Details of the Drug

General Information of Drug (ID: DMXB20Y)

Drug Name
MDX-214
Synonyms CD89 monoclonal antibody (cancer, autoimmune disease), Medarex
Indication
Disease Entry ICD 11 Status REF
Autoimmune diabetes 5A10 Discontinued in Phase 1/2 [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
D08PXM

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Immunoglobulin alpha Fc receptor (FCAR) TTGUJAO FCAR_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019614)
2 A phase I, pharmacokinetic (PK) and pharmacodynamic (PD) study of MDX-214, a novel immune-mediated mechanism agent targeting the epithelial growth factor receptor (EGFR), in patients with advanced solid tumors. Journal of Clinical Oncology, Vol 24, No 18S (June 20 Supplement), 2006: 2523.