Details of the Drug

General Information of Drug (ID: DMYRUH2)

Drug Name
I-BET151
Synonyms GSK1210151A
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 415.4
Logarithm of the Partition Coefficient (xlogp) 2.7
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C23H21N5O3
IUPAC Name
7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-pyridin-2-ylethyl]-3H-imidazo[4,5-c]quinolin-2-one
Canonical SMILES
CC1=C(C(=NO1)C)C2=C(C=C3C(=C2)N=CC4=C3N(C(=O)N4)[C@H](C)C5=CC=CC=N5)OC
InChI
InChI=1S/C23H21N5O3/c1-12-21(14(3)31-27-12)16-9-18-15(10-20(16)30-4)22-19(11-25-18)26-23(29)28(22)13(2)17-7-5-6-8-24-17/h5-11,13H,1-4H3,(H,26,29)/t13-/m1/s1
InChIKey
VUVUVNZRUGEAHB-CYBMUJFWSA-N
Cross-matching ID
PubChem CID
52912189
ChEBI ID
CHEBI:95083
CAS Number
1300031-49-5
TTD ID
D0WU1S

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bromodomain-containing protein 2 (BRD2) TTDP48B BRD2_HUMAN Inhibitor [1]
Bromodomain-containing protein 3 (BRD3) TTHE657 BRD3_HUMAN Inhibitor [1]
Bromodomain-containing protein 4 (BRD4) TTRA6BO BRD4_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) OT25JBA3 F263_HUMAN Gene/Protein Processing [2]
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Gene/Protein Processing [3]
Aurora kinase B (AURKB) OTIY4VHU AURKB_HUMAN Gene/Protein Processing [4]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [4]
Carbonic anhydrase 9 (CA9) OTNA51XT CAH9_HUMAN Gene/Protein Processing [2]
Collagen alpha-1(I) chain (COL1A1) OTI31178 CO1A1_HUMAN Gene/Protein Processing [3]
Collagen alpha-1(V) chain (COL5A1) OT24078H CO5A1_HUMAN Gene/Protein Processing [3]
Collagen alpha-2(I) chain (COL1A2) OTY7G382 CO1A2_HUMAN Gene/Protein Processing [3]
Cyclin-dependent kinase 4 (CDK4) OT7EP05T CDK4_HUMAN Gene/Protein Processing [5]
Cyclin-dependent kinase 6 (CDK6) OTR95N0X CDK6_HUMAN Gene/Protein Processing [5]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Bromodomain-containing protein 4 (BRD4) DTT BRD4 3.27E-01 0.02 0.04
Bromodomain-containing protein 3 (BRD3) DTT BRD3 8.51E-01 -0.03 -0.13
Bromodomain-containing protein 2 (BRD2) DTT BRD2 6.53E-02 -0.05 -0.13
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 3.5534 7.3026 1.521 13.2163
EW-22 GDSC1 -0.5212 2.6745 -0.7148 48.2746
ES5 GDSC1 -0.2525 4.2406 -0.8636 46.0051
EW-11 GDSC1 -0.1947 4.0958 -0.7519 45.3471
TC-71 GDSC1 0.0038 6.4133 -1.4415 44.9424
HuO9 GDSC1 0.6669 4.7031 -0.0425 36.8286
NOS-1 [Human HNSCC] GDSC1 0.699 8.4561 -1.6613 41.2547
CHSA0108 GDSC1 0.8546 8.939 -1.7374 40.6056
MHH-ES-1 GDSC1; CTRP2 0.9804 5.8181 0.578 34.9796
CHSA0011 GDSC1 1.2227 7.3171 -0.613 35.6751
ES8 GDSC1 1.3858 5.5825 0.3435 30.616
EW-3 GDSC1 1.4175 6.2992 0.0522 31.8977
ES4 GDSC1 1.627 6.5012 0.1666 30.2186
SK-N-MC CTRP2 1.7346 6.6837 1.152 30.6493
ES7 GDSC1 1.9784 6.5984 0.4632 26.8481
A-673 GDSC1; CTRP2 2.2692 7.1857 1.5647 27.5837
HuO-3N1 GDSC1 2.5673 13.3225 -2.3204 34.7625
CAL-78 GDSC1; CTRP2 2.7589 6.9701 2.1693 23.975
EW-16 GDSC1 2.8975 7.133 1.052 19.0318
ES1 GDSC1 3.0077 7.0433 1.1933 17.6143
CADO-ES1 GDSC1; CTRP2 3.0601 6.3011 2.714 21.0996
CAL-72 GDSC1 3.1087 9.6745 -0.0338 24.5866
SW1353 CTRP2 3.3779 11.8452 0.7045 27.1618
SaOS-2 GDSC1; CTRP2 3.4053 8.1794 2.3927 21.296
NY GDSC1 3.429 9.9883 0.0775 22.8121
CHSA8926 GDSC1 3.6511 9.0804 0.7122 18.377
MG-63 GDSC1; CTRP2 3.7538 12.8001 0.6088 26.469
SJSA-1 GDSC1; CTRP2 3.9487 12.8375 0.7749 25.4718
H-EMC-SS GDSC1 4.1443 7.2202 2.0084 7.7013
EW-18 GDSC1 4.1525 8.0543 1.6072 10.6435
TC71 CTRP2 4.1571 11.1182 1.803 21.5065
SK-PN-DW GDSC1 4.1621 12.8174 -0.7451 24.197
EW-24 GDSC1 4.173 9.3633 0.9778 14.9361
EW-7 GDSC1 4.501 6.5765 2.5405 2.9783
G-292 clone A141B1 GDSC1; CTRP2 4.7032 8.2033 3.7131 12.7356
HOS GDSC1; CTRP2 4.8158 12.0395 1.9701 19.3258
SK-ES-1 GDSC1; CTRP2 5.1542 11.2635 2.6603 15.9262
U2OS GDSC1; CTRP2 5.5734 8.8121 4.2508 8.4997
EW-13 GDSC1 5.6456 8.6415 2.2581 2.8398
EW-1 GDSC1 5.6917 7.5177 2.7222 0.5833
ES6 GDSC1 5.8808 7.888 2.6614 0.6733
Hs 822.T CTRP2 7.2651 8.4884 5.6282 0.3926
Hs 888.T CTRP2 7.7648 13.4414 3.6629 7.1099
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 213 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 -0.1732 3.3379 -0.2372 41.5944
JK1 CTRP2 2.3348 6.2256 1.9451 26.0634
JM1 GDSC1; CTRP2 -0.935 4.7567 -1.2635 46.8663
SEM CTRP2 -4.7868 -2.1468 -4.787 71.9163
KMS-26 CTRP2 -4.0491 0.4583 -4.0789 66.1534
OPM-2 GDSC1; CTRP2 -3.8908 2.5658 -4.0842 63.6408
OCI-AML-3 GDSC1; CTRP2 -3.4835 -0.628 -3.4852 63.3554
MV4-11 GDSC1; CTRP2 -3.2893 -1.3774 -3.2893 62.1739
Pfeiffer CTRP2 -2.7801 3.2615 -2.9937 57.6791
P30/OHK GDSC1 -2.618 -0.4653 -2.6225 72.8661
EoL-1 GDSC1; CTRP2 -2.5556 1.3263 -2.5825 57.0757
KMS-12-BM CTRP2 -2.3518 0.3436 -2.3544 55.9084
MOLM-16 GDSC1; CTRP2 -2.304 0.6616 -2.3095 55.5722
HH [Human lymphoma] GDSC1; CTRP2 -2.2698 5.0695 -2.7827 54.3521
Kasumi-1 GDSC1; CTRP2 -2.2365 0.7335 -2.2423 55.1261
KMS-21-BM CTRP2 -2.1939 1.2275 -2.2095 54.8036
SK-MM-2 GDSC1; CTRP2 -2.0745 8.4922 -3.5874 52.6677
DG-75 GDSC1 -2 1.0764 -2.0612 64.5
THP-1 GDSC1; CTRP2 -1.8987 3.4716 -2.0813 52.6581
OCI-AML-2 GDSC1; CTRP2 -1.8897 0.3324 -1.8904 52.8543
697 GDSC1; CTRP2 -1.7357 0.8342 -1.7388 51.8264
Mino CTRP2 -1.6658 0.7404 -1.6677 51.3633
BC-1 GDSC1 -1.4984 1.6875 -1.5991 58.9771
EM-2 GDSC1; CTRP2 -1.4797 0.4488 -1.48 50.1264
RPMI-8866 GDSC1 -1.4513 1.4063 -1.5159 58.7682
NCI-H929 GDSC1; CTRP2 -1.3534 3.1604 -1.4626 49.3211
MOLM-13 GDSC1; CTRP2 -1.2681 1.5614 -1.2768 48.7243
NB4 GDSC1; CTRP2 -1.26 0.2534 -1.2601 48.6632
HAL-01 GDSC1 -1.0776 2.7297 -1.3316 54.0847
SET-2 CTRP2 -1.0165 2.7531 -1.0716 47.1149
LC4-1 GDSC1 -0.9836 1.7737 -1.0623 53.5141
MOLP-8 GDSC1; CTRP2 -0.9429 2.3475 -0.9708 46.5968
NU-DUL-1 GDSC1; CTRP2 -0.928 0.3553 -0.928 46.451
NALM-6 GDSC1; CTRP2 -0.9221 1.0759 -0.923 46.4139
SU-DHL-16 GDSC1 -0.9003 0.3038 -0.9008 52.7737
A3/Kawakami GDSC1; CTRP2 -0.8927 0.2501 -0.8927 46.2158
KMS-11 GDSC1; CTRP2 -0.8858 3.6527 -1.0252 46.3696
PF-382 GDSC1; CTRP2 -0.8664 2.3753 -0.8935 46.0909
Ki-JK CTRP2 -0.863 2.5429 -0.8986 46.0821
MOLT-13 GDSC1; CTRP2 -0.8624 2.1319 -0.8794 46.0472
BV-173 GDSC1; CTRP2 -0.8504 1.6328 -0.8554 45.9451
CMK GDSC1; CTRP2 -0.827 2.0163 -0.8398 45.8049
WSU-DLCL2 GDSC1; CTRP2 -0.8218 1.5843 -0.8259 45.7528
KMS-34 CTRP2 -0.8149 1.4475 -0.8175 45.7036
HuT 78 CTRP2 -0.7954 2.7146 -0.839 45.6502
NOMO-1 GDSC1; CTRP2 -0.7758 2.6306 -0.8134 45.5107
BL-41 GDSC1 -0.7316 1.6879 -0.7857 50.6347
KG-1 GDSC1 -0.7036 4.1573 -1.3248 50.2291
NU-DHL-1 CTRP2 -0.637 2.2106 -0.6519 44.5482
M-07e CTRP2 -0.6287 4.0462 -0.8059 44.7807
SIG-M5 CTRP2 -0.6285 1.1871 -0.629 44.4571
MLMA GDSC1 -0.6187 2.4169 -0.7696 49.3354
JJN-3 GDSC1; CTRP2 -0.6112 3.6788 -0.7362 44.5846
HEL GDSC1; CTRP2 -0.5998 1.7283 -0.6038 44.275
SKM-1 GDSC1; CTRP2 -0.5686 1.1392 -0.5689 44.0574
WSU-NHL GDSC1 -0.5266 1.8092 -0.5821 48.193
MM1.S CTRP2 -0.5199 4.5752 -0.7784 44.2181
CRO-AP2 GDSC1 -0.514 4.2703 -1.157 48.513
Karpas-45 GDSC1 -0.4307 2.2493 -0.5383 47.1336
MHH-CALL-4 CTRP2 -0.4296 1.891 -0.4342 43.1436
SU-DHL-6 GDSC1; CTRP2 -0.3883 1.9802 -0.3938 42.8713
PL21 CTRP2 -0.3866 3.5657 -0.4847 43.0741
GA-10 GDSC1; CTRP2 -0.3795 3.4269 -0.4624 42.9954
LP-1 GDSC1; CTRP2 -0.3773 6.9476 -1.2297 44.1746
Loucy GDSC1 -0.3212 3.4669 -0.6945 46.3421
Ri-1 CTRP2 -0.3113 2.6603 -0.3357 42.4093
NCO2 CTRP2 -0.3033 2.4541 -0.3191 42.3336
ST486 GDSC1; CTRP2 -0.2636 2.5351 -0.2814 42.0752
KHM-1B CTRP2 -0.2376 4.0313 -0.3851 42.2081
SU-DHL-10 GDSC1; CTRP2 -0.2236 0.6276 -0.2236 41.7584
A4/Fukuda GDSC1; CTRP2 -0.2046 3.4675 -0.2822 41.8346
KE-97 CTRP2 -0.1041 4.2671 -0.2773 41.3985
MN-60 GDSC1 -0.0784 6.4151 -1.5276 45.5919
P31/FUJ GDSC1; CTRP2 -0.0782 3.7097 -0.1743 41.048
KE-37 GDSC1; CTRP2 -0.0665 2.6713 -0.0848 40.7664
