Details of the Drug

General Information of Drug (ID: DMWYF1H)

Drug Name
AZD8186
Synonyms
AZD8186; 1627494-13-6; AZD-8186; AIQ4OWD0RA; UNII-AIQ4OWD0RA; CHEMBL3408248; AZD 8186; 8-[(1R)-1-(3,5-difluoroanilino)ethyl]-N,N-dimethyl-2-morpholin-4-yl-4-oxochromene-6-carboxamide; SCHEMBL1636956; GTPL8527; MolPort-039-137-739; EX-A1649; BDBM50070322; s7694; AKOS025404922; ZINC116734639; CS-4975; ACN-037528; SB16709; KS-0000063L; AK174916; AC-29024; HY-12330; KB-334360; B5950; AZD8186; 1627494-13-6; AZD-8186; AIQ4OWD0RA; UNII-AIQ4OWD0RA;
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 457.5
Logarithm of the Partition Coefficient (xlogp) 3
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C24H25F2N3O4
IUPAC Name
8-[(1R)-1-(3,5-difluoroanilino)ethyl]-N,N-dimethyl-2-morpholin-4-yl-4-oxochromene-6-carboxamide
Canonical SMILES
C[C@H](C1=CC(=CC2=C1OC(=CC2=O)N3CCOCC3)C(=O)N(C)C)NC4=CC(=CC(=C4)F)F
InChI
InChI=1S/C24H25F2N3O4/c1-14(27-18-11-16(25)10-17(26)12-18)19-8-15(24(31)28(2)3)9-20-21(30)13-22(33-23(19)20)29-4-6-32-7-5-29/h8-14,27H,4-7H2,1-3H3/t14-/m1/s1
InChIKey
LMJFJIDLEAWOQJ-CQSZACIVSA-N
Cross-matching ID
PubChem CID
52913813
CAS Number
1627494-13-6
UNII
AIQ4OWD0RA
DrugBank ID
DB15029
TTD ID
D03BHZ
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PI3-kinase beta (PIK3CB) TTTHBCA PK3CB_HUMAN Inhibitor [2]
PI3-kinase gamma (PIK3CG) TTHBTOP PK3CG_HUMAN Inhibitor [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) OTUYHB84 MLP3B_HUMAN Gene/Protein Processing [4]
Proline-rich AKT1 substrate 1 (AKT1S1) OT4JHN4Y AKTS1_HUMAN Post-Translational Modifications [4]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Post-Translational Modifications [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PI3-kinase gamma (PIK3CG) DTT PIK3CG 1.98E-01 -0.05 -0.55
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 4.3399 8.4544 1.5466 8.5214
EW-12 GDSC2 1.8571 10.4441 -1.5231 30.9984
HuO9 GDSC1; GDSC2 2.0708 6.4496 0.6232 20.7902
EW-7 GDSC1; GDSC2 2.7969 8.4423 0.3121 19.9328
G-292 clone A141B1 GDSC1; GDSC2 2.8322 9.7863 -0.3269 22.9503
EW-1 GDSC1; GDSC2 3.2894 9.1892 0.3612 18.1267
ES1 GDSC1; GDSC2 3.3725 8.6952 0.6773 16.1606
CHSA0011 GDSC1; GDSC2 3.4261 14.2018 -2.0315 27.594
ES8 GDSC1; GDSC2 3.4309 6.7193 1.7132 9.8209
SK-ES-1 GDSC1; GDSC2 3.4362 7.2069 1.4738 11.2861
ES5 GDSC1; GDSC2 3.5356 10.2652 0.0268 19.1074
EW-3 GDSC1; GDSC2 3.5379 7.6308 1.3447 11.7859
ES7 GDSC1; GDSC2 3.7414 14.8474 -2.0951 26.9263
EW-11 GDSC1; GDSC2 3.9194 11.0387 -0.0505 18.4011
EW-18 GDSC1; GDSC2 4.0647 8.0201 1.5594 9.0985
ES6 GDSC1; GDSC2 4.2602 8.948 1.2474 10.4821
NOS-1 [Human HNSCC] GDSC1; GDSC2 4.3106 13.6763 -1.0561 21.7687
HOS GDSC1; GDSC2 4.363 9.1226 1.2368 10.2968
H-EMC-SS GDSC1; GDSC2 4.3756 9.3009 1.1586 10.7217
SJSA-1 GDSC1; GDSC2 4.3838 9.5911 1.0223 11.486
CADO-ES1 GDSC1; GDSC2 4.3838 6.4954 2.5085 2.7496
CAL-72 GDSC1; GDSC2 4.4843 8.6974 1.5304 8.2901
EW-22 GDSC1; GDSC2 4.517 9.654 1.0881 10.792
MG-63 GDSC1; GDSC2 4.5502 10.5748 0.6612 13.0933
TC-71 GDSC1; GDSC2 4.7191 12.2285 -0.0274 16.2166
ES4 GDSC1; GDSC2 4.7971 11.0812 0.5924 12.8761
EW-16 GDSC2 4.8212 9.3119 1.4655 7.9684
EW-13 GDSC1; GDSC2 4.8571 10.5793 0.8794 11.1823
CHSA0108 GDSC1; GDSC2 4.8814 12.7545 -0.1663 16.4859
CHSA8926 GDSC1; GDSC2 4.9128 19.2712 -3.3688 27.5813
EW-24 GDSC1; GDSC2 5.0652 9.9718 1.3135 8.3059
CAL-78 GDSC1; GDSC2 5.1817 7.768 2.3906 2.2042
SaOS-2 GDSC1; GDSC2 5.2281 13.0778 -0.0731 15.2356
A-673 GDSC1; GDSC2 5.3204 11.3826 0.8109 10.5487
U2OS GDSC1; GDSC2 5.3498 12.236 0.4208 12.5287
HuO-3N1 GDSC1; GDSC2 5.7588 15.4378 -0.8448 17.4712
MHH-ES-1 GDSC1; GDSC2 6.0673 12.6263 0.7102 9.6008
U-CH2 GDSC2 6.466 20.7874 -2.9493 23.2312
SK-PN-DW GDSC1; GDSC2 6.8321 20.3935 -2.4949 21.1387
NY GDSC1; GDSC2 7.7458 23.5596 -3.3893 22.0142
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 168 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 4.8283 12.8093 -0.2324 16.9231
SU-DHL-5 GDSC1; GDSC2 -3.6672 0.1393 -3.7275 67.3886
SU-DHL-6 GDSC1; GDSC2 -3.0408 -1.0375 -3.0425 63.4688
WSU-NHL GDSC1; GDSC2 -2.6408 -0.0063 -2.6572 59.3031
RPMI-8866 GDSC1 -2.1778 10.0088 -6.1973 47.8394
SU-DHL-1 GDSC2 -1.9909 10.7103 -5.3815 51.3459
EHEB GDSC1 -1.3118 7.6742 -4.2483 42.3125
HT GDSC1; GDSC2 -1.2737 13.6403 -6.0334 48.575
MC116 GDSC1; GDSC2 -1.1436 6.0305 -2.4879 46.5602
SUP-B8 GDSC1; GDSC2 -0.9763 7.3577 -2.8619 45.953
RCH-ACV GDSC1; GDSC2 -0.7586 5.8743 -2.0178 43.7782
NCI-H929 GDSC1; GDSC2 0.0395 3.4728 -0.3026 34.4173
JVM-2 GDSC1; GDSC2 0.051 10.3633 -3.1933 41.6443
Karpas-422 GDSC1; GDSC2 0.1915 16.0941 -5.8296 43.8178
GDM-1 GDSC1; GDSC2 0.3702 4.4892 -0.2795 32.614
DoHH2 GDSC2 0.4744 1.69 0.468 28.6076
SU-DHL-16 GDSC1; GDSC2 0.5115 2.7713 0.3857 28.7426
HAL-01 GDSC1; GDSC2 0.6171 5.8219 -0.5525 32.5462
Kasumi-1 GDSC1; GDSC2 0.7313 8.2171 -1.5176 35.3066
GA-10 GDSC1; GDSC2 0.8351 6.3902 -0.5767 31.6377
CESS GDSC1; GDSC2 0.8396 7.9178 -1.271 34.0941
Farage GDSC1; GDSC2 0.8689 4.3673 0.3011 27.4826
HH [Human lymphoma] GDSC1; GDSC2 0.9645 14.7153 -4.4416 40.0973
BONNA-12 GDSC2 1.0003 7.5466 -0.9394 32.3726
RPMI-8402 GDSC1; GDSC2 1.1275 12.6282 -3.2663 37.7684
NALM-6 GDSC1; GDSC2 1.1384 9.1488 -1.5644 33.7587
CTB-1 GDSC1; GDSC2 1.2003 17.2951 -5.503 40.648
Mono-Mac-6 GDSC1; GDSC2 1.3056 8.177 -0.9386 31.0112
ARH-77 GDSC1; GDSC2 1.3844 8.1161 -0.8336 30.3011
MM1.S GDSC2 1.4823 5.0875 0.6588 22.9897
NU-DUL-1 GDSC1; GDSC2 1.5175 6.0874 0.2493 24.9369
SU-DHL-10 GDSC1; GDSC2 1.5813 3.4996 1.3709 18.5209
NB4 GDSC1; GDSC2 1.5879 6.707 0.0318 25.7351
WSU-DLCL2 GDSC1; GDSC2 1.6708 6.0474 0.4208 23.4272
RL GDSC1; GDSC2 1.7231 22.8608 -7.8099 41.4383
Jurkat GDSC1; GDSC2 1.7906 6.3265 0.4093 23.0157
JeKo-1 GDSC1; GDSC2 1.8139 15.5119 -4.0713 36.9923
SKM-1 GDSC1; GDSC2 1.8493 8.6282 -0.64 27.7321
OCI-Ly7 GDSC1; GDSC2 1.9333 8.006 -0.2585 25.7644
P30/OHK GDSC1; GDSC2 1.9775 9.0711 -0.7378 27.6561
OCI-AML-5 GDSC1 2.0219 8.6032 -1.7531 19.8361
P32/ISH GDSC1; GDSC2 2.0261 8.1146 -0.2247 25.2645
SU-DHL-4 GDSC1; GDSC2 2.1369 5.4861 1.1433 17.5671
CMK GDSC1 2.273 4.6411 0.3722 4.6615
MLMA GDSC1; GDSC2 2.2938 12.2564 -2.0286 30.9888
THP-1 GDSC1; GDSC2 2.3221 9.6054 -0.6876 26.2266
MOLP-8 GDSC1; GDSC2 2.3586 6.9354 0.6608 19.5362
KMS-11 GDSC1; GDSC2 2.373 6.7504 0.7645 18.9023
NK-92MI GDSC2 2.3794 9.6421 -0.6543 25.9604
MOLM-13 GDSC1; GDSC2 2.6068 8.2349 0.2467 20.9053
Karpas-1106P GDSC1; GDSC2 2.6713 8.6722 0.087 21.5007
ATN-1 GDSC1; GDSC2 2.7077 6.6785 1.1078 15.7574
MHH-PREB-1 GDSC1; GDSC2 2.7181 9.8607 -0.4634 23.9343
