Details of the Drug

General Information of Drug (ID: DMWVBS2)

Drug Name
NXN-462
Synonyms NNOS inhibitor (chronic headache), Neuraxon; NNOS inhibitor (neuropathic pain), NeurAxon
Indication
Disease Entry ICD 11 Status REF
Headache 8A80-8A84 Phase 2 [1]
Cross-matching ID
PubChem CID
11955738
TTD ID
D0W9IT
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Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Nitric-oxide synthase brain (NOS1) TTZUFI5 NOS1_HUMAN Inhibitor [1]
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Molecular Expression Atlas of This Drug

The Studied Disease Headache
ICD Disease Classification 8A80-8A84
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Nitric-oxide synthase brain (NOS1) DTT NOS1 5.20E-01 0.02 0.07
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References

1 ClinicalTrials.gov (NCT01748877) Efficacy, Tolerability, and Safety of NXN-462 in Patients With Post-Herpetic Neuralgia. U.S. National Institutes of Health.