Details of the Drug

General Information of Drug (ID: DMYIPKJ)

Drug Name
AT13148
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1 [1]
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 313.8
Logarithm of the Partition Coefficient (xlogp) 2.2
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C17H16ClN3O
IUPAC Name
(1S)-2-amino-1-(4-chlorophenyl)-1-[4-(1H-pyrazol-4-yl)phenyl]ethanol
Canonical SMILES
C1=CC(=CC=C1C2=CNN=C2)[C@@](CN)(C3=CC=C(C=C3)Cl)O
InChI
InChI=1S/C17H16ClN3O/c18-16-7-5-15(6-8-16)17(22,11-19)14-3-1-12(2-4-14)13-9-20-21-10-13/h1-10,22H,11,19H2,(H,20,21)/t17-/m0/s1
InChIKey
IIRWNGPLJQXWFJ-KRWDZBQOSA-N
Cross-matching ID
PubChem CID
24905401
CAS Number
1056901-62-2
TTD ID
D09IYM

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Rho-associated protein kinase (ROCK) TTMQO60 NOUNIPROTAC Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 4.7902 8.5844 1.7907 6.1419
EW-12 GDSC2 0.7793 3.7153 0.3493 24.5747
SaOS-2 GDSC2 1.8882 4.6305 1.2753 17.8232
CAL-72 GDSC2 2.0036 3.1323 1.9301 13.6115
CHSA8926 GDSC2 2.1871 6.575 0.6742 20.1444
SK-ES-1 GDSC2 2.2063 6.0024 0.9673 18.4004
HOS GDSC2 2.2403 3.5537 2.071 11.7634
CHSA0011 GDSC2 2.6987 4.2209 2.1233 6.494
ES8 GDSC2 2.8051 5.9311 1.565 12.7052
EW-22 GDSC2 3.3917 6.0846 1.9983 8.1766
EW-7 GDSC2 3.4446 5.2287 2.4687 5.0559
MHH-ES-1 GDSC2 3.4554 6.2356 1.9747 7.8912
CHSA0108 GDSC2 3.5032 7.7969 1.0069 11.1378
EW-18 GDSC2 3.6055 6.5605 1.9324 8.0004
ES6 GDSC2 3.6638 8.246 1.1387 12.7116
ES5 GDSC2 3.7679 6.9521 1.6216 6.7227
EW-24 GDSC2 3.783 6.263 2.2157 5.771
TC-71 GDSC2 3.8444 7.7703 1.5167 9.9474
MG-63 GDSC2 3.893 9.2481 0.8203 13.9324
HuO9 GDSC2 4.0212 6.7834 2.1336 5.715
SJSA-1 GDSC2 4.0991 8.8464 1.1777 11.3277
CADO-ES1 GDSC2 4.1299 7.1053 2.054 5.9563
EW-3 GDSC2 4.174 6.8637 2.201 4.9673
EW-16 GDSC2 4.257 8.119 1.651 8.1151
U2OS GDSC2 4.4321 9.144 1.2763 9.6419
U-CH2 GDSC2 4.4334 7.1032 1.984 3.2672
HuO-3N1 GDSC2 4.4767 11.9618 -0.0775 17.1079
EW-11 GDSC2 4.5256 9.4141 1.2114 10.0962
EW-1 GDSC2 4.7146 6.6569 2.6222 1.6682
ES7 GDSC2 4.7362 8.149 1.9606 5.2602
ES1 GDSC2 4.7621 8.297 1.9077 5.5169
CAL-78 GDSC2 4.9007 11.3465 0.5372 12.967
G-292 clone A141B1 GDSC2 4.9074 8.1752 2.0548 4.41
H-EMC-SS GDSC2 5.2989 10.9506 1.0027 9.5857
ES4 GDSC2 5.811 8.6718 2.3266 1.8006
A-673 GDSC2 5.9969 18.4576 -2.1489 21.775
NOS-1 [Human HNSCC] GDSC2 6.1738 8.4603 2.5676 0.653
SK-PN-DW GDSC2 6.226 8.0045 2.7498 0.2216
NY GDSC2 6.8196 9.1863 2.5546 0.4123
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 164 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC2 3.8649 6.4746 1.9199 4.6939
P31/FUJ GDSC2 -0.9763 2.7984 -1.237 43.8657
SUP-B8 GDSC2 -0.0972 2.0344 -0.1738 31.4648
SR GDSC2 -0.0799 2.4294 -0.1905 34.6698
WSU-DLCL2 GDSC2 0.1122 1.0752 0.1116 32.2131
Ku812 GDSC2 0.474 2.9776 0.3007 29.4599
JVM-3 GDSC2 0.4864 4.4206 -0.1294 31.4773
Kasumi-1 GDSC2 0.5064 1.9229 0.48 25.1577
SUP-T1 GDSC2 0.5801 13.6311 -4.2644 41.1741
SIG-M5 GDSC2 0.6653 1.2543 0.6652 23.429
IM-9 GDSC2 0.6847 5.2577 -0.2452 31.039
ML-2 GDSC2 0.753 4.9864 -0.0628 29.8915
NCI-H929 GDSC2 0.7588 7.2083 -1.0234 33.7246
VAL GDSC2 1.0442 3.4015 0.814 24.0659
BONNA-12 GDSC2 1.0728 4.2281 0.4691 22.6315
EM-2 GDSC2 1.1283 3.857 0.7631 23.9557
JSC-1 GDSC2 1.2263 2.6925 1.1709 21.3134
AMO1 GDSC2 1.4346 4.9933 0.6496 23.2406
JVM-2 GDSC2 1.4691 6.1068 0.192 25.5073
SU-DHL-16 GDSC2 1.5033 4.6374 0.7461 19.2795
RCH-ACV GDSC2 1.509 4.3437 0.8789 18.4877
P12-Ichikawa GDSC2 1.5145 4.5067 0.9349 21.3188
ST486 GDSC2 1.5209 4.6774 0.8721 21.6441
CRO-AP2 GDSC2 1.5413 3.0999 1.3797 15.4946
QIMR-WIL GDSC2 1.5468 4.8641 0.69 19.4304
OCI-Ly7 GDSC2 1.56 2.9042 1.4536 15.0077
Farage GDSC2 1.5737 5.5252 0.4148 20.8932
NK-92MI GDSC2 1.5917 3.1503 1.4196 15.0484
Loucy GDSC2 1.5958 5.993 0.3709 24.0692
RPMI-8402 GDSC2 1.7484 5.3102 0.8342 20.9242
JURL-MK1 GDSC2 1.8574 5.1009 1.0384 19.3221
Ramos.2G6.4C10 GDSC2 1.9278 6.1128 0.6442 21.2851
DoHH2 GDSC2 1.9399 3.182 1.7887 11.4478
GDM-1 GDSC2 1.9523 6.2876 0.5856 21.5139
JeKo-1 GDSC2 1.9529 4.6519 1.1954 14.877
SU-DHL-6 GDSC2 1.9846 6.1223 0.6953 20.783
P32/ISH GDSC2 2.0315 5.1841 1.1773 17.8301
Jurkat GDSC2 2.1249 7.3851 0.2232 22.7923
HH [Human lymphoma] GDSC2 2.195 14.1856 -3.0754 34.0119
Karpas-45 GDSC2 2.2114 6.4098 0.777 19.4764
CCRF-CEM GDSC2 2.2313 6.3414 0.8289 19.1075
THP-1 GDSC2 2.2877 5.7248 1.0064 14.8162
KMS-11 GDSC2 2.3196 3.5947 2.0399 8.3991
MM1.S GDSC2 2.3313 6.0024 1.0874 17.2403
BC-3 GDSC2 2.3489 4.3002 1.7509 10.0298
HT GDSC2 2.3916 8.0913 -0.0689 20.5781
BV-173 GDSC2 2.4438 5.2654 1.5477 14.0666
SU-DHL-1 GDSC2 2.4977 8.8985 -0.3776 21.778
MHH-CALL-4 GDSC2 2.5331 5.4243 1.3797 11.6926
OCI-AML-2 GDSC2 2.6314 3.6528 2.4578 7.8815
Hs 445 GDSC2 2.7621 10.3388 -0.6633 24.7166
OCI-AML-3 GDSC2 2.827 7.2696 0.9218 16.5125
A3/Kawakami GDSC2 2.9131 6.9037 1.1799 14.7051
NU-DUL-1 GDSC2 2.9587 5.708 1.6114 8.9079
Karpas-620 GDSC2 3.0134 8.1924 0.625 17.6043
MOLM-13 GDSC2 3.0364 5.374 2.0492 8.9274
Karpas-422 GDSC2 3.0537 9.8448 -0.1656 21.556
697 GDSC2 3.0603 6.5119 1.504 12.2614
NB4 GDSC2 3.0729 5.237 1.9417 6.4912
ROS-50 GDSC2 3.1137 6.9131 1.1373 11.4159
MC116 GDSC2 3.1277 4.289 2.4586 3.0744
LP-1 GDSC2 3.1297 5.1726 2.0198 5.8392
RL GDSC2 3.1386 4.5622 2.3312 3.8483
MY-M12 GDSC2 3.1548 5.9192 1.6673 7.9945
CTB-1 GDSC2 3.2021 5.8579 1.7358 7.433
KG-1 GDSC2 3.2252 4.8835 2.4591 5.7506
