Details of the Drug

General Information of Drug (ID: DMZ01PS)

Drug Name
PEGylated leptin
Synonyms PEG-Leptin; PEGylated leptin (obesity/type 1 diabetes); PEGylated leptin (obesity/type 1 diabetes), Ambrx
Indication
Disease Entry ICD 11 Status REF
Obesity 5B81 Investigative [1]
Cross-matching ID
TTD ID
D06GZW

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Leptin receptor (LEPR) TT0HD6V LEPR_HUMAN Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Obesity
ICD Disease Classification 5B81
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Leptin receptor (LEPR) DTT LEPR 5.82E-02 0.05 0.15
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1712).