Details of the Drug

General Information of Drug (ID: DMXW67H)

Drug Name
MX-6120
Synonyms Endothelin-1 antagonists (heart disease); ET-1 antagonists (heart disease), Maxia; Endothelin-1 antagonists (heart disease), Maxia
Indication
Disease Entry ICD 11 Status REF
Heart disease BA41-BA42 Terminated [1]
Cross-matching ID
TTD ID
D0NC1D

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Endothelin A receptor (EDNRA) TTKRD0G EDNRA_HUMAN Antagonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Heart disease
ICD Disease Classification BA41-BA42
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Endothelin A receptor (EDNRA) DTT EDNRA 3.19E-05 -2.69 -1.71
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018158)
2 Endothelin receptor antagonists in heart failure: current status and future directions. Drugs. 2004;64(10):1029-40.