PL-21 GDSC1; GDSC2 2.7317 10.4641 -0.7522 25.1202
RPMI-6666 GDSC1; GDSC2 2.931 12.9927 -1.8429 28.4392
SUP-HD1 GDSC1; GDSC2 2.9607 7.6569 0.8465 16.4631
Karpas-45 GDSC1; GDSC2 3.0202 7.3309 1.0608 15.0258
Jiyoye GDSC1; GDSC2 3.0337 15.8406 -3.1792 31.7718
KY821 GDSC1; GDSC2 3.0341 7.6045 0.9362 15.713
TALL-1 [Human adult T-ALL] GDSC2 3.0549 5.4876 2.0092 9.1199
HL-60 GDSC1; GDSC2 3.0729 8.4676 0.5388 17.8363
697 GDSC1; GDSC2 3.0915 12.3169 -1.3689 26.3603
MOLM-16 GDSC1; GDSC2 3.1292 11.0201 -0.6889 23.6022
KMS-12-BM GDSC2 3.231 6.5453 1.6338 10.9335
SR GDSC1; GDSC2 3.233 8.1567 0.83 15.7145
GR-ST GDSC1; GDSC2 3.2814 8.1313 0.8834 15.262
A4/Fukuda GDSC1; GDSC2 3.2953 9.949 -0.0139 20.0201
ML-2 GDSC1; GDSC2 3.3427 8.0498 0.9753 14.5474
MHH-CALL-4 GDSC2 3.3927 11.3301 -0.6233 22.5883
JURL-MK1 GDSC1 3.3941 5.62 0.5562 1.5395
MHH-CALL-2 GDSC1; GDSC2 3.4138 5.4135 2.3517 5.8605
Namalwa GDSC1; GDSC2 3.4356 8.7853 0.6843 15.9356
L-1236 GDSC1; GDSC2 3.4517 8.6139 0.7833 15.3317
PF-382 GDSC1; GDSC2 3.6417 6.383 2.0491 7.1475
KE-37 GDSC1; GDSC2 3.708 6.4943 2.0449 7.0022
SCC-3 GDSC2 3.7236 5.7918 2.4037 4.745
CA46 GDSC1; GDSC2 3.7356 10.7293 -0.0429 18.8763
RS4;11 GDSC1; GDSC2 3.7685 9.8516 0.4214 16.4181
EM-2 GDSC1; GDSC2 3.8116 6.4243 2.1575 6.0425
OCI-M1 GDSC1; GDSC2 3.8208 5.405 2.6611 2.9265
BALL-1 GDSC1; GDSC2 3.838 6.5818 2.0996 6.3373
Daudi GDSC1; GDSC2 3.8659 10.0365 0.4065 16.2281
SUP-B15 GDSC2 3.9053 6.1209 2.3738 4.504
EJM GDSC1; GDSC2 3.9641 8.1369 1.4264 10.1534
MOLT-4 GDSC1; GDSC2 4.0228 8.5844 1.2495 11.0606
TUR GDSC1; GDSC2 4.0394 6.757 2.1593 5.4971
CTV-1 GDSC1; GDSC2 4.0502 7.5037 1.8025 7.6546
KG-1 GDSC1; GDSC2 4.0674 8.1141 1.5152 9.3594
Loucy GDSC1; GDSC2 4.0824 6.3046 2.4068 3.9063
MOLT-16 GDSC1; GDSC2 4.1098 8.1403 1.5337 9.1439
Karpas-620 GDSC1; GDSC2 4.1216 10.5038 0.3737 15.7126
LP-1 GDSC1; GDSC2 4.124 6.456 2.3624 4.086
JVM-3 GDSC1; GDSC2 4.1273 15.2318 -1.9758 25.532
MV4-11 GDSC1; GDSC2 4.1315 12.5184 -0.6203 20.4398
ALL-PO GDSC1; GDSC2 4.1382 8.0141 1.6165 8.5756
P12-Ichikawa GDSC1; GDSC2 4.2069 8.0489 1.6492 8.2149
Reh GDSC1; GDSC2 4.2075 13.358 -0.9785 21.7296
BC-3 GDSC2 4.2261 7.7566 1.8054 7.2514
SUP-T1 GDSC1; GDSC2 4.2316 6.8281 2.2567 4.4961
WIL2 NS GDSC1; GDSC2 4.3005 8.122 1.6805 7.8104
A3/Kawakami GDSC1; GDSC2 4.3142 5.3578 2.9642 0.5541
IM-9 GDSC1; GDSC2 4.3577 6.4031 2.535 2.6456
JSC-1 GDSC1; GDSC2 4.3618 6.6908 2.4051 3.3747
H9 GDSC1; GDSC2 4.366 7.0634 2.2334 4.3652
TK [Human B-cell lymphoma] GDSC1; GDSC2 4.3687 7.9054 1.833 6.7426
RC-K8 GDSC1; GDSC2 4.3732 6.1254 2.669 1.891
YT GDSC1; GDSC2 4.3761 8.5872 1.5077 8.6694
HEL GDSC1; GDSC2 4.4159 5.6767 2.8831 0.795
KMOE-2 GDSC1; GDSC2 4.4456 7.2566 2.1937 4.4431
OCI-Ly19 GDSC1; GDSC2 4.4587 10.313 0.7226 12.9817
AMO1 GDSC1; GDSC2 4.4709 11.625 0.0847 16.284
VAL GDSC1; GDSC2 4.4743 9.4557 1.1543 10.512
L-428 GDSC1; GDSC2 4.4771 7.498 2.1003 4.9291
Hs 445 GDSC1; GDSC2 4.5012 8.7149 1.5338 8.2327
JJN-3 GDSC1; GDSC2 4.5099 6.0858 2.7594 1.2525
EoL-1 GDSC1; GDSC2 4.5138 9.3032 1.257 9.8262
CCRF-CEM GDSC1; GDSC2 4.5182 9.407 1.2096 10.0905
NOMO-1 GDSC1; GDSC2 4.5296 9.7258 1.0621 10.9109
Granta-519 GDSC1; GDSC2 4.5344 6.5408 2.5754 2.1468
EB2 GDSC1; GDSC2 4.5522 11.425 0.2444 15.2798
MOLT-13 GDSC1; GDSC2 4.5576 6.5746 2.5734 2.1232
HC-1 GDSC1; GDSC2 4.5827 18.2918 -3.1401 27.7595
NKM-1 GDSC1; GDSC2 4.5876 13.0122 -0.5131 18.7898
SK-MM-2 GDSC1; GDSC2 4.5916 7.2333 2.2958 3.5877
BC-1 GDSC1; GDSC2 4.594 9.2275 1.3503 9.1016
ALL-SIL GDSC1; GDSC2 4.6172 6.6719 2.5635 2.089
P31/FUJ GDSC1; GDSC2 4.6388 5.8033 2.9329 0.4243
SIG-M5 GDSC2 4.6453 11.6379 0.2087 15.2746
KM-H2 GDSC1; GDSC2 4.6633 10.736 0.6647 12.8033
OCI-AML-3 GDSC1; GDSC2 4.6852 14.5746 -1.2126 21.4279
OCI-AML-2 GDSC1; GDSC2 4.6935 8.9935 1.5317 7.8264
Sc-1 GDSC1 4.7158 16.2487 -3.5373 20.548
RPMI-8226 GDSC1; GDSC2 4.7221 9.2566 1.4249 8.3868
L-363 GDSC1; GDSC2 4.7814 9.691 1.2563 9.2297
BL-41 GDSC1; GDSC2 4.8255 7.2452 2.4263 2.5036
QIMR-WIL GDSC1; GDSC2 4.8425 21.9917 -4.778 30.8023
CRO-AP2 GDSC1; GDSC2 4.8957 12.0621 0.1839 14.7539
BE-13 GDSC1; GDSC2 4.9451 6.9942 2.5971 1.5076
U-698-M GDSC1; GDSC2 4.9832 10.6788 0.9191 10.6831
ME1 GDSC1; GDSC2 4.9882 6.4326 2.8407 0.5016
KCL-22 GDSC1; GDSC2 5.0041 7.1634 2.5558 1.6312
Karpas-299 GDSC1; GDSC2 5.0293 7.5792 2.3914 2.3985
MN-60 GDSC1; GDSC2 5.1224 8.8758 1.8634 5.0911
Karpas-231 GDSC1; GDSC2 5.1289 6.8274 2.7497 0.7125
VL51 GDSC1; GDSC2 5.2057 9.0209 1.8473 5.0366
Ramos.2G6.4C10 GDSC1; GDSC2 5.2578 6.6169 2.8798 0.2647
OPM-2 GDSC1; GDSC2 5.3327 7.2108 2.6897 0.7768
DB GDSC1; GDSC2 5.3508 6.8162 2.8439 0.3109
BV-173 GDSC1; GDSC2 5.3511 7.3092 2.6597 0.8702
MY-M12 GDSC2 5.3601 7.5064 2.586 1.1469
U266B1 GDSC1; GDSC2 5.4085 10.8647 1.1155 8.7191
CML-T1 GDSC1; GDSC2 5.4184 7.0953 2.7689 0.4743
SUP-M2 GDSC1; GDSC2 5.4424 14.2541 -0.4935 16.6742
SU-DHL-8 GDSC1; GDSC2 5.4808 7.0386 2.8138 0.3296
ST486 GDSC1; GDSC2 5.6742 7.4605 2.7362 0.4382
DEL GDSC1; GDSC2 5.6917 25.0585 -5.6401 30.6715
K-562 GDSC1; GDSC2 5.7079 7.1886 2.8451 0.1926
L-540 GDSC1; GDSC2 5.7172 10.0087 1.7008 4.99
DND-41 GDSC1; GDSC2 5.7625 7.4614 2.7697 0.3224
DG-75 GDSC1; GDSC2 5.7628 13.5395 0.0764 13.3548
MEG-01 GDSC1; GDSC2 5.8186 7.9541 2.6117 0.7176
Ku812 GDSC1; GDSC2 5.9769 8.0856 2.627 0.5853
Raji GDSC1; GDSC2 6.0218 14.6653 -0.288 14.5113
LAMA-84 GDSC1; GDSC2 6.0771 7.8269 2.7575 0.2466
KOPN-8 GDSC1; GDSC2 6.0824 17.183 -1.4645 19.1907
LC4-1 GDSC1; GDSC2 6.1059 8.443 2.5465 0.7493
HDLM-2 GDSC1; GDSC2 6.5445 8.3979 2.728 0.1829
ROS-50 GDSC1; GDSC2 7.4201 17.7847 -0.8459 14.2059
⏷ Show the Full List of 168 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FLO-1 GDSC1; GDSC2 2.8273 17.2188 -4.0429 34.1332
OACM5.1 C GDSC1; GDSC2 3.2786 6.1009 1.8962 9.1164
OACP4 C GDSC1; GDSC2 3.4564 8.8363 0.676 15.9216
KYAE-1 GDSC1; GDSC2 3.6953 10.927 -0.1742 19.6213
KYSE-220 GDSC1; GDSC2 3.9188 7.1984 1.8559 7.6452
KYSE-50 GDSC1; GDSC2 4.2139 7.0858 2.1215 5.3432
SK-GT-4 GDSC1; GDSC2 4.3608 11.5742 0.0264 16.8521
TE-12 GDSC1; GDSC2 4.3699 12.5196 -0.4354 18.9983
ESO-51 GDSC1; GDSC2 4.4092 11.9756 -0.1356 17.5108
ESO-26 GDSC1; GDSC2 5.0033 12.1166 0.2349 14.247
HCE-4 GDSC1; GDSC2 5.717 14.0313 -0.192 14.7137
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2 2.4912 10.1725 -0.8181 26.1816
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-12 GDSC1; GDSC2 2.1051 10.6086 -1.3793 29.5791
NB69 GDSC1; GDSC2 2.4586 7.3742 0.538 19.8635
SJNB-17 GDSC1; GDSC2 2.9888 8.8849 0.2581 19.596
NB1 GDSC1; GDSC2 3.2043 6.5051 1.6312 10.9921