NALM-6 GDSC2 3.2254 5.8526 1.9753 8.8076
SU-DHL-4 GDSC2 3.2439 5.0775 2.1568 4.6701
GA-10 GDSC2 3.2585 6.0354 1.912 9.1076
PF-382 GDSC2 3.3054 7.1151 1.4116 12.0875
Karpas-299 GDSC2 3.3105 4.586 2.6804 4.0952
MOLM-16 GDSC2 3.3217 5.2598 2.1257 4.6674
SUP-M2 GDSC2 3.3494 6.4871 1.7622 9.7828
MOLT-16 GDSC2 3.3663 6.0674 1.986 8.3266
VL51 GDSC2 3.3751 11.7033 -0.8246 23.4851
SUP-B15 GDSC2 3.3955 7.6983 1.1948 13.1392
BL-41 GDSC2 3.3983 6.3399 1.8761 8.9274
OPM-2 GDSC2 3.4125 7.7337 1.191 13.1122
MOLT-13 GDSC2 3.4328 6.3357 1.9065 8.6383
ME1 GDSC2 3.4438 9.2393 0.4642 17.1708
Namalwa GDSC2 3.4463 6.1812 1.9946 8.0454
WIL2 NS GDSC2 3.4783 7.4546 1.3844 11.7526
DEL GDSC2 3.4788 8.2629 0.9809 14.1638
EoL-1 GDSC2 3.5254 7.8745 1.2129 12.657
KOPN-8 GDSC2 3.5549 6.3721 1.9864 7.7981
OCI-Ly19 GDSC2 3.565 5.807 2.0349 4.65
L-363 GDSC2 3.5672 6.3005 2.0317 7.4798
JJN-3 GDSC2 3.5971 6.5279 1.9421 7.9622
SU-DHL-5 GDSC2 3.6027 5.5667 2.4241 4.9188
KE-37 GDSC2 3.6253 7.5345 1.4628 10.8629
OCI-AML-5 GDSC2 3.6339 5.3335 2.5628 3.9722
Karpas-1106P GDSC2 3.6412 5.3079 2.5809 3.8413
H9 GDSC2 3.6811 14.0326 -1.7371 25.9936
DG-75 GDSC2 3.6996 6.9594 1.8076 8.5308
MHH-CALL-2 GDSC2 3.7094 7.319 1.6364 9.5671
BC-1 GDSC2 3.7165 8.8009 0.9039 13.9382
GR-ST GDSC2 3.724 8.7581 0.9312 13.76
SKM-1 GDSC2 3.745 9.5663 0.3152 14.4898
Jiyoye GDSC2 3.7795 7.1121 1.7933 8.4113
RPMI-6666 GDSC2 3.7968 7.251 1.7378 8.7106
EJM GDSC2 3.8043 7.4309 1.6543 9.2074
L-1236 GDSC2 3.8211 7.1107 1.8257 8.1036
TALL-1 [Human adult T-ALL] GDSC2 3.8309 8.5677 0.8746 11.0814
LAMA-84 GDSC2 3.8644 6.8046 2.0094 6.8546
SU-DHL-10 GDSC2 3.8764 6.7688 2.0359 6.6612
A4/Fukuda GDSC2 3.8986 14.358 -1.7232 25.3547
ARH-77 GDSC2 3.957 5.9486 2.4928 3.6653
EB2 GDSC2 3.9816 8.4908 1.2646 11.1135
Reh GDSC2 4.0281 9.5972 0.7516 13.9583
Raji GDSC2 4.0357 5.6837 2.6697 2.4573
P30/OHK GDSC2 4.0386 6.3705 2.3457 4.3813
MEG-01 GDSC2 4.0418 7.1421 1.9735 6.6514
KY821 GDSC2 4.0603 8.1131 1.5104 9.4377
HL-60 GDSC2 4.0652 6.07 2.507 3.3567
OCI-M1 GDSC2 4.0776 5.784 2.6492 2.4988
ALL-PO GDSC2 4.08 7.7766 1.6904 8.2949
MLMA GDSC2 4.0972 7.7431 1.7194 8.0765
KM-H2 GDSC2 4.1096 7.6917 1.7536 7.8382
NKM-1 GDSC2 4.1393 7.073 2.0762 5.8
ATN-1 GDSC2 4.1517 9.1398 1.0723 11.8105
BE-13 GDSC2 4.1542 11.5068 -0.0993 18.0525
RS4;11 GDSC2 4.1678 6.8341 2.211 4.92
PL-21 GDSC2 4.1785 11.4316 -0.2785 16.4596
SCC-3 GDSC2 4.2498 8.0544 1.6773 7.9731
TK [Human B-cell lymphoma] GDSC2 4.274 6.1286 2.6103 2.3752
KCL-22 GDSC2 4.2765 7.0568 2.1776 4.8923
CESS GDSC2 4.2786 7.2344 2.0941 5.3894
BALL-1 GDSC2 4.281 7.1895 2.1173 5.2447
CA46 GDSC2 4.3023 7.5467 1.9602 6.1447
WSU-NHL GDSC2 4.3115 6.2243 2.5889 2.4314
MOLP-8 GDSC2 4.3284 7.0216 2.2286 4.4832
RPMI-8866 GDSC2 4.3472 7.2171 2.1483 4.9224
Granta-519 GDSC2 4.3917 7.4757 2.0547 5.3886
K-562 GDSC2 4.4053 8.1967 1.7177 7.3774
SUP-HD1 GDSC2 4.4155 7.0145 2.288 3.9647
HAL-01 GDSC2 4.5056 7.1317 2.2899 3.7873
CTV-1 GDSC2 4.5081 9.015 1.3931 9.0749
RC-K8 GDSC2 4.5294 9.2372 1.3002 9.5712
MOLT-4 GDSC2 4.567 6.9187 2.4247 2.9201
Mono-Mac-6 GDSC2 4.5766 9.6578 1.1289 10.4536
KMS-12-BM GDSC2 4.5835 6.554 2.5967 1.9717
Daudi GDSC2 4.6581 6.4513 2.6805 1.4557
U266B1 GDSC2 4.7209 14.1019 -0.9512 20.3584
CML-T1 GDSC2 4.7535 8.4848 1.8138 6.0795
HDLM-2 GDSC2 4.7657 9.2131 1.4754 8.0279
U-698-M GDSC2 5.0775 7.6194 2.3997 2.3009
L-540 GDSC2 5.1004 7.4329 2.4911 1.8284
TUR GDSC2 5.141 6.8429 2.7489 0.709
KMOE-2 GDSC2 5.1501 7.3319 2.5578 1.4673
DB GDSC2 5.1642 7.1035 2.6571 1.0355
NOMO-1 GDSC2 5.1787 6.592 2.8584 0.3502
SU-DHL-8 GDSC2 5.2379 6.7217 2.8343 0.3859
MHH-PREB-1 GDSC2 5.3329 6.7067 2.8761 0.2467
LC4-1 GDSC2 5.3475 11.289 0.8738 10.1859
SK-MM-2 GDSC2 5.3534 7.2675 2.6768 0.8102
HEL GDSC2 5.3767 15.7147 -1.5019 18.9842
HC-1 GDSC2 5.4319 7.2192 2.7283 0.5882
L-428 GDSC2 5.4367 6.9631 2.8241 0.3244
YT GDSC2 5.4458 6.8555 2.8656 0.2308
Karpas-231 GDSC2 5.467 7.0467 2.8056 0.3562
MN-60 GDSC2 5.7399 7.5945 2.7131 0.4697
ALL-SIL GDSC2 5.8157 7.6253 2.7314 0.3908
DND-41 GDSC2 5.8323 8.0089 2.5968 0.7588
RPMI-8226 GDSC2 5.9389 7.674 2.7603 0.2831
⏷ Show the Full List of 164 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC2 3.4833 5.4694 2.3795 5.5136
FLO-1 GDSC2 3.7869 9.13 0.7957 14.3609
OACP4 C GDSC2 3.9333 7.5503 1.6932 8.639
ESO-26 GDSC2 4.0158 8.7934 1.1408 11.758
HCE-4 GDSC2 4.1192 12.6816 -0.9426 19.6809
KYSE-50 GDSC2 4.1763 8.9801 1.1694 11.1821
SK-GT-4 GDSC2 4.3006 7.8411 1.8169 7.0136
TE-12 GDSC2 4.3758 10.0731 0.5342 11.712
KYAE-1 GDSC2 4.7918 6.8637 2.574 1.8071
ESO-51 GDSC2 5.4731 7.5172 2.6321 0.8816
OACM5.1 C GDSC2 6.1088 8.402 2.563 0.7012
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 4.9479 11.8275 0.3363 13.9022
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-6 GDSC2 0.517 3.9115 -0.0038 27.6276
KP-N-YS GDSC2 0.6254 3.8652 0.1297 26.4387
SJNB-14 GDSC2 1.0989 4.1743 0.6194 24.8639
CHP-212 GDSC2 1.2549 2.7344 1.1951 21.0493
CHP-134 GDSC2 1.3047 3.3308 1.1181 21.225
IMR-5 GDSC2 1.3351 2.616 1.2977 20.1286
LA-N-6 GDSC2 2.2261 3.4072 2.0176 8.9133
Kelly GDSC2 2.2714 5.6387 1.2033 16.7713
SK-N-MC-IXC GDSC2 2.8374 9.9127 -0.5928 21.7206
MHH-NB-11 GDSC2 2.8978 6.2254 1.3013 11.0333
TGW GDSC2 2.9551 5.3353 1.9953 9.5287
SJNB-17 GDSC2 3.0854 5.0088 2.0658 5.6709
SJNB-12 GDSC2 3.4121 7.1729 1.471 11.4112
SK-N-SH GDSC2 3.5683 6.8369 1.7653 9.1466
