Details of the Drug

General Information of Drug (ID: DMYB0DK)

Drug Name
AM-643
Synonyms FLAP inhibitor (topical, dermatological disorder), Amira; 5-lipoxygenase-activating protein inhibitor (topical, dermatological disorder), Amira
Indication
Disease Entry ICD 11 Status REF
Dermatological disease DA24.Y Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C36H39N4NaO4S
Canonical SMILES
CC1=CN=C(C=C1)COC2=CC3=C(C=C2)N(C(=C3SC(C)(C)C)CC(C)(C)C(=O)[O-])CC4=CC=C(C=C4)C5=NC=C(C=N5)OC.[Na+]
InChI
InChI=1S/C36H40N4O4S.Na/c1-23-8-13-26(37-18-23)22-44-27-14-15-30-29(16-27)32(45-35(2,3)4)31(17-36(5,6)34(41)42)40(30)21-24-9-11-25(12-10-24)33-38-19-28(43-7)20-39-33;/h8-16,18-20H,17,21-22H2,1-7H3,(H,41,42);/q;+1/p-1
InChIKey
UFKVTMVFNCOIKU-UHFFFAOYSA-M
Cross-matching ID
PubChem CID
46843035
ChEBI ID
CHEMBL1210423
CAS Number
1233114-34-5
TTD ID
D03NMM
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug

References

1 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.