NB(TU)1 GDSC1; GDSC2 3.2635 8.0326 0.9177 15.1178
SJNB-6 GDSC1; GDSC2 3.4574 6.2109 1.9887 8.0236
SK-N-MC-IXC GDSC1; GDSC2 3.7285 5.4504 2.5746 3.6597
SK-N-DZ GDSC1; GDSC2 3.8576 7.8718 1.4765 10.1236
SK-N-BE(2)-M17 GDSC1; GDSC2 3.8599 7.038 1.8909 7.5749
NH-12 GDSC1; GDSC2 3.96 7.7418 1.6186 8.9981
SiMa GDSC1; GDSC2 3.9766 7.4597 1.77 8.0314
MHH-NB-11 GDSC2 4.1144 8.748 1.2377 10.9351
TGW GDSC1; GDSC2 4.1223 6.3679 2.4032 3.8463
CHP-134 GDSC2 4.1566 6.8458 2.1977 5.0243
SJNB-13 GDSC1; GDSC2 4.184 6.4899 2.3859 3.8249
SJNB-10 GDSC1; GDSC2 4.2381 8.7958 1.3059 10.1917
SK-N-FI GDSC1; GDSC2 4.2711 10.3328 0.5727 14.266
Kelly GDSC1; GDSC2 4.3515 7.4941 2.019 5.6666
KP-N-RT-BM-1 GDSC2 4.4158 7.1746 2.2131 4.4026
CHP-212 GDSC1; GDSC2 4.4208 11.7067 0.0064 16.7964
IMR-5 GDSC1; GDSC2 4.4819 9.2319 1.269 9.83
KP-N-YN GDSC1; GDSC2 4.4927 7.3628 2.1739 4.4681
SK-N-AS GDSC1; GDSC2 4.6426 6.9105 2.4721 2.533
SJNB-5 GDSC1; GDSC2 4.6902 10.9442 0.5822 13.1826
SJNB-14 GDSC1; GDSC2 4.9535 7.3274 2.4599 2.1559
GOTO GDSC1; GDSC2 5.2681 8.2371 2.2341 2.8703
SK-N-SH GDSC1; GDSC2 5.2811 12.3875 0.2998 13.292
LA-N-6 GDSC1; GDSC2 5.2986 10.0132 1.4452 7.1086
CHP-126 GDSC1; GDSC2 5.4383 7.2518 2.7187 0.612
SJNB-7 GDSC1; GDSC2 5.5003 11.1226 1.0533 8.8773
KP-N-YS GDSC2 5.5669 7.5604 2.6557 0.736
GI-ME-N GDSC1; GDSC2 5.6017 13.2245 0.1177 13.4957
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1; GDSC2 3.682 12.8437 -1.1424 23.8022
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YMB-1-E GDSC2 -4.0096 7.7953 -6.2271 60.0786
Evsa-T GDSC1; GDSC2 -3.6334 5.6403 -5.0077 60.2619
MDA-MB-415 GDSC1; GDSC2 -1.8774 7.7799 -3.9781 51.0255
HCC70 GDSC1; GDSC2 -0.1589 12.7666 -4.5423 43.9346
HCC2157 GDSC1; GDSC2 0.025 6.4178 -1.4214 38.3215
MDA-MB-330 GDSC1; GDSC2 1.2918 7.2104 -0.495 29.3277
CAMA-1 GDSC1; GDSC2 1.5651 5.3074 0.6484 22.6273
BT-549 GDSC1; GDSC2 1.6324 15.7172 -4.3345 37.9369
HDQ-P1 GDSC1; GDSC2 2.0362 7.0353 0.3089 22.6064
HCC202 GDSC1 2.1374 5.8319 -0.2949 9.9734
EFM-19 GDSC1; GDSC2 2.3241 8.4351 -0.1074 23.6406
MDA-MB-361 GDSC1; GDSC2 2.8642 6.4882 1.3428 13.8288
MDA-MB-175-VII GDSC1; GDSC2 2.8706 5.7373 1.7201 11.4859
COLO 824 GDSC1; GDSC2 2.9359 6.2461 1.5269 12.4707
AU565 GDSC1; GDSC2 2.949 9.9888 -0.3272 22.5776
CAL-148 GDSC2 3.0268 7.9233 0.7708 16.7413
HCC1569 GDSC1; GDSC2 3.2021 11.9623 -1.0985 25.0268
HCC1806 GDSC1; GDSC2 3.346 6.3873 1.8092 9.4648
UACC-812 GDSC2 3.4543 9.4807 0.3521 17.7373
HCC1395 GDSC1; GDSC2 3.4614 21.1952 -5.4987 35.0289
Hs 578T GDSC1; GDSC2 3.4695 15.1423 -2.4658 28.7558
MDA-MB-453 GDSC1; GDSC2 3.6112 7.0901 1.6732 9.5703
BT-474 GDSC1; GDSC2 3.6339 7.2809 1.596 9.9852
EFM-192A GDSC1; GDSC2 3.6829 8.4745 1.0399 13.1981
UACC-893 GDSC1; GDSC2 3.7019 6.6281 1.9739 7.4607
T-47D GDSC1; GDSC2 3.8405 12.6253 -0.905 22.4239
MDA-MB-468 GDSC1; GDSC2 4.0025 13.0741 -0.9992 22.3593
HCC1419 GDSC1; GDSC2 4.0956 6.5492 2.2986 4.5283
DU4475 GDSC1; GDSC2 4.1596 7.0008 2.1251 5.4387
HCC1143 GDSC1; GDSC2 4.1759 12.5194 -0.586 20.1727
ZR-75-30 GDSC1; GDSC2 4.2221 9.0205 1.1836 10.9491
HCC38 GDSC1; GDSC2 4.3564 8.4696 1.551 8.4575
HCC1954 GDSC1; GDSC2 4.3783 10.3369 0.6512 13.5706
HCC2218 GDSC1; GDSC2 4.3966 9.8612 0.8989 12.1537
JIMT-1 GDSC1; GDSC2 4.5065 8.9857 1.4063 8.9714
HCC1187 GDSC1; GDSC2 4.572 12.2066 -0.1264 17.0552
BT-20 GDSC1; GDSC2 4.5759 7.8903 1.9792 5.4445
MCF-7 GDSC1; GDSC2 4.6167 11.5008 0.255 15.0669
OCUB-M GDSC1; GDSC2 4.6347 6.8334 2.5019 2.3861
HCC1937 GDSC1; GDSC2 4.7717 12.4033 -0.0744 16.3148
HCC1428 GDSC1; GDSC2 4.7947 6.5182 2.7204 1.1163
MRK-nu-1 GDSC1; GDSC2 4.9823 6.5648 2.7877 0.6846
BT-483 GDSC1; GDSC2 5.0275 11.2007 0.6975 11.7889
HCC1599 GDSC1; GDSC2 5.0478 13.0182 -0.1739 16.1276
MDA-MB-157 GDSC1; GDSC2 5.1869 7.8743 2.3478 2.4078
CAL-120 GDSC1; GDSC2 5.2102 13.3634 -0.2253 15.9901
CAL-85-1 GDSC1; GDSC2 5.2418 11.6505 0.6287 11.6837
HCC1500 GDSC1; GDSC2 5.327 6.8284 2.8304 0.354
MDA-MB-436 GDSC1; GDSC2 5.3583 14.4734 -0.6612 17.5909
MFM-223 GDSC1; GDSC2 5.3825 10.6896 1.1812 8.4099
MDA-MB-231 GDSC1; GDSC2 5.4956 7.835 2.517 1.2994
CAL-51 GDSC1; GDSC2 9.1686 22.2161 -1.8111 14.868
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-336MG GDSC1; GDSC2 0.8556 11.6151 -3.0245 38.286
YH-13 GDSC1; GDSC2 1.0401 9.3298 -1.7453 34.6722
GaMG GDSC1; GDSC2 1.2356 10.4273 -2.0905 34.8395
SW1088 GDSC1; GDSC2 1.6908 12.446 -2.6618 34.621
MOG-G-CCM GDSC1; GDSC2 2.1098 19.7038 -5.8998 38.7339
Becker GDSC1; GDSC2 2.1704 9.1318 -0.5907 26.355
D-423MG GDSC1; GDSC2 2.2046 10.838 -1.4035 29.32
LNZTA3WT4 GDSC1 2.468 4.3507 0.6223 2.4965
H4 GDSC1; GDSC2 2.6417 15.1842 -3.1852 32.8811
SNB-75 GDSC1; GDSC2 2.8013 8.7055 0.1849 20.5766
D-542MG GDSC1; GDSC2 3.0151 10.2292 -0.3906 22.6563
SK-MG-1 GDSC1; GDSC2 3.2149 9.9425 -0.078 20.5765
SW1783 GDSC1; GDSC2 3.2547 12.9832 -1.5648 26.5624
D-502MG GDSC1; GDSC2 3.336 8.8124 0.5884 16.7611
MOG-G-UVW GDSC1; GDSC2 3.5149 12.0296 -0.8722 23.2118
M059J GDSC1; GDSC2 3.6172 7.8142 1.3169 11.7336
SF295 GDSC1; GDSC2 3.6239 12.4346 -0.9853 23.3536
D-566MG GDSC1; GDSC2 3.6564 10.8869 -0.1855 19.7858
8-MG-BA GDSC1; GDSC2 3.7721 6.1442 2.2661 5.4648
42-MG-BA GDSC1; GDSC2 3.9069 12.2714 -0.6752 21.2843
D-245MG GDSC2 4.0006 8.813 1.1195 11.922
SF539 GDSC1; GDSC2 4.0161 8.9488 1.064 12.1666
PFSK-1 GDSC1; GDSC2 4.0637 8.678 1.2342 11.0475
D283 Med GDSC1; GDSC2 4.0887 11.4196 -0.107 18.2142
GI-1 GDSC1; GDSC2 4.1143 9.1327 1.0475 12.0099
LN-18 GDSC1; GDSC2 4.1401 18.011 -3.3524 29.3398
U-118MG GDSC1; GDSC2 4.1798 12.1232 -0.3858 19.2725
D-247MG GDSC1; GDSC2 4.2033 12.6044 -0.6068 20.1902
Hs 683 GDSC1; GDSC2 4.2234 15.102 -1.8348 24.8222
KALS-1 GDSC1; GDSC2 4.3412 15.8497 -2.1141 25.4278
LN-405 GDSC1; GDSC2 4.4473 10.421 0.661 13.3458
NMC-G1 GDSC1; GDSC2 4.4908 9.6834 1.0549 11.0433
U-251MG GDSC1; GDSC2 4.6316 9.687 1.1538 10.1508
GB-1 GDSC1; GDSC2 4.6669 8.7682 1.6218 7.3563
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 4.7145 11.1543 0.497 13.5767
T98G GDSC1; GDSC2 4.7248 12.1111 0.0347 15.901
KINGS-1 GDSC1; GDSC2 4.7307 11.8368 0.1739 15.198
A-172 GDSC1; GDSC2 4.7472 10.8595 0.6648 12.605
D-263MG GDSC1; GDSC2 5.0037 9.9427 1.2864 8.5856
SF126 GDSC1; GDSC2 5.0505 13.4435 -0.3805 17.0713
D-392MG GDSC1; GDSC2 5.0974 11.1883 0.7521 11.3418
Onda 10 GDSC1; GDSC2 5.2723 10.884 1.0168 9.5329
ONS-76 GDSC1; GDSC2 5.3427 7.3676 2.6331 0.9751
KNS-81-FD GDSC1; GDSC2 5.3458 15.3978 -1.1236 19.5117
DBTRG-05MG GDSC1; GDSC2 5.3642 13.5204 -0.1917 15.4852
AM-38 GDSC1; GDSC2 5.4518 7.3731 2.6784 0.7337