SJNB-10 GDSC2 3.724 7.7108 1.4529 10.6555
SJNB-5 GDSC2 3.8316 6.1792 2.0386 4.0508
CHP-126 GDSC2 3.8412 5.6928 2.2734 2.6532
NB1 GDSC2 3.8745 11.1654 -0.1494 19.0531
NB69 GDSC2 3.922 10.6508 0.1447 17.4777
SK-N-DZ GDSC2 3.9592 6.0971 2.4229 4.0844
KP-N-RT-BM-1 GDSC2 4.1709 6.198 2.2392 2.293
GI-ME-N GDSC2 4.2401 8.4756 1.4645 9.2765
SK-N-BE(2)-M17 GDSC2 4.3625 8.8742 1.358 9.6194
SK-N-FI GDSC2 4.5311 9.1617 1.338 9.346
NH-12 GDSC2 4.7599 17.6595 -2.6866 26.1686
SJNB-7 GDSC2 5.1875 7.4419 2.5307 1.5485
GOTO GDSC2 5.2458 7.9394 2.3508 2.3257
SiMa GDSC2 5.3498 7.5867 2.5491 1.3066
SK-N-AS GDSC2 5.6146 7.0475 2.8603 0.1917
NB(TU)1 GDSC2 5.8707 7.7982 2.6902 0.469
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 4.1344 6.6031 2.2991 4.4591
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-148 GDSC2 0.9386 4.2481 0.4201 26.6434
MDA-MB-415 GDSC2 1.0018 5.7771 -0.1357 29.0911
AU565 GDSC2 1.0314 7.2858 -0.7873 31.6795
HCC1569 GDSC2 1.5807 7.1862 -0.3681 24.9617
MRK-nu-1 GDSC2 1.6152 7.1466 -0.149 26.5662
OCUB-M GDSC2 1.6561 10.5757 -1.7722 32.4876
YMB-1-E GDSC2 1.9301 4.0764 1.4298 13.5634
MDA-MB-175-VII GDSC2 2.3509 4.2079 1.936 12.079
CAMA-1 GDSC2 2.5497 3.2682 2.4932 8.0449
MDA-MB-453 GDSC2 2.5764 4.1234 2.2054 9.5855
COLO 824 GDSC2 2.6612 7.1491 0.8332 17.5755
UACC-893 GDSC2 2.6978 5.3325 1.5732 9.9484
HCC1187 GDSC2 2.7046 7.3111 0.7921 17.6654
HDQ-P1 GDSC2 2.7229 6.8296 1.0469 16.1213
Evsa-T GDSC2 2.9156 5.3262 1.9638 9.856
Hs 578T GDSC2 2.9926 20.6613 -5.6237 36.3251
HCC1954 GDSC2 3.0419 6.6247 1.4317 12.7645
BT-549 GDSC2 3.12 10.6226 -0.498 22.8697
UACC-812 GDSC2 3.2079 5.2762 2.2482 7.1367
MDA-MB-330 GDSC2 3.2803 6.0286 1.7125 7.3686
MDA-MB-468 GDSC2 3.3102 5.4599 2.2432 6.8637
HCC2218 GDSC2 3.315 5.8086 1.8488 6.4214
HCC2157 GDSC2 3.4007 6.5714 1.7624 9.6341
MCF-7 GDSC2 3.4126 7.2453 1.4352 11.6299
HCC1599 GDSC2 3.4759 5.9985 1.8765 5.8421
MDA-MB-231 GDSC2 3.5841 12.1864 -0.8938 23.1574
CAL-120 GDSC2 3.7513 6.4577 2.0959 6.5972
CAL-51 GDSC2 3.7803 9.2598 0.7258 14.7718
EFM-192A GDSC2 3.8774 9.5773 0.6443 14.9588
HCC1500 GDSC2 4.0478 8.8732 1.1256 11.7647
MDA-MB-361 GDSC2 4.0639 6.5635 2.2701 4.7856
ZR-75-30 GDSC2 4.1693 10.4553 0.4345 15.3132
HCC70 GDSC2 4.2647 9.3223 1.0666 11.5603
EFM-19 GDSC2 4.2936 8.2904 1.5935 8.3762
DU4475 GDSC2 4.465 10.5369 0.6171 13.5816
JIMT-1 GDSC2 4.4707 7.8033 1.9511 5.8425
HCC1806 GDSC2 4.4945 7.1532 2.273 3.9046
MDA-MB-436 GDSC2 4.5708 6.8466 2.4594 2.7227
HCC1395 GDSC2 4.6133 10.4308 0.7778 12.3438
BT-20 GDSC2 4.8449 6.5248 2.7415 0.9811
MFM-223 GDSC2 5.0463 9.575 1.4892 7.3725
BT-474 GDSC2 5.0671 6.5152 2.8422 0.4524
HCC1419 GDSC2 5.2352 7.5031 2.5286 1.5075
CAL-85-1 GDSC2 5.2835 7.2123 2.6677 0.8956
HCC1143 GDSC2 5.3611 11.4427 0.8095 10.5035
MDA-MB-157 GDSC2 5.3656 7.7112 2.5061 1.4729
HCC38 GDSC2 5.5468 7.3629 2.7214 0.5439
HCC1428 GDSC2 5.581 7.0793 2.837 0.2447
T-47D GDSC2 5.6059 8.6285 2.2435 2.4006
BT-483 GDSC2 5.62 7.3959 2.7385 0.4591
HCC1937 GDSC2 6.1437 8.044 2.7061 0.326
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-245MG GDSC2 0.5165 3.6347 0.0932 27.1306
H4 GDSC2 1.2621 4.51 0.6663 23.889
CAS-1 GDSC2 1.3155 5.9804 0.0945 26.6344
D-336MG GDSC2 1.3303 5.0114 0.4041 21.9186
SW1783 GDSC2 1.4783 4.3499 0.9589 21.3381
LN-18 GDSC2 1.5329 5.0168 0.7416 22.322
SW1088 GDSC2 1.5353 5.7589 0.4167 24.0751
D-423MG GDSC2 1.6285 4.981 0.7198 18.9374
D-566MG GDSC2 1.9036 4.6943 1.1266 15.4764
D283 Med GDSC2 1.9973 3.2821 1.887 13.8722
MOG-G-UVW GDSC2 2.0692 4.5864 1.4816 15.8878
T98G GDSC2 2.4362 7.2122 0.597 19.6807
GaMG GDSC2 2.5759 8.6424 0.017 22.2346
GI-1 GDSC2 2.5966 6.9262 0.8846 17.4977
8-MG-BA GDSC2 2.8092 4.737 2.1521 9.0457
SF126 GDSC2 2.9414 4.0447 2.4281 3.7951
D-263MG GDSC2 3.0612 6.7533 1.3844 12.995
MOG-G-CCM GDSC2 3.1158 7.1544 1.2314 13.7568
DK-MG GDSC2 3.2699 5.7337 2.0724 8.0621
M059J GDSC2 3.2777 6.4326 1.7296 10.1964
SF295 GDSC2 3.3865 5.5744 2.019 5.1739
YKG-1 GDSC2 3.4222 5.2236 2.2174 3.8543
SF268 GDSC2 3.5458 11.5661 -0.6151 22.1035
D-542MG GDSC2 3.5561 7.4543 1.2176 9.7208
KS-1 [Human Krukenberg tumour] GDSC2 3.5971 8.7822 0.8176 14.7673
D-502MG GDSC2 3.6247 7.7779 1.1096 10.2011
D-247MG GDSC2 3.6587 7.3838 1.3299 8.7744
SK-MG-1 GDSC2 3.6926 9.0082 0.7815 14.703
Hs 683 GDSC2 3.7326 7.2284 1.4609 7.7916
YH-13 GDSC2 3.8463 7.9778 1.4153 10.5594
KNS-81-FD GDSC2 3.8949 8.847 0.7846 11.4479
Onda 10 GDSC2 3.9285 8.843 0.8116 11.2075
SNB-75 GDSC2 3.9587 8.2851 1.1076 9.3887
Daoy GDSC2 4.0144 7.2137 1.9186 7.0534
LNZTA3WT4 GDSC2 4.0394 9.2397 0.9376 12.8755
PFSK-1 GDSC2 4.0693 6.5673 2.2719 4.7629
GB-1 GDSC2 4.071 8.0745 1.5374 9.2479
LN-229 GDSC2 4.1025 6.3746 2.3869 3.9982
AM-38 GDSC2 4.1748 7.3202 1.9812 6.2988
NMC-G1 GDSC2 4.2613 6.1861 2.2947 1.8694
ONS-76 GDSC2 4.3219 8.4244 1.5485 8.5808
SF539 GDSC2 4.6303 11.4809 0.2748 14.9757
D-392MG GDSC2 4.6725 9.5104 1.2682 9.433
U-118MG GDSC2 4.7205 10.208 0.9634 11.0606
A-172 GDSC2 4.7218 9.4587 1.3274 8.9813
KNS-42 GDSC2 4.8083 13.3018 -0.7326 17.0637
42-MG-BA GDSC2 4.8127 12.5663 -0.1244 16.4983
Onda 11 GDSC2 4.8373 8.8916 1.4082 5.7912
LN-405 GDSC2 4.9582 6.4126 2.8357 0.5383
U-251MG GDSC2 5.0714 6.9509 2.6754 1.0443
Becker GDSC2 5.0844 10.5019 1.0733 9.6428
DBTRG-05MG GDSC2 5.4474 10.9345 1.1077 8.7129
KALS-1 GDSC2 5.5994 16.3823 -1.4212 20.1174
U-87MG ATCC GDSC2 5.8923 7.1455 2.9235 0.0628
KINGS-1 GDSC2 5.9639 7.9845 2.6589 0.5074