F-36P CTRP2 -0.0503 3.3139 -0.1064 40.7621
SU-DHL-5 GDSC1 -0.0428 1.6224 -0.0605 42.1494
CA46 GDSC1; CTRP2 -0.0318 4.0596 -0.1691 40.8443
SU-DHL-8 GDSC1; CTRP2 -0.0065 1.7291 -0.0073 40.3146
RS4;11 GDSC1; CTRP2 0.0074 4.8088 -0.2524 40.8726
L-540 GDSC1; CTRP2 0.018 4.1766 -0.1327 40.5517
TALL-1 [Human adult T-ALL] CTRP2 0.0318 3.4537 -0.0325 40.2411
Namalwa GDSC1; CTRP2 0.0461 5.4842 -0.3577 40.9348
SUP-T1 GDSC1; CTRP2 0.052 5.4064 -0.3328 40.8581
Daudi GDSC1; CTRP2 0.0522 3.6701 -0.0321 40.1596
MHH-PREB-1 GDSC1 0.0664 3.825 -0.3801 42.3709
Kasumi-2 CTRP2 0.0691 4.235 -0.0866 40.2304
DB GDSC1; CTRP2 0.1064 4.6294 -0.1116 40.1391
OCI-Ly3 CTRP2 0.1112 3.4047 0.055 39.6936
KMOE-2 GDSC1 0.1418 3.2244 -0.1225 40.9254
WIL2 NS GDSC1 0.1589 3.6295 -0.2186 41.1353
MOLT-16 GDSC1; CTRP2 0.187 2.6372 0.1753 39.0598
Jurkat GDSC1; CTRP2 0.2155 5.3723 -0.1467 39.7764
HC-1 GDSC1 0.223 6.5453 -1.2719 43.263
RL GDSC1; CTRP2 0.2371 2.3901 0.2319 38.7057
AMO1 GDSC1; CTRP2 0.2459 2.362 0.2412 38.6455
Mono-Mac-1 CTRP2 0.2865 5.4467 -0.0868 39.3513
OCI-AML-5 GDSC1; CTRP2 0.2903 2.324 0.2866 38.3466
RPMI-8226 GDSC1; CTRP2 0.2975 3.7442 0.2191 38.5225
Karpas-422 GDSC1; CTRP2 0.2975 5.7101 -0.1393 39.4286
GR-ST GDSC1 0.3385 4.5593 -0.3394 40.2001
JVM-3 GDSC1; CTRP2 0.3586 5.2596 0.0347 38.7721
MEG-01 GDSC1 0.3737 4.679 -0.3464 39.9727
RPMI-8402 GDSC1; CTRP2 0.3836 4.8591 0.1452 38.3933
TUR GDSC1 0.4374 4.4535 -0.1941 38.9926
DND-41 GDSC1; CTRP2 0.462 4.0736 0.3554 37.5161
KMS-27 CTRP2 0.4755 6.3287 -0.1131 38.6641
Karpas-1106P GDSC1 0.4867 3.9112 0.0489 37.6722
P12-Ichikawa GDSC1; CTRP2 0.5258 3.6953 0.4642 36.9596
NKM-1 GDSC1 0.5566 3.9336 0.1174 36.8801
SR GDSC1; CTRP2 0.5946 3.3441 0.5629 36.4095
Peer CTRP2 0.6437 4.1259 0.542 36.2998
MOLM-6 CTRP2 0.6558 5.6244 0.2729 37.0167
KMS-20 CTRP2 0.6924 9.8747 -1.1544 39.8497
RCH-ACV GDSC1; CTRP2 0.6932 3.8484 0.6256 35.8667
P32/ISH GDSC1 0.718 5.2488 -0.2065 37.1529
L-363 GDSC1; CTRP2 0.7412 4.8959 0.5251 35.9972
KMS-28BM CTRP2 0.7989 4.9055 0.5858 35.6095
MOTN-1 CTRP2 0.8074 6.7543 0.1206 36.8414
SUP-B15 CTRP2 0.8226 3.9156 0.7553 35.0065
OCI-Ly10 CTRP2 0.8278 7.1906 0.0017 37.0564
CTB-1 GDSC1 0.8459 5.9912 -0.3894 37.034
HEL 92.1.7 CTRP2 0.8491 2.3852 0.8483 34.6142
HuNS1 CTRP2 0.8948 4.838 0.702 34.9179
ARH-77 GDSC1 0.9215 6.0598 -0.3421 36.4049
BDCM CTRP2 0.923 6.691 0.2661 36.0443
Karpas-299 GDSC1; CTRP2 0.9503 5.1772 0.6955 34.7407
MOLT-4 GDSC1 1.0056 3.675 0.6895 30.9171
KYO-1 CTRP2 1.0119 5.4077 0.7121 34.4726
JURL-MK1 GDSC1; CTRP2 1.0535 3.9139 0.9984 33.4314
HL-60 GDSC1; CTRP2 1.0596 4.8514 0.8774 33.7979
OCI-M1 GDSC1; CTRP2 1.0601 2.2287 1.06 33.2064
Ku812 GDSC1; CTRP2 1.0877 5.3376 0.8103 33.9085
KMS-18 CTRP2 1.0892 6.7082 0.4418 34.9741
Jiyoye GDSC1 1.1035 5.4471 0.1122 33.4023
L-428 GDSC1; CTRP2 1.1174 4.1741 1.0391 33.0823
TF-1 CTRP2 1.1349 4.0801 1.0678 32.9293
ALL-SIL GDSC1; CTRP2 1.1355 4.5768 1.0047 33.132
HT GDSC1; CTRP2 1.1465 7.4703 0.2515 35.2798
AML-193 CTRP2 1.1501 5.3026 0.8858 33.4581
MC116 GDSC1; CTRP2 1.213 3.165 1.2053 32.2129
BALL-1 GDSC1 1.2186 3.5962 0.9462 28.0431
KCL-22 GDSC1; CTRP2 1.2649 5.8938 0.8687 33.1147
Granta-519 GDSC1; CTRP2 1.3083 8.3635 0.0985 35.105
Karpas-231 GDSC1 1.3245 6.0753 0.0608 32.3709
KM-H2 GDSC1; CTRP2 1.364 7.0045 0.6454 33.4392
Sc-1 GDSC1 1.364 7.2058 -0.422 34.2176
KO52 CTRP2 1.3914 8.615 0.0899 34.842
CTV-1 GDSC1 1.5308 3.5692 1.2945 23.945
OCI-Ly19 GDSC1; CTRP2 1.5368 7.8191 0.5476 33.1311
EHEB GDSC1; CTRP2 1.5378 9.5207 -0.1207 34.8653
Reh GDSC1; CTRP2 1.5481 5.3931 1.2987 30.7865
LAMA-84 GDSC1; CTRP2 1.6109 4.75 1.488 29.9491
CCRF-CEM GDSC1 1.6114 5.1232 0.7766 26.8863
PL-21 GDSC1 1.6175 7.1703 -0.1579 31.7987
MOLT-3 CTRP2 1.6601 4.1438 1.6143 29.3624
HPB-ALL CTRP2 1.6614 6.2068 1.2157 30.6839
KY821 GDSC1 1.6628 6.1017 0.3878 28.8736
Raji GDSC1; CTRP2 1.728 7.1359 0.9962 31.1634
QIMR-WIL GDSC1 1.7552 6.3494 0.3637 28.5236
Ramos.2G6.4C10 GDSC1 1.8342 6.5142 0.3635 28.1217
RPMI-6666 GDSC1; CTRP2 1.8448 6.0142 1.4694 29.2481
JeKo-1 GDSC1; CTRP2 1.8825 6.4266 1.3925 29.3835
Hs 445 GDSC1 2.0326 9.0906 -0.6967 32.0074
KOPN-8 GDSC1 2.0337 8.1742 -0.2467 30.1564
CML-T1 GDSC1; CTRP2 2.0443 7.6026 1.1725 29.5866
SUP-HD1 GDSC1; CTRP2 2.046 6.0093 1.6903 27.8544
CESS GDSC1 2.1044 8.2615 -0.2237 29.7262
SU-DHL-4 GDSC1; CTRP2 2.1253 5.1998 1.9648 26.6562
Mono-Mac-6 GDSC1; CTRP2 2.1529 11.5367 -0.3671 33.509
K-562 GDSC1; CTRP2 2.2244 8.2343 1.1247 29.1759
HDLM-2 GDSC1; CTRP2 2.2263 7.6592 1.3472 28.4467
SUP-T11 CTRP2 2.263 5.9724 1.9371 26.3156
EB1 CTRP2 2.3563 8.6899 1.0812 28.9096
Hs 611.T CTRP2 2.3608 8.5246 1.1532 28.6661
EJM GDSC1; CTRP2 2.3792 10.5548 0.3037 31.1355
U-937 CTRP2 2.3886 6.5161 1.9166 25.9963
VAL GDSC1 2.4481 8.0638 0.1885 26.1628
BE-13 GDSC1 2.4706 6.1358 1.1549 20.1603
SUP-M2 GDSC1; CTRP2 2.6534 5.3185 2.5136 23.0698
H9 GDSC1 2.7512 7.1715 0.903 20.6317
GDM-1 GDSC1; CTRP2 2.9883 7.9797 2.0358 23.7849
IM-9 GDSC1 2.9965 8.8797 0.2674 23.4424
U-698-M GDSC1 3.0468 6.1055 1.6947 13.7979
MJ CTRP2 3.273 7.9376 2.3534 21.8115
ATN-1 GDSC1 3.2805 8.1361 0.8802 18.6637
ML-2 GDSC1 3.3638 5.3676 2.3338 7.6412
DEL GDSC1; CTRP2 3.4782 8.9474 2.138 22.0433
L-1236 GDSC1; CTRP2 3.5532 7.7619 2.7202 19.6522
YT GDSC1 3.6027 7.6282 1.398 13.9386
HD-MY-Z CTRP2 3.6204 7.5225 2.8876 18.8302
MOLP-2 CTRP2 3.6519 9.1364 2.231 21.2314
VL51 GDSC1 3.7404 11.6546 -0.501 24.5171
U266B1 GDSC1; CTRP2 3.8486 11.8731 1.1455 24.5448
TK [Human B-cell lymphoma] GDSC1 3.8696 7.9669 1.4386 12.7475
Ci-1 CTRP2 3.8985 6.6602 3.5095 15.6919
SU-DHL-1 CTRP2 4.0854 11.634 1.4864 22.8014
ALL-PO GDSC1 4.0888 10.9918 0.1058 20.3799
RC-K8 GDSC1 4.2652 6.1218 2.6081 2.9916
ME1 CTRP2 4.271 11.0124 1.9626 20.646
EB2 GDSC1 4.6229 6.7229 2.5442 2.726
ROS-50 GDSC1 4.7114 9.0972 1.4941 9.8673
MHH-CALL-2 GDSC1 4.9105 6.5503 2.7615 1.0488
MHH-CALL-3 CTRP2 4.9564 12.961 1.6422 20.1912
ME1 GDSC1 5.0398 14.2531 -0.7864 21.7612
SUP-B8 GDSC1 5.0601 8.1948 2.1363 4.6008
Farage GDSC1 5.3152 6.9685 2.7742 0.6426
JVM-2 GDSC1; CTRP2 5.3206 17.7906 -0.4422 25.7618
KMM-1 CTRP2 5.6456 7.5668 4.9298 5.5164
Toledo CTRP2 6.1598 7.559 5.3809 2.5739
Karpas-620 GDSC1; CTRP2 6.2716 8.1869 5.1561 3.3175
P3HR-1 CTRP2 6.3408 13.0242 2.7983 12.9511
REC-1 CTRP2 6.5734 9.3948 4.787 4.3478
⏷ Show the Full List of 213 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 2.1503 9.1142 0.6898 30.74
TE8 CTRP2 3.8552 14.4192 -0.083 28.1657
KYSE-270 GDSC1 -0.441 5.6704 -1.6001 48.1742
OE21 GDSC1; CTRP2 0.6936 6.6886 0.0171 37.5209
TE-14 CTRP2 1.3372 7.909 0.3 34.4869
TE-5 GDSC1; CTRP2 1.3678 10.3254 -0.6367 36.5738
TE-4 GDSC1; CTRP2 1.3729 7.0738 0.6321 33.447
TE-10 GDSC1; CTRP2 2.4164 8.7259 1.1296 28.5729
TE-8 GDSC1 2.5523 8.2574 0.1867 25.7179
T.T GDSC1 3.2748 8.5222 0.6824 19.9385
OE33 GDSC1; CTRP2 3.6289 10.1164 1.761 23.008
TE-15 GDSC1 4.1167 6.5371 2.3188 5.4492
TE-11 GDSC1; CTRP2 4.2571 8.9083 2.9437 16.9228
TE-6 GDSC1; CTRP2 5.1035 9.9957 3.2386 13.7182
KYSE-70 GDSC1; CTRP2 5.6227 12.0049 2.7058 14.7418
KYSE-410 CTRP2 5.6936 10.7138 3.4113 11.7391
KYSE-520 GDSC1; CTRP2 5.7111 12.4001 2.5847 15.0358
OE19 GDSC1; CTRP2 5.9546 12.9314 2.5258 14.7723
COLO 680N GDSC1; CTRP2 6.0134 13.0803 2.5006 14.7534
KYSE-140 CTRP2 6.7315 13.7407 2.7528 12.4106
KYSE-30 CTRP2 7.1531 12.0818 3.8925 7.1056
TE-9 GDSC1; CTRP2 7.2213 12.9609 3.5113 8.5447
KYSE-150 GDSC1; CTRP2 7.4025 11.9519 4.1316 5.7612
EC-GI-10 GDSC1; CTRP2 7.4858 12.8502 3.7551 7.1519
KYSE-180 GDSC1; CTRP2 7.8572 12.7354 4.0622 5.4064
TE-1 GDSC1; CTRP2 7.8601 17.0638 1.9649 13.4474
KYSE-450 GDSC1; CTRP2 7.9222 17.5576 1.7679 14.0454
KYSE-510 GDSC1; CTRP2 8.1038 13.4833 3.8693 5.8328
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 6.4311 14.8636 1.9528 16.0081