KNS-42 GDSC1; GDSC2 5.6659 10.4334 1.4778 6.2689
SF268 GDSC1; GDSC2 5.8136 11.9382 0.8712 9.2448
Onda 11 GDSC1; GDSC2 5.8784 20.483 -3.2324 25.152
U-87MG ATCC GDSC1; GDSC2 6.2431 20.1177 -2.7833 23.1638
CAS-1 GDSC1; GDSC2 6.2696 16.9117 -1.2008 17.8095
DK-MG GDSC1; GDSC2 6.3915 23.0323 -4.1068 26.2825
Daoy GDSC1; GDSC2 7.7801 17.4577 -0.4664 12.0311
YKG-1 GDSC1; GDSC2 7.8202 16.8595 -0.1669 10.6935
LN-229 GDSC1; GDSC2 7.8332 16.5223 -0.0054 9.9707
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 2.2948 4.637 1.6903 13.7141
TGBC1TKB GDSC1; GDSC2 3.3438 10.5317 -0.2648 21.0726
ETK-1 GDSC1; GDSC2 3.4611 10.3433 -0.0734 19.8159
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AN3-CA GDSC1; GDSC2 1.9336 8.0381 -0.2739 25.8329
KLE GDSC1; GDSC2 2.4853 14.8987 -3.1776 33.3144
MFE-280 GDSC1; GDSC2 3.6848 10.7633 -0.1008 19.3004
ESS-1 GDSC1; GDSC2 3.774 7.4562 1.6184 9.4751
RL95-2 GDSC1; GDSC2 4.6226 9.7033 1.1395 10.2533
MFE-319 GDSC1; GDSC2 4.6933 8.7326 1.6564 7.0983
EN GDSC1; GDSC2 4.8127 8.0598 2.0501 4.5886
MFE-296 GDSC1; GDSC2 5.4874 8.052 2.425 1.6957
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-26A GDSC1; GDSC2 -2.903 8.6787 -5.4263 55.3906
A-498 GDSC1; GDSC2 -1.593 12.0099 -5.5802 49.6738
CAL-54 GDSC1; GDSC2 -1.302 9.164 -3.9883 48.1904
KTCTL-140 GDSC1; GDSC2 -0.1648 10.5936 -3.5124 42.9251
UO-31 GDSC1; GDSC2 0.2446 11.2036 -3.4062 41.1823
RXF 393L GDSC1; GDSC2 0.2959 7.5723 -1.6543 37.6225
KMRC-1 GDSC1; GDSC2 0.5673 8.6013 -1.8587 36.9301
Caki-1 GDSC1; GDSC2 1.1481 11.9049 -2.893 36.9853
NCC021 GDSC1; GDSC2 1.5115 32.8474 -12.9754 44.4877
OS-RC-2 GDSC1; GDSC2 1.5165 13.805 -3.491 36.894
LB996-RCC GDSC1; GDSC2 1.7965 11.8428 -2.2682 33.2974
KTCTL-13 GDSC1; GDSC2 1.8042 12.1635 -2.4197 33.6584
A-704 GDSC1; GDSC2 2.2887 14.3181 -3.0593 33.6321
HA7-RCC GDSC1; GDSC2 2.452 11.9729 -1.7483 29.6304
BFTC-909 GDSC1; GDSC2 2.7689 7.2892 0.8604 17.003
ACHN GDSC1; GDSC2 2.8038 9.666 -0.2916 22.8807
786-O GDSC1; GDSC2 3.1659 9.6591 0.0224 20.2361
LB2241-RCC GDSC1; GDSC2 3.3397 11.0639 -0.5342 22.3008
VMRC-RCZ GDSC1; GDSC2 3.57 16.666 -3.1445 30.2627
KTCTL-195 GDSC1; GDSC2 3.7097 17.4971 -3.4451 30.6169
TK-10 GDSC1; GDSC2 3.8472 10.8129 0.0047 18.3306
BB65-RCC GDSC1; GDSC2 3.9327 10.5287 0.214 17.0461
LB1047-RCC GDSC1; GDSC2 4.1132 14.4122 -1.5784 24.2314
SW156 GDSC1; GDSC2 4.4242 9.991 0.8555 12.3301
RCC10RGB GDSC1; GDSC2 4.5279 18.3716 -3.223 28.0987
KTCTL-1M GDSC1; GDSC2 4.8034 14.8251 -1.2465 21.2676
KTCTL-21 GDSC1; GDSC2 4.9494 15.3311 -1.3861 21.4402
NCC010 GDSC1; GDSC2 4.983 19.8168 -3.5854 27.9534
769-P GDSC1; GDSC2 5.0585 17.5529 -2.4032 24.5967
SW13 GDSC1; GDSC2 5.1494 11.8268 0.4794 12.667
SN12C GDSC1; GDSC2 5.3547 15.9612 -1.394 20.5231
KMRC-20 GDSC1; GDSC2 6.9998 16.0622 -0.306 12.6997
VMRC-RCW GDSC2 7.3257 17.6583 -0.8472 14.4136
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LoVo GDSC1; GDSC2 -1.0008 9.0837 -3.6468 46.6419
C2BBe1 GDSC1; GDSC2 1.2274 6.5026 -0.2312 28.4532
SW48 GDSC1; GDSC2 1.8228 5.8559 0.6604 21.5302
SNU-81 GDSC1; GDSC2 2.245 15.8453 -3.8584 35.38
LS513 GDSC1 2.4926 4.6107 0.5203 3.1319
NCI-H508 GDSC1; GDSC2 2.7221 10.0771 -0.5677 24.3754
SK-CO-1 GDSC1; GDSC2 2.8553 7.2803 0.9415 16.2514
SNU-1040 GDSC1 3.433 4.8258 0.8713 0.2786
SNU-C5 GDSC1; GDSC2 3.4355 6.5413 1.8059 9.2303
CaR-1 GDSC1; GDSC2 3.452 7.0812 1.5496 10.7751
NCI-H747 GDSC1; GDSC2 3.6112 10.422 0.01 18.9713
COLO 320HSR GDSC1; GDSC2 3.7241 11.0937 -0.2341 19.822
SW948 GDSC1; GDSC2 3.7315 6.9474 1.8382 8.2278
COLO205 GDSC1; GDSC2 3.9501 10.4618 0.261 16.7576
GP5d GDSC1; GDSC2 3.985 6.8632 2.0689 6.1754
LS411N GDSC1; GDSC2 4.0183 5.938 2.5388 3.2499
HT-29 GDSC1; GDSC2 4.0414 8.8665 1.124 11.7515
SNU-175 GDSC2 4.0864 7.5822 1.7904 7.6687
T84 GDSC1; GDSC2 4.092 8.5955 1.2962 10.6091
RCM-1 [Human ESC] GDSC1; GDSC2 4.1667 9.952 0.6819 13.939
LS123 GDSC1; GDSC2 4.2222 16.5723 -2.5688 27.0869
RKO GDSC1; GDSC2 4.2327 6.5206 2.403 3.6288
DiFi GDSC1; GDSC2 4.2394 8.2303 1.584 8.531
SNU-283 GDSC2 4.245 9.9712 0.7317 13.5062
LS180 GDSC1; GDSC2 4.2804 7.5159 1.96 6.1724
SW1463 GDSC1; GDSC2 4.3157 7.9715 1.7643 7.2725
HCT 116 GDSC1; GDSC2 4.3861 10.0878 0.7797 12.8452
HCC2998 GDSC1; GDSC2 4.4465 8.4489 1.6244 7.8171
HT-55 GDSC1; GDSC2 4.5323 9.4862 1.181 10.2229
SW1417 GDSC1; GDSC2 4.5888 11.9373 0.0191 16.3114
HT115 GDSC1; GDSC2 4.5905 7.2715 2.2775 3.6929
SNU-407 GDSC1; GDSC2 4.6002 7.9697 1.9575 5.5234
SW626 GDSC1; GDSC2 4.6525 9.8638 1.0826 10.5091
CCK-81 GDSC1; GDSC2 4.6878 8.2685 1.8733 5.842
SNU-C1 GDSC1; GDSC2 4.8611 11.5595 0.4048 13.7122
SW1116 GDSC1; GDSC2 4.904 9.7199 1.3261 8.5685
SW620 GDSC1; GDSC2 4.9751 9.1482 1.6443 6.6027
SNU-61 GDSC1; GDSC2 4.9826 7.3081 2.4835 2.0021
COLO 678 GDSC1; GDSC2 4.9916 9.1604 1.6493 6.5424
LS1034 GDSC1; GDSC2 5.068 6.8918 2.6974 0.9557
CW-2 GDSC1; GDSC2 5.3628 7.615 2.5437 1.312
KM12 GDSC1; GDSC2 5.5227 7.315 2.7295 0.5316
NCI-H716 GDSC1; GDSC2 5.5438 20.4071 -3.447 26.4036
SNU-C2B GDSC1; GDSC2 5.7507 12.7345 0.4534 11.5228
HCT 15 GDSC1; GDSC2 5.8215 13.1031 0.3249 12.0219
MDST8 GDSC1; GDSC2 6.1826 16.2785 -0.955 17.0215
CL-11 GDSC1; GDSC2 6.2727 14.8625 -0.2132 13.6658
SW837 GDSC1; GDSC2 6.6961 18.9207 -1.8759 19.3997
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 5.3626 7.078 2.7527 0.5519
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-2 GDSC1; GDSC2 -0.6002 11.2821 -4.2625 45.3566
SNU-387 GDSC1; GDSC2 3.5341 9.1117 0.6019 16.1066
HuH-1 GDSC1; GDSC2 3.9042 8.0417 1.428 10.2967
SNU-398 GDSC1; GDSC2 4.4451 6.8248 2.3945 3.2857
Huh-7 GDSC1; GDSC2 4.4759 8.8324 1.4591 8.7297
JHH-7 GDSC1; GDSC2 4.5239 8.8236 1.497 8.3989
Hep-G2/C3A GDSC1; GDSC2 4.5441 6.7389 2.4925 2.5757
Hep 3B2.1-7 GDSC1; GDSC2 4.5515 13.8629 -0.9622 20.7774
SNU-423 GDSC1; GDSC2 4.9395 20.4845 -3.9513 28.8932
SK-HEP-1 GDSC1; GDSC2 5.3236 6.7413 2.8603 0.2837
SNU-449 GDSC1; GDSC2 5.8482 12.5744 0.5937 10.6155
JHH-6 GDSC1; GDSC2 5.8813 17.5634 -1.7948 20.7946
HLE GDSC1; GDSC2 5.9939 14.3374 -0.1496 13.9383
JHH-1 GDSC1; GDSC2 6.6862 21.3176 -3.0495 23.0408
JHH-4 GDSC1; GDSC2 6.8442 18.9412 -1.7828 18.7897
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 186 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC78 GDSC1; GDSC2 0.936 11.4428 -2.8653 37.6917
NCI-H292 GDSC1; GDSC2 0.9628 7.2922 -0.8583 32.1511
NCI-H2085 GDSC1; GDSC2 1.4739 13.8798 -3.5665 37.165
NCI-H1648 GDSC1; GDSC2 1.5274 7.3656 -0.338 27.6925
EPLC-272H GDSC1; GDSC2 1.815 8.4206 -0.5711 27.5752
NCI-H2171 GDSC2 1.8623 7.0199 0.1501 24.1512
SBC-1 GDSC1; GDSC2 2.0109 7.1237 0.2421 23.0463
