Details of the Drug

General Information of Drug (ID: DMWPA4L)

Drug Name
PF-07055480
Synonyms giroctocogene fitelparvovec
Indication
Disease Entry ICD 11 Status REF
Haemophilia A 3B10.0 Phase 3 [1]
Drug Type
Gene therapy
Cross-matching ID
UNII
C43ZSD4HNV
DrugBank ID
DB16174
TTD ID
DZ9AJ3

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor VIII (F8) TT1290U FA8_HUMAN Replacement [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Haemophilia A
ICD Disease Classification 3B10.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Coagulation factor VIII (F8) DTT F8 1.08E-22 0.89 1.82
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04370054) Study to Evaluate the Efficacy and Safety of PF-07055480 in Moderately Severe to Severe Hemophilia A Adults (AFFINE). U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Pfizer.