Details of the Drug

General Information of Drug (ID: DMXCQ5T)

Drug Name

fluciclovine F-18

Synonyms

18F-Ge-148; 18F fluciclovine; [18F]-FACBC; Anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic-acid; Anti-1-amino-3-F-18-fluorocyclobutane-1-carboxylic-acid; Anti-1-amino-3-fluorine-18-fluorocyclobutane-1-carboxylic acid; Anti-18-F-FACBC; Anti-18F-FABC; Anti-3-18F-FACBC; Anti-F-18-fluorocyclobutane-carboxylic-acid; Axumin; FACBC; Fluciclovine-F-18; GE-148; Ge-148-18F; Ge-148-F-18; Trans-1-amino-3-18F-fluorocyclobutanecarboxylic-acid

Indication

Disease Entry	ICD 11	Status	REF
Prostate cancer	2C82.0	Approved	[1]
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Affected Organisms

Humans and other mammals

ATC Code

V09IX12: fluciclovine F-18

V09IX: Other diagnostic radiopharmaceuticals for tumour detection

V09I: TUMOUR DETECTION

V09: DIAGNOSTIC RADIOPHARMACEUTICALS

V: VARIOUS

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C5H8FNO2
Canonical SMILES: C1C(CC1(C(=O)O)N)F
InChI: 1S/C5H8FNO2/c6-3-1-5(7,2-3)4(8)9/h3H,1-2,7H2,(H,8,9)/i6-1
InChIKey: NTEDWGYJNHZKQW-KWCOIAHCSA-N

Cross-matching ID

PubChem CID: 450601
ChEBI ID: CHEBI:134703
CAS Number: 222727-39-1
UNII: 38R1Q0L1ZE
DrugBank ID: DB13146
TTD ID: D03QIP

References

1	2016 FDA drug approvals. Nat Rev Drug Discov. 2017 Feb 2;16(2):73-76.