289
SKN GDSC1; GDSC2 1.2272 3.2925 1.0438 21.9836
NCC-IT GDSC2 1.2871 4.1015 0.8484 22.782
DSH1 GDSC1; GDSC2 1.3144 3.2442 1.1518 20.9982
Ca Ski GDSC1; GDSC2 1.3371 3.7779 1.0162 21.6355
SKG-IIIa GDSC1; GDSC2 1.3498 3.1047 1.2249 20.441
JAR GDSC1; GDSC2 1.4377 2.6952 1.3967 19.118
DoTc2 4510 GDSC1; GDSC2 1.4986 5.6089 0.4468 24.0664
HEC-1 GDSC1; GDSC2 1.508 2.9513 1.4298 18.6073
JEG-3 GDSC1; GDSC2 1.62 2.5277 1.6068 17.1459
BPH-1 GDSC1; GDSC2 1.6624 4.0697 1.2631 18.8327
ACC-OV7 GDSC1; GDSC2 1.728 4.385 1.2096 18.8608
OVMIU GDSC1; GDSC2 1.7479 4.6065 1.1393 19.1827
OVCA433 GDSC1; GDSC2 1.8489 3.2773 1.7264 15.4255
OVCA420 GDSC1; GDSC2 1.9826 3.629 1.7662 14.6045
ME-180 GDSC1; GDSC2 1.9845 3.575 1.7862 14.4842
HeLa GDSC1; GDSC2; CTRP2 2.1767 4.3748 2.0689 19.4738
HT-3 GDSC1; GDSC2 2.1781 4.1739 1.7697 13.7555
UWB1.289 GDSC1; GDSC2 2.2565 4.9284 1.5198 14.9316
SW756 GDSC1; GDSC2 2.4734 5.8964 1.2737 15.6213
KGN GDSC1; GDSC2 2.5367 5.5862 1.4834 14.1256
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 2.6159 4.374 2.1334 9.8656
PEO1 GDSC1; GDSC2 2.6911 4.2372 2.2713 8.7462
SW962 GDSC1; GDSC2 2.7708 4.7847 2.0924 9.5499
LB831-BLC GDSC1; GDSC2 2.9061 5.8722 1.6856 11.6252
SiHa GDSC1; GDSC2 3.3446 4.7184 2.6425 4.2361
JHOS-3 GDSC1; GDSC2 3.7544 5.5636 2.5379 3.8393
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

Drug Inactive Ingredient(s) (DIG) and Formulation(s) of This Drug

DIG
DIG Name DIG ID PubChem CID Functional Classification
Sodium lauryl sulfate E00464 3423265 Emulsifying agent; Modified-release agent; Penetration agent; Solubilizing agent; Surfactant; lubricant
Carmellose sodium E00625 Not Available Disintegrant
Magnesium stearate E00208 11177 lubricant
Titanium dioxide E00322 26042 Coating agent; Colorant; Opacifying agent
Pharmaceutical Formulation
Formulation Name Drug Dosage Dosage Form Route
Vorinostat 100 mg capsule 100 mg Oral Capsule Oral
Jump to Detail Pharmaceutical Formulation Page of This Drug

References

1 Vorinostat FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6852).
3 BDDCS predictions, self-correcting aspects of BDDCS assignments, BDDCS assignment corrections, and classification for more than 175 additional drugs
4 Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds
5 ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.
6 Protein methyltransferases as a target class for drug discovery. Nat Rev Drug Discov. 2009 Sep;8(9):724-32.
7 A pharmacogenetic study of vorinostat glucuronidation. Pharmacogenet Genomics. 2010 Oct;20(10):638-41.
8 Age-dependent hepatic UDP-glucuronosyltransferase gene expression and activity in children. Front Pharmacol. 2016 Nov 16;7:437.
9 Uridine 5'-diphospho-glucuronosyltransferase genetic polymorphisms and response to cancer chemotherapy. Future Oncol. 2010 Apr;6(4):563-85.
10 Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests. Arch Toxicol. 2017 Feb;91(2):839-864.
11 Proteomic analysis revealed association of aberrant ROS signaling with suberoylanilide hydroxamic acid-induced autophagy in Jurkat T-leukemia cells. Autophagy. 2010 Aug;6(6):711-24. doi: 10.4161/auto.6.6.12397. Epub 2010 Aug 17.
12 A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 2015 Sep;89(9):1599-618.