PaTu 8988s CTRP2 -0.5566 15.8411 -5.0496 47.206
Panc 08.13 GDSC1; CTRP2 0.6317 3.7667 0.5689 36.2601
MZ-PC-1 GDSC1 0.6957 7.4328 -1.1893 40.266
HuP-T4 CTRP2 0.8003 5.1236 0.544 35.7272
Panc 02.03 GDSC1; CTRP2 1.3797 4.9546 0.6088 19.2882
MIA PaCa-2 CTRP2 1.6327 3.9319 1.6023 29.4931
KP-1N GDSC1 2.1742 6.0988 0.8904 23.3053
TCC-Pan2 CTRP2 2.1926 6.6005 1.6767 27.4387
BxPC-3 GDSC1; CTRP2 2.2672 8.7549 0.9608 29.5602
CFPAC-1 GDSC1; CTRP2 2.398 5.2174 2.2565 24.776
KP-3 GDSC1; CTRP2 2.4587 8.84 1.1267 28.4546
SNU-213 CTRP2 3.2023 8.338 2.1142 22.892
Panc 05.04 CTRP2 3.3972 9.3334 1.8841 23.1886
HuP-T3 GDSC1; CTRP2 3.4046 10.8141 1.215 25.478
PL4 GDSC1 3.4435 8.1757 0.9955 17.299
Hs 766T GDSC1; CTRP2 3.7282 11.9152 1.0099 25.2925
DAN-G GDSC1; CTRP2 3.9604 8.5437 2.8093 18.2124
Capan-1 CTRP2 3.9711 9.7472 2.2715 20.2465
Capan-2 GDSC1 3.9791 7.5143 1.745 10.1573
PaTu 8988t GDSC1; CTRP2 4.078 9.5584 2.4651 19.238
KP-4 GDSC1; CTRP2 4.4538 10.6655 2.3037 18.9261
PK-45H CTRP2 4.5481 11.4122 2.0303 19.7283
Panc 10.05 GDSC1; CTRP2 5.099 12.2924 2.1014 18.1987
HPAC GDSC1; CTRP2 5.1144 9.1695 3.6522 12.0008
SU.86.86 GDSC1; CTRP2 5.3755 9.1549 3.9017 10.3838
Panc 04.03 GDSC1; CTRP2 5.631 13.8706 1.7817 18.2277
PaTu 8902 GDSC1; CTRP2 5.6649 9.3715 4.0549 9.123
SNU-410 CTRP2 5.7064 8.4345 4.5572 6.9355
QGP-1 GDSC1; CTRP2 6.0079 12.4899 2.7912 13.6225
KP-2 GDSC1; CTRP2 6.115 11.9744 3.1381 12.0186
Panc 03.27 GDSC1; CTRP2 6.3573 12.8813 2.8831 12.5833
PK-59 CTRP2 6.4614 12.1207 3.3464 10.5183
PSN1 GDSC1; CTRP2 6.73 8.7618 5.2058 2.4004
SW1990 GDSC1; CTRP2 6.7527 11.5371 3.8637 7.8763
HPAF-II GDSC1; CTRP2 7.219 11.1172 4.4076 4.915
YAPC GDSC1; CTRP2 7.3303 14.3013 2.9325 10.6744
SUIT-2 GDSC1; CTRP2 7.5782 18.7084 0.9408 17.4043
AsPC-1 GDSC1; CTRP2 7.7577 20.0253 0.4254 18.6958
L3.3 CTRP2 8.5299 14.8519 3.4998 6.6985
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 74 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 3.7839 15.2765 -0.5686 29.5721
CHL-1 GDSC1 -1.6507 2.4537 -1.8948 59.5197
SH-4 GDSC1 -1.5657 6.3473 -3.0612 55.5766
G-361 GDSC1; CTRP2 -0.3398 4.3665 -0.5469 42.9867
LOX-IMVI GDSC1; CTRP2 -0.2123 1.8586 -0.2147 41.6904
WM35 GDSC1 -0.2046 4.0297 -0.7409 45.4105
G-mel GDSC1 -0.0458 4.5787 -0.7596 44.1722
MMAc-SF GDSC1 0.6975 5.3555 -0.2721 37.5322
451Lu GDSC1 0.9402 6.6456 -0.585 37.154
IGR-1 CTRP2 1.0909 10.1285 -0.8418 37.9094
MZ-MEL-7 GDSC1 1.1932 4.7658 0.4911 30.925
COLO 679 GDSC1 1.3066 7.3122 -0.5283 34.9232
COLO 792 GDSC1; CTRP2 1.4165 6.6746 0.8086 32.7782
CP66-MEL GDSC1 1.7571 7.4205 -0.1428 31.0249
GAK GDSC1 1.7737 6.6809 0.2258 29.1595
M14 GDSC1 1.8976 7.5931 -0.092 30.1015
HMV-II GDSC1 1.9428 8.8757 -0.6741 32.3293
Mel Ho GDSC1; CTRP2 2.0523 7.5847 1.1877 29.5124
CP50-MEL-B GDSC1 2.164 4.8551 1.4598 19.4416
WM1552C GDSC1 2.367 6.5657 0.8488 22.6716
SK-MEL-1 GDSC1; CTRP2 2.4386 7.2572 1.7223 26.5221
A-431 GDSC1 2.5914 6.9924 0.8472 21.679
MZ-MEL-2 GDSC1 2.8487 8.9173 0.1207 24.823
WM115 GDSC1; CTRP2 2.9444 7.1882 2.2921 22.9808
IPC-298 GDSC1; CTRP2 3.141 11.0524 0.8433 27.3806
Hs 852.T CTRP2 3.1493 7.8389 2.2624 22.4981
LB373-MEL-D GDSC1 3.1689 10.1267 -0.2088 25.2151
WM278 GDSC1 3.2051 7.0581 1.3556 15.6926
HMCB CTRP2 3.2096 8.0193 2.2534 22.3605
MeWo GDSC1; CTRP2 3.3289 10.0861 1.4753 24.8093
K029AX CTRP2 3.3869 9.3734 1.8558 23.318
COLO 783 GDSC1 3.3952 6.9962 1.5455 13.5987
SK-MEL-3 GDSC1; CTRP2 3.4405 7.8113 2.5813 20.4902
IST-MEL1 GDSC1 3.5288 7.9889 1.1585 15.886
Hs 936.T CTRP2 3.5897 9.86 1.84 22.8298
WM983B CTRP2 3.7242 14.1104 -0.0546 28.4173
VMRC-MELG GDSC1 3.7502 6.3627 2.142 7.8526
Hs 940.T GDSC1; CTRP2 3.8134 10.1108 1.9464 21.8582
A-388 GDSC1 3.9116 10.4962 0.2136 20.3872
UACC-257 GDSC1; CTRP2 3.9383 11.5941 1.3652 23.5851
COLO 741 CTRP2 4.0015 9.4858 2.4229 19.5947
Hs 938.T GDSC1 4.0857 11.6267 -0.2124 22.0135
COLO 800 GDSC1; CTRP2 4.1672 11.2075 1.7698 21.601
SK-MEL-30 GDSC1; CTRP2 4.2979 12.3744 1.3275 22.8221
LB2518-MEL GDSC1 4.4344 11.7588 -0.009 19.883
WM793 GDSC1; CTRP2 4.4811 11.2099 2.066 19.7554
IGR-37 GDSC1; CTRP2 4.6142 13.003 1.3115 22.1227
WM88 CTRP2 4.714 12.2939 1.7518 20.3551
Hs 294T CTRP2 4.8244 10.8151 2.5791 16.9902
CJM [Human melanoma] CTRP2 4.8395 9.8089 3.0832 14.9521
A2058 CTRP2 4.8854 7.1457 4.3713 9.6457
RVH-421 GDSC1; CTRP2 4.9127 8.1832 3.9301 11.3426
A101D GDSC1; CTRP2 4.983 7.8538 4.153 10.2677
WM1799 CTRP2 5.0455 11.3807 2.504 16.7803
HT-144 GDSC1; CTRP2 5.0625 10.6034 2.9025 15.1682
SK-MEL-31 GDSC1; CTRP2 5.0906 13.5032 1.4931 20.4144
SK-MEL-2 GDSC1; CTRP2 5.1807 20.5298 -1.9301 29.4551
Hs 944.T CTRP2 5.2052 11.732 2.4741 16.5425
WM266-4 CTRP2 5.2614 9.3179 3.7167 11.4028
COLO 829 GDSC1; CTRP2 5.9335 11.9053 3.021 12.8488
SK-MEL-24 GDSC1; CTRP2 5.9374 13.4657 2.2442 15.8885
A-375 GDSC1; CTRP2 6.0949 14.7054 1.7559 17.3753
SK-MEL-5 GDSC1; CTRP2 6.1349 12.4467 2.9183 12.8669
RPMI-7951 CTRP2 6.1398 12.1511 3.0702 12.2457
SK-MEL-28 GDSC1; CTRP2 6.2661 7.9609 5.2641 2.8763
UACC-62 GDSC1; CTRP2 6.3509 15.131 1.754 16.8812
MDA-MB-435S CTRP2 6.5483 17.0789 0.9412 19.2673
Mel JuSo GDSC1; CTRP2 6.8401 9.2138 5.0638 2.8154
Hs 688(A).T CTRP2 7.248 8.3259 5.6837 0.2697
WT2-iPS GDSC1; CTRP2 7.5079 15.0805 2.6804 11.3618
IGR-39 CTRP2 7.6024 18.5603 1.0327 17.0663
Hs 839.T CTRP2 8.2215 13.5674 3.9056 5.5403
Hs 895.T CTRP2 8.9715 26.659 -1.9367 22.818
EquiPSC Line K2 GDSC1 1.3474 8.1166 -0.8695 35.8833
⏷ Show the Full List of 74 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-26 GDSC1 1.0534 4.7825 0.3367 32.593
SK-GT-4 GDSC1 1.9693 7.3903 0.0739 28.9584
ESO-51 GDSC1 2.2408 7.7822 0.1372 27.3614
HCE-4 GDSC1 2.3682 7.4055 0.4395 25.1443
KYAE-1 GDSC1 2.607 7.8205 0.4522 24.0167
FLO-1 GDSC1 2.8102 6.2533 1.4106 16.8712
KYSE-50 GDSC1 2.9995 9.3626 0.0288 24.6945
OACP4 C GDSC1 3.4738 8.1368 1.0398 16.8922
KYSE-220 GDSC1 4.0854 7.2018 1.9756 8.115
TE-12 GDSC1 4.1993 7.7615 1.784 9.2118
OACM5.1 C GDSC1 4.3213 10.6404 0.4585 17.6726
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 2.3424 14.5318 -1.5751 35.445
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-10 GDSC1 -1.2195 8.4037 -3.5668 52.8891
GI-ME-N GDSC1 -1.0093 7.1298 -2.7991 52.0401
SK-N-BE(2)-M17 GDSC1 -0.0851 4.2807 -0.6962 44.3526
GOTO GDSC1 0.2289 5.4414 -0.8 42.2563
CHP-212 GDSC1; CTRP2 0.3689 4.9291 0.1155 38.5275
IMR-5 GDSC1 0.4041 5.9204 -0.8157 41.1208
SK-N-BE(2) CTRP2 0.6724 5.5819 0.3013 36.8783
KP-N-SI9s CTRP2 0.7134 5.5141 0.3623 36.5599
SJNB-12 GDSC1 0.8394 7.246 -0.96 38.8691
SJNB-7 GDSC1 1.0122 6.9077 -0.6321 36.8999
CHP-126 GDSC1; CTRP2 2.0396 6.4751 1.549 28.3561
SiMa GDSC1; CTRP2 2.1167 10.3251 0.1367 32.3768
Kelly GDSC1; CTRP2 2.6173 6.6492 2.1232 24.5662
SJNB-5 GDSC1 2.6892 9.0088 -0.0646 26.4183
SJNB-6 GDSC1 2.8122 10.9463 -0.923 29.6247
SJNB-14 GDSC1 3.3076 7.9514 0.9953 17.8042
SK-N-DZ GDSC1; CTRP2 3.3246 13.5802 -0.1755 29.7575
SJNB-13 GDSC1 3.3357 7.8935 1.0476 17.3482
SK-N-AS GDSC1; CTRP2 3.3901 10.6444 1.2795 25.3039
NH-6 CTRP2 3.5003 10.0707 1.654 23.728
TGW GDSC1 3.6931 7.0622 1.7514 11.0242
NH-12 GDSC1 3.7775 9.2983 0.7045 17.9844
SK-N-MC-IXC GDSC1 3.8073 5.3286 2.6886 3.4861
SK-N-FI GDSC1; CTRP2 3.8131 8.9787 2.4652 19.9222
NB1 GDSC1; CTRP2 3.8429 8.2135 2.8332 18.4312
SK-N-SH GDSC1; CTRP2 3.9658 11.0797 1.6378 22.5738
LA-N-6 GDSC1 4.1067 12.1485 -0.4556 23.0968
NB(TU)1 GDSC1 4.6214 6.8785 2.4743 3.1908
MHH-NB-11 CTRP2 4.8989 10.6269 2.7402 16.1853
KP-N-YN GDSC1; CTRP2 6.4197 9.7695 4.4846 5.8665
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 -1.2486 2.3771 -1.2879 48.6169
HuH-28 CTRP2 1.4703 6.3411 0.9685 32.1064
SNU-478 CTRP2 2.2931 7.8253 1.3562 28.2108
SNU-245 CTRP2 4.8961 11.662 2.2293 18.1731
SNU-308 CTRP2 5.5201 11.5398 2.8484 14.3894