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC2 3.6091 7.1112 1.6609 9.6853
TGBC1TKB GDSC2 4.0012 6.6628 2.1781 5.4876
ETK-1 GDSC2 6.1159 8.2817 2.6102 0.5646
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EN GDSC2 2.1063 5.4989 1.107 17.9571
RL95-2 GDSC2 2.7211 6.3291 1.2924 14.6556
MFE-319 GDSC2 2.893 4.3701 2.4082 7.1662
ESS-1 GDSC2 3.418 7.979 1.073 13.799
AN3-CA GDSC2 3.4612 6.2453 1.9746 8.13
MFE-280 GDSC2 4.3176 7.921 1.79 7.1378
MFE-296 GDSC2 4.4043 6.4186 2.5555 2.4636
KLE GDSC2 4.919 7.3597 2.4273 2.3749
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB996-RCC GDSC2 0.941 6.1669 -0.3695 30.3986
CAL-54 GDSC2 0.9604 3.861 0.5797 25.7039
BFTC-909 GDSC2 1.9174 5.1053 1.0975 18.7426
KTCTL-140 GDSC2 1.967 5.2697 0.9206 16.4728
786-O GDSC2 2.0114 6.2599 0.6562 20.8994
KTCTL-26A GDSC2 2.0603 4.2618 1.4809 12.7503
RXF 393L GDSC2 2.0708 4.7285 1.277 13.9428
UO-31 GDSC2 2.1547 5.529 0.9768 15.4589
SW156 GDSC2 2.8318 5.2375 1.7382 8.4906
KTCTL-13 GDSC2 2.8677 5.6839 1.5463 9.5899
SW13 GDSC2 3.0271 5.7533 1.8525 10.1925
KTCTL-1M GDSC2 3.0582 6.4038 1.3464 10.2808
NCC021 GDSC2 3.1081 4.8536 2.1617 5.0019
VMRC-RCW GDSC2 3.3654 6.1465 1.7199 7.0992
LB1047-RCC GDSC2 3.4455 5.8994 1.9028 5.7531
LB2241-RCC GDSC2 3.5176 6.6565 1.5832 7.5642
RCC10RGB GDSC2 3.6096 6.9553 1.7391 9.198
769-P GDSC2 3.6131 11.7941 -0.674 22.161
NCC010 GDSC2 3.752 6.4111 1.8732 5.2198
A-704 GDSC2 3.7836 10.643 0.0387 18.3929
HA7-RCC GDSC2 3.8289 6.4251 1.9193 4.7737
KTCTL-21 GDSC2 3.8579 8.6446 0.8568 11.1186
BB65-RCC GDSC2 3.872 6.7651 1.7853 5.4913
TK-10 GDSC2 4.0541 8.3923 1.368 10.3109
A-498 GDSC2 4.1258 9.1674 1.0391 12.0681
OS-RC-2 GDSC2 4.415 10.8865 0.4075 14.8244
Caki-1 GDSC2 4.5082 10.2345 0.5496 11.3219
ACHN GDSC2 4.7297 7.9667 2.0416 4.8043
KMRC-20 GDSC2 4.7853 10.9369 0.6544 12.6104
KMRC-1 GDSC2 4.8017 11.3615 0.4588 13.611
KTCTL-195 GDSC2 4.9088 9.197 1.5783 7.1361
VMRC-RCZ GDSC2 5.054 11.7643 0.4427 13.1098
SN12C GDSC2 5.7094 7.4085 2.7685 0.3462
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LoVo GDSC2 0.9337 4.8414 0.1865 27.8559
DiFi GDSC2 1.5521 5.9822 0.3321 24.4494
LS411N GDSC2 1.6338 5.7613 0.5149 23.1501
HT115 GDSC2 1.6878 6.2238 0.1966 21.6618
HCT 15 GDSC2 1.9222 6.9195 0.2556 23.3854
SW948 GDSC2 1.9308 5.7561 0.8138 20.3225
CL-11 GDSC2 2.5864 3.8119 2.3474 8.7082
SNU-407 GDSC2 2.6049 9.2077 -0.2379 23.3557
HCT 116 GDSC2 2.8366 3.8877 2.5757 6.3557
MDST8 GDSC2 3.1019 5.2538 2.167 7.9782
C2BBe1 GDSC2 3.2669 6.3679 1.7529 10.083
SW1417 GDSC2 3.4426 8.0991 1.0332 13.9625
KM12 GDSC2 3.49 7.7917 1.2255 12.6823
GP5d GDSC2 3.5371 6.797 1.7603 9.2639
HT-29 GDSC2 3.6088 7.4205 1.5065 10.3144
NCI-H508 GDSC2 3.6498 8.4232 0.8091 11.9295
NCI-H747 GDSC2 3.8049 8.5722 1.0877 12.6271
SNU-283 GDSC2 3.9314 6.1049 2.1381 3.2688
SK-CO-1 GDSC2 3.9476 7.491 1.7331 8.358
HT-55 GDSC2 3.9668 6.6377 2.1659 5.6416
RKO GDSC2 4.1268 6.622 2.2849 4.5609
SNU-175 GDSC2 4.1317 7.1193 2.0484 5.9861
CaR-1 GDSC2 4.2157 8.4408 1.4637 9.3397
SNU-81 GDSC2 4.2338 6.8404 1.9847 3.6017
HCC2998 GDSC2 4.4997 8.5589 1.6081 7.8225
SNU-C1 GDSC2 4.5902 7.7465 2.0562 4.9841
CW-2 GDSC2 4.5922 8.5642 1.669 7.2615
CCK-81 GDSC2 4.6488 6.7778 2.5343 2.2028
LS123 GDSC2 4.7215 10.5242 0.81 11.9114
T84 GDSC2 4.7762 9.165 1.5055 7.8307
LS180 GDSC2 4.809 10.9516 0.6642 12.5021
COLO205 GDSC2 4.8405 6.0883 2.909 0.3802
NCI-H716 GDSC2 4.8669 7.9404 2.1379 4.0141
SW1463 GDSC2 4.8757 7.1777 2.4831 2.1502
COLO 320HSR GDSC2 4.9426 6.9165 2.6281 1.374
SNU-C2B GDSC2 4.9782 9.9362 1.2725 8.746
LS513 GDSC2 5.0142 9.3777 1.5615 7.0229
SW620 GDSC2 5.1122 8.879 1.8558 5.0106
LS1034 GDSC2 5.2535 6.7546 2.8284 0.3942
SNU-C5 GDSC2 5.3662 8.4549 2.1923 2.9584
RCM-1 [Human ESC] GDSC2 5.5874 7.1886 2.8007 0.3195
SW1116 GDSC2 5.6719 7.186 2.833 0.2247
SW626 GDSC2 5.9159 7.8564 2.6867 0.4578
COLO 678 GDSC2 6.0092 7.9988 2.6713 0.4557
SW837 GDSC2 6.1177 7.8624 2.7599 0.2322
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 1.9554 3.8596 1.6556 15.3462
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep 3B2.1-7 GDSC2 1.4276 3.5607 1.1038 17.5369
JHH-4 GDSC2 2.3495 3.5366 2.1952 10.5877
JHH-2 GDSC2 2.4341 7.7045 0.3529 21.0088
JHH-7 GDSC2 2.8103 4.9202 2.0646 9.5843
SK-HEP-1 GDSC2 3.3322 7.9588 1.012 14.4108
SNU-387 GDSC2 3.4545 6.5976 1.7932 9.2882
Hep-G2/C3A GDSC2 3.4876 5.1327 2.5507 4.4222
HuH-1 GDSC2 3.55 8.0752 1.1325 13.0671
JHH-6 GDSC2 4.1843 8.4476 1.4374 9.5731
Huh-7 GDSC2 4.254 8.3278 1.5469 8.7494
SNU-423 GDSC2 4.5064 9.1149 1.3434 9.371
SNU-398 GDSC2 4.8181 8.2275 1.9756 5.02
HLE GDSC2 4.9885 7.2576 2.5081 1.8819
JHH-1 GDSC2 5.1345 6.6127 2.8333 0.4415
SNU-449 GDSC2 5.3251 16.6567 -1.7585 21.9431
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 182 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COR-L311 GDSC2 -0.0952 2.6019 -0.2382 34.9704
NCI-H847 GDSC2 -0.0369 6.7285 -1.6193 39.2362
A-427 GDSC2 1.4888 5.8738 0.1684 22.5786
NCI-H2172 GDSC2 1.4996 5.0629 0.5528 20.4035
Lu-135 GDSC2 1.5704 4.2216 1.1068 20.1114
NCI-H2171 GDSC2 1.6186 3.2886 1.4048 15.01
Lu-134-A GDSC2 1.6649 3.1439 1.5013 14.2684
NCI-H1975 GDSC2 1.8107 7.3098 -0.0384 25.2767
IST-SL1 GDSC2 1.9237 3.6657 1.5946 12.6221
DMS 53 GDSC2 1.9564 6.9162 0.29 23.0771
NCI-H1781 GDSC2 1.9828 5.5695 0.9518 19.3323
LXF 289 GDSC2 1.9955 4.4466 1.4649 16.2821
NCI-H720 GDSC2 2.0496 5.1961 1.19 17.6854