RERF-LC-MS GDSC1; GDSC2 2.1334 8.9167 -0.5187 26.1812
NCI-H446 GDSC1; GDSC2 2.1564 18.6979 -5.3577 37.9482
NCI-H1666 GDSC1; GDSC2 2.1695 10.6222 -1.3281 29.1813
HCC44 GDSC1; GDSC2 2.1802 8.2668 -0.1563 24.3844
NCI-H1703 GDSC1; GDSC2 2.2355 7.4762 0.282 22.0167
COR-L95 GDSC1 2.2715 6.4308 -0.4908 10.9944
NCI-H1975 GDSC1; GDSC2 2.2886 8.118 0.0163 23.1679
NCI-H187 GDSC1 2.3061 9.9674 -2.2105 21.2983
NCI-H1304 GDSC1 2.3723 4.3689 0.5593 3.1077
EBC-1 GDSC1; GDSC2 2.4607 13.789 -2.6456 32.1323
NCI-H69 GDSC1; GDSC2 2.5852 6.2587 1.202 15.6096
NCI-H838 GDSC1; GDSC2 2.6641 10.3539 -0.7562 25.3572
NCI-H460 GDSC1; GDSC2 2.7078 4.5503 2.1428 9.4333
CAL-12T GDSC1; GDSC2 2.7651 7.9823 0.5128 18.9647
NCI-H322M GDSC1; GDSC2 2.8503 7.4188 0.8683 16.6916
NCI-H647 GDSC1; GDSC2 2.9818 14.5118 -2.5589 30.3726
DMS 273 GDSC1; GDSC2 3.0223 19.3117 -4.924 35.1669
EMC-BAC-1 GDSC1; GDSC2 3.0727 8.4045 0.5701 17.6651
NCI-H1755 GDSC1; GDSC2 3.0812 11.2164 -0.8277 24.3247
NCI-H720 GDSC1; GDSC2 3.1204 5.6071 2.0073 8.8955
NCI-H1993 GDSC1; GDSC2 3.2508 10.6742 -0.4136 22.033
NCI-H250 GDSC2 3.3475 12.827 -1.4094 25.8065
NCI-H2122 GDSC1; GDSC2 3.3823 6.1493 1.9582 8.4263
EMC-BAC-2 GDSC1; GDSC2 3.5496 10.6754 -0.1669 20.0054
HCC827 GDSC1; GDSC2 3.5813 8.9776 0.7072 15.3869
NCI-H520 GDSC1; GDSC2 3.5881 12.7688 -1.1816 24.217
NCI-H1734 GDSC2 3.6105 7.4993 1.4686 10.8677
NCI-H3122 GDSC1; GDSC2 3.6502 6.1144 2.189 6.2506
LCLC-103H GDSC1; GDSC2 3.6553 7.7808 1.3638 11.3455
NCI-H1623 GDSC1; GDSC2 3.6721 8.4476 1.0447 13.1999
HCC366 GDSC1; GDSC2 3.7191 8.6905 0.961 13.5571
NCI-H1781 GDSC1; GDSC2 3.724 9.4459 0.5882 15.6427
BEN GDSC1; GDSC2 3.7466 8.3287 1.1631 12.2992
COR-L311 GDSC2 3.7584 7.8152 1.4279 10.7153
NCI-H1437 GDSC1; GDSC2 3.7784 6.2091 2.2388 5.6189
NCI-H1694 GDSC1; GDSC2 3.802 7.7863 1.4761 10.2714
NCI-H2030 GDSC1; GDSC2 3.83 13.6787 -1.4394 24.4955
NCI-H1355 GDSC1; GDSC2 3.8444 10.3194 0.2485 17.1121
LOU-NH91 GDSC1; GDSC2 3.8877 8.5077 1.1842 11.7975
A-549 GDSC1; GDSC2 3.8901 12.9308 -1.0176 22.7382
NCI-H2196 GDSC2 3.8957 9.7349 0.5802 15.2605
RERF-LC-Sq1 GDSC1; GDSC2 3.9516 7.9748 1.4972 9.7575
NCI-H1563 GDSC1; GDSC2 4.0132 11.2458 -0.0797 18.2863
NCI-H2342 GDSC1; GDSC2 4.0189 10.6314 0.2306 16.7279
COR-L303 GDSC2 4.034 7.0246 2.0253 6.351
NCI-H2291 GDSC1; GDSC2 4.0493 22.0891 -5.4626 33.6808
SW1573 GDSC1; GDSC2 4.0564 9.9278 0.6093 14.6248
NCI-H526 GDSC1; GDSC2 4.0569 8.7403 1.1982 11.2767
NCI-H1944 GDSC1; GDSC2 4.0636 14.8625 -1.8425 25.2623
COR-L32 GDSC1; GDSC2 4.0798 10.1151 0.5344 14.9688
NCI-H2081 GDSC1; GDSC2 4.089 11.9581 -0.3747 19.4644
NCI-H2087 GDSC1; GDSC2 4.0896 6.4658 2.3346 4.3244
NCI-H345 GDSC1; GDSC2 4.1146 5.8082 2.6608 2.3565
COR-L23 GDSC1; GDSC2 4.1186 9.6012 0.819 13.3018
NCI-H2170 GDSC1; GDSC2 4.1359 11.2591 0.0096 17.5222
LC-2/ad GDSC1; GDSC2 4.1689 11.006 0.1609 16.6823
Lu-139 GDSC1 4.1827 5.8158 0.7989 0.1958
NCI-H1048 GDSC1; GDSC2 4.1927 9.4527 0.9485 12.3793
SBC-5 GDSC1; GDSC2 4.2144 11.7357 -0.1663 18.1626
LCLC-97TM1 GDSC1; GDSC2 4.2869 9.0098 1.2367 10.4804
NCI-H2373 GDSC1; GDSC2 4.3014 8.4222 1.5348 8.681
COR-L279 GDSC1; GDSC2 4.306 13.8678 -1.155 22.1667
Lu-99A GDSC1; GDSC2 4.3404 9.7448 0.9147 12.2026
NCI-H64 GDSC2 4.3435 13.72 -1.0522 21.7191
NCI-H1155 GDSC1; GDSC2 4.3448 11.791 -0.0933 17.4743
ABC-1 GDSC1; GDSC2 4.3507 9.815 0.8878 12.329
NCI-H2110 GDSC1; GDSC2 4.3572 11.2255 0.1963 16.0146
COLO 668 GDSC1; GDSC2 4.3657 7.9919 1.7892 7.0119
LC-1/sq GDSC1; GDSC2 4.3664 8.5152 1.5359 8.5245
NCI-H1573 GDSC1; GDSC2 4.3829 7.4714 2.0509 5.4111
NCI-H2461 GDSC1; GDSC2 4.4073 14.831 -1.555 23.3892
NCI-H2135 GDSC1; GDSC2 4.4081 7.1995 2.1964 4.4998
NCI-H1792 GDSC1; GDSC2 4.4171 8.5084 1.575 8.1766
NCI-H2869 GDSC1; GDSC2 4.4188 7.7409 1.9462 5.9592
SHP-77 GDSC1; GDSC2 4.4333 6.5277 2.5232 2.5856
NCI-H2731 GDSC1; GDSC2 4.4421 7.3704 2.1378 4.7778
COR-L105 GDSC1; GDSC2 4.4466 14.2694 -1.2451 22.1504
HOP-62 GDSC1; GDSC2 4.459 10.1054 0.8248 12.4162
LXF 289 GDSC1; GDSC2 4.4728 16.1612 -2.1656 25.2616
NCI-H2009 GDSC1; GDSC2 4.4946 11.8456 -0.0064 16.6718
NCI-H2023 GDSC1; GDSC2 4.5111 10.5565 0.6415 13.2956
UMC-11 GDSC1; GDSC2 4.5128 8.1239 1.8262 6.4751
NCI-H2141 GDSC1; GDSC2 4.5215 11.2558 0.3049 15.0463
Lu-134-A GDSC1; GDSC2 4.5439 11.7209 0.0923 16.0637
NCI-H1436 GDSC1; GDSC2 4.5447 10.2387 0.8221 12.2247
NCI-H1838 GDSC1; GDSC2 4.5672 8.4894 1.6879 7.1787
HOP-92 GDSC1; GDSC2 4.5964 15.6164 -1.7982 23.7601
NCI-H596 GDSC1; GDSC2 4.5968 9.6499 1.1472 10.2688
NCI-H847 GDSC1; GDSC2 4.6365 11.4162 0.3113 14.731
NCI-H835 GDSC1; GDSC2 4.6365 13.936 -0.9334 20.4475
Lu-135 GDSC1; GDSC2 4.6584 8.0252 1.969 5.3425
NCI-H2810 GDSC1; GDSC2 4.6616 9.5173 1.2572 9.4892
NCI-H2804 GDSC1; GDSC2 4.6954 7.3306 2.3136 3.3121
NCI-H3255 GDSC1; GDSC2 4.7154 14.3931 -1.0996 20.9151
NCI-H1915 GDSC1; GDSC2 4.7673 8.0939 2.006 4.9229
NCI-H740 GDSC2 4.7723 11.3705 0.433 13.8155
NCI-H2595 GDSC1; GDSC2 4.7846 9.6091 1.298 8.9842
NCI-H2369 GDSC1; GDSC2 4.789 10.8177 0.7152 12.2353
NCI-H2444 GDSC1; GDSC2 4.7957 12.4188 -0.0643 16.2081
SK-MES-1 GDSC1; GDSC2 4.8024 16.2479 -1.9525 23.7749
NCI-H1963 GDSC2 4.8026 7.0461 2.501 2.1587
NCI-H23 GDSC1; GDSC2 4.8345 7.2517 2.4284 2.4797
NCI-H1693 GDSC2 4.8363 10.0448 1.1236 9.8968
PC-14 GDSC1; GDSC2 4.8635 11.1676 0.5978 12.6931
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2 4.8696 10.5549 0.8999 11.0407
SBC-3 GDSC1; GDSC2 4.8883 8.9913 1.6623 6.6696
NCI-H1299 GDSC1; GDSC2 4.897 12.2985 0.069 15.319
COR-L321 GDSC1; GDSC2 4.8972 10.7947 0.803 11.5102
EKVX GDSC1; GDSC2 4.9035 18.8812 -3.1821 27.1293
NCI-H2818 GDSC1; GDSC2 4.9116 10.7602 0.8299 11.3313
Lu-65 GDSC1; GDSC2 4.915 7.6645 2.2906 3.0878
HCC33 GDSC2 4.9172 14.0463 -0.7757 19.1554
NCI-H1836 GDSC1; GDSC2 4.9349 10.0665 1.1808 9.328
DMS 114 GDSC1; GDSC2 4.9565 7.9626 2.1807 3.6162
LB647-SCLC GDSC1; GDSC2 4.9661 12.0619 0.2349 14.3333
Ms-1 GDSC1; GDSC2 4.977 8.7461 1.8338 5.5189
NCI-H748 GDSC2 4.9777 7.8723 2.2336 3.3084
NCI-H1105 GDSC1; GDSC2 4.9982 7.0916 2.5829 1.5133
SK-LU-1 GDSC1; GDSC2 5.0215 14.8338 -1.0862 20.1212
NCI-H358 GDSC1; GDSC2 5.0408 12.3321 0.1566 14.5506
NCI-H1869 GDSC1; GDSC2 5.0855 17.5969 -2.4044 24.5382
DMS 53 GDSC1; GDSC2 5.0878 7.2711 2.5525 1.5525
Calu-3 GDSC1; GDSC2 5.1143 8.0251 2.2427 3.0435
NCI-H82 GDSC1; GDSC2 5.1318 7.0007 2.6832 0.9571
NCI-H1092 GDSC1; GDSC2 5.1321 6.9974 2.6846 0.9512
IST-SL2 GDSC1; GDSC2 5.15 11.8177 0.4842 12.6408
NCI-H1341 GDSC1; GDSC2 5.1674 13.2117 -0.182 15.8876
IA-LM GDSC1; GDSC2 5.174 7.4328 2.5278 1.5703
NCI-H226 GDSC1; GDSC2 5.1874 10.7321 1.0325 9.6218
