Details of the Drug

General Information of Drug (ID: DMXMQAT)

Drug Name
RG-7273
Synonyms RG 7273; RG7273
Indication
Disease Entry ICD 11 Status REF
Lipid metabolism disorder 5C52.Z Discontinued in Phase 1 [1]
Cross-matching ID
TTD ID
D03JQR

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
ATP-binding cassette transporter A1 (ABCA1) TTJW1GN ABCA1_HUMAN Inducer [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Lipid metabolism disorder
ICD Disease Classification 5C52.Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
ATP-binding cassette transporter A1 (ABCA1) DTT ABCA1 4.88E-01 -0.1 -0.33
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031594)
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 756).