NCI-H647 GDSC2 2.1365 4.993 1.2164 14.0705
IST-SL2 GDSC2 2.2039 10.9506 -1.6568 28.0787
NCI-H292 GDSC2 2.2252 6.0441 0.7922 16.3193
EKVX GDSC2 2.2351 6.1851 0.7324 16.6396
NCI-H1436 GDSC2 2.2762 4.4751 1.5975 11.2343
NCI-H1876 GDSC2 2.2886 4.591 1.7045 13.7014
A-549 GDSC2 2.2982 6.4979 0.8169 18.9338
NCI-H2170 GDSC2 2.3905 6.1072 1.0932 16.9933
NCI-H838 GDSC2 2.5129 5.3199 1.4127 11.5544
BEN GDSC2 2.5174 6.9524 0.6084 16.4225
NCI-H69 GDSC2 2.5255 9.8727 -0.6388 25.397
HCC33 GDSC2 2.5478 7.5963 0.3149 17.9988
NCI-H82 GDSC2 2.5505 5.0112 1.7718 12.3115
NCI-H1944 GDSC2 2.556 8.3904 0.1242 21.7682
SBC-1 GDSC2 2.6015 5.8341 1.2386 12.3456
DMS 273 GDSC2 2.7252 5.7877 1.5622 12.9899
RERF-LC-MS GDSC2 2.8025 4.8555 1.903 7.5419
NCI-H810 GDSC2 2.8286 6.4118 1.3488 13.9561
SBC-3 GDSC2 2.9498 6.6574 1.3347 13.65
NCI-H211 GDSC2 3.0001 8.7632 0.3286 19.251
COR-L321 GDSC2 3.0398 4.6964 2.1848 5.0471
NCI-H2227 GDSC2 3.0511 6.45 1.3174 10.4818
NCI-H1355 GDSC2 3.1028 6.3005 1.6463 11.2462
NCI-H2066 GDSC2 3.1602 6.6892 1.5017 11.9678
NCI-H2009 GDSC2 3.161 6.8113 1.4414 12.337
NCI-H250 GDSC2 3.1749 6.0032 1.6416 8.1005
HCC44 GDSC2 3.1795 7.699 1.0136 14.8609
LB647-SCLC GDSC2 3.2112 5.3473 1.9974 5.7595
NCI-H146 GDSC2 3.221 5.2825 2.0372 5.4826
HCC366 GDSC2 3.2607 5.8292 1.7963 6.8943
NCI-H748 GDSC2 3.27 6.7351 1.3524 9.6487
NCI-H2196 GDSC2 3.3053 5.406 2.041 5.2399
NCI-H1155 GDSC2 3.3133 5.9009 2.0252 8.2327
NCI-H2804 GDSC2 3.3272 7.0201 1.2557 10.092
HCC827 GDSC2 3.3441 4.8726 2.565 4.7285
NCI-H1836 GDSC2 3.3589 5.2084 2.1787 4.245
NCI-H1770 GDSC2 3.3693 6.0486 1.7715 6.7661
NCI-H460 GDSC2 3.3775 6.2215 1.692 7.2427
NCI-H2810 GDSC2 3.3995 7.1093 1.268 9.8217
NCI-H2030 GDSC2 3.4119 7.9296 0.8695 12.2064
COR-L303 GDSC2 3.4278 5.4054 2.1325 4.3665
NCI-H2122 GDSC2 3.4657 4.8861 2.6562 3.8154
NCI-H1993 GDSC2 3.468 10.7009 -0.2466 20.6759
NCI-H345 GDSC2 3.4686 4.7584 2.474 2.1889
NCI-H2110 GDSC2 3.496 7.7665 1.0165 11.0992
COR-L279 GDSC2 3.539 8.2469 1.0379 13.6573
NCI-H2081 GDSC2 3.5506 13.6792 -1.888 24.8845
NCI-H2803 GDSC2 3.5658 6.3142 1.7875 6.1772
NCI-H1734 GDSC2 3.5709 5.5664 2.1558 3.8957
EMC-BAC-1 GDSC2 3.6061 6.3661 1.7915 6.0568
NCI-H446 GDSC2 3.671 6.3359 2.095 6.8081
NCI-H1105 GDSC2 3.6972 8.0926 1.0088 10.6224
CAL-12T GDSC2 3.7334 9.0184 0.578 13.0494
NCI-H2029 GDSC2 3.7757 6.1722 2.0045 4.3719
NCI-H524 GDSC2 3.7868 5.6722 2.5081 3.9478
NCI-H1693 GDSC2 3.8145 8.102 1.329 11.1651
COR-L32 GDSC2 3.8455 6.491 1.8989 4.861
UMC-11 GDSC2 3.8581 7.7547 1.535 9.7999
DMS 114 GDSC2 3.8808 5.9232 2.4525 4.0763
NCI-H1755 GDSC2 3.9162 9.265 0.8299 13.8157
COR-L23 GDSC2 3.9188 9.8061 0.5628 15.2922
NCI-H3255 GDSC2 3.961 6.314 2.0591 3.6738
NCI-H209 GDSC2 3.9638 7.2302 1.8735 7.4531
EMC-BAC-2 GDSC2 3.9643 9.8034 0.5998 14.9678
SK-MES-1 GDSC2 3.9769 10.5785 0.224 16.9245
NCI-H1793 GDSC2 3.9835 11.2014 -0.0809 18.4241
NCI-H1299 GDSC2 3.9853 20.4062 -4.6739 32.5245
NCI-H1437 GDSC2 4.0193 8.09 1.2463 8.4176
NCI-H1435 GDSC2 4.1007 7.914 1.6382 8.5632
NCI-H2135 GDSC2 4.1084 10.8136 -0.0259 15.365
NCI-H522 GDSC2 4.1125 9.7112 0.7599 13.691
NCI-H2444 GDSC2 4.1252 6.5482 2.0529 3.4062
NCI-H2731 GDSC2 4.162 8.247 1.5196 9.1334
NCI-H290 GDSC2 4.1741 6.2291 2.2271 2.3534
ABC-1 GDSC2 4.2098 8.2587 1.2978 7.6833
NCI-H510A GDSC2 4.2263 6.143 2.2945 1.9192
HOP-92 GDSC2 4.2465 9.044 1.1901 10.8869
NCI-H2373 GDSC2 4.2641 8.2258 1.604 8.3821
LC-2/ad GDSC2 4.2711 6.8801 1.9891 3.5119
NCI-H1092 GDSC2 4.2714 6.8391 2.2777 4.3061
NCI-H650 GDSC2 4.3164 6.3102 2.5528 2.6255
SHP-77 GDSC2 4.3238 10.4793 0.5401 14.3513
NCI-H526 GDSC2 4.3432 7.208 2.1499 4.9207
ChaGo-K-1 GDSC2 4.3497 9.9163 0.592 11.4511
NCI-H2795 GDSC2 4.3518 7.7624 1.8903 6.4585
COR-L95 GDSC2 4.3536 7.1674 2.176 4.7447
COR-L88 GDSC2 4.359 6.5642 2.4619 3.0658
PC-14 GDSC2 4.3814 8.9045 1.3568 9.296
NCI-H1703 GDSC2 4.4059 12.4562 -0.3763 18.6874
Lu-65 GDSC2 4.4406 16.1238 -2.1723 25.4123
LC-1/sq GDSC2 4.5314 7.9664 1.9138 5.9388
NCI-H1563 GDSC2 4.5339 7.5599 2.1078 4.791
HARA [Human squamous cell lung carcinoma] GDSC2 4.5524 9.1207 1.3729 9.0934
RERF-LC-KJ GDSC2 4.6026 12.5731 -0.2845 17.7667
NCI-H2869 GDSC2 4.6188 9.0392 1.1995 7.3996
NCI-H64 GDSC2 4.6499 12.2679 -0.0983 16.7731
NCI-H596 GDSC2 4.6511 14.4231 -1.1636 21.3731
NCI-H520 GDSC2 4.7 8.3608 1.8376 6.0469
EPLC-272H GDSC2 4.7063 7.8865 2.0643 4.7169
LCLC-103H GDSC2 4.8139 8.5452 1.8243 5.9004
SBC-5 GDSC2 4.817 5.7498 3.0214 0.1241
NCI-H1623 GDSC2 4.8351 12.3353 0.0057 15.819
NCI-H2141 GDSC2 4.8721 6.5678 2.7369 0.975
Ms-1 GDSC2 4.8833 6.3576 2.8249 0.6269
NCI-H2818 GDSC2 4.9085 10.9163 0.7519 11.799
HCC15 GDSC2 4.9241 8.0904 2.1036 4.108
NCI-H2405 GDSC2 4.9255 14.9844 -1.2328 20.9672
NCI-H2342 GDSC2 4.9693 11.0284 0.7403 11.7246
NCI-H1666 GDSC2 4.9798 7.9826 2.1853 3.5667
DMS 79 GDSC2 5.0132 8.3125 1.7745 3.4973
SW1271 GDSC2 5.0159 9.4823 1.5132 7.2957
NCI-H1915 GDSC2 5.0326 8.855 1.8178 5.5262
NCI-H2085 GDSC2 5.0855 7.391 2.5012 1.7982
NCI-H1792 GDSC2 5.1377 7.2779 2.5741 1.4087
EBC-1 GDSC2 5.1496 8.456 2.0706 3.9194
Lu-139 GDSC2 5.1665 10.406 1.1741 8.9101
CPC-N GDSC2 5.1666 7.2394 2.6035 1.253
IA-LM GDSC2 5.2134 7.021 2.7114 0.7895
NCI-H1573 GDSC2 5.2136 6.8238 2.7867 0.5365
NCI-H513 GDSC2 5.2311 7.8279 2.3907 2.1499
Calu-6 GDSC2 5.232 7.167 2.6626 0.9564
NCI-H196 GDSC2 5.2349 8.9426 1.9005 4.7102
NCI-H2369 GDSC2 5.2473 6.6437 2.8662 0.3011
NCI-H2722 GDSC2 5.2868 7.0599 2.728 0.6801