PaCa-3 GDSC1; GDSC2 5.1879 12.4064 0.2252 13.8741
ChaGo-K-1 GDSC1; GDSC2 5.2038 15.6287 -1.3422 20.6769
NCI-H2803 GDSC1; GDSC2 5.2142 9.903 1.4431 7.281
NCI-H727 GDSC1; GDSC2 5.2175 7.4143 2.5565 1.3988
NCI-H1876 GDSC1; GDSC2 5.2183 11.6955 0.5908 11.934
NCI-H510A GDSC2 5.2254 6.9427 2.7467 0.6584
NCI-H441 GDSC1; GDSC2 5.2266 10.4227 1.2058 8.5829
SW1271 GDSC1; GDSC2 5.2602 8.3023 2.2012 3.0495
CPC-N GDSC1; GDSC2 5.265 12.599 0.186 13.896
NCI-H524 GDSC1; GDSC2 5.2749 7.5957 2.5098 1.544
NCI-H2029 GDSC1; GDSC2 5.2778 6.9963 2.7484 0.6166
NCI-H2227 GDSC1; GDSC2 5.2821 8.5819 2.0901 3.5973
NCI-H146 GDSC1; GDSC2 5.2865 9.9285 1.4771 6.9534
NCI-H513 GDSC1; GDSC2 5.2894 12.4353 0.2825 13.361
VMRC-LCD GDSC1; GDSC2 5.312 7.5041 2.5647 1.2725
NCI-H2066 GDSC1; GDSC2 5.3135 12.019 0.5005 12.1979
A-427 GDSC1; GDSC2 5.3216 11.1702 0.9132 9.9954
RERF-LC-KJ GDSC1; GDSC2 5.3849 14.2282 -0.5222 16.9295
COR-L88 GDSC1; GDSC2 5.405 7.4895 2.6129 1.0011
NCI-H1688 GDSC1; GDSC2 5.4353 11.7003 0.7362 10.7071
NCI-H2172 GDSC1; GDSC2 5.441 7.8788 2.4736 1.5319
NCI-H209 GDSC1; GDSC2 5.449 7.6812 2.557 1.1806
DMS 79 GDSC1; GDSC2 5.483 7.2031 2.7549 0.4802
Lu-165 GDSC1; GDSC2 5.4926 7.1163 2.7904 0.3816
NCI-H1651 GDSC1; GDSC2 5.5111 10.2805 1.4537 6.671
NCI-H2228 GDSC1; GDSC2 5.5348 21.4084 -3.9498 27.6272
NCI-H2405 GDSC1; GDSC2 5.5516 13.8483 -0.2188 15.1948
NCI-H1793 GDSC1; GDSC2 5.6179 17.7765 -2.0926 22.3642
NCI-H650 GDSC1; GDSC2 5.6573 7.5293 2.7043 0.5325
NCI-H2795 GDSC1; GDSC2 5.7064 17.8942 -2.0851 22.1468
NCI-H1581 GDSC1; GDSC2 5.7513 7.3847 2.7926 0.2779
NCI-H841 GDSC1; GDSC2 5.782 11.9011 0.8683 9.32
NCI-H810 GDSC1; GDSC2 5.8585 7.3225 2.8528 0.1464
Calu-6 GDSC1; GDSC2 5.8628 8.1176 2.5683 0.8284
LK-2 GDSC1; GDSC2 5.8644 12.2419 0.761 9.7225
NCI-H1650 GDSC1; GDSC2 5.9466 22.7391 -4.2955 27.5694
IST-SL1 GDSC1; GDSC2 6.0201 7.9037 2.7095 0.3606
NCI-H211 GDSC1; GDSC2 6.0237 11.7227 1.1027 7.6459
NCI-H522 GDSC1; GDSC2 6.0641 8.9429 2.3354 1.5228
NCI-H1435 GDSC1; GDSC2 6.0675 16.8574 -1.3166 18.6713
KNS-62 GDSC1; GDSC2 6.1594 13.5023 0.3577 11.1924
NCI-H2591 GDSC1; GDSC2 6.2547 15.6123 -0.5843 15.336
NCI-H2347 GDSC1; GDSC2 6.3504 21.27 -3.2703 24.2975
NCI-H2722 GDSC1; GDSC2 6.6001 15.5274 -0.3126 13.4732
NCI-H661 GDSC1; GDSC2 6.6433 14.7136 0.099 11.5209
NCI-H1568 GDSC1; GDSC2 6.9351 21.4495 -2.9356 22.2437
HCC15 GDSC1; GDSC2 6.9714 16.9014 -0.7203 14.5133
NCI-H290 GDSC1; GDSC2 7.0433 15.951 -0.2262 12.2705
NCI-H1770 GDSC1; GDSC2 7.357 23.5881 -3.677 23.4524
NCI-H196 GDSC1; GDSC2 7.8414 22.2895 -2.7109 19.9329
⏷ Show the Full List of 186 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 5.7866 16.7589 -1.4696 19.8414
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-6 GDSC1; GDSC2 2.6537 5.4554 1.6576 12.6035
EC-GI-10 GDSC1; GDSC2 3.2911 7.3008 1.3067 12.7269
TE-11 GDSC1; GDSC2 3.3362 5.9886 2.0004 8.2935
KYSE-520 GDSC1; GDSC2 3.4046 6.9548 1.5739 10.76
T.T GDSC1; GDSC2 3.4896 7.9015 1.1704 12.9702
TE-15 GDSC1 3.7435 7.0058 0.1541 3.3012
OE33 GDSC1; GDSC2 3.8347 10.8897 -0.0436 18.6017
OE19 GDSC1; GDSC2 3.8841 10.1113 0.3836 16.2987
KYSE-140 GDSC1; GDSC2 3.9086 5.6702 2.5935 3.1485
KYSE-270 GDSC1; GDSC2 3.9977 8.4059 1.3188 10.7127
TE-10 GDSC1; GDSC2 4.0364 6.7621 2.1548 5.5313
KYSE-150 GDSC1; GDSC2 4.0964 8.5443 1.3248 10.4286
KYSE-450 GDSC1; GDSC2 4.1359 8.4104 1.4201 9.7624
KYSE-510 GDSC1; GDSC2 4.1525 10.0976 0.5989 14.4298
TE-8 GDSC1; GDSC2 4.1549 10.4635 0.4193 15.3855
TE-1 GDSC1; GDSC2 4.2777 11.2308 0.133 16.5382
OE21 GDSC1; GDSC2 4.3151 11.184 0.1848 16.1809
TE-5 GDSC1; GDSC2 4.5395 9.877 0.9954 11.2665
KYSE-180 GDSC1; GDSC2 4.5496 7.1397 2.3132 3.5626
COLO 680N GDSC1; GDSC2 4.6617 6.874 2.4991 2.3611
KYSE-410 GDSC1; GDSC2 4.8169 8.6041 1.7986 6.0227
TE-9 GDSC1; GDSC2 4.9899 9.4301 1.521 7.2789
KYSE-70 GDSC1; GDSC2 5.4388 9.6119 1.717 5.3564
TE-4 GDSC1; GDSC2 5.5604 17.0395 -1.7725 21.417
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IGROV-1 GDSC1; GDSC2 0.3669 6.1248 -0.9415 35.1769
A2780 GDSC1; GDSC2 1.5181 5.2971 0.6048 23.0583
JHOS-4 GDSC1; GDSC2 1.73 9.9628 -1.4034 30.9943
OVTOKO GDSC1; GDSC2 1.8422 7.5394 -0.1187 25.4611
RMG-I GDSC1; GDSC2 2.7592 13.2095 -2.0983 29.737
JHOS-2 GDSC1; GDSC2 2.893 11.9735 -1.3663 26.9573
OC 314 GDSC1; GDSC2 2.9886 9.5469 -0.0725 21.2539
OVCAR-3 GDSC1; GDSC2 3.6305 11.2277 -0.3769 20.7474
OVK18 GDSC1; GDSC2 3.6471 7.4885 1.5031 10.5201
TOV-21G GDSC1; GDSC2 3.7785 6.3733 2.158 6.1207
OV56 GDSC1; GDSC2 3.7809 6.997 1.8515 8.0182
OVISE GDSC1; GDSC2 3.9009 8.8257 1.0364 12.6285
OVCAR-5 GDSC1; GDSC2 4.1338 9.7642 0.7498 13.6488
FU-OV-1 GDSC1; GDSC2 4.2276 11.2889 0.0657 17.0039
DOV13 GDSC1; GDSC2 4.3667 8.8919 1.3523 9.6111
OAW42 GDSC1; GDSC2 4.7955 12.8912 -0.297 17.3014
EFO-21 GDSC1; GDSC2 5.0484 19.5115 -3.3829 27.3143
TYK-nu GDSC1; GDSC2 5.0814 9.95 1.3346 8.154
OVKATE GDSC1; GDSC2 5.2207 11.5118 0.6811 11.4528
Caov-3 GDSC2 5.5333 14.8993 -0.7433 17.5877
Caov-4 GDSC1; GDSC2 5.5947 15.0856 -0.7902 17.605
TOV-112D GDSC1; GDSC2 5.6438 8.0319 2.5062 1.2131
OV-90 GDSC1; GDSC2 5.8011 11.6049 1.0192 8.4872
SK-OV-3 GDSC1; GDSC2 5.8218 15.2605 -0.7142 16.7911
OVCAR-8 GDSC1; GDSC2 5.9912 14.4354 -0.1984 14.168
OAW28 GDSC1; GDSC2 6.1234 16.8139 -1.2559 18.3237
EFO-27 GDSC1; GDSC2 6.4365 18.5389 -1.8731 19.908
Kuramochi GDSC1; GDSC2 6.6103 19.6675 -2.2989 20.9612
OVCAR-4 GDSC1; GDSC2 7.2883 16.7846 -0.4608 12.8504
ES-2 GDSC1; GDSC2 7.7384 18.8111 -1.124 14.7348
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PL4 GDSC1; GDSC2 3.4994 8.2261 1.0161 13.8536
PaTu 8902 GDSC1; GDSC2 3.7348 7.3332 1.6491 9.3887
DAN-G GDSC1; GDSC2 3.8599 8.1778 1.3265 11.023
BxPC-3 GDSC1; GDSC2 4.0326 10.6729 0.2206 16.7423
Hs 766T GDSC1; GDSC2 4.0367 13.0367 -0.9534 22.0834
SU.86.86 GDSC1; GDSC2 4.063 10.7807 0.1907 16.8125
SUIT-2 GDSC1; GDSC2 4.3345 7.0854 2.2024 4.6106
HPAC GDSC1; GDSC2 4.3848 13.6092 -0.965 21.2132
Panc 08.13 GDSC1; GDSC2 4.4153 11.8929 -0.09 17.2775
PSN1 GDSC1; GDSC2 4.4419 6.5351 2.5249 2.5622
Capan-2 GDSC2 4.5532 12.3028 -0.1882 17.4415
CFPAC-1 GDSC1; GDSC2 4.6707 14.3946 -1.1344 21.1619
Capan-1 GDSC1; GDSC2 4.7047 10.8599 0.6341 12.8704
KP-2 GDSC1; GDSC2 4.7709 9.9424 1.1276 9.9864
MIA PaCa-2 GDSC1; GDSC2 4.7879 7.9971 2.0637 4.5555
Panc 03.27 GDSC1; GDSC2 4.8216 17.5901 -2.6041 25.7405
Panc 02.03 GDSC1; GDSC2 4.8282 13.7424 -0.6925 18.9725
YAPC GDSC1; GDSC2 4.9139 10.7115 0.8551 11.1881
Panc 10.05 GDSC1; GDSC2 5.0464 11.0749 0.7716 11.3486
AsPC-1 GDSC2 5.2018 12.5411 0.1695 14.159
HuP-T3 GDSC1; GDSC2 5.2306 13.8599 -0.4534 16.9781