SNU-869 CTRP2 6.0877 17.6016 0.3018 22.1344
HuCC-T1 GDSC1; CTRP2 6.3773 13.0788 2.8007 12.8731
SNU-1196 CTRP2 8.2485 14.6491 3.4113 7.4142
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 89 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EFM-19 GDSC1 -0.4799 4.5679 -1.2235 48.2621
MDA-MB-453 GDSC1; CTRP2 -0.1321 4.2953 -0.3118 41.5942
Evsa-T GDSC1 0.4541 4.0046 -0.0177 38.1847
OCUB-M GDSC1 1.0723 4.5097 0.4645 31.7967
CAL-85-1 GDSC1; CTRP2 1.2682 7.6952 0.3034 34.7169
CAL-148 CTRP2 1.3254 4.6879 1.1912 31.8832
DU4475 GDSC1; CTRP2 1.4588 6.5348 0.8979 32.3636
UACC-812 CTRP2 1.7661 10.3722 -0.2447 34.4181
HCC1428 GDSC1; CTRP2 1.8775 7.2991 1.1016 30.3457
HCC1569 GDSC1; CTRP2 1.957 6.7311 1.3789 29.1896
EFM-192A GDSC1 2.4436 8.7316 -0.1458 27.8516
HCC2157 GDSC1 2.5925 10.0226 -0.6541 29.4462
CAMA-1 GDSC1; CTRP2 2.621 12.4846 -0.3374 32.0746
HCC1187 GDSC1 2.6434 8.1497 0.3217 24.5967
MDA-MB-436 GDSC1 2.9116 10.9462 -0.8373 28.9158
Hs 578T GDSC1; CTRP2 2.9941 9.4143 1.4365 25.8711
HMC-1-8 CTRP2 3.0514 7.1085 2.4362 22.1408
COLO 824 GDSC1 3.0614 10.1147 -0.294 26.0272
MDA-MB-361 GDSC1; CTRP2 3.1389 8.8483 1.8318 24.0893
UACC-893 GDSC1 3.2013 14.091 -2.1635 32.2008
BT-483 GDSC1 3.2639 17.0172 -3.5741 35.2107
MCF-7 GDSC1; CTRP2 3.4255 10.8175 1.234 25.3592
MFM-223 GDSC1 3.5641 7.3565 1.5027 13.3128
MDA-MB-330 GDSC1 3.6005 9.8027 0.3106 20.9288
SK-BR-3 CTRP2 3.6424 9.0076 2.279 21.0771
HCC1500 GDSC1; CTRP2 3.7223 9.3245 2.2173 21.0957
HCC70 GDSC1 3.8101 6.4922 2.123 7.8139
HCC38 GDSC1; CTRP2 3.8749 9.5127 2.2844 20.4456
HCC1806 GDSC1; CTRP2 3.9996 7.6695 3.2273 16.4854
MDA-MB-175-VII GDSC1 4.0013 7.6233 1.7078 10.3652
BT-474 GDSC1; CTRP2 4.0824 9.1753 2.6466 18.5274
MDA-MB-415 GDSC1 4.1145 8.2163 1.4997 11.5339
ZR-75-30 GDSC1; CTRP2 4.4941 7.8704 1.9348 4.7848
MDA-MB-231 GDSC1; CTRP2 4.5352 11.7254 1.8655 20.364
AU565 CTRP2 4.6267 8.6501 3.4302 14.0629
HCC202 GDSC1; CTRP2 4.6822 12.8039 1.4716 21.4167
MRK-nu-1 GDSC1 4.7401 6.433 2.7291 1.4186
ZR-75-1 CTRP2 4.9175 11.2505 2.4514 17.2733
BT-549 GDSC1; CTRP2 4.955 13.4587 1.3943 21.0583
HCC1143 GDSC1; CTRP2 5.0872 10.3164 3.0663 14.4537
MDA-MB-157 GDSC1; CTRP2 5.4643 11.6517 2.7438 14.9243
HCC1395 GDSC1; CTRP2 5.5778 11.1919 3.0722 13.3667
HCC2218 GDSC1; CTRP2 5.6643 10.6054 3.4398 11.682
HCC1419 GDSC1; CTRP2 5.8044 12.0669 2.8309 13.8715
KPL-1 CTRP2 6.309 8.106 5.225 2.9661
MDA-MB-468 GDSC1; CTRP2 6.3673 13.4097 2.6272 13.5746
HDQ-P1 GDSC1; CTRP2 6.5142 10.1724 4.3576 6.2326
CAL-51 GDSC1; CTRP2 6.6547 10.8704 4.1192 6.9842
T-47D GDSC1; CTRP2 6.8389 14.131 2.6426 12.6491
JIMT-1 GDSC1; CTRP2 7.0677 11.3795 4.1741 6.0891
HCC1954 GDSC1; CTRP2 7.1924 12.6532 3.6411 8.0656
HCC1937 GDSC1; CTRP2 7.2446 15.5566 2.2477 13.4422
CAL-120 GDSC1; CTRP2 7.9454 14.3198 3.3638 8.027
BT-20 GDSC1; CTRP2 8.0926 14.338 3.4554 7.4596
Hs 578Bst CTRP2 8.1573 18.9874 1.2383 15.4692
BT 416 CTRP2 1.3629 8.1374 0.2427 34.5491
BT 428 CTRP2 2.2511 10.105 0.3711 31.3372
BT 231 CTRP2 5.1286 14.0703 1.2449 21.1779
BT 248 CTRP2 5.7873 18.7427 -0.5203 25.0012
BT 139 CTRP2 6.1261 17.2982 0.4854 21.5112
BT 172 CTRP2 6.2047 12.1761 3.1111 11.9559
BT 239 CTRP2 6.5242 21.317 -1.1958 25.2376
BT 245 CTRP2 6.5658 10.046 4.4598 5.7189
BT 359 CTRP2 6.5808 10.9109 4.0425 7.4298
BT 145 CTRP2 6.6509 14.3357 2.3927 13.9518
BT 112 CTRP2 6.6661 16.6052 1.2728 17.9522
BT 330 CTRP2 6.7392 10.0351 4.5943 4.878
BT 271 CTRP2 6.7821 12.418 3.4495 9.527
BT147 CTRP2 6.9213 13.635 2.9529 11.2856
BT 340 CTRP2 6.9686 9.244 5.1336 2.3687
BT 286 CTRP2 7.0183 10.5765 4.5297 4.7142
BT 320 CTRP2 7.0835 9.018 5.3083 1.5714
BT 504 CTRP2 7.1721 13.2199 3.3476 9.284
BT 228 CTRP2 7.1884 11.6136 4.146 6.0191
BT 131 CTRP2 7.2316 12.5664 3.7121 7.7155
BT 422 CTRP2 7.2669 12.4165 3.8108 7.2603
BT 333 CTRP2 7.2743 10.0467 4.9517 2.6909
BT 187 CTRP2 7.4675 18.4242 0.9968 17.4155
BT 232 CTRP2 7.5693 15.1424 2.6952 11.2053
BT 224 CTRP2 7.6121 13.9075 3.3304 8.6557
BT164 CTRP2 7.6294 16.7953 1.9259 13.9669
BT 482 CTRP2 7.6748 9.1584 5.5468 0.3852
BT 498 CTRP2 7.7206 14.5125 3.1129 9.3459
BT 328 CTRP2 7.7638 8.7565 5.7262 0.0662
BT 444 CTRP2 7.7915 14.5857 3.1277 9.1796
BT 159 CTRP2 7.7969 17.7603 1.5751 14.9223
BT 179 CTRP2 7.827 15.5346 2.6904 10.8132
BT 440 CTRP2 8.0316 15.1872 3.0045 9.2964
BT 216 CTRP2 8.3004 15.9228 2.8355 9.5469
⏷ Show the Full List of 89 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 2.9314 10.4921 0.8909 27.8182
Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GI-1 GDSC1 -0.9052 3.0039 -1.2085 52.2959
H4 GDSC1 -0.0015 8.6474 -2.4436 46.0458
MOG-G-UVW GDSC1 -0.0004 4.0334 -0.5204 43.2796
SNU-466 CTRP2 0.025 3.6716 -0.061 40.3431
D-566MG GDSC1 0.8821 5.9866 -0.3502 36.6717
M059J GDSC1 1.0592 4.7308 0.3636 32.4174
SF539 GDSC1; CTRP2 1.1882 5.1135 0.9667 33.073
D-263MG GDSC1 1.624 6.5836 0.1251 30.4411
D-423MG GDSC1 1.6887 7.207 -0.1064 31.2041
SK-MG-1 GDSC1 1.7301 4.9205 0.987 24.9111
KS-1 [Human Krukenberg tumour] GDSC1 1.8154 8.0716 -0.4014 31.8533
D283 Med GDSC1; CTRP2 1.9868 5.8278 1.6734 28.1009
DK-MG GDSC1; CTRP2 1.9911 7.4941 1.1548 29.8122
M059K CTRP2 2.1368 7.2329 1.4051 28.5335
MOG-G-CCM GDSC1 2.3911 8.0089 0.1637 26.5451
KG-1-C CTRP2 2.5909 7.9652 1.6199 26.4174
Onda 10 GDSC1 2.6962 8.0127 0.4367 23.7245
LN-405 GDSC1 2.7614 8.692 0.1566 24.9931
D-542MG GDSC1 2.8231 9.6763 -0.28 26.8969
LNZTA3WT4 GDSC1 2.8884 7.7917 0.7162 21.252
D-392MG GDSC1 3.1148 8.2775 0.6694 20.6351
SNU-626 CTRP2 3.238 7.2358 2.5901 21.0312
D-502MG GDSC1 3.2386 9.1274 0.3495 22.0434
D-336MG GDSC1 3.2867 8.0085 0.9492 18.1885
LN-18 GDSC1; CTRP2 3.3466 8.2184 2.315 21.7485
42-MG-BA GDSC1; CTRP2 3.4413 11.5415 0.9098 26.3609
Onda 11 GDSC1 3.4932 10.5843 -0.1675 23.8197
T98G GDSC1; CTRP2 3.6346 8.4711 2.5069 20.2391
D-247MG GDSC1 3.8806 8.2117 1.3257 13.5147
YH-13 GDSC1; CTRP2 4.0195 12.1665 1.1668 24.0437
KNS-81-FD GDSC1 4.4435 10.9978 0.3739 17.7784
Becker GDSC1; CTRP2 4.6063 11.4821 2.0505 19.5158
SNU-201 CTRP2 4.6947 15.3337 0.232 25.3026
KALS-1 GDSC1; CTRP2 4.6961 10.6671 2.5316 17.4736
SF268 GDSC1; CTRP2 4.7464 9.7398 3.0283 15.3914
SNU-1105 CTRP2 4.8306 13.1329 1.4439 21.1704
AM-38 GDSC1 4.9083 7.3566 2.4229 3.003
Hs 683 GDSC1; CTRP2 5.0133 11.1636 2.5818 16.5493
SW1088 GDSC1; CTRP2 5.0672 15.094 0.6815 23.1292
KINGS-1 GDSC1 5.2213 12.4585 0.2234 16.3661
GaMG GDSC1; CTRP2 5.6713 13.0458 2.2281 16.4926
CAS-1 GDSC1; CTRP2 5.8772 19.3601 -0.7534 25.4113
SW1783 GDSC1; CTRP2 6.0113 8.2254 4.9262 4.7644
SNU-738 CTRP2 6.0604 6.9986 5.5805 1.9191
8-MG-BA GDSC1; CTRP2 6.2039 12.0408 3.1781 11.6853
ONS-76 GDSC1; CTRP2 6.2101 13.7564 2.3256 15.0404
Daoy GDSC1; CTRP2 6.3172 13.4961 2.5433 13.9967
A-172 GDSC1; CTRP2 6.404 13.2586 2.7324 13.0926
GOS-3 CTRP2 6.501 16.4046 1.2398 18.3757
U-251MG GDSC1; CTRP2 6.8594 15.2845 2.0848 14.7272
LN-229 GDSC1; CTRP2 6.8938 18.6573 0.4311 20.2078
GMS-10 CTRP2 6.978 17.6902 0.9801 18.341
YKG-1 GDSC1; CTRP2 7.0593 14.0947 2.8306 11.5298
U-87MG ATCC GDSC1; CTRP2 7.2548 25.9481 -2.9176 27.5465
TM-31 CTRP2 7.3057 15.874 2.1371 13.7471
SF295 GDSC1; CTRP2 7.3577 9.715 5.1536 1.8422
U-118MG GDSC1; CTRP2 7.3781 13.2124 3.5019 8.3338
SNU-489 CTRP2 7.3915 16.8415 1.7233 15.0917
GB-1 GDSC1; CTRP2 7.4977 13.3278 3.5313 8.0311
KNS-60 CTRP2 7.5679 18.2443 1.1629 16.6998
CCF-STTG1 CTRP2 7.6297 11.4432 4.5241 3.8994
SF126 GDSC1; CTRP2 7.6953 15.5176 2.6033 11.3535
NMC-G1 GDSC1; CTRP2 7.949 9.5377 5.5177 0.334
DBTRG-05MG GDSC1; CTRP2 8.2269 16.8712 2.3244 11.5636
SNB-75 GDSC1; CTRP2 8.45 13.3813 4.134 4.3963
KNS-42 GDSC1; CTRP2 9.0238 16.229 3.1693 7.3089
KNS-81 CTRP2 9.2233 23.9184 -0.4016 18.6981
⏷ Show the Full List of 67 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1 0.4534 3.8962 0.0176 38.0421