NCI-H1581 GDSC2 5.3135 10.9964 0.9905 9.6222
NCI-H2461 GDSC2 5.3476 8.6347 2.1033 3.4433
KNS-62 GDSC2 5.3597 6.9488 2.7993 0.4212
LCLC-97TM1 GDSC2 5.3787 11.72 0.6886 11.1099
NCI-H1838 GDSC2 5.3813 19.7684 -3.2544 26.3036
HOP-62 GDSC2 5.408 15.4704 -1.1136 19.3756
HCC78 GDSC2 5.422 7.4171 2.6487 0.8599
NCI-H1341 GDSC2 5.4341 7.1869 2.7412 0.5476
LK-2 GDSC2 5.4363 6.9325 2.8349 0.2995
Lu-99A GDSC2 5.4445 9.0415 1.9774 3.961
NCI-H226 GDSC2 5.5097 6.8697 2.8839 0.1786
NCI-H841 GDSC2 5.5122 8.3307 2.3215 2.1438
NCI-H2291 GDSC2 5.5191 7.3546 2.4007 0.4012
NCI-H2595 GDSC2 5.5349 8.0465 2.45 1.5458
Lu-165 GDSC2 5.5824 7.3076 2.7559 0.4308
NCI-H1688 GDSC2 5.6104 7.6887 2.6251 0.809
NCI-H322M GDSC2 5.6128 10.944 1.2089 7.8454
NCI-H2591 GDSC2 5.6608 10.6866 1.3582 6.9472
NCI-H1869 GDSC2 5.6771 8.106 2.492 1.2447
COR-L105 GDSC2 5.7016 12.0608 0.7409 10.1744
NCI-H1048 GDSC2 5.7475 7.3469 2.8045 0.2563
COLO 668 GDSC2 5.7728 7.9447 2.5962 0.7981
SK-LU-1 GDSC2 5.7822 7.5901 2.7312 0.4051
LOU-NH91 GDSC2 5.8034 19.7931 -2.9482 24.5815
NCI-H1568 GDSC2 5.8038 8.1761 2.5207 1.0364
NCI-H3122 GDSC2 5.8347 8.1878 2.5295 0.9824
NCI-H727 GDSC2 5.8415 7.8832 2.6475 0.5999
Calu-3 GDSC2 5.8656 7.5321 2.7831 0.2615
VMRC-LCD GDSC2 5.8812 14.2786 -0.1981 14.4328
NCI-H2228 GDSC2 5.934 7.8416 2.699 0.4197
NCI-H441 GDSC2 5.9993 7.7329 2.7619 0.2617
NCI-H661 GDSC2 6.0059 8.0411 2.6547 0.499
NCI-H358 GDSC2 6.025 8.4796 2.4989 0.9553
NCI-H2023 GDSC2 6.0484 16.2704 -1.0449 17.701
RERF-LC-Sq1 GDSC2 6.0747 8.5421 2.4962 0.9313
NCI-H1650 GDSC2 6.0751 8.0977 2.661 0.4528
NCI-H2087 GDSC2 6.097 8.1977 2.6333 0.5126
NCI-H2347 GDSC2 6.1448 8.671 2.4767 0.9499
NCI-H1651 GDSC2 6.25 7.9151 2.7887 0.158
NCI-H740 GDSC2 6.2673 8.5088 2.2724 0.4079
NCI-H1648 GDSC2 6.2729 8.2696 2.6745 0.3478
NCI-H23 GDSC2 6.3258 7.9548 2.8016 0.1283
PaCa-3 GDSC2 6.3642 8.7735 2.5282 0.6657
SW1573 GDSC2 6.3909 8.8173 2.5227 0.6675
NCI-H835 GDSC2 6.5342 8.4815 2.6959 0.234
⏷ Show the Full List of 182 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 4.0148 7.6078 1.7255 8.2388
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-11 GDSC2 1.8649 5.6558 0.6383 18.5137
TE-10 GDSC2 2.8456 5.5014 1.6185 9.2028
EC-GI-10 GDSC2 3.3589 5.1184 2.4543 5.3864
TE-6 GDSC2 3.3782 5.9693 2.0449 7.9211
T.T GDSC2 3.7422 6.7057 1.9662 7.4305
TE-9 GDSC2 3.7817 5.2209 2.7229 2.6457
KYSE-450 GDSC2 4.0695 6.0487 2.5199 3.2717
TE-15 GDSC2 4.086 11.0465 0.0765 17.3745
KYSE-510 GDSC2 4.2517 6.5734 2.1172 2.8297
OE21 GDSC2 4.2558 6.2975 2.5216 2.9089
COLO 680N GDSC2 4.3944 6.4706 2.5261 2.643
OE33 GDSC2 4.4112 6.7028 2.43 3.1554
OE19 GDSC2 4.684 7.1301 2.3974 2.881
KYSE-140 GDSC2 4.7746 8.9496 1.6073 7.2414
TE-1 GDSC2 4.8789 8.1727 2.0386 4.5513
KYSE-520 GDSC2 4.9001 8.1033 2.0833 4.2627
KYSE-180 GDSC2 4.9617 11.5129 0.4995 13.0244
TE-5 GDSC2 5.0125 7.3414 2.4848 1.9648
KYSE-410 GDSC2 5.7221 9.6407 1.8675 4.1235
KYSE-150 GDSC2 5.8279 12.509 0.6114 10.5961
KYSE-270 GDSC2 5.9607 9.0007 2.2638 1.9209
TE-4 GDSC2 6.0087 7.6354 2.799 0.1946
KYSE-70 GDSC2 6.1151 7.7561 2.7954 0.176
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TOV-21G GDSC2 1.3874 4.9777 0.607 23.6719
DOV13 GDSC2 1.5491 3.6631 1.2843 19.2086
IGROV-1 GDSC2 1.6658 5.8798 0.4929 23.1397
JHOS-4 GDSC2 1.9243 3.7196 1.5736 12.7418
FU-OV-1 GDSC2 3.0088 4.8341 2.2913 7.4969
OVK18 GDSC2 3.1962 6.8028 1.2596 10.4285
EFO-27 GDSC2 3.3424 7.2259 1.1652 10.6073
TYK-nu GDSC2 3.3761 5.4711 2.2921 6.3643
JHOS-2 GDSC2 3.5984 5.5606 2.1776 3.7031
Caov-3 GDSC2 3.6979 7.6517 1.2271 9.3041
ES-2 GDSC2 3.7563 8.904 0.8841 13.9416
OVTOKO GDSC2 3.9465 10.2349 0.3712 16.2429
TOV-112D GDSC2 4.1118 6.1235 2.5121 3.2344
OV56 GDSC2 4.1651 8.1126 1.5878 8.7138
OVCAR-3 GDSC2 4.1881 8.6253 1.3529 10.0688
OC 314 GDSC2 4.2193 8.5331 1.4211 9.5857
OVISE GDSC2 4.4817 6.772 2.4408 2.9726
RMG-I GDSC2 4.4873 7.5692 2.0732 5.0854
SK-OV-3 GDSC2 4.7707 9.3251 1.425 8.3094
Caov-4 GDSC2 4.889 7.3018 2.4363 2.3702
Kuramochi GDSC2 5.0698 9.8751 1.3624 8.0467
OVCAR-8 GDSC2 5.076 15.4779 -1.3634 21.102
OV-90 GDSC2 5.1361 10.3739 1.1691 9.0001
OAW28 GDSC2 5.1779 7.8474 2.3546 2.3941
OAW42 GDSC2 5.2245 6.3566 2.9584 0.1272
EFO-21 GDSC2 5.2658 7.1888 2.6691 0.9046
OVKATE GDSC2 5.3195 6.6788 2.881 0.2411
OVCAR-4 GDSC2 5.7168 7.872 2.6002 0.8214
OVCAR-5 GDSC2 5.9519 8.6138 2.415 1.3129
A2780 GDSC2 5.9697 8.4898 2.4713 1.0906
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaTu 8988t GDSC2 2.7773 4.8407 2.0718 9.6547
QGP-1 GDSC2 3.8682 6.8835 1.7255 5.8622
DAN-G GDSC2 4.0606 5.8203 2.6216 2.6902
HPAC GDSC2 4.2904 7.0595 2.1856 4.8161
MIA PaCa-2 GDSC2 4.3592 7.6118 1.9677 5.9774
PaTu 8902 GDSC2 4.4591 6.4146 2.5889 2.1954
YAPC GDSC2 4.5778 6.3712 2.673 1.5928
KP-4 GDSC2 4.8317 6.4495 2.7657 0.8944
AsPC-1 GDSC2 4.8675 8.4006 1.926 5.2131
KP-2 GDSC2 5.084 10.778 0.9406 10.3787
BxPC-3 GDSC2 5.1093 12.3211 0.211 14.1632
Panc 04.03 GDSC2 5.1168 6.8669 2.7291 0.7983
SU.86.86 GDSC2 5.178 6.7613 2.7956 0.5302
CFPAC-1 GDSC2 5.3064 6.7048 2.8668 0.2765
Capan-1 GDSC2 5.3403 6.9295 2.7987 0.4324
Hs 766T GDSC2 5.3986 14.3186 -0.5565 17.091
PL4 GDSC2 5.4659 7.9803 2.4441 1.6403
Panc 10.05 GDSC2 5.4801 7.6857 2.5693 1.11
KP-3 GDSC2 5.6041 8.1562 2.4381 1.5288
MZ-PC-1 GDSC2 5.6191 7.9227 2.231 0.8314
SUIT-2 GDSC2 5.6806 7.3837 2.7664 0.3625
HuP-T4 GDSC2 5.6922 7.8207 2.6094 0.807
PSN1 GDSC2 5.7059 12.4907 0.5397 11.2076
