Details of the Drug

General Information of Drug (ID: DMY3TAD)

Drug Name
Recombinant factor VIIa PEGylated liposomal
Synonyms Recombinant factor VIIa; Recombinant factor VIIa (PEGylated liposomal (NecLip), Hemophilia A) Recoly
Indication
Disease Entry ICD 11 Status REF
Factor VII deficiency 3B14 Phase 1/2 [1]
Cross-matching ID
TTD ID
D0HZ2A

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor VII (F7) TTF0EGX FA7_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Factor VII deficiency
ICD Disease Classification 3B14
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Coagulation factor VII (F7) DTT F7 2.52E-01 -0.03 -0.19
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Safety, pharmacokinetics and efficacy of factor VIIa formulated with PEGylated liposomes in haemophilia A patients with inhibitors to factor VIII--an open label, exploratory, cross-over, phase I/II study. Haemophilia. 2010 Nov;16(6):910-8.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2363).