MZ-PC-1 GDSC1; GDSC2 5.3069 12.8919 0.0733 14.3549
Panc 04.03 GDSC1; GDSC2 5.3649 15.3572 -1.0896 19.3347
KP-1N GDSC1; GDSC2 5.4111 11.6357 0.7508 10.6801
KP-3 GDSC1; GDSC2 5.4314 9.7353 1.6561 5.7017
PaTu 8988t GDSC1; GDSC2 5.6082 17.3468 -1.8883 21.7077
QGP-1 GDSC1; GDSC2 5.6647 14.2839 -0.3507 15.5486
HPAF-II GDSC1; GDSC2 5.7271 16.8111 -1.5383 20.2213
HuP-T4 GDSC1; GDSC2 6.0104 18.2472 -2.036 21.3348
SW1990 GDSC1; GDSC2 6.2839 14.014 0.197 11.7324
KP-4 GDSC1; GDSC2 6.6301 16.6151 -0.8108 15.5368
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC1; GDSC2 4.3123 7.9806 1.7574 7.3212
NCI-H2452 GDSC1; GDSC2 4.8476 22.3332 -4.9441 31.1027
IST-Mes1 GDSC1; GDSC2 4.8549 10.0747 1.122 9.8332
MSTO-211H GDSC1; GDSC2 5.2125 17.8887 -2.4521 24.3929
MPP 89 GDSC1; GDSC2 5.3749 14.6946 -0.7575 17.9611
NCI-H2052 GDSC2 5.5936 13.4311 0.0125 14.0577
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; GDSC2 -3.1852 6.315 -4.774 57.8002
VCaP GDSC1; GDSC2 4.4509 10.5069 0.6214 13.5516
NCI-H660 GDSC2 4.695 6.8801 2.5149 2.2379
PC-3 GDSC1; GDSC2 5.0454 16.3549 -1.8199 22.7544
22Rv1 GDSC1; GDSC2 5.1134 12.6286 0.0639 14.8389
DU145 GDSC1; GDSC2 5.6012 10.9102 1.2173 7.7958
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2 4.7262 6.546 2.6751 1.3955
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UACC-62 GDSC1; GDSC2 1.6289 14.1168 -3.5441 36.6366
LOX-IMVI GDSC1; GDSC2 2.7295 7.0717 0.933 16.7127
RPMI-7951 GDSC1; GDSC2 2.7473 10.4057 -0.7095 24.8926
VMRC-MELG GDSC1; GDSC2 2.7896 8.3737 0.3398 19.811
MZ-MEL-2 GDSC1; GDSC2 2.872 10.4144 -0.6059 24.0551
A-388 GDSC1; GDSC2 2.9731 7.6725 0.8495 16.4066
WM115 GDSC1; GDSC2 2.9867 14.8124 -2.705 30.742
COLO 792 GDSC1; GDSC2 3.2844 7.8986 1.0022 14.5629
SK-MEL-31 GDSC1; GDSC2 3.3914 13.966 -1.9424 27.4129
Hs 938.T GDSC1; GDSC2 3.4051 12.3815 -1.1388 24.5807
CP50-MEL-B GDSC1; GDSC2 3.4207 9.1473 0.4911 17.041
COLO 783 GDSC1; GDSC2 3.5127 7.3778 1.4507 11.2113
RVH-421 GDSC1; GDSC2 3.6874 18.272 -3.8508 31.5653
DJM-1 GDSC1; GDSC2 3.7008 7.03 1.7734 8.71
IGR-1 GDSC1; GDSC2 3.9135 6.1508 2.3651 4.5231
MZ-MEL-7 GDSC1; GDSC2 4.0893 9.6158 0.7894 13.5437
A2058 GDSC2 4.099 9.018 1.0927 11.8255
WM35 GDSC1; GDSC2 4.1467 8.1791 1.5417 9.0065
SK-MEL-28 GDSC1; GDSC2 4.1879 16.6286 -2.6242 27.329
A101D GDSC1; GDSC2 4.2005 13.9217 -1.2647 22.8606
M14 GDSC1; GDSC2 4.2863 14.2995 -1.3854 23.0863
G-361 GDSC1; GDSC2 4.3688 12.7023 -0.527 19.4085
A-431 GDSC1; GDSC2 4.4565 12.036 -0.1294 17.3608
COLO 679 GDSC1; GDSC2 4.543 7.8672 1.9686 5.5718
SK-MEL-30 GDSC1; GDSC2 4.5547 6.0274 2.8061 0.9886
SK-MEL-3 GDSC1; GDSC2 4.6139 9.746 1.1125 10.4274
LB2518-MEL GDSC1; GDSC2 4.6198 7.1543 2.3489 3.242
Mel JuSo GDSC1; GDSC2 4.6442 6.3063 2.7344 1.2144
CHL-1 GDSC1; GDSC2 4.7029 15.2141 -1.5162 22.5128
WM1552C GDSC1; GDSC2 4.7474 9.8411 1.1603 9.8533
HMV-II GDSC1; GDSC2 4.7824 8.7207 1.7211 6.5398
IST-MEL1 GDSC1; GDSC2 4.8564 14.5044 -1.0477 20.3653
Mel Ho GDSC1; GDSC2 4.8642 19.8935 -3.7163 28.5245
MeWo GDSC1; GDSC2 4.8667 12.71 -0.1552 16.469
IPC-298 GDSC1; GDSC2 4.8903 11.6409 0.3861 13.7404
CP66-MEL GDSC1; GDSC2 4.9074 12.1103 0.1688 14.8015
WM793 GDSC1; GDSC2 4.9562 11.7745 0.3681 13.68
LB373-MEL-D GDSC1; GDSC2 5.0399 6.546 2.8194 0.5374
SK-MEL-2 GDSC1; GDSC2 5.0638 8.0641 2.197 3.3603
SH-4 GDSC1; GDSC2 5.1226 13.0997 -0.1596 15.8863
A-375 GDSC1; GDSC2 5.152 10.1616 1.2806 8.3154
WM278 GDSC1; GDSC2 5.1719 16.4258 -1.7594 22.2524
GAK GDSC1; GDSC2 5.1823 6.5268 2.8833 0.2859
451Lu GDSC1; GDSC2 5.1989 7.1344 2.6605 0.9884
G-mel GDSC1; GDSC2 5.3241 10.8336 1.075 9.1085
Hs 940.T GDSC1; GDSC2 5.3323 13.3254 -0.1195 15.2193
MMAc-SF GDSC1; GDSC2 5.3423 15.9637 -1.4044 20.5901
IGR-37 GDSC1; GDSC2 5.3762 17.3176 -2.0463 22.75
SK-MEL-1 GDSC1; GDSC2 5.5718 7.0593 2.8406 0.2396
COLO 800 GDSC1; GDSC2 5.9374 15.7974 -0.8933 17.286
COLO 829 GDSC1; GDSC2 6.0531 16.2642 -1.0385 17.6252
SK-MEL-5 GDSC1; GDSC2 6.5256 21.4308 -3.2212 23.8221
HT-144 GDSC1; GDSC2 6.8307 18.7829 -1.7157 18.5819
WT2-iPS GDSC1; GDSC2 7.5113 17.0432 -0.441 12.378
UACC-257 GDSC1; GDSC2 7.7089 19.7116 -1.5685 16.4312
SK-MEL-24 GDSC1; GDSC2 8.8195 25.0798 -3.3868 20.2033
EquiPSC Line K2 GDSC1; GDSC2 4.3581 9.0819 1.2532 10.213
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 3.231 6.1494 1.8317 9.6613
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-401 GDSC1; GDSC2 1.6174 7.1151 -0.1319 26.3978
Rh41 GDSC1; GDSC2 2.4589 5.0329 1.6722 13.2075
Rh18 GDSC1 2.9734 9.2457 -1.3622 14.6906
TE 441.T GDSC2 3.465 8.539 0.8316 15.0669
STS-0421 GDSC1; GDSC2 3.5354 9.6607 0.3286 17.5706
SW982 GDSC1; GDSC2 3.6694 11.3907 -0.4266 20.861
G-402 GDSC1; GDSC2 3.679 12.6488 -1.0474 23.4424
EW-8 GDSC1; GDSC2 3.7873 5.8659 2.4138 4.5136
VA-ES-BJ GDSC1; GDSC2 3.8417 7.7461 1.5267 9.8601
MES-SA GDSC1; GDSC2 3.9455 7.3139 1.8188 7.808
Rh30 GDSC1; GDSC2 4.3774 8.9436 1.3348 9.6888
KYM-1 GDSC1; GDSC2 4.4728 10.9317 0.4284 14.5265
A-204 GDSC1; GDSC2 4.6436 17.9308 -2.9123 27.0177
SW684 GDSC1; GDSC2 5.0801 10.9203 0.8694 10.744
MFH-ino GDSC1; GDSC2 5.2106 13.8466 -0.4614 17.0599
RD GDSC1; GDSC2 5.2398 13.1062 -0.0786 15.2353
SK-UT-1 GDSC1; GDSC2 5.2926 9.8933 1.4974 6.829
GCT GDSC1; GDSC2 5.4616 12.9555 0.1507 13.6365
HT-1080 GDSC1; GDSC2 5.4764 8.9441 2.0383 3.5822
SK-LMS-1 GDSC1; GDSC2 5.6905 14.4963 -0.4355 15.8712
Hs 633.T GDSC1; GDSC2 6.0503 16.1389 -0.9797 17.3968
SW872 GDSC1; GDSC2 6.2352 17.136 -1.3336 18.3855
RKN GDSC1; GDSC2 6.9498 18.3263 -1.4146 17.2676
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
23132/87 GDSC1; GDSC2 0.7008 9.7189 -2.2575 37.3213
HGC-27 GDSC2 1.0948 5.1135 0.2445 26.8426
NCI-N87 GDSC1; GDSC2 1.1198 7.3725 -0.7402 31.0341
Fu97 GDSC1; GDSC2 2.1353 8.8695 -0.4937 26.0668
HSC-39 GDSC1; GDSC2 3.0689 6.0508 1.7413 10.7203
IM95 GDSC1; GDSC2 3.4629 7.0612 1.5684 10.6283
AGS GDSC1; GDSC2 3.5239 6.5923 1.8519 8.6967
SCH GDSC1; GDSC2 3.5646 13.725 -1.6788 26.0645
SNU-5 GDSC1; GDSC2 3.6086 9.3648 0.536 16.253
MKN1 GDSC1; GDSC2 3.794 8.0729 1.3275 11.191
GCIY GDSC2 3.8867 8.808 1.0342 12.7203
MKN45 GDSC1; GDSC2 3.9045 7.6592 1.6176 9.1439
SK-GT-2 GDSC1; GDSC2 4.0426 8.8984 1.1091 11.8355
SNU-1 GDSC1; GDSC2 4.234 6.2987 2.5076 3.0186
Hs 746.T GDSC1; GDSC2 4.3193 11.3694 0.0961 16.6146
KATO III GDSC1; GDSC2 4.3394 7.2229 2.1403 4.9683
RF-48 GDSC1; GDSC2 4.5537 9.9994 0.9458 11.5124
OCUM-1 GDSC1; GDSC2 4.7107 9.6241 1.2397 9.4806
TMK-1 GDSC1; GDSC2 4.7737 10.8173 0.7045 12.3289
ECC12 GDSC2 4.8933 6.1428 2.9101 0.3491
ECC10 GDSC1; GDSC2 5.0905 10.3174 1.1657 9.0848