KP-1N GDSC2 5.7561 7.909 2.6027 0.7875
Panc 08.13 GDSC2 5.8618 8.051 2.5931 0.7522
Panc 02.03 GDSC2 5.9107 7.4546 2.8261 0.175
Panc 03.27 GDSC2 5.9642 7.6336 2.7836 0.2319
HuP-T3 GDSC2 6.0766 8.0435 2.6811 0.4047
Capan-2 GDSC2 6.101 8.8489 2.3891 1.2909
SW1990 GDSC2 6.3077 8.336 2.6641 0.3578
HPAF-II GDSC2 6.3153 8.1421 2.7344 0.2249
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC2 3.6949 8.2837 1.1446 12.5909
NCI-H2452 GDSC2 4.596 14.3471 -1.1682 21.5286
NCI-H2052 GDSC2 5.0235 12.1548 0.2308 14.2614
IST-Mes1 GDSC2 5.1452 12.6022 0.0995 14.6328
MSTO-211H GDSC2 5.2605 7.4004 2.5825 1.2517
NCI-H28 GDSC2 5.3149 7.84 2.4281 1.8747
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC2 0.7137 6.5011 -0.7497 32.9528
22Rv1 GDSC2 3.0984 7.3722 1.1076 14.5537
NCI-H660 GDSC2 4.0853 5.6999 2.4112 1.5169
VCaP GDSC2 4.6186 8.1771 1.8713 6.0127
PC-3 GDSC2 5.561 8.9429 2.0851 3.2354
DU145 GDSC2 6.1868 13.8434 0.2143 11.8693
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 5.0111 7.1093 2.5819 1.5088
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-7951 GDSC2 1.1735 5.1125 0.3272 26.0739
Hs 940.T GDSC2 1.3066 5.8097 0.0179 24.0996
MZ-MEL-2 GDSC2 1.8971 3.2816 1.7092 12.0807
WM793 GDSC2 2.3032 5.1985 1.4414 15.2268
SK-MEL-3 GDSC2 2.3143 7.3778 0.2163 19.3163
G-mel GDSC2 2.34 3.6173 2.0515 8.2481
VMRC-MELG GDSC2 2.4265 4.5745 1.6955 10.0928
IST-MEL1 GDSC2 2.4314 8.9008 -0.2404 23.9598
CP50-MEL-B GDSC2 2.4507 3.4457 2.2394 6.6955
CP66-MEL GDSC2 2.9365 5.7113 1.5911 9.1019
A-431 GDSC2 3.1938 4.5835 2.3634 3.5013
MMAc-SF GDSC2 3.3355 5.2211 2.1551 4.4496
Hs 938.T GDSC2 3.3386 5.3628 2.0876 4.864
LB2518-MEL GDSC2 3.4406 5.1194 2.2813 3.4182
LOX-IMVI GDSC2 3.5643 8.2363 1.0637 13.4341
DJM-1 GDSC2 3.6241 6.2666 1.8531 5.6338
SH-4 GDSC2 3.6359 8.7258 0.877 14.3176
SK-MEL-30 GDSC2 3.7522 5.7142 2.2069 3.2092
SK-MEL-31 GDSC2 3.7871 8.4463 0.9017 11.0318
COLO 800 GDSC2 3.8279 6.1468 2.0515 3.9814
A101D GDSC2 3.8822 7.6712 1.5947 9.3725
IPC-298 GDSC2 3.8908 6.9037 1.7314 5.7767
SK-MEL-5 GDSC2 3.9978 7.1341 1.6938 5.773
RVH-421 GDSC2 4.1496 6.3006 2.1808 2.6454
IGR-37 GDSC2 4.1696 7.7625 1.7624 7.6438
451Lu GDSC2 4.2128 6.4251 2.1614 2.6494
COLO 783 GDSC2 4.2278 7.1348 1.8443 4.4199
WM278 GDSC2 4.2288 8.453 1.4673 9.2869
WM1552C GDSC2 4.3419 7.6805 1.9229 6.2838
HT-144 GDSC2 4.384 6.9305 2.3073 3.9123
A2058 GDSC2 4.3971 6.8013 2.3758 3.4909
MZ-MEL-7 GDSC2 4.3985 8.0239 1.5361 5.8871
SK-MEL-24 GDSC2 4.4333 10.4723 0.6254 13.6151
COLO 792 GDSC2 4.4377 7.6264 2.0135 5.5398
COLO 679 GDSC2 4.5489 9.5974 1.1387 10.4618
A-375 GDSC2 4.5944 6.8042 2.4921 2.43
Mel Ho GDSC2 4.6466 7.0497 2.1268 2.1993
WT2-iPS GDSC2 4.6798 7.2844 2.3253 3.182
LB373-MEL-D GDSC2 4.6934 6.2253 2.4867 0.591
GAK GDSC2 4.7379 6.1122 2.8567 0.6208
SK-MEL-2 GDSC2 4.8439 5.7415 3.0339 0.0976
IGR-1 GDSC2 4.8777 10.9193 0.7288 11.9947
SK-MEL-1 GDSC2 5.0291 6.4362 2.8561 0.4321
UACC-257 GDSC2 5.0326 7.0067 2.6346 1.252
WM35 GDSC2 5.3284 7.6996 2.4929 1.5679
A-388 GDSC2 5.4248 7.6469 2.254 0.8833
HMV-II GDSC2 5.4779 7.4223 2.6706 0.7449
M14 GDSC2 5.5618 7.0121 2.8534 0.2189
Mel JuSo GDSC2 5.5809 9.5351 1.8348 4.5082
WM115 GDSC2 5.6122 12.273 0.5811 11.1858
MeWo GDSC2 5.6252 7.3245 2.7664 0.3852
COLO 829 GDSC2 5.7565 7.5997 2.7177 0.45
G-361 GDSC2 5.9332 7.7325 2.7376 0.332
CHL-1 GDSC2 6.1785 17.5235 -1.562 19.3855
SK-MEL-28 GDSC2 6.3036 19.6882 -2.7768 21.4582
UACC-62 GDSC2 6.9318 18.3046 -1.4164 17.3458
EquiPSC Line K2 GDSC2 3.726 7.0942 1.5219 7.4329
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 1.4524 4.4051 0.794 19.2088
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 633.T GDSC2 0.3913 2.3864 0.322 29.7599
GCT GDSC2 0.9287 5.0805 0.0841 28.3824
STS-0421 GDSC2 2.6713 8.1221 0.1601 18.4528
TE 441.T GDSC2 3.044 4.3424 2.3651 3.894
Rh30 GDSC2 3.12 5.8736 1.8742 9.7658
SW982 GDSC2 3.2151 9.341 0.2229 19.131
Rh41 GDSC2 3.3426 6.5481 1.7261 10.0284
MES-SA GDSC2 3.9754 7.9276 1.5385 9.4793
VA-ES-BJ GDSC2 4.066 6.4245 2.3384 4.3671
EW-8 GDSC2 4.0757 6.7673 2.1798 5.3099
HT-1080 GDSC2 4.2332 8.7164 1.3413 10.0277
G-401 GDSC2 4.4992 7.515 2.1066 4.8653
MFH-ino GDSC2 4.6261 8.9093 1.5263 8.0297
SW684 GDSC2 4.7006 6.9637 2.4811 2.4071
A-204 GDSC2 4.7702 12.9438 -0.3418 17.6145
G-402 GDSC2 4.8554 10.7029 0.8182 11.5579
SW872 GDSC2 4.8776 11.3309 0.5283 13.0677
RD GDSC2 5.0652 10.4768 1.0723 9.6891
SK-UT-1 GDSC2 5.2602 8.3123 2.1969 3.0825
KYM-1 GDSC2 5.4801 6.8739 2.8718 0.2085
SK-LMS-1 GDSC2 5.7107 9.264 2.0262 3.3291
RKN GDSC2 5.7511 7.326 2.8131 0.2387
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-N87 GDSC2 0.9337 5.7201 -0.1811 29.603
AGS GDSC2 1.7661 5.692 0.6792 21.7218
SK-GT-2 GDSC2 1.7843 6.6539 0.2488 23.9523
23132/87 GDSC2 2.0528 6.1767 0.7359 20.2972
HGC-27 GDSC2 2.1115 7.7114 0.0517 23.7044
HSC-39 GDSC2 2.2524 3.2472 2.1742 11.1424
ECC12 GDSC2 3.3606 5.7625 1.9066 5.942
SCH GDSC2 3.3704 7.3271 1.1369 10.7044
NUGC-3 GDSC2 3.4633 5.7119 2.2426 6.433
MKN1 GDSC2 3.8486 10.1606 0.331 16.7225
MKN7 GDSC2 3.9399 6.5306 1.9431 4.4004
RF-48 GDSC2 4.1696 6.2904 2.4707 3.3659
SNU-1 GDSC2 4.3361 6.6419 2.4118 3.3947
SNU-5 GDSC2 4.3963 18.3221 -3.3027 28.6547
TMK-1 GDSC2 4.4545 9.9956 0.6278 11.0097
MKN28 GDSC2 4.4997 8.8276 1.4782 8.5928
Hs 746.T GDSC2 4.5574 6.1463 2.758 1.2082
MKN45 GDSC2 4.7054 14.8929 -1.3549 21.9652
KATO III GDSC2 4.7188 11.7827 0.1917 15.1809