ETK-1 GDSC1 1.1408 9.0068 -1.494 38.6545
TGBC1TKB GDSC1 3.9396 8.2922 1.3309 13.2858
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-7 CTRP2 0.4097 4.3667 0.2586 37.9875
HEC-1-B CTRP2 0.6723 11.3663 -1.8039 40.8835
JHUEM-3 CTRP2 1.4936 7.6743 0.5538 33.2592
HEC-251 CTRP2 2.4346 8.0672 1.4137 27.5869
HEC-151 CTRP2 2.5331 5.142 2.4157 23.7927
ESS-1 GDSC1; CTRP2 3.0538 7.865 2.1509 23.1791
MFE-280 GDSC1 3.0768 5.4101 2.0672 10.812
JHUEM-2 CTRP2 3.3327 10.1265 1.4607 24.8492
KLE GDSC1; CTRP2 3.3649 8.7594 2.1037 22.4785
HEC-6 CTRP2 3.5362 9.3996 1.9955 22.4096
EFE-184 CTRP2 3.5961 10.8361 1.3932 24.3733
JHUEM-1 CTRP2 4.1748 8.4452 3.0714 16.6309
HEC-59 CTRP2 4.5516 10.0097 2.7127 17.108
HEC-1-A CTRP2 5.2934 10.4222 3.2019 13.4466
RL95-2 GDSC1; CTRP2 5.502 12.7709 2.219 16.8817
HEC-50B CTRP2 5.8586 10.4617 3.679 10.2954
HEC-265 CTRP2 6.5457 10.8768 4.0322 7.5334
MFE-296 GDSC1; CTRP2 6.5981 15.947 1.5467 17.142
MFE-319 GDSC1; CTRP2 6.6506 16.8137 1.1563 18.3706
HEC-108 CTRP2 6.828 7.9973 5.6177 0.7322
EN GDSC1; CTRP2 6.9048 10.3226 4.573 4.7081
AN3-CA GDSC1; CTRP2 8.0577 15.0533 3.0875 8.938
Ishikawa (Heraklio) 02 ER- CTRP2 6.6544 10.0663 4.5164 5.3364
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-21 GDSC1 0.6058 10.042 -2.5034 43.0656
SW13 GDSC1 0.8545 9.0481 -1.7895 40.7085
LB2241-RCC GDSC1 0.8569 6.6611 -0.6761 37.9335
CAL-54 GDSC1; CTRP2 0.8822 7.1241 0.0829 36.6587
LB996-RCC GDSC1 1.0103 6.4955 -0.4464 36.2662
TK-10 GDSC1 1.2261 6.1939 -0.0921 33.6181
HA7-RCC GDSC1 1.862 8.1696 -0.405 31.645
BB65-RCC GDSC1 1.9656 7.24 0.1429 28.6302
LB1047-RCC GDSC1 2.5352 6.8543 0.8638 21.8185
KTCTL-195 GDSC1 2.7945 7.3838 0.8363 20.8814
VMRC-RCW CTRP2 2.8247 8.9 1.4837 26.1961
769-P GDSC1; CTRP2 3.0297 7.8937 2.1139 23.3831
TUHR14TKB CTRP2 3.1099 7.679 2.2839 22.5313
KTCTL-1M GDSC1 3.1537 8.1565 0.763 19.9
KTCTL-140 GDSC1 3.335 7.0395 1.4741 14.3449
VMRC-RCZ GDSC1; CTRP2 3.4517 9.9267 1.6713 23.798
A-704 GDSC1 3.7456 8.9532 0.8511 17.1704
NCC010 GDSC1 3.7999 6.7592 1.9836 8.9148
KTCTL-26A GDSC1 3.9678 7.459 1.7639 10.0514
SN12C GDSC1 4.2075 9.7589 0.8084 15.9147
UO-31 GDSC1; CTRP2 4.3149 11.623 1.709 21.4559
NCC021 GDSC1 4.5831 8.8346 1.5327 9.9438
A-498 GDSC1; CTRP2 4.7315 8.2087 3.7388 12.5618
KTCTL-13 GDSC1 4.7346 8.0493 2.0062 6.2005
SW156 GDSC1 5.0897 9.8843 1.3712 9.7284
TUHR10TKB CTRP2 5.5292 8.2933 4.4662 7.7
RXF 393L GDSC1 5.6751 8.0027 2.5317 1.3627
BFTC-909 GDSC1; CTRP2 5.8854 12.249 2.8087 13.7967
OS-RC-2 GDSC1; CTRP2 5.9956 12.8626 2.5945 14.4228
SNU-1272 CTRP2 6.038 13.5416 2.2904 15.5122
ACHN GDSC1; CTRP2 6.0875 14.8869 1.659 17.7357
786-O GDSC1; CTRP2 6.3303 15.2503 1.6775 17.1934
TUHR4TKB CTRP2 6.7398 10.2034 4.5121 5.216
KMRC-20 GDSC1; CTRP2 6.7719 14.8966 2.209 14.4241
KMRC-2 CTRP2 6.8411 14.1366 2.6415 12.6493
KMRC-1 GDSC1; CTRP2 7.1928 18.3709 0.8101 18.4967
Caki-1 GDSC1; CTRP2 7.3957 20.4159 -0.0486 20.6986
RCC10RGB CTRP2 7.6644 17.8478 1.4325 15.6327
Caki-2 CTRP2 8.4391 14.3663 3.6697 6.1669
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-C2B GDSC1 0.7664 7.5883 -1.1905 39.8731
NCI-H716 GDSC1; CTRP2 0.9635 6.2941 0.4294 35.459
SW626 GDSC1 1.0175 7.3644 -0.8376 37.5239
CCK-81 GDSC1; CTRP2 1.0311 6.0225 0.5792 34.7951
SNU-407 GDSC1; CTRP2 1.2881 5.522 0.9865 32.6684
CaR-1 GDSC1 1.4227 11.1 -2.2446 39.0034
NCI-H747 GDSC1; CTRP2 1.4958 6.5394 0.9369 32.1184
HCC2998 GDSC1 1.5677 10.3125 -1.7248 37.2375
HT115 GDSC1; CTRP2 1.6789 5.0377 1.5125 29.6434
SW48 GDSC1; CTRP2 1.975 8.5534 0.7338 31.1611
LoVo GDSC1; CTRP2 1.9754 8.2268 0.8628 30.7737
SW1417 GDSC1; CTRP2 2.047 8.739 0.7353 30.929
SW1116 GDSC1; CTRP2 2.0864 8.1751 1.0012 29.9964
SW837 GDSC1 2.2073 11.7901 -1.8735 34.9763
CL-11 GDSC1; CTRP2 2.2457 7.8575 1.2933 28.5641
SNU-C1 GDSC1; CTRP2 2.3786 7.5737 1.5423 27.3235
MDST8 GDSC1; CTRP2 2.4583 7.0485 1.8169 26.1322
CW-2 GDSC1; CTRP2 2.501 8.004 1.5091 27.0651
DiFi GDSC1 2.6809 7.5293 0.6627 22.4503
SNU-175 CTRP2 2.7516 7.7278 1.8832 25.0202
HCT 15 GDSC1; CTRP2 2.7544 5.2948 2.6273 22.3528
LS411N GDSC1; CTRP2 2.8681 6.8236 2.3378 23.0402
RCM-1 [Human ESC] GDSC1; CTRP2 2.9322 7.0247 2.3375 22.8517
HCT 8 CTRP2 3.0581 5.7483 2.8611 20.5772
NCI-H508 GDSC1; CTRP2 3.1865 8.6261 1.9762 23.4378
SNU-C5 GDSC1; CTRP2 3.2393 10.6146 1.1434 26.1603
LS180 GDSC1; CTRP2 3.6471 10.4227 1.6368 23.3994
COLO 320HSR GDSC1 3.697 7.6757 1.4491 13.2458
GP5d GDSC1 3.769 9.4084 0.6428 18.3929
SW1463 GDSC1 3.8282 10.9931 -0.1003 22.3154
SNU-81 GDSC1 3.9925 7.258 1.881 9.0998
LS1034 GDSC1; CTRP2 4.0415 11.4327 1.5415 22.7201
SNU-C2A CTRP2 4.3261 10.3258 2.3448 19.0797
SNU-61 GDSC1; CTRP2 4.3342 10.0427 2.4877 18.512
COLO 320 CTRP2 4.3751 10.3346 2.3877 18.7963
COLO 678 GDSC1; CTRP2 4.4229 11.6685 1.7884 20.9108
GP2d CTRP2 4.4324 13.7081 0.7982 24.2209
RKO GDSC1; CTRP2 4.814 12.4212 1.7804 20.0216
SNU-503 CTRP2 4.8278 13.4281 1.2954 21.6834
HT-55 GDSC1; CTRP2 4.8663 10.0367 2.9979 15.2329
T84 GDSC1; CTRP2 4.9457 10.0606 3.0605 14.7981
SNU-1040 GDSC1 4.9803 10.2106 1.1424 11.5197
COLO201 CTRP2 5.1624 9.2673 3.6496 11.9023
DLD-1 CTRP2 5.2162 8.6201 4.0147 10.2762
COLO205 GDSC1; CTRP2 5.2773 8.9539 3.9096 10.5703
LS513 GDSC1; CTRP2 5.5315 11.0402 3.1072 13.322
HCC-56 CTRP2 5.7419 9.2511 4.1824 8.4295
SW620 GDSC1; CTRP2 5.8457 9.8513 3.9729 9.0946
C2BBe1 GDSC1; CTRP2 5.9251 13.5289 2.2023 16.0715
SK-CO-1 GDSC1; CTRP2 6.056 12.1593 2.9966 12.7059
OUMS-23 CTRP2 6.1182 9.5168 4.3693 6.8993
HCT 116 GDSC1; CTRP2 6.5386 8.246 5.3233 2.1997
SW948 GDSC1; CTRP2 6.5654 21.1787 -1.0931 24.9175
LS123 GDSC1; CTRP2 6.7182 16.1573 1.538 16.9474
HT-29 GDSC1; CTRP2 7.1829 11.2485 4.3192 5.3246
KM12 GDSC1; CTRP2 7.1955 13.2284 3.3607 9.1931
SNU-C4 CTRP2 7.2682 11.7439 4.1389 5.9284
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 3.3521 9.4873 0.2643 22.0913
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-7 GDSC1 0.7115 5.8382 -0.4617 38.1147
Li-7 CTRP2 0.8618 8.0587 -0.266 37.546
SNU-878 CTRP2 1.0027 6.178 0.5051 35.1071
JHH-1 GDSC1; CTRP2 1.2319 3.9108 0.8568 18.65
HLE GDSC1 1.5387 6.3618 0.1442 30.7977
JHH-5 CTRP2 2.2528 7.2372 1.5288 27.7565
SNU-387 GDSC1; CTRP2 2.7529 9.6548 1.0836 27.7234
Hep-G2/C3A GDSC1 2.9036 10.4445 -0.5937 27.9607
SNU-182 CTRP2 3.157 10.5374 1.0967 26.5378
Huh-7 GDSC1 3.4649 9.0204 0.591 19.7884
HuH-1 GDSC1; CTRP2 4.3384 10.3081 2.3651 18.9724
JHH-4 GDSC1; CTRP2 4.4553 10.3766 2.4443 18.3841
Hep 3B2.1-7 GDSC1; CTRP2 4.5117 15.0197 0.2231 25.7493
JHH-2 GDSC1; CTRP2 4.5322 12.2825 1.5901 21.3555
Hep-G2 CTRP2 4.5424 11.2451 2.1063 19.459
SNU-761 CTRP2 5.0915 15.3508 0.5751 23.4016
SNU-423 GDSC1; CTRP2 5.0918 12.4584 2.0126 18.5455
SNU-398 GDSC1; CTRP2 5.172 10.3222 3.1411 13.9613
SNU-886 CTRP2 6.0212 7.9572 3.429 0.7129
SNU-449 GDSC1; CTRP2 6.7068 15.829 1.6926 16.4258
PLC/PRF/5 CTRP2 6.8628 11.5232 3.9535 7.3219
JHH-6 GDSC1; CTRP2 7.2813 8.3198 5.6998 0.2219
SNU-475 CTRP2 8.5204 15.2088 3.325 7.3772
SK-HEP-1 GDSC1; CTRP2 9.1757 15.4832 3.6089 5.505
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 210 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SBC-1 GDSC1 -0.8003 2.4715 -0.9764 51.3331
RERF-LC-KJ GDSC1 -0.7886 1.7896 -0.8572 51.2933
SBC-3 GDSC1 -0.7781 5.3948 -1.8505 50.7653
NCI-H211 GDSC1; CTRP2 -0.5168 2.733 -0.5514 43.795
DV-90 CTRP2 -0.3508 6.0844 -0.9459 43.6848
UMC-11 GDSC1 -0.2213 1.6141 -0.245 44.3894
NCI-H1694 GDSC1; CTRP2 -0.1869 3.7232 -0.2911 41.7806
EBC-1 GDSC1; CTRP2 0.0619 4.9291 -0.2173 40.5672
NCI-H1184 CTRP2 0.1818 1.8118 0.1813 39.059
NCI-H847 GDSC1 0.2386 3.6026 -0.1236 40.1828
NCI-H810 GDSC1; CTRP2 0.2727 5.8223 -0.1952 39.6539
EMC-BAC-2 GDSC1 0.3523 5.0057 -0.4953 40.5902
NCI-H146 GDSC1; CTRP2 0.5561 4.1601 0.4445 36.9091