MKN28 GDSC1; GDSC2 5.2383 9.6209 1.5902 6.411
NUGC-3 GDSC1; GDSC2 5.2411 14.5409 -0.7796 18.3603
RERF-GC-1B GDSC1; GDSC2 5.2729 12.2993 0.3368 13.1236
NUGC-4 GDSC1; GDSC2 5.3868 14.0649 -0.441 16.5669
SNU-16 GDSC1; GDSC2 5.4151 6.6339 2.9311 0.126
MKN7 GDSC1; GDSC2 5.4176 14.2528 -0.5107 16.8052
TGBC11TKB GDSC1; GDSC2 5.5013 8.4202 2.2782 2.3527
SNG-M GDSC1; GDSC2 5.3711 7.1057 2.7458 0.5679
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8305C GDSC1; GDSC2 2.9716 12.4458 -1.5351 27.3043
K5 GDSC1; GDSC2 3.6876 9.3665 0.5987 15.6871
ASH-3 GDSC1; GDSC2 3.7102 7.3234 1.6349 9.5417
CAL-62 GDSC1; GDSC2 4.0917 7.1762 1.9926 6.3961
KMH-2 GDSC1; GDSC2 4.3499 8.7244 1.4221 9.2385
ML-1 [Human leukemia] GDSC2 4.605 9.6981 1.1295 10.3843
HTC-C3 GDSC1; GDSC2 4.611 15.0609 -1.5109 22.7202
CGTH-W-1 GDSC2 4.6832 8.8245 1.6058 7.4409
TT2609-C02 GDSC1; GDSC2 5.0528 7.6106 2.3904 2.3721
TT GDSC1; GDSC2 5.0682 14.2213 -0.7498 18.6395
B-CPAP GDSC1; GDSC2 5.2927 11.728 0.6263 11.587
8505C GDSC1; GDSC2 5.3759 7.6079 2.5527 1.263
IHH-4 GDSC1; GDSC2 5.5314 14.2057 -0.4066 16.0912
BHT-101 GDSC1; GDSC2 6.0035 17.8589 -1.851 20.7276
FTC-133 GDSC1; GDSC2 6.7077 20.3575 -2.5656 21.5958
WRO GDSC1; GDSC2 6.8973 16.8265 -0.7336 14.707
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BB49-HNC GDSC1; GDSC2 -1.1632 9.0215 -3.7836 47.4665
DOK GDSC1; GDSC2 1.5766 7.1308 -0.1789 26.7783
BB30-HNC GDSC1; GDSC2 2.7894 6.4527 1.2933 14.3739
JHU-029 GDSC1; GDSC2 2.8719 8.8111 0.1938 20.3014
BICR 10 GDSC1; GDSC2 2.8889 7.3535 0.9348 16.1817
KON GDSC1; GDSC2 3.1159 8.2673 0.6756 16.9464
PCI-38 GDSC1 3.1388 5.1994 0.6066 1.5777
NCI-H3118 GDSC1; GDSC2 3.1774 7.7589 0.9819 15.0041
JHU-022 GDSC1; GDSC2 3.1926 6.7018 1.5231 11.6967
HO-1-N-1 GDSC1; GDSC2 3.2952 6.977 1.472 11.7058
JHU-011 GDSC1; GDSC2 3.421 5.7077 2.2106 6.7295
PCI-15A GDSC1; GDSC2 3.4251 5.3565 2.3893 5.5923
HSC-2 GDSC1; GDSC2 3.4335 6.3188 1.9154 8.5502
Detroit 562 GDSC1; GDSC2 3.4564 7.1733 1.5071 11.0245
HO-1-u-1 GDSC1; GDSC2 3.4735 7.35 1.4328 11.4312
OSC-19 GDSC1; GDSC2 3.4836 7.6751 1.2785 12.3393
SAS GDSC1; GDSC2 3.6244 6.5285 1.9632 7.7298
SAT [Human HNSCC] GDSC1; GDSC2 3.7498 10.3318 0.1669 17.7929
CAL-33 GDSC1; GDSC2 3.881 8.1601 1.3515 10.8178
HSC-4 GDSC1; GDSC2 4.1106 11.2096 0.0145 17.5658
UPCI-SCC-090 GDSC1; GDSC2 4.1503 7.1725 2.0357 6.0015
SCC-15 GDSC1; GDSC2 4.2188 12.5697 -0.5774 20.0219
Ca9-22 GDSC1; GDSC2 4.2747 7.9885 1.7271 7.5887
SCC-4 GDSC1; GDSC2 4.2793 7.9095 1.7687 7.3275
PCI-06A GDSC1; GDSC2 4.4518 8.3005 1.6997 7.3574
HSC-3 GDSC1; GDSC2 4.5406 11.6584 0.1206 15.931
CAL-27 GDSC1; GDSC2 4.6239 17.045 -2.4871 25.8682
KOSC-2 GDSC1; GDSC2 4.6344 8.5319 1.7128 6.8901
SCC-9 GDSC1; GDSC2 4.6576 18.2043 -3.0375 27.3181
SKN-3 GDSC1; GDSC2 4.7175 8.7021 1.6871 6.8693
PCI-04B GDSC1; GDSC2 4.7302 8.3821 1.8472 5.9106
BHY GDSC1; GDSC2 4.9605 12.8727 -0.1662 16.2969
BICR 78 GDSC1; GDSC2 4.9744 9.9442 1.2661 8.7619
LB771-HNC GDSC1; GDSC2 5.2995 10.821 1.0648 9.2145
BICR 22 GDSC1; GDSC2 5.5862 14.526 -0.5235 16.4861
OSC-20 GDSC1; GDSC2 5.7257 15.0645 -0.6867 16.8827
PE/CA-PJ15 GDSC1; GDSC2 5.7293 13.9407 -0.1397 14.4457
SCC-25 GDSC1; GDSC2 5.7467 7.979 2.5721 0.8934
BICR 31 GDSC2 5.8321 13.4681 0.1576 12.8553
PCI-30 GDSC1; GDSC2 6.136 14.143 0.0387 12.7734
FaDu GDSC1; GDSC2 7.2401 17.1294 -0.6534 13.744
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-29 GDSC1; GDSC2 2.9014 7.8531 0.697 17.5029
SW1710 GDSC1; GDSC2 3.9918 12.0284 -0.4864 20.23
HT-1197 GDSC1; GDSC2 4.0798 10.2104 0.4871 15.2227
BFTC-905 GDSC1; GDSC2 4.21 9.6929 0.8429 12.9335
KU-19-19 GDSC1; GDSC2 4.2247 7.225 2.0619 5.6794
TCCSUP GDSC1; GDSC2 4.2713 8.4153 1.5166 8.8604
SW780 GDSC1; GDSC2 4.6302 6.7307 2.5448 2.1675
J82 GDSC1; GDSC2 4.8713 8.3277 1.9622 4.9817
639V GDSC1; GDSC2 4.9074 13.1253 -0.3294 17.1792
UM-UC-3 GDSC1; GDSC2 5.2038 12.5199 0.1813 14.0564
RT-4 GDSC1; GDSC2 5.26 7.2231 2.653 0.9666
5637 GDSC1; GDSC2 5.3033 11.2388 0.8681 10.2765
647V GDSC1; GDSC2 5.8016 18.5547 -2.3396 22.7527
RT-112 GDSC1; GDSC2 6.1922 16.2022 -0.9114 16.8258
HT-1376 GDSC1; GDSC2 6.2632 17.152 -1.3217 18.2831
T24 GDSC1; GDSC2 6.5281 16.0291 -0.5992 14.8545
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW962 GDSC1; GDSC2 1.0258 14.8757 -4.4647 39.9373
BPH-1 GDSC1; GDSC2 1.0931 11.4733 -2.7332 36.8545
ACC-OV7 GDSC1; GDSC2 1.4005 14.1693 -3.7759 37.7558
CAL-39 GDSC1; GDSC2 1.6489 5.4852 0.6548 22.2511
SKN GDSC1; GDSC2 2.544 11.3165 -1.3408 27.9739
PA-1 GDSC2 2.9493 11.4531 -1.0582 25.7072
KGN GDSC1; GDSC2 3.0074 15.4111 -2.9867 31.3882
UWB1.289 GDSC1; GDSC2 3.1659 9.0236 0.34 18.615
OVCA420 GDSC1; GDSC2 3.3675 14.0285 -1.9934 27.6404
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 3.4515 6.1299 2.0244 7.816
OVMIU GDSC1; GDSC2 3.4744 6.9132 1.6517 10.0806
ME-180 GDSC1; GDSC2 3.7142 8.6487 0.9779 13.4724
SW954 GDSC1; GDSC2 3.8555 10.7235 0.0559 18.0549
Ca Ski GDSC1; GDSC2 3.9026 10.4586 0.2252 17.0714
PEO1 GDSC1; GDSC2 4.2053 8.8621 1.2491 10.6062
HEY GDSC1; GDSC2 4.2932 7.5831 1.9364 6.2862
NEC8 GDSC1; GDSC2 4.311 8.3398 1.5819 8.3776
LB831-BLC GDSC1; GDSC2 4.3119 9.6774 0.9267 12.2053
HEC-1 GDSC1; GDSC2 4.3371 6.2163 2.6077 2.2777
NCC-IT GDSC2 4.3509 8.6527 1.4578 9.0544
DSH1 GDSC1; GDSC2 4.4407 7.4211 2.113 4.9263
JHOS-3 GDSC1; GDSC2 4.5869 11.7768 0.0968 15.9344
C-4-I GDSC1; GDSC2 4.7615 14.1339 -0.9362 20.1493
DoTc2 4510 GDSC1; GDSC2 4.8209 6.8985 2.5743 1.7625
C-33 A GDSC1; GDSC2 4.9204 8.1262 2.0851 4.2034
NT2-D1 GDSC1; GDSC2 4.9818 16.539 -1.9594 23.3715
SiSo GDSC1; GDSC2 4.9939 12.0876 0.2423 14.2314
TC-YIK GDSC1; GDSC2 5.0384 11.7584 0.4345 13.1492
OVCA433 GDSC1; GDSC2 5.1781 16.894 -1.9861 23.0028
JAR GDSC1; GDSC2 5.2808 18.8739 -2.888 25.4983
OV17R GDSC1; GDSC2 5.5956 18.9009 -2.6634 24.1716
SW756 GDSC1; GDSC2 5.6095 13.5617 -0.0396 14.2328
SKG-IIIa GDSC1; GDSC2 5.903 15.9832 -1.008 17.822
HeLa GDSC1; GDSC2 5.968 15.3385 -0.6496 16.2068
MS751 GDSC1; GDSC2 6.0015 17.2815 -1.5703 19.7461
PWR-1E GDSC1; GDSC2 6.0506 13.3978 0.3362 11.5088
JEG-3 GDSC1; GDSC2 6.4425 18.5844 -1.891 19.9568
HT-3 GDSC1; GDSC2 7.5229 24.1478 -3.8315 23.5431
SiHa GDSC1; GDSC2 8.6695 23.9706 -2.9579 19.2528
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8527).
2 National Cancer Institute Drug Dictionary (drug id 751594).
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 Inhibition of cholesterol metabolism underlies synergy between mTOR pathway inhibition and chloroquine in bladder cancer cells. Oncogene. 2016 Aug 25;35(34):4518-28. doi: 10.1038/onc.2015.511. Epub 2016 Feb 8.