Details of the Drug

General Information of Drug (ID: DMX3FN4)

Drug Name
ISIS-APOCIII
Indication
Disease Entry ICD 11 Status REF
Atherosclerosis BD40 Phase 1 [1]
Hyperlipemia 5C80 Phase 1 [1]
Inflammation 1A00-CA43.1 Phase 1 [1]
Metabolic syndrome x 5C50-5D2Z Phase 1 [1]
Drug Type
Antisense drug
Cross-matching ID
TTD ID
D0F6KM
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ApoC-III messenger RNA (APOC3 mRNA) TTXOZQ1 APOC3_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Atherosclerosis
ICD Disease Classification BD40
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
ApoC-III messenger RNA (APOC3 mRNA) DTT APOC3 2.67E-01 0.1 0.59
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).