NCI-H1155 GDSC1; CTRP2 0.5888 3.4519 0.5498 36.4711
COR-L105 GDSC1; CTRP2 0.6196 8.8805 -0.8353 39.5688
HCC44 GDSC1; CTRP2 0.6502 6.3821 0.062 37.5763
COR-L32 GDSC1 0.9282 4.886 0.1628 34.2297
NCI-H2227 GDSC1 1.0205 4.4478 0.433 32.285
DMS 53 GDSC1; CTRP2 1.0381 6.4567 0.4629 35.0981
LXF 289 GDSC1; CTRP2 1.0727 5.2415 0.8149 33.9467
IST-SL1 GDSC1 1.2224 5.358 0.2736 31.9117
NCI-H1734 CTRP2 1.2546 6.1131 0.7982 33.365
IST-SL2 GDSC1 1.2547 3.6587 0.9657 27.7052
NCI-H596 GDSC1 1.2949 5.8425 0.1354 32.1819
NCI-H290 GDSC1 1.349 6.4266 -0.0747 32.8558
Lu-99A GDSC1 1.4229 3.6549 1.1498 25.5283
NCI-H522 GDSC1; CTRP2 1.5444 8.7564 0.1967 34.0547
NCI-H23 GDSC1; CTRP2 1.5831 6.6309 1.0037 31.6188
Lu-134-A GDSC1 1.6551 5.2334 0.7732 26.672
NCI-H2087 GDSC1; CTRP2 1.661 8.1794 0.5456 32.7232
NCI-H1666 GDSC1; CTRP2 1.6677 9.2553 0.1252 33.8307
HCC95 CTRP2 1.6805 7.486 0.8228 31.8507
BEN GDSC1; CTRP2 1.7868 3.9125 1.7634 28.4431
NCI-H1693 GDSC1; CTRP2 1.8183 6.2101 1.3861 29.612
NCI-H2722 GDSC1 1.8895 7.5465 -0.0771 30.0718
LUDLU-1 CTRP2 1.8921 6.2745 1.448 29.1673
NCI-H2347 GDSC1 2.0376 8.0474 -0.1811 29.8441
Lu-99 CTRP2 2.0419 6.3771 1.5811 28.24
EPLC-272H GDSC1; CTRP2 2.0548 6.6002 1.5269 28.3829
Sq-1 CTRP2 2.0592 6.1885 1.6551 27.9328
LK-2 GDSC1 2.0994 9.7757 -0.9729 32.7115
VMRC-LCD GDSC1; CTRP2 2.1322 8.2794 1.009 29.8286
Lu-135 GDSC1 2.1419 3.9042 1.8388 16.8205
LCLC-97TM1 GDSC1; CTRP2 2.1582 5.9497 1.8288 27.0218
CPC-N GDSC1 2.1675 4.9698 1.4115 19.7714
COR-L51 CTRP2 2.1796 10.8368 -0.0252 32.5997
NCI-H209 GDSC1; CTRP2 2.2033 19.5586 -4.1308 39.3569
LC-2/ad GDSC1 2.2137 6.303 0.8306 23.5011
NCI-H1975 GDSC1; CTRP2 2.2622 7.8131 1.3278 28.3999
NCI-H520 GDSC1; CTRP2 2.2826 6.5272 1.7977 26.7398
NCI-H358 GDSC1; CTRP2 2.3136 6.6383 1.7964 26.6483
NCI-H2595 GDSC1 2.3154 7.0372 0.5707 24.6233
NCI-H526 GDSC1; CTRP2 2.4175 7.2816 1.6907 26.6957
NCI-H1703 GDSC1; CTRP2 2.524 9.3964 0.9597 28.7868
NCI-H1341 GDSC1; CTRP2 2.5254 5.4861 2.3407 24.0786
RERF-LC-Sq1 GDSC1 2.5374 7.9318 0.3344 24.983
COR-L279 GDSC1 2.5477 5.5334 1.5194 17.2091
LC-1/sq GDSC1 2.5611 8.4363 0.106 26.1012
NCI-H2810 GDSC1 2.5889 8.6892 0.0054 26.4932
NCI-H2009 GDSC1; CTRP2 2.6137 11.2294 0.2359 30.6306
COR-L321 GDSC1 2.6225 7.4965 0.6265 22.9212
NCI-H647 CTRP2 2.674 10.025 0.8396 28.7152
NCI-H2731 GDSC1 2.675 6.0209 1.4015 17.5117
NCI-H2369 GDSC1 2.6805 7.8655 0.4957 23.45
NCI-H2081 GDSC1; CTRP2 2.7714 10.5548 0.7013 28.8504
SW1271 GDSC1; CTRP2 2.8071 11.9182 0.1104 30.4158
NCI-H2803 GDSC1 2.818 6.9927 1.0513 19.3653
LOU-NH91 GDSC1; CTRP2 2.8234 7.8689 1.9048 24.7329
Lu-139 GDSC1 2.8597 6.3367 1.4139 16.6419
COR-L88 GDSC1; CTRP2 2.8699 8.3941 1.7426 25.1711
SK-LU-1 GDSC1; CTRP2 2.9616 7.3664 2.245 23.1027
SK-MES-1 GDSC1; CTRP2 3.0121 11.3645 0.5707 28.5565
NCI-H835 GDSC1 3.0678 9.0188 0.2591 23.2065
NCI-H3255 GDSC1 3.0873 8.2887 0.6405 20.9203
NCI-H2029 GDSC1; CTRP2 3.0881 9.6878 1.4116 25.6904
NCI-H524 GDSC1 3.1208 8.8731 0.377 22.3411
EMC-BAC-1 GDSC1 3.2036 8.5884 0.5895 20.7775
HCC366 GDSC1; CTRP2 3.2361 9.2945 1.7371 24.1547
NCI-H1648 GDSC1 3.3084 5.8677 2.0377 10.1617
NCI-H1876 GDSC1 3.3095 8.0151 0.965 17.9987
ABC-1 GDSC1 3.3422 8.5313 0.7341 19.3632
ChaGo-K-1 GDSC1; CTRP2 3.3632 10.1031 1.502 24.6247
NCI-H1755 GDSC1; CTRP2 3.3734 8.451 2.2449 21.9344
Calu-3 GDSC1; CTRP2 3.3774 8.868 2.0692 22.5707
NCI-H2804 GDSC1 3.383 7.1485 1.4593 14.2774
Ms-1 GDSC1 3.3871 7.429 1.3224 15.2499
NCI-H446 GDSC1; CTRP2 3.4324 11.0534 1.1306 25.6794
NCI-H2461 GDSC1 3.4382 10.2948 -0.0681 23.5254
NCI-H1373 CTRP2 3.4632 9.6773 1.7963 23.3241
NCI-H2373 GDSC1 3.5479 9.3517 0.4932 20.0694
NCI-H720 GDSC1 3.5796 9.8807 0.2547 21.3146
SHP-77 GDSC1; CTRP2 3.5811 8.5413 2.4211 20.708
NCI-H2818 GDSC1 3.5827 7.8382 1.2773 14.8682
NCI-H69 GDSC1; CTRP2 3.5881 9.5501 1.9798 22.328
NCI-H1436 GDSC1 3.5945 5.6456 2.3787 6.5064
NCI-H2405 GDSC1; CTRP2 3.6074 9.0768 2.2124 21.4194
NCI-H1304 GDSC1 3.6075 6.7816 1.8239 10.7614
LB647-SCLC GDSC1 3.6397 8.6914 0.8972 17.2421
NCI-H345 GDSC1 3.6846 8.7099 0.9239 16.9109
Lu-65 GDSC1; CTRP2 3.7151 8.1077 2.746 19.1105
NCI-H2291 GDSC1; CTRP2 3.7506 11.0345 1.4508 23.7735
NCI-H1105 GDSC1; CTRP2 3.753 8.5241 2.6056 19.5455
NCI-H513 GDSC1 3.8285 10.288 0.2515 20.4617
NCI-H2106 CTRP2 3.8653 11.3286 1.4221 23.5768
DMS 454 CTRP2 3.8712 8.658 2.6676 18.9942
NCI-H82 GDSC1 3.8798 5.556 2.6286 3.7467
HCC2279 CTRP2 3.8845 9.4433 2.3259 20.2641
NCI-H1836 GDSC1 3.9217 9.295 0.8193 16.775
NCI-H2066 GDSC1 3.9282 8.3078 1.3145 13.4377
NCI-H1299 GDSC1; CTRP2 3.9643 10.7647 1.7863 22.0502
NCI-H2591 GDSC1 3.9846 10.1809 0.4278 18.9383
NCI-H1869 GDSC1; CTRP2 4.0007 9.4874 2.4214 19.6025
HCC1833 CTRP2 4.0079 9.6339 2.3606 19.8151
NCI-H1395 CTRP2 4.0095 13.024 0.7414 25.4233
A-427 GDSC1 4.0169 8.1542 1.4577 12.1383
NCI-H2170 GDSC1; CTRP2 4.0714 8.8907 2.7658 18.0928
DMS 79 GDSC1; CTRP2 4.0739 7.2108 3.4921 15.2606
NCI-H1435 GDSC1; CTRP2 4.0909 7.9733 3.1932 16.3733
NCI-H2795 GDSC1 4.1045 9.692 0.7633 16.5267
HCC15 GDSC1; CTRP2 4.1231 10.8164 1.915 21.1856
COLO 668 GDSC1; CTRP2 4.154 8.9646 2.8149 17.69
NCI-H1993 GDSC1 4.1581 13.1391 -0.9084 24.8884
NCI-H1048 GDSC1 4.1655 7.1482 2.058 7.2709
NCI-H441 GDSC1; CTRP2 4.2007 9.3717 2.6733 18.1242
NCI-H2110 GDSC1; CTRP2 4.2085 9.8477 2.4579 18.9376
NCI-H1944 GDSC1; CTRP2 4.2228 10.464 2.1794 19.9598
NCI-H1568 GDSC1; CTRP2 4.252 10.5247 2.1785 19.8912
NCI-H1437 GDSC1 4.2654 9.7502 0.8562 15.4297
RERF-LC-A1 CTRP2 4.2799 11.0769 1.94 20.7071
NCI-H187 GDSC1 4.285 8.0991 1.6806 9.7213
NCI-H650 GDSC1; CTRP2 4.2955 11.5232 1.7391 21.396
NCI-H2342 GDSC1; CTRP2 4.3224 7.836 3.4915 14.593
NCI-H1770 GDSC1 4.3295 8.865 1.3386 12.0223
PaCa-3 GDSC1 4.3408 7.8638 1.8338 8.4471
NCI-H1781 GDSC1 4.3479 6.3165 2.5687 3.0932
COR-L23 GDSC1 4.3501 14.7099 -1.5395 26.6732
Lu-165 GDSC1 4.4157 9.668 1.0079 13.9921
HOP-62 GDSC1; CTRP2 4.456 11.5311 1.8863 20.4768
NCI-H1688 GDSC1 4.6557 14.2493 -1.0739 24.0446
PC-14 GDSC1; CTRP2 4.6824 10.3681 2.6639 16.9886
NCI-H1581 GDSC1; CTRP2 4.71 10.5153 2.6185 17.1018
NCI-H1650 GDSC1; CTRP2 4.7237 12.985 1.4202 21.4976
NCI-H1915 GDSC1; CTRP2 4.7424 11.3314 2.2504 18.4463
LK2 CTRP2 4.7847 10.8672 2.5167 17.3251
NCI-H2141 GDSC1 4.8066 6.712 2.6459 1.7982
DMS 114 GDSC1; CTRP2 4.8466 11.3155 2.3544 17.8093
A-549 GDSC1; CTRP2 4.8484 11.6802 2.1768 18.4806
NCI-H1339 CTRP2 4.8616 10.3178 2.8566 15.8088
NCI-H2126 CTRP2 4.9586 10.6817 2.7686 15.9366
MOR/CPR CTRP2 5.0732 8.2509 4.055 10.4465
NCI-H2869 GDSC1 5.1246 10.0717 1.3052 10.0791
NCI-H2172 GDSC1; CTRP2 5.1274 8.8267 3.8308 11.2377
DMS 273 GDSC1; CTRP2 5.1503 17.0072 -0.1988 25.4844
HCC1588 CTRP2 5.1818 9.9748 3.321 13.2066
NCI-H322 CTRP2 5.2053 10.3976 3.1343 13.915
NCI-H661 GDSC1; CTRP2 5.2076 10.0972 3.2844 13.299
LC-1/sq-SF CTRP2 5.2448 13.3688 1.6962 19.3591
NCI-H1651 GDSC1; CTRP2 5.2995 12.6275 2.1132 17.7142
NCI-H2085 GDSC1; CTRP2 5.3039 13.8184 1.5242 19.8376
RERF-LC-MS GDSC1; CTRP2 5.4298 9.0723 3.992 9.8895
IA-LM GDSC1; CTRP2 5.4377 14.2173 1.442 19.8351
COR-L95 GDSC1; CTRP2 5.4482 9.1059 3.9922 9.8484
NCI-H2228 GDSC1; CTRP2 5.5387 14.0609 1.6073 19.0436
SW1573 GDSC1; CTRP2 5.5425 12.6374 2.3208 16.4085
NCI-H1838 GDSC1; CTRP2 5.6089 14.2275 1.5845 18.9757
NCI-H2030 GDSC1; CTRP2 5.6557 12.3955 2.5393 15.3277
NCI-H2023 GDSC1; CTRP2 5.6713 9.8688 3.813 10.1191
NCI-H1623 GDSC1; CTRP2 5.703 13.419 2.0689 17.0252
T3M-10 CTRP2 5.7048 13.5414 2.0092 17.243
NCI-H1573 GDSC1; CTRP2 5.7521 12.3009 2.6694 14.619
NCI-H838 GDSC1; CTRP2 5.796 11.6714 3.0213 13.1237
NCI-H322M GDSC1 5.8783 8.4414 2.4499 1.5431
NCI-H2135 GDSC1 5.9419 7.7111 2.7484 0.3814
NCI-H1092 GDSC1 5.9594 7.4326 2.8507 0.1624
COLO 699 CTRP2 5.9617 13.8107 2.0921 16.4114
HCC2108 CTRP2 6.1038 12.6573 2.7873 13.4499