RERF-GC-1B GDSC2 4.9163 7.9411 2.1669 3.7702
TGBC11TKB GDSC2 4.9977 6.9224 2.6523 1.2105
Fu97 GDSC2 5.0759 8.2822 2.1061 3.8442
OCUM-1 GDSC2 5.135 7.0588 2.6615 1.0435
IM95 GDSC2 5.3832 7.0991 2.7532 0.5406
ECC10 GDSC2 5.6628 7.5192 2.7102 0.515
NUGC-4 GDSC2 5.7296 7.7195 2.663 0.6153
GCIY GDSC2 5.8455 7.5196 2.78 0.2737
SNG-M GDSC2 2.8714 5.6977 1.7405 11.3969
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC2 2.0899 4.5145 1.3953 13.1547
K5 GDSC2 2.2008 3.7423 1.9625 12.5475
BHT-101 GDSC2 2.8361 4.2152 2.4259 7.264
8305C GDSC2 3.3321 4.7352 2.6238 4.3907
B-CPAP GDSC2 3.3759 5.6389 2.2081 6.8959
ML-1 [Human leukemia] GDSC2 3.4674 6.2412 1.7505 6.6488
ASH-3 GDSC2 3.6115 8.963 0.739 15.1712
CAL-62 GDSC2 3.7427 7.3244 1.6596 9.3355
IHH-4 GDSC2 4.2737 6.937 2.2328 4.5682
TT2609-C02 GDSC2 4.3534 8.143 1.7075 7.5547
HTC-C3 GDSC2 4.7543 6.8183 2.5738 1.8562
TT GDSC2 4.9394 6.3902 2.8363 0.5486
CGTH-W-1 GDSC2 5.3552 6.8964 2.8167 0.3775
8505C GDSC2 5.5364 7.0883 2.8171 0.3018
WRO GDSC2 5.6243 7.5656 2.6775 0.6316
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BB49-HNC GDSC2 0.5334 4.8087 -0.2256 31.678
HSC-3 GDSC2 0.9946 4.9178 0.22 27.4127
Detroit 562 GDSC2 1.1447 4.1797 0.6667 24.404
JHU-011 GDSC2 1.4143 4.528 0.7019 19.893
HO-1-u-1 GDSC2 1.4667 8.2393 -0.8136 29.9779
JHU-029 GDSC2 2.2402 16.2413 -4.264 34.709
KON GDSC2 2.5052 4.8916 1.6157 10.3163
BB30-HNC GDSC2 2.8302 5.0446 1.833 7.8971
BICR 31 GDSC2 3.1025 4.6263 2.2707 4.3282
BICR 10 GDSC2 3.1127 7.7582 0.9271 15.5728
PCI-15A GDSC2 3.2131 6.5561 1.3962 9.5324
SCC-25 GDSC2 3.431 8.2694 0.7153 13.0639
SAT [Human HNSCC] GDSC2 3.6456 14.5294 -2.0144 26.9895
BHY GDSC2 3.6661 5.7809 2.1179 3.9196
OSC-19 GDSC2 3.7608 8.1994 1.0039 10.4913
PE/CA-PJ15 GDSC2 3.8093 5.5335 2.3273 2.4013
KOSC-2 GDSC2 3.8329 6.8064 1.7383 5.8625
CAL-33 GDSC2 3.9356 8.4432 1.253 11.3017
BICR 78 GDSC2 4.0471 6.5149 2.2819 4.7503
HO-1-N-1 GDSC2 4.1806 6.3874 2.4321 3.5714
HSC-2 GDSC2 4.2823 8.1642 1.647 8.0804
PCI-06A GDSC2 4.3663 6.7574 2.1008 2.7373
PCI-04B GDSC2 4.3886 8.1385 1.4754 6.2615
BICR 22 GDSC2 4.4047 7.4941 2.0546 5.3626
DOK GDSC2 4.6195 8.1313 1.8936 5.8796
HSC-4 GDSC2 4.6459 7.5742 2.1718 4.2103
CAL-27 GDSC2 4.8068 10.534 0.8659 11.4059
OSC-20 GDSC2 4.8607 7.5305 2.3195 3.0266
Ca9-22 GDSC2 5.366 14.9798 -0.9037 18.6304
SCC-9 GDSC2 5.4549 7.2785 2.7155 0.6142
PCI-30 GDSC2 5.4746 9.5649 1.7596 5.0822
SKN-3 GDSC2 5.5027 7.7501 2.554 1.1504
UPCI-SCC-090 GDSC2 5.9181 7.9921 2.6379 0.5868
SAS GDSC2 6.0484 7.7896 2.76 0.2509
LB771-HNC GDSC2 6.0757 8.3841 2.5562 0.7399
NCI-H3118 GDSC2 6.1951 8.5225 2.5532 0.6829
SCC-4 GDSC2 6.2113 7.7986 2.8146 0.1316
JHU-022 GDSC2 6.3824 8.5446 2.6181 0.4308
SCC-15 GDSC2 6.5198 8.6304 2.639 0.3393
FaDu GDSC2 7.3387 22.8915 -3.351 22.6757
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1710 GDSC2 1.8761 5.1601 1.031 19.291
CAL-29 GDSC2 2.8186 4.3743 2.3341 7.8899
RT-4 GDSC2 3.1889 5.3769 2.1816 7.6156
647V GDSC2 3.3621 4.5392 2.7465 3.5283
KU-19-19 GDSC2 3.7751 7.179 1.7568 8.6488
RT-112 GDSC2 4.0086 5.7782 2.6081 2.8696
BFTC-905 GDSC2 4.0736 6.7417 2.1907 5.2479
T24 GDSC2 4.3801 7.5399 1.7512 4.674
SW780 GDSC2 4.4717 6.2386 2.6736 1.7317
J82 GDSC2 4.5551 18.5228 -3.2769 28.2176
UM-UC-3 GDSC2 5.05 8.9963 1.763 5.8051
639V GDSC2 5.0903 6.4849 2.8627 0.3812
TCCSUP GDSC2 5.3287 7.0226 2.7595 0.5527
HT-1376 GDSC2 5.4779 7.6703 2.5744 1.0921
5637 GDSC2 5.7808 7.5076 2.7602 0.3379
HT-1197 GDSC2 6.4184 21.7252 -3.4439 24.6577
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW954 GDSC2 1.2961 3.6478 0.9306 19.0839
PA-1 GDSC2 1.4981 4.9135 0.7494 22.4242
Ca Ski GDSC2 1.7781 5.8094 0.6374 21.9053
LB831-BLC GDSC2 2.1405 5.8122 0.9938 18.4906
ACC-OV7 GDSC2 2.3397 9.5885 -0.8595 24.5101
PWR-1E GDSC2 2.5956 4.936 1.8513 11.6608
DoTc2 4510 GDSC2 2.6637 4.6248 2.0646 10.1066
KGN GDSC2 2.8308 5.157 1.9686 10.1106
TC-YIK GDSC2 2.9546 8.39 0.4756 18.6112
BPH-1 GDSC2 2.9791 7.9163 0.7332 17.1062
JAR GDSC2 3.0647 7.0799 1.0138 12.3131
ME-180 GDSC2 3.1292 7.4879 1.0763 14.6447
OV17R GDSC2 3.5496 5.7003 2.0759 4.433
OVCA433 GDSC2 3.5511 8.5056 0.6919 12.8757
OMC-1 [Human cervical carcinoma] GDSC2 3.5626 5.7026 2.084 4.3535
C-4-I GDSC2 3.5835 5.1307 2.6252 3.7069
C-33 A GDSC2 3.6638 8.137 1.1931 12.3881
UWB1.289 GDSC2 3.7808 6.2707 1.9607 4.626
DSH1 GDSC2 3.9416 6.9438 1.9979 6.7386
HeLa GDSC2 3.9688 8.2806 1.3589 10.5828
CAL-39 GDSC2 4.0311 7.9433 1.5723 9.1345
HEC-1 GDSC2 4.0465 5.9223 2.5647 3.0517
SiHa GDSC2 4.0718 7.4279 1.8554 7.3055
HEY GDSC2 4.1293 6.303 2.4386 3.6347
HT-3 GDSC2 4.2162 6.2584 2.5152 3.018
NCC-IT GDSC2 4.308 6.9308 2.2583 4.3477
SKN GDSC2 4.352 7.1376 2.1891 4.6703
NEC8 GDSC2 4.3555 13.7427 -1.0542 21.6959
MS751 GDSC2 4.4303 11.995 -0.1291 17.4736
OVCA420 GDSC2 4.8377 8.857 1.6927 6.6166
SKG-IIIa GDSC2 4.9145 13.8238 -0.6681 18.706
SW962 GDSC2 5.0257 6.6271 2.4725 0.4405
SW756 GDSC2 5.0927 6.6072 2.8183 0.5106
JEG-3 GDSC2 5.2177 6.9001 2.4484 0.413
JHOS-3 GDSC2 5.6699 7.7517 2.3154 0.5517
OVMIU GDSC2 5.7397 8.1946 2.4851 1.219
NT2-D1 GDSC2 5.8162 7.6257 2.7314 0.3904
SiSo GDSC2 5.908 8.436 2.4652 1.1593
PEO1 GDSC2 6.5412 8.4858 2.6969 0.2307
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 ClinicalTrials.gov (NCT01585701) Phase I Study of AT13148, a Novel AGC Kinase Inhibitor. U.S. National Institutes of Health.
2 Company report (Astex)