NCI-H2196 CTRP2 6.1641 7.4478 5.4398 2.3196
NCI-H889 CTRP2 6.2242 9.6877 4.3703 6.6967
HOP-92 GDSC1; CTRP2 6.2409 13.5514 2.4534 14.491
Calu-6 GDSC1; CTRP2 6.2507 9.2682 4.601 5.6804
NCI-H841 GDSC1; CTRP2 6.3247 12.1532 3.2203 11.2853
NCI-H1793 GDSC1; CTRP2 6.4021 14.8751 1.9235 16.1703
HCC827 GDSC1; CTRP2 6.5306 11.543 3.689 8.9841
NCI-H727 GDSC1; CTRP2 6.5578 16.9882 0.9942 19.0779
RERF-LC-Ad2 CTRP2 6.5977 11.7583 3.6345 9.0902
NCI-H2122 GDSC1; CTRP2 6.6325 8.4849 5.2727 2.269
HCC78 GDSC1; CTRP2 6.7756 14.0643 2.6263 12.8255
NCI-H2444 GDSC1; CTRP2 6.7772 11.8457 3.7295 8.3876
HCC2935 CTRP2 6.971 8.8549 5.3157 1.6689
NCI-H1355 GDSC1; CTRP2 6.9733 12.068 3.7673 7.9051
CAL-12T GDSC1; CTRP2 7.1135 13.81 3.0126 10.72
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 7.1942 13.6041 3.1748 9.94
HCC1438 CTRP2 7.2201 15.4306 2.2915 13.321
HCC4006 CTRP2 7.3454 11.4052 4.3554 4.9444
LCLC-103H GDSC1; CTRP2 7.3468 8.6793 5.5896 0.4463
NCI-H196 GDSC1; CTRP2 7.3529 15.4131 2.4008 12.6838
SBC-5 GDSC1; CTRP2 7.3554 8.3091 5.7331 0.1377
NCI-H1792 GDSC1; CTRP2 7.5251 13.2913 3.5685 7.8405
EKVX GDSC1; CTRP2 7.5872 15.2075 2.6764 11.2484
HCC1195 CTRP2 7.6502 11.5754 4.4752 4.0629
NCI-H1563 GDSC1; CTRP2 7.7167 14.294 3.2165 8.9455
RERF-LC-Ad1 CTRP2 7.7351 18.1323 1.3452 15.8087
NCI-H292 GDSC1; CTRP2 7.7525 15.1146 2.842 10.349
NCI-H226 GDSC1; CTRP2 7.8542 17.0615 1.9617 13.4684
NCI-H2286 CTRP2 7.8891 9.8154 5.3848 0.6721
NCI-H460 GDSC1; CTRP2 8.1932 9.2717 5.7011 0.0408
Calu-1 CTRP2 8.4151 9.9577 5.5458 0.1571
HCC1171 CTRP2 10.1195 20.7883 1.7291 10.9873
KNS-62 GDSC1; CTRP2 10.3209 20.1255 2.1686 9.2586
Hs 888.Lu CTRP2 4.9307 12.3356 1.9285 19.2171
⏷ Show the Full List of 210 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 1.0915 5.774 -0.0421 34.1764
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 0.2991 2.8963 0.2809 38.3335
H-STS CTRP2 1.9752 5.9587 1.6266 28.2976
P-STS CTRP2 2.3676 6.7187 1.8293 26.3668
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 1.0283 8.7569 -0.3519 37.1346
OC 314 GDSC1; CTRP2 0.0403 4.8925 -0.2333 40.6925
FU-OV-1 GDSC1; CTRP2 0.3719 6.0352 -0.1436 39.1414
RMG-I GDSC1; CTRP2 2.1153 9.1275 0.6476 30.9723
OVCAR-4 GDSC1; CTRP2 2.2977 6.446 1.8392 26.5489
OVCAR-3 GDSC1 2.3766 7.1297 0.5825 24.2739
OV-90 GDSC1; CTRP2 2.4309 6.3415 2.0159 25.5168
TOV-21G GDSC1 2.6994 5.8143 1.5252 16.501
MCAS CTRP2 3.0725 7.1069 2.4594 21.9938
SK-OV-3 GDSC1; CTRP2 3.0767 10.0581 1.234 26.314
OAW28 GDSC1; CTRP2 3.1398 10.4478 1.1205 26.5087
Caov-3 CTRP2 3.2357 8.6357 2.0232 23.1304
ONCO-DG-1 CTRP2 3.3788 9.8065 1.6527 24.0602
COV434 CTRP2 3.6919 9.9678 1.8924 22.3708
JHOC-5 CTRP2 3.7367 8.8313 2.4534 20.1687
TYK-nu GDSC1; CTRP2 3.7463 9.7431 2.0501 21.6529
Caov-4 GDSC1 3.7972 8.2911 1.2215 14.5201
ES-2 GDSC1 3.8112 12.0961 -0.6643 24.9942
IGROV-1 GDSC1; CTRP2 3.8468 8.497 2.7137 18.8813
OVK18 GDSC1; CTRP2 3.8599 12.3207 0.9409 25.1757
Kuramochi GDSC1; CTRP2 3.8894 11.1259 1.542 23.1025
A2780 GDSC1; CTRP2 4.1825 10.5276 2.1101 20.3187
SNU-8 CTRP2 4.2715 10.2588 2.3242 19.2926
COV644 CTRP2 4.3846 11.7716 1.7023 21.3111
OVCAR-5 GDSC1; CTRP2 4.5205 12.5147 1.4655 21.8171
OVKATE GDSC1 4.5881 8.5296 1.6827 8.8699
OV7 CTRP2 4.8549 9.3909 3.2997 14.0415
OVCAR-8 GDSC1; CTRP2 5.0189 7.9627 4.1378 10.2407
OVTOKO GDSC1; CTRP2 5.2319 12.9629 1.8867 18.6996
JHOS-2 GDSC1; CTRP2 5.408 14.9791 1.0362 21.2612
EFO-21 GDSC1; CTRP2 5.5099 12.4948 2.3636 16.3135
OVSAHO CTRP2 5.5993 13.8525 1.7635 18.3595
HEY A8 CTRP2 5.6194 13.9697 1.7222 18.4653
TOV-112D GDSC1; CTRP2 5.6954 11.1989 3.1709 12.7216
SNU-119 CTRP2 5.9988 11.8 3.1285 12.2842
COV362 CTRP2 6.0048 12.9223 2.5724 14.4909
OAW42 GDSC1; CTRP2 6.0838 9.8032 4.1977 7.685
EFO-27 GDSC1; CTRP2 6.8744 13.515 2.9762 11.2748
DOV13 GDSC1; CTRP2 6.9399 9.3433 5.0682 2.6624
OVISE GDSC1; CTRP2 7.361 9.5965 5.2085 1.6422
ES2 CTRP2 7.4289 10.7922 4.7013 3.4655
JHOM-1 CTRP2 7.6604 14.9102 2.8755 10.3641
OV56 GDSC1; CTRP2 7.8056 8.7206 5.7527 0.0401
SNU-840 CTRP2 7.8363 14.651 3.1276 9.1122
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 2.0991 4.9089 1.9872 26.6637
Yamato-SS CTRP2 3.7417 7.8523 2.8811 18.5205
SW872 GDSC1 -1.2835 1.2862 -1.3282 57.0685
VA-ES-BJ GDSC1 -0.4091 4.1467 -1.0016 47.4919
Rh41 GDSC1; CTRP2 -0.0385 2.6847 -0.0567 40.5799
Hs 633.T GDSC1 0.278 5.5432 -0.7899 41.8953
KYM-1 GDSC1; CTRP2 0.4561 4.5902 0.2724 37.7734
G-401 GDSC1; CTRP2 0.5939 7.0988 -0.2219 38.4502
G-402 GDSC1; CTRP2 1.1012 6.3014 0.5774 34.5509
STS-0421 GDSC1 1.5523 7.9105 -0.574 33.8236
MFH-ino GDSC1 1.7422 7.2795 -0.0896 30.8577
A-204 GDSC1; CTRP2 1.8203 8.4349 0.6165 31.9997
Rh18 GDSC1; CTRP2 2.2083 6.6691 1.6721 27.4056
RD GDSC1; CTRP2 2.4785 8.7841 1.1707 28.2537
Rh30 GDSC1 2.5738 7.0677 0.7941 22.095
EW-8 GDSC1 2.9902 6.5851 1.4063 16.1662
TTC-709 CTRP2 3.4512 13.1277 0.1629 28.5293
TE 617.T CTRP2 3.647 9.8942 1.8816 22.528
SW684 GDSC1 3.7477 8.7238 0.9671 16.4086
SK-LMS-1 GDSC1; CTRP2 4.3896 12.8065 1.2016 23.0231
RKN GDSC1; CTRP2 4.5443 9.8027 2.8048 16.7625
HT-1080 GDSC1; CTRP2 4.7393 10.6386 2.5859 17.161
TE 441.T CTRP2 5.0095 9.3908 3.4462 13.0858
GCT GDSC1; CTRP2 5.1577 10.2939 3.1419 13.9898
SW982 GDSC1; CTRP2 5.3228 12.276 2.3085 16.9244
BT-12 CTRP2 6.3192 11.1489 3.7174 9.2497
MES-SA GDSC1; CTRP2 6.4941 11.1698 3.8461 8.398
BT-16 CTRP2 6.5276 8.5903 5.1483 2.9302
Tm87-16 CTRP2 6.6315 9.6533 4.7028 4.6019
SK-UT-1 GDSC1; CTRP2 6.9084 15.9321 1.8009 15.6702
Hs 729.T CTRP2 9.311 17.2326 2.8819 8.0017
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 3.9198 9.6812 2.2513 20.454
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 GDSC1; CTRP2 1.6408 6.6559 1.0587 31.2546
NCI-H28 GDSC1; CTRP2 1.9137 5.7111 1.6229 28.5072
NCI-H2452 GDSC1 2.3671 7.3448 0.4682 24.9848
NCI-H2052 CTRP2 4.4989 12.9273 1.2431 22.6243
MPP 89 GDSC1; CTRP2 4.6038 11.4186 2.0791 19.415
MSTO-211H CTRP2 5.0582 9.9281 3.2298 13.8562
ACC-MESO-1 CTRP2 6.9875 9.7612 4.901 3.2616
JL-1 CTRP2 8.0695 15.6453 2.809 9.9892
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; CTRP2 -0.3955 2.7608 -0.4276 42.9863
LNCaP clone FGC GDSC1; CTRP2 0.4999 6.0376 -0.0047 38.3149
PC-3 GDSC1 1.5581 7.9298 -0.5776 33.8082
DU145 GDSC1; CTRP2 5.5124 12.8911 2.1682 17.0515
22Rv1 GDSC1; CTRP2 6.0311 15.7499 1.1806 19.4935
PaCa-3 CTRP2 7.1264 11.275 4.2668 5.6217
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 3.0597 10.4408 1.0433 26.9788
A-253 GDSC1; CTRP2 6.8455 13.7368 2.8437 11.8499
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 3.4352 9.6 0.2768 21.7153
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-620 CTRP2 -0.7705 2.8359 -0.8213 45.4983
SNU-16 CTRP2 0.1441 4.0907 0.0144 39.6735
GSS CTRP2 0.1958 1.8492 0.1952 38.9661
NUGC-4 GDSC1; CTRP2 0.3207 5.7918 -0.135 39.3258
SNU-1 GDSC1; CTRP2 0.5432 6.4915 -0.0871 38.3413
Fu97 GDSC1; CTRP2 0.6494 3.615 0.6007 36.0986
ECC10 GDSC1; CTRP2 0.7894 4.1021 0.6998 35.2969
HGC-27 GDSC1; CTRP2 1.5078 8.3906 0.301 33.9037
SK-GT-2 GDSC1 1.9809 6.7504 0.393 27.2294
HSC-39 GDSC1 2.0974 5.2439 1.2161 21.4923
RERF-GC-1B GDSC1 2.22 7.054 0.4734 25.6319
OCUM-1 CTRP2 2.2799 10.2387 0.3421 31.3295
SNU-719 CTRP2 2.5119 8.6329 1.2681 27.8367
NCI-N87 GDSC1; CTRP2 2.6157 6.4819 2.1745 24.3877
MKN74 CTRP2 2.7494 8.761 1.4638 26.4825
KE-39 CTRP2 3.4662 10.791 1.2865 25.0762
KATO III GDSC1; CTRP2 3.6463 7.658 2.8606 18.861
TMK-1 GDSC1 3.8223 9.5225 0.6282 18.2989
IM95 GDSC1; CTRP2 3.87 10.0726 2.02 21.4424
SNU-5 GDSC1; CTRP2 3.938 10.8298 1.7298 22.3186
SNU-601 CTRP2 4.0831 11.1927 1.6964 22.0717
Hs 746.T GDSC1; CTRP2 4.1374 11.5421 1.5802 22.3463
HuG1-N CTRP2 4.1675 14.753 0.0417 27.0687
AGS CTRP2 4.4014 8.1845 3.4181 14.6777
SCH GDSC1 4.4766 8.6532 1.5465 10.1409
GSU CTRP2 4.7958 7.0486 4.3192 10.0886
RF-48 GDSC1 4.8166 6.9209 2.5625 2.2815
NUGC-3 GDSC1; CTRP2 4.985 12.0954 2.0963 18.4725
TGBC11TKB GDSC1 5.5092 7.2045 2.7648 0.5505
SH-10-TC CTRP2 5.8937 13.3227 2.2789 15.8447
ECC12 CTRP2 6.5099 14.6898 2.1032 15.304
23132/87 GDSC1; CTRP2 6.8034 15.2597 2.053 14.9461
LMSU CTRP2 6.856 15.0951 2.1763 14.3938
SNU-668 CTRP2 6.8667 8.7256 5.3114 1.8084
MKN7 GDSC1; CTRP2 7.1032 14.4565 2.6848 12.0227
MKN45 GDSC1; CTRP2 7.2806 8.6131 5.5858 0.4945
SNU-216 CTRP2 8.0798 12.2154 4.4449 3.6603
MKN1 GDSC1; CTRP2 9.8776 27.5411 -1.7009 20.9554
SNG-M GDSC1; CTRP2 2.6569 7.923 1.7066 25.9205
SNU-685 CTRP2 3.7783 12.6432 0.7078 26.1077
SNU-1077 CTRP2 4.229 8.9418 2.9004 17.1644
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC1 -0.572 4.3391 -1.2432 49.0535
HTC-C3 GDSC1 0.1133 3.3816 -0.1962 41.4149
K5 GDSC1 0.678 4.126 0.1829 35.7514
8305C GDSC1; CTRP2 1.1456 6.0355 0.7006 34.0359
IHH-4 GDSC1 1.4664 4.2641 0.9796 26.3987
CAL-62 GDSC1; CTRP2 1.7953 11.0913 -0.53 34.9727
ASH-3 GDSC1 1.9851 7.8384 -0.1284 29.8501
BHT-101 GDSC1; CTRP2 2.0919 10.0826 0.2169 32.2426
CGTH-W-1 GDSC1; CTRP2 2.6531 5.8414 2.3968 23.4815
WRO GDSC1 3.2253 8.3039 0.75 19.7058
SW579 CTRP2 3.317 9.2906 1.8215 23.6318
FTC-238 CTRP2 3.8602 9.4281 2.3085 20.3927
TT GDSC1; CTRP2 4.1744 8.1064 3.2213 16.0433
8505C GDSC1; CTRP2 4.209 11.3182 1.7562 21.5465
B-CPAP GDSC1; CTRP2 4.4998 11.7775 1.807 20.6597
ML-1 [Human leukemia] GDSC1; CTRP2 4.8838 10.8925 2.5962 16.7866
FTC-133 GDSC1; CTRP2 5.2359 10.4692 3.1267 13.8784
TT2609-C02 GDSC1; CTRP2 5.8453 15.6869 1.0562 20.2808
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Ca9-22 GDSC1 -0.855 3.1164 -1.182 51.775
BICR 78 GDSC1 -0.7538 5.2755 -1.7788 50.5891
PCI-04B GDSC1 -0.5413 3.2057 -0.8629 48.5894
HO-1-N-1 GDSC1 -0.385 6.0142 -1.6802 47.8179
BB49-HNC GDSC1 0.0505 4.9643 -0.8007 43.53
SAS GDSC1 0.4758 5.7353 -0.6628 40.2437
JHU-011 GDSC1 0.5438 15.7749 -5.3482 45.7217
PCI-38 GDSC1 0.5562 5.6867 -0.5584 39.4132
SKN-3 GDSC1 0.6289 5.8062 -0.5336 38.8705
LB771-HNC GDSC1 0.772 6.5293 -0.703 38.5175
KOSC-2 GDSC1 0.8018 3.996 0.3619 34.0437
DOK GDSC1 0.9579 5.8482 -0.2118 35.683
OSC-19 GDSC1 1.0397 5.8748 -0.1395 34.9
Detroit 562 GDSC1; CTRP2 1.0677 6.7543 0.404 35.1541
NCI-H3118 GDSC1 1.1215 5.3599 0.1682 33.0284
YD-10B CTRP2 1.1569 5.6077 0.8231 33.6278
KON GDSC1 1.2162 5.4909 0.2097 32.2691
HO-1-u-1 GDSC1 1.3281 5.7014 0.2319 31.5174
JHU-029 GDSC1 1.3432 7.1635 -0.4225 34.3298
SCC-15 GDSC1 1.447 8.8775 -1.1397 36.2228
JHU-022 GDSC1 1.6128 6.8756 -0.023 31.2099
PCI-06A GDSC1 1.9718 7.3692 0.0865 28.8834
SNU-1214 CTRP2 2.0659 8.1007 1.008 30.0397
BICR 18 CTRP2 2.3216 6.163 1.9487 26.0918
OSC-20 GDSC1 2.4384 10.7277 -1.1408 31.8746
CAL-27 GDSC1; CTRP2 2.4647 8.251 1.373 27.6319
BICR 22 GDSC1; CTRP2 2.6258 8.3725 1.4945 26.7421
BICR 10 GDSC1 2.8936 9.2208 0.0083 25.2204
PCI-30 GDSC1 3.0132 8.1933 0.6244 21.3122
SCC-25 GDSC1; CTRP2 3.1603 8.3872 2.0497 23.2452
HSC-3 GDSC1; CTRP2 3.2267 12.0466 0.462 28.2839
PE/CA-PJ49 CTRP2 3.5268 10.229 1.6074 23.8202
SCC-4 GDSC1; CTRP2 3.8708 10.2747 1.9263 21.7829
PCI-15A GDSC1 3.972 7.8821 1.5584 11.5529
UPCI-SCC-090 GDSC1 4.1146 11.231 0.007 20.8143
PE/CA-PJ15 GDSC1; CTRP2 4.1384 11.5257 1.5891 22.3125
BHY GDSC1; CTRP2 4.2673 12.0595 1.4523 22.4707
SCC-9 GDSC1; CTRP2 4.3503 12.7325 1.2014 23.1182
BICR 6 CTRP2 4.5636 9.6857 2.8793 16.4213
CAL-33 GDSC1; CTRP2 4.5787 8.7465 3.3379 14.5521
PE/CA-PJ34 (clone C12) CTRP2 4.5938 11.3372 2.1095 19.3252
BICR 16 CTRP2 4.6705 10.0321 2.8152 16.4202
BICR 31 CTRP2 4.7856 10.9169 2.4933 17.4137
FaDu CTRP2 5.4928 13.1594 2.0174 17.6568
SNU-1066 CTRP2 5.6146 13.8193 1.7932 18.2203
SNU-899 CTRP2 5.639 11.0302 3.206 12.6944
HSC-2 GDSC1; CTRP2 5.8401 13.1551 2.3174 15.8063
PE/CA-PJ41 (clone D2) CTRP2 5.8437 14.7339 1.5313 18.6764
SNU-46 CTRP2 5.963 16.1994 0.8989 20.5513
YD-8 CTRP2 6.0892 14.7571 1.7253 17.4961
HSC-4 GDSC1; CTRP2 7.6218 13.2063 3.6776 7.2601
SNU-1041 CTRP2 7.9108 17.6573 1.7105 14.2653
SNU-1076 CTRP2 8.9513 19.2311 1.6883 12.7325
BICR 56 CTRP2 9.2059 16.0362 3.3729 6.3338
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW780 GDSC1 0.5072 9.6594 -2.4164 43.4224
5637 GDSC1; CTRP2 0.9215 4.773 0.7424 34.6998
647V GDSC1; CTRP2 1.4707 5.2357 1.2482 31.21
UM-UC-1 CTRP2 2.2602 8.9953 0.8543 29.9087
VM-CUB-1 CTRP2 3.0192 9.1368 1.5834 25.2981
SCaBER CTRP2 3.4199 11.6863 0.8205 26.6954
JMSU-1 CTRP2 3.5393 10.878 1.3178 24.7775
HT-1376 GDSC1; CTRP2 4.3933 10.8093 2.1769 19.552
KU-19-19 GDSC1; CTRP2 4.3934 11.6837 1.7533 21.1077
HT-1197 GDSC1; CTRP2 4.5106 12.8724 1.2808 29.4298
U-BLC1 CTRP2 4.5171 9.423 2.9593 16.216
RT-4 GDSC1; CTRP2 4.9601 12.1647 2.0395 18.7404
253J-BV CTRP2 5.4336 13.3206 1.8855 18.2678
KMBC-2 CTRP2 5.7154 12.5035 2.5367 15.2146
253J CTRP2 5.7528 12.2385 2.7012 14.492
SW1710 GDSC1; CTRP2 6.1163 18.0534 0.0997 22.6626
RT-112 GDSC1; CTRP2 6.2779 10.5829 3.9667 8.2873
TCCSUP GDSC1; CTRP2 6.942 13.0244 3.2713 9.9758
T24 GDSC1; CTRP2 6.996 13.204 3.2234 10.0768
CAL-29 GDSC1; CTRP2 7.6133 22.1614 -0.7468 22.1913
UM-UC-3 GDSC1; CTRP2 8.0346 15.624 2.7948 10.0957
BC-3C CTRP2 8.6235 17.8562 2.1253 11.6885
J82 GDSC1; CTRP2 9.7367 22.6094 0.6006 15.0904
BFTC-905 GDSC1; CTRP2 9.7826 36.1708 -6.0282 28.7267
639V GDSC1; CTRP2 10.2424 20.2082 2.0806 9.6529
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NT2-D1 GDSC1 -2.8969 1.0596 -3.0074 71.3197
SW962 GDSC1 -1.5063 4.427 -2.2857 56.4871
TC-YIK GDSC1 -1.4286 2.0332 -1.576 57.967
OVCA420 GDSC1 -1.0344 5.7296 -2.2533 52.5434
BPH-1 GDSC1 -1.0293 4.0787 -1.6531 53.0548
NEC8 GDSC1 -1.003 1.0562 -1.0214 53.9473
OV17R GDSC1 -0.767 3.8191 -1.2855 50.8262
Ca Ski GDSC1 -0.4542 4.3067 -1.1046 47.9653
HT-3 GDSC1 0.0563 3.971 -0.4381 42.6145
ME-180 GDSC1 0.0597 5.3932 -0.9593 43.7808
SiHa GDSC1 0.6667 8.5481 -1.7361 41.5649
MS751 GDSC1 0.7053 5.3108 -0.2455 37.3831
KGN GDSC1 0.7182 5.4464 -0.2884 37.4607
OVMIU GDSC1 0.7466 5.2408 -0.1732 36.8392
C-4-I GDSC1 0.7772 10.1426 -2.387 42.1021
JAR GDSC1 0.8144 4.1316 0.3282 34.1368
CAL-39 GDSC1 1.2416 6.5831 -0.2539 34.2143
SiSo GDSC1 1.3481 5.7595 0.2265 31.432
SKN GDSC1 1.5267 9.3359 -1.2867 36.2708
HEC-1 GDSC1 1.8692 4.5021 1.3098 21.9964
SW756 GDSC1 1.9084 11.7827 -2.1374 36.7921
PEO1 GDSC1 2.2242 6.6972 0.6504 24.57
C-33 A GDSC1 2.3153 8.6344 -0.2137 28.729
DoTc2 4510 GDSC1 2.3352 7.4216 0.4011 25.511
OVCA433 GDSC1 2.9121 8.4921 0.3879 23.1088
ACC-OV7 GDSC1 2.9164 7.6825 0.7951 20.6414
HEY GDSC1 3.0766 5.2814 2.1309 10.3153
DSH1 GDSC1 3.3087 8.1126 0.9156 18.3265
LB831-BLC GDSC1 3.3437 9.568 0.217 22.382
OMC-1 [Human cervical carcinoma] GDSC1 3.5305 8.5361 0.8866 17.6996
SKG-IIIa GDSC1 3.5576 13.923 -1.7835 29.9345
JEG-3 GDSC1 3.7279 11.1679 -0.268 23.481
PWR-1E GDSC1 3.834 7.5077 1.639 11.4023
UWB1.289 GDSC1 3.84 8.5535 1.1243 15.0432
JHOS-3 GDSC1 3.8856 8.1322 1.3689 13.1929
HeLa GDSC1; CTRP2 7.0479 11.6498 4.0276 6.719
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug

References

1 Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia. Nature. 2011 Oct 2;478(7370):529-33.
2 The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer. Oncogene. 2017 Jan 5;36(1):122-132. doi: 10.1038/onc.2016.184. Epub 2016 Jun 13.
3 BRD4 is a novel therapeutic target for liver fibrosis. Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):15713-8. doi: 10.1073/pnas.1522163112. Epub 2015 Dec 7.
4 BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by Downregulating FoxM1. Theranostics. 2016 Jan 1;6(2):219-30. doi: 10.7150/thno.13178. eCollection 2016.
5 Synergistic activity of BET protein antagonist-based combinations in mantle cell lymphoma cells sensitive or resistant to ibrutinib. Blood. 2015 Sep 24;126(13):1565-74.